@prefix fhir: <http://hl7.org/fhir/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix sct: <http://snomed.info/id/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

# - resource -------------------------------------------------------------------

<http://hl7.org.nz/fhir/ig/cca/PlanDefinition/ColoRectal> a fhir:PlanDefinition ;
  fhir:nodeRole fhir:treeRoot ;
  fhir:id [ fhir:v "ColoRectal"] ; # 
  fhir:meta [
     fhir:profile ( [
       fhir:v "http://hl7.org.nz/fhir/StructureDefinition/CcaPlanDefinition"^^xsd:anyURI ;
       fhir:l <http://hl7.org.nz/fhir/StructureDefinition/CcaPlanDefinition>
     ] )
  ] ; # 
  fhir:text [
     fhir:status [ fhir:v "additional" ] ;
     fhir:div [ fhir:v "<div xmlns=\"http://www.w3.org/1999/xhtml\">Plan for ColoRectal cancer. There is a single cycle with 2 drug administrations</div>"^^rdf:XMLLiteral ]
  ] ; # 
  fhir:contained ( [
     a fhir:ActivityDefinition ;
     fhir:id [ fhir:v "ActTragacanth" ] ;
     fhir:meta [
       fhir:profile ( [
         fhir:v "http://hl7.org.nz/fhir/StructureDefinition/CcaActivityDefinition"^^xsd:anyURI ;
         fhir:l <http://hl7.org.nz/fhir/StructureDefinition/CcaActivityDefinition>
       ] )
     ] ;
     fhir:text [
       fhir:status [ fhir:v "additional" ] ;
       fhir:div [ fhir:v "<div xmlns=\"http://www.w3.org/1999/xhtml\">Tragacanth administration, 3mg over 3 hours by continuous IV infusion</div>"^^rdf:XMLLiteral ]
     ] ;
     fhir:status [ fhir:v "draft" ] ;
     fhir:product [
       a fhir:CodeableConcept ;
       fhir:coding ( [
         fhir:system [
           fhir:v "https://nzulm.org.nz/nzmt"^^xsd:anyURI ;
           fhir:l <https://nzulm.org.nz/nzmt>
         ] ;
         fhir:code [ fhir:v "10711851000116105" ] ;
         fhir:display [ fhir:v "Tragacanth" ]
       ] )
     ] ;
     fhir:dosage ( [
       fhir:text [ fhir:v "3 mg over 3 hours by IV infusion" ] ;
       fhir:route [
         fhir:coding ( [
           a sct:180177004 ;
           fhir:system [
             fhir:v "http://snomed.info/sct"^^xsd:anyURI ;
             fhir:l <http://snomed.info/sct>
           ] ;
           fhir:code [ fhir:v "180177004" ] ;
           fhir:display [ fhir:v "continuous intravenous infusion" ]
         ] )
       ] ;
       fhir:doseAndRate ( [
         fhir:dose [
           a fhir:Quantity ;
           fhir:value [ fhir:v "3"^^xsd:decimal ] ;
           fhir:system [
             fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ;
             fhir:l <http://unitsofmeasure.org>
           ] ;
           fhir:code [ fhir:v "mg" ]
         ] ;
         fhir:rate [
           a fhir:Quantity ;
           fhir:value [ fhir:v "3"^^xsd:decimal ] ;
           fhir:system [
             fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ;
             fhir:l <http://unitsofmeasure.org>
           ] ;
           fhir:code [ fhir:v "h" ]
         ]
       ] )
     ] )
  ] ) ; # 
  fhir:extension ( [
     fhir:url [
       fhir:v "http://hl7.org.nz/fhir/StructureDefinition/sact-plan-instructions"^^xsd:anyURI ;
       fhir:l <http://hl7.org.nz/fhir/StructureDefinition/sact-plan-instructions>
     ] ;
     fhir:value [
       a fhir:Markdown ;
       fhir:v "Only for women"
     ]
  ] [
     fhir:url [
       fhir:v "http://hl7.org.nz/fhir/StructureDefinition/sact-disclaimer"^^xsd:anyURI ;
       fhir:l <http://hl7.org.nz/fhir/StructureDefinition/sact-disclaimer>
     ] ;
     fhir:value [
       a fhir:Markdown ;
       fhir:v "Developed with the best of intentions."
     ]
  ] [
     fhir:url [
       fhir:v "http://hl7.org.nz/fhir/StructureDefinition/sact-regimen-type"^^xsd:anyURI ;
       fhir:l <http://hl7.org.nz/fhir/StructureDefinition/sact-regimen-type>
     ] ;
     fhir:value [
       a fhir:CodeableConcept ;
       fhir:coding ( [
         a sct:dummy ;
         fhir:system [
           fhir:v "http://snomed.info/sct"^^xsd:anyURI ;
           fhir:l <http://snomed.info/sct>
         ] ;
         fhir:code [ fhir:v "dummy" ]
       ] ) ;
       fhir:text [ fhir:v "Folfox" ]
     ]
  ] [
     fhir:extension ( [
       fhir:url [
         fhir:v "factor"^^xsd:anyURI ;
         fhir:l fhir:factor
       ] ;
       fhir:value [
         a fhir:CodeableConcept ;
         fhir:coding ( [
           a sct:TOUPDATE-SUPPORT4 ;
           fhir:system [
             fhir:v "http://snomed.info/sct"^^xsd:anyURI ;
             fhir:l <http://snomed.info/sct>
           ] ;
           fhir:code [ fhir:v "TOUPDATE-SUPPORT4" ] ;
           fhir:display [ fhir:v "Diarrhoea risk" ]
         ] )
       ]
     ] [
       fhir:url [
         fhir:v "value"^^xsd:anyURI ;
         fhir:l fhir:value
       ] ;
       fhir:value [
         a fhir:CodeableConcept ;
         fhir:text [ fhir:v "low" ]
       ]
     ] ) ;
     fhir:url [
       fhir:v "http://hl7.org.nz/fhir/StructureDefinition/sact-support-factor"^^xsd:anyURI ;
       fhir:l <http://hl7.org.nz/fhir/StructureDefinition/sact-support-factor>
     ]
  ] [
     fhir:extension ( [
       fhir:url [
         fhir:v "factor"^^xsd:anyURI ;
         fhir:l fhir:factor
       ] ;
       fhir:value [
         a fhir:CodeableConcept ;
         fhir:coding ( [
           a sct:TOUPDATE-SUPPORT8 ;
           fhir:system [
             fhir:v "http://snomed.info/sct"^^xsd:anyURI ;
             fhir:l <http://snomed.info/sct>
           ] ;
           fhir:code [ fhir:v "TOUPDATE-SUPPORT8" ] ;
           fhir:display [ fhir:v "AntiFungal Prophylaxis" ]
         ] )
       ]
     ] [
       fhir:url [
         fhir:v "value"^^xsd:anyURI ;
         fhir:l fhir:value
       ] ;
       fhir:value [
         a fhir:CodeableConcept ;
         fhir:text [ fhir:v "low" ]
       ]
     ] ) ;
     fhir:url [
       fhir:v "http://hl7.org.nz/fhir/StructureDefinition/sact-support-factor"^^xsd:anyURI ;
       fhir:l <http://hl7.org.nz/fhir/StructureDefinition/sact-support-factor>
     ]
  ] [
     fhir:extension ( [
       fhir:url [
         fhir:v "factor"^^xsd:anyURI ;
         fhir:l fhir:factor
       ] ;
       fhir:value [
         a fhir:CodeableConcept ;
         fhir:coding ( [
           a sct:TOUPDATE-SUPPORT2 ;
           fhir:system [
             fhir:v "http://snomed.info/sct"^^xsd:anyURI ;
             fhir:l <http://snomed.info/sct>
           ] ;
           fhir:code [ fhir:v "TOUPDATE-SUPPORT2" ] ;
           fhir:display [ fhir:v "Hypersensitivity / Infusion related reaction ris" ]
         ] )
       ]
     ] [
       fhir:url [
         fhir:v "value"^^xsd:anyURI ;
         fhir:l fhir:value
       ] ;
       fhir:value [
         a fhir:CodeableConcept ;
         fhir:text [ fhir:v "low" ]
       ]
     ] ) ;
     fhir:url [
       fhir:v "http://hl7.org.nz/fhir/StructureDefinition/sact-support-factor"^^xsd:anyURI ;
       fhir:l <http://hl7.org.nz/fhir/StructureDefinition/sact-support-factor>
     ]
  ] ) ; # 
  fhir:url [
     fhir:v "http://hl7.org.nz/fhir/ig/cca/PlanDefinition/ColoRectal"^^xsd:anyURI ;
     fhir:l <http://hl7.org.nz/fhir/ig/cca/PlanDefinition/ColoRectal>
  ] ; # 
  fhir:version [ fhir:v "0.1.0"] ; # 
  fhir:title [ fhir:v "Colorectal Adjuvant FOLFOX (a7)"] ; # 
  fhir:type [
     fhir:coding ( [
       fhir:system [
         fhir:v "http://terminology.hl7.org/CodeSystem/plan-definition-type"^^xsd:anyURI ;
         fhir:l <http://terminology.hl7.org/CodeSystem/plan-definition-type>
       ] ;
       fhir:code [ fhir:v "clinical-protocol" ]
     ] )
  ] ; # 
  fhir:status [
     fhir:v "active" ;
     fhir:extension ( [
       fhir:url [
         fhir:v "http://hl7.org.nz/fhir/StructureDefinition/sact-additional-plan-status"^^xsd:anyURI ;
         fhir:l <http://hl7.org.nz/fhir/StructureDefinition/sact-additional-plan-status>
       ] ;
       fhir:value [
         a fhir:Code ;
         fhir:v "review"
       ]
     ] )
  ] ; # 
  fhir:experimental [ fhir:v false] ; # 
  fhir:date [ fhir:v "2020-06-29T20:14:18.417+12:00"^^xsd:dateTime] ; # 
  fhir:publisher [ fhir:v "Te Aho o Te Kahu, Cancer Control Agency"] ; # 
  fhir:description [ fhir:v "A drug treatment regimen for Colorectal cancer. Plan is still under review."] ; # 
  fhir:useContext ( [
     fhir:code [
       fhir:system [
         fhir:v "http://terminology.hl7.org/CodeSystem/usage-context-type"^^xsd:anyURI ;
         fhir:l <http://terminology.hl7.org/CodeSystem/usage-context-type>
       ] ;
       fhir:code [ fhir:v "focus" ]
     ] ;
     fhir:value [
       a fhir:CodeableConcept ;
       fhir:coding ( [
         a sct:781382000 ;
         fhir:system [
           fhir:v "http://snomed.info/sct"^^xsd:anyURI ;
           fhir:l <http://snomed.info/sct>
         ] ;
         fhir:code [ fhir:v "781382000" ] ;
         fhir:display [ fhir:v "Colorectal cancer" ]
       ] )
     ]
  ] ) ; # 
  fhir:relatedArtifact ( [
     fhir:type [ fhir:v "citation" ] ;
     fhir:display [ fhir:v "test" ] ;
     fhir:url [
       fhir:v "http://www.ncbi.nlm.nih.gov/pubmed/23434"^^xsd:anyURI ;
       fhir:l <http://www.ncbi.nlm.nih.gov/pubmed/23434>
     ] ;
     fhir:document [
       fhir:url [
         fhir:v "http://www.ncbi.nlm.nih.gov/pubmed/23434"^^xsd:anyURI ;
         fhir:l <http://www.ncbi.nlm.nih.gov/pubmed/23434>
       ]
     ]
  ] [
     fhir:type [ fhir:v "citation" ] ;
     fhir:display [ fhir:v "test2" ] ;
     fhir:url [
       fhir:v "http://www.ncbi.nlm.nih.gov/pubmed/34324"^^xsd:anyURI ;
       fhir:l <http://www.ncbi.nlm.nih.gov/pubmed/34324>
     ] ;
     fhir:document [
       fhir:url [
         fhir:v "http://www.ncbi.nlm.nih.gov/pubmed/34324"^^xsd:anyURI ;
         fhir:l <http://www.ncbi.nlm.nih.gov/pubmed/34324>
       ]
     ]
  ] ) ; # 
  fhir:action ( [
     fhir:extension ( [
       fhir:url [
         fhir:v "http://hl7.org.nz/fhir/StructureDefinition/sact-plan-instructions"^^xsd:anyURI ;
         fhir:l <http://hl7.org.nz/fhir/StructureDefinition/sact-plan-instructions>
       ] ;
       fhir:value [
         a fhir:Markdown ;
         fhir:v "Ensure not pregnant before starting"
       ]
     ] ) ;
     fhir:title [ fhir:v "This is the only cycle in the regimen." ] ;
     fhir:description [ fhir:v "Administration of Cabergoline and Tragacanth. Cycle length 14 days" ] ;
     fhir:timing [
       a fhir:Timing ;
       fhir:repeat [
         fhir:count [ fhir:v "1"^^xsd:positiveInteger ] ;
         fhir:duration [ fhir:v "14"^^xsd:decimal ] ;
         fhir:durationUnit [ fhir:v "d" ]
       ]
     ] ;
     fhir:selectionBehavior [ fhir:v "all" ] ;
     fhir:action ( [
       fhir:extension ( [
         fhir:url [
           fhir:v "http://hl7.org.nz/fhir/StructureDefinition/sact-plan-instructions"^^xsd:anyURI ;
           fhir:l <http://hl7.org.nz/fhir/StructureDefinition/sact-plan-instructions>
         ] ;
         fhir:value [
           a fhir:Markdown ;
           fhir:v "Keep a close eye for side effects"
         ]
       ] [
         fhir:extension ( [
           fhir:url [
             fhir:v "day"^^xsd:anyURI ;
             fhir:l fhir:day
           ] ;
           fhir:value [
             a fhir:Integer ;
             fhir:v 1
           ]
         ] [
           fhir:url [
             fhir:v "instructions"^^xsd:anyURI ;
             fhir:l fhir:instructions
           ] ;
           fhir:value [
             a fhir:String ;
             fhir:v "Specific instructions for the day 1 administration"
           ]
         ] ) ;
         fhir:url [
           fhir:v "http://hl7.org.nz/fhir/StructureDefinition/sact-timing-of-days"^^xsd:anyURI ;
           fhir:l <http://hl7.org.nz/fhir/StructureDefinition/sact-timing-of-days>
         ]
       ] [
         fhir:extension ( [
           fhir:url [
             fhir:v "day"^^xsd:anyURI ;
             fhir:l fhir:day
           ] ;
           fhir:value [
             a fhir:Integer ;
             fhir:v 4
           ]
         ] [
           fhir:url [
             fhir:v "instructions"^^xsd:anyURI ;
             fhir:l fhir:instructions
           ] ;
           fhir:value [
             a fhir:String ;
             fhir:v "Specific instructions for the day 4 administration"
           ]
         ] ) ;
         fhir:url [
           fhir:v "http://hl7.org.nz/fhir/StructureDefinition/sact-timing-of-days"^^xsd:anyURI ;
           fhir:l <http://hl7.org.nz/fhir/StructureDefinition/sact-timing-of-days>
         ]
       ] ) ;
       fhir:description [ fhir:v "2mg of Cabergoline daily on days 1 and 4 by IV Infusion over 20 minutes" ] ;
       fhir:definition [
         a fhir:Canonical ;
         fhir:v "#act-cabergoline"^^xsd:anyURI ;
         fhir:l <#act-cabergoline>
       ]
     ] [
       fhir:extension ( [
         fhir:extension ( [
           fhir:url [
             fhir:v "day"^^xsd:anyURI ;
             fhir:l fhir:day
           ] ;
           fhir:value [
             a fhir:Integer ;
             fhir:v 2
           ]
         ] [
           fhir:url [
             fhir:v "instructions"^^xsd:anyURI ;
             fhir:l fhir:instructions
           ] ;
           fhir:value [
             a fhir:String ;
             fhir:v "Specific instructions for the day 2 administration"
           ]
         ] ) ;
         fhir:url [
           fhir:v "http://hl7.org.nz/fhir/StructureDefinition/sact-timing-of-days"^^xsd:anyURI ;
           fhir:l <http://hl7.org.nz/fhir/StructureDefinition/sact-timing-of-days>
         ]
       ] [
         fhir:extension ( [
           fhir:url [
             fhir:v "day"^^xsd:anyURI ;
             fhir:l fhir:day
           ] ;
           fhir:value [
             a fhir:Integer ;
             fhir:v 3
           ]
         ] [
           fhir:url [
             fhir:v "instructions"^^xsd:anyURI ;
             fhir:l fhir:instructions
           ] ;
           fhir:value [
             a fhir:String ;
             fhir:v "Specific instructions for the day 3 administration"
           ]
         ] ) ;
         fhir:url [
           fhir:v "http://hl7.org.nz/fhir/StructureDefinition/sact-timing-of-days"^^xsd:anyURI ;
           fhir:l <http://hl7.org.nz/fhir/StructureDefinition/sact-timing-of-days>
         ]
       ] [
         fhir:extension ( [
           fhir:url [
             fhir:v "day"^^xsd:anyURI ;
             fhir:l fhir:day
           ] ;
           fhir:value [
             a fhir:Integer ;
             fhir:v 4
           ]
         ] [
           fhir:url [
             fhir:v "instructions"^^xsd:anyURI ;
             fhir:l fhir:instructions
           ] ;
           fhir:value [
             a fhir:String ;
             fhir:v "Specific instructions for the day 4 administration"
           ]
         ] ) ;
         fhir:url [
           fhir:v "http://hl7.org.nz/fhir/StructureDefinition/sact-timing-of-days"^^xsd:anyURI ;
           fhir:l <http://hl7.org.nz/fhir/StructureDefinition/sact-timing-of-days>
         ]
       ] ) ;
       fhir:description [ fhir:v "3mg of Tragacanth daily on days 2,3 and 4 by IV Infusion over 3 hours" ] ;
       fhir:definition [
         a fhir:Canonical ;
         fhir:v "#act-tragacanth"^^xsd:anyURI ;
         fhir:l <#act-tragacanth>
       ]
     ] )
  ] ) . # 

# -------------------------------------------------------------------------------------