English

Generated Narrative: Questionnaire questionnaire-pathology-lt-breast

Language: en

Structure
LinkIDTextCardinalityTypeDescription & Constraintsdoco
.. PathologyQuestionnaireLtBreastQuestionnairehttps://hl7.lt/fhir/breast/Questionnaire/questionnaire-pathology-lt-breast#0.0.1
... grp-referralReferral to perform pathology test0..1display
... grp-patientPatient information0..1group
.... patient-personal-codePersonal code0..1string
.... patient-nameName0..1string
.... patient-surnameSurname0..1string
.... patient-birth-dateDate of birth0..1date
.... patient-ageAge0..1integer
.... patient-genderGender0..1codingOptions: 2 options
... grp-specimen-datesSpecimen dates0..1group
.... specimen-collection-dateDate of material collection0..1dateTime
.... specimen-shipment-dateShipment / formation date0..1dateTime
... grp-clinical-diagnosisClinical diagnosis0..1group
.... diagnosis-icd10-codeClinical diagnosis ICD-10-AM code0..1string
.... diagnosis-nameClinical diagnosis name0..1text
... grp-materialMaterial fixation0..1group
.... fixation-typeMaterial fixation type0..1codingOptions: 2 options
... grp-previous-proceduresPrevious procedures and key clinical data0..1group
.... previous-proceduresKey clinical data0..*codingOptions: 7 options
.... previous-procedures-otherOther information0..1text
... grp-special-testsSpecial tests0..1group
.... special-tests-requiredSpecial tests required0..1text
... grp-radiological-dataRadiological examination data0..1group
.... radiology-performedRadiological examination performed0..1codingOptions: 2 options
.... radiology-exam-typeExamination type0..*codingOptions: 3 options
.... radiology-exam-dateExamination date0..1date
.... birads-rightBI-RADS right breast0..1codingOptions: 6 options
.... birads-leftBI-RADS left breast0..1codingOptions: 6 options
... grp-operationOperation details0..1group
.... operation-natureNature of operation0..1codingOptions: 3 options
.... operation-other-detailsOther operation details0..1text
... grp-histological-sampleDescription of histological sample / object0..1group
.... sample-container-infoContainer information0..1text
.... sample-biopsy-locationBiopsy location0..1text
... grp-macroscopicDescription of macroscopic examination0..1group
.... macro-biopsy-sizeBiopsy size (mm)0..1quantity
.... macro-fragment-detailsFragment details0..1text
.... macro-notesNotes0..1text
... grp-microscopicDescription of microscopic examination0..1group
.... microscopic-descriptionMicroscopic examination description0..1text
... grp-ihcImmunohistochemistry (IHC)0..1group
.... ihc-er-statusEstrogen receptors ER0..1codingOptions: 4 options
.... ihc-er-percentER expression in nuclei (%)0..1quantity
.... ihc-pr-statusProgesterone receptors PR0..1codingOptions: 4 options
.... ihc-pr-percentPR expression in nuclei (%)0..1quantity
.... ihc-her2-statusHER2 status0..1codingOptions: 4 options
.... ihc-her2-evaluationHER2 evaluation0..1codingOptions: 4 options
.... ihc-ki67Ki67 proliferation index (%)0..1quantity
... grp-molecularMolecular studies0..1group
.... fish-resultFISH result0..1codingOptions: 7 options
.... fish-her2-averageHER2 average0..1decimal
.... fish-cep17-averageAverage CEP170..1decimal
.... fish-her2-cep17-ratioHER2/CEP17 ratio0..1decimal
.... cish-sish-resultCISH/SISH result0..1codingOptions: 3 options
... grp-conclusionConclusion0..1group
.... conclusion-who-diagnosisWHO Classification diagnosis0..1text
.... conclusion-tumour-gradeTumour grade0..1codingOptions: 4 options
.... conclusion-tumour-sizeTumour size (mm)0..1quantity
.... conclusion-lviLymphovascular invasion0..1codingOptions: 6 options

doco Documentation for this format

Options Sets

Answer options for patient-gender

  • http://hl7.org/fhir/administrative-gender#male ("Male")
  • http://hl7.org/fhir/administrative-gender#female ("Female")

Answer options for fixation-type

  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#fixation-formalin ("Fixed (10% formalin buffered solution)")
  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#fixation-unfixed ("Unfixed")

Answer options for previous-procedures

  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#proc-none ("No important information")
  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#proc-biopsy ("Biopsy")
  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#proc-excision ("Excision")
  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#proc-other-operation ("Other operation")
  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#proc-chemotherapy ("Chemotherapy")
  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#proc-radiation ("Radiation (breast)")
  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#proc-immunotherapy ("Immunotherapy")

Answer options for radiology-performed

  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#yes ("Yes")
  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#no ("No")

Answer options for radiology-exam-type

  • http://snomed.info/sct#71651007 ("Mammography")
  • http://snomed.info/sct#439324009 ("Digital breast tomosynthesis")
  • http://snomed.info/sct#16310003 ("Ultrasonography")

Answer options for birads-right

  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#birads-0 ("BI-RADS 0 – Incomplete examination")
  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#birads-1 ("BI-RADS 1 – No changes found")
  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#birads-2 ("BI-RADS 2 – Benign changes found")
  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#birads-3 ("BI-RADS 3 – Possibly benign changes")
  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#birads-4 ("BI-RADS 4 – Suspicious malignant finding")
  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#birads-5 ("BI-RADS 5 – Highly probable malignant finding")

Answer options for birads-left

  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#birads-0 ("BI-RADS 0 – Incomplete examination")
  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#birads-1 ("BI-RADS 1 – No changes found")
  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#birads-2 ("BI-RADS 2 – Benign changes found")
  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#birads-3 ("BI-RADS 3 – Possibly benign changes")
  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#birads-4 ("BI-RADS 4 – Suspicious malignant finding")
  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#birads-5 ("BI-RADS 5 – Highly probable malignant finding")

Answer options for operation-nature

  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#op-thick-needle-biopsy ("Thick needle biopsy")
  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#op-excision ("Excision")
  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#op-other ("Other (free text)")

Answer options for ihc-er-status

  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#ihc-negative ("Negative")
  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#ihc-weak ("Weak (+)")
  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#ihc-moderate ("Moderate (++)")
  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#ihc-strong ("Strong (+++)")

Answer options for ihc-pr-status

  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#ihc-negative ("Negative")
  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#ihc-weak ("Weak (+)")
  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#ihc-moderate ("Moderate (++)")
  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#ihc-strong ("Strong (+++)")

Answer options for ihc-her2-status

  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#her2-negative ("HER2: expression absent (0)")
  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#her2-low ("HER2: low immunohistochemical expression (1+)")
  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#her2-borderline ("HER2: expression borderline (2+)")
  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#her2-positive ("HER2: expression positive (3+)")

Answer options for ihc-her2-evaluation

  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#her2-eval-0 ("HER2 evaluation: 0+")
  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#her2-eval-1 ("HER2 evaluation: 1+")
  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#her2-eval-2 ("HER2 evaluation: 2+")
  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#her2-eval-3 ("HER2 evaluation: 3+")

Answer options for fish-result

  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#fish-amplified ("FISH: HER2 amplified")
  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#fish-amplified-clusters ("FISH: amplified (clusters)")
  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#fish-co-amplified ("FISH: co-amplified (HER2>=6, HER2/CEP17<2)")
  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#fish-borderline ("FISH: borderline (4<=HER2<6, HER2/CEP17<2)")
  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#fish-monosomic ("FISH: monosomic (HER2<4, HER2/CEP17>=2)")
  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#fish-negative ("FISH: negative (HER2<4, HER2/CEP17<2)")
  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#fish-not-evaluated ("FISH: not to be evaluated")

Answer options for cish-sish-result

  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#cish-amplified ("CISH/SISH: HER2 amplified")
  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#cish-not-amplified ("CISH/SISH: HER2 not amplified")
  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#cish-not-evaluated ("CISH/SISH: not to be evaluated")

Answer options for conclusion-tumour-grade

  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#grade-g1 ("G1 (well-differentiated)")
  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#grade-g2 ("G2 (moderately differentiated)")
  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#grade-g3 ("G3 (poorly differentiated)")
  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#grade-gx ("Gx (degree of differentiation undetermined)")

Answer options for conclusion-lvi

  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#lvi-0 ("pLVI-0: not detected")
  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#lvi-1 ("pLVI-1: spreading, otherwise unclassified")
  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#lvi-2 ("pLVI-2: only in lymphatic vessels and small blood vessels")
  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#lvi-3 ("pLVI-3: only in veins (large, thick-walled blood vessels)")
  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#lvi-4 ("pLVI-4: present in both lymphatic vessels and veins")
  • https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options#lvi-9 ("pLVI-9: undetectable/unknown")
 <status value="active"/> <date value="2026-03-29T12:06:43+00:00"/> <publisher value="Lithuanian Medical Library"/> <contact> <name value="Lithuanian Medical Library"/> <telecom> <system value="url"/> <value value="https://medicinosnk.lt"/> </telecom> <telecom> <system value="email"/> <value value="info@medicinosnk.lt"/> </telecom> </contact> <jurisdiction> <coding> <system value="urn:iso:std:iso:3166"/> <code value="LT"/> </coding> </jurisdiction> <item> <linkId value="grp-referral"/> <text value="Referral to perform pathology test"/> <type value="display"/> </item> <item> <linkId value="grp-patient"/> <text value="Patient information"/> <type value="group"/> <item> <linkId value="patient-personal-code"/> <text value="Personal code"/> <type value="string"/> </item> <item> <linkId value="patient-name"/> <text value="Name"/> <type value="string"/> </item> <item> <linkId value="patient-surname"/> <text value="Surname"/> <type value="string"/> </item> <item> <linkId value="patient-birth-date"/> <text value="Date of birth"/> <type value="date"/> </item> <item> <linkId value="patient-age"/> <text value="Age"/> <type value="integer"/> </item> <item> <linkId value="patient-gender"/> <text value="Gender"/> <type value="coding"/> <answerOption> <valueCoding> <system value="http://hl7.org/fhir/administrative-gender"/> <code value="male"/> <display value="Male"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="http://hl7.org/fhir/administrative-gender"/> <code value="female"/> <display value="Female"/> </valueCoding> </answerOption> </item> </item> <item> <linkId value="grp-specimen-dates"/> <text value="Specimen dates"/> <type value="group"/> <item> <linkId value="specimen-collection-date"/> <text value="Date of material collection"/> <type value="dateTime"/> </item> <item> <linkId value="specimen-shipment-date"/> <text value="Shipment / formation date"/> <type value="dateTime"/> </item> </item> <item> <linkId value="grp-clinical-diagnosis"/> <text value="Clinical diagnosis"/> <type value="group"/> <item> <linkId value="diagnosis-icd10-code"/> <text value="Clinical diagnosis ICD-10-AM code"/> <type value="string"/> </item> <item> <linkId value="diagnosis-name"/> <text value="Clinical diagnosis name"/> <type value="text"/> </item> </item> <item> <linkId value="grp-material"/> <text value="Material fixation"/> <type value="group"/> <item> <linkId value="fixation-type"/> <text value="Material fixation type"/> <type value="coding"/> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="fixation-formalin"/> <display value="Fixed (10% formalin buffered solution)"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="fixation-unfixed"/> <display value="Unfixed"/> </valueCoding> </answerOption> </item> </item> <item> <linkId value="grp-previous-procedures"/> <text value="Previous procedures and key clinical data"/> <type value="group"/> <item> <linkId value="previous-procedures"/> <text value="Key clinical data"/> <type value="coding"/> <repeats value="true"/> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="proc-none"/> <display value="No important information"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="proc-biopsy"/> <display value="Biopsy"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="proc-excision"/> <display value="Excision"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="proc-other-operation"/> <display value="Other operation"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="proc-chemotherapy"/> <display value="Chemotherapy"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="proc-radiation"/> <display value="Radiation (breast)"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="proc-immunotherapy"/> <display value="Immunotherapy"/> </valueCoding> </answerOption> </item> <item> <linkId value="previous-procedures-other"/> <text value="Other information"/> <type value="text"/> </item> </item> <item> <linkId value="grp-special-tests"/> <text value="Special tests"/> <type value="group"/> <item> <linkId value="special-tests-required"/> <text value="Special tests required"/> <type value="text"/> </item> </item> <item> <linkId value="grp-radiological-data"/> <text value="Radiological examination data"/> <type value="group"/> <item> <linkId value="radiology-performed"/> <text value="Radiological examination performed"/> <type value="coding"/> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="yes"/> <display value="Yes"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="no"/> <display value="No"/> </valueCoding> </answerOption> </item> <item> <linkId value="radiology-exam-type"/> <text value="Examination type"/> <type value="coding"/> <repeats value="true"/> <answerOption> <valueCoding> <system value="http://snomed.info/sct"/> <code value="71651007"/> <display value="Mammography"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="http://snomed.info/sct"/> <code value="439324009"/> <display value="Digital breast tomosynthesis"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="http://snomed.info/sct"/> <code value="16310003"/> <display value="Ultrasonography"/> </valueCoding> </answerOption> </item> <item> <linkId value="radiology-exam-date"/> <text value="Examination date"/> <type value="date"/> </item> <item> <linkId value="birads-right"/> <text value="BI-RADS right breast"/> <type value="coding"/> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="birads-0"/> <display value="BI-RADS 0 – Incomplete examination"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="birads-1"/> <display value="BI-RADS 1 – No changes found"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="birads-2"/> <display value="BI-RADS 2 – Benign changes found"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="birads-3"/> <display value="BI-RADS 3 – Possibly benign changes"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="birads-4"/> <display value="BI-RADS 4 – Suspicious malignant finding"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="birads-5"/> <display value="BI-RADS 5 – Highly probable malignant finding"/> </valueCoding> </answerOption> </item> <item> <linkId value="birads-left"/> <text value="BI-RADS left breast"/> <type value="coding"/> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="birads-0"/> <display value="BI-RADS 0 – Incomplete examination"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="birads-1"/> <display value="BI-RADS 1 – No changes found"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="birads-2"/> <display value="BI-RADS 2 – Benign changes found"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="birads-3"/> <display value="BI-RADS 3 – Possibly benign changes"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="birads-4"/> <display value="BI-RADS 4 – Suspicious malignant finding"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="birads-5"/> <display value="BI-RADS 5 – Highly probable malignant finding"/> </valueCoding> </answerOption> </item> </item> <item> <linkId value="grp-operation"/> <text value="Operation details"/> <type value="group"/> <item> <linkId value="operation-nature"/> <text value="Nature of operation"/> <type value="coding"/> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="op-thick-needle-biopsy"/> <display value="Thick needle biopsy"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="op-excision"/> <display value="Excision"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="op-other"/> <display value="Other (free text)"/> </valueCoding> </answerOption> </item> <item> <linkId value="operation-other-details"/> <text value="Other operation details"/> <type value="text"/> </item> </item> <item> <linkId value="grp-histological-sample"/> <text value="Description of histological sample / object"/> <type value="group"/> <item> <linkId value="sample-container-info"/> <text value="Container information"/> <type value="text"/> </item> <item> <linkId value="sample-biopsy-location"/> <text value="Biopsy location"/> <type value="text"/> </item> </item> <item> <linkId value="grp-macroscopic"/> <text value="Description of macroscopic examination"/> <type value="group"/> <item> <linkId value="macro-biopsy-size"/> <text value="Biopsy size (mm)"/> <type value="quantity"/> </item> <item> <linkId value="macro-fragment-details"/> <text value="Fragment details"/> <type value="text"/> </item> <item> <linkId value="macro-notes"/> <text value="Notes"/> <type value="text"/> </item> </item> <item> <linkId value="grp-microscopic"/> <text value="Description of microscopic examination"/> <type value="group"/> <item> <linkId value="microscopic-description"/> <text value="Microscopic examination description"/> <type value="text"/> </item> </item> <item> <linkId value="grp-ihc"/> <text value="Immunohistochemistry (IHC)"/> <type value="group"/> <item> <linkId value="ihc-er-status"/> <text value="Estrogen receptors ER"/> <type value="coding"/> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="ihc-negative"/> <display value="Negative"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="ihc-weak"/> <display value="Weak (+)"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="ihc-moderate"/> <display value="Moderate (++)"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="ihc-strong"/> <display value="Strong (+++)"/> </valueCoding> </answerOption> </item> <item> <linkId value="ihc-er-percent"/> <text value="ER expression in nuclei (%)"/> <type value="quantity"/> </item> <item> <linkId value="ihc-pr-status"/> <text value="Progesterone receptors PR"/> <type value="coding"/> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="ihc-negative"/> <display value="Negative"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="ihc-weak"/> <display value="Weak (+)"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="ihc-moderate"/> <display value="Moderate (++)"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="ihc-strong"/> <display value="Strong (+++)"/> </valueCoding> </answerOption> </item> <item> <linkId value="ihc-pr-percent"/> <text value="PR expression in nuclei (%)"/> <type value="quantity"/> </item> <item> <linkId value="ihc-her2-status"/> <text value="HER2 status"/> <type value="coding"/> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="her2-negative"/> <display value="HER2: expression absent (0)"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="her2-low"/> <display value="HER2: low immunohistochemical expression (1+)"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="her2-borderline"/> <display value="HER2: expression borderline (2+)"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="her2-positive"/> <display value="HER2: expression positive (3+)"/> </valueCoding> </answerOption> </item> <item> <linkId value="ihc-her2-evaluation"/> <text value="HER2 evaluation"/> <type value="coding"/> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="her2-eval-0"/> <display value="HER2 evaluation: 0+"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="her2-eval-1"/> <display value="HER2 evaluation: 1+"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="her2-eval-2"/> <display value="HER2 evaluation: 2+"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="her2-eval-3"/> <display value="HER2 evaluation: 3+"/> </valueCoding> </answerOption> </item> <item> <linkId value="ihc-ki67"/> <text value="Ki67 proliferation index (%)"/> <type value="quantity"/> </item> </item> <item> <linkId value="grp-molecular"/> <text value="Molecular studies"/> <type value="group"/> <item> <linkId value="fish-result"/> <text value="FISH result"/> <type value="coding"/> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="fish-amplified"/> <display value="FISH: HER2 amplified"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="fish-amplified-clusters"/> <display value="FISH: amplified (clusters)"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="fish-co-amplified"/> <display value="FISH: co-amplified (HER2>=6, HER2/CEP17<2)"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="fish-borderline"/> <display value="FISH: borderline (4<=HER2<6, HER2/CEP17<2)"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="fish-monosomic"/> <display value="FISH: monosomic (HER2<4, HER2/CEP17>=2)"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="fish-negative"/> <display value="FISH: negative (HER2<4, HER2/CEP17<2)"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="fish-not-evaluated"/> <display value="FISH: not to be evaluated"/> </valueCoding> </answerOption> </item> <item> <linkId value="fish-her2-average"/> <text value="HER2 average"/> <type value="decimal"/> </item> <item> <linkId value="fish-cep17-average"/> <text value="Average CEP17"/> <type value="decimal"/> </item> <item> <linkId value="fish-her2-cep17-ratio"/> <text value="HER2/CEP17 ratio"/> <type value="decimal"/> </item> <item> <linkId value="cish-sish-result"/> <text value="CISH/SISH result"/> <type value="coding"/> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="cish-amplified"/> <display value="CISH/SISH: HER2 amplified"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="cish-not-amplified"/> <display value="CISH/SISH: HER2 not amplified"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="cish-not-evaluated"/> <display value="CISH/SISH: not to be evaluated"/> </valueCoding> </answerOption> </item> </item> <item> <linkId value="grp-conclusion"/> <text value="Conclusion"/> <type value="group"/> <item> <linkId value="conclusion-who-diagnosis"/> <text value="WHO Classification diagnosis"/> <type value="text"/> </item> <item> <linkId value="conclusion-tumour-grade"/> <text value="Tumour grade"/> <type value="coding"/> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="grade-g1"/> <display value="G1 (well-differentiated)"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="grade-g2"/> <display value="G2 (moderately differentiated)"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="grade-g3"/> <display value="G3 (poorly differentiated)"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="grade-gx"/> <display value="Gx (degree of differentiation undetermined)"/> </valueCoding> </answerOption> </item> <item> <linkId value="conclusion-tumour-size"/> <text value="Tumour size (mm)"/> <type value="quantity"/> </item> <item> <linkId value="conclusion-lvi"/> <text value="Lymphovascular invasion"/> <type value="coding"/> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="lvi-0"/> <display value="pLVI-0: not detected"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="lvi-1"/> <display value="pLVI-1: spreading, otherwise unclassified"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="lvi-2"/> <display value="pLVI-2: only in lymphatic vessels and small blood vessels"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="lvi-3"/> <display value="pLVI-3: only in veins (large, thick-walled blood vessels)"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="lvi-4"/> <display value="pLVI-4: present in both lymphatic vessels and veins"/> </valueCoding> </answerOption> <answerOption> <valueCoding> <system value="https://tx.hl7.lt/fhir/CodeSystem/breast-questionnaire-options"/> <code value="lvi-9"/> <display value="pLVI-9: undetectable/unknown"/> </valueCoding> </answerOption> </item> </item> </Questionnaire>