#1

GET https://tx.fhir.org/r5/metadata HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
User-Agent: fhir/publisher

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:4214
content-type:application/fhir+json
date:Thu, 31 Jul 2025 20:40:00 GMT
pragma:no-cache
server:nginx
x-request-id:233-7001417

{"resourceType" : "CapabilityStatement","id" : "FhirServer","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><h2>Local User Conformance Statement</h2><p>FHIR v5.0.0 released 20250710140439.594Z. Server version 3.7.24 built 20250710140439.594Z</p><table class=\"grid\"><tr><th>Resource Type</th><th>Profile</th><th>Read</th><th>V-Read</th><th>Search</th><th>Update</th><th>Updates</th><th>Create</th><th>Delete</th><th>History</th></tr>\n</table>\n<p>Operations</p>\n<ul>\n <li>expand: see OperationDefinition/fso-expand</li>\n <li>lookup: see OperationDefinition/fso-lookup</li>\n <li>validate-code: see OperationDefinition/fso-validate-code</li>\n <li>batch-validate-code: see OperationDefinition/fso-batch-validate-code</li>\n <li>translate: see OperationDefinition/fso-translate</li>\n <li>closure: see OperationDefinition/fso-closure</li>\n <li>versions: see OperationDefinition/fso-versions</li>\n</ul>\n</div>"},"extension" : [{"extension" : [{"url" : "definition","valueCanonical" : "http://hl7.org/fhir/uv/tx-tests/FeatureDefinition/test-version"},{"url" : "value","valueCode" : "1.7.8"},{"extension" : [{"url" : "name","valueCode" : "mode"},{"url" : "value","valueCode" : "tx.fhir.org"}],"url" : "qualifier"}],"url" : "http://hl7.org/fhir/uv/application-feature/StructureDefinition/feature"},{"extension" : [{"url" : "definition","valueCanonical" : "http://hl7.org/fhir/uv/tx-ecosystem/FeatureDefinition/CodeSystemAsParameter"},{"url" : "value","valueBoolean" : true}],"url" : "http://hl7.org/fhir/uv/application-feature/StructureDefinition/feature"}],"url" : "http://tx.fhir.org/r5/CapabilityStatement/tx","version" : "5.0.0-3.7.24","name" : "FHIRReferenceServer","title" : "FHIR Reference Server Conformance Statement","status" : "active","date" : "2025-07-31T20:40:00.429Z","contact" : [{"telecom" : [{"system" : "other","value" : "http://healthintersections.com.au/"}]}],"description" : "Standard Conformance Statement for the open source Reference FHIR Server provided by Health Intersections","kind" : "instance","instantiates" : ["http://hl7.org/fhir/CapabilityStatement/terminology-server","http://hl7.org/fhir/CapabilityStatement/terminology-server"],"software" : {"name" : "Reference Server","version" : "3.7.24","releaseDate" : "2025-07-10T14:04:39.594Z"},"implementation" : {"description" : "FHIR Server running at http://tx.fhir.org/r5","url" : "http://tx.fhir.org/r5"},"fhirVersion" : "5.0.0","format" : ["application/fhir+xml","application/fhir+json"],"rest" : [{"mode" : "server","security" : {"cors" : true},"resource" : [{"type" : "CodeSystem","interaction" : [{"code" : "read","documentation" : "Read a code system"},{"code" : "search-type","documentation" : "Search the code systems. Not that there a few major code systems that are not available through this API (SCT, LOINC etc)"}],"operation" : [{"name" : "validate-code","definition" : "http://hl7.org/fhir/OperationDefinition/CodeSystem-validate-code"},{"name" : "lookup","definition" : "http://hl7.org/fhir/OperationDefinition/CodeSystem-lookup"}]},{"type" : "ValueSet","interaction" : [{"code" : "read","documentation" : "Read a ValueSet"},{"code" : "search-type","documentation" : "Search the value sets"}],"operation" : [{"name" : "validate-code","definition" : "http://hl7.org/fhir/OperationDefinition/ValueSet-validate-code"},{"name" : "expand","definition" : "http://hl7.org/fhir/OperationDefinition/ValueSet-expand"}]}],"interaction" : [{"code" : "transaction"}],"operation" : [{"name" : "expand","definition" : "http://hl7.org/fhir/OperationDefinition/ValueSet-expand"},{"name" : "lookup","definition" : "http://hl7.org/fhir/OperationDefinition/ValueSet-lookup"},{"name" : "validate-code","definition" : "http://hl7.org/fhir/OperationDefinition/Resource-validate-code"},{"name" : "batch-validate-code","definition" : "http://hl7.org/fhir/OperationDefinition/Resource-batch-validate-code"},{"name" : "translate","definition" : "http://hl7.org/fhir/OperationDefinition/ConceptMap-translate"},{"name" : "closure","definition" : "http://hl7.org/fhir/OperationDefinition/ConceptMap-closure"},{"name" : "versions","definition" : "http://tx.fhir.org/r5/OperationDefinition/fso-versions"}]}]}

#2

GET https://tx.fhir.org/r5/metadata?mode=terminology HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
User-Agent: fhir/publisher

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
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access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:133193
content-type:application/fhir+json
date:Thu, 31 Jul 2025 20:40:00 GMT
pragma:no-cache
server:nginx
x-request-id:233-7001420

{"resourceType" : "TerminologyCapabilities","id" : "FhirServer","url" : "http://tx.fhir.org/r5/TerminologyCapabilities/tx","version" : "2.0.0","name" : "FHIRReferenceServerTerminologyCapabilities","title" : "FHIR Reference Server Terminology Capability Statement","status" : "active","date" : "2025-07-31T20:40:00.604Z","contact" : [{"telecom" : [{"system" : "other","value" : "http://healthintersections.com.au/"}]}],"description" : "Standard Terminology Capability Statement for the open source Reference FHIR Server provided by Health Intersections","codeSystem" : [{"uri" : "http://cap.org/eCP","version" : [{"code" : "4.000.001"}]},{"uri" : "http://cds-hooks.hl7.org/CodeSystem/indicator","version" : [{"code" : "5.0.0"}]},{"uri" : "http://devices.fhir.org/CodeSystem/MDC-concept-status"},{"uri" : "http://devices.fhir.org/CodeSystem/MDC-designation-use"},{"uri" : "http://dicom.nema.org/resources/ontology/DCM","version" : [{"code" : "2025.2.20250411"}]},{"uri" : "http://fdasis.nlm.nih.gov","version" : [{"code" : "2024-06-22"}]},{"uri" : "http://healthit.gov/nhin/purposeofuse","version" : [{"code" : "2.0"}]},{"uri" : "http://hl7.org/fhir/account-aggregate","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/account-balance-term","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/account-billing-status","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/account-relationship","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/account-status","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/action-cardinality-behavior","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/action-code","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/action-condition-kind","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/action-grouping-behavior","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/action-participant-function","version" : [{"code" : 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"2018"}]},{"uri" : "urn:iso:std:iso:3166","version" : [{"code" : "20210120"}]},{"uri" : "urn:iso:std:iso:4217"},{"uri" : "urn:iso-astm:E1762-95:2013","version" : [{"code" : "5.0.0"}]},{"uri" : "urn:oid:1.2.36.1.2001.1001.101.104.16592","version" : [{"code" : "5.0.0"}]},{"uri" : "urn:oid:1.2.36.1.2001.1005.17"},{"uri" : "urn:oid:2.16.840.1.113883.2.9.6.2.7","version" : [{"code" : "ISCO-08"}]},{"uri" : "urn:oid:2.16.840.1.113883.3.1937.98.5.8"},{"uri" : "urn:oid:2.16.840.1.113883.3.1937.98.5.8","version" : [{"code" : "5.0.0"}]}],"expansion" : {"parameter" : [{"name" : "cache-id","documentation" : "This server supports caching terminology resources between calls. Clients only need to send value sets and codesystems once; there after they are automatically in scope for calls with the same cache-id. The cache is retained for 30 min from last call"},{"name" : "tx-resource","documentation" : "Additional valuesets needed for evaluation e.g. value sets referred to from the import statement of the value set being expanded"},{"name" : "_incomplete"},{"name" : "abstract"},{"name" : "activeOnly"},{"name" : "check-system-version"},{"name" : "count"},{"name" : "default-to-latest-version"},{"name" : "displayLanguage"},{"name" : "excludeNested"},{"name" : "excludeNotForUI"},{"name" : "excludePostCoordinated"},{"name" : "force-system-version"},{"name" : "inactive"},{"name" : "includeAlternateCodes"},{"name" : "includeDefinition"},{"name" : "includeDesignations"},{"name" : "incomplete-ok"},{"name" : "limitedExpansion"},{"name" : "mode","documentation" : "=lenient-display-validation"},{"name" : "no-cache"},{"name" : "offset"},{"name" : "profile"},{"name" : "property"},{"name" : "system-version"},{"name" : "valueSetMode","documentation" : "= CHECK_MEMBERSHIP_ONLY | NO_MEMBERSHIP_CHECK"}]}}

#3

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C97054"}},{"name":"displayLanguage","valueCode":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"965d12b7-26e5-4742-8287-b739fab0f666"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:908
content-type:application/fhir+json
date:Thu, 31 Jul 2025 20:40:19 GMT
last-modified:Thu, 31 Jul 2025 20:40:19 GMT
pragma:no-cache
server:nginx
x-request-id:233-7001585

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C97054"},{"name" : "display","valueString" : "Generic Name"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C97054 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C97054\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl| (from fhir.tx.support.r4#0.30.0)\" (content = fragment)\r\n"}]}

#4

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C71898"}},{"name":"displayLanguage","valueCode":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"965d12b7-26e5-4742-8287-b739fab0f666"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:912
content-type:application/fhir+json
date:Thu, 31 Jul 2025 20:40:19 GMT
last-modified:Thu, 31 Jul 2025 20:40:19 GMT
pragma:no-cache
server:nginx
x-request-id:233-7001587

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C71898"},{"name" : "display","valueString" : "Proprietary Name"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C71898 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C71898\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl| (from fhir.tx.support.r4#0.30.0)\" (content = fragment)\r\n"}]}

#5

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":true},{"name":"cache-id","valueId":"965d12b7-26e5-4742-8287-b739fab0f666"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":false,"include":[{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","concept":[{"code":"C49487","display":"No"},{"code":"C48660","display":"Not Applicable"},{"code":"C17998","display":"Unknown"},{"code":"C49488","display":"Yes"}]}]}}}]}

422
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
connection:keep-alive
content-length:627
content-type:application/fhir+json
date:Thu, 31 Jul 2025 20:40:21 GMT
server:nginx
x-request-id:233-7001590

{"resourceType" : "OperationOutcome","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>The code system definition for http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl is a fragment, so this expansion is not permitted unless the expansion parameter \"incomplete-ok\" has a value of \"true\"</p></div>"},"issue" : [{"severity" : "error","code" : "invalid","details" : {"text" : "The code system definition for http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl is a fragment, so this expansion is not permitted unless the expansion parameter \"incomplete-ok\" has a value of \"true\""}}]}

#6

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"_limit","valueInteger":10000},{"name":"_incomplete","valueBoolean":true},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"excludeNested","valueBoolean":true},{"name":"cache-id","valueId":"965d12b7-26e5-4742-8287-b739fab0f666"},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/cdisc-yes-no-vs-inc-0","status":"active","compose":{"inactive":false,"include":[{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","concept":[{"code":"C49487","display":"No"},{"code":"C48660","display":"Not Applicable"},{"code":"C17998","display":"Unknown"},{"code":"C49488","display":"Yes"}]}]}}}]}

422
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
connection:keep-alive
content-length:627
content-type:application/fhir+json
date:Thu, 31 Jul 2025 20:40:21 GMT
server:nginx
x-request-id:233-7001593

{"resourceType" : "OperationOutcome","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>The code system definition for http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl is a fragment, so this expansion is not permitted unless the expansion parameter \"incomplete-ok\" has a value of \"true\"</p></div>"},"issue" : [{"severity" : "error","code" : "invalid","details" : {"text" : "The code system definition for http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl is a fragment, so this expansion is not permitted unless the expansion parameter \"incomplete-ok\" has a value of \"true\""}}]}

#7

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":true},{"name":"cache-id","valueId":"965d12b7-26e5-4742-8287-b739fab0f666"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":false,"include":[{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","concept":[{"code":"C207615","display":"Brief Study Title"},{"code":"C207646","display":"Study Acronym"}]}]}}}]}

422
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
connection:keep-alive
content-length:627
content-type:application/fhir+json
date:Thu, 31 Jul 2025 20:40:21 GMT
server:nginx
x-request-id:233-7001596

{"resourceType" : "OperationOutcome","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>The code system definition for http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl is a fragment, so this expansion is not permitted unless the expansion parameter \"incomplete-ok\" has a value of \"true\"</p></div>"},"issue" : [{"severity" : "error","code" : "invalid","details" : {"text" : "The code system definition for http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl is a fragment, so this expansion is not permitted unless the expansion parameter \"incomplete-ok\" has a value of \"true\""}}]}

#8

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"_limit","valueInteger":10000},{"name":"_incomplete","valueBoolean":true},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"excludeNested","valueBoolean":true},{"name":"cache-id","valueId":"965d12b7-26e5-4742-8287-b739fab0f666"},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/ddf-study-title-type-vs-inc-0","status":"active","compose":{"inactive":false,"include":[{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","concept":[{"code":"C207615","display":"Brief Study Title"},{"code":"C207646","display":"Study Acronym"}]}]}}}]}

422
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
connection:keep-alive
content-length:627
content-type:application/fhir+json
date:Thu, 31 Jul 2025 20:40:21 GMT
server:nginx
x-request-id:233-7001599

{"resourceType" : "OperationOutcome","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>The code system definition for http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl is a fragment, so this expansion is not permitted unless the expansion parameter \"incomplete-ok\" has a value of \"true\"</p></div>"},"issue" : [{"severity" : "error","code" : "invalid","details" : {"text" : "The code system definition for http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl is a fragment, so this expansion is not permitted unless the expansion parameter \"incomplete-ok\" has a value of \"true\""}}]}

#9

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":true},{"name":"cache-id","valueId":"965d12b7-26e5-4742-8287-b739fab0f666"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":false,"include":[{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","concept":[{"code":"C68846","display":"Globally"},{"code":"C41065","display":"Locally"},{"code":"C218489","display":"By Cohort"}]}]}}}]}

422
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
connection:keep-alive
content-length:627
content-type:application/fhir+json
date:Thu, 31 Jul 2025 20:40:21 GMT
server:nginx
x-request-id:233-7001602

{"resourceType" : "OperationOutcome","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>The code system definition for http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl is a fragment, so this expansion is not permitted unless the expansion parameter \"incomplete-ok\" has a value of \"true\"</p></div>"},"issue" : [{"severity" : "error","code" : "invalid","details" : {"text" : "The code system definition for http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl is a fragment, so this expansion is not permitted unless the expansion parameter \"incomplete-ok\" has a value of \"true\""}}]}

#10

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"_limit","valueInteger":10000},{"name":"_incomplete","valueBoolean":true},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"excludeNested","valueBoolean":true},{"name":"cache-id","valueId":"965d12b7-26e5-4742-8287-b739fab0f666"},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-amendment-scope-enrollment-vs-inc-0","status":"active","compose":{"inactive":false,"include":[{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","concept":[{"code":"C68846","display":"Globally"},{"code":"C41065","display":"Locally"},{"code":"C218489","display":"By Cohort"}]}]}}}]}

422
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
connection:keep-alive
content-length:627
content-type:application/fhir+json
date:Thu, 31 Jul 2025 20:40:21 GMT
server:nginx
x-request-id:233-7001605

{"resourceType" : "OperationOutcome","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>The code system definition for http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl is a fragment, so this expansion is not permitted unless the expansion parameter \"incomplete-ok\" has a value of \"true\"</p></div>"},"issue" : [{"severity" : "error","code" : "invalid","details" : {"text" : "The code system definition for http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl is a fragment, so this expansion is not permitted unless the expansion parameter \"incomplete-ok\" has a value of \"true\""}}]}

#11

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":true},{"name":"cache-id","valueId":"965d12b7-26e5-4742-8287-b739fab0f666"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":false,"include":[{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","concept":[{"code":"C132351","display":"Sponsor Protocol Identifier"},{"code":"C218672","display":"Original Protocol Indicator"},{"code":"C218477","display":"Amendment Identifier"},{"code":"C218684","display":"EU CT Number"},{"code":"C218685","display":"FDA IND Number"},{"code":"C218686","display":"IDE Number"},{"code":"C218687","display":"jRCT Number"},{"code":"C172240","display":"NCT Number"},{"code":"C218688","display":"NMPA IND Number"},{"code":"C218689","display":"WHO/UTN Number"},{"code":"C218690","display":"Other Regulatory or Clinical Trial Identifier"}]}]}}}]}

422
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
connection:keep-alive
content-length:627
content-type:application/fhir+json
date:Thu, 31 Jul 2025 20:40:21 GMT
server:nginx
x-request-id:233-7001608

{"resourceType" : "OperationOutcome","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>The code system definition for http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl is a fragment, so this expansion is not permitted unless the expansion parameter \"incomplete-ok\" has a value of \"true\"</p></div>"},"issue" : [{"severity" : "error","code" : "invalid","details" : {"text" : "The code system definition for http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl is a fragment, so this expansion is not permitted unless the expansion parameter \"incomplete-ok\" has a value of \"true\""}}]}

#12

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
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#13

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#14

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#15

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#16

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422
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date:Thu, 31 Jul 2025 20:40:22 GMT
server:nginx
x-request-id:233-7001623

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#17

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
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422
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date:Thu, 31 Jul 2025 20:40:22 GMT
server:nginx
x-request-id:233-7001626

{"resourceType" : "OperationOutcome","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>The code system definition for http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl is a fragment, so this expansion is not permitted unless the expansion parameter \"incomplete-ok\" has a value of \"true\"</p></div>"},"issue" : [{"severity" : "error","code" : "invalid","details" : {"text" : "The code system definition for http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl is a fragment, so this expansion is not permitted unless the expansion parameter \"incomplete-ok\" has a value of \"true\""}}]}

#18

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
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422
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server:nginx
x-request-id:233-7001629

{"resourceType" : "OperationOutcome","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>The code system definition for http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl is a fragment, so this expansion is not permitted unless the expansion parameter \"incomplete-ok\" has a value of \"true\"</p></div>"},"issue" : [{"severity" : "error","code" : "invalid","details" : {"text" : "The code system definition for http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl is a fragment, so this expansion is not permitted unless the expansion parameter \"incomplete-ok\" has a value of \"true\""}}]}

#19

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
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422
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server:nginx
x-request-id:233-7001632

{"resourceType" : "OperationOutcome","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>The code system definition for http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl is a fragment, so this expansion is not permitted unless the expansion parameter \"incomplete-ok\" has a value of \"true\"</p></div>"},"issue" : [{"severity" : "error","code" : "invalid","details" : {"text" : "The code system definition for http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl is a fragment, so this expansion is not permitted unless the expansion parameter \"incomplete-ok\" has a value of \"true\""}}]}

#20

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
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date:Thu, 31 Jul 2025 20:40:22 GMT
server:nginx
x-request-id:233-7001635

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#21

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
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{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":true},{"name":"cache-id","valueId":"965d12b7-26e5-4742-8287-b739fab0f666"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":false,"include":[{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","concept":[{"code":"C70793","display":"Clinical Study Sponsor"},{"code":"C215670","display":"Local Legal Sponsor"},{"code":"C215669","display":"Study Co-Sponsor"},{"code":"C93478","display":"Study Legal Sponsor"}]}]}}}]}

422
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date:Thu, 31 Jul 2025 20:40:23 GMT
server:nginx
x-request-id:233-7001640

{"resourceType" : "OperationOutcome","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>The code system definition for http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl is a fragment, so this expansion is not permitted unless the expansion parameter \"incomplete-ok\" has a value of \"true\"</p></div>"},"issue" : [{"severity" : "error","code" : "invalid","details" : {"text" : "The code system definition for http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl is a fragment, so this expansion is not permitted unless the expansion parameter \"incomplete-ok\" has a value of \"true\""}}]}

#22

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"_limit","valueInteger":10000},{"name":"_incomplete","valueBoolean":true},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"excludeNested","valueBoolean":true},{"name":"cache-id","valueId":"965d12b7-26e5-4742-8287-b739fab0f666"},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/nci-study-role-vs-inc-0","status":"active","compose":{"inactive":false,"include":[{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","concept":[{"code":"C70793","display":"Clinical Study Sponsor"},{"code":"C215670","display":"Local Legal Sponsor"},{"code":"C215669","display":"Study Co-Sponsor"},{"code":"C93478","display":"Study Legal Sponsor"}]}]}}}]}

422
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server:nginx
x-request-id:233-7001646

{"resourceType" : "OperationOutcome","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>The code system definition for http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl is a fragment, so this expansion is not permitted unless the expansion parameter \"incomplete-ok\" has a value of \"true\"</p></div>"},"issue" : [{"severity" : "error","code" : "invalid","details" : {"text" : "The code system definition for http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl is a fragment, so this expansion is not permitted unless the expansion parameter \"incomplete-ok\" has a value of \"true\""}}]}

#23

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
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{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}},{"name":"displayLanguage","valueCode":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"jurisdiction","meta":{"lastUpdated":"2025-04-01T12:16:37.966+11:00","profile":["http://hl7.org/fhir/StructureDefinition/shareablevalueset"]},"text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"vocab"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"deprecated"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":5}],"url":"http://hl7.org/fhir/ValueSet/jurisdiction","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.48"}],"version":"6.0.0-ballot3","name":"JurisdictionValueSet","title":"Jurisdiction ValueSet","status":"draft","experimental":false,"date":"2025-04-01T12:16:37+11:00","publisher":"HL7 International / Terminology Infrastructure","contact":[{"telecom":[{"system":"url","value":"http://hl7.org/fhir"}]},{"telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/Vocab"}]}],"description":"This value set defines a base set of codes for country, country subdivision and region    for indicating where a resource is intended to be used.   \r\n   \r\n   Note: The codes for countries and country subdivisions are taken from    [ISO 3166](https://www.iso.org/iso-3166-country-codes.html)    while the codes for \"supra-national\" regions are from    [UN Standard country or area codes for statistical use (M49)](http://unstats.un.org/unsd/methods/m49/m49.htm).","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"compose":{"include":[{"system":"urn:iso:std:iso:3166"},{"system":"urn:iso:std:iso:3166:-2"},{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","filter":[{"property":"class","op":"=","value":"region"}]}]}}},{"name":"cache-id","valueId":"965d12b7-26e5-4742-8287-b739fab0f666"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2227
content-type:application/fhir+json
date:Thu, 31 Jul 2025 20:40:23 GMT
last-modified:Thu, 31 Jul 2025 20:40:23 GMT
pragma:no-cache
server:nginx
x-request-id:233-7001653

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://unstats.un.org/unsd/methods/m49/m49.htm"},{"name" : "code","valueCode" : "001"},{"name" : "display","valueString" : "World"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://unstats.un.org/unsd/methods/m49/m49.htm","code" : "001","display" : "World"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "MSG_DEPRECATED"}],"severity" : "information","code" : "business-rule","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "status-check"}],"text" : "Reference to deprecated ValueSet http://hl7.org/fhir/ValueSet/jurisdiction|6.0.0-ballot3"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/jurisdiction|6.0.0-ballot3: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/jurisdiction|6.0.0-ballot3: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/jurisdiction|6.0.0-ballot3: CodeSystem found: \"urn:iso:std:iso:3166|2018\"\r\n32 16: 16ms http://hl7.org/fhir/ValueSet/jurisdiction|6.0.0-ballot3: CodeSystem found: \"urn:iso:std:iso:3166:-2|2021 (from fhir.tx.support.r4#0.30.0)\"\r\n32 0: 16ms http://hl7.org/fhir/ValueSet/jurisdiction|6.0.0-ballot3: CodeSystem found: \"http://unstats.un.org/unsd/methods/m49/m49.htm|\"\r\n32 0: 16ms http://hl7.org/fhir/ValueSet/jurisdiction|6.0.0-ballot3: Validate \"[http://unstats.un.org/unsd/methods/m49/m49.htm#001 (\"World\")]\"\r\n32 0: 16ms http://hl7.org/fhir/ValueSet/jurisdiction|6.0.0-ballot3: Check \"http://unstats.un.org/unsd/methods/m49/m49.htm#001\"\r\n32 0: 16ms http://hl7.org/fhir/ValueSet/jurisdiction|6.0.0-ballot3: CodeSystem found: http://unstats.un.org/unsd/methods/m49/m49.htm| for http://unstats.un.org/unsd/methods/m49/m49.htm\r\n32 0: 16ms http://hl7.org/fhir/ValueSet/jurisdiction|6.0.0-ballot3: Filter \"class = region\": Code \"001\" found in http://unstats.un.org/unsd/methods/m49/m49.htm|\r\n"}]}

#24

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C49487"}},{"name":"displayLanguage","valueCode":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"965d12b7-26e5-4742-8287-b739fab0f666"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1766
content-type:application/fhir+json
date:Thu, 31 Jul 2025 20:40:23 GMT
last-modified:Thu, 31 Jul 2025 20:40:23 GMT
pragma:no-cache
server:nginx
x-request-id:233-7001656

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C49487"},{"name" : "message","valueString" : "Unknown Code 'C49487' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C49487' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C49487 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C49487\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl| (from fhir.tx.support.r4#0.30.0)\" (content = fragment)\r\n"}]}

#25

POST https://tx.fhir.org/r5/ValueSet/$batch-validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C48660"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C17998"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C49488"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}}]}

200
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access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
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content-type:application/fhir+json
date:Thu, 31 Jul 2025 20:40:23 GMT
last-modified:Thu, 31 Jul 2025 20:40:23 GMT
pragma:no-cache
server:nginx
x-request-id:233-7001658

{"resourceType" : "Parameters","parameter" : [{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C48660"},{"name" : "display","valueString" : "Not Applicable"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C17998"},{"name" : "display","valueString" : "Unknown"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C49488"},{"name" : "message","valueString" : "Unknown Code 'C49488' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C49488' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}}]}}]}

#26

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C207615"}},{"name":"displayLanguage","valueCode":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"965d12b7-26e5-4742-8287-b739fab0f666"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1778
content-type:application/fhir+json
date:Thu, 31 Jul 2025 20:40:23 GMT
last-modified:Thu, 31 Jul 2025 20:40:23 GMT
pragma:no-cache
server:nginx
x-request-id:233-7001660

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C207615"},{"name" : "message","valueString" : "Unknown Code 'C207615' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C207615' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C207615 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C207615\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl| (from fhir.tx.support.r4#0.30.0)\" (content = fragment)\r\n"}]}

#27

POST https://tx.fhir.org/r5/ValueSet/$batch-validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C207646"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1214
content-type:application/fhir+json
date:Thu, 31 Jul 2025 20:40:24 GMT
last-modified:Thu, 31 Jul 2025 20:40:24 GMT
pragma:no-cache
server:nginx
x-request-id:233-7001665

{"resourceType" : "Parameters","parameter" : [{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C207646"},{"name" : "message","valueString" : "Unknown Code 'C207646' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C207646' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}}]}}]}

#28

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C68846"}},{"name":"displayLanguage","valueCode":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"965d12b7-26e5-4742-8287-b739fab0f666"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
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content-type:application/fhir+json
date:Thu, 31 Jul 2025 20:40:24 GMT
last-modified:Thu, 31 Jul 2025 20:40:24 GMT
pragma:no-cache
server:nginx
x-request-id:233-7001671

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C68846"},{"name" : "message","valueString" : "Unknown Code 'C68846' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C68846' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C68846 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C68846\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl| (from fhir.tx.support.r4#0.30.0)\" (content = fragment)\r\n"}]}

#29

POST https://tx.fhir.org/r5/ValueSet/$batch-validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C41065"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C218489"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
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content-type:application/fhir+json
date:Thu, 31 Jul 2025 20:40:24 GMT
last-modified:Thu, 31 Jul 2025 20:40:24 GMT
pragma:no-cache
server:nginx
x-request-id:233-7001674

{"resourceType" : "Parameters","parameter" : [{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C41065"},{"name" : "message","valueString" : "Unknown Code 'C41065' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C41065' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C218489"},{"name" : "message","valueString" : "Unknown Code 'C218489' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C218489' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}}]}}]}

#30

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C132351"}},{"name":"displayLanguage","valueCode":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"965d12b7-26e5-4742-8287-b739fab0f666"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1774
content-type:application/fhir+json
date:Thu, 31 Jul 2025 20:40:24 GMT
last-modified:Thu, 31 Jul 2025 20:40:24 GMT
pragma:no-cache
server:nginx
x-request-id:233-7001679

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C132351"},{"name" : "message","valueString" : "Unknown Code 'C132351' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C132351' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C132351 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C132351\"\r\n15 15: 15ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl| (from fhir.tx.support.r4#0.30.0)\" (content = fragment)\r\n"}]}

#31

POST https://tx.fhir.org/r5/ValueSet/$batch-validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C218672"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C218477"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C218684"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C218685"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C218686"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C218687"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C172240"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C218688"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C218689"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C218690"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:11717
content-type:application/fhir+json
date:Thu, 31 Jul 2025 20:40:24 GMT
last-modified:Thu, 31 Jul 2025 20:40:24 GMT
pragma:no-cache
server:nginx
x-request-id:233-7001682

{"resourceType" : "Parameters","parameter" : [{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C218672"},{"name" : "message","valueString" : "Unknown Code 'C218672' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C218672' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C218477"},{"name" : "message","valueString" : "Unknown Code 'C218477' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C218477' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C218684"},{"name" : "message","valueString" : "Unknown Code 'C218684' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C218684' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C218685"},{"name" : "message","valueString" : "Unknown Code 'C218685' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C218685' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C218686"},{"name" : "message","valueString" : "Unknown Code 'C218686' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C218686' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C218687"},{"name" : "message","valueString" : "Unknown Code 'C218687' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C218687' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C172240"},{"name" : "message","valueString" : "Unknown Code 'C172240' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C172240' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C218688"},{"name" : "message","valueString" : "Unknown Code 'C218688' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C218688' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C218689"},{"name" : "message","valueString" : "Unknown Code 'C218689' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C218689' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C218690"},{"name" : "message","valueString" : "Unknown Code 'C218690' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C218690' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}}]}}]}

#32

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C54721"}},{"name":"displayLanguage","valueCode":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"965d12b7-26e5-4742-8287-b739fab0f666"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1773
content-type:application/fhir+json
date:Thu, 31 Jul 2025 20:40:24 GMT
last-modified:Thu, 31 Jul 2025 20:40:24 GMT
pragma:no-cache
server:nginx
x-request-id:233-7001689

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C54721"},{"name" : "message","valueString" : "Unknown Code 'C54721' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C54721' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C54721 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C54721\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl| (from fhir.tx.support.r4#0.30.0)\" (content = fragment)\r\n"}]}

#33

POST https://tx.fhir.org/r5/ValueSet/$batch-validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C15600"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C15693"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C198366"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C198367"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C217024"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C15601"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C15694"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C217025"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C15602"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C15603"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:11699
content-type:application/fhir+json
date:Thu, 31 Jul 2025 20:40:24 GMT
last-modified:Thu, 31 Jul 2025 20:40:24 GMT
pragma:no-cache
server:nginx
x-request-id:233-7001693

{"resourceType" : "Parameters","parameter" : [{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C15600"},{"name" : "message","valueString" : "Unknown Code 'C15600' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C15600' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C15693"},{"name" : "message","valueString" : "Unknown Code 'C15693' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C15693' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C198366"},{"name" : "message","valueString" : "Unknown Code 'C198366' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C198366' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C198367"},{"name" : "message","valueString" : "Unknown Code 'C198367' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C198367' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C217024"},{"name" : "message","valueString" : "Unknown Code 'C217024' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C217024' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C15601"},{"name" : "message","valueString" : "Unknown Code 'C15601' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C15601' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C15694"},{"name" : "message","valueString" : "Unknown Code 'C15694' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C15694' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C217025"},{"name" : "message","valueString" : "Unknown Code 'C217025' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C217025' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C15602"},{"name" : "message","valueString" : "Unknown Code 'C15602' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C15602' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C15603"},{"name" : "message","valueString" : "Unknown Code 'C15603' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C15603' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}}]}}]}

#34

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C218514"}},{"name":"displayLanguage","valueCode":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"965d12b7-26e5-4742-8287-b739fab0f666"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1771
content-type:application/fhir+json
date:Thu, 31 Jul 2025 20:40:25 GMT
last-modified:Thu, 31 Jul 2025 20:40:25 GMT
pragma:no-cache
server:nginx
x-request-id:233-7001699

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C218514"},{"name" : "message","valueString" : "Unknown Code 'C218514' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C218514' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C218514 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C218514\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl| (from fhir.tx.support.r4#0.30.0)\" (content = fragment)\r\n"}]}

#35

POST https://tx.fhir.org/r5/ValueSet/$batch-validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

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note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C218661"},{"name" : "message","valueString" : "Unknown Code 'C218661' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C218661' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - 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note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C218663"},{"name" : "message","valueString" : "Unknown Code 'C218663' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C218663' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C218664"},{"name" : "message","valueString" : "Unknown Code 'C218664' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C218664' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C218665"},{"name" : "message","valueString" : "Unknown Code 'C218665' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C218665' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C218666"},{"name" : "message","valueString" : "Unknown Code 'C218666' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C218666' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C218667"},{"name" : "message","valueString" : "Unknown Code 'C218667' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C218667' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C218668"},{"name" : "message","valueString" : "Unknown Code 'C218668' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C218668' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C218669"},{"name" : "message","valueString" : "Unknown Code 'C218669' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C218669' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C218670"},{"name" : "message","valueString" : "Unknown Code 'C218670' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C218670' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C218671"},{"name" : "message","valueString" : "Unknown Code 'C218671' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C218671' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}}]}}]}

#36

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C218490"}},{"name":"displayLanguage","valueCode":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"965d12b7-26e5-4742-8287-b739fab0f666"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1771
content-type:application/fhir+json
date:Thu, 31 Jul 2025 20:40:27 GMT
last-modified:Thu, 31 Jul 2025 20:40:27 GMT
pragma:no-cache
server:nginx
x-request-id:233-7001745

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C218490"},{"name" : "message","valueString" : "Unknown Code 'C218490' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C218490' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C218490 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C218490\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl| (from fhir.tx.support.r4#0.30.0)\" (content = fragment)\r\n"}]}

#37

POST https://tx.fhir.org/r5/ValueSet/$batch-validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C218491"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C218492"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C218493"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C218494"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C218495"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C218496"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C218497"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C218498"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C218499"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C218500"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C218501"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C218502"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C17649"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:15215
content-type:application/fhir+json
date:Thu, 31 Jul 2025 20:40:27 GMT
last-modified:Thu, 31 Jul 2025 20:40:27 GMT
pragma:no-cache
server:nginx
x-request-id:233-7001747

{"resourceType" : "Parameters","parameter" : [{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C218491"},{"name" : "message","valueString" : "Unknown Code 'C218491' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C218491' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C218492"},{"name" : "message","valueString" : "Unknown Code 'C218492' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C218492' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C218493"},{"name" : "message","valueString" : "Unknown Code 'C218493' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C218493' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C218494"},{"name" : "message","valueString" : "Unknown Code 'C218494' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C218494' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C218495"},{"name" : "message","valueString" : "Unknown Code 'C218495' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C218495' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C218496"},{"name" : "message","valueString" : "Unknown Code 'C218496' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C218496' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C218497"},{"name" : "message","valueString" : "Unknown Code 'C218497' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C218497' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C218498"},{"name" : "message","valueString" : "Unknown Code 'C218498' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C218498' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C218499"},{"name" : "message","valueString" : "Unknown Code 'C218499' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C218499' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C218500"},{"name" : "message","valueString" : "Unknown Code 'C218500' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C218500' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C218501"},{"name" : "message","valueString" : "Unknown Code 'C218501' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C218501' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C218502"},{"name" : "message","valueString" : "Unknown Code 'C218502' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C218502' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C17649"},{"name" : "message","valueString" : "Unknown Code 'C17649' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C17649' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}}]}}]}

#38

POST https://tx.fhir.org/r5/ValueSet/$batch-validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C217026"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1214
content-type:application/fhir+json
date:Thu, 31 Jul 2025 20:40:28 GMT
last-modified:Thu, 31 Jul 2025 20:40:28 GMT
pragma:no-cache
server:nginx
x-request-id:233-7001756

{"resourceType" : "Parameters","parameter" : [{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C217026"},{"name" : "message","valueString" : "Unknown Code 'C217026' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C217026' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}}]}}]}

#39

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C70793"}},{"name":"displayLanguage","valueCode":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"965d12b7-26e5-4742-8287-b739fab0f666"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1766
content-type:application/fhir+json
date:Thu, 31 Jul 2025 20:40:28 GMT
last-modified:Thu, 31 Jul 2025 20:40:28 GMT
pragma:no-cache
server:nginx
x-request-id:233-7001760

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C70793"},{"name" : "message","valueString" : "Unknown Code 'C70793' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C70793' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C70793 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C70793\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl| (from fhir.tx.support.r4#0.30.0)\" (content = fragment)\r\n"}]}

#40

POST https://tx.fhir.org/r5/ValueSet/$batch-validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C215670"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C215669"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C93478"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:3545
content-type:application/fhir+json
date:Thu, 31 Jul 2025 20:40:28 GMT
last-modified:Thu, 31 Jul 2025 20:40:28 GMT
pragma:no-cache
server:nginx
x-request-id:233-7001762

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#41

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
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#42

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
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#43

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#45

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#46

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#47

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#48

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and Pharmacogenomics"},{"code":"C218604","display":"8.6.2 Pharmacodynamic Biomarkers"},{"code":"C218605","display":"8.6.3 Other Biomarkers"},{"code":"C218606","display":"8.7 Immunogenicity Assessments"},{"code":"C218607","display":"8.8 Medical Resource Utilisation and Health Economics"},{"code":"C218608","display":"9 ADVERSE EVENTS, SERIOUS ADVERSE EVENTS, PRODUCT COMPLAINTS, PREGNANCY AND POSTPARTUM INFORMATION, AND SPECIAL SAFETY SITUATIONS"},{"code":"C218609","display":"9.1 Definitions"},{"code":"C218610","display":"9.1.1 Definitions of Adverse Events"},{"code":"C218611","display":"9.1.2 Definitions of Serious Adverse Events"},{"code":"C218612","display":"9.1.3 Definitions of Product Complaints"},{"code":"C218613","display":"9.1.3.1 Definition of Medical Device Product Complaints"},{"code":"C218614","display":"9.2 Timing and Procedures for Collection and Reporting"},{"code":"C218615","display":"9.2.1 Timing"},{"code":"C218616","display":"9.2.2 Collection 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Objective(s)"},{"code":"C218630","display":"10.4.1 Primary Objective"},{"code":"C218631","display":"10.4.1.1 Statistical Analysis Method"},{"code":"C218632","display":"10.4.1.2 Handling of Data in Relation to Primary Estimand(s)"},{"code":"C218633","display":"10.4.1.3 Handling of Missing Data in Relation to Primary Estimand(s)"},{"code":"C218634","display":"10.4.1.4 Sensitivity Analysis"},{"code":"C218635","display":"10.4.1.5 Supplementary Analysis"},{"code":"C218636","display":"10.5 Analyses Associated with the Secondary Objective(s)"},{"code":"C218637","display":"10.5.1 Secondary Objective"},{"code":"C218638","display":"10.5.1.1 Statistical Analysis Method"},{"code":"C218639","display":"10.5.1.2 Handling of Data in Relation to Secondary Estimand(s)"},{"code":"C218640","display":"10.5.1.3 Handling of Missing Data in Relation to Secondary Estimand(s)"},{"code":"C218641","display":"10.5.1.4 Sensitivity Analysis"},{"code":"C218642","display":"10.5.1.5 Supplementary Analysis"},{"code":"C218643","display":"10.6 Analyses Associated with the Exploratory Objective(s)"},{"code":"C218644","display":"10.7 Safety Analyses"},{"code":"C218645","display":"10.8 Other Analyses"},{"code":"C218646","display":"10.9 Interim Analyses"},{"code":"C218647","display":"10.10 Multiplicity Adjustments"},{"code":"C218648","display":"10.11 Sample Size Determination"},{"code":"C218649","display":"11 TRIAL OVERSIGHT AND OTHER GENERAL CONSIDERATIONS"},{"code":"C218650","display":"11.1 Regulatory and Ethical Considerations"},{"code":"C218651","display":"11.2 Trial Oversight"},{"code":"C218652","display":"11.2.1 Investigator Responsibilities"},{"code":"C218653","display":"11.2.2 Sponsor Responsibilities"},{"code":"C218654","display":"11.3 Informed Consent Process"},{"code":"C218655","display":"11.3.1 Informed Consent for Rescreening"},{"code":"C218656","display":"11.3.2 Informed Consent for Use of Remaining Samples in Exploratory Research"},{"code":"C218657","display":"11.4 Committees"},{"code":"C218658","display":"11.5 Insurance and Indemnity"},{"code":"C218659","display":"11.6 Risk-Based Quality Management"},{"code":"C218660","display":"11.7 Data Governance"},{"code":"C218661","display":"11.8 Data Protection"},{"code":"C218662","display":"11.9 Source Data"},{"code":"C218663","display":"11.10 Protocol Deviations"},{"code":"C218664","display":"11.11 Early Site Closure"},{"code":"C218665","display":"11.12 Data Dissemination"},{"code":"C218666","display":"12 APPENDIX: SUPPORTING DETAILS"},{"code":"C218667","display":"12.1 Clinical Laboratory Tests"},{"code":"C218668","display":"12.2 Country/Region-Specific Differences"},{"code":"C218669","display":"12.3 Prior Protocol Amendment(s)"},{"code":"C218670","display":"13 APPENDIX: GLOSSARY OF TERMS AND ABBREVIATIONS"},{"code":"C218671","display":"14 APPENDIX: REFERENCES"}]}]}}},{"name":"cache-id","valueId":"965d12b7-26e5-4742-8287-b739fab0f666"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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#49

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
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{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C218675","display":"Sponsor Investigational Product Code"}},{"name":"displayLanguage","valueCode":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"965d12b7-26e5-4742-8287-b739fab0f666"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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#50

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
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#51

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
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{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C71898"}},{"name":"displayLanguage","valueCode":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"965d12b7-26e5-4742-8287-b739fab0f666"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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#52

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
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x-request-id:233-7001843

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "code","valueCode" : "C217026"},{"name" : "message","valueString" : "The provided code 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C217026' was not found in the value set 'http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-study-amendment-scope-vs|1.0.0-ballot'; Unknown Code 'C217026' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C217026' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["code"],"expression" : ["code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "The provided code 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C217026' was not found in the value set 'http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-study-amendment-scope-vs|1.0.0-ballot'"},"location" : ["code"],"expression" : ["code"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-study-amendment-scope-vs|1.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-study-amendment-scope-vs|1.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-study-amendment-scope-vs|1.0.0-ballot: CodeSystem found: \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl| (from fhir.tx.support.r4#0.30.0)\"\r\n16 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-study-amendment-scope-vs|1.0.0-ballot: Validate \"[#C217026 (\"\")]\" and infer system\r\n16 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-study-amendment-scope-vs|1.0.0-ballot: Check \"#C217026\"\r\n16 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-study-amendment-scope-vs|1.0.0-ballot: Inferred CodeSystem = \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl\"\r\n16 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-study-amendment-scope-vs|1.0.0-ballot: CodeSystem found: http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl| (from fhir.tx.support.r4#0.30.0) for http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl\r\n32 16: 16ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-study-amendment-scope-vs|1.0.0-ballot: Code \"C217026\" in concept list, but not found in http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl| (from fhir.tx.support.r4#0.30.0)\r\n"}]}

#53

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"urn:iso:std:iso:3166","code":"DE"}},{"name":"displayLanguage","valueCode":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"urn:uuid:e8f3135a-1a72-4be8-90a6-981714afc950","status":"active","compose":{"include":[{"system":"urn:iso:std:iso:3166","filter":[{"property":"code","op":"regex","value":"[A-Z]{2}"}]}]}}},{"name":"cache-id","valueId":"965d12b7-26e5-4742-8287-b739fab0f666"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1101
content-type:application/fhir+json
date:Thu, 31 Jul 2025 20:40:40 GMT
last-modified:Thu, 31 Jul 2025 20:40:40 GMT
pragma:no-cache
server:nginx
x-request-id:233-7001845

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "urn:iso:std:iso:3166"},{"name" : "code","valueCode" : "DE"},{"name" : "version","valueString" : "2018"},{"name" : "display","valueString" : "Germany"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms urn:uuid:e8f3135a-1a72-4be8-90a6-981714afc950: Analysing\r\n16 0: 0ms urn:uuid:e8f3135a-1a72-4be8-90a6-981714afc950: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms urn:uuid:e8f3135a-1a72-4be8-90a6-981714afc950: CodeSystem found: \"urn:iso:std:iso:3166|2018\"\r\n16 0: 0ms urn:uuid:e8f3135a-1a72-4be8-90a6-981714afc950: Validate \"[urn:iso:std:iso:3166#DE (\"\")]\"\r\n16 0: 0ms urn:uuid:e8f3135a-1a72-4be8-90a6-981714afc950: Check \"urn:iso:std:iso:3166#DE\"\r\n16 0: 0ms urn:uuid:e8f3135a-1a72-4be8-90a6-981714afc950: CodeSystem found: urn:iso:std:iso:3166|2018 for urn:iso:std:iso:3166\r\n16 0: 0ms urn:uuid:e8f3135a-1a72-4be8-90a6-981714afc950: Filter \"code regex [A-Z]{2}\": Code \"DE\" found in urn:iso:std:iso:3166|2018\r\n"}]}

#54

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"inferSystem","valueBoolean":true},{"name":"code","valueCode":"DE"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"urn:uuid:cb803306-0439-4001-a3e3-2d82a198c3ca","status":"active","compose":{"include":[{"system":"urn:iso:std:iso:3166","filter":[{"property":"code","op":"regex","value":"[A-Z]{2}"}]}]}}},{"name":"cache-id","valueId":"965d12b7-26e5-4742-8287-b739fab0f666"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1387
content-type:application/fhir+json
date:Thu, 31 Jul 2025 20:40:40 GMT
last-modified:Thu, 31 Jul 2025 20:40:40 GMT
pragma:no-cache
server:nginx
x-request-id:233-7001847

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "urn:iso:std:iso:3166"},{"name" : "code","valueCode" : "DE"},{"name" : "version","valueString" : "2018"},{"name" : "display","valueString" : "Germany"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms urn:uuid:cb803306-0439-4001-a3e3-2d82a198c3ca: Analysing\r\n0 0: 0ms urn:uuid:cb803306-0439-4001-a3e3-2d82a198c3ca: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms urn:uuid:cb803306-0439-4001-a3e3-2d82a198c3ca: CodeSystem found: \"urn:iso:std:iso:3166|2018\"\r\n0 0: 0ms urn:uuid:cb803306-0439-4001-a3e3-2d82a198c3ca: Validate \"[#DE (\"\")]\" and infer system\r\n0 0: 0ms urn:uuid:cb803306-0439-4001-a3e3-2d82a198c3ca: Check \"#DE\"\r\n0 0: tx-op\r\n0 0: 0ms start working\r\n0 0: 0ms compose #1\r\n0 0: 0ms compose #1\r\n0 0: 0ms prepare filters\r\n16 16: 16ms iterate filters\r\n31 15: 31ms iterate filters done\r\n31 0: 31ms finish up\r\n47 16: 47ms urn:uuid:cb803306-0439-4001-a3e3-2d82a198c3ca: Inferred CodeSystem = \"urn:iso:std:iso:3166\"\r\n47 0: 47ms urn:uuid:cb803306-0439-4001-a3e3-2d82a198c3ca: CodeSystem found: urn:iso:std:iso:3166|2018 for urn:iso:std:iso:3166\r\n47 0: 47ms urn:uuid:cb803306-0439-4001-a3e3-2d82a198c3ca: Filter \"code regex [A-Z]{2}\": Code \"DE\" found in urn:iso:std:iso:3166|2018\r\n"}]}

#55

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"urn:iso:std:iso:3166","code":"DE"}},{"name":"displayLanguage","valueCode":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"urn:uuid:01b9fb3f-4435-4210-b392-42ec5021acea","status":"active","compose":{"include":[{"system":"urn:iso:std:iso:3166","filter":[{"property":"code","op":"regex","value":"[A-Z]{3}"}]}]}}},{"name":"cache-id","valueId":"965d12b7-26e5-4742-8287-b739fab0f666"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1101
content-type:application/fhir+json
date:Thu, 31 Jul 2025 20:40:40 GMT
last-modified:Thu, 31 Jul 2025 20:40:40 GMT
pragma:no-cache
server:nginx
x-request-id:233-7001849

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "urn:iso:std:iso:3166"},{"name" : "code","valueCode" : "DE"},{"name" : "version","valueString" : "2018"},{"name" : "display","valueString" : "Germany"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms urn:uuid:01b9fb3f-4435-4210-b392-42ec5021acea: Analysing\r\n16 0: 0ms urn:uuid:01b9fb3f-4435-4210-b392-42ec5021acea: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms urn:uuid:01b9fb3f-4435-4210-b392-42ec5021acea: CodeSystem found: \"urn:iso:std:iso:3166|2018\"\r\n16 0: 0ms urn:uuid:01b9fb3f-4435-4210-b392-42ec5021acea: Validate \"[urn:iso:std:iso:3166#DE (\"\")]\"\r\n16 0: 0ms urn:uuid:01b9fb3f-4435-4210-b392-42ec5021acea: Check \"urn:iso:std:iso:3166#DE\"\r\n16 0: 0ms urn:uuid:01b9fb3f-4435-4210-b392-42ec5021acea: CodeSystem found: urn:iso:std:iso:3166|2018 for urn:iso:std:iso:3166\r\n16 0: 0ms urn:uuid:01b9fb3f-4435-4210-b392-42ec5021acea: Filter \"code regex [A-Z]{3}\": Code \"DE\" found in urn:iso:std:iso:3166|2018\r\n"}]}

#56

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"inferSystem","valueBoolean":true},{"name":"code","valueCode":"DE"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"urn:uuid:3ef797a4-7961-44b5-9705-c68a5e9dcb82","status":"active","compose":{"include":[{"system":"urn:iso:std:iso:3166","filter":[{"property":"code","op":"regex","value":"[A-Z]{3}"}]}]}}},{"name":"cache-id","valueId":"965d12b7-26e5-4742-8287-b739fab0f666"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2186
content-type:application/fhir+json
date:Thu, 31 Jul 2025 20:40:41 GMT
last-modified:Thu, 31 Jul 2025 20:40:41 GMT
pragma:no-cache
server:nginx
x-request-id:233-7001851

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "code","valueCode" : "DE"},{"name" : "message","valueString" : "The provided code '#DE' was not found in the value set 'urn:uuid:3ef797a4-7961-44b5-9705-c68a5e9dcb82'; The System URI could not be determined for the code 'DE' in the ValueSet 'urn:uuid:3ef797a4-7961-44b5-9705-c68a5e9dcb82'"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_INFER_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "cannot-infer"}],"text" : "The System URI could not be determined for the code 'DE' in the ValueSet 'urn:uuid:3ef797a4-7961-44b5-9705-c68a5e9dcb82'"},"location" : ["code"],"expression" : ["code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "The provided code '#DE' was not found in the value set 'urn:uuid:3ef797a4-7961-44b5-9705-c68a5e9dcb82'"},"location" : ["code"],"expression" : ["code"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms urn:uuid:3ef797a4-7961-44b5-9705-c68a5e9dcb82: Analysing\r\n15 0: 0ms urn:uuid:3ef797a4-7961-44b5-9705-c68a5e9dcb82: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms urn:uuid:3ef797a4-7961-44b5-9705-c68a5e9dcb82: CodeSystem found: \"urn:iso:std:iso:3166|2018\"\r\n15 0: 0ms urn:uuid:3ef797a4-7961-44b5-9705-c68a5e9dcb82: Validate \"[#DE (\"\")]\" and infer system\r\n15 0: 0ms urn:uuid:3ef797a4-7961-44b5-9705-c68a5e9dcb82: Check \"#DE\"\r\n15 0: tx-op\r\n15 0: 0ms start working\r\n15 0: 0ms compose #1\r\n15 0: 0ms compose #1\r\n15 0: 0ms prepare filters\r\n15 0: 0ms iterate filters\r\n31 16: 16ms iterate filters done\r\n31 0: 16ms finish up\r\n"}]}

#57

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":true},{"name":"cache-id","valueId":"965d12b7-26e5-4742-8287-b739fab0f666"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"urn:iso:std:iso:3166","filter":[{"property":"code","op":"regex","value":"[A-Z]{3}"}]}]}}}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:19783
content-type:application/fhir+json
date:Thu, 31 Jul 2025 20:40:41 GMT
last-modified:Thu, 31 Jul 2025 20:40:41 GMT
pragma:no-cache
server:nginx
x-request-id:233-7001853

{"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:8fa7e47b-985d-4aa9-80f0-2aaa998545c5","timestamp" : "2025-07-31T20:40:41.196Z","total" : 249,"offset" : 0,"parameter" : [{"name" : "displayLanguage","valueCode" : "en-US"},{"name" : "excludeNested","valueBoolean" : true},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "urn:iso:std:iso:3166|2018"},{"name" : "version","valueUri" : "urn:iso:std:iso:3166|2018"}],"contains" : [{"system" : "urn:iso:std:iso:3166","code" : "ABW","display" : "Aruba"},{"system" : "urn:iso:std:iso:3166","code" : "AFG","display" : "Afghanistan"},{"system" : "urn:iso:std:iso:3166","code" : "AGO","display" : "Angola"},{"system" : "urn:iso:std:iso:3166","code" : "AIA","display" : "Anguilla"},{"system" : "urn:iso:std:iso:3166","code" : "ALA","display" : "Eland Islands"},{"system" : "urn:iso:std:iso:3166","code" : "ALB","display" : "Albania"},{"system" : "urn:iso:std:iso:3166","code" : "AND","display" : "Andorra"},{"system" : "urn:iso:std:iso:3166","code" : "ARE","display" : "United Arab Emirates"},{"system" : "urn:iso:std:iso:3166","code" : "ARG","display" : "Argentina"},{"system" : "urn:iso:std:iso:3166","code" : "ARM","display" : "Armenia"},{"system" : "urn:iso:std:iso:3166","code" : "ASM","display" : "American Samoa"},{"system" : "urn:iso:std:iso:3166","code" : "ATA","display" : "Antarctica"},{"system" : "urn:iso:std:iso:3166","code" : "ATF","display" : "French Southern Territories"},{"system" : "urn:iso:std:iso:3166","code" : "ATG","display" : "Antigua and Barbuda"},{"system" : "urn:iso:std:iso:3166","code" : "AUS","display" : "Australia"},{"system" : "urn:iso:std:iso:3166","code" : "AUT","display" : "Austria"},{"system" : "urn:iso:std:iso:3166","code" : "AZE","display" : "Azerbaijan"},{"system" : "urn:iso:std:iso:3166","code" : "BDI","display" : "Burundi"},{"system" : "urn:iso:std:iso:3166","code" : "BEL","display" : 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{"resourceType":"Parameters","parameter":[{"name":"inferSystem","valueBoolean":true},{"name":"code","valueCode":"DE"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"m11-country-region-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":1},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"brr"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ImplementationGuide/hl7.fhir.uv.pharmaceutical-research-protocol"}]}}],"url":"http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-country-region-vs","version":"1.0.0-ballot","name":"M11CountryRegionVS","title":"Study Amendment Country Value Set","status":"draft","experimental":false,"date":"2025-07-31T20:39:04+00:00","publisher":"HL7 International / Biomedical Research and Regulation","contact":[{"name":"HL7 International / Biomedical Research and Regulation","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/rcrim"},{"system":"email","value":"UDP@HL7Vulcan.org"}]}],"description":"Codes drawn from \nISO 3166 Country Codes, Alpha 3; \nISO 3166 Country Codes, Alpha 2; \nGENC\ncountry affected by an amendment to a study.","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"compose":{"include":[{"valueSet":["http://hl7.org/fhir/ValueSet/iso3166-1-2"]},{"valueSet":["http://hl7.org/fhir/ValueSet/iso3166-1-3"]}]}}},{"name":"tx-resource","resource":{"resourceType":"ValueSet","id":"iso3166-1-2","meta":{"lastUpdated":"2025-04-01T12:16:37.966+11:00","profile":["http://hl7.org/fhir/StructureDefinition/shareablevalueset"]},"text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"fhir"}],"url":"http://hl7.org/fhir/ValueSet/iso3166-1-2","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.3351"}],"version":"6.0.0-ballot3","name":"Iso316612","title":"Iso 3166 Part 1: 2 Letter Codes","status":"active","experimental":false,"publisher":"HL7 International / FHIR Infrastructure","contact":[{"telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/fiwg"}]}],"description":"This value set defines the ISO 3166 Part 1 2-letter codes","compose":{"include":[{"system":"urn:iso:std:iso:3166","filter":[{"property":"code","op":"regex","value":"[A-Z]{2}"}]}]}}},{"name":"tx-resource","resource":{"resourceType":"ValueSet","id":"iso3166-1-3","meta":{"lastUpdated":"2025-04-01T12:16:37.966+11:00","profile":["http://hl7.org/fhir/StructureDefinition/shareablevalueset"]},"text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"fhir"}],"url":"http://hl7.org/fhir/ValueSet/iso3166-1-3","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.3352"}],"version":"6.0.0-ballot3","name":"Iso316613","title":"Iso 3166 Part 1: 3 Letter Codes","status":"active","experimental":false,"publisher":"HL7 International / FHIR Infrastructure","contact":[{"telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/fiwg"}]}],"description":"This value set defines the ISO 3166 Part 1 3-letter codes","compose":{"include":[{"system":"urn:iso:std:iso:3166","filter":[{"property":"code","op":"regex","value":"[A-Z]{3}"}]}]}}},{"name":"cache-id","valueId":"965d12b7-26e5-4742-8287-b739fab0f666"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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date:Thu, 31 Jul 2025 20:40:41 GMT
last-modified:Thu, 31 Jul 2025 20:40:41 GMT
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x-request-id:233-7001855

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "urn:iso:std:iso:3166"},{"name" : "code","valueCode" : "DE"},{"name" : "version","valueString" : "2018"},{"name" : "display","valueString" : "Germany"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n31 31: tx-op\r\n31 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-country-region-vs|1.0.0-ballot: Analysing\r\n31 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-country-region-vs|1.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n31 0: tx-op\r\n31 0: 0ms http://hl7.org/fhir/ValueSet/iso3166-1-2|6.0.0-ballot3: Analysing\r\n31 0: 0ms http://hl7.org/fhir/ValueSet/iso3166-1-2|6.0.0-ballot3: Parameters: disp-lang=en-US, default-to-latest\r\n31 0: 0ms http://hl7.org/fhir/ValueSet/iso3166-1-2|6.0.0-ballot3: CodeSystem found: \"urn:iso:std:iso:3166|2018\"\r\n31 0: tx-op\r\n31 0: 0ms http://hl7.org/fhir/ValueSet/iso3166-1-3|6.0.0-ballot3: Analysing\r\n31 0: 0ms http://hl7.org/fhir/ValueSet/iso3166-1-3|6.0.0-ballot3: Parameters: disp-lang=en-US, default-to-latest\r\n31 0: 0ms http://hl7.org/fhir/ValueSet/iso3166-1-3|6.0.0-ballot3: CodeSystem found: \"urn:iso:std:iso:3166|2018\"\r\n31 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-country-region-vs|1.0.0-ballot: Validate \"[#DE (\"\")]\" and infer system\r\n31 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-country-region-vs|1.0.0-ballot: Check \"#DE\"\r\n31 0: tx-op\r\n31 0: 0ms start working\r\n31 0: 0ms compose #1\r\n31 0: 0ms compose #1\r\n31 0: 0ms import value set http://hl7.org/fhir/ValueSet/iso3166-1-2\r\n31 0: not in cache\r\n31 0: tx-op\r\n31 0: 0ms start working\r\n31 0: 0ms compose #1\r\n31 0: 0ms compose #1\r\n31 0: 0ms prepare filters\r\n31 0: 0ms iterate filters\r\n62 31: 31ms iterate filters done\r\n62 0: 31ms finish up\r\n78 16: 47ms import value set http://hl7.org/fhir/ValueSet/iso3166-1-3\r\n78 0: not in cache\r\n78 0: tx-op\r\n78 0: 47ms start working\r\n78 0: 47ms compose #1\r\n78 0: 47ms compose #1\r\n94 16: 63ms prepare filters\r\n94 0: 63ms iterate filters\r\n109 15: 78ms iterate filters done\r\n109 0: 78ms finish up\r\n125 16: 94ms finish up\r\n156 31: 125ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-country-region-vs|1.0.0-ballot: Inferred CodeSystem = \"urn:iso:std:iso:3166\"\r\n156 0: 125ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-country-region-vs|1.0.0-ballot: Check included value set http://hl7.org/fhir/ValueSet/iso3166-1-2\r\n156 0: 125ms http://hl7.org/fhir/ValueSet/iso3166-1-2|6.0.0-ballot3: Check \"urn:iso:std:iso:3166#DE\"\r\n156 0: 125ms http://hl7.org/fhir/ValueSet/iso3166-1-2|6.0.0-ballot3: CodeSystem found: urn:iso:std:iso:3166|2018 for urn:iso:std:iso:3166\r\n172 16: 141ms http://hl7.org/fhir/ValueSet/iso3166-1-2|6.0.0-ballot3: Filter \"code regex [A-Z]{2}\": Code \"DE\" found in urn:iso:std:iso:3166|2018\r\n"}]}

#59

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"urn:iso:std:iso:3166","code":"GB"}},{"name":"displayLanguage","valueCode":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"urn:uuid:6c46c7d1-da2e-4cdd-9325-6935e475ceaa","status":"active","compose":{"include":[{"system":"urn:iso:std:iso:3166","filter":[{"property":"code","op":"regex","value":"[A-Z]{2}"}]}]}}},{"name":"cache-id","valueId":"965d12b7-26e5-4742-8287-b739fab0f666"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1146
content-type:application/fhir+json
date:Thu, 31 Jul 2025 20:40:41 GMT
last-modified:Thu, 31 Jul 2025 20:40:41 GMT
pragma:no-cache
server:nginx
x-request-id:233-7001857

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "urn:iso:std:iso:3166"},{"name" : "code","valueCode" : "GB"},{"name" : "version","valueString" : "2018"},{"name" : "display","valueString" : "United Kingdom of Great Britain and Northern Ireland"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms urn:uuid:6c46c7d1-da2e-4cdd-9325-6935e475ceaa: Analysing\r\n16 0: 0ms urn:uuid:6c46c7d1-da2e-4cdd-9325-6935e475ceaa: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms urn:uuid:6c46c7d1-da2e-4cdd-9325-6935e475ceaa: CodeSystem found: \"urn:iso:std:iso:3166|2018\"\r\n16 0: 0ms urn:uuid:6c46c7d1-da2e-4cdd-9325-6935e475ceaa: Validate \"[urn:iso:std:iso:3166#GB (\"\")]\"\r\n16 0: 0ms urn:uuid:6c46c7d1-da2e-4cdd-9325-6935e475ceaa: Check \"urn:iso:std:iso:3166#GB\"\r\n16 0: 0ms urn:uuid:6c46c7d1-da2e-4cdd-9325-6935e475ceaa: CodeSystem found: urn:iso:std:iso:3166|2018 for urn:iso:std:iso:3166\r\n16 0: 0ms urn:uuid:6c46c7d1-da2e-4cdd-9325-6935e475ceaa: Filter \"code regex [A-Z]{2}\": Code \"GB\" found in urn:iso:std:iso:3166|2018\r\n"}]}

#60

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"inferSystem","valueBoolean":true},{"name":"code","valueCode":"GB"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"urn:uuid:84c14339-2e9a-4a7a-a57f-ff5a5944fd1a","status":"active","compose":{"include":[{"system":"urn:iso:std:iso:3166","filter":[{"property":"code","op":"regex","value":"[A-Z]{2}"}]}]}}},{"name":"cache-id","valueId":"965d12b7-26e5-4742-8287-b739fab0f666"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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connection:keep-alive
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content-type:application/fhir+json
date:Thu, 31 Jul 2025 20:40:41 GMT
last-modified:Thu, 31 Jul 2025 20:40:41 GMT
pragma:no-cache
server:nginx
x-request-id:233-7001859

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "urn:iso:std:iso:3166"},{"name" : "code","valueCode" : "GB"},{"name" : "version","valueString" : "2018"},{"name" : "display","valueString" : "United Kingdom of Great Britain and Northern Ireland"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms urn:uuid:84c14339-2e9a-4a7a-a57f-ff5a5944fd1a: Analysing\r\n16 0: 0ms urn:uuid:84c14339-2e9a-4a7a-a57f-ff5a5944fd1a: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms urn:uuid:84c14339-2e9a-4a7a-a57f-ff5a5944fd1a: CodeSystem found: \"urn:iso:std:iso:3166|2018\"\r\n16 0: 0ms urn:uuid:84c14339-2e9a-4a7a-a57f-ff5a5944fd1a: Validate \"[#GB (\"\")]\" and infer system\r\n16 0: 0ms urn:uuid:84c14339-2e9a-4a7a-a57f-ff5a5944fd1a: Check \"#GB\"\r\n16 0: tx-op\r\n16 0: 0ms start working\r\n16 0: 0ms compose #1\r\n16 0: 0ms compose #1\r\n16 0: 0ms prepare filters\r\n16 0: 0ms iterate filters\r\n31 15: 15ms iterate filters done\r\n31 0: 15ms finish up\r\n47 16: 31ms urn:uuid:84c14339-2e9a-4a7a-a57f-ff5a5944fd1a: Inferred CodeSystem = \"urn:iso:std:iso:3166\"\r\n47 0: 31ms urn:uuid:84c14339-2e9a-4a7a-a57f-ff5a5944fd1a: CodeSystem found: urn:iso:std:iso:3166|2018 for urn:iso:std:iso:3166\r\n47 0: 31ms urn:uuid:84c14339-2e9a-4a7a-a57f-ff5a5944fd1a: Filter \"code regex [A-Z]{2}\": Code \"GB\" found in urn:iso:std:iso:3166|2018\r\n"}]}

#61

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"urn:iso:std:iso:3166","code":"GB"}},{"name":"displayLanguage","valueCode":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"urn:uuid:21d26361-7fae-4578-bec2-e653a0c4076c","status":"active","compose":{"include":[{"system":"urn:iso:std:iso:3166","filter":[{"property":"code","op":"regex","value":"[A-Z]{3}"}]}]}}},{"name":"cache-id","valueId":"965d12b7-26e5-4742-8287-b739fab0f666"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
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cache-control:public, max-age=600
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content-type:application/fhir+json
date:Thu, 31 Jul 2025 20:40:41 GMT
last-modified:Thu, 31 Jul 2025 20:40:41 GMT
pragma:no-cache
server:nginx
x-request-id:233-7001861

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "urn:iso:std:iso:3166"},{"name" : "code","valueCode" : "GB"},{"name" : "version","valueString" : "2018"},{"name" : "display","valueString" : "United Kingdom of Great Britain and Northern Ireland"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms urn:uuid:21d26361-7fae-4578-bec2-e653a0c4076c: Analysing\r\n16 0: 0ms urn:uuid:21d26361-7fae-4578-bec2-e653a0c4076c: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms urn:uuid:21d26361-7fae-4578-bec2-e653a0c4076c: CodeSystem found: \"urn:iso:std:iso:3166|2018\"\r\n16 0: 0ms urn:uuid:21d26361-7fae-4578-bec2-e653a0c4076c: Validate \"[urn:iso:std:iso:3166#GB (\"\")]\"\r\n16 0: 0ms urn:uuid:21d26361-7fae-4578-bec2-e653a0c4076c: Check \"urn:iso:std:iso:3166#GB\"\r\n16 0: 0ms urn:uuid:21d26361-7fae-4578-bec2-e653a0c4076c: CodeSystem found: urn:iso:std:iso:3166|2018 for urn:iso:std:iso:3166\r\n16 0: 0ms urn:uuid:21d26361-7fae-4578-bec2-e653a0c4076c: Filter \"code regex [A-Z]{3}\": Code \"GB\" found in urn:iso:std:iso:3166|2018\r\n"}]}

#62

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"inferSystem","valueBoolean":true},{"name":"code","valueCode":"GB"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"urn:uuid:cef16fce-acf3-4535-9e11-20ca49283d09","status":"active","compose":{"include":[{"system":"urn:iso:std:iso:3166","filter":[{"property":"code","op":"regex","value":"[A-Z]{3}"}]}]}}},{"name":"cache-id","valueId":"965d12b7-26e5-4742-8287-b739fab0f666"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2191
content-type:application/fhir+json
date:Thu, 31 Jul 2025 20:40:42 GMT
last-modified:Thu, 31 Jul 2025 20:40:42 GMT
pragma:no-cache
server:nginx
x-request-id:233-7001863

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "code","valueCode" : "GB"},{"name" : "message","valueString" : "The provided code '#GB' was not found in the value set 'urn:uuid:cef16fce-acf3-4535-9e11-20ca49283d09'; The System URI could not be determined for the code 'GB' in the ValueSet 'urn:uuid:cef16fce-acf3-4535-9e11-20ca49283d09'"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_INFER_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "cannot-infer"}],"text" : "The System URI could not be determined for the code 'GB' in the ValueSet 'urn:uuid:cef16fce-acf3-4535-9e11-20ca49283d09'"},"location" : ["code"],"expression" : ["code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "The provided code '#GB' was not found in the value set 'urn:uuid:cef16fce-acf3-4535-9e11-20ca49283d09'"},"location" : ["code"],"expression" : ["code"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms urn:uuid:cef16fce-acf3-4535-9e11-20ca49283d09: Analysing\r\n0 0: 0ms urn:uuid:cef16fce-acf3-4535-9e11-20ca49283d09: Parameters: disp-lang=en-US, default-to-latest\r\n16 16: 16ms urn:uuid:cef16fce-acf3-4535-9e11-20ca49283d09: CodeSystem found: \"urn:iso:std:iso:3166|2018\"\r\n16 0: 16ms urn:uuid:cef16fce-acf3-4535-9e11-20ca49283d09: Validate \"[#GB (\"\")]\" and infer system\r\n16 0: 16ms urn:uuid:cef16fce-acf3-4535-9e11-20ca49283d09: Check \"#GB\"\r\n16 0: tx-op\r\n16 0: 16ms start working\r\n16 0: 16ms compose #1\r\n16 0: 16ms compose #1\r\n16 0: 16ms prepare filters\r\n16 0: 16ms iterate filters\r\n32 16: 32ms iterate filters done\r\n32 0: 32ms finish up\r\n"}]}

#63

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"inferSystem","valueBoolean":true},{"name":"code","valueCode":"GB"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"m11-country-region-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":1},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"brr"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ImplementationGuide/hl7.fhir.uv.pharmaceutical-research-protocol"}]}}],"url":"http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-country-region-vs","version":"1.0.0-ballot","name":"M11CountryRegionVS","title":"Study Amendment Country Value Set","status":"draft","experimental":false,"date":"2025-07-31T20:39:04+00:00","publisher":"HL7 International / Biomedical Research and Regulation","contact":[{"name":"HL7 International / Biomedical Research and Regulation","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/rcrim"},{"system":"email","value":"UDP@HL7Vulcan.org"}]}],"description":"Codes drawn from \nISO 3166 Country Codes, Alpha 3; \nISO 3166 Country Codes, Alpha 2; \nGENC\ncountry affected by an amendment to a study.","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"compose":{"include":[{"valueSet":["http://hl7.org/fhir/ValueSet/iso3166-1-2"]},{"valueSet":["http://hl7.org/fhir/ValueSet/iso3166-1-3"]}]}}},{"name":"tx-resource","resource":{"resourceType":"ValueSet","id":"iso3166-1-2","meta":{"lastUpdated":"2025-04-01T12:16:37.966+11:00","profile":["http://hl7.org/fhir/StructureDefinition/shareablevalueset"]},"text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"fhir"}],"url":"http://hl7.org/fhir/ValueSet/iso3166-1-2","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.3351"}],"version":"6.0.0-ballot3","name":"Iso316612","title":"Iso 3166 Part 1: 2 Letter Codes","status":"active","experimental":false,"publisher":"HL7 International / FHIR Infrastructure","contact":[{"telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/fiwg"}]}],"description":"This value set defines the ISO 3166 Part 1 2-letter codes","compose":{"include":[{"system":"urn:iso:std:iso:3166","filter":[{"property":"code","op":"regex","value":"[A-Z]{2}"}]}]}}},{"name":"tx-resource","resource":{"resourceType":"ValueSet","id":"iso3166-1-3","meta":{"lastUpdated":"2025-04-01T12:16:37.966+11:00","profile":["http://hl7.org/fhir/StructureDefinition/shareablevalueset"]},"text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"fhir"}],"url":"http://hl7.org/fhir/ValueSet/iso3166-1-3","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.3352"}],"version":"6.0.0-ballot3","name":"Iso316613","title":"Iso 3166 Part 1: 3 Letter Codes","status":"active","experimental":false,"publisher":"HL7 International / FHIR Infrastructure","contact":[{"telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/fiwg"}]}],"description":"This value set defines the ISO 3166 Part 1 3-letter codes","compose":{"include":[{"system":"urn:iso:std:iso:3166","filter":[{"property":"code","op":"regex","value":"[A-Z]{3}"}]}]}}},{"name":"cache-id","valueId":"965d12b7-26e5-4742-8287-b739fab0f666"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "urn:iso:std:iso:3166"},{"name" : "code","valueCode" : "GB"},{"name" : "version","valueString" : "2018"},{"name" : "display","valueString" : "United Kingdom of Great Britain and Northern Ireland"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n32 32: tx-op\r\n32 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-country-region-vs|1.0.0-ballot: Analysing\r\n32 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-country-region-vs|1.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n32 0: tx-op\r\n32 0: 0ms http://hl7.org/fhir/ValueSet/iso3166-1-2|6.0.0-ballot3: Analysing\r\n32 0: 0ms http://hl7.org/fhir/ValueSet/iso3166-1-2|6.0.0-ballot3: Parameters: disp-lang=en-US, default-to-latest\r\n32 0: 0ms http://hl7.org/fhir/ValueSet/iso3166-1-2|6.0.0-ballot3: CodeSystem found: \"urn:iso:std:iso:3166|2018\"\r\n32 0: tx-op\r\n32 0: 0ms http://hl7.org/fhir/ValueSet/iso3166-1-3|6.0.0-ballot3: Analysing\r\n32 0: 0ms http://hl7.org/fhir/ValueSet/iso3166-1-3|6.0.0-ballot3: Parameters: disp-lang=en-US, default-to-latest\r\n32 0: 0ms http://hl7.org/fhir/ValueSet/iso3166-1-3|6.0.0-ballot3: CodeSystem found: \"urn:iso:std:iso:3166|2018\"\r\n32 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-country-region-vs|1.0.0-ballot: Validate \"[#GB (\"\")]\" and infer system\r\n32 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-country-region-vs|1.0.0-ballot: Check \"#GB\"\r\n32 0: tx-op\r\n32 0: 0ms start working\r\n32 0: 0ms compose #1\r\n32 0: 0ms compose #1\r\n47 15: 15ms import value set http://hl7.org/fhir/ValueSet/iso3166-1-2\r\n47 0: not in cache\r\n47 0: tx-op\r\n47 0: 15ms start working\r\n47 0: 15ms compose #1\r\n47 0: 15ms compose #1\r\n47 0: 15ms prepare filters\r\n47 0: 15ms iterate filters\r\n63 16: 31ms iterate filters done\r\n63 0: 31ms finish up\r\n94 31: 62ms import value set http://hl7.org/fhir/ValueSet/iso3166-1-3\r\n94 0: not in cache\r\n94 0: tx-op\r\n94 0: 62ms start working\r\n94 0: 62ms compose #1\r\n94 0: 62ms compose #1\r\n94 0: 62ms prepare filters\r\n94 0: 62ms iterate filters\r\n110 16: 78ms iterate filters done\r\n110 0: 78ms finish up\r\n141 31: 109ms finish up\r\n172 31: 140ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-country-region-vs|1.0.0-ballot: Inferred CodeSystem = \"urn:iso:std:iso:3166\"\r\n172 0: 140ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-country-region-vs|1.0.0-ballot: Check included value set http://hl7.org/fhir/ValueSet/iso3166-1-2\r\n172 0: 140ms http://hl7.org/fhir/ValueSet/iso3166-1-2|6.0.0-ballot3: Check \"urn:iso:std:iso:3166#GB\"\r\n172 0: 140ms http://hl7.org/fhir/ValueSet/iso3166-1-2|6.0.0-ballot3: CodeSystem found: urn:iso:std:iso:3166|2018 for urn:iso:std:iso:3166\r\n172 0: 140ms http://hl7.org/fhir/ValueSet/iso3166-1-2|6.0.0-ballot3: Filter \"code regex [A-Z]{2}\": Code \"GB\" found in urn:iso:std:iso:3166|2018\r\n"}]}

#64

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"urn:iso:std:iso:3166","code":"AU-NSW"}},{"name":"displayLanguage","valueCode":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"urn:uuid:6fdb704f-c226-40e9-ab19-a949dfe359a8","status":"active","compose":{"include":[{"system":"urn:iso:std:iso:3166","filter":[{"property":"code","op":"regex","value":"[A-Z]{2}"}]}]}}},{"name":"cache-id","valueId":"965d12b7-26e5-4742-8287-b739fab0f666"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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last-modified:Thu, 31 Jul 2025 20:40:42 GMT
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "urn:iso:std:iso:3166"},{"name" : "code","valueCode" : "AU-NSW"},{"name" : "message","valueString" : "The provided code 'urn:iso:std:iso:3166#AU-NSW' was not found in the value set 'urn:uuid:6fdb704f-c226-40e9-ab19-a949dfe359a8'; Unknown code 'AU-NSW' in the CodeSystem 'urn:iso:std:iso:3166' version '2018'"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "Unknown_Code_in_Version"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown code 'AU-NSW' in the CodeSystem 'urn:iso:std:iso:3166' version '2018'"},"location" : ["Coding.code"],"expression" : ["Coding.code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "The provided code 'urn:iso:std:iso:3166#AU-NSW' was not found in the value set 'urn:uuid:6fdb704f-c226-40e9-ab19-a949dfe359a8'"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms urn:uuid:6fdb704f-c226-40e9-ab19-a949dfe359a8: Analysing\r\n15 0: 0ms urn:uuid:6fdb704f-c226-40e9-ab19-a949dfe359a8: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms urn:uuid:6fdb704f-c226-40e9-ab19-a949dfe359a8: CodeSystem found: \"urn:iso:std:iso:3166|2018\"\r\n15 0: 0ms urn:uuid:6fdb704f-c226-40e9-ab19-a949dfe359a8: Validate \"[urn:iso:std:iso:3166#AU-NSW (\"\")]\"\r\n15 0: 0ms urn:uuid:6fdb704f-c226-40e9-ab19-a949dfe359a8: Check \"urn:iso:std:iso:3166#AU-NSW\"\r\n15 0: 0ms urn:uuid:6fdb704f-c226-40e9-ab19-a949dfe359a8: CodeSystem found: urn:iso:std:iso:3166|2018 for urn:iso:std:iso:3166\r\n15 0: 0ms urn:uuid:6fdb704f-c226-40e9-ab19-a949dfe359a8: Filter \"code regex [A-Z]{2}\": Code \"AU-NSW\" not found in urn:iso:std:iso:3166|2018\r\n"}]}

#65

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"urn:iso:std:iso:3166","code":"AU-NSW"}},{"name":"displayLanguage","valueCode":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"urn:uuid:682203aa-cc5a-438f-97fc-5141b905840e","status":"active","compose":{"include":[{"system":"urn:iso:std:iso:3166","filter":[{"property":"code","op":"regex","value":"[A-Z]{3}"}]}]}}},{"name":"cache-id","valueId":"965d12b7-26e5-4742-8287-b739fab0f666"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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last-modified:Thu, 31 Jul 2025 20:40:42 GMT
pragma:no-cache
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x-request-id:233-7001869

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "urn:iso:std:iso:3166"},{"name" : "code","valueCode" : "AU-NSW"},{"name" : "message","valueString" : "The provided code 'urn:iso:std:iso:3166#AU-NSW' was not found in the value set 'urn:uuid:682203aa-cc5a-438f-97fc-5141b905840e'; Unknown code 'AU-NSW' in the CodeSystem 'urn:iso:std:iso:3166' version '2018'"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "Unknown_Code_in_Version"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown code 'AU-NSW' in the CodeSystem 'urn:iso:std:iso:3166' version '2018'"},"location" : ["Coding.code"],"expression" : ["Coding.code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "The provided code 'urn:iso:std:iso:3166#AU-NSW' was not found in the value set 'urn:uuid:682203aa-cc5a-438f-97fc-5141b905840e'"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms urn:uuid:682203aa-cc5a-438f-97fc-5141b905840e: Analysing\r\n16 0: 0ms urn:uuid:682203aa-cc5a-438f-97fc-5141b905840e: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms urn:uuid:682203aa-cc5a-438f-97fc-5141b905840e: CodeSystem found: \"urn:iso:std:iso:3166|2018\"\r\n16 0: 0ms urn:uuid:682203aa-cc5a-438f-97fc-5141b905840e: Validate \"[urn:iso:std:iso:3166#AU-NSW (\"\")]\"\r\n16 0: 0ms urn:uuid:682203aa-cc5a-438f-97fc-5141b905840e: Check \"urn:iso:std:iso:3166#AU-NSW\"\r\n16 0: 0ms urn:uuid:682203aa-cc5a-438f-97fc-5141b905840e: CodeSystem found: urn:iso:std:iso:3166|2018 for urn:iso:std:iso:3166\r\n16 0: 0ms urn:uuid:682203aa-cc5a-438f-97fc-5141b905840e: Filter \"code regex [A-Z]{3}\": Code \"AU-NSW\" not found in urn:iso:std:iso:3166|2018\r\n"}]}

#66

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"inferSystem","valueBoolean":true},{"name":"code","valueCode":"C41065"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"m11-amendment-scope-enrollment-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"brr"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ImplementationGuide/hl7.fhir.uv.pharmaceutical-research-protocol"}]}}],"url":"http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-amendment-scope-enrollment-vs","version":"1.0.0-ballot","name":"M11AmendmentScopeEnrollmentVS","title":"Study Amendment Scope Enrollment Value Set","status":"draft","experimental":false,"date":"2025-07-31T20:39:04+00:00","publisher":"HL7 International / Biomedical Research and Regulation","contact":[{"name":"HL7 International / Biomedical Research and Regulation","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/rcrim"},{"system":"email","value":"UDP@HL7Vulcan.org"}]}],"description":"Categorizing numbers affected by the amendment","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"compose":{"include":[{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","concept":[{"code":"C68846","display":"Globally"},{"code":"C41065","display":"Locally"},{"code":"C218489","display":"By Cohort"}]}]}}},{"name":"cache-id","valueId":"965d12b7-26e5-4742-8287-b739fab0f666"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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last-modified:Thu, 31 Jul 2025 20:40:42 GMT
pragma:no-cache
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x-request-id:233-7001871

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "code","valueCode" : "C41065"},{"name" : "message","valueString" : "The provided code 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C41065' was not found in the value set 'http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-amendment-scope-enrollment-vs|1.0.0-ballot'; Unknown Code 'C41065' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C41065' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["code"],"expression" : ["code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "The provided code 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C41065' was not found in the value set 'http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-amendment-scope-enrollment-vs|1.0.0-ballot'"},"location" : ["code"],"expression" : ["code"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-amendment-scope-enrollment-vs|1.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-amendment-scope-enrollment-vs|1.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-amendment-scope-enrollment-vs|1.0.0-ballot: CodeSystem found: \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl| (from fhir.tx.support.r4#0.30.0)\"\r\n16 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-amendment-scope-enrollment-vs|1.0.0-ballot: Validate \"[#C41065 (\"\")]\" and infer system\r\n16 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-amendment-scope-enrollment-vs|1.0.0-ballot: Check \"#C41065\"\r\n16 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-amendment-scope-enrollment-vs|1.0.0-ballot: Inferred CodeSystem = \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl\"\r\n16 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-amendment-scope-enrollment-vs|1.0.0-ballot: CodeSystem found: http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl| (from fhir.tx.support.r4#0.30.0) for http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl\r\n31 15: 15ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-amendment-scope-enrollment-vs|1.0.0-ballot: Code \"C41065\" in concept list, but not found in http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl| (from fhir.tx.support.r4#0.30.0)\r\n"}]}

#67

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"inferSystem","valueBoolean":true},{"name":"code","valueCode":"C68846"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"m11-amendment-scope-enrollment-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"brr"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ImplementationGuide/hl7.fhir.uv.pharmaceutical-research-protocol"}]}}],"url":"http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-amendment-scope-enrollment-vs","version":"1.0.0-ballot","name":"M11AmendmentScopeEnrollmentVS","title":"Study Amendment Scope Enrollment Value Set","status":"draft","experimental":false,"date":"2025-07-31T20:39:04+00:00","publisher":"HL7 International / Biomedical Research and Regulation","contact":[{"name":"HL7 International / Biomedical Research and Regulation","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/rcrim"},{"system":"email","value":"UDP@HL7Vulcan.org"}]}],"description":"Categorizing numbers affected by the amendment","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"compose":{"include":[{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","concept":[{"code":"C68846","display":"Globally"},{"code":"C41065","display":"Locally"},{"code":"C218489","display":"By Cohort"}]}]}}},{"name":"cache-id","valueId":"965d12b7-26e5-4742-8287-b739fab0f666"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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connection:keep-alive
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date:Thu, 31 Jul 2025 20:40:42 GMT
last-modified:Thu, 31 Jul 2025 20:40:42 GMT
pragma:no-cache
server:nginx
x-request-id:233-7001873

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "code","valueCode" : "C68846"},{"name" : "message","valueString" : "The provided code 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C68846' was not found in the value set 'http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-amendment-scope-enrollment-vs|1.0.0-ballot'; Unknown Code 'C68846' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C68846' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["code"],"expression" : ["code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "The provided code 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C68846' was not found in the value set 'http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-amendment-scope-enrollment-vs|1.0.0-ballot'"},"location" : ["code"],"expression" : ["code"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-amendment-scope-enrollment-vs|1.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-amendment-scope-enrollment-vs|1.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-amendment-scope-enrollment-vs|1.0.0-ballot: CodeSystem found: \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl| (from fhir.tx.support.r4#0.30.0)\"\r\n15 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-amendment-scope-enrollment-vs|1.0.0-ballot: Validate \"[#C68846 (\"\")]\" and infer system\r\n15 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-amendment-scope-enrollment-vs|1.0.0-ballot: Check \"#C68846\"\r\n15 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-amendment-scope-enrollment-vs|1.0.0-ballot: Inferred CodeSystem = \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl\"\r\n15 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-amendment-scope-enrollment-vs|1.0.0-ballot: CodeSystem found: http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl| (from fhir.tx.support.r4#0.30.0) for http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl\r\n31 16: 16ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-amendment-scope-enrollment-vs|1.0.0-ballot: Code \"C68846\" in concept list, but not found in http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl| (from fhir.tx.support.r4#0.30.0)\r\n"}]}

#68

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C218490","display":"Regulatory Agency Request To Amend"}},{"name":"displayLanguage","valueCode":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"965d12b7-26e5-4742-8287-b739fab0f666"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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cache-control:public, max-age=600
connection:keep-alive
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content-type:application/fhir+json
date:Thu, 31 Jul 2025 20:40:43 GMT
last-modified:Thu, 31 Jul 2025 20:40:43 GMT
pragma:no-cache
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C218490"},{"name" : "message","valueString" : "Unknown Code 'C218490' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C218490' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C218490 (\"Regulatory Agency Request To Amend\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C218490\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl| (from fhir.tx.support.r4#0.30.0)\" (content = fragment)\r\n"}]}

#69

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C218490"}},{"name":"displayLanguage","valueCode":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-study-amendment-reason-vs--0","version":"1.0.0-ballot","status":"active","compose":{"include":[{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","concept":[{"code":"C218490","display":"Regulatory Agency Request To Amend"},{"code":"C218491","display":"New Regulatory Guidance"},{"code":"C218492","display":"IRB/IEC Feedback"},{"code":"C218493","display":"New Safety Information Available"},{"code":"C218494","display":"Manufacturing Change"},{"code":"C218495","display":"IMP Addition"},{"code":"C218496","display":"Change In Strategy"},{"code":"C218497","display":"Change In Standard Of Care"},{"code":"C218498","display":"New Data Available (Other Than Safety Data)"},{"code":"C218499","display":"Investigator/Site Feedback"},{"code":"C218500","display":"Recruitment Difficulty"},{"code":"C218501","display":"Inconsistency And/Or Error In The Protocol"},{"code":"C218502","display":"Protocol Design Error"},{"code":"C17649","display":"Other"},{"code":"C48660","display":"Not Applicable"}]}]}}},{"name":"cache-id","valueId":"965d12b7-26e5-4742-8287-b739fab0f666"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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date:Thu, 31 Jul 2025 20:40:43 GMT
last-modified:Thu, 31 Jul 2025 20:40:43 GMT
pragma:no-cache
server:nginx
x-request-id:233-7001877

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C218490"},{"name" : "message","valueString" : "The provided code 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C218490' was not found in the value set 'http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-study-amendment-reason-vs--0|1.0.0-ballot'; Unknown Code 'C218490' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C218490' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "The provided code 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C218490' was not found in the value set 'http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-study-amendment-reason-vs--0|1.0.0-ballot'"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-study-amendment-reason-vs--0|1.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-study-amendment-reason-vs--0|1.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-study-amendment-reason-vs--0|1.0.0-ballot: CodeSystem found: \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl| (from fhir.tx.support.r4#0.30.0)\"\r\n0 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-study-amendment-reason-vs--0|1.0.0-ballot: Validate \"[http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C218490 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-study-amendment-reason-vs--0|1.0.0-ballot: Check \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C218490\"\r\n0 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-study-amendment-reason-vs--0|1.0.0-ballot: CodeSystem found: http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl| (from fhir.tx.support.r4#0.30.0) for http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl\r\n16 16: 16ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-study-amendment-reason-vs--0|1.0.0-ballot: Code \"C218490\" in concept list, but not found in http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl| (from fhir.tx.support.r4#0.30.0)\r\n"}]}

#70

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C218494","display":"Manufacturing Change"}},{"name":"displayLanguage","valueCode":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"965d12b7-26e5-4742-8287-b739fab0f666"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json
date:Thu, 31 Jul 2025 20:40:43 GMT
last-modified:Thu, 31 Jul 2025 20:40:43 GMT
pragma:no-cache
server:nginx
x-request-id:233-7001879

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C218494"},{"name" : "message","valueString" : "Unknown Code 'C218494' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C218494' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C218494 (\"Manufacturing Change\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C218494\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl| (from fhir.tx.support.r4#0.30.0)\" (content = fragment)\r\n"}]}

#71

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C218494"}},{"name":"displayLanguage","valueCode":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-study-amendment-reason-vs--0","version":"1.0.0-ballot","status":"active","compose":{"include":[{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","concept":[{"code":"C218490","display":"Regulatory Agency Request To Amend"},{"code":"C218491","display":"New Regulatory Guidance"},{"code":"C218492","display":"IRB/IEC Feedback"},{"code":"C218493","display":"New Safety Information Available"},{"code":"C218494","display":"Manufacturing Change"},{"code":"C218495","display":"IMP Addition"},{"code":"C218496","display":"Change In Strategy"},{"code":"C218497","display":"Change In Standard Of Care"},{"code":"C218498","display":"New Data Available (Other Than Safety Data)"},{"code":"C218499","display":"Investigator/Site Feedback"},{"code":"C218500","display":"Recruitment Difficulty"},{"code":"C218501","display":"Inconsistency And/Or Error In The Protocol"},{"code":"C218502","display":"Protocol Design Error"},{"code":"C17649","display":"Other"},{"code":"C48660","display":"Not Applicable"}]}]}}},{"name":"cache-id","valueId":"965d12b7-26e5-4742-8287-b739fab0f666"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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last-modified:Thu, 31 Jul 2025 20:40:43 GMT
pragma:no-cache
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x-request-id:233-7001881

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C218494"},{"name" : "message","valueString" : "The provided code 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C218494' was not found in the value set 'http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-study-amendment-reason-vs--0|1.0.0-ballot'; Unknown Code 'C218494' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C218494' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "The provided code 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C218494' was not found in the value set 'http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-study-amendment-reason-vs--0|1.0.0-ballot'"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-study-amendment-reason-vs--0|1.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-study-amendment-reason-vs--0|1.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-study-amendment-reason-vs--0|1.0.0-ballot: CodeSystem found: \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl| (from fhir.tx.support.r4#0.30.0)\"\r\n0 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-study-amendment-reason-vs--0|1.0.0-ballot: Validate \"[http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C218494 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-study-amendment-reason-vs--0|1.0.0-ballot: Check \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C218494\"\r\n0 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-study-amendment-reason-vs--0|1.0.0-ballot: CodeSystem found: http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl| (from fhir.tx.support.r4#0.30.0) for http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl\r\n16 16: 16ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-study-amendment-reason-vs--0|1.0.0-ballot: Code \"C218494\" in concept list, but not found in http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl| (from fhir.tx.support.r4#0.30.0)\r\n"}]}

#72

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
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{"resourceType":"Parameters","parameter":[{"name":"inferSystem","valueBoolean":true},{"name":"code","valueCode":"C49488"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"cdisc-yes-no-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"brr"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ImplementationGuide/hl7.fhir.uv.pharmaceutical-research-protocol"}]}}],"url":"http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/cdisc-yes-no-vs","version":"1.0.0-ballot","name":"CDISCSDTMYesNoUnknownVS","title":"CDISC Yes No Unknown Not Applicable Value Set","status":"draft","experimental":false,"date":"2025-07-31T20:39:04+00:00","publisher":"HL7 International / Biomedical Research and Regulation","contact":[{"name":"HL7 International / Biomedical Research and Regulation","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/rcrim"},{"system":"email","value":"UDP@HL7Vulcan.org"}]}],"description":"Contains all values from C66742 - CDISC SDTM Yes No Unknown or Not Applicable Response Terminology","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"compose":{"include":[{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","concept":[{"code":"C49487","display":"No"},{"code":"C48660","display":"Not Applicable"},{"code":"C17998","display":"Unknown"},{"code":"C49488","display":"Yes"}]}]}}},{"name":"cache-id","valueId":"965d12b7-26e5-4742-8287-b739fab0f666"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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last-modified:Thu, 31 Jul 2025 20:40:43 GMT
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "code","valueCode" : "C49488"},{"name" : "message","valueString" : "The provided code 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C49488' was not found in the value set 'http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/cdisc-yes-no-vs|1.0.0-ballot'; Unknown Code 'C49488' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C49488' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["code"],"expression" : ["code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "The provided code 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C49488' was not found in the value set 'http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/cdisc-yes-no-vs|1.0.0-ballot'"},"location" : ["code"],"expression" : ["code"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/cdisc-yes-no-vs|1.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/cdisc-yes-no-vs|1.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/cdisc-yes-no-vs|1.0.0-ballot: CodeSystem found: \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl| (from fhir.tx.support.r4#0.30.0)\"\r\n16 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/cdisc-yes-no-vs|1.0.0-ballot: Validate \"[#C49488 (\"\")]\" and infer system\r\n16 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/cdisc-yes-no-vs|1.0.0-ballot: Check \"#C49488\"\r\n16 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/cdisc-yes-no-vs|1.0.0-ballot: Inferred CodeSystem = \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl\"\r\n16 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/cdisc-yes-no-vs|1.0.0-ballot: CodeSystem found: http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl| (from fhir.tx.support.r4#0.30.0) for http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl\r\n32 16: 16ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/cdisc-yes-no-vs|1.0.0-ballot: Code \"C49488\" in concept list, but not found in http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl| (from fhir.tx.support.r4#0.30.0)\r\n"}]}

#73

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
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{"resourceType":"Parameters","parameter":[{"name":"inferSystem","valueBoolean":true},{"name":"code","valueCode":"C17998"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"cdisc-yes-no-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"brr"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ImplementationGuide/hl7.fhir.uv.pharmaceutical-research-protocol"}]}}],"url":"http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/cdisc-yes-no-vs","version":"1.0.0-ballot","name":"CDISCSDTMYesNoUnknownVS","title":"CDISC Yes No Unknown Not Applicable Value Set","status":"draft","experimental":false,"date":"2025-07-31T20:39:04+00:00","publisher":"HL7 International / Biomedical Research and Regulation","contact":[{"name":"HL7 International / Biomedical Research and Regulation","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/rcrim"},{"system":"email","value":"UDP@HL7Vulcan.org"}]}],"description":"Contains all values from C66742 - CDISC SDTM Yes No Unknown or Not Applicable Response Terminology","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"compose":{"include":[{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","concept":[{"code":"C49487","display":"No"},{"code":"C48660","display":"Not Applicable"},{"code":"C17998","display":"Unknown"},{"code":"C49488","display":"Yes"}]}]}}},{"name":"cache-id","valueId":"965d12b7-26e5-4742-8287-b739fab0f666"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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last-modified:Thu, 31 Jul 2025 20:40:43 GMT
pragma:no-cache
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x-request-id:233-7001885

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C17998"},{"name" : "display","valueString" : "Unknown"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/cdisc-yes-no-vs|1.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/cdisc-yes-no-vs|1.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/cdisc-yes-no-vs|1.0.0-ballot: CodeSystem found: \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl| (from fhir.tx.support.r4#0.30.0)\"\r\n16 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/cdisc-yes-no-vs|1.0.0-ballot: Validate \"[#C17998 (\"\")]\" and infer system\r\n31 15: 15ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/cdisc-yes-no-vs|1.0.0-ballot: Check \"#C17998\"\r\n31 0: 15ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/cdisc-yes-no-vs|1.0.0-ballot: Inferred CodeSystem = \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl\"\r\n31 0: 15ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/cdisc-yes-no-vs|1.0.0-ballot: CodeSystem found: http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl| (from fhir.tx.support.r4#0.30.0) for http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl\r\n31 0: 15ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/cdisc-yes-no-vs|1.0.0-ballot: Code \"C17998\" found in http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl| (from fhir.tx.support.r4#0.30.0)\r\n"}]}

#74

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C218515","display":"1.1 Protocol Synopsis"}},{"name":"displayLanguage","valueCode":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"965d12b7-26e5-4742-8287-b739fab0f666"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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date:Thu, 31 Jul 2025 20:40:43 GMT
last-modified:Thu, 31 Jul 2025 20:40:43 GMT
pragma:no-cache
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x-request-id:233-7001887

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C218515"},{"name" : "message","valueString" : "Unknown Code 'C218515' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C218515' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C218515 (\"1.1 Protocol Synopsis\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C218515\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl| (from fhir.tx.support.r4#0.30.0)\" (content = fragment)\r\n"}]}

#75

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
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{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C218515"}},{"name":"displayLanguage","valueCode":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-section-codes-vs--0","version":"1.0.0-ballot","status":"active","compose":{"include":[{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","concept":[{"code":"C218514","display":"1 PROTOCOL SUMMARY"},{"code":"C218515","display":"1.1 Protocol Synopsis"},{"code":"C218516","display":"1.1.1 Primary and Secondary Objectives and Estimands"},{"code":"C218517","display":"1.1.2 Overall Design"},{"code":"C218518","display":"1.2 Trial Schema"},{"code":"C218519","display":"1.3 Schedule of Activities"},{"code":"C218520","display":"2 INTRODUCTION"},{"code":"C218521","display":"2.1 Purpose of Trial"},{"code":"C218522","display":"2.2 Assessment of Risks and Benefits"},{"code":"C218523","display":"2.2.1 Risk Summary and Mitigation Strategy"},{"code":"C218524","display":"2.2.2 Benefit Summary"},{"code":"C218525","display":"2.2.3 Overall Risk-Benefit Assessment"},{"code":"C218526","display":"3 TRIAL OBJECTIVES AND ASSOCIATED ESTIMANDS"},{"code":"C218527","display":"3.1 Primary Objective(s) and Associated Estimand(s)"},{"code":"C218528","display":"3.1.1 Primary Objective"},{"code":"C218529","display":"3.2 Secondary Objective(s) and Associated Estimand(s)"},{"code":"C218530","display":"3.2.1 Secondary Objective"},{"code":"C218531","display":"3.3 Exploratory Objective(s)"},{"code":"C218532","display":"3.3.1 Exploratory Objective"},{"code":"C218533","display":"4 TRIAL DESIGN"},{"code":"C218534","display":"4.1 Description of Trial Design"},{"code":"C218535","display":"4.1.1 Stakeholder Input into Design"},{"code":"C218536","display":"4.2 Rationale for Trial Design"},{"code":"C218537","display":"4.2.1 Rationale for Estimand(s)"},{"code":"C218538","display":"4.2.2 Rationale for Intervention Model"},{"code":"C218539","display":"4.2.3 Rationale for Control Type"},{"code":"C218540","display":"4.2.4 Rationale for Trial Duration"},{"code":"C218541","display":"4.2.5 Rationale for Adaptive or Novel Trial Design"},{"code":"C218542","display":"4.2.6 Rationale for Interim Analysis"},{"code":"C218543","display":"4.2.7 Rationale for Other Trial Design Aspects"},{"code":"C218544","display":"4.3 Trial Stopping Rules"},{"code":"C218545","display":"4.4 Start of Trial and End of Trial"},{"code":"C218546","display":"4.5 Access to Trial Intervention After End of Trial"},{"code":"C218547","display":"5 TRIAL POPULATION"},{"code":"C218548","display":"5.1 Description of Trial Population and Rationale"},{"code":"C218549","display":"5.2 Inclusion Criteria"},{"code":"C218550","display":"5.3 Exclusion Criteria"},{"code":"C218551","display":"5.4 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Objective(s)"},{"code":"C218630","display":"10.4.1 Primary Objective"},{"code":"C218631","display":"10.4.1.1 Statistical Analysis Method"},{"code":"C218632","display":"10.4.1.2 Handling of Data in Relation to Primary Estimand(s)"},{"code":"C218633","display":"10.4.1.3 Handling of Missing Data in Relation to Primary Estimand(s)"},{"code":"C218634","display":"10.4.1.4 Sensitivity Analysis"},{"code":"C218635","display":"10.4.1.5 Supplementary Analysis"},{"code":"C218636","display":"10.5 Analyses Associated with the Secondary Objective(s)"},{"code":"C218637","display":"10.5.1 Secondary Objective"},{"code":"C218638","display":"10.5.1.1 Statistical Analysis Method"},{"code":"C218639","display":"10.5.1.2 Handling of Data in Relation to Secondary Estimand(s)"},{"code":"C218640","display":"10.5.1.3 Handling of Missing Data in Relation to Secondary Estimand(s)"},{"code":"C218641","display":"10.5.1.4 Sensitivity Analysis"},{"code":"C218642","display":"10.5.1.5 Supplementary Analysis"},{"code":"C218643","display":"10.6 Analyses Associated with the Exploratory Objective(s)"},{"code":"C218644","display":"10.7 Safety Analyses"},{"code":"C218645","display":"10.8 Other Analyses"},{"code":"C218646","display":"10.9 Interim Analyses"},{"code":"C218647","display":"10.10 Multiplicity Adjustments"},{"code":"C218648","display":"10.11 Sample Size Determination"},{"code":"C218649","display":"11 TRIAL OVERSIGHT AND OTHER GENERAL CONSIDERATIONS"},{"code":"C218650","display":"11.1 Regulatory and Ethical Considerations"},{"code":"C218651","display":"11.2 Trial Oversight"},{"code":"C218652","display":"11.2.1 Investigator Responsibilities"},{"code":"C218653","display":"11.2.2 Sponsor Responsibilities"},{"code":"C218654","display":"11.3 Informed Consent Process"},{"code":"C218655","display":"11.3.1 Informed Consent for Rescreening"},{"code":"C218656","display":"11.3.2 Informed Consent for Use of Remaining Samples in Exploratory Research"},{"code":"C218657","display":"11.4 Committees"},{"code":"C218658","display":"11.5 Insurance and Indemnity"},{"code":"C218659","display":"11.6 Risk-Based Quality Management"},{"code":"C218660","display":"11.7 Data Governance"},{"code":"C218661","display":"11.8 Data Protection"},{"code":"C218662","display":"11.9 Source Data"},{"code":"C218663","display":"11.10 Protocol Deviations"},{"code":"C218664","display":"11.11 Early Site Closure"},{"code":"C218665","display":"11.12 Data Dissemination"},{"code":"C218666","display":"12 APPENDIX: SUPPORTING DETAILS"},{"code":"C218667","display":"12.1 Clinical Laboratory Tests"},{"code":"C218668","display":"12.2 Country/Region-Specific Differences"},{"code":"C218669","display":"12.3 Prior Protocol Amendment(s)"},{"code":"C218670","display":"13 APPENDIX: GLOSSARY OF TERMS AND ABBREVIATIONS"},{"code":"C218671","display":"14 APPENDIX: REFERENCES"}]}]}}},{"name":"cache-id","valueId":"965d12b7-26e5-4742-8287-b739fab0f666"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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last-modified:Thu, 31 Jul 2025 20:40:44 GMT
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C218550"},{"name" : "message","valueString" : "The provided code 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C218550' was not found in the value set 'http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-section-codes-vs--0|1.0.0-ballot'; Unknown Code 'C218550' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C218550' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "The provided code 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C218550' was not found in the value set 'http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-section-codes-vs--0|1.0.0-ballot'"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n31 31: tx-op\r\n31 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-section-codes-vs--0|1.0.0-ballot: Analysing\r\n31 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-section-codes-vs--0|1.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n31 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-section-codes-vs--0|1.0.0-ballot: CodeSystem found: \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl| (from fhir.tx.support.r4#0.30.0)\"\r\n31 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-section-codes-vs--0|1.0.0-ballot: Validate \"[http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C218550 (\"\")]\"\r\n31 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-section-codes-vs--0|1.0.0-ballot: Check \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C218550\"\r\n31 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-section-codes-vs--0|1.0.0-ballot: CodeSystem found: http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl| (from fhir.tx.support.r4#0.30.0) for http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl\r\n47 16: 16ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-section-codes-vs--0|1.0.0-ballot: Code \"C218550\" in concept list, but not found in http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl| (from fhir.tx.support.r4#0.30.0)\r\n"}]}

#78

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C15602","display":"Phase 3"}},{"name":"displayLanguage","valueCode":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"965d12b7-26e5-4742-8287-b739fab0f666"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C15602"},{"name" : "message","valueString" : "Unknown Code 'C15602' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C15602' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C15602 (\"Phase 3\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C15602\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl| (from fhir.tx.support.r4#0.30.0)\" (content = fragment)\r\n"}]}

#79

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
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{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C15602"}},{"name":"displayLanguage","valueCode":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-phase-vs--0","version":"1.0.0-ballot","status":"active","compose":{"include":[{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","concept":[{"code":"C54721","display":"Early Phase 1"},{"code":"C15600","display":"Phase 1"},{"code":"C15693","display":"Phase 1/Phase 2"},{"code":"C198366","display":"Phase 1/Phase 2/Phase 3"},{"code":"C198367","display":"Phase 1/Phase 3"},{"code":"C217024","display":"Phase 2/Phase 3/Phase 4"},{"code":"C15601","display":"Phase 2"},{"code":"C15694","display":"Phase 2/Phase 3"},{"code":"C217025","display":"Phase 3/Phase 4"},{"code":"C15602","display":"Phase 3"},{"code":"C15603","display":"Phase 4"}]}]}}},{"name":"cache-id","valueId":"965d12b7-26e5-4742-8287-b739fab0f666"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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x-request-id:233-7001900

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C15602"},{"name" : "message","valueString" : "The provided code 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C15602' was not found in the value set 'http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-phase-vs--0|1.0.0-ballot'; Unknown Code 'C15602' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C15602' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "The provided code 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C15602' was not found in the value set 'http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-phase-vs--0|1.0.0-ballot'"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-phase-vs--0|1.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-phase-vs--0|1.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-phase-vs--0|1.0.0-ballot: CodeSystem found: \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl| (from fhir.tx.support.r4#0.30.0)\"\r\n0 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-phase-vs--0|1.0.0-ballot: Validate \"[http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C15602 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-phase-vs--0|1.0.0-ballot: Check \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C15602\"\r\n0 0: 0ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-phase-vs--0|1.0.0-ballot: CodeSystem found: http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl| (from fhir.tx.support.r4#0.30.0) for http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl\r\n16 16: 16ms http://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-phase-vs--0|1.0.0-ballot: Code \"C15602\" in concept list, but not found in http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl| (from fhir.tx.support.r4#0.30.0)\r\n"}]}

#80

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://snomed.info/sct","code":"1137328006","display":"Iatrogenic hypoglycaemia"}},{"name":"displayLanguage","valueCode":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"965d12b7-26e5-4742-8287-b739fab0f666"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "1137328006"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Iatrogenic hypoglycaemia"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#1137328006 (\"Iatrogenic hypoglycaemia\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#1137328006\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#81

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"965d12b7-26e5-4742-8287-b739fab0f666"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","concept":[{"code":"C49487","display":"No"},{"code":"C48660","display":"Not Applicable"},{"code":"C17998","display":"Unknown"},{"code":"C49488","display":"Yes"}]}]}}}]}

422
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date:Thu, 31 Jul 2025 20:41:01 GMT
server:nginx
x-request-id:233-7002040

{"resourceType" : "OperationOutcome","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>The code system definition for http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl is a fragment, so this expansion is not permitted unless the expansion parameter \"incomplete-ok\" has a value of \"true\"</p></div>"},"issue" : [{"severity" : "error","code" : "invalid","details" : {"text" : "The code system definition for http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl is a fragment, so this expansion is not permitted unless the expansion parameter \"incomplete-ok\" has a value of \"true\""}}]}

#82

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
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#83

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
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#84

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
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#85

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
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#86

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
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#87

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
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#90

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#91

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#92

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#93

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#95

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#96

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#97

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#98

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#99

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#100

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