WHO Immunization Implementation Guide
0.2.0 - ci-build
WHO Immunization Implementation Guide, published by WHO. This guide is not an authorized publication; it is the continuous build for version 0.2.0 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/WorldHealthOrganization/smart-immunizations/ and changes regularly. See the Directory of published versions
| Draft as of 2025-09-17 |
<PlanDefinition xmlns="http://hl7.org/fhir">
<id value="IMMZD2DTDengueSeropos"/>
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<div>
<table class="grid dict">
<tr>
<th scope="row"><b>Id: </b></th>
<td style="padding-left: 4px;">IMMZD2DTDengueSeropos</td>
</tr>
<tr>
<th scope="row"><b>Url: </b></th>
<td style="padding-left: 4px;"><a href="PlanDefinition-IMMZD2DTDengueSeropos.html">IMMZ.D2.DT.Dengue.3 doses with pre-vaccination screening</a></td>
</tr>
<tr>
<th scope="row"><b>Version: </b></th>
<td style="padding-left: 4px;">0.2.0</td>
</tr>
<tr>
<th scope="row"><b>Title: </b></th>
<td style="padding-left: 4px;">IMMZ.D2.DT.Dengue.3 doses with pre-vaccination screening</td>
</tr>
<tr>
<th scope="row"><b>Status: </b></th>
<td style="padding-left: 4px;">draft</td>
</tr>
<tr>
<th scope="row"><b>Type: </b></th>
<td style="padding-left: 4px;">
<p style="margin-bottom: 5px;">
<b>system: </b> <span><a href="http://terminology.hl7.org/6.5.0/CodeSystem-plan-definition-type.html">http://terminology.hl7.org/CodeSystem/plan-definition-type</a></span>
</p>
<p style="margin-bottom: 5px;">
<b>code: </b> <span>eca-rule</span>
</p>
</td>
</tr>
<tr>
<th scope="row"><b>Date: </b></th>
<td style="padding-left: 4px;">2025-09-17 23:03:28+0000</td>
</tr>
<tr>
<th scope="row"><b>Publisher: </b></th>
<td style="padding-left: 4px;">WHO</td>
</tr>
<tr>
<th scope="row"><b>Description: </b></th>
<td style="padding-left: 4px;"><div><p>IMMZ.D2.DT.Dengue.3 doses with pre-vaccination screening
CYD-TDV (Dengvaxia), 3-dose schedule with pre-vaccination screening, the recommended strategy where feasible (pre-vaccination screening whereby only those tested seropositive would be vaccinated)</p>
</div></td>
</tr>
<tr>
<th scope="row"><b>Knowledge Capability: </b></th>
<td style="padding-left: 4px;">
computable
</td>
</tr>
<tr>
<th scope="row"><b>Related Artifacts: </b></th>
<td style="padding-left: 4px;">
<p><b>References</b></p>
<ul>
<li><div><p>WHO recommendations for routine immunization - summary tables (January 2025)</p>
</div><br/><a href="null"/></li>
</ul>
</td>
</tr>
<tr>
<th scope="row"><b>Libraries: </b></th>
<td style="padding-left: 4px;">
<table class="grid-dict">
<tr>
<td><a href="Library-IMMZD2DTDengueSeroposLogic.html">IMMZD2DTDengueSeroposLogic</a></td>
</tr>
</table>
</td>
</tr>
<tr>
<th scope="row"><b>Actions: </b></th>
<td style="padding-left: 4px;">
<table class="grid-dict">
<tr>
<td>
<b> Determine if the client is due for Dengue.:</b> Determine if the client is due for Dengue vaccine according to the national immunization protocol.
CYD-TDV (Dengvaxia), 3-dose schedule with pre-vaccination screening, the recommended strategy where
feasible (pre-vaccination screening whereby only those tested seropositive would be vaccinated)
<br/>
<b>If:</b>
<i>Applicability:</i>
Client is due for dengue vaccination
<i>(Client is due for dengue vaccination)</i>
<br/>
<b>Then:</b> <i>Definition:</i> <a href="ActivityDefinition-IMMZD2DTDengueMR.html">IMMZ.D2.DT.Dengue.MR</a><br/>
<i>Dynamic Values:</i><br/>
status: <i>('draft')</i>
<br/>
intent: <i>('proposal')</i>
<br/>
</td>
</tr>
<tr>
<td>
<b> Check for Guidance for the patient regarding IMMZ.D2.DT.Dengue.3 doses with pre-vaccination screening.:</b> Show Guidance for the patient regarding IMMZ.D2.DT.Dengue.3 doses with pre-vaccination screening.
<br/>
<b>If:</b>
<i>Applicability:</i>
Has Guidance
<i>(Has Guidance)</i>
<br/>
<b>Then:</b> <i>Definition:</i> <a href="ActivityDefinition-IMMZD2DTCR.html">IMMZ.D2.DT.CR</a><br/>
<i>Dynamic Values:</i><br/>
status: <i>('active')</i>
<br/>
payload.contentString: <i>(Guidance)</i>
<br/>
category.coding: <i>(Code { system: 'http://terminology.hl7.org/CodeSystem/communication-category', code: 'alert' })</i>
<br/>
priority: <i>(Code { system: 'http://hl7.org/fhir/request-priority', code: 'routine' })</i>
<br/>
</td>
</tr>
</table>
</td>
</tr>
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value="http://smart.who.int/immunizations/PlanDefinition/IMMZD2DTDengueSeropos"/>
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<name value="IMMZD2DTDengueSeropos"/>
<title value="IMMZ.D2.DT.Dengue.3 doses with pre-vaccination screening"/>
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<date value="2025-09-17T23:03:28+00:00"/>
<publisher value="WHO"/>
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<description
value="IMMZ.D2.DT.Dengue.3 doses with pre-vaccination screening
CYD-TDV (Dengvaxia), 3-dose schedule with pre-vaccination screening, the recommended strategy where feasible (pre-vaccination screening whereby only those tested seropositive would be vaccinated)"/>
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<type value="citation"/>
<citation
value="WHO recommendations for routine immunization - summary tables (January 2025)"/>
</relatedArtifact>
<library
value="http://smart.who.int/immunizations/Library/IMMZD2DTDengueSeroposLogic"/>
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<extension
url="http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-rationale">
<valueMarkdown
value="Currently, the dengue vaccine should be used within the indicated age range, which in most countries is 9–45 years.
Because of the excess risk of hospitalized dengue identified among seronegative trial
participants who became infected after vaccination, the WHO Global Advisory Committee on Vaccine
Safety (GACVS) concluded that individuals who have not been infected with the wild dengue virus
(i.e. who are seronegative) should not be vaccinated with CYD-TDV (Dengvaxia).
If pre-vaccination screening is not feasible, vaccination without individual screening could be
considered in areas with recent documentation of seroprevalence rates of at least 80% by age 9 years.
Communication needs to ensure appropriate and full disclosure of the risks of vaccination of persons
with unknown serostatus.
Pre-vaccination screening is necessary to avoid vaccinating truly seronegative persons.
CYD-TDV is recommended as a 3-dose series given 6 months apart. Should a vaccine dose be delayed for any reason, it is not
necessary to restart the course and the next dose in the series should be administered as soon as possible."/>
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<title value="Determine if the client is due for Dengue."/>
<description
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CYD-TDV (Dengvaxia), 3-dose schedule with pre-vaccination screening, the recommended strategy where
feasible (pre-vaccination screening whereby only those tested seropositive would be vaccinated)"/>
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<title
value="Check for Guidance for the patient regarding IMMZ.D2.DT.Dengue.3 doses with pre-vaccination screening."/>
<description
value="Show Guidance for the patient regarding IMMZ.D2.DT.Dengue.3 doses with pre-vaccination screening."/>
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<description value="Alert priority"/>
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</expression>
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