Clinical Practice Guidelines Example Implmentation Guide - Hepatitis B Vaccination
1.0.0 - ci-build International flag

Clinical Practice Guidelines Example Implmentation Guide - Hepatitis B Vaccination, published by HL7 International - Clinical Decision Support WG. This guide is not an authorized publication; it is the continuous build for version 1.0.0 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/cqframework/cpg-example-hepb/ and changes regularly. See the Directory of published versions

Library: Logic for Immunization Forecasting of Hepatitis B Vaccine for Adults >= 18 Years of Age (Experimental)

Official URL: http://hl7.org/fhir/uv/cpg/hepb/Library/HepBAdultForecasting Version: 1.0.0
Active as of 2024-08-23 Computable Name: HepBAdultForecasting
Other Identifiers: HepBAdultForecasting (use: official, )

Usage:Clinical Focus: Immunization/vaccination management (procedure)

If an adult patient has not been immunized for Hep B and is indicated for a Hep B vaccine, providers should administer according to this forecast.

Example artifact implementation of CDC ACIP Hep B vaccination guidelines for adults, 18 years and older, who have not yet been immunized.

Generated Narrative: Library HepBAdultForecasting

Participants

AuthorDaryl Chertcoff
AuthorBryn Rhodes

Related Artifacts

DocumentationImmunization Calculation Engine - Hep B Vaccine Group - Hep B 2-dose Adult Serieshttps://cdsframework.atlassian.net/wiki/spaces/ICE/pages/14352491/Hep+B+Vaccine+Group#HepBVaccineGroup-ImmunizationSeries:HepB2-doseAdultSeries
DocumentationCDC MMWR Vol.67 / No.1 : Prevention of Hepatitis B Virus Infection in the United States: Recommendations of the Advisory Committee on Immunization Practiceshttp://www.cdc.gov/mmwr/volumes/67/rr/pdfs/rr6701-H.PDF
DocumentationApril 2018 Recommendations for the use of adjuvanted hepatitis B vaccine (Heplisav-B, Dynavax)https://www.cdc.gov/mmwr/volumes/67/wr/pdfs/mm6715a5-H.pdf
Depends OnCode System CVXVaccine Administered Code Set (CVX)
Depends OnCode System Immunization Evaluation Dose Status codesImmunization Evaluation Dose Status codes
Depends OnValue Set All Hep B Vaccineshttp://example.org/fhir/uv/cpg/ValueSet/all-hepb-vaccines

Parameters

Patientout01Patient
PatientBirthDateout01date
Age in Days when Patient is 18 Years minus 4 Daysout01integer
Patient is 18 Years Minus 4 Days or Olderout01boolean
No Hep B Shots were Administered before 18 Years minus 4 Days of Ageout01boolean
Hep B Vaccine, Adjuvanted Immunizationout0*Immunization
First Valid Hep B Adjuvanted Adult Doseout01Immunization
There Exists a Valid First Hep B Adjuvanted Doseout01boolean
There Exists a Valid Second Hep B Adjuvanted Doseout01boolean
Patient Hep B Immunization History should be Evaluated in Adult Seriesout01boolean
Get Recommendation Overviewout01string
A Forecast for Hep B Adult Dose 1 Should be Madeout01boolean
A Forecast for Hep B Adult Dose 2 Should be Madeout01boolean
Most Recent Hep B Adjuvanted Administration Dateout01Resource
Patient has Completed the Hep B Adult Seriesout01boolean
Get Recommendation Detailout01string
Second Valid Hep B Adjuvanted Adult Doseout01Immunization

Data Requirements

Type: Immunization (Immunization)
FilterValue
vaccineCodeIn ValueSet http://example.org/fhir/uv/cpg/ValueSet/all-hepb-vaccines
Type: Immunization (Immunization)
FilterValue
vaccineCodeOne of these codes: Vaccine Administered Code Set (CVX) 189: Hepatitis B vaccine (recombinant), CpG adjuvanted

Contents

text/cql

/*
  This example describes the logic of the Hepatitis B (Hep B) immunization schedule for adults who are 18 years or older and have not yet been vaccinated for Hep B.
  It is provided for demonstration purposes and not intended to be a complete representation of all of the Hep B immunization schedule logic.
  See accompanying documentation for additional details and references.
*/
library HepBAdultForecasting version '0.1.0'

using FHIR version '4.0.1'

include FHIRHelpers version '4.0.1' called FHIRHelpers

codesystem CVX: 'http://hl7.org/fhir/sid/cvx'
codesystem "Immunization Evaluation Dose Status codes": 'http://terminology.hl7.org/CodeSystem/immunization-evaluation-dose-status'

// Valuesets
valueset "All Hep B Vaccines": 'http://example.org/fhir/uv/cpg/ValueSet/all-hepb-vaccines'


// Hep B Vaccine Codes
code "DTaP-IPV-Hib-Hep B, historical": '132' from "CVX"
code "DTaP, IPV, Hib, Hep B": '146' from "CVX"
code "DTaP-Hep B-IPV": '110' from "CVX"
code "DTP-Hib-Hep B": '102' from "CVX"
code "Hep A-Hep B": '104' from "CVX"
code "Hep B, adolescent/high risk infant": '42' from "CVX"
code "Hep B, adult": '43' from "CVX"
code "Hep B, dialysis": '44' from "CVX"
code "Hep B, unspecified formulation": '45' from "CVX"
code "Hep B Vaccine Code, Adjuvanted": '189' from "CVX"
code "Hib-Hep B": '51' from "CVX"

// Evaluation Status Code
code "Valid Evaluation Status": 'valid' from "Immunization Evaluation Dose Status codes"

// Concept
concept "Hep B Vaccine, Adjuvanted": { "Hep B Vaccine Code, Adjuvanted" }


context Patient

define "Patient Hep B Immunization History should be Evaluated in Adult Series":
  "Patient is 18 Years Minus 4 Days or Older" and "No Hep B Shots were Administered before 18 Years minus 4 Days of Age"
  or
  "There Exists a Valid First Hep B Adjuvanted Dose"
  or
  "There Exists a Valid Second Hep B Adjuvanted Dose"

define "Patient is 18 Years Minus 4 Days or Older":
  AgeInDays() >= "Age in Days when Patient is 18 Years minus 4 Days"

define "No Hep B Shots were Administered before 18 Years minus 4 Days of Age":
  not exists([Immunization: vaccineCode in "All Hep B Vaccines"] NI
    where NI.occurrence is date and AgeInDaysAt(NI.occurrence.value) < "Age in Days when Patient is 18 Years minus 4 Days"
  )

////////////////////////////////////////////////////////
// Recommendation/Forecast
////////////////////////////////////////////////////////
define "Get Recommendation Overview":
  'Immunization Forecast of Hepatitis B, Adjuvanted Vaccine for Adults 18 Years of Age or Older'

define "Get Recommendation Detail":
  case
    when "A Forecast for Hep B Adult Dose 1 Should be Made"
      then 'Dose 1 of the Hepatitus B, adjuvanted vaccine (CVX 189) is recommended to be administered on ' + ToString(PatientBirthDate + 18 years) + '.'
    when "A Forecast for Hep B Adult Dose 2 Should be Made"
      then 'Dose 2 of the Hepatitis B, adjuvanted vaccine (CVX 189) is recommended to be administered on ' + ToString("Most Recent Hep B Adjuvanted Administration Date" + 28 days) + '.'
    when "Patient has Completed the Hep B Adult Series"
      then 'The patient has already received 2 doses of the Hepatitis B, adjuvanted vaccine (CVX 189), and has completed the series. No additional doses are recommeneded at this time.'
    else
      'A forecast could not be determined at this time.'
  end

define "A Forecast for Hep B Adult Dose 1 Should be Made":
  if
    "Patient Hep B Immunization History should be Evaluated in Adult Series" and "There Exists a Valid First Hep B Adjuvanted Dose" = false
  then
    true
  else
    false

define "A Forecast for Hep B Adult Dose 2 Should be Made":
  "There Exists a Valid First Hep B Adjuvanted Dose" = true and "There Exists a Valid Second Hep B Adjuvanted Dose" = false

define "Patient has Completed the Hep B Adult Series":
  "There Exists a Valid First Hep B Adjuvanted Dose" = true and "There Exists a Valid Second Hep B Adjuvanted Dose" = true


////////////////////////////////////////////////////////
// Evaluation
////////////////////////////////////////////////////////
define "Hep B Vaccine, Adjuvanted Immunization":
  [Immunization: vaccineCode in "Hep B Vaccine, Adjuvanted"]

define "Most Recent Hep B Adjuvanted Administration Date":
  First(
    "Hep B Vaccine, Adjuvanted Immunization" I
      without "Hep B Vaccine, Adjuvanted Immunization" NI
        such that I.occurrence.value is DateTime and NI.occurrence.value is DateTime and NI.occurrence.value after I.occurrence.value
      where I.occurrence.value is DateTime
      return I.occurrence.value
  )

define "There Exists a Valid First Hep B Adjuvanted Dose":
  if "First Valid Hep B Adjuvanted Adult Dose" != null
    then
      true
  else
    false

define "First Valid Hep B Adjuvanted Adult Dose":
  First(
    "Hep B Vaccine, Adjuvanted Immunization" I
      without "Hep B Vaccine, Adjuvanted Immunization" NI
        such that I.occurrence.value is DateTime and AgeInDaysAt(I.occurrence.value) >= "Age in Days when Patient is 18 Years minus 4 Days"
          and NI.occurrence.value is DateTime and NI.occurrence.value before I.occurrence.value
      where I.occurrence.value is DateTime
  )

define "There Exists a Valid Second Hep B Adjuvanted Dose":
  if "There Exists a Valid First Hep B Adjuvanted Dose"
    then
      true
  else
    false

define "Second Valid Hep B Adjuvanted Adult Dose":
  if "There Exists a Valid First Hep B Adjuvanted Dose"
    then
      First(
         "Hep B Vaccine, Adjuvanted Immunization" I
          let firstDoseDate: "First Valid Hep B Adjuvanted Adult Dose".occurrence
          without "Hep B Vaccine, Adjuvanted Immunization" NI
            // where the date is at least 24 days after the most recent shot of Hep B Adjuvant
            such that NI.occurrence.value is DateTime and NI.occurrence.value after firstDoseDate.value and NI.occurrence.value before I.occurrence.value
          where I.occurrence.value is DateTime and I.occurrence.value 24 days or more after firstDoseDate.value
        )
    else
      null

define PatientBirthDate:
  Patient.birthDate.value

define "Age in Days when Patient is 18 Years minus 4 Days":
  CalculateAgeInDaysAt(PatientBirthDate, PatientBirthDate + 18 years - 4 days)

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