Metadata Title Pertuzumab與Trastuzumab皮下注射複方製劑給付規定(早期乳癌)-PertuzumabTrastuzumabSC Rule1 Version 1.0.0 Status Draft Description 此 Library 為乳癌(早期乳癌)患者於申請使用 Pertuzumab與Trastuzumab皮下注射複方製劑 之給付檢核條件。 Type logic-library from http://terminology.hl7.org/CodeSystem/library-type Parameters Parameter None Library Content CQL Content //早期乳癌_Pertuzumab與Trastuzumab_皮下(SC)給付規定 library BCPertuzumabTrastuzumabSCRule1 version '1.0.0' using FHIR version '4.0.1' include FHIRHelpers version '4.0.1' called FHIRHelpers include BCCodeConcept version '1.0.0' called CodeConcept include BCReusable version '1.0.0' called Reusable context Patient //============================================ // 主要規定一：初次使用條件 //============================================ /*規則1*/ define "ICD代碼檢核_布林值": Reusable."ICD-10使用C50" define "醫令類別為1_布林值":Reusable."醫令類別為1" //1條件1:本藥品及化學療法併用 define "1條件1=PertuzumabTrastuzumabSC之用藥申請與化學療法併用": Reusable."HasConcurrentMedicationOrder"(CodeConcept."L01FY01", CodeConcept."併用化學治療法") and Reusable."醫令類別為1" //1條件2:具HER2過度表現(IHC3+或FISH+) define "1條件2=檢驗檢查-具HER2過度表現": Reusable."HasHER2OverexpressionTest" define "1條件2=基因檢測-具HER2過度表現": Reusable."HasHER2OverexpressionGene" define "1條件2=具HER2過度表現": "1條件2=檢驗檢查-具HER2過度表現" or "1條件2=基因檢測-具HER2過度表現" //1條件3:具腋下淋巴結轉移 define "1條件3=具腋下淋巴結轉移(癌症分期分數或結果為N>=1)": exists ( [Observation] O where exists ( O.code.coding Cdg where Cdg.code = '399390009' and Cdg in CodeConcept.SNOMED ) and O.value is not null and O.value is FHIR.string and Matches((O.value as FHIR.string).value, '.*N[^0][a-zA-Z]?.*') ) //1條件4:無遠處臟器轉移之早期乳癌病人 //1條件4-1 define "1條件4-1=3個月內影像報告": Reusable."HasRecentImageReport"("本次申請起始日期", 90) //1條件4-2 define "1條件4-2=癌症分期分數或結果為M=0": Reusable."癌症分期分數或結果為M=0" //1條件4-3(檢查報告) define "1條件4-3=3個月內有檢查報告": Reusable."HasRecentMolecularReport"("本次申請起始日期", 90) define "1條件4=無遠處臟器轉移之早期乳癌病人": "ICD代碼檢核_布林值" and "1條件4-2=癌症分期分數或結果為M=0" and "1條件4-3=3個月內有檢查報告" or "1條件4-1=3個月內影像報告" //規則1 define "規則1": "1條件1=PertuzumabTrastuzumabSC之用藥申請與化學療法併用" and "1條件2=具HER2過度表現" and "1條件3=具腋下淋巴結轉移(癌症分期分數或結果為N>=1)" and "1條件4=無遠處臟器轉移之早期乳癌病人" /*規則2*/ //手術(或其他處置)日期 define "手術日期(opdate)": Max( flatten( [Claim] C return ( C.procedure Proc where Proc.date is not null return FHIRHelpers.ToDateTime(Proc.date) ) ) ) define "手術(或其他處置)項目": exists ( [Claim] C where exists ( C.procedure Proc where exists ( ((Proc.procedure as FHIR.CodeableConcept).coding) Cdg where Cdg is not null and (Cdg.code in CodeConcept."ICD10PCS2023Image" or Cdg.code in CodeConcept."ICD10PCS2014Image") and Cdg.code in CodeConcept."ProcedureCodes" ) ) ) //2條件1 //2條件1-1:使用於術前輔助治療 define "2條件1-1=使用於術前輔助治療": exists ( [MedicationRequest] MRTrastuzumab where MRTrastuzumab.intent = 'order' and Reusable."HasValidTiming"(MRTrastuzumab) and exists ( MRTrastuzumab.medication.coding Cdg where Cdg in CodeConcept.NHIMedication and Cdg.code in CodeConcept."併用化學治療法" ) and Reusable."醫令類別為1" and (start of (MRTrastuzumab.dosageInstruction[0].timing.repeat.bounds as Period)) < "手術日期(opdate)" and "手術(或其他處置)項目" ) //2條件1-2:經外科手術後達病理上完全緩解者（pCR） define "2條件1-2=經外科手術後達病理上完全緩解者（pCR）": exists ( [DiagnosticReport] O2 where exists ( O2.code.coding Cdg where Cdg in CodeConcept.LOINC and Cdg.code = '66110-8' ) and O2.effective is not null and FHIRHelpers.ToDateTime(O2.effective) > "手術日期(opdate)" and ( O2.conclusion is not null and Matches(O2.conclusion, '(?i).*(pCR).*') ) and "手術(或其他處置)項目" ) //2條件1-3 / 2條件2-2 共用規則：療程上限18個（不含日期篩選，由各條件自行加） // 每周療程: count(MR where count=1) ≤ 18 且 sum(useEdate-useSdate) ≤ 126天 define "每周療程得使用至18個療程為上限": Count( [MedicationRequest] MR where MR.intent = 'plan' and exists ( MR.medication.coding Cdg where Cdg in CodeConcept.NHIMedication and Cdg.code in CodeConcept.L01FY01 ) and MR.dosageInstruction[0].timing.repeat.count = 1 ) <= 18 and Sum( [MedicationRequest] MR where MR.intent = 'plan' and exists ( MR.medication.coding Cdg where Cdg in CodeConcept.NHIMedication and Cdg.code in CodeConcept.L01FY01 ) and MR.dosageInstruction[0].timing.repeat.count = 1 and MR.dosageInstruction[0].timing.repeat.bounds is Period and (start of (MR.dosageInstruction[0].timing.repeat.bounds as Period)) is not null and (end of (MR.dosageInstruction[0].timing.repeat.bounds as Period)) is not null return all difference in days between FHIRHelpers.ToDateTime( (MR.dosageInstruction[0].timing.repeat.bounds as Period).start ) and FHIRHelpers.ToDateTime( (MR.dosageInstruction[0].timing.repeat.bounds as Period).end ) ) <= 126 // 每三周療程: 同一起始日視為同一療程，僅保留結束日最晚的代表醫令後，count ≤ 18 且 sum(useEdate-useSdate) ≤ 378天 define "每三周療程得使用至18個療程為上限": // 計算每三周療程的代表療程數 Count( [MedicationRequest] MR where MR.intent = 'plan' and exists ( MR.medication.coding Cdg where Cdg in CodeConcept.NHIMedication and Cdg.code in CodeConcept.L01FY01 ) and MR.dosageInstruction[0].timing.repeat.period = 3 and MR.dosageInstruction[0].timing.repeat.periodUnit.value = 'wk' and Reusable."HasValidTiming"(MR) // 若同一起始日有多筆醫令，只保留結束日最晚者作為該療程代表 and FHIRHelpers.ToDateTime( (MR.dosageInstruction[0].timing.repeat.bounds as Period).end ) = Max( [MedicationRequest] MRSameCourse where MRSameCourse.intent = 'plan' and exists ( MRSameCourse.medication.coding SameCdg where SameCdg in CodeConcept.NHIMedication and SameCdg.code in CodeConcept.L01FY01 ) and MRSameCourse.dosageInstruction[0].timing.repeat.period = 3 and MRSameCourse.dosageInstruction[0].timing.repeat.periodUnit.value = 'wk' and Reusable."HasValidTiming"(MRSameCourse) and FHIRHelpers.ToDateTime( (MRSameCourse.dosageInstruction[0].timing.repeat.bounds as Period).start ) = FHIRHelpers.ToDateTime( (MR.dosageInstruction[0].timing.repeat.bounds as Period).start ) return FHIRHelpers.ToDateTime( (MRSameCourse.dosageInstruction[0].timing.repeat.bounds as Period).end ) ) ) <= 18 // 僅累加代表療程的天數，避免同一療程重複加總 and Sum( [MedicationRequest] MR where MR.intent = 'plan' and exists ( MR.medication.coding Cdg where Cdg in CodeConcept.NHIMedication and Cdg.code in CodeConcept.L01FY01 ) and MR.dosageInstruction[0].timing.repeat.period = 3 and MR.dosageInstruction[0].timing.repeat.periodUnit.value = 'wk' and MR.dosageInstruction[0].timing.repeat.bounds is Period and (start of (MR.dosageInstruction[0].timing.repeat.bounds as Period)) is not null and (end of (MR.dosageInstruction[0].timing.repeat.bounds as Period)) is not null // 若同一起始日有多筆醫令，只保留結束日最晚者作為該療程代表 and FHIRHelpers.ToDateTime( (MR.dosageInstruction[0].timing.repeat.bounds as Period).end ) = Max( [MedicationRequest] MRSameCourse where MRSameCourse.intent = 'plan' and exists ( MRSameCourse.medication.coding SameCdg where SameCdg in CodeConcept.NHIMedication and SameCdg.code in CodeConcept.L01FY01 ) and MRSameCourse.dosageInstruction[0].timing.repeat.period = 3 and MRSameCourse.dosageInstruction[0].timing.repeat.periodUnit.value = 'wk' and Reusable."HasValidTiming"(MRSameCourse) and FHIRHelpers.ToDateTime( (MRSameCourse.dosageInstruction[0].timing.repeat.bounds as Period).start ) = FHIRHelpers.ToDateTime( (MR.dosageInstruction[0].timing.repeat.bounds as Period).start ) return FHIRHelpers.ToDateTime( (MRSameCourse.dosageInstruction[0].timing.repeat.bounds as Period).end ) ) return all difference in days between FHIRHelpers.ToDateTime( (MR.dosageInstruction[0].timing.repeat.bounds as Period).start ) and FHIRHelpers.ToDateTime( (MR.dosageInstruction[0].timing.repeat.bounds as Period).end ) ) <= 378 define "2條件1-3/2條件2-2=療程上限為18個療程": "每周療程得使用至18個療程為上限" or "每三周療程得使用至18個療程為上限" define "2條件1=使用於術前輔助治療，經外科手術後達病理上完全緩解者（pCR），得繼續使用至18個療程為上限": "2條件1-1=使用於術前輔助治療" and "2條件1-2=經外科手術後達病理上完全緩解者（pCR）" and "2條件1-3/2條件2-2=療程上限為18個療程" //2條件2 //2條件2-1:若未接受術前輔助治療，即先行手術者 define "2條件2-1=未接受術前輔助治療，即先行手術者": not exists ( [MedicationRequest] MR where MR.intent = 'order' and MR.status = 'completed' and exists ( MR.medication.coding Cdg where Cdg in CodeConcept.NHIMedication and Cdg.code in CodeConcept."併用化學治療法" ) and FHIRHelpers.ToDateTime((MR.dosageInstruction[0].timing.repeat.bounds as Period).start) < "手術日期(opdate)" and "手術(或其他處置)項目" ) define "2條件2-2=可給予術後輔助治療以18個療程為使用上限": "2條件1-3/2條件2-2=療程上限為18個療程" and exists ( [MedicationRequest] MR where MR.intent = 'plan' and exists ( MR.medication.coding Cdg where Cdg in CodeConcept.NHIMedication and Cdg.code in CodeConcept.L01FY01 ) and MR.dosageInstruction[0].timing.repeat.bounds is Period and FHIRHelpers.ToDateTime((MR.dosageInstruction[0].timing.repeat.bounds as Period).start) > "手術日期(opdate)" ) define "2條件2=若未接受術前輔助治療，即先行手術者，可給予術後輔助治療，以18個療程為使用上限": "2條件2-1=未接受術前輔助治療，即先行手術者" and "2條件2-2=可給予術後輔助治療以18個療程為使用上限" //規則2 define "規則2": "2條件1=使用於術前輔助治療，經外科手術後達病理上完全緩解者（pCR），得繼續使用至18個療程為上限" or "2條件2=若未接受術前輔助治療，即先行手術者，可給予術後輔助治療，以18個療程為使用上限" // 主要規定一 define "主要規定一": "規則1" and "規則2" //============================================ // 主要規定二：續用條件－治療持續給付 //============================================ //條件1:每24週須檢附療效評估資料再次申請，若疾病有惡化情形即不應再行申請 // 本次申請紀錄（以最新一筆申請作為本次申請） define "本次申請紀錄": Reusable."LatestMedicationPlan"(CodeConcept.L01FY01) define "本次申請起始日期": Reusable."GetStartTime"("本次申請紀錄") // 前次申請紀錄（本次申請之前最近一次的申請） define "前次申請紀錄": Reusable."LatestMedicationPlanBefore"(CodeConcept.L01FY01, "本次申請起始日期") // 檢查本次申請療程長度是否在24週內 define "規則1-1=每24週須再次申請並檢附療效評估資料": Reusable."醫令類別為1" and Reusable."續用註記為2" and "本次申請紀錄" is not null and Reusable."HasMedicationPlanPeriodWithinDays"(CodeConcept.L01FY01, 168) //條件2:疾病有惡化情形須停止使用 // 取得前次治療紀錄（最近一次已完成的治療） define "前次治療紀錄": Reusable."LatestCompletedMedicationOrderBefore"(CodeConcept.L01FY01, "本次申請起始日期") // 前次用藥開始日期 define "前次用藥開始日期": Reusable."GetStartTime"("前次治療紀錄") // 規則1-2: 疾病有惡化情形須停止使用(續用須檢附前次治療後影像學報告) define "規則1-2=疾病有惡化情形須停止使用": Reusable."HasImageReportBetweenPreviousTreatmentAndCurrentApply"(CodeConcept.L01FY01) // 主要規定二 define "主要規定二": Reusable."續用註記為2" and Reusable."醫令類別為1" and "本次申請紀錄" is not null and "規則1-1=每24週須再次申請並檢附療效評估資料" and "規則1-2=疾病有惡化情形須停止使用" //============================================ // 主要規定三：藥品使用規則 //============================================ //三種用藥選擇合併療程計算，上限為18個療程 // 每周療程: count(MR where count=1) ≤ 18 且 sum(useEdate-useSdate) ≤ 126天 define "三種用藥合併每周療程上限18個療程": Count( [MedicationRequest] MR where MR.intent = 'plan' and exists ( MR.medication.coding Cdg where Cdg in CodeConcept.NHIMedication and (Cdg.code in CodeConcept.L01FY01 or Cdg.code in CodeConcept.L01FD01 or Cdg.code in CodeConcept.L01FD01andL01FD02exceptKC011362B5) ) and MR.dosageInstruction[0].timing.repeat.count = 1 and Reusable."醫令類別為1" ) <= 18 and Sum( [MedicationRequest] MR where MR.intent = 'plan' and exists ( MR.medication.coding Cdg where Cdg in CodeConcept.NHIMedication and (Cdg.code in CodeConcept.L01FY01 or Cdg.code in CodeConcept.L01FD01 or Cdg.code in CodeConcept.L01FD01andL01FD02exceptKC011362B5) ) and MR.dosageInstruction[0].timing.repeat.count = 1 and MR.dosageInstruction[0].timing.repeat.bounds is Period and (start of (MR.dosageInstruction[0].timing.repeat.bounds as Period)) is not null and (end of (MR.dosageInstruction[0].timing.repeat.bounds as Period)) is not null return all difference in days between FHIRHelpers.ToDateTime( (MR.dosageInstruction[0].timing.repeat.bounds as Period).start ) and FHIRHelpers.ToDateTime( (MR.dosageInstruction[0].timing.repeat.bounds as Period).end ) ) <= 126 // 每三周療程: 同一起始日視為同一療程，僅保留結束日最晚的代表醫令後，count ≤ 18 且 sum(useEdate-useSdate) ≤ 378天 define "三種用藥合併每三周療程上限18個療程": // 計算三種用藥合併後的代表療程數 Count( [MedicationRequest] MR where MR.intent = 'plan' and exists ( MR.medication.coding Cdg where Cdg in CodeConcept.NHIMedication and (Cdg.code in CodeConcept.L01FY01 or Cdg.code in CodeConcept.L01FD01 or Cdg.code in CodeConcept.L01FD01andL01FD02exceptKC011362B5) ) and MR.dosageInstruction[0].timing.repeat.period = 3 and MR.dosageInstruction[0].timing.repeat.periodUnit.value = 'wk' and Reusable."醫令類別為1" and Reusable."HasValidTiming"(MR) // 若同一起始日有多筆藥物，只保留結束日最晚者作為該療程代表 and FHIRHelpers.ToDateTime( (MR.dosageInstruction[0].timing.repeat.bounds as Period).end ) = Max( [MedicationRequest] MRSameCourse where MRSameCourse.intent = 'plan' and exists ( MRSameCourse.medication.coding SameCdg where SameCdg in CodeConcept.NHIMedication and (SameCdg.code in CodeConcept.L01FY01 or SameCdg.code in CodeConcept.L01FD01 or SameCdg.code in CodeConcept.L01FD01andL01FD02exceptKC011362B5) ) and MRSameCourse.dosageInstruction[0].timing.repeat.period = 3 and MRSameCourse.dosageInstruction[0].timing.repeat.periodUnit.value = 'wk' and Reusable."醫令類別為1" and Reusable."HasValidTiming"(MRSameCourse) and FHIRHelpers.ToDateTime( (MRSameCourse.dosageInstruction[0].timing.repeat.bounds as Period).start ) = FHIRHelpers.ToDateTime( (MR.dosageInstruction[0].timing.repeat.bounds as Period).start ) return FHIRHelpers.ToDateTime( (MRSameCourse.dosageInstruction[0].timing.repeat.bounds as Period).end ) ) ) <= 18 // 僅累加代表療程的天數，避免同一療程重複加總 and Sum( [MedicationRequest] MR where MR.intent = 'plan' and exists ( MR.medication.coding Cdg where Cdg in CodeConcept.NHIMedication and (Cdg.code in CodeConcept.L01FY01 or Cdg.code in CodeConcept.L01FD01 or Cdg.code in CodeConcept.L01FD01andL01FD02exceptKC011362B5) ) and MR.dosageInstruction[0].timing.repeat.period = 3 and MR.dosageInstruction[0].timing.repeat.periodUnit.value = 'wk' and MR.dosageInstruction[0].timing.repeat.bounds is Period and (start of (MR.dosageInstruction[0].timing.repeat.bounds as Period)) is not null and (end of (MR.dosageInstruction[0].timing.repeat.bounds as Period)) is not null // 若同一起始日有多筆藥物，只保留結束日最晚者作為該療程代表 and FHIRHelpers.ToDateTime( (MR.dosageInstruction[0].timing.repeat.bounds as Period).end ) = Max( [MedicationRequest] MRSameCourse where MRSameCourse.intent = 'plan' and exists ( MRSameCourse.medication.coding SameCdg where SameCdg in CodeConcept.NHIMedication and (SameCdg.code in CodeConcept.L01FY01 or SameCdg.code in CodeConcept.L01FD01 or SameCdg.code in CodeConcept.L01FD01andL01FD02exceptKC011362B5) ) and MRSameCourse.dosageInstruction[0].timing.repeat.period = 3 and MRSameCourse.dosageInstruction[0].timing.repeat.periodUnit.value = 'wk' and Reusable."醫令類別為1" and Reusable."HasValidTiming"(MRSameCourse) and FHIRHelpers.ToDateTime( (MRSameCourse.dosageInstruction[0].timing.repeat.bounds as Period).start ) = FHIRHelpers.ToDateTime( (MR.dosageInstruction[0].timing.repeat.bounds as Period).start ) return FHIRHelpers.ToDateTime( (MRSameCourse.dosageInstruction[0].timing.repeat.bounds as Period).end ) ) return all difference in days between FHIRHelpers.ToDateTime( (MR.dosageInstruction[0].timing.repeat.bounds as Period).start ) and FHIRHelpers.ToDateTime( (MR.dosageInstruction[0].timing.repeat.bounds as Period).end ) ) <= 378 define "主要規定三": "三種用藥合併每周療程上限18個療程" or "三種用藥合併每三周療程上限18個療程" //============================================ // 列出「符合」項目判斷式 //============================================ define function "符合項目"(): // 主要規定一：初次使用條件 (if Reusable."初次申請" and ( "規則1" or "規則2" ) then '<主要規定一：初次使用條件>\n' + (if "ICD代碼檢核_布林值" then '● 規則1-0：ICD代碼為C50\n' else '') + (if "1條件1=PertuzumabTrastuzumabSC之用藥申請與化學療法併用" then '● 規則1-條件1：本藥品與化學療法併用\n' else '') + (if "1條件2=具HER2過度表現" then '● 規則1-條件2：具HER2過度表現（IHC3+或FISH+）\n' else '') + (if "1條件3=具腋下淋巴結轉移(癌症分期分數或結果為N>=1)" then '● 規則1-條件3：具腋下淋巴結轉移（N≥1）\n' else '') + (if "1條件4-1=3個月內影像報告" then '● 規則1-條件4-1：3個月內影像報告\n' else '') + (if "1條件4-2=癌症分期分數或結果為M=0" then '● 規則1-條件4-2：癌症分期M=0（無遠處臟器轉移）\n' else '') + (if "1條件4-3=3個月內有檢查報告" then '● 規則1-條件4-3：3個月內有檢查報告\n' else '') + (if "2條件1-1=使用於術前輔助治療" then '● 規則2-條件1-1：使用於術前輔助治療\n' else '') + (if "2條件1-2=經外科手術後達病理上完全緩解者（pCR）" then '● 規則2-條件1-2：術後達病理完全緩解（pCR）\n' else '') + (if "2條件1-3/2條件2-2=療程上限為18個療程" then '● 規則2-條件1-3/2-2：療程≤18個療程\n' else '') + (if "2條件2-1=未接受術前輔助治療，即先行手術者" then '● 規則2-條件2-1：未接受術前輔助治療，先行手術\n' else '') + (if "2條件2-2=可給予術後輔助治療以18個療程為使用上限" then '● 規則2-條件2-2：術後輔助治療起始日大於手術日期且療程≤18個療程\n' else '') + '\n' else '') + // 主要規定二：續用條件 (if Reusable."續用申請" and ( "規則1-1=每24週須再次申請並檢附療效評估資料" or "規則1-2=疾病有惡化情形須停止使用" ) then '<主要規定二：續用條件－治療持續給付>\n' + (if "規則1-1=每24週須再次申請並檢附療效評估資料" then '● 續用規則1-1：於24週內再次申請並檢附療效評估資料\n' else '') + (if "規則1-2=疾病有惡化情形須停止使用" then '● 續用規則1-2：已檢附前次治療後影像學報告，確認無惡化\n' else '') + '\n' else '') + // 主要規定三：藥品使用規則 (if "主要規定三" then '<主要規定三：藥品使用規則>\n' + (if "三種用藥合併每周療程上限18個療程" then '● 規則3：每周療程合計≤18個療程且總日數≤126天\n' else '') + (if "三種用藥合併每三周療程上限18個療程" then '● 規則3：每三周療程合計≤18個療程且總日數≤378天\n' else '') + '\n' else '') //============================================ // 列出「不符合」項目判斷式 - 代碼或條件不符 //============================================ define function "不符合項目_代碼或條件不符"(): // 主要規定一：初次使用條件 - 代碼條件不符 (if Reusable."初次申請" and ( not "ICD代碼檢核_布林值" or not "1條件2=具HER2過度表現" or not "1條件3=具腋下淋巴結轉移(癌症分期分數或結果為N>=1)" or not "1條件4-2=癌症分期分數或結果為M=0" ) then '<主要規定一：初次使用條件>\n' + (if not "ICD代碼檢核_布林值" then '▲ 規則1-0：主要疾病之ICD代碼未使用C50\n' else '') + (if not "1條件2=具HER2過度表現" then '▲ 規則1-條件2：HER2未過度表現或未提供（需IHC3+或FISH+）\n' else '') + (if not "1條件3=具腋下淋巴結轉移(癌症分期分數或結果為N>=1)" then '▲ 規則1-條件3：癌症分期不符合（需N≥1，具腋下淋巴結轉移）\n' else '') + (if not "1條件4-2=癌症分期分數或結果為M=0" then '▲ 規則1-條件4：癌症分期不符合（M需為0，無遠處臟器轉移）\n' else '') + '\n' else '') + // 主要規定三：藥品使用規則 - 代碼條件不符 (if not "主要規定三" then '<主要規定三：藥品使用規則>\n' + '▲ 規則3：三種用藥（PertuzumabTrastuzumabSC/Pertuzumab與Trastuzumab/Trastuzumab）合計療程超過18個療程\n' + '\n' else '') //============================================ // 列出「不符合」項目判斷式 - 必要資料未填寫 //============================================ define function "不符合項目_必要資料未填寫"(): // 主要規定一：初次使用條件 - 必要資料未填寫 (if Reusable."初次申請" and ( not "1條件1=PertuzumabTrastuzumabSC之用藥申請與化學療法併用" or not ("1條件4-1=3個月內影像報告" or "1條件4-3=3個月內有檢查報告") or not "規則2" ) then '<主要規定一：初次使用條件>\n' + (if not "1條件1=PertuzumabTrastuzumabSC之用藥申請與化學療法併用" then '▲ 規則1-條件1：未申請本藥品與化學療法併用\n' else '') + (if not ("1條件4-1=3個月內影像報告" or "1條件4-3=3個月內有檢查報告") then '▲ 規則1-條件4：未提供3個月內影像報告或檢查報告\n' else '') + (if not "2條件1-2=經外科手術後達病理上完全緩解者（pCR）" and not "2條件2-1=未接受術前輔助治療，即先行手術者" then '▲ 規則2：未提供術前輔助治療pCR資料，亦不符合先行手術後輔助治療條件\n' else '') + '\n' else '') + // 主要規定二：續用條件 - 必要資料未填寫 (if Reusable."續用申請" and ( not "規則1-1=每24週須再次申請並檢附療效評估資料" or not "規則1-2=疾病有惡化情形須停止使用" ) then '<主要規定二：續用條件－治療持續給付>\n' + (if not "規則1-1=每24週須再次申請並檢附療效評估資料" then '▲ 續用規則1-1：未於24週內再次申請或未檢附療效評估資料\n' else '') + (if not "規則1-2=疾病有惡化情形須停止使用" then '▲ 續用規則1-2：未提供前次治療後影像學報告\n' else '') + '\n' else '') //============================================ // 審核結果 //============================================ define "乳癌PertuzumabTrastuzumabSC申請結果_布林": case when Reusable."初次申請" then ( "主要規定一" and "主要規定三" ) when Reusable."續用申請" then ( "主要規定二" and "主要規定三" ) else false end define "乳癌PertuzumabTrastuzumabSC申請之CQL檢核結果": if ( Reusable."初次申請" and "主要規定一" and "主要規定三" ) then '✓通過：初次使用－早期乳癌 PertuzumabTrastuzumabSC 用藥申請' else if ( Reusable."續用申請" and "主要規定二" and "主要規定三" ) then '✓通過：續用－早期乳癌 PertuzumabTrastuzumabSC 用藥申請' else if Reusable."初次申請" then '✖不通過：初次使用－早期乳癌 PertuzumabTrastuzumabSC 用藥申請' else if Reusable."續用申請" then '✖不通過：續用－早期乳癌 PertuzumabTrastuzumabSC 用藥申請' else '✖不通過：無法判定申請類型－早期乳癌 PertuzumabTrastuzumabSC 用藥申請' //============================================ // 報告總結 //============================================ define "報告總結": '\n=== 早期乳癌之PertuzumabTrastuzumabSC 申請審核報告 ===\n' + '\n【申請類型】' + Reusable."申請類型" + '\n' + '\n【●符合項目】\n' + (if "符合項目"() = '' then '無\n' else "符合項目"()) + '\n【▲不符合項目 - 代碼或條件不符】\n' + (if "不符合項目_代碼或條件不符"() = '' then '無\n' else "不符合項目_代碼或條件不符"()) + '\n【▲不符合項目 - 必要資料未填寫】\n' + (if "不符合項目_必要資料未填寫"() = '' then '無\n' else "不符合項目_必要資料未填寫"()) + '\n【申請結果】\n' + "乳癌PertuzumabTrastuzumabSC申請之CQL檢核結果" + '\n===============================================\n' ELM XML Content Encoded data ELM JSON Content Encoded data Generated using version 0.5.3-cibuild of the sample-content-ig Liquid templates
Pertuzumab與Trastuzumab皮下注射複方製劑給付規定(早期乳癌)-PertuzumabTrastuzumabSC Rule1
此 Library 為乳癌(早期乳癌)患者於申請使用 Pertuzumab與Trastuzumab皮下注射複方製劑 之給付檢核條件。