Pharmaceutical Quality (Industry)
1.0.0 - STU1

Pharmaceutical Quality (Industry), published by HL7 International / Biomedical Research and Regulation. This guide is not an authorized publication; it is the continuous build for version 1.0.0 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/uv-dx-pq/ and changes regularly. See the Directory of published versions

## : Example: Bundle - Process Validation, product - XML Representation

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      <!--  Product Process Validation  -->
    <Bundle xmlns="http://hl7.org/fhir">
      <id value="bundle-product-process-validation-pq-ex1"/>
      <meta>
        <profile
                 value="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Bundle-product-process-validation-pq"/>
      </meta>
      <type value="collection"/>
      <entry>
        <fullUrl value="urn:uuid:2038e4c7-22b8-4c56-2d28-6c077648763f"/>
        <resource>
          <PlanDefinition>
            <!-- validationProtocol -->
            <id value="2038e4c7-22b8-4c56-2d28-6c077648763f"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="PlanDefinition_2038e4c7-22b8-4c56-2d28-6c077648763f"> </a><p><b>Generated Narrative: PlanDefinition</b><a name="2038e4c7-22b8-4c56-2d28-6c077648763f"> </a><a name="hc2038e4c7-22b8-4c56-2d28-6c077648763f"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource PlanDefinition &quot;2038e4c7-22b8-4c56-2d28-6c077648763f&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/PlanDefinition/2038e4c7-22b8-4c56-2d28-6c077648763f</code></p><p><b>title</b>: DP PROCESS VALIDATION</p><p><b>type</b>: Workflow Definition <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.0.0/CodeSystem-plan-definition-type.html">PlanDefinitionType</a>#workflow-definition; <a href="CodeSystem-pharmaceutical-plan-type.html">Pharmaceutical Plan Type Codes</a>#process-validation &quot;Process Validation&quot;)</span></p><p><b>status</b>: active</p><p><b>subject</b>: See on this page: MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5</p><p><b>description</b>: Pre-defined validation acceptance criteria were established based on manufacturing development data derived from process characterization studies...</p><blockquote><p><b>action</b></p><p><b>title</b>: Compounding Step</p><p><b>code</b>: Compounding Step <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-manufacturing-step.html">Manufacturing Step Codes</a>#compounding)</span></p><blockquote><p><b>action</b></p><p><b>title</b>: Compounding Steps</p><p><b>code</b>: Compounding <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote></blockquote></blockquote><blockquote><p><b>action</b></p><p><b>title</b>: Filling Steps</p><p><b>code</b>: Filling Step <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-manufacturing-step.html">Manufacturing Step Codes</a>#filling)</span></p><blockquote><p><b>action</b></p><p><b>title</b>: ???</p><p><b>code</b>: ??? <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote></blockquote></blockquote><blockquote><p><b>action</b></p><p><b>title</b>: Lyophilization Step</p><p><b>code</b>: Lyophilization Step <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-manufacturing-step.html">Manufacturing Step Codes</a>#lyophilization)</span></p><h3>Actions</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Definition[x]</b></td></tr><tr><td style="display: none">*</td><td>Conclusion <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></td><td><a href="http://example-server.com/fhir/ObservationDefinition/22525a3c-5034-448a-9c19-938ce1958424">http://example-server.com/fhir/ObservationDefinition/22525a3c-5034-448a-9c19-938ce1958424</a></td></tr><tr><td style="display: none">*</td><td>Test <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></td><td><a href="http://example-server.com/fhir/ObservationDefinition/64535a3c-5334-448a-9c29-938ce2958424">http://example-server.com/fhir/ObservationDefinition/64535a3c-5334-448a-9c29-938ce2958424</a></td></tr><tr><td style="display: none">*</td><td>Test <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></td><td><a href="http://example-server.com/fhir/ObservationDefinition/22e7e672-40a6-4036-3c1f-b8ba6a7d045e">http://example-server.com/fhir/ObservationDefinition/22e7e672-40a6-4036-3c1f-b8ba6a7d045e</a></td></tr><tr><td style="display: none">*</td><td>Test <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></td><td><a href="http://example-server.com/fhir/ObservationDefinition/32e29d22-5fcb-546e-24fd-52a4a4004467">http://example-server.com/fhir/ObservationDefinition/32e29d22-5fcb-546e-24fd-52a4a4004467</a></td></tr><tr><td style="display: none">*</td><td>Homogeneity <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></td><td><a href="http://example-server.com/fhir/ObservationDefinition/32e29d22-6fcb-546e-24fd-52a4a4004467">http://example-server.com/fhir/ObservationDefinition/32e29d22-6fcb-546e-24fd-52a4a4004467</a></td></tr><tr><td style="display: none">*</td><td>Homogeneity <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></td><td><a href="http://example-server.com/fhir/ObservationDefinition/32e29d32-6fcb-546e-24fd-52a4a4004467">http://example-server.com/fhir/ObservationDefinition/32e29d32-6fcb-546e-24fd-52a4a4004467</a></td></tr></table></blockquote><blockquote><p><b>action</b></p><p><b>title</b>: Release Step</p><p><b>code</b>: Release Step <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-manufacturing-step.html">Manufacturing Step Codes</a>#release)</span></p><blockquote><p><b>action</b></p><p><b>title</b>: ???</p><p><b>code</b>: ??? <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote></blockquote></blockquote></div>
            </text>
            <!-- http://example-server.com/fhir/PlanDefinition/2038e4c7-22b8-4c56-2d28-6c077648763f -->
            <url
                 value="http://example-server.com/fhir/PlanDefinition/2038e4c7-22b8-4c56-2d28-6c077648763f"/>
            <title value="DP PROCESS VALIDATION"/>
            <type>
              <coding>
                <system
                        value="http://terminology.hl7.org/CodeSystem/plan-definition-type"/>
                <code value="workflow-definition"/>
                <display value="Workflow Definition"/>
              </coding>
              <coding>
                <system
                        value="http://terminology.hl7.org/CodeSystem/pharmaceutical-plan-type"/>
                <code value="process-validation"/>
                <display value="Process Validation"/>
              </coding>
            </type>
            <status value="active"/>
            <subjectReference>
              <!-- MedicinalProductDefinition/medicinalproductdefinition-drug-product-pq-ex1 -->
              <reference
                         value="MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"/>
            </subjectReference>
            <description
                         value="Pre-defined validation acceptance criteria were established based on manufacturing development data derived from process characterization studies..."/>
            <action>
              <title value="Compounding Step"/>
              <!-- text value="Overall set of actions"/ -->
              <code>
                <coding>
                  <system
                          value="http://terminology.hl7.org/CodeSystem/manufacturing-step"/>
                  <code value="compounding"/>
                  <display value="Compounding Step"/>
                </coding>
              </code>
              <action>
                <!--  this level is not really needed here, could remove. But in the case where there are different timings, it is needed, so it is here for consistency  -->
                <title value="Compounding Steps"/>
                <code>
                  <text value="Compounding"/>
                </code>
                <action>
                  <code>
                    <text value="Test"/>
                  </code>
                  <!-- ObservationDefinition/compoundingpHPre -->
                  <definitionCanonical
                                       value="http://example-server.com/fhir/ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e72"/>
                </action>
                <action>
                  <code>
                    <text value="Test"/>
                  </code>
                  <!-- ObservationDefinition/compoundingpHPost -->
                  <definitionCanonical
                                       value="http://example-server.com/fhir/ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e73"/>
                </action>
                <action>
                  <code>
                    <text value="Test"/>
                  </code>
                  <!-- ObservationDefinition/compoundingAssayPre -->
                  <definitionCanonical
                                       value="http://example-server.com/fhir/ObservationDefinition/fd17b5d5-9fe1-91c2-2d06-47cb5b295e72"/>
                </action>
                <action>
                  <code>
                    <text value="Test"/>
                  </code>
                  <!-- ObservationDefinition/compoundingAssayPost -->
                  <definitionCanonical
                                       value="http://example-server.com/fhir/ObservationDefinition/fd17b5d5-9fe1-91c2-2d06-47cb5b295e73"/>
                </action>
              </action>
            </action>
            <action>
              <title value="Filling Steps"/>
              <code>
                <coding>
                  <system
                          value="http://terminology.hl7.org/CodeSystem/manufacturing-step"/>
                  <code value="filling"/>
                  <display value="Filling Step"/>
                </coding>
              </code>
              <action>
                <title value="???"/>
                <code>
                  <text value="???"/>
                </code>
                <action>
                  <code>
                    <text value="Conclusion"/>
                  </code>
                  <!-- ObservationDefinition/conclusion -->
                  <definitionCanonical
                                       value="http://example-server.com/fhir/ObservationDefinition/22515a3c-5034-448a-9c19-938ce1958424"/>
                </action>
                <action>
                  <code>
                    <text value="Test"/>
                  </code>
                  <!-- ObservationDefinition/TAMC -->
                  <definitionCanonical
                                       value="http://example-server.com/fhir/ObservationDefinition/64505a3c-5034-448a-9c19-938ce1958424"/>
                </action>
                <action>
                  <code>
                    <text value="Test"/>
                  </code>
                  <!-- ObservationDefinition/TYMC -->
                  <definitionCanonical
                                       value="http://example-server.com/fhir/ObservationDefinition/64515a3c-5034-448a-9c19-938ce1958424"/>
                </action>
                <action>
                  <code>
                    <text value="Test"/>
                  </code>
                  <!-- ObservationDefinition/FillWeightAverage -->
                  <definitionCanonical
                                       value="http://example-server.com/fhir/ObservationDefinition/64515a3c-5134-448a-9c19-938ce1958424"/>
                </action>
                <action>
                  <code>
                    <text value="Test"/>
                  </code>
                  <!-- ObservationDefinition/FillWeightTarget -->
                  <definitionCanonical
                                       value="http://example-server.com/fhir/ObservationDefinition/64525a3c-5134-448a-9c19-938ce1958424"/>
                </action>
                <action>
                  <code>
                    <text value="Test"/>
                  </code>
                  <!-- ObservationDefinition/FillWeightAverageFromTarget -->
                  <definitionCanonical
                                       value="http://example-server.com/fhir/ObservationDefinition/64515a3c-5134-448a-9c29-938ce1958424"/>
                </action>
                <action>
                  <code>
                    <text value="Test"/>
                  </code>
                  <!-- ObservationDefinition/HoldTimeFiltrationToFilling -->
                  <definitionCanonical
                                       value="http://example-server.com/fhir/ObservationDefinition/64515a3c-5234-448a-9c29-938ce1958424"/>
                </action>
                <action>
                  <code>
                    <text value="Test"/>
                  </code>
                  <!-- ObservationDefinition/HoldTimeFilling -->
                  <definitionCanonical
                                       value="http://example-server.com/fhir/ObservationDefinition/64515a3c-5334-448a-9c29-938ce1958424"/>
                </action>
                <action>
                  <code>
                    <text value="Test"/>
                  </code>
                  <!-- ObservationDefinition/FilterIntegrity -->
                  <definitionCanonical
                                       value="http://example-server.com/fhir/ObservationDefinition/64535a3c-5334-448a-9c29-938ce1958424"/>
                </action>
              </action>
            </action>
            <action>
              <title value="Lyophilization Step"/>
              <code>
                <coding>
                  <system
                          value="http://terminology.hl7.org/CodeSystem/manufacturing-step"/>
                  <code value="lyophilization"/>
                  <display value="Lyophilization Step"/>
                </coding>
              </code>
              <action>
                <code>
                  <text value="Conclusion"/>
                </code>
                <!-- ObservationDefinition/LyophilizationConclusion -->
                <definitionCanonical
                                     value="http://example-server.com/fhir/ObservationDefinition/22525a3c-5034-448a-9c19-938ce1958424"/>
              </action>
              <action>
                <code>
                  <text value="Test"/>
                </code>
                <!-- ObservationDefinition/LyophilizerNumber -->
                <definitionCanonical
                                     value="http://example-server.com/fhir/ObservationDefinition/64535a3c-5334-448a-9c29-938ce2958424"/>
              </action>
              <action>
                <code>
                  <text value="Test"/>
                </code>
                <!-- ObservationDefinition/LyophilizationAssay -->
                <definitionCanonical
                                     value="http://example-server.com/fhir/ObservationDefinition/22e7e672-40a6-4036-3c1f-b8ba6a7d045e"/>
              </action>
              <action>
                <code>
                  <text value="Test"/>
                </code>
                <!-- ObservationDefinition/LyophilizationWater -->
                <definitionCanonical
                                     value="http://example-server.com/fhir/ObservationDefinition/32e29d22-5fcb-546e-24fd-52a4a4004467"/>
              </action>
              <action>
                <code>
                  <text value="Homogeneity"/>
                </code>
                <!-- ObservationDefinition/LyophilizationWaterHomogeneity -->
                <definitionCanonical
                                     value="http://example-server.com/fhir/ObservationDefinition/32e29d22-6fcb-546e-24fd-52a4a4004467"/>
              </action>
              <action>
                <code>
                  <text value="Homogeneity"/>
                </code>
                <!-- ObservationDefinition/LyophilizationAssayHomogeneity -->
                <definitionCanonical
                                     value="http://example-server.com/fhir/ObservationDefinition/32e29d32-6fcb-546e-24fd-52a4a4004467"/>
              </action>
            </action>
            <action>
              <title value="Release Step"/>
              <!-- text value="Overall set of actions"/ -->
              <code>
                <coding>
                  <system
                          value="http://terminology.hl7.org/CodeSystem/manufacturing-step"/>
                  <code value="release"/>
                  <display value="Release Step"/>
                </coding>
              </code>
              <action>
                <title value="???"/>
                <code>
                  <text value="???"/>
                </code>
                <action>
                  <code>
                    <text value="Test"/>
                  </code>
                  <!-- ObservationDefinition/AppearanceProduct -->
                  <definitionCanonical
                                       value="http://example-server.com/fhir/ObservationDefinition/fc07b5d5-9fe1-92c2-2d06-47cb5b295e72"/>
                </action>
                <action>
                  <code>
                    <text value="Test"/>
                  </code>
                  <!-- ObservationDefinition/AppearanceLyophilized -->
                  <definitionCanonical
                                       value="http://example-server.com/fhir/ObservationDefinition/fc07b5d5-9fe1-92c3-2d16-47cb5b295e72"/>
                </action>
                <action>
                  <code>
                    <text value="Test"/>
                  </code>
                  <!-- ObservationDefinition/AppearanceReconstituted -->
                  <definitionCanonical
                                       value="http://example-server.com/fhir/ObservationDefinition/fc07b5d5-9fe1-92c3-2d06-47cb5b295e72"/>
                </action>
                <action>
                  <code>
                    <text value="Test"/>
                  </code>
                  <!-- ObservationDefinition/Identification -->
                  <definitionCanonical
                                       value="http://example-server.com/fhir/ObservationDefinition/3b0e878e-4bc9-8864-862f-e28b21233e8d"/>
                </action>
                <action>
                  <code>
                    <text value="Test"/>
                  </code>
                  <!-- ObservationDefinition/Assay -->
                  <definitionCanonical
                                       value="http://example-server.com/fhir/ObservationDefinition/12e7e672-40a6-4036-3c1f-b8ba6a7d045e"/>
                </action>
                <action>
                  <code>
                    <text value="Test"/>
                  </code>
                  <!-- ObservationDefinition/Degradation -->
                  <definitionCanonical
                                       value="http://example-server.com/fhir/ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf"/>
                </action>
                <action>
                  <code>
                    <text value="Test"/>
                  </code>
                  <!-- ObservationDefinition/Water -->
                  <definitionCanonical
                                       value="http://example-server.com/fhir/ObservationDefinition/31e29d22-5fcb-546e-24fd-52a4a4004467"/>
                </action>
                <action>
                  <code>
                    <text value="Test"/>
                  </code>
                  <!-- ObservationDefinition/UniformityUSP -->
                  <definitionCanonical
                                       value="http://example-server.com/fhir/ObservationDefinition/ef17cff1-6586-a5a4-9168-2602140548d7"/>
                </action>
                <action>
                  <code>
                    <text value="Test"/>
                  </code>
                  <!-- ObservationDefinition/UniformityAcceptance -->
                  <definitionCanonical
                                       value="http://example-server.com/fhir/ObservationDefinition/ef17cff1-6586-a5a4-9168-2602140548d8"/>
                </action>
                <action>
                  <code>
                    <text value="Test"/>
                  </code>
                  <!-- ObservationDefinition/releasepH -->
                  <definitionCanonical
                                       value="http://example-server.com/fhir/ObservationDefinition/fc17b5d6-9fe1-91c2-2d06-47cb5b295e72"/>
                </action>
              </action>
            </action>
          </PlanDefinition>
        </resource>
      </entry>
      <!--  compounding step  -->
      <entry>
        <fullUrl value="urn:uuid:fc17b5d5-9fe1-91c2-2d06-47cb5b295e72"/>
        <resource>
          <ObservationDefinition>
            <!-- compoundingpHPre -->
            <id value="fc17b5d5-9fe1-91c2-2d06-47cb5b295e72"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="ObservationDefinition_fc17b5d5-9fe1-91c2-2d06-47cb5b295e72"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name="fc17b5d5-9fe1-91c2-2d06-47cb5b295e72"> </a><a name="hcfc17b5d5-9fe1-91c2-2d06-47cb5b295e72"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition &quot;fc17b5d5-9fe1-91c2-2d06-47cb5b295e72&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e72</code></p><p><b>title</b>: pH (adjustment of pre-clarification bulk solution)</p><p><b>status</b>: active</p><p><b>code</b>: pH (adjustment of pre-clarification bulk solution) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#pH (adjustment of pre-clarification bulk solution))</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td>6.9-7.1 pH</td></tr></table></div>
            </text>
            <!-- http://example-server.com/fhir/ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e72 -->
            <url
                 value="http://example-server.com/fhir/ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e72"/>
            <title value="pH (adjustment of pre-clarification bulk solution)"/>
            <status value="active"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="pH (adjustment of pre-clarification bulk solution)"/>
                <display
                         value="pH (adjustment of pre-clarification bulk solution)"/>
              </coding>
              <text value="pH (adjustment of pre-clarification bulk solution)"/>
            </code>
            <qualifiedValue>
              <range>
                <low>
                  <value value="6.9"/>
                  <unit value="pH"/>
                  <system value="http://unitsofmeasure.org"/>
                  <code value="pH"/>
                </low>
                <high>
                  <value value="7.1"/>
                  <unit value="pH"/>
                  <system value="http://unitsofmeasure.org"/>
                  <code value="pH"/>
                </high>
              </range>
            </qualifiedValue>
          </ObservationDefinition>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:fc17b5d5-9fe1-91c2-2d06-47cb5b295e73"/>
        <resource>
          <ObservationDefinition>
            <!-- compoundingpHPost -->
            <id value="fc17b5d5-9fe1-91c2-2d06-47cb5b295e73"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="ObservationDefinition_fc17b5d5-9fe1-91c2-2d06-47cb5b295e73"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name="fc17b5d5-9fe1-91c2-2d06-47cb5b295e73"> </a><a name="hcfc17b5d5-9fe1-91c2-2d06-47cb5b295e73"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition &quot;fc17b5d5-9fe1-91c2-2d06-47cb5b295e73&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e73</code></p><p><b>title</b>: pH (post-dilution bulk solution)</p><p><b>status</b>: active</p><p><b>code</b>: pH (post-dilution bulk solution) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#pH (post-dilution bulk solution))</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td>7.0-7.1 pH</td></tr></table></div>
            </text>
            <!-- http://example-server.com/fhir/ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e73 -->
            <url
                 value="http://example-server.com/fhir/ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e73"/>
            <title value="pH (post-dilution bulk solution)"/>
            <status value="active"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="pH (post-dilution bulk solution)"/>
                <display value="pH (post-dilution bulk solution)"/>
              </coding>
              <text value="pH (post-dilution bulk solution)"/>
            </code>
            <qualifiedValue>
              <range>
                <low>
                  <value value="7.0"/>
                  <unit value="pH"/>
                  <system value="http://unitsofmeasure.org"/>
                  <code value="pH"/>
                </low>
                <high>
                  <value value="7.1"/>
                  <unit value="pH"/>
                  <system value="http://unitsofmeasure.org"/>
                  <code value="pH"/>
                </high>
              </range>
            </qualifiedValue>
          </ObservationDefinition>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:fd17b5d5-9fe1-91c2-2d06-47cb5b295e72"/>
        <resource>
          <ObservationDefinition>
            <!-- compoundingAssayPre -->
            <id value="fd17b5d5-9fe1-91c2-2d06-47cb5b295e72"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="ObservationDefinition_fd17b5d5-9fe1-91c2-2d06-47cb5b295e72"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name="fd17b5d5-9fe1-91c2-2d06-47cb5b295e72"> </a><a name="hcfd17b5d5-9fe1-91c2-2d06-47cb5b295e72"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition &quot;fd17b5d5-9fe1-91c2-2d06-47cb5b295e72&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/fd17b5d5-9fe1-91c2-2d06-47cb5b295e72</code></p><p><b>title</b>: Assay (pre-clarification filtration) (mg/mL)</p><p><b>status</b>: active</p><p><b>code</b>: Assay (pre-clarification filtration) (mg/mL) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#Assay (pre-clarification filtration) (mg/mL))</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td>22-? mg/mL</td></tr></table></div>
            </text>
            <!-- http://example-server.com/fhir/ObservationDefinition/fd17b5d5-9fe1-91c2-2d06-47cb5b295e72 -->
            <url
                 value="http://example-server.com/fhir/ObservationDefinition/fd17b5d5-9fe1-91c2-2d06-47cb5b295e72"/>
            <title value="Assay (pre-clarification filtration) (mg/mL)"/>
            <status value="active"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="Assay (pre-clarification filtration) (mg/mL)"/>
                <display value="Assay (pre-clarification filtration) (mg/mL)"/>
              </coding>
              <text value="Assay (pre-clarification filtration) (mg/mL)"/>
            </code>
            <qualifiedValue>
              <range>
                <!--  todo correct this and the others  -->
                <low>
                  <value value="22"/>
                  <unit value="mg/mL"/>
                  <system value="http://unitsofmeasure.org"/>
                  <code value="mg/mL"/>
                </low>
              </range>
            </qualifiedValue>
          </ObservationDefinition>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:fd17b5d5-9fe1-91c2-2d06-47cb5b295e73"/>
        <resource>
          <ObservationDefinition>
            <!-- compoundingAssayPost -->
            <id value="fd17b5d5-9fe1-91c2-2d06-47cb5b295e73"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="ObservationDefinition_fd17b5d5-9fe1-91c2-2d06-47cb5b295e73"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name="fd17b5d5-9fe1-91c2-2d06-47cb5b295e73"> </a><a name="hcfd17b5d5-9fe1-91c2-2d06-47cb5b295e73"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition &quot;fd17b5d5-9fe1-91c2-2d06-47cb5b295e73&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/fd17b5d5-9fe1-91c2-2d06-47cb5b295e73</code></p><p><b>title</b>: Assay (Post dilution bulk solution) (mg/mL)</p><p><b>status</b>: active</p><p><b>code</b>: Assay (Post dilution bulk solution) (mg/mL) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#Assay (Post dilution bulk solution) (mg/mL))</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td>20-21 mg/mL</td></tr></table></div>
            </text>
            <!-- http://example-server.com/fhir/ObservationDefinition/fd17b5d5-9fe1-91c2-2d06-47cb5b295e73 -->
            <url
                 value="http://example-server.com/fhir/ObservationDefinition/fd17b5d5-9fe1-91c2-2d06-47cb5b295e73"/>
            <title value="Assay (Post dilution bulk solution) (mg/mL)"/>
            <status value="active"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="Assay (Post dilution bulk solution) (mg/mL)"/>
                <display value="Assay (Post dilution bulk solution) (mg/mL)"/>
              </coding>
              <text value="Assay (Post dilution bulk solution) (mg/mL)"/>
            </code>
            <qualifiedValue>
              <range>
                <!--  todo correct this  -->
                <low>
                  <value value="20"/>
                  <unit value="mg/mL"/>
                  <system value="http://unitsofmeasure.org"/>
                  <code value="mg/mL"/>
                </low>
                <!--  todo correct this  -->
                <high>
                  <value value="21"/>
                  <unit value="mg/mL"/>
                  <system value="http://unitsofmeasure.org"/>
                  <code value="mg/mL"/>
                </high>
              </range>
            </qualifiedValue>
          </ObservationDefinition>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:fc07b5d5-9fe1-92c2-2d06-47cb5b295e72"/>
        <resource>
          <ObservationDefinition>
            <!-- AppearanceProduct -->
            <id value="fc07b5d5-9fe1-92c2-2d06-47cb5b295e72"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="ObservationDefinition_fc07b5d5-9fe1-92c2-2d06-47cb5b295e72"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name="fc07b5d5-9fe1-92c2-2d06-47cb5b295e72"> </a><a name="hcfc07b5d5-9fe1-92c2-2d06-47cb5b295e72"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition &quot;fc07b5d5-9fe1-92c2-2d06-47cb5b295e72&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/fc07b5d5-9fe1-92c2-2d06-47cb5b295e72</code></p><p><b>title</b>: Appearance (Product Container, visual)</p><p><b>status</b>: active</p><p><b>code</b>: Appearance (Product Container, visual) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#Appearance (Product Container, visual))</span></p><p><b>method</b>: Visual inspection <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Extension</b></td></tr><tr><td style="display: none">*</td><td/></tr></table></div>
            </text>
            <!-- http://example-server.com/fhir/ObservationDefinition/fc07b5d5-9fe1-92c2-2d06-47cb5b295e72 -->
            <url
                 value="http://example-server.com/fhir/ObservationDefinition/fc07b5d5-9fe1-92c2-2d06-47cb5b295e72"/>
            <title value="Appearance (Product Container, visual)"/>
            <status value="active"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="Appearance (Product Container, visual)"/>
                <display value="Appearance (Product Container, visual)"/>
              </coding>
              <text value="Appearance (Product Container, visual)"/>
            </code>
            <method>
              <text value="Visual inspection"/>
            </method>
            <qualifiedValue>
              <extension
                         url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-text-pq">
                <valueString
                             value="1)  Clear glass vial sealed with a gray rubber stopper and a flip off overseal 2)  No visible damage or breach of vial container or closure"/>
              </extension>
            </qualifiedValue>
          </ObservationDefinition>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:fc07b5d5-9fe1-92c3-2d16-47cb5b295e72"/>
        <resource>
          <ObservationDefinition>
            <!-- AppearanceLyophilized -->
            <id value="fc07b5d5-9fe1-92c3-2d16-47cb5b295e72"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="ObservationDefinition_fc07b5d5-9fe1-92c3-2d16-47cb5b295e72"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name="fc07b5d5-9fe1-92c3-2d16-47cb5b295e72"> </a><a name="hcfc07b5d5-9fe1-92c3-2d16-47cb5b295e72"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition &quot;fc07b5d5-9fe1-92c3-2d16-47cb5b295e72&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/fc07b5d5-9fe1-92c3-2d16-47cb5b295e72</code></p><p><b>title</b>: Appearance (Lyophilized, Visual)</p><p><b>status</b>: active</p><p><b>code</b>: Appearance (Lyophilized, Visual) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#Appearance (Lyophilized, Visual))</span></p><p><b>method</b>: Visual inspection <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Extension</b></td></tr><tr><td style="display: none">*</td><td/></tr></table></div>
            </text>
            <!-- http://example-server.com/fhir/ObservationDefinition/fc07b5d5-9fe1-92c3-2d16-47cb5b295e72 -->
            <url
                 value="http://example-server.com/fhir/ObservationDefinition/fc07b5d5-9fe1-92c3-2d16-47cb5b295e72"/>
            <title value="Appearance (Lyophilized, Visual)"/>
            <status value="active"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="Appearance (Lyophilized, Visual)"/>
                <display value="Appearance (Lyophilized, Visual)"/>
              </coding>
              <text value="Appearance (Lyophilized, Visual)"/>
            </code>
            <method>
              <text value="Visual inspection"/>
            </method>
            <qualifiedValue>
              <extension
                         url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-text-pq">
                <valueString
                             value="White to off white cake or powder, essentially free from evidence of contamination with no visible foreign particulates"/>
              </extension>
            </qualifiedValue>
          </ObservationDefinition>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:fc07b5d5-9fe1-92c3-2d06-47cb5b295e72"/>
        <resource>
          <ObservationDefinition>
            <!-- AppearanceReconstituted -->
            <id value="fc07b5d5-9fe1-92c3-2d06-47cb5b295e72"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="ObservationDefinition_fc07b5d5-9fe1-92c3-2d06-47cb5b295e72"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name="fc07b5d5-9fe1-92c3-2d06-47cb5b295e72"> </a><a name="hcfc07b5d5-9fe1-92c3-2d06-47cb5b295e72"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition &quot;fc07b5d5-9fe1-92c3-2d06-47cb5b295e72&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/fc07b5d5-9fe1-92c3-2d06-47cb5b295e72</code></p><p><b>title</b>: Appearance (Reconstituted, Visual)</p><p><b>status</b>: active</p><p><b>code</b>: Appearance (Reconstituted, Visual) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#Appearance (Reconstituted, Visual))</span></p><p><b>method</b>: Visual inspection <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Extension</b></td></tr><tr><td style="display: none">*</td><td/></tr></table></div>
            </text>
            <!-- http://example-server.com/fhir/ObservationDefinition/fc07b5d5-9fe1-92c3-2d06-47cb5b295e72 -->
            <url
                 value="http://example-server.com/fhir/ObservationDefinition/fc07b5d5-9fe1-92c3-2d06-47cb5b295e72"/>
            <title value="Appearance (Reconstituted, Visual)"/>
            <status value="active"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="Appearance (Reconstituted, Visual)"/>
                <display value="Appearance (Reconstituted, Visual)"/>
              </coding>
              <text value="Appearance (Reconstituted, Visual)"/>
            </code>
            <method>
              <text value="Visual inspection"/>
            </method>
            <qualifiedValue>
              <extension
                         url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-text-pq">
                <valueString
                             value="Clear, colorless to slightly yellow solution, essentially free of visible particulates"/>
              </extension>
            </qualifiedValue>
          </ObservationDefinition>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:3b0e878e-4bc9-8864-862f-e28b21233e8d"/>
        <resource>
          <ObservationDefinition>
            <!-- Identification -->
            <id value="3b0e878e-4bc9-8864-862f-e28b21233e8d"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="ObservationDefinition_3b0e878e-4bc9-8864-862f-e28b21233e8d"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name="3b0e878e-4bc9-8864-862f-e28b21233e8d"> </a><a name="hc3b0e878e-4bc9-8864-862f-e28b21233e8d"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition &quot;3b0e878e-4bc9-8864-862f-e28b21233e8d&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/3b0e878e-4bc9-8864-862f-e28b21233e8d</code></p><p><b>title</b>: Identification</p><p><b>status</b>: active</p><p><b>code</b>: Identification <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#IDT)</span></p><p><b>method</b>: ID by UHPLC <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Extension</b></td></tr><tr><td style="display: none">*</td><td/></tr></table></div>
            </text>
            <!-- http://example-server.com/fhir/ObservationDefinition/3b0e878e-4bc9-8864-862f-e28b21233e8d -->
            <url
                 value="http://example-server.com/fhir/ObservationDefinition/3b0e878e-4bc9-8864-862f-e28b21233e8d"/>
            <title value="Identification"/>
            <status value="active"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="IDT"/>
                <display value="Identification"/>
              </coding>
              <text value="Identification"/>
            </code>
            <method>
              <text value="ID by UHPLC"/>
            </method>
            <qualifiedValue>
              <extension
                         url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-text-pq">
                <valueString
                             value="Consistent with the retention time and UV spectrum of the reference standard"/>
              </extension>
            </qualifiedValue>
          </ObservationDefinition>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:12e7e672-40a6-4036-3c1f-b8ba6a7d045e"/>
        <resource>
          <ObservationDefinition>
            <!-- Assay -->
            <id value="12e7e672-40a6-4036-3c1f-b8ba6a7d045e"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="ObservationDefinition_12e7e672-40a6-4036-3c1f-b8ba6a7d045e"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name="12e7e672-40a6-4036-3c1f-b8ba6a7d045e"> </a><a name="hc12e7e672-40a6-4036-3c1f-b8ba6a7d045e"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition &quot;12e7e672-40a6-4036-3c1f-b8ba6a7d045e&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/12e7e672-40a6-4036-3c1f-b8ba6a7d045e</code></p><p><b>title</b>: Assay</p><p><b>status</b>: active</p><p><b>code</b>: Assay <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#ASSAY)</span></p><p><b>method</b>: Assay by UHPLC <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Extension</b></td></tr><tr><td style="display: none">*</td><td/></tr></table></div>
            </text>
            <!-- http://example-server.com/fhir/ObservationDefinition/12e7e672-40a6-4036-3c1f-b8ba6a7d045e -->
            <url
                 value="http://example-server.com/fhir/ObservationDefinition/12e7e672-40a6-4036-3c1f-b8ba6a7d045e"/>
            <title value="Assay"/>
            <status value="active"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="ASSAY"/>
                <display value="Assay"/>
              </coding>
              <text value="Assay"/>
            </code>
            <method>
              <text value="Assay by UHPLC"/>
            </method>
            <qualifiedValue>
              <extension
                         url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-text-pq">
                <valueString value="95% to 105% of label claim"/>
              </extension>
            </qualifiedValue>
          </ObservationDefinition>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:8bdea820-4197-7c7d-0990-7be06bf78aaf"/>
        <resource>
          <ObservationDefinition>
            <!-- Degradation -->
            <id value="8bdea820-4197-7c7d-0990-7be06bf78aaf"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="ObservationDefinition_8bdea820-4197-7c7d-0990-7be06bf78aaf"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name="8bdea820-4197-7c7d-0990-7be06bf78aaf"> </a><a name="hc8bdea820-4197-7c7d-0990-7be06bf78aaf"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition &quot;8bdea820-4197-7c7d-0990-7be06bf78aaf&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf</code></p><p><b>title</b>: Degradation Products</p><p><b>status</b>: active</p><p><b>code</b>: Degradation Products <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#DGP)</span></p><p><b>method</b>: Degradation products by UHPLC <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: Impurity 1 <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><p><b>range</b>: ?-0.2</p></blockquote><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: Impurity 2 <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><p><b>range</b>: ?-0.3</p></blockquote><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: Impurity 3 <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><p><b>range</b>: ?-0.3</p></blockquote><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: Individual unspecified degradation products <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><p><b>range</b>: ?-0.2</p></blockquote><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: Total degradation products <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><p><b>range</b>: ?-1.4</p></blockquote><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td></tr><tr><td style="display: none">*</td><td>Impurity <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#IMP)</span></td></tr></table></div>
            </text>
            <!-- http://example-server.com/fhir/ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf -->
            <url
                 value="http://example-server.com/fhir/ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf"/>
            <title value="Degradation Products"/>
            <status value="active"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="DGP"/>
                <display value="Degradation Products"/>
              </coding>
            </code>
            <method>
              <text value="Degradation products by UHPLC"/>
            </method>
            <qualifiedValue>
              <appliesTo>
                <!--  could be a code  -->
                <text value="Impurity 1"/>
              </appliesTo>
              <range>
                <high>
                  <value value="0.2"/>
                  <unit value="% w/w"/>
                  <system value="http://unitsofmeasure.org"/>
                  <code value="%"/>
                </high>
              </range>
            </qualifiedValue>
            <qualifiedValue>
              <appliesTo>
                <text value="Impurity 2"/>
              </appliesTo>
              <range>
                <high>
                  <value value="0.3"/>
                  <unit value="% w/w"/>
                  <system value="http://unitsofmeasure.org"/>
                  <code value="%"/>
                </high>
              </range>
            </qualifiedValue>
            <qualifiedValue>
              <appliesTo>
                <text value="Impurity 3"/>
              </appliesTo>
              <range>
                <high>
                  <value value="0.3"/>
                  <unit value="% w/w"/>
                  <system value="http://unitsofmeasure.org"/>
                  <code value="%"/>
                </high>
              </range>
            </qualifiedValue>
            <qualifiedValue>
              <appliesTo>
                <text value="Individual unspecified degradation products"/>
              </appliesTo>
              <range>
                <high>
                  <value value="0.2"/>
                  <unit value="% w/w"/>
                  <system value="http://unitsofmeasure.org"/>
                  <code value="%"/>
                </high>
              </range>
            </qualifiedValue>
            <qualifiedValue>
              <appliesTo>
                <text value="Total degradation products"/>
              </appliesTo>
              <range>
                <high>
                  <value value="1.4"/>
                  <unit value="% w/w"/>
                  <system value="http://unitsofmeasure.org"/>
                  <code value="%"/>
                </high>
              </range>
            </qualifiedValue>
            <component>
              <!--  are expected to have a component that says what impurity this one is  -->
              <code>
                <coding>
                  <system
                          value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                  <code value="IMP"/>
                  <display value="Impurity"/>
                </coding>
              </code>
            </component>
          </ObservationDefinition>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:31e29d22-5fcb-546e-24fd-52a4a4004467"/>
        <resource>
          <ObservationDefinition>
            <!-- Water -->
            <id value="31e29d22-5fcb-546e-24fd-52a4a4004467"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="ObservationDefinition_31e29d22-5fcb-546e-24fd-52a4a4004467"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name="31e29d22-5fcb-546e-24fd-52a4a4004467"> </a><a name="hc31e29d22-5fcb-546e-24fd-52a4a4004467"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition &quot;31e29d22-5fcb-546e-24fd-52a4a4004467&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/31e29d22-5fcb-546e-24fd-52a4a4004467</code></p><p><b>title</b>: Water Content</p><p><b>status</b>: active</p><p><b>code</b>: Water Content <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#WaterContent)</span></p><p><b>method</b>: USP &lt;921&gt; <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td>?-1.0</td></tr></table></div>
            </text>
            <!-- http://example-server.com/fhir/ObservationDefinition/31e29d22-5fcb-546e-24fd-52a4a4004467 -->
            <url
                 value="http://example-server.com/fhir/ObservationDefinition/31e29d22-5fcb-546e-24fd-52a4a4004467"/>
            <title value="Water Content"/>
            <status value="active"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="WaterContent"/>
                <display value="Water Content"/>
              </coding>
              <text value="Water Content"/>
            </code>
            <method>
              <text value="USP &lt;921&gt;"/>
            </method>
            <qualifiedValue>
              <range>
                <high>
                  <value value="1.0"/>
                  <unit value="% w/w"/>
                  <system value="http://unitsofmeasure.org"/>
                  <code value="%"/>
                </high>
              </range>
            </qualifiedValue>
          </ObservationDefinition>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:32e29d22-5fcb-546e-24fd-52a4a4004467"/>
        <resource>
          <ObservationDefinition>
            <!-- LyophilizationWater -->
            <id value="32e29d22-5fcb-546e-24fd-52a4a4004467"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="ObservationDefinition_32e29d22-5fcb-546e-24fd-52a4a4004467"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name="32e29d22-5fcb-546e-24fd-52a4a4004467"> </a><a name="hc32e29d22-5fcb-546e-24fd-52a4a4004467"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition &quot;32e29d22-5fcb-546e-24fd-52a4a4004467&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/32e29d22-5fcb-546e-24fd-52a4a4004467</code></p><p><b>title</b>: Water Content</p><p><b>status</b>: active</p><p><b>code</b>: Water Content <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#WaterContent)</span></p><p><b>method</b>: USP &lt;921&gt; <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td>?-1.2</td></tr></table></div>
            </text>
            <!-- http://example-server.com/fhir/ObservationDefinition/32e29d22-5fcb-546e-24fd-52a4a4004467 -->
            <url
                 value="http://example-server.com/fhir/ObservationDefinition/32e29d22-5fcb-546e-24fd-52a4a4004467"/>
            <title value="Water Content"/>
            <status value="active"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="WaterContent"/>
                <display value="Water Content"/>
              </coding>
              <text value="Water Content"/>
            </code>
            <method>
              <text value="USP &lt;921&gt;"/>
            </method>
            <qualifiedValue>
              <range>
                <high>
                  <value value="1.2"/>
                  <unit value="% w/w"/>
                  <system value="http://unitsofmeasure.org"/>
                  <code value="%"/>
                </high>
              </range>
            </qualifiedValue>
          </ObservationDefinition>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:32e29d22-6fcb-546e-24fd-52a4a4004467"/>
        <resource>
          <ObservationDefinition>
            <!-- LyophilizationWaterHomogeneity -->
            <id value="32e29d22-6fcb-546e-24fd-52a4a4004467"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="ObservationDefinition_32e29d22-6fcb-546e-24fd-52a4a4004467"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name="32e29d22-6fcb-546e-24fd-52a4a4004467"> </a><a name="hc32e29d22-6fcb-546e-24fd-52a4a4004467"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition &quot;32e29d22-6fcb-546e-24fd-52a4a4004467&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/32e29d22-6fcb-546e-24fd-52a4a4004467</code></p><p><b>title</b>: Water Content</p><p><b>status</b>: active</p><p><b>code</b>: Moisture (%) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#WWWH &quot;Water Content Homogeneity&quot;)</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Extension</b></td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td/><td>-1.5-1.5 % w/w</td></tr></table><blockquote><p><b>component</b></p><p><b>code</b>: Do statistically significant effects <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#SSE &quot;Statistically significant effects&quot;)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Lower one-sided 95% confidence limit of Max Difference <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#LCL)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Upper one-sided 95% confidence limit of Max Difference <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#UCL)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Was Homogeneity demonstrated? <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#Homogeneity &quot;Homogeneity demonstrated&quot;)</span></p></blockquote></div>
            </text>
            <!-- http://example-server.com/fhir/ObservationDefinition/32e29d22-6fcb-546e-24fd-52a4a4004467 -->
            <url
                 value="http://example-server.com/fhir/ObservationDefinition/32e29d22-6fcb-546e-24fd-52a4a4004467"/>
            <title value="Water Content"/>
            <status value="active"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="WWWH"/>
                <display value="Water Content Homogeneity"/>
              </coding>
              <text value="Moisture (%)"/>
            </code>
            <qualifiedValue>
              <extension
                         url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-display-pq">
                <valueString value="± 1.4 % (w/w)"/>
              </extension>
              <range>
                <low>
                  <value value="-1.5"/>
                  <unit value="% w/w"/>
                  <system value="http://unitsofmeasure.org"/>
                  <code value="%"/>
                </low>
                <high>
                  <value value="1.5"/>
                  <unit value="% w/w"/>
                  <system value="http://unitsofmeasure.org"/>
                  <code value="%"/>
                </high>
              </range>
            </qualifiedValue>
            <component>
              <code>
                <coding>
                  <system
                          value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                  <code value="SSE"/>
                  <display value="Statistically significant effects"/>
                </coding>
                <text value="Do statistically significant effects"/>
              </code>
            </component>
            <component>
              <code>
                <coding>
                  <system
                          value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                  <code value="LCL"/>
                  <display
                           value="Lower one-sided 95% confidence limit of Max Difference"/>
                </coding>
                <text
                      value="Lower one-sided 95% confidence limit of Max Difference"/>
              </code>
            </component>
            <component>
              <code>
                <coding>
                  <system
                          value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                  <code value="UCL"/>
                  <display
                           value="Upper one-sided 95% confidence limit of Max Difference"/>
                </coding>
                <text
                      value="Upper one-sided 95% confidence limit of Max Difference"/>
              </code>
            </component>
            <component>
              <code>
                <coding>
                  <system
                          value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                  <code value="Homogeneity"/>
                  <display value="Homogeneity demonstrated"/>
                </coding>
                <text value="Was Homogeneity demonstrated?"/>
              </code>
            </component>
          </ObservationDefinition>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:32e29d32-6fcb-546e-24fd-52a4a4004467"/>
        <resource>
          <ObservationDefinition>
            <!-- LyophilizationAssayHomogeneity -->
            <id value="32e29d32-6fcb-546e-24fd-52a4a4004467"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="ObservationDefinition_32e29d32-6fcb-546e-24fd-52a4a4004467"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name="32e29d32-6fcb-546e-24fd-52a4a4004467"> </a><a name="hc32e29d32-6fcb-546e-24fd-52a4a4004467"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition &quot;32e29d32-6fcb-546e-24fd-52a4a4004467&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/32e29d32-6fcb-546e-24fd-52a4a4004467</code></p><p><b>title</b>: Assay</p><p><b>status</b>: active</p><p><b>code</b>: Assay by HPLC (% Main Peak) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#ASSH &quot;Assay Content Homogeneity&quot;)</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Extension</b></td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td/><td>-2.3-2.3 %</td></tr></table><blockquote><p><b>component</b></p><p><b>code</b>: Do statistically significant effects <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#SSE &quot;Statistically significant effects&quot;)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Lower one-sided 95% confidence limit of Max Difference <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#LCL)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Upper one-sided 95% confidence limit of Max Difference <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#UCL)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Was Homogeneity demonstrated? <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#Homogeneity &quot;Homogeneity demonstrated&quot;)</span></p></blockquote></div>
            </text>
            <!-- http://example-server.com/fhir/ObservationDefinition/32e29d32-6fcb-546e-24fd-52a4a4004467 -->
            <url
                 value="http://example-server.com/fhir/ObservationDefinition/32e29d32-6fcb-546e-24fd-52a4a4004467"/>
            <title value="Assay"/>
            <status value="active"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="ASSH"/>
                <display value="Assay Content Homogeneity"/>
              </coding>
              <text value="Assay by HPLC (% Main Peak)"/>
            </code>
            <qualifiedValue>
              <extension
                         url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-display-pq">
                <valueString value="± 2.3%"/>
              </extension>
              <range>
                <low>
                  <value value="-2.3"/>
                  <unit value="%"/>
                  <system value="http://unitsofmeasure.org"/>
                  <code value="%"/>
                </low>
                <high>
                  <value value="2.3"/>
                  <unit value="%"/>
                  <system value="http://unitsofmeasure.org"/>
                  <code value="%"/>
                </high>
              </range>
            </qualifiedValue>
            <component>
              <code>
                <coding>
                  <system
                          value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                  <code value="SSE"/>
                  <display value="Statistically significant effects"/>
                </coding>
                <text value="Do statistically significant effects"/>
              </code>
            </component>
            <component>
              <code>
                <coding>
                  <system
                          value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                  <code value="LCL"/>
                  <display
                           value="Lower one-sided 95% confidence limit of Max Difference"/>
                </coding>
                <text
                      value="Lower one-sided 95% confidence limit of Max Difference"/>
              </code>
            </component>
            <component>
              <code>
                <coding>
                  <system
                          value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                  <code value="UCL"/>
                  <display
                           value="Upper one-sided 95% confidence limit of Max Difference"/>
                </coding>
                <text
                      value="Upper one-sided 95% confidence limit of Max Difference"/>
              </code>
            </component>
            <component>
              <code>
                <coding>
                  <system
                          value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                  <code value="Homogeneity"/>
                  <display value="Homogeneity demonstrated"/>
                </coding>
                <text value="Was Homogeneity demonstrated?"/>
              </code>
            </component>
          </ObservationDefinition>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:ef17cff1-6586-a5a4-9168-2602140548d7"/>
        <resource>
          <ObservationDefinition>
            <!-- UniformityUSP -->
            <id value="ef17cff1-6586-a5a4-9168-2602140548d7"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="ObservationDefinition_ef17cff1-6586-a5a4-9168-2602140548d7"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name="ef17cff1-6586-a5a4-9168-2602140548d7"> </a><a name="hcef17cff1-6586-a5a4-9168-2602140548d7"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition &quot;ef17cff1-6586-a5a4-9168-2602140548d7&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/ef17cff1-6586-a5a4-9168-2602140548d7</code></p><p><b>title</b>: Uniformity of Dosage Units, Weight Variation - Meets USP / Ph. Eur. requirements (% label claim)</p><p><b>status</b>: active</p><p><b>code</b>: Uniformity of Dosage Units, Weight Variation <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#Uniformity of Dosage Units, Weight Variation)</span></p><p><b>method</b>: Weight variation <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td>97-? %</td></tr></table></div>
            </text>
            <!-- http://example-server.com/fhir/ObservationDefinition/ef17cff1-6586-a5a4-9168-2602140548d7 -->
            <url
                 value="http://example-server.com/fhir/ObservationDefinition/ef17cff1-6586-a5a4-9168-2602140548d7"/>
            <title
                   value="Uniformity of Dosage Units, Weight Variation - Meets USP / Ph. Eur. requirements (% label claim)"/>
            <status value="active"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="Uniformity of Dosage Units, Weight Variation"/>
                <display value="Uniformity of Dosage Units, Weight Variation"/>
              </coding>
              <text value="Uniformity of Dosage Units, Weight Variation"/>
            </code>
            <method>
              <text value="Weight variation"/>
            </method>
            <qualifiedValue>
              <range>
                <low>
                  <value value="97"/>
                  <unit value="%"/>
                  <system value="http://unitsofmeasure.org"/>
                  <code value="%"/>
                </low>
              </range>
            </qualifiedValue>
          </ObservationDefinition>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:ef17cff1-6586-a5a4-9168-2602140548d8"/>
        <resource>
          <ObservationDefinition>
            <!-- UniformityAcceptance -->
            <id value="ef17cff1-6586-a5a4-9168-2602140548d8"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="ObservationDefinition_ef17cff1-6586-a5a4-9168-2602140548d8"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name="ef17cff1-6586-a5a4-9168-2602140548d8"> </a><a name="hcef17cff1-6586-a5a4-9168-2602140548d8"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition &quot;ef17cff1-6586-a5a4-9168-2602140548d8&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/ef17cff1-6586-a5a4-9168-2602140548d8</code></p><p><b>title</b>: Uniformity of Dosage Units, Weight Variation - Acceptance Value (AV)</p><p><b>status</b>: active</p><p><b>code</b>: Uniformity of Dosage Units, Weight Variation - Acceptance Value (AV) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#Uniformity of Dosage Units, Weight Variation - Acceptance Value (AV))</span></p><p><b>method</b>: Weight variation <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td>?-25</td></tr></table></div>
            </text>
            <!-- http://example-server.com/fhir/ObservationDefinition/ef17cff1-6586-a5a4-9168-2602140548d8 -->
            <url
                 value="http://example-server.com/fhir/ObservationDefinition/ef17cff1-6586-a5a4-9168-2602140548d8"/>
            <title
                   value="Uniformity of Dosage Units, Weight Variation - Acceptance Value (AV)"/>
            <status value="active"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code
                      value="Uniformity of Dosage Units, Weight Variation - Acceptance Value (AV)"/>
                <display
                         value="Uniformity of Dosage Units, Weight Variation - Acceptance Value (AV)"/>
              </coding>
              <text
                    value="Uniformity of Dosage Units, Weight Variation - Acceptance Value (AV)"/>
            </code>
            <method>
              <text value="Weight variation"/>
            </method>
            <qualifiedValue>
              <range>
                <!--  what are units of acceptance value?  -->
                <high>
                  <value value="25"/>
                </high>
              </range>
            </qualifiedValue>
          </ObservationDefinition>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:fc17b5d6-9fe1-91c2-2d06-47cb5b295e72"/>
        <resource>
          <ObservationDefinition>
            <!-- releasepH -->
            <id value="fc17b5d6-9fe1-91c2-2d06-47cb5b295e72"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="ObservationDefinition_fc17b5d6-9fe1-91c2-2d06-47cb5b295e72"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name="fc17b5d6-9fe1-91c2-2d06-47cb5b295e72"> </a><a name="hcfc17b5d6-9fe1-91c2-2d06-47cb5b295e72"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition &quot;fc17b5d6-9fe1-91c2-2d06-47cb5b295e72&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/fc17b5d6-9fe1-91c2-2d06-47cb5b295e72</code></p><p><b>title</b>: pH (reconstituted)</p><p><b>status</b>: active</p><p><b>code</b>: pH (reconstituted) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#pH (reconstituted))</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td>6.95-7.05 pH</td></tr></table></div>
            </text>
            <!-- http://example-server.com/fhir/ObservationDefinition/fc17b5d6-9fe1-91c2-2d06-47cb5b295e72 -->
            <url
                 value="http://example-server.com/fhir/ObservationDefinition/fc17b5d6-9fe1-91c2-2d06-47cb5b295e72"/>
            <title value="pH (reconstituted)"/>
            <status value="active"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="pH (reconstituted)"/>
                <display value="pH (reconstituted)"/>
              </coding>
              <text value="pH (reconstituted)"/>
            </code>
            <qualifiedValue>
              <range>
                <low>
                  <value value="6.95"/>
                  <unit value="pH"/>
                  <system value="http://unitsofmeasure.org"/>
                  <code value="pH"/>
                </low>
                <high>
                  <value value="7.05"/>
                  <unit value="pH"/>
                  <system value="http://unitsofmeasure.org"/>
                  <code value="pH"/>
                </high>
              </range>
            </qualifiedValue>
          </ObservationDefinition>
        </resource>
      </entry>
      <!--  filling steps  -->
      <entry>
        <fullUrl value="urn:uuid:22515a3c-5034-448a-9c19-938ce1958424"/>
        <resource>
          <ObservationDefinition>
            <!-- conclusion -->
            <id value="22515a3c-5034-448a-9c19-938ce1958424"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="ObservationDefinition_22515a3c-5034-448a-9c19-938ce1958424"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name="22515a3c-5034-448a-9c19-938ce1958424"> </a><a name="hc22515a3c-5034-448a-9c19-938ce1958424"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition &quot;22515a3c-5034-448a-9c19-938ce1958424&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/22515a3c-5034-448a-9c19-938ce1958424</code></p><p><b>title</b>: Conclusion</p><p><b>status</b>: active</p><p><b>code</b>: Conclusion <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#CONC)</span></p></div>
            </text>
            <!-- http://example-server.com/fhir/ObservationDefinition/22515a3c-5034-448a-9c19-938ce1958424 -->
            <url
                 value="http://example-server.com/fhir/ObservationDefinition/22515a3c-5034-448a-9c19-938ce1958424"/>
            <title value="Conclusion"/>
            <status value="active"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="CONC"/>
                <display value="Conclusion"/>
              </coding>
              <text value="Conclusion"/>
            </code>
          </ObservationDefinition>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:64505a3c-5034-448a-9c19-938ce1958424"/>
        <resource>
          <ObservationDefinition>
            <!-- TAMC -->
            <id value="64505a3c-5034-448a-9c19-938ce1958424"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="ObservationDefinition_64505a3c-5034-448a-9c19-938ce1958424"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name="64505a3c-5034-448a-9c19-938ce1958424"> </a><a name="hc64505a3c-5034-448a-9c19-938ce1958424"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition &quot;64505a3c-5034-448a-9c19-938ce1958424&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/64505a3c-5034-448a-9c19-938ce1958424</code></p><p><b>title</b>: TAMC [a]</p><p><b>status</b>: active</p><p><b>code</b>: TAMC <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#TAMC)</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td>?-10</td></tr></table></div>
            </text>
            <!-- http://example-server.com/fhir/ObservationDefinition/64505a3c-5034-448a-9c19-938ce1958424 -->
            <url
                 value="http://example-server.com/fhir/ObservationDefinition/64505a3c-5034-448a-9c19-938ce1958424"/>
            <title value="TAMC [a]"/>
            <status value="active"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="TAMC"/>
                <display value="TAMC"/>
              </coding>
              <text value="TAMC"/>
            </code>
            <qualifiedValue>
              <range>
                <!--  todo UCUM  -->
                <high>
                  <value value="10"/>
                  <unit value="CFU/100ml"/>
                </high>
              </range>
            </qualifiedValue>
          </ObservationDefinition>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:64515a3c-5034-448a-9c19-938ce1958424"/>
        <resource>
          <ObservationDefinition>
            <!-- TYMC -->
            <id value="64515a3c-5034-448a-9c19-938ce1958424"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="ObservationDefinition_64515a3c-5034-448a-9c19-938ce1958424"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name="64515a3c-5034-448a-9c19-938ce1958424"> </a><a name="hc64515a3c-5034-448a-9c19-938ce1958424"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition &quot;64515a3c-5034-448a-9c19-938ce1958424&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/64515a3c-5034-448a-9c19-938ce1958424</code></p><p><b>title</b>: TYMC [a]</p><p><b>status</b>: active</p><p><b>code</b>: TAMC <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#TAMC)</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td>?-10</td></tr></table></div>
            </text>
            <!-- http://example-server.com/fhir/ObservationDefinition/64515a3c-5034-448a-9c19-938ce1958424 -->
            <url
                 value="http://example-server.com/fhir/ObservationDefinition/64515a3c-5034-448a-9c19-938ce1958424"/>
            <title value="TYMC [a]"/>
            <status value="active"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="TAMC"/>
                <display value="TAMC"/>
              </coding>
              <text value="TAMC"/>
            </code>
            <qualifiedValue>
              <range>
                <!--  todo UCUM  -->
                <high>
                  <value value="10"/>
                  <unit value="CFU/100ml"/>
                </high>
              </range>
            </qualifiedValue>
          </ObservationDefinition>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:64515a3c-5134-448a-9c19-938ce1958424"/>
        <resource>
          <ObservationDefinition>
            <!-- FillWeightAverage -->
            <id value="64515a3c-5134-448a-9c19-938ce1958424"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="ObservationDefinition_64515a3c-5134-448a-9c19-938ce1958424"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name="64515a3c-5134-448a-9c19-938ce1958424"> </a><a name="hc64515a3c-5134-448a-9c19-938ce1958424"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition &quot;64515a3c-5134-448a-9c19-938ce1958424&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/64515a3c-5134-448a-9c19-938ce1958424</code></p><p><b>title</b>: Fill Weight Average</p><p><b>status</b>: active</p><p><b>code</b>: Fill Weight Average <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#Fill Weight Average)</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Extension</b></td></tr><tr><td style="display: none">*</td><td/></tr></table></div>
            </text>
            <!-- http://example-server.com/fhir/ObservationDefinition/64515a3c-5134-448a-9c19-938ce1958424 -->
            <url
                 value="http://example-server.com/fhir/ObservationDefinition/64515a3c-5134-448a-9c19-938ce1958424"/>
            <title value="Fill Weight Average"/>
            <status value="active"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="Fill Weight Average"/>
                <display value="Fill Weight Average"/>
              </coding>
            </code>
            <qualifiedValue>
              <!--  todo probably want to just not have this, detect that, and show as N/A  -->
              <extension
                         url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-text-pq">
                <valueString value="N/A"/>
              </extension>
            </qualifiedValue>
          </ObservationDefinition>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:64525a3c-5134-448a-9c19-938ce1958424"/>
        <resource>
          <ObservationDefinition>
            <!-- FillWeightTarget -->
            <id value="64525a3c-5134-448a-9c19-938ce1958424"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="ObservationDefinition_64525a3c-5134-448a-9c19-938ce1958424"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name="64525a3c-5134-448a-9c19-938ce1958424"> </a><a name="hc64525a3c-5134-448a-9c19-938ce1958424"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition &quot;64525a3c-5134-448a-9c19-938ce1958424&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/64525a3c-5134-448a-9c19-938ce1958424</code></p><p><b>title</b>: Fill Weight Target</p><p><b>status</b>: active</p><p><b>code</b>: Fill Weight Target (g) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#Fill Weight Target (g))</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Extension</b></td></tr><tr><td style="display: none">*</td><td/></tr></table></div>
            </text>
            <!-- http://example-server.com/fhir/ObservationDefinition/64525a3c-5134-448a-9c19-938ce1958424 -->
            <url
                 value="http://example-server.com/fhir/ObservationDefinition/64525a3c-5134-448a-9c19-938ce1958424"/>
            <title value="Fill Weight Target"/>
            <status value="active"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="Fill Weight Target (g)"/>
                <display value="Fill Weight Target (g)"/>
              </coding>
            </code>
            <qualifiedValue>
              <!--  todo probably want to just not have this, detect that, and show as N/A  -->
              <extension
                         url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-text-pq">
                <valueString value="N/A"/>
              </extension>
            </qualifiedValue>
          </ObservationDefinition>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:64515a3c-5134-448a-9c29-938ce1958424"/>
        <resource>
          <ObservationDefinition>
            <!-- FillWeightAverageFromTarget -->
            <id value="64515a3c-5134-448a-9c29-938ce1958424"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="ObservationDefinition_64515a3c-5134-448a-9c29-938ce1958424"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name="64515a3c-5134-448a-9c29-938ce1958424"> </a><a name="hc64515a3c-5134-448a-9c29-938ce1958424"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition &quot;64515a3c-5134-448a-9c29-938ce1958424&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/64515a3c-5134-448a-9c29-938ce1958424</code></p><p><b>title</b>: Actual Avg. Weight from Target</p><p><b>status</b>: active</p><p><b>code</b>: Actual Avg. Weight from Target <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#Actual Avg. Weight from Target)</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Extension</b></td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td/><td>2-2 %</td></tr></table></div>
            </text>
            <!-- http://example-server.com/fhir/ObservationDefinition/64515a3c-5134-448a-9c29-938ce1958424 -->
            <url
                 value="http://example-server.com/fhir/ObservationDefinition/64515a3c-5134-448a-9c29-938ce1958424"/>
            <title value="Actual Avg. Weight from Target"/>
            <status value="active"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="Actual Avg. Weight from Target"/>
                <display value="Actual Avg. Weight from Target"/>
              </coding>
            </code>
            <qualifiedValue>
              <extension
                         url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-display-pq">
                <valueString value="± 2% target (%)"/>
              </extension>
              <range>
                <low>
                  <value value="2"/>
                  <unit value="%"/>
                  <system value="http://unitsofmeasure.org"/>
                  <code value="%"/>
                </low>
                <high>
                  <value value="2"/>
                  <unit value="%"/>
                  <system value="http://unitsofmeasure.org"/>
                  <code value="%"/>
                </high>
              </range>
            </qualifiedValue>
          </ObservationDefinition>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:64515a3c-5234-448a-9c29-938ce1958424"/>
        <resource>
          <ObservationDefinition>
            <!-- HoldTimeFiltrationToFilling -->
            <id value="64515a3c-5234-448a-9c29-938ce1958424"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="ObservationDefinition_64515a3c-5234-448a-9c29-938ce1958424"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name="64515a3c-5234-448a-9c29-938ce1958424"> </a><a name="hc64515a3c-5234-448a-9c29-938ce1958424"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition &quot;64515a3c-5234-448a-9c29-938ce1958424&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/64515a3c-5234-448a-9c29-938ce1958424</code></p><p><b>title</b>: Hold Time (filtration To filling)</p><p><b>status</b>: active</p><p><b>code</b>: Hold Time (filtration To filling) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#Hold Time (filtration To filling))</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td>?-2.5</td></tr></table></div>
            </text>
            <!-- http://example-server.com/fhir/ObservationDefinition/64515a3c-5234-448a-9c29-938ce1958424 -->
            <url
                 value="http://example-server.com/fhir/ObservationDefinition/64515a3c-5234-448a-9c29-938ce1958424"/>
            <title value="Hold Time (filtration To filling)"/>
            <status value="active"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="Hold Time (filtration To filling)"/>
                <display value="Hold Time (filtration To filling)"/>
              </coding>
            </code>
            <qualifiedValue>
              <range>
                <high>
                  <value value="2.5"/>
                  <unit value="hours"/>
                  <system value="http://unitsofmeasure.org"/>
                  <code value="h"/>
                </high>
              </range>
            </qualifiedValue>
          </ObservationDefinition>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:64515a3c-5334-448a-9c29-938ce1958424"/>
        <resource>
          <ObservationDefinition>
            <!-- HoldTimeFilling -->
            <id value="64515a3c-5334-448a-9c29-938ce1958424"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="ObservationDefinition_64515a3c-5334-448a-9c29-938ce1958424"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name="64515a3c-5334-448a-9c29-938ce1958424"> </a><a name="hc64515a3c-5334-448a-9c29-938ce1958424"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition &quot;64515a3c-5334-448a-9c29-938ce1958424&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/64515a3c-5334-448a-9c29-938ce1958424</code></p><p><b>title</b>: Hold Time (start filling to end filling)</p><p><b>status</b>: active</p><p><b>code</b>: Hold Time (start filling to end filling) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#Hold Time (start filling to end filling))</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td>?-1.25</td></tr></table></div>
            </text>
            <!-- http://example-server.com/fhir/ObservationDefinition/64515a3c-5334-448a-9c29-938ce1958424 -->
            <url
                 value="http://example-server.com/fhir/ObservationDefinition/64515a3c-5334-448a-9c29-938ce1958424"/>
            <title value="Hold Time (start filling to end filling)"/>
            <status value="active"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="Hold Time (start filling to end filling)"/>
                <display value="Hold Time (start filling to end filling)"/>
              </coding>
            </code>
            <qualifiedValue>
              <range>
                <high>
                  <value value="1.25"/>
                  <unit value="hours"/>
                  <system value="http://unitsofmeasure.org"/>
                  <code value="h"/>
                </high>
              </range>
            </qualifiedValue>
          </ObservationDefinition>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:64535a3c-5334-448a-9c29-938ce1958424"/>
        <resource>
          <ObservationDefinition>
            <!-- FilterIntegrity -->
            <id value="64535a3c-5334-448a-9c29-938ce1958424"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="ObservationDefinition_64535a3c-5334-448a-9c29-938ce1958424"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name="64535a3c-5334-448a-9c29-938ce1958424"> </a><a name="hc64535a3c-5334-448a-9c29-938ce1958424"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition &quot;64535a3c-5334-448a-9c29-938ce1958424&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/64535a3c-5334-448a-9c29-938ce1958424</code></p><p><b>title</b>: Filter Integrity Test</p><p><b>status</b>: active</p><p><b>code</b>: Filter Integrity Test <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#Filter Integrity Test)</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td>3.5-? psi</td></tr></table></div>
            </text>
            <!-- http://example-server.com/fhir/ObservationDefinition/64535a3c-5334-448a-9c29-938ce1958424 -->
            <url
                 value="http://example-server.com/fhir/ObservationDefinition/64535a3c-5334-448a-9c29-938ce1958424"/>
            <title value="Filter Integrity Test"/>
            <status value="active"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="Filter Integrity Test"/>
                <display value="Filter Integrity Test"/>
              </coding>
            </code>
            <qualifiedValue>
              <range>
                <!--  out of scope of ucum apparently  -->
                <low>
                  <value value="3.5"/>
                  <unit value="psi"/>
                  <system value="http://unitsofmeasure.org"/>
                  <code value="[psi]"/>
                </low>
              </range>
            </qualifiedValue>
          </ObservationDefinition>
        </resource>
      </entry>
      <!--  Lyophilization step  -->
      <entry>
        <fullUrl value="urn:uuid:22525a3c-5034-448a-9c19-938ce1958424"/>
        <resource>
          <ObservationDefinition>
            <!-- LyophilizationConclusion -->
            <id value="22525a3c-5034-448a-9c19-938ce1958424"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="ObservationDefinition_22525a3c-5034-448a-9c19-938ce1958424"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name="22525a3c-5034-448a-9c19-938ce1958424"> </a><a name="hc22525a3c-5034-448a-9c19-938ce1958424"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition &quot;22525a3c-5034-448a-9c19-938ce1958424&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/22525a3c-5034-448a-9c19-938ce1958424</code></p><p><b>title</b>: Conclusion</p><p><b>status</b>: active</p><p><b>code</b>: Conclusion <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#CONC)</span></p></div>
            </text>
            <!-- http://example-server.com/fhir/ObservationDefinition/22525a3c-5034-448a-9c19-938ce1958424 -->
            <url
                 value="http://example-server.com/fhir/ObservationDefinition/22525a3c-5034-448a-9c19-938ce1958424"/>
            <title value="Conclusion"/>
            <status value="active"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="CONC"/>
                <display value="Conclusion"/>
              </coding>
              <text value="Conclusion"/>
            </code>
          </ObservationDefinition>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:64535a3c-5334-448a-9c29-938ce2958424"/>
        <!-- qualifiedValue>

    				</qualifiedValue -->
        <resource>
          <ObservationDefinition>
            <!-- LyophilizerNumber -->
            <id value="64535a3c-5334-448a-9c29-938ce2958424"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="ObservationDefinition_64535a3c-5334-448a-9c29-938ce2958424"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name="64535a3c-5334-448a-9c29-938ce2958424"> </a><a name="hc64535a3c-5334-448a-9c29-938ce2958424"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition &quot;64535a3c-5334-448a-9c29-938ce2958424&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/64535a3c-5334-448a-9c29-938ce2958424</code></p><p><b>title</b>: Lyophilizer Number</p><p><b>status</b>: active</p><p><b>code</b>: Lyophilizer Number <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#Lyophilizer Number)</span></p></div>
            </text>
            <!-- http://example-server.com/fhir/ObservationDefinition/64535a3c-5334-448a-9c29-938ce2958424 -->
            <url
                 value="http://example-server.com/fhir/ObservationDefinition/64535a3c-5334-448a-9c29-938ce2958424"/>
            <title value="Lyophilizer Number"/>
            <status value="active"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="Lyophilizer Number"/>
                <display value="Lyophilizer Number"/>
              </coding>
            </code>
          </ObservationDefinition>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:22e7e672-40a6-4036-3c1f-b8ba6a7d045e"/>
        <resource>
          <ObservationDefinition>
            <!-- LyophilizationAssay -->
            <id value="22e7e672-40a6-4036-3c1f-b8ba6a7d045e"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="ObservationDefinition_22e7e672-40a6-4036-3c1f-b8ba6a7d045e"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name="22e7e672-40a6-4036-3c1f-b8ba6a7d045e"> </a><a name="hc22e7e672-40a6-4036-3c1f-b8ba6a7d045e"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition &quot;22e7e672-40a6-4036-3c1f-b8ba6a7d045e&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/22e7e672-40a6-4036-3c1f-b8ba6a7d045e</code></p><p><b>title</b>: Assay</p><p><b>status</b>: active</p><p><b>code</b>: Assay <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#ASSAY)</span></p><p><b>method</b>: Assay by UHPLC <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Extension</b></td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td/><td>95-105 %</td></tr></table><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td></tr><tr><td style="display: none">*</td><td>Number of Locations <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#LOC)</span></td></tr></table></div>
            </text>
            <!-- http://example-server.com/fhir/ObservationDefinition/22e7e672-40a6-4036-3c1f-b8ba6a7d045e -->
            <url
                 value="http://example-server.com/fhir/ObservationDefinition/22e7e672-40a6-4036-3c1f-b8ba6a7d045e"/>
            <title value="Assay"/>
            <status value="active"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="ASSAY"/>
                <display value="Assay"/>
              </coding>
              <text value="Assay"/>
            </code>
            <method>
              <text value="Assay by UHPLC"/>
            </method>
            <qualifiedValue>
              <extension
                         url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-display-pq">
                <valueString value="95% to 105% of label claim"/>
              </extension>
              <range>
                <low>
                  <value value="95"/>
                  <unit value="%"/>
                  <system value="http://unitsofmeasure.org"/>
                  <code value="%"/>
                </low>
                <high>
                  <value value="105"/>
                  <unit value="%"/>
                  <system value="http://unitsofmeasure.org"/>
                  <code value="%"/>
                </high>
              </range>
            </qualifiedValue>
            <component>
              <!--  are expected to have a component that says number of locations  -->
              <code>
                <coding>
                  <system
                          value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                  <code value="LOC"/>
                  <display value="Number of Locations"/>
                </coding>
              </code>
            </component>
          </ObservationDefinition>
        </resource>
      </entry>
      <!--  Section 8 - Batch or Lot Information (batch 1 of 3)  -->
      <entry>
        <fullUrl value="urn:uuid:339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"/>
        <resource>
          <Medication>
            <!-- medication-batch-information-drug-pq-ex1 -->
            <id value="339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"/>
            <meta>
              <profile
                       value="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Medication-batch-information-drug-pq"/>
            </meta>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Medication_339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"> </a><p><b>Generated Narrative: Medication</b><a name="339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"> </a><a name="hc339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Medication &quot;339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51&quot; </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-Medication-batch-information-drug-pq.html">Medication - Batch Information Drug PQ</a></p></div><p><b>code</b>:  <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><h3>Batches</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Extension</b></td><td><b>LotNumber</b></td></tr><tr><td style="display: none">*</td><td>, , , , , , , , , </td><td>33445</td></tr></table></div>
            </text>
            <code>
              <extension
                         url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-medication-definition-pq">
                <valueReference>
                  <!--  todo consider change this be the MID?  -->
                  <!-- MedicinalProductDefinition/medicinalproductdefinition-drug-product-pq-ex1 -->
                  <reference
                             value="MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"/>
                </valueReference>
              </extension>
            </code>
            <batch>
              <extension
                         url="http://hl7.org/fhir/StructureDefinition/medication-manufacturingBatch">
                <extension url="manufacturingDate">
                  <valueDateTime value="2020-06"/>
                </extension>
                <extension url="batchQuantity">
                  <valueQuantity>
                    <value value="100100"/>
                    <unit value="tablets"/>
                  </valueQuantity>
                </extension>
                <extension url="batchUtilization">
                  <valueCodeableConcept>
                    <coding>
                      <system
                              value="http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"/>
                      <code value="C133990"/>
                      <display value="Commercial"/>
                    </coding>
                    <text value="Production"/>
                  </valueCodeableConcept>
                </extension>
                <extension url="assignedManufacturer">
                  <valueReference>
                    <!-- Organization/organization-drug-pq-ex1 -->
                    <reference
                               value="Organization/49d2f0c0-4b28-9271-8aaf-2996a8b9739c"/>
                  </valueReference>
                </extension>
                <extension url="container">
                  <extension url="closureSystemDescription">
                    <valueString value="100 cc HDPE Bottle 2 g desiccant"/>
                  </extension>
                </extension>
              </extension>
              <!--  local extensions  -->
              <extension
                         url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-release-date-pq">
                <valueDateTime value="2019-09-08"/>
              </extension>
              <extension
                         url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-designation-pq">
                <valueCodeableConcept>
                  <coding>
                    <system
                            value="http://terminology.hl7.org/CodeSystem/batch-designation"/>
                    <code value="maximum"/>
                    <display value="Maximum"/>
                  </coding>
                  <text value="Maximum"/>
                </valueCodeableConcept>
              </extension>
              <extension
                         url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-number-of-vials-pq">
                <valuePositiveInt value="3"/>
              </extension>
              <extension
                         url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-substance-batch-pq">
                <valueReference>
                  <!-- Substance/substance-drug-pq-ex1 -->
                  <reference
                             value="Substance/fc078762-81c5-5656-9744-13c7ad1e595b"/>
                </valueReference>
              </extension>
              <extension
                         url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-packaging-date-pq">
                <valueDateTime value="2020-08"/>
              </extension>
              <extension
                         url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-packaging-site-pq">
                <valueReference>
                  <!-- Organization/organization-drug-pq-ex1 -->
                  <reference
                             value="Organization/49d2f0c0-4b28-9271-8aaf-2996a8b9739c"/>
                </valueReference>
              </extension>
              <extension
                         url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-pq">
                <valueQuantity>
                  <value value="4.81"/>
                  <unit value="kg"/>
                </valueQuantity>
              </extension>
              <extension
                         url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-unfiltered-pq">
                <valueQuantity>
                  <value value="4.91"/>
                  <unit value="kg"/>
                </valueQuantity>
              </extension>
              <extension
                         url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-target-fill-weight-pq">
                <valueQuantity>
                  <value value="30"/>
                  <unit value="g"/>
                </valueQuantity>
              </extension>
              <lotNumber value="33445"/>
            </batch>
          </Medication>
        </resource>
      </entry>
      <!--  Section 8 - Batch or Lot Information (another batch 2 of 3)  -->
      <entry>
        <fullUrl value="urn:uuid:a9dfda53-734b-045f-7ae4-94a6281d53bc"/>
        <resource>
          <Medication>
            <!-- medication-actual-batch-2 -->
            <id value="a9dfda53-734b-045f-7ae4-94a6281d53bc"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Medication_a9dfda53-734b-045f-7ae4-94a6281d53bc"> </a><p><b>Generated Narrative: Medication</b><a name="a9dfda53-734b-045f-7ae4-94a6281d53bc"> </a><a name="hca9dfda53-734b-045f-7ae4-94a6281d53bc"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Medication &quot;a9dfda53-734b-045f-7ae4-94a6281d53bc&quot; </p></div><p><b>code</b>:  <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><h3>Batches</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Extension</b></td><td><b>LotNumber</b></td></tr><tr><td style="display: none">*</td><td>, , , , , , , , , </td><td>33446</td></tr></table></div>
            </text>
            <code>
              <extension
                         url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-medication-definition-pq">
                <valueReference>
                  <!-- MedicinalProductDefinition/medicinalproductdefinition-drug-product-pq-ex1 -->
                  <reference
                             value="MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"/>
                </valueReference>
              </extension>
            </code>
            <batch>
              <extension
                         url="http://hl7.org/fhir/StructureDefinition/medication-manufacturingBatch">
                <extension url="manufacturingDate">
                  <valueDateTime value="2020-06"/>
                </extension>
                <extension url="batchQuantity">
                  <valueQuantity>
                    <value value="100050"/>
                    <unit value="tablets"/>
                  </valueQuantity>
                </extension>
                <extension url="batchUtilization">
                  <valueCodeableConcept>
                    <coding>
                      <system
                              value="http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"/>
                      <code value="C185328"/>
                      <display value="Stability Study"/>
                    </coding>
                    <text value="PPQ / Stability"/>
                  </valueCodeableConcept>
                </extension>
                <extension url="assignedManufacturer">
                  <valueReference>
                    <!-- Organization/manufacturer -->
                    <reference
                               value="Organization/0102bca4-46c1-a6bf-1025-cd403fee710a"/>
                  </valueReference>
                </extension>
                <extension url="container">
                  <extension url="closureSystemDescription">
                    <valueString value="100 cc HDPE Bottle 2 g desiccant"/>
                  </extension>
                </extension>
              </extension>
              <!--  local extensions  -->
              <extension
                         url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-release-date-pq">
                <valueDateTime value="2019-09-08"/>
              </extension>
              <extension
                         url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-designation-pq">
                <valueCodeableConcept>
                  <coding>
                    <system
                            value="http://terminology.hl7.org/CodeSystem/batch-designation"/>
                    <code value="maximum"/>
                    <display value="Maximum"/>
                  </coding>
                  <text value="Maximum"/>
                </valueCodeableConcept>
              </extension>
              <extension
                         url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-number-of-vials-pq">
                <valuePositiveInt value="4"/>
              </extension>
              <extension
                         url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-substance-batch-pq">
                <valueReference>
                  <!-- Substance/actual-batch-substance-2 -->
                  <reference
                             value="Substance/cb31d747-2338-88d5-342c-8e9c097e4dad"/>
                </valueReference>
              </extension>
              <extension
                         url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-packaging-date-pq">
                <valueDateTime value="2020-08"/>
              </extension>
              <extension
                         url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-packaging-site-pq">
                <valueReference>
                  <!-- Organization/packaging -->
                  <reference
                             value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b07"/>
                </valueReference>
              </extension>
              <extension
                         url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-pq">
                <valueQuantity>
                  <value value="4.82"/>
                  <unit value="kg"/>
                </valueQuantity>
              </extension>
              <extension
                         url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-unfiltered-pq">
                <valueQuantity>
                  <value value="4.92"/>
                  <unit value="kg"/>
                </valueQuantity>
              </extension>
              <extension
                         url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-target-fill-weight-pq">
                <valueQuantity>
                  <value value="30"/>
                  <unit value="g"/>
                </valueQuantity>
              </extension>
              <lotNumber value="33446"/>
            </batch>
          </Medication>
        </resource>
      </entry>
      <!--  Section 8 - Batch or Lot Information (another batch 3 of 3)  -->
      <entry>
        <fullUrl value="urn:uuid:c6f5fadd-62e6-3a01-93d9-b3b182f67d06"/>
        <resource>
          <Medication>
            <!-- medication-actual-batch-3 -->
            <id value="c6f5fadd-62e6-3a01-93d9-b3b182f67d06"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Medication_c6f5fadd-62e6-3a01-93d9-b3b182f67d06"> </a><p><b>Generated Narrative: Medication</b><a name="c6f5fadd-62e6-3a01-93d9-b3b182f67d06"> </a><a name="hcc6f5fadd-62e6-3a01-93d9-b3b182f67d06"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Medication &quot;c6f5fadd-62e6-3a01-93d9-b3b182f67d06&quot; </p></div><p><b>code</b>:  <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><h3>Batches</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Extension</b></td><td><b>LotNumber</b></td></tr><tr><td style="display: none">*</td><td>, , , , , , , , , </td><td>33447</td></tr></table></div>
            </text>
            <code>
              <extension
                         url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-medication-definition-pq">
                <valueReference>
                  <!-- MedicinalProductDefinition/medicinalproductdefinition-drug-product-pq-ex1 -->
                  <reference
                             value="MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"/>
                </valueReference>
              </extension>
            </code>
            <batch>
              <extension
                         url="http://hl7.org/fhir/StructureDefinition/medication-manufacturingBatch">
                <extension url="manufacturingDate">
                  <valueDateTime value="2020-06"/>
                </extension>
                <extension url="batchQuantity">
                  <valueQuantity>
                    <value value="100125"/>
                    <unit value="tablets"/>
                  </valueQuantity>
                </extension>
                <extension url="batchUtilization">
                  <valueCodeableConcept>
                    <coding>
                      <system
                              value="http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"/>
                      <code value="C185328"/>
                      <display value="Stability Study"/>
                    </coding>
                    <text value="PPQ / Stability"/>
                  </valueCodeableConcept>
                </extension>
                <extension url="assignedManufacturer">
                  <valueReference>
                    <!-- Organization/manufacturer -->
                    <reference
                               value="Organization/0102bca4-46c1-a6bf-1025-cd403fee710a"/>
                  </valueReference>
                </extension>
                <extension url="container">
                  <extension url="closureSystemDescription">
                    <valueString value="100 cc HDPE Bottle 2 g desiccant"/>
                  </extension>
                </extension>
              </extension>
              <!--  local exensions  -->
              <extension
                         url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-release-date-pq">
                <valueDateTime value="2019-09-08"/>
              </extension>
              <extension
                         url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-designation-pq">
                <valueCodeableConcept>
                  <coding>
                    <system
                            value="http://terminology.hl7.org/CodeSystem/batch-designation"/>
                    <code value="maximum"/>
                    <display value="Maximum"/>
                  </coding>
                  <text value="Maximum"/>
                </valueCodeableConcept>
              </extension>
              <extension
                         url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-packaging-date-pq">
                <valueDateTime value="2020-08"/>
              </extension>
              <extension
                         url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-number-of-vials-pq">
                <valuePositiveInt value="3"/>
              </extension>
              <extension
                         url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-substance-batch-pq">
                <valueReference>
                  <!-- Substance/actual-batch-substance-3 -->
                  <reference
                             value="Substance/1551f97b-6f6d-825e-1fb3-44b0b090808c"/>
                </valueReference>
              </extension>
              <extension
                         url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-packaging-site-pq">
                <valueReference>
                  <!-- Organization/packaging -->
                  <reference
                             value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b07"/>
                </valueReference>
              </extension>
              <extension
                         url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-pq">
                <valueQuantity>
                  <value value="4.83"/>
                  <unit value="kg"/>
                </valueQuantity>
              </extension>
              <extension
                         url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-unfiltered-pq">
                <valueQuantity>
                  <value value="4.93"/>
                  <unit value="kg"/>
                </valueQuantity>
              </extension>
              <extension
                         url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-target-fill-weight-pq">
                <valueQuantity>
                  <value value="30"/>
                  <unit value="g"/>
                </valueQuantity>
              </extension>
              <lotNumber value="33447"/>
            </batch>
          </Medication>
        </resource>
      </entry>
      <!--  Section 4.1 - Manufacturer  -->
      <entry>
        <fullUrl value="urn:uuid:0102bca4-46c1-a6bf-1025-cd403fee710a"/>
        <resource>
          <Organization>
            <!-- manufacturer -->
            <id value="0102bca4-46c1-a6bf-1025-cd403fee710a"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Organization_0102bca4-46c1-a6bf-1025-cd403fee710a"> </a><p><b>Generated Narrative: Organization</b><a name="0102bca4-46c1-a6bf-1025-cd403fee710a"> </a><a name="hc0102bca4-46c1-a6bf-1025-cd403fee710a"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Organization &quot;0102bca4-46c1-a6bf-1025-cd403fee710a&quot; </p></div><p><b>identifier</b>: <code>urn:oid:2.16.840.1.113883.4.82</code>/3010027650</p><p><b>active</b>: true</p><p><b>type</b>: Drug Product Manufacture <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-pharmaceutical-organization-type.html">Pharmaceutical Organization Type Codes</a>#drug-product-manufacture)</span></p><p><b>name</b>: AAA Pharmaceutical, Inc.</p><h3>Contacts</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Address</b></td></tr><tr><td style="display: none">*</td><td>681 Main Street Lumberton New Jersey 08048 USA </td></tr></table></div>
            </text>
            <identifier>
              <!--  FDA establishment identifier  -->
              <system value="urn:oid:2.16.840.1.113883.4.82"/>
              <value value="3010027650"/>
            </identifier>
            <active value="true"/>
            <type>
              <coding>
                <system
                        value="http://terminology.hl7.org/CodeSystem/pharmaceutical-organization-type"/>
                <code value="drug-product-manufacture"/>
                <display value="Drug Product Manufacture"/>
              </coding>
            </type>
            <name value="AAA Pharmaceutical, Inc."/>
            <contact>
              <address>
                <line value="681 Main Street"/>
                <city value="Lumberton"/>
                <state value="New Jersey"/>
                <postalCode value="08048"/>
                <country value="USA"/>
              </address>
            </contact>
          </Organization>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:378fbe5f-5926-3a5c-4c64-5428df877b07"/>
        <resource>
          <Organization>
            <!-- packaging -->
            <id value="378fbe5f-5926-3a5c-4c64-5428df877b07"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Organization_378fbe5f-5926-3a5c-4c64-5428df877b07"> </a><p><b>Generated Narrative: Organization</b><a name="378fbe5f-5926-3a5c-4c64-5428df877b07"> </a><a name="hc378fbe5f-5926-3a5c-4c64-5428df877b07"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Organization &quot;378fbe5f-5926-3a5c-4c64-5428df877b07&quot; </p></div><p><b>identifier</b>: <code>urn:oid:2.16.840.1.113883.4.82</code>/3008816891</p><p><b>active</b>: true</p><p><b>type</b>: Packaging <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-pharmaceutical-organization-type.html">Pharmaceutical Organization Type Codes</a>#packaging)</span></p><p><b>name</b>: MySite</p></div>
            </text>
            <identifier>
              <system value="urn:oid:2.16.840.1.113883.4.82"/>
              <value value="3008816891"/>
            </identifier>
            <active value="true"/>
            <type>
              <coding>
                <system
                        value="http://terminology.hl7.org/CodeSystem/pharmaceutical-organization-type"/>
                <code value="packaging"/>
                <display value="Packaging"/>
              </coding>
            </type>
            <name value="MySite"/>
          </Organization>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:378fbe5f-5926-3a5c-4c64-5428df877b08"/>
        <resource>
          <Organization>
            <!-- testing lab -->
            <!-- 378fbe5f-5926-3a5c-4c64-5428df877b08 -->
            <id value="378fbe5f-5926-3a5c-4c64-5428df877b08"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Organization_378fbe5f-5926-3a5c-4c64-5428df877b08"> </a><p><b>Generated Narrative: Organization</b><a name="378fbe5f-5926-3a5c-4c64-5428df877b08"> </a><a name="hc378fbe5f-5926-3a5c-4c64-5428df877b08"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Organization &quot;378fbe5f-5926-3a5c-4c64-5428df877b08&quot; </p></div><p><b>identifier</b>: <code>urn:oid:2.16.840.1.113883.4.82</code>/3007270600</p><p><b>active</b>: true</p><p><b>type</b>: Analytical Testing - Release <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-pharmaceutical-organization-type.html">Pharmaceutical Organization Type Codes</a>#analytical-testing-release)</span></p><p><b>name</b>: Testing Lab</p></div>
            </text>
            <identifier>
              <system value="urn:oid:2.16.840.1.113883.4.82"/>
              <value value="3007270600"/>
            </identifier>
            <active value="true"/>
            <type>
              <coding>
                <system
                        value="http://terminology.hl7.org/CodeSystem/pharmaceutical-organization-type"/>
                <code value="analytical-testing-release"/>
                <display value="Analytical Testing - Release"/>
              </coding>
            </type>
            <name value="Testing Lab"/>
          </Organization>
        </resource>
      </entry>
      <!--  Diagnostic report doesn't carry much extra value but does collect all the observations  -->
      <entry>
        <fullUrl value="urn:uuid:b664977d-799d-a1ce-928a-5def2a9955bd"/>
        <resource>
          <DiagnosticReport>
            <!--  ideally this wants a subject, but it can only be a Medication (batch) and we have multiple.
                         however the observations themselves do have subjects  -->
            <id value="processValidationReport"/>
            <text>
              <status value="extensions"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="DiagnosticReport_processValidationReport"> </a><p><b>Generated Narrative: DiagnosticReport</b><a name="processValidationReport"> </a><a name="hcprocessValidationReport"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource DiagnosticReport &quot;processValidationReport&quot; </p></div><p><b>Triggered by</b>: See on this page: PlanDefinition/2038e4c7-22b8-4c56-2d28-6c077648763f</p><p><b>status</b>: final</p><p><b>code</b>: Process Validation Report <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-pharmaceutical-report-type.html">Pharmaceutical Report Type Codes</a>#Process Validation Report)</span></p><p><b>effective</b>: 2020-12</p><p><b>result</b>: </p><ul><li>See on this page: Observation/9c56948a-2a39-6609-1c01-4d197ea57a33</li><li>See on this page: Observation/9c56948a-3a39-6609-1c01-4d197ea57a33</li><li>See on this page: Observation/9c56948a-4a39-6609-1c01-4d197ea57a33</li><li>See on this page: Observation/9c56948a-3a49-6609-1c01-4d197ea57a33</li><li>See on this page: Observation/9c56958a-4a39-6609-1c01-4d197ea57a33</li><li>See on this page: Observation/9c56948a-5a39-6609-1c01-4d197ea57a33</li><li>See on this page: Observation/9c56948a-2a39-6609-1c01-4d297ea57a33</li><li>See on this page: Observation/9c56948a-3a39-6619-1c01-4d197ea57a33</li><li>See on this page: Observation/9c56948a-4a39-6619-1c01-4d197ea57a33</li><li>See on this page: Observation/9c56948a-3a49-6619-1c01-4d197ea57a33</li><li>See on this page: Observation/9c56958a-4a39-6619-1c01-4d197ea57a33</li><li>See on this page: Observation/9c56948a-5a39-6709-1c01-4d197ea57a33</li><li>See on this page: Observation/f0a04328-905c-4ec5-372e-4d6cfef18629</li><li>See on this page: Observation/5e5a5e67-7fc6-0064-1be9-5d9d14d887e5</li><li>See on this page: Observation/cfde6776-673c-72e2-68c4-07b77cd85b74</li><li>See on this page: Observation/9c56948a-1a39-6609-1c01-4d197ea57a33</li><li>See on this page: Observation/1e20aed7-7626-1664-8d96-235f860d9a2c</li><li>See on this page: Observation/ec6d7e30-4d70-491b-0669-a613eedd3c60</li><li>See on this page: Observation/ab7997fa-7b46-1175-3f01-6f6997f7878a</li><li>See on this page: Observation/4052f28b-64a2-392d-35e4-ec8e912434d2</li><li>See on this page: Observation/34ebc51d-8105-0589-3c8d-e7aa6bd0a06c</li><li>See on this page: Observation/2940bf11-05bf-6ce2-3c64-457d0d1f9913</li><li>See on this page: Observation/332b1e76-6f70-2b4e-5d0c-f22a0e042d3e</li><li>See on this page: Observation/f0a13a3b-2e8b-594f-6874-6050511e4c57</li><li>See on this page: Observation/7fe7ccd7-6449-0186-2282-3eeb4cf6a795</li><li>See on this page: Observation/be016630-8754-7414-9014-21e020ad66c6</li><li>See on this page: Observation/92568f68-78f3-908c-6935-ff5f3d574dd6</li><li>See on this page: Observation/a0ba0f6d-8ec0-846a-a70d-f6bca6d01a12</li><li>See on this page: Observation/d8533dcb-03f8-5997-6ccf-4f9b6f7a5745</li><li>See on this page: Observation/7cec19a2-34a7-6b80-3d60-083b2cc64fcb</li><li>See on this page: Observation/27aa47fd-7964-4f96-6495-b2bec7f160e7</li><li>See on this page: Observation/6a78bcde-4781-226c-946e-a4b6915c1899</li><li>See on this page: Observation/f9f11088-7527-947c-3d3f-e71b32e13c78</li><li>See on this page: Observation/66c2f585-678e-78b8-2235-1a3b37bd6e46</li><li>See on this page: Observation/f8232d25-023d-679f-9c58-a6dc234b7a28</li><li>See on this page: Observation/368b82be-75dd-1d97-3dbc-a7eed9869daa</li><li>See on this page: Observation/44aa47fd-8964-4f96-6495-b2bec7f160e7</li><li>See on this page: Observation/45aa47fd-8964-4f96-6495-b2bec7f160e7</li><li>See on this page: Observation/45ab47fd-8964-4f96-6495-b2bec7f160e7</li><li>See on this page: Observation/37aa47fd-8964-4f96-6495-b2bec7f160e7</li><li>See on this page: Observation/38aa47fd-8964-4f96-6495-b2bec7f160e7</li><li>See on this page: Observation/38aa48fd-8964-4f96-6495-b2bec7f160e7</li><li>See on this page: Observation/37aa47fd-7964-4f96-6495-b2bec7f160e7</li><li>See on this page: Observation/47aa47fd-7964-4f96-6495-b2bec7f160e7</li><li>See on this page: Observation/47aa47fd-7964-4f96-6495-b2bec7f160e8</li><li>See on this page: Observation/47aa47fd-8964-4f96-6495-b2bec7f160e7</li><li>See on this page: Observation/47aa47fd-8964-5f96-6495-b2bec7f160e7</li></ul><p><b>conclusion</b>: The samples have been assessed and the conclusion is...</p></div>
            </text>
            <extension
                       url="http://hl7.org/fhir/StructureDefinition/workflow-triggeredBy">
              <valueReference>
                <!-- PlanDefinition/validationProtocol -->
                <reference
                           value="PlanDefinition/2038e4c7-22b8-4c56-2d28-6c077648763f"/>
              </valueReference>
            </extension>
            <status value="final"/>
            <code>
              <coding>
                <system
                        value="http://terminology.hl7.org/CodeSystem/pharmaceutical-report-type"/>
                <code value="Process Validation Report"/>
                <display value="Process Validation Report"/>
              </coding>
            </code>
            <effectiveDateTime value="2020-12"/>
            <result>
              <!-- Observation/compoundingpHPre1 -->
              <reference
                         value="Observation/9c56948a-2a39-6609-1c01-4d197ea57a33"/>
            </result>
            <result>
              <!-- Observation/compoundingpHPre2 -->
              <reference
                         value="Observation/9c56948a-3a39-6609-1c01-4d197ea57a33"/>
            </result>
            <result>
              <!-- Observation/compoundingpHPre3 -->
              <reference
                         value="Observation/9c56948a-4a39-6609-1c01-4d197ea57a33"/>
            </result>
            <result>
              <!-- Observation/compoundingpHPost1 -->
              <reference
                         value="Observation/9c56948a-3a49-6609-1c01-4d197ea57a33"/>
            </result>
            <result>
              <!-- Observation/compoundingpHPost2 -->
              <reference
                         value="Observation/9c56958a-4a39-6609-1c01-4d197ea57a33"/>
            </result>
            <result>
              <!-- Observation/compoundingpHPost3 -->
              <reference
                         value="Observation/9c56948a-5a39-6609-1c01-4d197ea57a33"/>
            </result>
            <result>
              <!-- Observation/compoundingAssayPre1 -->
              <reference
                         value="Observation/9c56948a-2a39-6609-1c01-4d297ea57a33"/>
            </result>
            <result>
              <!-- Observation/compoundingAssayPre2 -->
              <reference
                         value="Observation/9c56948a-3a39-6619-1c01-4d197ea57a33"/>
            </result>
            <result>
              <!-- Observation/compoundingAssayPre3 -->
              <reference
                         value="Observation/9c56948a-4a39-6619-1c01-4d197ea57a33"/>
            </result>
            <result>
              <!-- Observation/compoundingAssayPost1 -->
              <reference
                         value="Observation/9c56948a-3a49-6619-1c01-4d197ea57a33"/>
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            <result>
              <!-- Observation/compoundingAssayPost2 -->
              <reference
                         value="Observation/9c56958a-4a39-6619-1c01-4d197ea57a33"/>
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            <result>
              <!-- Observation/compoundingAssayPost3 -->
              <reference
                         value="Observation/9c56948a-5a39-6709-1c01-4d197ea57a33"/>
            </result>
            <result>
              <!-- Observation/observationIdentification -->
              <reference
                         value="Observation/f0a04328-905c-4ec5-372e-4d6cfef18629"/>
            </result>
            <result>
              <!-- Observation/observationIdentification2 -->
              <reference
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            <result>
              <!-- Observation/observationIdentification3 -->
              <reference
                         value="Observation/cfde6776-673c-72e2-68c4-07b77cd85b74"/>
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            <result>
              <!-- Observation/observationAssay -->
              <reference
                         value="Observation/9c56948a-1a39-6609-1c01-4d197ea57a33"/>
            </result>
            <result>
              <!-- Observation/observationAssay2 -->
              <reference
                         value="Observation/1e20aed7-7626-1664-8d96-235f860d9a2c"/>
            </result>
            <result>
              <!-- Observation/observationAssay3 -->
              <reference
                         value="Observation/ec6d7e30-4d70-491b-0669-a613eedd3c60"/>
            </result>
            <result>
              <!-- Observation/observationDegradation-imp1 -->
              <reference
                         value="Observation/ab7997fa-7b46-1175-3f01-6f6997f7878a"/>
            </result>
            <result>
              <!-- Observation/observationDegradation-imp1-2 -->
              <reference
                         value="Observation/4052f28b-64a2-392d-35e4-ec8e912434d2"/>
            </result>
            <result>
              <!-- Observation/observationDegradation-imp1-3 -->
              <reference
                         value="Observation/34ebc51d-8105-0589-3c8d-e7aa6bd0a06c"/>
            </result>
            <result>
              <!-- Observation/observationDegradation-imp2 -->
              <reference
                         value="Observation/2940bf11-05bf-6ce2-3c64-457d0d1f9913"/>
            </result>
            <result>
              <!-- Observation/observationDegradation-imp2-2 -->
              <reference
                         value="Observation/332b1e76-6f70-2b4e-5d0c-f22a0e042d3e"/>
            </result>
            <result>
              <!-- Observation/observationDegradation-imp2-3 -->
              <reference
                         value="Observation/f0a13a3b-2e8b-594f-6874-6050511e4c57"/>
            </result>
            <result>
              <!-- Observation/observationDegradation-imp3 -->
              <reference
                         value="Observation/7fe7ccd7-6449-0186-2282-3eeb4cf6a795"/>
            </result>
            <result>
              <!-- Observation/observationDegradation-imp3-2 -->
              <reference
                         value="Observation/be016630-8754-7414-9014-21e020ad66c6"/>
            </result>
            <result>
              <!-- Observation/observationDegradation-imp3-3 -->
              <reference
                         value="Observation/92568f68-78f3-908c-6935-ff5f3d574dd6"/>
            </result>
            <result>
              <!-- Observation/observationDegradation-imp-unspecified -->
              <reference
                         value="Observation/a0ba0f6d-8ec0-846a-a70d-f6bca6d01a12"/>
            </result>
            <result>
              <!-- Observation/observationDegradation-imp-unspecified-2 -->
              <reference
                         value="Observation/d8533dcb-03f8-5997-6ccf-4f9b6f7a5745"/>
            </result>
            <result>
              <!-- Observation/observationDegradation-imp-unspecified-3 -->
              <reference
                         value="Observation/7cec19a2-34a7-6b80-3d60-083b2cc64fcb"/>
            </result>
            <result>
              <!-- Observation/observationDegradation-imp-total -->
              <reference
                         value="Observation/27aa47fd-7964-4f96-6495-b2bec7f160e7"/>
            </result>
            <result>
              <!-- Observation/observationDegradation-imp-total-2 -->
              <reference
                         value="Observation/6a78bcde-4781-226c-946e-a4b6915c1899"/>
            </result>
            <result>
              <!-- Observation/observationDegradation-imp-total-3 -->
              <reference
                         value="Observation/f9f11088-7527-947c-3d3f-e71b32e13c78"/>
            </result>
            <result>
              <!-- Observation/observationWater -->
              <reference
                         value="Observation/66c2f585-678e-78b8-2235-1a3b37bd6e46"/>
            </result>
            <result>
              <!-- Observation/observationWater2 -->
              <reference
                         value="Observation/f8232d25-023d-679f-9c58-a6dc234b7a28"/>
            </result>
            <result>
              <!-- Observation/observationWater3 -->
              <reference
                         value="Observation/368b82be-75dd-1d97-3dbc-a7eed9869daa"/>
            </result>
            <result>
              <!-- Observation/fillingTAMC1 -->
              <reference
                         value="Observation/44aa47fd-8964-4f96-6495-b2bec7f160e7"/>
            </result>
            <result>
              <!-- Observation/fillingConclusion-nosubject -->
              <reference
                         value="Observation/45aa47fd-8964-4f96-6495-b2bec7f160e7"/>
            </result>
            <result>
              <!-- Observation/lyophilizationConclusion-nosubject -->
              <reference
                         value="Observation/45ab47fd-8964-4f96-6495-b2bec7f160e7"/>
            </result>
            <result>
              <!-- Observation/lyophilizerNumber1 -->
              <reference
                         value="Observation/37aa47fd-8964-4f96-6495-b2bec7f160e7"/>
            </result>
            <result>
              <!-- Observation/lyophilizerNumber2 -->
              <reference
                         value="Observation/38aa47fd-8964-4f96-6495-b2bec7f160e7"/>
            </result>
            <result>
              <!-- Observation/lyophilizerNumber3 -->
              <reference
                         value="Observation/38aa48fd-8964-4f96-6495-b2bec7f160e7"/>
            </result>
            <result>
              <!-- Observation/lyophilizationAssay1 -->
              <reference
                         value="Observation/37aa47fd-7964-4f96-6495-b2bec7f160e7"/>
            </result>
            <result>
              <!-- Observation/lyophilizationAssay2 -->
              <reference
                         value="Observation/47aa47fd-7964-4f96-6495-b2bec7f160e7"/>
            </result>
            <result>
              <!-- Observation/lyophilizationAssay3 -->
              <reference
                         value="Observation/47aa47fd-7964-4f96-6495-b2bec7f160e8"/>
            </result>
            <result>
              <!-- Observation/lyophilizerWaterHomogeneity1 -->
              <reference
                         value="Observation/47aa47fd-8964-4f96-6495-b2bec7f160e7"/>
            </result>
            <result>
              <!-- Observation/lyophilizerAssayHomogeneity1 -->
              <reference
                         value="Observation/47aa47fd-8964-5f96-6495-b2bec7f160e7"/>
            </result>
            <conclusion
                        value="The samples have been assessed and the conclusion is..."/>
          </DiagnosticReport>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:f0a04328-905c-4ec5-372e-4d6cfef18629"/>
        <resource>
          <Observation>
            <!-- observationIdentification -->
            <id value="f0a04328-905c-4ec5-372e-4d6cfef18629"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_f0a04328-905c-4ec5-372e-4d6cfef18629"> </a><p><b>Generated Narrative: Observation</b><a name="f0a04328-905c-4ec5-372e-4d6cfef18629"> </a><a name="hcf0a04328-905c-4ec5-372e-4d6cfef18629"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation &quot;f0a04328-905c-4ec5-372e-4d6cfef18629&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/3b0e878e-4bc9-8864-862f-e28b21233e8d</p><p><b>status</b>: final</p><p><b>code</b>: Identification <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#IDT)</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: Complies <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p></div>
            </text>
            <instantiatesReference>
              <!-- ObservationDefinition/Identification -->
              <reference
                         value="ObservationDefinition/3b0e878e-4bc9-8864-862f-e28b21233e8d"/>
            </instantiatesReference>
            <status value="final"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="IDT"/>
                <display value="Identification"/>
              </coding>
              <text value="Identification"/>
            </code>
            <subject>
              <!-- Medication/medication-batch-information-drug-pq-ex1 -->
              <reference value="Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"/>
            </subject>
            <effectiveDateTime value="2023-01-01T12:00:00Z"/>
            <performer>
              <!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
              <reference
                         value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
            </performer>
            <valueCodeableConcept>
              <text value="Complies"/>
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          </Observation>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:5e5a5e67-7fc6-0064-1be9-5d9d14d887e5"/>
        <resource>
          <Observation>
            <!-- observationIdentification2 -->
            <id value="5e5a5e67-7fc6-0064-1be9-5d9d14d887e5"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_5e5a5e67-7fc6-0064-1be9-5d9d14d887e5"> </a><p><b>Generated Narrative: Observation</b><a name="5e5a5e67-7fc6-0064-1be9-5d9d14d887e5"> </a><a name="hc5e5a5e67-7fc6-0064-1be9-5d9d14d887e5"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation &quot;5e5a5e67-7fc6-0064-1be9-5d9d14d887e5&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/3b0e878e-4bc9-8864-862f-e28b21233e8d</p><p><b>status</b>: final</p><p><b>code</b>: Identification <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#IDT)</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: Does not comply <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p></div>
            </text>
            <instantiatesReference>
              <!-- ObservationDefinition/Identification -->
              <reference
                         value="ObservationDefinition/3b0e878e-4bc9-8864-862f-e28b21233e8d"/>
            </instantiatesReference>
            <status value="final"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="IDT"/>
                <display value="Identification"/>
              </coding>
              <text value="Identification"/>
            </code>
            <subject>
              <!-- Medication/medication-actual-batch-2 -->
              <reference value="Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"/>
            </subject>
            <effectiveDateTime value="2023-01-01T12:00:00Z"/>
            <performer>
              <!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
              <reference
                         value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
            </performer>
            <valueCodeableConcept>
              <text value="Does not comply"/>
            </valueCodeableConcept>
          </Observation>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:cfde6776-673c-72e2-68c4-07b77cd85b74"/>
        <resource>
          <Observation>
            <!-- observationIdentification3 -->
            <id value="cfde6776-673c-72e2-68c4-07b77cd85b74"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_cfde6776-673c-72e2-68c4-07b77cd85b74"> </a><p><b>Generated Narrative: Observation</b><a name="cfde6776-673c-72e2-68c4-07b77cd85b74"> </a><a name="hccfde6776-673c-72e2-68c4-07b77cd85b74"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation &quot;cfde6776-673c-72e2-68c4-07b77cd85b74&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/3b0e878e-4bc9-8864-862f-e28b21233e8d</p><p><b>status</b>: final</p><p><b>code</b>: Identification <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#IDT)</span></p><p><b>subject</b>: See on this page: Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: Complies <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p></div>
            </text>
            <instantiatesReference>
              <!-- ObservationDefinition/Identification -->
              <reference
                         value="ObservationDefinition/3b0e878e-4bc9-8864-862f-e28b21233e8d"/>
            </instantiatesReference>
            <status value="final"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="IDT"/>
                <display value="Identification"/>
              </coding>
              <text value="Identification"/>
            </code>
            <subject>
              <!-- Medication/medication-actual-batch-3 -->
              <reference value="Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"/>
            </subject>
            <effectiveDateTime value="2023-01-01T12:00:00Z"/>
            <performer>
              <!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
              <reference
                         value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
            </performer>
            <valueCodeableConcept>
              <text value="Complies"/>
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          </Observation>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:9c56948a-2a39-6609-1c01-4d197ea57a33"/>
        <resource>
          <Observation>
            <!-- compoundingpHPre1 -->
            <id value="9c56948a-2a39-6609-1c01-4d197ea57a33"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_9c56948a-2a39-6609-1c01-4d197ea57a33"> </a><p><b>Generated Narrative: Observation</b><a name="9c56948a-2a39-6609-1c01-4d197ea57a33"> </a><a name="hc9c56948a-2a39-6609-1c01-4d197ea57a33"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation &quot;9c56948a-2a39-6609-1c01-4d197ea57a33&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e72</p><p><b>status</b>: final</p><p><b>code</b>: pH (adjustment of pre-clarification bulk solution) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#pH (adjustment of pre-clarification bulk solution))</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 6.91 pH<span style="background: LightGoldenRodYellow"> (Details: UCUM code pH = 'pH')</span></p></div>
            </text>
            <instantiatesReference>
              <!-- ObservationDefinition/compoundingpHPre -->
              <reference
                         value="ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e72"/>
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            <status value="final"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="pH (adjustment of pre-clarification bulk solution)"/>
                <display
                         value="pH (adjustment of pre-clarification bulk solution)"/>
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              <text value="pH (adjustment of pre-clarification bulk solution)"/>
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            <subject>
              <!-- Medication/medication-batch-information-drug-pq-ex1 -->
              <reference value="Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"/>
            </subject>
            <effectiveDateTime value="2023-01-01T12:00:00Z"/>
            <performer>
              <!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
              <reference
                         value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
            </performer>
            <valueQuantity>
              <value value="6.91"/>
              <unit value="pH"/>
              <system value="http://unitsofmeasure.org"/>
              <code value="pH"/>
            </valueQuantity>
          </Observation>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:9c56948a-3a39-6609-1c01-4d197ea57a33"/>
        <resource>
          <Observation>
            <!-- compoundingpHPre2 -->
            <id value="9c56948a-3a39-6609-1c01-4d197ea57a33"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_9c56948a-3a39-6609-1c01-4d197ea57a33"> </a><p><b>Generated Narrative: Observation</b><a name="9c56948a-3a39-6609-1c01-4d197ea57a33"> </a><a name="hc9c56948a-3a39-6609-1c01-4d197ea57a33"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation &quot;9c56948a-3a39-6609-1c01-4d197ea57a33&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e72</p><p><b>status</b>: final</p><p><b>code</b>: pH (adjustment of pre-clarification bulk solution) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#pH (adjustment of pre-clarification bulk solution))</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 6.92 pH<span style="background: LightGoldenRodYellow"> (Details: UCUM code pH = 'pH')</span></p></div>
            </text>
            <instantiatesReference>
              <!-- ObservationDefinition/compoundingpHPre -->
              <reference
                         value="ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e72"/>
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            <status value="final"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="pH (adjustment of pre-clarification bulk solution)"/>
                <display
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              </coding>
              <text value="pH (adjustment of pre-clarification bulk solution)"/>
            </code>
            <subject>
              <!-- Medication/medication-actual-batch-2 -->
              <reference value="Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"/>
            </subject>
            <effectiveDateTime value="2023-01-01T12:00:00Z"/>
            <performer>
              <!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
              <reference
                         value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
            </performer>
            <valueQuantity>
              <value value="6.92"/>
              <unit value="pH"/>
              <system value="http://unitsofmeasure.org"/>
              <code value="pH"/>
            </valueQuantity>
          </Observation>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:9c56948a-4a39-6609-1c01-4d197ea57a33"/>
        <resource>
          <Observation>
            <!-- compoundingpHPre3 -->
            <id value="9c56948a-4a39-6609-1c01-4d197ea57a33"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_9c56948a-4a39-6609-1c01-4d197ea57a33"> </a><p><b>Generated Narrative: Observation</b><a name="9c56948a-4a39-6609-1c01-4d197ea57a33"> </a><a name="hc9c56948a-4a39-6609-1c01-4d197ea57a33"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation &quot;9c56948a-4a39-6609-1c01-4d197ea57a33&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e72</p><p><b>status</b>: final</p><p><b>code</b>: pH (adjustment of pre-clarification bulk solution) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#pH (adjustment of pre-clarification bulk solution))</span></p><p><b>subject</b>: See on this page: Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 6.93 pH<span style="background: LightGoldenRodYellow"> (Details: UCUM code pH = 'pH')</span></p></div>
            </text>
            <instantiatesReference>
              <!-- ObservationDefinition/compoundingpHPre -->
              <reference
                         value="ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e72"/>
            </instantiatesReference>
            <status value="final"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="pH (adjustment of pre-clarification bulk solution)"/>
                <display
                         value="pH (adjustment of pre-clarification bulk solution)"/>
              </coding>
              <text value="pH (adjustment of pre-clarification bulk solution)"/>
            </code>
            <subject>
              <!-- Medication/medication-actual-batch-3 -->
              <reference value="Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"/>
            </subject>
            <effectiveDateTime value="2023-01-01T12:00:00Z"/>
            <performer>
              <!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
              <reference
                         value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
            </performer>
            <valueQuantity>
              <value value="6.93"/>
              <unit value="pH"/>
              <system value="http://unitsofmeasure.org"/>
              <code value="pH"/>
            </valueQuantity>
          </Observation>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:9c56948a-3a49-6609-1c01-4d197ea57a33"/>
        <resource>
          <Observation>
            <!-- compoundingpHPost1 -->
            <id value="9c56948a-3a49-6609-1c01-4d197ea57a33"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_9c56948a-3a49-6609-1c01-4d197ea57a33"> </a><p><b>Generated Narrative: Observation</b><a name="9c56948a-3a49-6609-1c01-4d197ea57a33"> </a><a name="hc9c56948a-3a49-6609-1c01-4d197ea57a33"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation &quot;9c56948a-3a49-6609-1c01-4d197ea57a33&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e73</p><p><b>status</b>: final</p><p><b>code</b>: pH (adjustment of pre-clarification bulk solution) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#pH (adjustment of pre-clarification bulk solution))</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 7.01 pH<span style="background: LightGoldenRodYellow"> (Details: UCUM code pH = 'pH')</span></p></div>
            </text>
            <instantiatesReference>
              <!-- ObservationDefinition/compoundingpHPost -->
              <reference
                         value="ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e73"/>
            </instantiatesReference>
            <status value="final"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="pH (adjustment of pre-clarification bulk solution)"/>
                <display
                         value="pH (adjustment of pre-clarification bulk solution)"/>
              </coding>
              <text value="pH (adjustment of pre-clarification bulk solution)"/>
            </code>
            <subject>
              <!-- Medication/medication-batch-information-drug-pq-ex1 -->
              <reference value="Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"/>
            </subject>
            <effectiveDateTime value="2023-01-01T12:00:00Z"/>
            <performer>
              <!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
              <reference
                         value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
            </performer>
            <valueQuantity>
              <value value="7.01"/>
              <unit value="pH"/>
              <system value="http://unitsofmeasure.org"/>
              <code value="pH"/>
            </valueQuantity>
          </Observation>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:9c56958a-4a39-6609-1c01-4d197ea57a33"/>
        <resource>
          <Observation>
            <!-- compoundingpHPost2 -->
            <id value="9c56958a-4a39-6609-1c01-4d197ea57a33"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_9c56958a-4a39-6609-1c01-4d197ea57a33"> </a><p><b>Generated Narrative: Observation</b><a name="9c56958a-4a39-6609-1c01-4d197ea57a33"> </a><a name="hc9c56958a-4a39-6609-1c01-4d197ea57a33"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation &quot;9c56958a-4a39-6609-1c01-4d197ea57a33&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e73</p><p><b>status</b>: final</p><p><b>code</b>: pH (adjustment of pre-clarification bulk solution) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#pH (adjustment of pre-clarification bulk solution))</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 7.02 pH<span style="background: LightGoldenRodYellow"> (Details: UCUM code pH = 'pH')</span></p></div>
            </text>
            <instantiatesReference>
              <!-- ObservationDefinition/compoundingpHPost -->
              <reference
                         value="ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e73"/>
            </instantiatesReference>
            <status value="final"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="pH (adjustment of pre-clarification bulk solution)"/>
                <display
                         value="pH (adjustment of pre-clarification bulk solution)"/>
              </coding>
              <text value="pH (adjustment of pre-clarification bulk solution)"/>
            </code>
            <subject>
              <!-- Medication/medication-actual-batch-2 -->
              <reference value="Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"/>
            </subject>
            <effectiveDateTime value="2023-01-01T12:00:00Z"/>
            <performer>
              <!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
              <reference
                         value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
            </performer>
            <valueQuantity>
              <value value="7.02"/>
              <unit value="pH"/>
              <system value="http://unitsofmeasure.org"/>
              <code value="pH"/>
            </valueQuantity>
          </Observation>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:9c56948a-5a39-6609-1c01-4d197ea57a33"/>
        <resource>
          <Observation>
            <!-- compoundingpHPost3 -->
            <id value="9c56948a-5a39-6609-1c01-4d197ea57a33"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_9c56948a-5a39-6609-1c01-4d197ea57a33"> </a><p><b>Generated Narrative: Observation</b><a name="9c56948a-5a39-6609-1c01-4d197ea57a33"> </a><a name="hc9c56948a-5a39-6609-1c01-4d197ea57a33"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation &quot;9c56948a-5a39-6609-1c01-4d197ea57a33&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e73</p><p><b>status</b>: final</p><p><b>code</b>: pH (adjustment of pre-clarification bulk solution) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#pH (adjustment of pre-clarification bulk solution))</span></p><p><b>subject</b>: See on this page: Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 6.93 pH<span style="background: LightGoldenRodYellow"> (Details: UCUM code pH = 'pH')</span></p></div>
            </text>
            <instantiatesReference>
              <!-- ObservationDefinition/compoundingpHPost -->
              <reference
                         value="ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e73"/>
            </instantiatesReference>
            <status value="final"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="pH (adjustment of pre-clarification bulk solution)"/>
                <display
                         value="pH (adjustment of pre-clarification bulk solution)"/>
              </coding>
              <text value="pH (adjustment of pre-clarification bulk solution)"/>
            </code>
            <subject>
              <!-- Medication/medication-actual-batch-3 -->
              <reference value="Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"/>
            </subject>
            <effectiveDateTime value="2023-01-01T12:00:00Z"/>
            <performer>
              <!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
              <reference
                         value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
            </performer>
            <valueQuantity>
              <value value="6.93"/>
              <unit value="pH"/>
              <system value="http://unitsofmeasure.org"/>
              <code value="pH"/>
            </valueQuantity>
          </Observation>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:9c56948a-2a39-6609-1c01-4d297ea57a33"/>
        <resource>
          <Observation>
            <!-- compoundingAssayPre1 -->
            <id value="9c56948a-2a39-6609-1c01-4d297ea57a33"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_9c56948a-2a39-6609-1c01-4d297ea57a33"> </a><p><b>Generated Narrative: Observation</b><a name="9c56948a-2a39-6609-1c01-4d297ea57a33"> </a><a name="hc9c56948a-2a39-6609-1c01-4d297ea57a33"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation &quot;9c56948a-2a39-6609-1c01-4d297ea57a33&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/fd17b5d5-9fe1-91c2-2d06-47cb5b295e72</p><p><b>status</b>: final</p><p><b>code</b>: Assay (pre-clarification filtration) (mg/mL) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#Assay (pre-clarification filtration) (mg/mL))</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 21.1 mg/mL<span style="background: LightGoldenRodYellow"> (Details: UCUM code mg/mL = 'mg/mL')</span></p></div>
            </text>
            <instantiatesReference>
              <!-- ObservationDefinition/compoundingAssayPre -->
              <reference
                         value="ObservationDefinition/fd17b5d5-9fe1-91c2-2d06-47cb5b295e72"/>
            </instantiatesReference>
            <status value="final"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="Assay (pre-clarification filtration) (mg/mL)"/>
                <display value="Assay (pre-clarification filtration) (mg/mL)"/>
              </coding>
              <text value="Assay (pre-clarification filtration) (mg/mL)"/>
            </code>
            <subject>
              <!-- Medication/medication-batch-information-drug-pq-ex1 -->
              <reference value="Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"/>
            </subject>
            <effectiveDateTime value="2023-01-01T12:00:00Z"/>
            <performer>
              <!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
              <reference
                         value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
            </performer>
            <valueQuantity>
              <value value="21.1"/>
              <unit value="mg/mL"/>
              <system value="http://unitsofmeasure.org"/>
              <code value="mg/mL"/>
            </valueQuantity>
          </Observation>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:9c56948a-3a39-6619-1c01-4d197ea57a33"/>
        <resource>
          <Observation>
            <!-- compoundingAssayPre2 -->
            <id value="9c56948a-3a39-6619-1c01-4d197ea57a33"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_9c56948a-3a39-6619-1c01-4d197ea57a33"> </a><p><b>Generated Narrative: Observation</b><a name="9c56948a-3a39-6619-1c01-4d197ea57a33"> </a><a name="hc9c56948a-3a39-6619-1c01-4d197ea57a33"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation &quot;9c56948a-3a39-6619-1c01-4d197ea57a33&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/fd17b5d5-9fe1-91c2-2d06-47cb5b295e72</p><p><b>status</b>: final</p><p><b>code</b>: Assay (pre-clarification filtration) (mg/mL) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#Assay (pre-clarification filtration) (mg/mL))</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 21.2 mg/mL<span style="background: LightGoldenRodYellow"> (Details: UCUM code mg/mL = 'mg/mL')</span></p></div>
            </text>
            <instantiatesReference>
              <!-- ObservationDefinition/compoundingAssayPre -->
              <reference
                         value="ObservationDefinition/fd17b5d5-9fe1-91c2-2d06-47cb5b295e72"/>
            </instantiatesReference>
            <status value="final"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="Assay (pre-clarification filtration) (mg/mL)"/>
                <display value="Assay (pre-clarification filtration) (mg/mL)"/>
              </coding>
              <text value="Assay (pre-clarification filtration) (mg/mL)"/>
            </code>
            <subject>
              <!-- Medication/medication-actual-batch-2 -->
              <reference value="Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"/>
            </subject>
            <effectiveDateTime value="2023-01-01T12:00:00Z"/>
            <performer>
              <!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
              <reference
                         value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
            </performer>
            <valueQuantity>
              <value value="21.2"/>
              <unit value="mg/mL"/>
              <system value="http://unitsofmeasure.org"/>
              <code value="mg/mL"/>
            </valueQuantity>
          </Observation>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:9c56948a-4a39-6619-1c01-4d197ea57a33"/>
        <resource>
          <Observation>
            <!-- compoundingAssayPre3 -->
            <id value="9c56948a-4a39-6619-1c01-4d197ea57a33"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_9c56948a-4a39-6619-1c01-4d197ea57a33"> </a><p><b>Generated Narrative: Observation</b><a name="9c56948a-4a39-6619-1c01-4d197ea57a33"> </a><a name="hc9c56948a-4a39-6619-1c01-4d197ea57a33"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation &quot;9c56948a-4a39-6619-1c01-4d197ea57a33&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/fd17b5d5-9fe1-91c2-2d06-47cb5b295e72</p><p><b>status</b>: final</p><p><b>code</b>: Assay (pre-clarification filtration) (mg/mL) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#Assay (pre-clarification filtration) (mg/mL))</span></p><p><b>subject</b>: See on this page: Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 21.3 mg/mL<span style="background: LightGoldenRodYellow"> (Details: UCUM code mg/mL = 'mg/mL')</span></p></div>
            </text>
            <instantiatesReference>
              <!-- ObservationDefinition/compoundingAssayPre -->
              <reference
                         value="ObservationDefinition/fd17b5d5-9fe1-91c2-2d06-47cb5b295e72"/>
            </instantiatesReference>
            <status value="final"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="Assay (pre-clarification filtration) (mg/mL)"/>
                <display value="Assay (pre-clarification filtration) (mg/mL)"/>
              </coding>
              <text value="Assay (pre-clarification filtration) (mg/mL)"/>
            </code>
            <subject>
              <!-- Medication/medication-actual-batch-3 -->
              <reference value="Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"/>
            </subject>
            <effectiveDateTime value="2023-01-01T12:00:00Z"/>
            <performer>
              <!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
              <reference
                         value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
            </performer>
            <valueQuantity>
              <value value="21.3"/>
              <unit value="mg/mL"/>
              <system value="http://unitsofmeasure.org"/>
              <code value="mg/mL"/>
            </valueQuantity>
          </Observation>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:9c56948a-3a49-6619-1c01-4d197ea57a33"/>
        <resource>
          <Observation>
            <!-- compoundingAssayPost1 -->
            <id value="9c56948a-3a49-6619-1c01-4d197ea57a33"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_9c56948a-3a49-6619-1c01-4d197ea57a33"> </a><p><b>Generated Narrative: Observation</b><a name="9c56948a-3a49-6619-1c01-4d197ea57a33"> </a><a name="hc9c56948a-3a49-6619-1c01-4d197ea57a33"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation &quot;9c56948a-3a49-6619-1c01-4d197ea57a33&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/fd17b5d5-9fe1-91c2-2d06-47cb5b295e73</p><p><b>status</b>: final</p><p><b>code</b>: Assay (Post dilution bulk solution) (mg/mL) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#Assay (Post dilution bulk solution) (mg/mL))</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 20.1 mg/mL<span style="background: LightGoldenRodYellow"> (Details: UCUM code mg/mL = 'mg/mL')</span></p></div>
            </text>
            <instantiatesReference>
              <!-- ObservationDefinition/compoundingAssayPost -->
              <reference
                         value="ObservationDefinition/fd17b5d5-9fe1-91c2-2d06-47cb5b295e73"/>
            </instantiatesReference>
            <status value="final"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="Assay (Post dilution bulk solution) (mg/mL)"/>
                <display value="Assay (Post dilution bulk solution) (mg/mL)"/>
              </coding>
              <text value="Assay (Post dilution bulk solution) (mg/mL)"/>
            </code>
            <subject>
              <!-- Medication/medication-batch-information-drug-pq-ex1 -->
              <reference value="Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"/>
            </subject>
            <effectiveDateTime value="2023-01-01T12:00:00Z"/>
            <performer>
              <!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
              <reference
                         value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
            </performer>
            <valueQuantity>
              <value value="20.1"/>
              <unit value="mg/mL"/>
              <system value="http://unitsofmeasure.org"/>
              <code value="mg/mL"/>
            </valueQuantity>
          </Observation>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:9c56958a-4a39-6619-1c01-4d197ea57a33"/>
        <resource>
          <Observation>
            <!-- compoundingAssayPost2 -->
            <id value="9c56958a-4a39-6619-1c01-4d197ea57a33"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_9c56958a-4a39-6619-1c01-4d197ea57a33"> </a><p><b>Generated Narrative: Observation</b><a name="9c56958a-4a39-6619-1c01-4d197ea57a33"> </a><a name="hc9c56958a-4a39-6619-1c01-4d197ea57a33"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation &quot;9c56958a-4a39-6619-1c01-4d197ea57a33&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/fd17b5d5-9fe1-91c2-2d06-47cb5b295e73</p><p><b>status</b>: final</p><p><b>code</b>: Assay (Post dilution bulk solution) (mg/mL) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#Assay (Post dilution bulk solution) (mg/mL))</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 20.2 mg/mL<span style="background: LightGoldenRodYellow"> (Details: UCUM code mg/mL = 'mg/mL')</span></p></div>
            </text>
            <instantiatesReference>
              <!-- ObservationDefinition/compoundingAssayPost -->
              <reference
                         value="ObservationDefinition/fd17b5d5-9fe1-91c2-2d06-47cb5b295e73"/>
            </instantiatesReference>
            <status value="final"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="Assay (Post dilution bulk solution) (mg/mL)"/>
                <display value="Assay (Post dilution bulk solution) (mg/mL)"/>
              </coding>
              <text value="Assay (Post dilution bulk solution) (mg/mL)"/>
            </code>
            <subject>
              <!-- Medication/medication-actual-batch-2 -->
              <reference value="Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"/>
            </subject>
            <effectiveDateTime value="2023-01-01T12:00:00Z"/>
            <performer>
              <!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
              <reference
                         value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
            </performer>
            <valueQuantity>
              <value value="20.2"/>
              <unit value="mg/mL"/>
              <system value="http://unitsofmeasure.org"/>
              <code value="mg/mL"/>
            </valueQuantity>
          </Observation>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:9c56948a-5a39-6709-1c01-4d197ea57a33"/>
        <resource>
          <Observation>
            <!-- compoundingAssayPost3 -->
            <id value="9c56948a-5a39-6709-1c01-4d197ea57a33"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_9c56948a-5a39-6709-1c01-4d197ea57a33"> </a><p><b>Generated Narrative: Observation</b><a name="9c56948a-5a39-6709-1c01-4d197ea57a33"> </a><a name="hc9c56948a-5a39-6709-1c01-4d197ea57a33"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation &quot;9c56948a-5a39-6709-1c01-4d197ea57a33&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/fd17b5d5-9fe1-91c2-2d06-47cb5b295e73</p><p><b>status</b>: final</p><p><b>code</b>: Assay (Post dilution bulk solution) (mg/mL) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#Assay (Post dilution bulk solution) (mg/mL))</span></p><p><b>subject</b>: See on this page: Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 20.3 mg/mL<span style="background: LightGoldenRodYellow"> (Details: UCUM code mg/mL = 'mg/mL')</span></p></div>
            </text>
            <instantiatesReference>
              <!-- ObservationDefinition/compoundingAssayPost -->
              <reference
                         value="ObservationDefinition/fd17b5d5-9fe1-91c2-2d06-47cb5b295e73"/>
            </instantiatesReference>
            <status value="final"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="Assay (Post dilution bulk solution) (mg/mL)"/>
                <display value="Assay (Post dilution bulk solution) (mg/mL)"/>
              </coding>
              <text value="Assay (Post dilution bulk solution) (mg/mL)"/>
            </code>
            <subject>
              <!-- Medication/medication-actual-batch-3 -->
              <reference value="Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"/>
            </subject>
            <effectiveDateTime value="2023-01-01T12:00:00Z"/>
            <performer>
              <!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
              <reference
                         value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
            </performer>
            <valueQuantity>
              <value value="20.3"/>
              <unit value="mg/mL"/>
              <system value="http://unitsofmeasure.org"/>
              <code value="mg/mL"/>
            </valueQuantity>
          </Observation>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:9c56948a-1a39-6609-1c01-4d197ea57a33"/>
        <resource>
          <Observation>
            <!-- observationAssay -->
            <id value="9c56948a-1a39-6609-1c01-4d197ea57a33"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_9c56948a-1a39-6609-1c01-4d197ea57a33"> </a><p><b>Generated Narrative: Observation</b><a name="9c56948a-1a39-6609-1c01-4d197ea57a33"> </a><a name="hc9c56948a-1a39-6609-1c01-4d197ea57a33"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation &quot;9c56948a-1a39-6609-1c01-4d197ea57a33&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/12e7e672-40a6-4036-3c1f-b8ba6a7d045e</p><p><b>status</b>: final</p><p><b>code</b>: Assay <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#ASSAY)</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 103 %<span style="background: LightGoldenRodYellow"> (Details: UCUM code % = '%')</span></p></div>
            </text>
            <instantiatesReference>
              <!-- ObservationDefinition/Assay -->
              <reference
                         value="ObservationDefinition/12e7e672-40a6-4036-3c1f-b8ba6a7d045e"/>
            </instantiatesReference>
            <status value="final"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="ASSAY"/>
                <display value="Assay"/>
              </coding>
              <text value="Assay"/>
            </code>
            <subject>
              <!-- Medication/medication-batch-information-drug-pq-ex1 -->
              <reference value="Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"/>
            </subject>
            <effectiveDateTime value="2023-01-01T12:00:00Z"/>
            <performer>
              <!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
              <reference
                         value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
            </performer>
            <valueQuantity>
              <value value="103"/>
              <unit value="%"/>
              <system value="http://unitsofmeasure.org"/>
              <code value="%"/>
            </valueQuantity>
          </Observation>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:1e20aed7-7626-1664-8d96-235f860d9a2c"/>
        <resource>
          <Observation>
            <!-- observationAssay2 -->
            <id value="1e20aed7-7626-1664-8d96-235f860d9a2c"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_1e20aed7-7626-1664-8d96-235f860d9a2c"> </a><p><b>Generated Narrative: Observation</b><a name="1e20aed7-7626-1664-8d96-235f860d9a2c"> </a><a name="hc1e20aed7-7626-1664-8d96-235f860d9a2c"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation &quot;1e20aed7-7626-1664-8d96-235f860d9a2c&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/12e7e672-40a6-4036-3c1f-b8ba6a7d045e</p><p><b>status</b>: final</p><p><b>code</b>: Assay <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#ASSAY)</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 102 %<span style="background: LightGoldenRodYellow"> (Details: UCUM code % = '%')</span></p></div>
            </text>
            <instantiatesReference>
              <!-- ObservationDefinition/Assay -->
              <reference
                         value="ObservationDefinition/12e7e672-40a6-4036-3c1f-b8ba6a7d045e"/>
            </instantiatesReference>
            <status value="final"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="ASSAY"/>
                <display value="Assay"/>
              </coding>
              <text value="Assay"/>
            </code>
            <subject>
              <!-- Medication/medication-actual-batch-2 -->
              <reference value="Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"/>
            </subject>
            <effectiveDateTime value="2023-01-01T12:00:00Z"/>
            <performer>
              <!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
              <reference
                         value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
            </performer>
            <valueQuantity>
              <value value="102"/>
              <unit value="%"/>
              <system value="http://unitsofmeasure.org"/>
              <code value="%"/>
            </valueQuantity>
          </Observation>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:ec6d7e30-4d70-491b-0669-a613eedd3c60"/>
        <resource>
          <Observation>
            <!-- observationAssay3 -->
            <id value="ec6d7e30-4d70-491b-0669-a613eedd3c60"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_ec6d7e30-4d70-491b-0669-a613eedd3c60"> </a><p><b>Generated Narrative: Observation</b><a name="ec6d7e30-4d70-491b-0669-a613eedd3c60"> </a><a name="hcec6d7e30-4d70-491b-0669-a613eedd3c60"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation &quot;ec6d7e30-4d70-491b-0669-a613eedd3c60&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/12e7e672-40a6-4036-3c1f-b8ba6a7d045e</p><p><b>status</b>: final</p><p><b>code</b>: Assay <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#ASSAY)</span></p><p><b>subject</b>: See on this page: Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 101 %<span style="background: LightGoldenRodYellow"> (Details: UCUM code % = '%')</span></p></div>
            </text>
            <instantiatesReference>
              <!-- ObservationDefinition/Assay -->
              <reference
                         value="ObservationDefinition/12e7e672-40a6-4036-3c1f-b8ba6a7d045e"/>
            </instantiatesReference>
            <status value="final"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="ASSAY"/>
                <display value="Assay"/>
              </coding>
              <text value="Assay"/>
            </code>
            <subject>
              <!-- Medication/medication-actual-batch-3 -->
              <reference value="Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"/>
            </subject>
            <effectiveDateTime value="2023-01-01T12:00:00Z"/>
            <performer>
              <!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
              <reference
                         value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
            </performer>
            <valueQuantity>
              <value value="101"/>
              <unit value="%"/>
              <system value="http://unitsofmeasure.org"/>
              <code value="%"/>
            </valueQuantity>
          </Observation>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:ab7997fa-7b46-1175-3f01-6f6997f7878a"/>
        <resource>
          <Observation>
            <!-- observationDegradation-imp1 -->
            <id value="ab7997fa-7b46-1175-3f01-6f6997f7878a"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_ab7997fa-7b46-1175-3f01-6f6997f7878a"> </a><p><b>Generated Narrative: Observation</b><a name="ab7997fa-7b46-1175-3f01-6f6997f7878a"> </a><a name="hcab7997fa-7b46-1175-3f01-6f6997f7878a"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation &quot;ab7997fa-7b46-1175-3f01-6f6997f7878a&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.1 % w/w<span style="background: LightGoldenRodYellow"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Impurity <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 1 <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></td></tr></table></div>
            </text>
            <instantiatesReference>
              <!-- ObservationDefinition/Degradation -->
              <reference
                         value="ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf"/>
            </instantiatesReference>
            <status value="final"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="DGP"/>
                <display value="Degradation Products"/>
              </coding>
              <text value="Degradation Products"/>
            </code>
            <subject>
              <!-- Medication/medication-batch-information-drug-pq-ex1 -->
              <reference value="Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"/>
            </subject>
            <effectiveDateTime value="2023-01-01T12:00:00Z"/>
            <performer>
              <!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
              <reference
                         value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
            </performer>
            <valueQuantity>
              <value value="0.1"/>
              <unit value="% w/w"/>
              <system value="http://unitsofmeasure.org"/>
              <code value="%"/>
            </valueQuantity>
            <component>
              <code>
                <coding>
                  <system
                          value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                  <code value="IMP"/>
                  <display value="Impurity"/>
                </coding>
              </code>
              <valueCodeableConcept>
                <!--  could have the code of an impurity substance, or could have an extension to point to it as a resource  -->
                <text value="Impurity 1"/>
              </valueCodeableConcept>
            </component>
          </Observation>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:4052f28b-64a2-392d-35e4-ec8e912434d2"/>
        <resource>
          <Observation>
            <!-- observationDegradation-imp1-2 -->
            <id value="4052f28b-64a2-392d-35e4-ec8e912434d2"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_4052f28b-64a2-392d-35e4-ec8e912434d2"> </a><p><b>Generated Narrative: Observation</b><a name="4052f28b-64a2-392d-35e4-ec8e912434d2"> </a><a name="hc4052f28b-64a2-392d-35e4-ec8e912434d2"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation &quot;4052f28b-64a2-392d-35e4-ec8e912434d2&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.2 % w/w<span style="background: LightGoldenRodYellow"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Impurity <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 1 <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></td></tr></table></div>
            </text>
            <instantiatesReference>
              <!-- ObservationDefinition/Degradation -->
              <reference
                         value="ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf"/>
            </instantiatesReference>
            <status value="final"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="DGP"/>
                <display value="Degradation Products"/>
              </coding>
              <text value="Degradation Products"/>
            </code>
            <subject>
              <!-- Medication/medication-actual-batch-2 -->
              <reference value="Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"/>
            </subject>
            <effectiveDateTime value="2023-01-01T12:00:00Z"/>
            <performer>
              <!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
              <reference
                         value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
            </performer>
            <valueQuantity>
              <value value="0.2"/>
              <unit value="% w/w"/>
              <system value="http://unitsofmeasure.org"/>
              <code value="%"/>
            </valueQuantity>
            <component>
              <code>
                <coding>
                  <system
                          value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                  <code value="IMP"/>
                  <display value="Impurity"/>
                </coding>
              </code>
              <valueCodeableConcept>
                <!--  could have the code of an impurity substance, or could have an extension to point to it as a resource  -->
                <text value="Impurity 1"/>
              </valueCodeableConcept>
            </component>
          </Observation>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:34ebc51d-8105-0589-3c8d-e7aa6bd0a06c"/>
        <resource>
          <Observation>
            <!-- observationDegradation-imp1-3 -->
            <id value="34ebc51d-8105-0589-3c8d-e7aa6bd0a06c"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_34ebc51d-8105-0589-3c8d-e7aa6bd0a06c"> </a><p><b>Generated Narrative: Observation</b><a name="34ebc51d-8105-0589-3c8d-e7aa6bd0a06c"> </a><a name="hc34ebc51d-8105-0589-3c8d-e7aa6bd0a06c"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation &quot;34ebc51d-8105-0589-3c8d-e7aa6bd0a06c&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.2 % w/w<span style="background: LightGoldenRodYellow"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Impurity <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 1 <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></td></tr></table></div>
            </text>
            <instantiatesReference>
              <!-- ObservationDefinition/Degradation -->
              <reference
                         value="ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf"/>
            </instantiatesReference>
            <status value="final"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="DGP"/>
                <display value="Degradation Products"/>
              </coding>
              <text value="Degradation Products"/>
            </code>
            <subject>
              <!-- Medication/medication-actual-batch-3 -->
              <reference value="Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"/>
            </subject>
            <effectiveDateTime value="2023-01-01T12:00:00Z"/>
            <performer>
              <!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
              <reference
                         value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
            </performer>
            <valueQuantity>
              <value value="0.2"/>
              <unit value="% w/w"/>
              <system value="http://unitsofmeasure.org"/>
              <code value="%"/>
            </valueQuantity>
            <component>
              <code>
                <coding>
                  <system
                          value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                  <code value="IMP"/>
                  <display value="Impurity"/>
                </coding>
              </code>
              <valueCodeableConcept>
                <!--  could have the code of an impurity substance, or could have an extension to point to it as a resource  -->
                <text value="Impurity 1"/>
              </valueCodeableConcept>
            </component>
          </Observation>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:2940bf11-05bf-6ce2-3c64-457d0d1f9913"/>
        <resource>
          <Observation>
            <!-- observationDegradation-imp2 -->
            <id value="2940bf11-05bf-6ce2-3c64-457d0d1f9913"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_2940bf11-05bf-6ce2-3c64-457d0d1f9913"> </a><p><b>Generated Narrative: Observation</b><a name="2940bf11-05bf-6ce2-3c64-457d0d1f9913"> </a><a name="hc2940bf11-05bf-6ce2-3c64-457d0d1f9913"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation &quot;2940bf11-05bf-6ce2-3c64-457d0d1f9913&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.2 % w/w<span style="background: LightGoldenRodYellow"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Impurity <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 2 <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></td></tr></table></div>
            </text>
            <instantiatesReference>
              <!-- ObservationDefinition/Degradation -->
              <reference
                         value="ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf"/>
            </instantiatesReference>
            <status value="final"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="DGP"/>
                <display value="Degradation Products"/>
              </coding>
              <text value="Degradation Products"/>
            </code>
            <subject>
              <!-- Medication/medication-batch-information-drug-pq-ex1 -->
              <reference value="Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"/>
            </subject>
            <effectiveDateTime value="2023-01-01T12:00:00Z"/>
            <performer>
              <!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
              <reference
                         value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
            </performer>
            <valueQuantity>
              <value value="0.2"/>
              <unit value="% w/w"/>
              <system value="http://unitsofmeasure.org"/>
              <code value="%"/>
            </valueQuantity>
            <component>
              <code>
                <coding>
                  <system
                          value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                  <code value="IMP"/>
                  <display value="Impurity"/>
                </coding>
              </code>
              <valueCodeableConcept>
                <!--  could have the code of an impurity substance, or could have an extension to point to it as a resource  -->
                <text value="Impurity 2"/>
              </valueCodeableConcept>
            </component>
          </Observation>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:332b1e76-6f70-2b4e-5d0c-f22a0e042d3e"/>
        <resource>
          <Observation>
            <!-- observationDegradation-imp2-2 -->
            <id value="332b1e76-6f70-2b4e-5d0c-f22a0e042d3e"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_332b1e76-6f70-2b4e-5d0c-f22a0e042d3e"> </a><p><b>Generated Narrative: Observation</b><a name="332b1e76-6f70-2b4e-5d0c-f22a0e042d3e"> </a><a name="hc332b1e76-6f70-2b4e-5d0c-f22a0e042d3e"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation &quot;332b1e76-6f70-2b4e-5d0c-f22a0e042d3e&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.2 % w/w<span style="background: LightGoldenRodYellow"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Impurity <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 2 <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></td></tr></table></div>
            </text>
            <instantiatesReference>
              <!-- ObservationDefinition/Degradation -->
              <reference
                         value="ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf"/>
            </instantiatesReference>
            <status value="final"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="DGP"/>
                <display value="Degradation Products"/>
              </coding>
              <text value="Degradation Products"/>
            </code>
            <subject>
              <!-- Medication/medication-actual-batch-2 -->
              <reference value="Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"/>
            </subject>
            <effectiveDateTime value="2023-01-01T12:00:00Z"/>
            <performer>
              <!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
              <reference
                         value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
            </performer>
            <valueQuantity>
              <value value="0.2"/>
              <unit value="% w/w"/>
              <system value="http://unitsofmeasure.org"/>
              <code value="%"/>
            </valueQuantity>
            <component>
              <code>
                <coding>
                  <system
                          value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                  <code value="IMP"/>
                  <display value="Impurity"/>
                </coding>
              </code>
              <valueCodeableConcept>
                <!--  could have the code of an impurity substance, or could have an extension to point to it as a resource  -->
                <text value="Impurity 2"/>
              </valueCodeableConcept>
            </component>
          </Observation>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:f0a13a3b-2e8b-594f-6874-6050511e4c57"/>
        <resource>
          <Observation>
            <!-- observationDegradation-imp2-3 -->
            <id value="f0a13a3b-2e8b-594f-6874-6050511e4c57"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_f0a13a3b-2e8b-594f-6874-6050511e4c57"> </a><p><b>Generated Narrative: Observation</b><a name="f0a13a3b-2e8b-594f-6874-6050511e4c57"> </a><a name="hcf0a13a3b-2e8b-594f-6874-6050511e4c57"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation &quot;f0a13a3b-2e8b-594f-6874-6050511e4c57&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.2 % w/w<span style="background: LightGoldenRodYellow"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Impurity <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 2 <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></td></tr></table></div>
            </text>
            <instantiatesReference>
              <!-- ObservationDefinition/Degradation -->
              <reference
                         value="ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf"/>
            </instantiatesReference>
            <status value="final"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="DGP"/>
                <display value="Degradation Products"/>
              </coding>
              <text value="Degradation Products"/>
            </code>
            <subject>
              <!-- Medication/medication-actual-batch-3 -->
              <reference value="Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"/>
            </subject>
            <effectiveDateTime value="2023-01-01T12:00:00Z"/>
            <performer>
              <!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
              <reference
                         value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
            </performer>
            <valueQuantity>
              <value value="0.2"/>
              <unit value="% w/w"/>
              <system value="http://unitsofmeasure.org"/>
              <code value="%"/>
            </valueQuantity>
            <component>
              <code>
                <coding>
                  <system
                          value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                  <code value="IMP"/>
                  <display value="Impurity"/>
                </coding>
              </code>
              <valueCodeableConcept>
                <!--  could have the code of an impurity substance, or could have an extension to point to it as a resource  -->
                <text value="Impurity 2"/>
              </valueCodeableConcept>
            </component>
          </Observation>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:7fe7ccd7-6449-0186-2282-3eeb4cf6a795"/>
        <resource>
          <Observation>
            <!-- observationDegradation-imp3 -->
            <id value="7fe7ccd7-6449-0186-2282-3eeb4cf6a795"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_7fe7ccd7-6449-0186-2282-3eeb4cf6a795"> </a><p><b>Generated Narrative: Observation</b><a name="7fe7ccd7-6449-0186-2282-3eeb4cf6a795"> </a><a name="hc7fe7ccd7-6449-0186-2282-3eeb4cf6a795"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation &quot;7fe7ccd7-6449-0186-2282-3eeb4cf6a795&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.2 % w/w<span style="background: LightGoldenRodYellow"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Impurity <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 3 <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></td></tr></table></div>
            </text>
            <instantiatesReference>
              <!-- ObservationDefinition/Degradation -->
              <reference
                         value="ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf"/>
            </instantiatesReference>
            <status value="final"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="DGP"/>
                <display value="Degradation Products"/>
              </coding>
              <text value="Degradation Products"/>
            </code>
            <subject>
              <!-- Medication/medication-batch-information-drug-pq-ex1 -->
              <reference value="Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"/>
            </subject>
            <effectiveDateTime value="2023-01-01T12:00:00Z"/>
            <performer>
              <!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
              <reference
                         value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
            </performer>
            <valueQuantity>
              <value value="0.2"/>
              <unit value="% w/w"/>
              <system value="http://unitsofmeasure.org"/>
              <code value="%"/>
            </valueQuantity>
            <component>
              <code>
                <coding>
                  <system
                          value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                  <code value="IMP"/>
                  <display value="Impurity"/>
                </coding>
              </code>
              <valueCodeableConcept>
                <!--  could have the code of an impurity substance, or could have an extension to point to it as a resource  -->
                <text value="Impurity 3"/>
              </valueCodeableConcept>
            </component>
          </Observation>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:be016630-8754-7414-9014-21e020ad66c6"/>
        <resource>
          <Observation>
            <!-- observationDegradation-imp3-2 -->
            <id value="be016630-8754-7414-9014-21e020ad66c6"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_be016630-8754-7414-9014-21e020ad66c6"> </a><p><b>Generated Narrative: Observation</b><a name="be016630-8754-7414-9014-21e020ad66c6"> </a><a name="hcbe016630-8754-7414-9014-21e020ad66c6"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation &quot;be016630-8754-7414-9014-21e020ad66c6&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.2 % w/w<span style="background: LightGoldenRodYellow"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Impurity <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 3 <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></td></tr></table></div>
            </text>
            <instantiatesReference>
              <!-- ObservationDefinition/Degradation -->
              <reference
                         value="ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf"/>
            </instantiatesReference>
            <status value="final"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="DGP"/>
                <display value="Degradation Products"/>
              </coding>
              <text value="Degradation Products"/>
            </code>
            <subject>
              <!-- Medication/medication-actual-batch-2 -->
              <reference value="Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"/>
            </subject>
            <effectiveDateTime value="2023-01-01T12:00:00Z"/>
            <performer>
              <!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
              <reference
                         value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
            </performer>
            <valueQuantity>
              <value value="0.2"/>
              <unit value="% w/w"/>
              <system value="http://unitsofmeasure.org"/>
              <code value="%"/>
            </valueQuantity>
            <component>
              <code>
                <coding>
                  <system
                          value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                  <code value="IMP"/>
                  <display value="Impurity"/>
                </coding>
              </code>
              <valueCodeableConcept>
                <!--  could have the code of an impurity substance, or could have an extension to point to it as a resource  -->
                <text value="Impurity 3"/>
              </valueCodeableConcept>
            </component>
          </Observation>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:92568f68-78f3-908c-6935-ff5f3d574dd6"/>
        <resource>
          <Observation>
            <!-- observationDegradation-imp3-3 -->
            <id value="92568f68-78f3-908c-6935-ff5f3d574dd6"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_92568f68-78f3-908c-6935-ff5f3d574dd6"> </a><p><b>Generated Narrative: Observation</b><a name="92568f68-78f3-908c-6935-ff5f3d574dd6"> </a><a name="hc92568f68-78f3-908c-6935-ff5f3d574dd6"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation &quot;92568f68-78f3-908c-6935-ff5f3d574dd6&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.2 % w/w<span style="background: LightGoldenRodYellow"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Impurity <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 3 <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></td></tr></table></div>
            </text>
            <instantiatesReference>
              <!-- ObservationDefinition/Degradation -->
              <reference
                         value="ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf"/>
            </instantiatesReference>
            <status value="final"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="DGP"/>
                <display value="Degradation Products"/>
              </coding>
              <text value="Degradation Products"/>
            </code>
            <subject>
              <!-- Medication/medication-actual-batch-3 -->
              <reference value="Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"/>
            </subject>
            <effectiveDateTime value="2023-01-01T12:00:00Z"/>
            <performer>
              <!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
              <reference
                         value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
            </performer>
            <valueQuantity>
              <value value="0.2"/>
              <unit value="% w/w"/>
              <system value="http://unitsofmeasure.org"/>
              <code value="%"/>
            </valueQuantity>
            <component>
              <code>
                <coding>
                  <system
                          value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                  <code value="IMP"/>
                  <display value="Impurity"/>
                </coding>
              </code>
              <valueCodeableConcept>
                <!--  could have the code of an impurity substance, or could have an extension to point to it as a resource  -->
                <text value="Impurity 3"/>
              </valueCodeableConcept>
            </component>
          </Observation>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:a0ba0f6d-8ec0-846a-a70d-f6bca6d01a12"/>
        <resource>
          <Observation>
            <!-- observationDegradation-imp-unspecified -->
            <id value="a0ba0f6d-8ec0-846a-a70d-f6bca6d01a12"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_a0ba0f6d-8ec0-846a-a70d-f6bca6d01a12"> </a><p><b>Generated Narrative: Observation</b><a name="a0ba0f6d-8ec0-846a-a70d-f6bca6d01a12"> </a><a name="hca0ba0f6d-8ec0-846a-a70d-f6bca6d01a12"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation &quot;a0ba0f6d-8ec0-846a-a70d-f6bca6d01a12&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.1 % w/w<span style="background: LightGoldenRodYellow"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Impurity <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#IMP)</span></td><td>Individual unspecified degradation products <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></td></tr></table></div>
            </text>
            <instantiatesReference>
              <!-- ObservationDefinition/Degradation -->
              <reference
                         value="ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf"/>
            </instantiatesReference>
            <status value="final"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="DGP"/>
                <display value="Degradation Products"/>
              </coding>
              <text value="Degradation Products"/>
            </code>
            <subject>
              <!-- Medication/medication-batch-information-drug-pq-ex1 -->
              <reference value="Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"/>
            </subject>
            <effectiveDateTime value="2023-01-01T12:00:00Z"/>
            <performer>
              <!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
              <reference
                         value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
            </performer>
            <valueQuantity>
              <value value="0.1"/>
              <unit value="% w/w"/>
              <system value="http://unitsofmeasure.org"/>
              <code value="%"/>
            </valueQuantity>
            <component>
              <code>
                <coding>
                  <system
                          value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                  <code value="IMP"/>
                  <display value="Impurity"/>
                </coding>
              </code>
              <valueCodeableConcept>
                <!--  could have the code of an impurity substance, or could have an extension to point to it as a resource  -->
                <text value="Individual unspecified degradation products"/>
              </valueCodeableConcept>
            </component>
          </Observation>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:d8533dcb-03f8-5997-6ccf-4f9b6f7a5745"/>
        <resource>
          <Observation>
            <!-- observationDegradation-imp-unspecified-2 -->
            <id value="d8533dcb-03f8-5997-6ccf-4f9b6f7a5745"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_d8533dcb-03f8-5997-6ccf-4f9b6f7a5745"> </a><p><b>Generated Narrative: Observation</b><a name="d8533dcb-03f8-5997-6ccf-4f9b6f7a5745"> </a><a name="hcd8533dcb-03f8-5997-6ccf-4f9b6f7a5745"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation &quot;d8533dcb-03f8-5997-6ccf-4f9b6f7a5745&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.1 % w/w<span style="background: LightGoldenRodYellow"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Impurity <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#IMP)</span></td><td>Individual unspecified degradation products <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></td></tr></table></div>
            </text>
            <instantiatesReference>
              <!-- ObservationDefinition/Degradation -->
              <reference
                         value="ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf"/>
            </instantiatesReference>
            <status value="final"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="DGP"/>
                <display value="Degradation Products"/>
              </coding>
              <text value="Degradation Products"/>
            </code>
            <subject>
              <!-- Medication/medication-actual-batch-2 -->
              <reference value="Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"/>
            </subject>
            <effectiveDateTime value="2023-01-01T12:00:00Z"/>
            <performer>
              <!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
              <reference
                         value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
            </performer>
            <valueQuantity>
              <value value="0.1"/>
              <unit value="% w/w"/>
              <system value="http://unitsofmeasure.org"/>
              <code value="%"/>
            </valueQuantity>
            <component>
              <code>
                <coding>
                  <system
                          value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                  <code value="IMP"/>
                  <display value="Impurity"/>
                </coding>
              </code>
              <valueCodeableConcept>
                <!--  could have the code of an impurity substance, or could have an extension to point to it as a resource  -->
                <text value="Individual unspecified degradation products"/>
              </valueCodeableConcept>
            </component>
          </Observation>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:7cec19a2-34a7-6b80-3d60-083b2cc64fcb"/>
        <resource>
          <Observation>
            <!-- observationDegradation-imp-unspecified-3 -->
            <id value="7cec19a2-34a7-6b80-3d60-083b2cc64fcb"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_7cec19a2-34a7-6b80-3d60-083b2cc64fcb"> </a><p><b>Generated Narrative: Observation</b><a name="7cec19a2-34a7-6b80-3d60-083b2cc64fcb"> </a><a name="hc7cec19a2-34a7-6b80-3d60-083b2cc64fcb"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation &quot;7cec19a2-34a7-6b80-3d60-083b2cc64fcb&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.1 % w/w<span style="background: LightGoldenRodYellow"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Impurity <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#IMP)</span></td><td>Individual unspecified degradation products <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></td></tr></table></div>
            </text>
            <instantiatesReference>
              <!-- ObservationDefinition/Degradation -->
              <reference
                         value="ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf"/>
            </instantiatesReference>
            <status value="final"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="DGP"/>
                <display value="Degradation Products"/>
              </coding>
              <text value="Degradation Products"/>
            </code>
            <subject>
              <!-- Medication/medication-actual-batch-3 -->
              <reference value="Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"/>
            </subject>
            <effectiveDateTime value="2023-01-01T12:00:00Z"/>
            <performer>
              <!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
              <reference
                         value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
            </performer>
            <valueQuantity>
              <value value="0.1"/>
              <unit value="% w/w"/>
              <system value="http://unitsofmeasure.org"/>
              <code value="%"/>
            </valueQuantity>
            <component>
              <code>
                <coding>
                  <system
                          value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                  <code value="IMP"/>
                  <display value="Impurity"/>
                </coding>
              </code>
              <valueCodeableConcept>
                <!--  could have the code of an impurity substance, or could have an extension to point to it as a resource  -->
                <text value="Individual unspecified degradation products"/>
              </valueCodeableConcept>
            </component>
          </Observation>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:27aa47fd-7964-4f96-6495-b2bec7f160e7"/>
        <resource>
          <Observation>
            <!-- observationDegradation-imp-total -->
            <id value="27aa47fd-7964-4f96-6495-b2bec7f160e7"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_27aa47fd-7964-4f96-6495-b2bec7f160e7"> </a><p><b>Generated Narrative: Observation</b><a name="27aa47fd-7964-4f96-6495-b2bec7f160e7"> </a><a name="hc27aa47fd-7964-4f96-6495-b2bec7f160e7"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation &quot;27aa47fd-7964-4f96-6495-b2bec7f160e7&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.6 % w/w<span style="background: LightGoldenRodYellow"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Impurity <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#IMP)</span></td><td>Total degradation products <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></td></tr></table></div>
            </text>
            <instantiatesReference>
              <!-- ObservationDefinition/Degradation -->
              <reference
                         value="ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf"/>
            </instantiatesReference>
            <status value="final"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="DGP"/>
                <display value="Degradation Products"/>
              </coding>
              <text value="Degradation Products"/>
            </code>
            <subject>
              <!-- Medication/medication-batch-information-drug-pq-ex1 -->
              <reference value="Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"/>
            </subject>
            <effectiveDateTime value="2023-01-01T12:00:00Z"/>
            <performer>
              <!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
              <reference
                         value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
            </performer>
            <valueQuantity>
              <value value="0.6"/>
              <unit value="% w/w"/>
              <system value="http://unitsofmeasure.org"/>
              <code value="%"/>
            </valueQuantity>
            <component>
              <code>
                <coding>
                  <system
                          value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                  <code value="IMP"/>
                  <display value="Impurity"/>
                </coding>
              </code>
              <valueCodeableConcept>
                <!--  could have the code of an impurity substance, or could have an extension to point to it as a resource  -->
                <text value="Total degradation products"/>
              </valueCodeableConcept>
            </component>
          </Observation>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:6a78bcde-4781-226c-946e-a4b6915c1899"/>
        <resource>
          <Observation>
            <!-- observationDegradation-imp-total-2 -->
            <id value="6a78bcde-4781-226c-946e-a4b6915c1899"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_6a78bcde-4781-226c-946e-a4b6915c1899"> </a><p><b>Generated Narrative: Observation</b><a name="6a78bcde-4781-226c-946e-a4b6915c1899"> </a><a name="hc6a78bcde-4781-226c-946e-a4b6915c1899"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation &quot;6a78bcde-4781-226c-946e-a4b6915c1899&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.7 % w/w<span style="background: LightGoldenRodYellow"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Impurity <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#IMP)</span></td><td>Total degradation products <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></td></tr></table></div>
            </text>
            <instantiatesReference>
              <!-- ObservationDefinition/Degradation -->
              <reference
                         value="ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf"/>
            </instantiatesReference>
            <status value="final"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="DGP"/>
                <display value="Degradation Products"/>
              </coding>
              <text value="Degradation Products"/>
            </code>
            <subject>
              <!-- Medication/medication-actual-batch-2 -->
              <reference value="Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"/>
            </subject>
            <effectiveDateTime value="2023-01-01T12:00:00Z"/>
            <performer>
              <!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
              <reference
                         value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
            </performer>
            <valueQuantity>
              <value value="0.7"/>
              <unit value="% w/w"/>
              <system value="http://unitsofmeasure.org"/>
              <code value="%"/>
            </valueQuantity>
            <component>
              <code>
                <coding>
                  <system
                          value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                  <code value="IMP"/>
                  <display value="Impurity"/>
                </coding>
              </code>
              <valueCodeableConcept>
                <!--  could have the code of an impurity substance, or could have an extension to point to it as a resource  -->
                <text value="Total degradation products"/>
              </valueCodeableConcept>
            </component>
          </Observation>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:f9f11088-7527-947c-3d3f-e71b32e13c78"/>
        <resource>
          <Observation>
            <!-- observationDegradation-imp-total-3 -->
            <id value="f9f11088-7527-947c-3d3f-e71b32e13c78"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_f9f11088-7527-947c-3d3f-e71b32e13c78"> </a><p><b>Generated Narrative: Observation</b><a name="f9f11088-7527-947c-3d3f-e71b32e13c78"> </a><a name="hcf9f11088-7527-947c-3d3f-e71b32e13c78"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation &quot;f9f11088-7527-947c-3d3f-e71b32e13c78&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.6 % w/w<span style="background: LightGoldenRodYellow"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Impurity <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#IMP)</span></td><td>Total degradation products <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></td></tr></table></div>
            </text>
            <instantiatesReference>
              <!-- ObservationDefinition/Degradation -->
              <reference
                         value="ObservationDefinition/8bdea820-4197-7c7d-0990-7be06bf78aaf"/>
            </instantiatesReference>
            <status value="final"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="DGP"/>
                <display value="Degradation Products"/>
              </coding>
              <text value="Degradation Products"/>
            </code>
            <subject>
              <!-- Medication/medication-actual-batch-3 -->
              <reference value="Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"/>
            </subject>
            <effectiveDateTime value="2023-01-01T12:00:00Z"/>
            <performer>
              <!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
              <reference
                         value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
            </performer>
            <valueQuantity>
              <value value="0.6"/>
              <unit value="% w/w"/>
              <system value="http://unitsofmeasure.org"/>
              <code value="%"/>
            </valueQuantity>
            <component>
              <code>
                <coding>
                  <system
                          value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                  <code value="IMP"/>
                  <display value="Impurity"/>
                </coding>
              </code>
              <valueCodeableConcept>
                <!--  could have the code of an impurity substance, or could have an extension to point to it as a resource  -->
                <text value="Total degradation products"/>
              </valueCodeableConcept>
            </component>
          </Observation>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:66c2f585-678e-78b8-2235-1a3b37bd6e46"/>
        <resource>
          <Observation>
            <!-- observationWater -->
            <id value="66c2f585-678e-78b8-2235-1a3b37bd6e46"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_66c2f585-678e-78b8-2235-1a3b37bd6e46"> </a><p><b>Generated Narrative: Observation</b><a name="66c2f585-678e-78b8-2235-1a3b37bd6e46"> </a><a name="hc66c2f585-678e-78b8-2235-1a3b37bd6e46"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation &quot;66c2f585-678e-78b8-2235-1a3b37bd6e46&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/31e29d22-5fcb-546e-24fd-52a4a4004467</p><p><b>status</b>: final</p><p><b>code</b>: Water Content <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#WaterContent)</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.5 % w/w<span style="background: LightGoldenRodYellow"> (Details: UCUM code % = '%')</span></p></div>
            </text>
            <instantiatesReference>
              <!-- ObservationDefinition/Water -->
              <reference
                         value="ObservationDefinition/31e29d22-5fcb-546e-24fd-52a4a4004467"/>
            </instantiatesReference>
            <status value="final"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="WaterContent"/>
                <display value="Water Content"/>
              </coding>
              <text value="Water Content"/>
            </code>
            <subject>
              <!-- Medication/medication-batch-information-drug-pq-ex1 -->
              <reference value="Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"/>
            </subject>
            <effectiveDateTime value="2023-01-01T12:00:00Z"/>
            <performer>
              <!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
              <reference
                         value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
            </performer>
            <valueQuantity>
              <value value="0.5"/>
              <unit value="% w/w"/>
              <system value="http://unitsofmeasure.org"/>
              <code value="%"/>
            </valueQuantity>
          </Observation>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:f8232d25-023d-679f-9c58-a6dc234b7a28"/>
        <resource>
          <Observation>
            <!-- observationWater2 -->
            <id value="f8232d25-023d-679f-9c58-a6dc234b7a28"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_f8232d25-023d-679f-9c58-a6dc234b7a28"> </a><p><b>Generated Narrative: Observation</b><a name="f8232d25-023d-679f-9c58-a6dc234b7a28"> </a><a name="hcf8232d25-023d-679f-9c58-a6dc234b7a28"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation &quot;f8232d25-023d-679f-9c58-a6dc234b7a28&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/31e29d22-5fcb-546e-24fd-52a4a4004467</p><p><b>status</b>: final</p><p><b>code</b>: Water Content <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#WaterContent)</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.5 % w/w<span style="background: LightGoldenRodYellow"> (Details: UCUM code % = '%')</span></p></div>
            </text>
            <instantiatesReference>
              <!-- ObservationDefinition/Water -->
              <reference
                         value="ObservationDefinition/31e29d22-5fcb-546e-24fd-52a4a4004467"/>
            </instantiatesReference>
            <status value="final"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="WaterContent"/>
                <display value="Water Content"/>
              </coding>
              <text value="Water Content"/>
            </code>
            <subject>
              <!-- Medication/medication-actual-batch-2 -->
              <reference value="Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"/>
            </subject>
            <effectiveDateTime value="2023-01-01T12:00:00Z"/>
            <performer>
              <!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
              <reference
                         value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
            </performer>
            <valueQuantity>
              <value value="0.5"/>
              <unit value="% w/w"/>
              <system value="http://unitsofmeasure.org"/>
              <code value="%"/>
            </valueQuantity>
          </Observation>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:368b82be-75dd-1d97-3dbc-a7eed9869daa"/>
        <resource>
          <Observation>
            <!-- observationWater3 -->
            <id value="368b82be-75dd-1d97-3dbc-a7eed9869daa"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_368b82be-75dd-1d97-3dbc-a7eed9869daa"> </a><p><b>Generated Narrative: Observation</b><a name="368b82be-75dd-1d97-3dbc-a7eed9869daa"> </a><a name="hc368b82be-75dd-1d97-3dbc-a7eed9869daa"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation &quot;368b82be-75dd-1d97-3dbc-a7eed9869daa&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/31e29d22-5fcb-546e-24fd-52a4a4004467</p><p><b>status</b>: final</p><p><b>code</b>: Water Content <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#WaterContent)</span></p><p><b>subject</b>: See on this page: Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.5 % w/w<span style="background: LightGoldenRodYellow"> (Details: UCUM code % = '%')</span></p></div>
            </text>
            <instantiatesReference>
              <!-- ObservationDefinition/Water -->
              <reference
                         value="ObservationDefinition/31e29d22-5fcb-546e-24fd-52a4a4004467"/>
            </instantiatesReference>
            <status value="final"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="WaterContent"/>
                <display value="Water Content"/>
              </coding>
              <text value="Water Content"/>
            </code>
            <subject>
              <!-- Medication/medication-actual-batch-3 -->
              <reference value="Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"/>
            </subject>
            <effectiveDateTime value="2023-01-01T12:00:00Z"/>
            <performer>
              <!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
              <reference
                         value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
            </performer>
            <valueQuantity>
              <value value="0.5"/>
              <unit value="% w/w"/>
              <system value="http://unitsofmeasure.org"/>
              <code value="%"/>
            </valueQuantity>
          </Observation>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:44aa47fd-8964-4f96-6495-b2bec7f160e7"/>
        <resource>
          <Observation>
            <!-- fillingTAMC1 -->
            <id value="44aa47fd-8964-4f96-6495-b2bec7f160e7"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_44aa47fd-8964-4f96-6495-b2bec7f160e7"> </a><p><b>Generated Narrative: Observation</b><a name="44aa47fd-8964-4f96-6495-b2bec7f160e7"> </a><a name="hc44aa47fd-8964-4f96-6495-b2bec7f160e7"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation &quot;44aa47fd-8964-4f96-6495-b2bec7f160e7&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/64505a3c-5034-448a-9c19-938ce1958424</p><p><b>status</b>: final</p><p><b>code</b>: TAMC <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#TAMC)</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 9.1 CFU/100ml</p></div>
            </text>
            <instantiatesReference>
              <!-- ObservationDefinition/TAMC -->
              <reference
                         value="ObservationDefinition/64505a3c-5034-448a-9c19-938ce1958424"/>
            </instantiatesReference>
            <status value="final"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="TAMC"/>
                <display value="TAMC"/>
              </coding>
              <text value="TAMC"/>
            </code>
            <subject>
              <!-- Medication/medication-batch-information-drug-pq-ex1 -->
              <reference value="Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"/>
            </subject>
            <effectiveDateTime value="2023-01-01T12:00:00Z"/>
            <performer>
              <!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
              <reference
                         value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
            </performer>
            <!--  todo UCUM  -->
            <valueQuantity>
              <value value="9.1"/>
              <unit value="CFU/100ml"/>
            </valueQuantity>
          </Observation>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:45aa47fd-8964-4f96-6495-b2bec7f160e7"/>
        <resource>
          <Observation>
            <!-- fillingConclusion-nosubject -->
            <id value="45aa47fd-8964-4f96-6495-b2bec7f160e7"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_45aa47fd-8964-4f96-6495-b2bec7f160e7"> </a><p><b>Generated Narrative: Observation</b><a name="45aa47fd-8964-4f96-6495-b2bec7f160e7"> </a><a name="hc45aa47fd-8964-4f96-6495-b2bec7f160e7"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation &quot;45aa47fd-8964-4f96-6495-b2bec7f160e7&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/22515a3c-5034-448a-9c19-938ce1958424</p><p><b>status</b>: final</p><p><b>code</b>: Conclusion <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#CONC)</span></p><p><b>subject</b>: <span>: all batches</span></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: Conclusion of filling tests....</p></div>
            </text>
            <instantiatesReference>
              <!-- ObservationDefinition/conclusion -->
              <reference
                         value="ObservationDefinition/22515a3c-5034-448a-9c19-938ce1958424"/>
            </instantiatesReference>
            <status value="final"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="CONC"/>
                <display value="Conclusion"/>
              </coding>
              <text value="Conclusion"/>
            </code>
            <!--  no subject because it applies to all the samples  -->
            <subject>
              <extension
                         url="http://hl7.org/fhir/StructureDefinition/data-absent-reason">
                <valueCode value="unsupported"/>
              </extension>
              <display value="all batches"/>
            </subject>
            <effectiveDateTime value="2023-01-01T12:00:00Z"/>
            <performer>
              <!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
              <reference
                         value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
            </performer>
            <valueString value="Conclusion of filling tests...."/>
          </Observation>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:45ab47fd-8964-4f96-6495-b2bec7f160e7"/>
        <resource>
          <Observation>
            <!--  no subject  -->
            <!-- lyophilizationConclusion-nosubject -->
            <id value="45ab47fd-8964-4f96-6495-b2bec7f160e7"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_45ab47fd-8964-4f96-6495-b2bec7f160e7"> </a><p><b>Generated Narrative: Observation</b><a name="45ab47fd-8964-4f96-6495-b2bec7f160e7"> </a><a name="hc45ab47fd-8964-4f96-6495-b2bec7f160e7"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation &quot;45ab47fd-8964-4f96-6495-b2bec7f160e7&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/22525a3c-5034-448a-9c19-938ce1958424</p><p><b>status</b>: final</p><p><b>code</b>: Conclusion <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#CONC)</span></p><p><b>subject</b>: <span>: all batches</span></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: Conclusion of lyophilization tests....</p></div>
            </text>
            <instantiatesReference>
              <!-- ObservationDefinition/LyophilizationConclusion -->
              <reference
                         value="ObservationDefinition/22525a3c-5034-448a-9c19-938ce1958424"/>
            </instantiatesReference>
            <status value="final"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="CONC"/>
                <display value="Conclusion"/>
              </coding>
              <text value="Conclusion"/>
            </code>
            <!--  no subject because it applies to all the samples  -->
            <subject>
              <extension
                         url="http://hl7.org/fhir/StructureDefinition/data-absent-reason">
                <valueCode value="unsupported"/>
              </extension>
              <display value="all batches"/>
            </subject>
            <effectiveDateTime value="2023-01-01T12:00:00Z"/>
            <performer>
              <!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
              <reference
                         value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
            </performer>
            <valueString value="Conclusion of lyophilization tests...."/>
          </Observation>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:37aa47fd-8964-4f96-6495-b2bec7f160e7"/>
        <resource>
          <Observation>
            <!-- lyophilizerNumber1 -->
            <id value="37aa47fd-8964-4f96-6495-b2bec7f160e7"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_37aa47fd-8964-4f96-6495-b2bec7f160e7"> </a><p><b>Generated Narrative: Observation</b><a name="37aa47fd-8964-4f96-6495-b2bec7f160e7"> </a><a name="hc37aa47fd-8964-4f96-6495-b2bec7f160e7"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation &quot;37aa47fd-8964-4f96-6495-b2bec7f160e7&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/64535a3c-5334-448a-9c29-938ce2958424</p><p><b>status</b>: final</p><p><b>code</b>: Assay <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#Lyophilizer Number &quot;Lyophilizer Number&quot;)</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 1234</p></div>
            </text>
            <instantiatesReference>
              <!-- ObservationDefinition/LyophilizerNumber -->
              <reference
                         value="ObservationDefinition/64535a3c-5334-448a-9c29-938ce2958424"/>
            </instantiatesReference>
            <status value="final"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="Lyophilizer Number"/>
                <display value="Lyophilizer Number"/>
              </coding>
              <text value="Assay"/>
            </code>
            <subject>
              <!-- Medication/medication-batch-information-drug-pq-ex1 -->
              <reference value="Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"/>
            </subject>
            <effectiveDateTime value="2023-01-01T12:00:00Z"/>
            <performer>
              <!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
              <reference
                         value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
            </performer>
            <valueQuantity>
              <value value="1234"/>
            </valueQuantity>
          </Observation>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:38aa47fd-8964-4f96-6495-b2bec7f160e7"/>
        <resource>
          <Observation>
            <!-- lyophilizerNumber2 -->
            <id value="38aa47fd-8964-4f96-6495-b2bec7f160e7"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_38aa47fd-8964-4f96-6495-b2bec7f160e7"> </a><p><b>Generated Narrative: Observation</b><a name="38aa47fd-8964-4f96-6495-b2bec7f160e7"> </a><a name="hc38aa47fd-8964-4f96-6495-b2bec7f160e7"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation &quot;38aa47fd-8964-4f96-6495-b2bec7f160e7&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/64535a3c-5334-448a-9c29-938ce2958424</p><p><b>status</b>: final</p><p><b>code</b>: Assay <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#Lyophilizer Number &quot;Lyophilizer Number&quot;)</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 1235</p></div>
            </text>
            <instantiatesReference>
              <!-- ObservationDefinition/LyophilizerNumber -->
              <reference
                         value="ObservationDefinition/64535a3c-5334-448a-9c29-938ce2958424"/>
            </instantiatesReference>
            <status value="final"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="Lyophilizer Number"/>
                <display value="Lyophilizer Number"/>
              </coding>
              <text value="Assay"/>
            </code>
            <subject>
              <!-- Medication/medication-actual-batch-2 -->
              <reference value="Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"/>
            </subject>
            <effectiveDateTime value="2023-01-01T12:00:00Z"/>
            <performer>
              <!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
              <reference
                         value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
            </performer>
            <valueQuantity>
              <value value="1235"/>
            </valueQuantity>
          </Observation>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:38aa48fd-8964-4f96-6495-b2bec7f160e7"/>
        <resource>
          <Observation>
            <!-- lyophilizerNumber3 -->
            <id value="38aa48fd-8964-4f96-6495-b2bec7f160e7"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_38aa48fd-8964-4f96-6495-b2bec7f160e7"> </a><p><b>Generated Narrative: Observation</b><a name="38aa48fd-8964-4f96-6495-b2bec7f160e7"> </a><a name="hc38aa48fd-8964-4f96-6495-b2bec7f160e7"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation &quot;38aa48fd-8964-4f96-6495-b2bec7f160e7&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/64535a3c-5334-448a-9c29-938ce2958424</p><p><b>status</b>: final</p><p><b>code</b>: Assay <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#Lyophilizer Number &quot;Lyophilizer Number&quot;)</span></p><p><b>subject</b>: See on this page: Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 1236</p></div>
            </text>
            <instantiatesReference>
              <!-- ObservationDefinition/LyophilizerNumber -->
              <reference
                         value="ObservationDefinition/64535a3c-5334-448a-9c29-938ce2958424"/>
            </instantiatesReference>
            <status value="final"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="Lyophilizer Number"/>
                <display value="Lyophilizer Number"/>
              </coding>
              <text value="Assay"/>
            </code>
            <subject>
              <!-- Medication/medication-actual-batch-3 -->
              <reference value="Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"/>
            </subject>
            <effectiveDateTime value="2023-01-01T12:00:00Z"/>
            <performer>
              <!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
              <reference
                         value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
            </performer>
            <valueQuantity>
              <value value="1236"/>
            </valueQuantity>
          </Observation>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:37aa47fd-7964-4f96-6495-b2bec7f160e7"/>
        <resource>
          <Observation>
            <!-- lyophilizationAssay1 -->
            <id value="37aa47fd-7964-4f96-6495-b2bec7f160e7"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_37aa47fd-7964-4f96-6495-b2bec7f160e7"> </a><p><b>Generated Narrative: Observation</b><a name="37aa47fd-7964-4f96-6495-b2bec7f160e7"> </a><a name="hc37aa47fd-7964-4f96-6495-b2bec7f160e7"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation &quot;37aa47fd-7964-4f96-6495-b2bec7f160e7&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/22e7e672-40a6-4036-3c1f-b8ba6a7d045e</p><p><b>status</b>: final</p><p><b>code</b>: Assay <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#ASSAY)</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 97 %<span style="background: LightGoldenRodYellow"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Number of Locations <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#LOC)</span></td><td>3</td></tr></table></div>
            </text>
            <instantiatesReference>
              <!-- ObservationDefinition/LyophilizationAssay -->
              <reference
                         value="ObservationDefinition/22e7e672-40a6-4036-3c1f-b8ba6a7d045e"/>
            </instantiatesReference>
            <status value="final"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="ASSAY"/>
                <display value="Assay"/>
              </coding>
              <text value="Assay"/>
            </code>
            <subject>
              <!-- Medication/medication-batch-information-drug-pq-ex1 -->
              <reference value="Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"/>
            </subject>
            <effectiveDateTime value="2023-01-01T12:00:00Z"/>
            <performer>
              <!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
              <reference
                         value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
            </performer>
            <valueQuantity>
              <value value="97"/>
              <unit value="%"/>
              <system value="http://unitsofmeasure.org"/>
              <code value="%"/>
            </valueQuantity>
            <component>
              <code>
                <coding>
                  <system
                          value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                  <code value="LOC"/>
                  <display value="Number of Locations"/>
                </coding>
              </code>
              <valueInteger value="3"/>
            </component>
          </Observation>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:47aa47fd-7964-4f96-6495-b2bec7f160e7"/>
        <resource>
          <Observation>
            <!-- lyophilizationAssay2 -->
            <id value="47aa47fd-7964-4f96-6495-b2bec7f160e7"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_47aa47fd-7964-4f96-6495-b2bec7f160e7"> </a><p><b>Generated Narrative: Observation</b><a name="47aa47fd-7964-4f96-6495-b2bec7f160e7"> </a><a name="hc47aa47fd-7964-4f96-6495-b2bec7f160e7"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation &quot;47aa47fd-7964-4f96-6495-b2bec7f160e7&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/22e7e672-40a6-4036-3c1f-b8ba6a7d045e</p><p><b>status</b>: final</p><p><b>code</b>: Assay <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#ASSAY)</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 98 %<span style="background: LightGoldenRodYellow"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Number of Locations <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#LOC)</span></td><td>4</td></tr></table></div>
            </text>
            <instantiatesReference>
              <!-- ObservationDefinition/LyophilizationAssay -->
              <reference
                         value="ObservationDefinition/22e7e672-40a6-4036-3c1f-b8ba6a7d045e"/>
            </instantiatesReference>
            <status value="final"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="ASSAY"/>
                <display value="Assay"/>
              </coding>
              <text value="Assay"/>
            </code>
            <subject>
              <!-- Medication/medication-actual-batch-2 -->
              <reference value="Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"/>
            </subject>
            <effectiveDateTime value="2023-01-01T12:00:00Z"/>
            <performer>
              <!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
              <reference
                         value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
            </performer>
            <valueQuantity>
              <value value="98"/>
              <unit value="%"/>
              <system value="http://unitsofmeasure.org"/>
              <code value="%"/>
            </valueQuantity>
            <component>
              <code>
                <coding>
                  <system
                          value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                  <code value="LOC"/>
                  <display value="Number of Locations"/>
                </coding>
              </code>
              <valueInteger value="4"/>
            </component>
          </Observation>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:47aa47fd-7964-4f96-6495-b2bec7f160e8"/>
        <resource>
          <Observation>
            <!-- lyophilizationAssay3 -->
            <id value="47aa47fd-7964-4f96-6495-b2bec7f160e8"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_47aa47fd-7964-4f96-6495-b2bec7f160e8"> </a><p><b>Generated Narrative: Observation</b><a name="47aa47fd-7964-4f96-6495-b2bec7f160e8"> </a><a name="hc47aa47fd-7964-4f96-6495-b2bec7f160e8"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation &quot;47aa47fd-7964-4f96-6495-b2bec7f160e8&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/22e7e672-40a6-4036-3c1f-b8ba6a7d045e</p><p><b>status</b>: final</p><p><b>code</b>: Assay <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#ASSAY)</span></p><p><b>subject</b>: See on this page: Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 96 %<span style="background: LightGoldenRodYellow"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Number of Locations <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#LOC)</span></td><td>2</td></tr></table></div>
            </text>
            <instantiatesReference>
              <!-- ObservationDefinition/LyophilizationAssay -->
              <reference
                         value="ObservationDefinition/22e7e672-40a6-4036-3c1f-b8ba6a7d045e"/>
            </instantiatesReference>
            <status value="final"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="ASSAY"/>
                <display value="Assay"/>
              </coding>
              <text value="Assay"/>
            </code>
            <subject>
              <!-- Medication/medication-actual-batch-3 -->
              <reference value="Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"/>
            </subject>
            <effectiveDateTime value="2023-01-01T12:00:00Z"/>
            <performer>
              <!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
              <reference
                         value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
            </performer>
            <valueQuantity>
              <value value="96"/>
              <unit value="%"/>
              <system value="http://unitsofmeasure.org"/>
              <code value="%"/>
            </valueQuantity>
            <component>
              <code>
                <coding>
                  <system
                          value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                  <code value="LOC"/>
                  <display value="Number of Locations"/>
                </coding>
              </code>
              <valueInteger value="2"/>
            </component>
          </Observation>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:47aa47fd-8964-4f96-6495-b2bec7f160e7"/>
        <resource>
          <Observation>
            <!-- lyophilizerWaterHomogeneity1 -->
            <id value="47aa47fd-8964-4f96-6495-b2bec7f160e7"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_47aa47fd-8964-4f96-6495-b2bec7f160e7"> </a><p><b>Generated Narrative: Observation</b><a name="47aa47fd-8964-4f96-6495-b2bec7f160e7"> </a><a name="hc47aa47fd-8964-4f96-6495-b2bec7f160e7"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation &quot;47aa47fd-8964-4f96-6495-b2bec7f160e7&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/32e29d22-6fcb-546e-24fd-52a4a4004467</p><p><b>status</b>: final</p><p><b>code</b>: Lyophilization Water Homogeneity <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#Lyophilization Water Homogeneity)</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><blockquote><p><b>component</b></p><p><b>code</b>: Do statistically significant effects <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#SSE &quot;Statistically significant effects&quot;)</span></p><p><b>value</b>: Yes</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Lower one-sided 95% confidence limit of Max Difference <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#LCL)</span></p><p><b>value</b>: 0.8 %</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Upper one-sided 95% confidence limit of Max Difference <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#UCL)</span></p><p><b>value</b>: 0.9 %</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Was Homogeneity demonstrated? <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#Homogeneity &quot;Homogeneity demonstrated&quot;)</span></p><p><b>value</b>: Yes</p></blockquote></div>
            </text>
            <instantiatesReference>
              <!-- ObservationDefinition/LyophilizationWaterHomogeneity -->
              <reference
                         value="ObservationDefinition/32e29d22-6fcb-546e-24fd-52a4a4004467"/>
            </instantiatesReference>
            <status value="final"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="Lyophilization Water Homogeneity"/>
                <display value="Lyophilization Water Homogeneity"/>
              </coding>
              <text value="Lyophilization Water Homogeneity"/>
            </code>
            <subject>
              <!-- Medication/medication-batch-information-drug-pq-ex1 -->
              <reference value="Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"/>
            </subject>
            <effectiveDateTime value="2023-01-01T12:00:00Z"/>
            <performer>
              <!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
              <reference
                         value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
            </performer>
            <component>
              <code>
                <coding>
                  <system
                          value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                  <code value="SSE"/>
                  <display value="Statistically significant effects"/>
                </coding>
                <text value="Do statistically significant effects"/>
              </code>
              <valueString value="Yes"/>
            </component>
            <component>
              <code>
                <coding>
                  <system
                          value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                  <code value="LCL"/>
                  <display
                           value="Lower one-sided 95% confidence limit of Max Difference"/>
                </coding>
              </code>
              <valueQuantity>
                <value value="0.8"/>
                <unit value="%"/>
              </valueQuantity>
            </component>
            <component>
              <code>
                <coding>
                  <system
                          value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                  <code value="UCL"/>
                  <display
                           value="Upper one-sided 95% confidence limit of Max Difference"/>
                </coding>
                <text
                      value="Upper one-sided 95% confidence limit of Max Difference"/>
              </code>
              <valueQuantity>
                <value value="0.9"/>
                <unit value="%"/>
              </valueQuantity>
            </component>
            <!--  boolean?  -->
            <component>
              <code>
                <coding>
                  <system
                          value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                  <code value="Homogeneity"/>
                  <display value="Homogeneity demonstrated"/>
                </coding>
                <text value="Was Homogeneity demonstrated?"/>
              </code>
              <valueString value="Yes"/>
            </component>
          </Observation>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:47aa47fd-8964-5f96-6495-b2bec7f160e7"/>
        <resource>
          <Observation>
            <!-- lyophilizerAssayHomogeneity1 -->
            <id value="47aa47fd-8964-5f96-6495-b2bec7f160e7"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_47aa47fd-8964-5f96-6495-b2bec7f160e7"> </a><p><b>Generated Narrative: Observation</b><a name="47aa47fd-8964-5f96-6495-b2bec7f160e7"> </a><a name="hc47aa47fd-8964-5f96-6495-b2bec7f160e7"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation &quot;47aa47fd-8964-5f96-6495-b2bec7f160e7&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/32e29d32-6fcb-546e-24fd-52a4a4004467</p><p><b>status</b>: final</p><p><b>code</b>: Lyophilization Assay Homogeneity <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#Lyophilization Assay Homogeneity)</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><blockquote><p><b>component</b></p><p><b>code</b>: Do statistically significant effects <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#SSE &quot;Statistically significant effects&quot;)</span></p><p><b>value</b>: No</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Lower one-sided 95% confidence limit of Max Difference <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#LCL)</span></p><p><b>value</b>: Not calculated</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Upper one-sided 95% confidence limit of Max Difference <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#UCL)</span></p><p><b>value</b>: Not calculated</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Was Homogeneity demonstrated? <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#Homogeneity &quot;Homogeneity demonstrated&quot;)</span></p><p><b>value</b>: Yes</p></blockquote></div>
            </text>
            <instantiatesReference>
              <!-- ObservationDefinition/LyophilizationAssayHomogeneity -->
              <reference
                         value="ObservationDefinition/32e29d32-6fcb-546e-24fd-52a4a4004467"/>
            </instantiatesReference>
            <status value="final"/>
            <code>
              <coding>
                <system
                        value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                <code value="Lyophilization Assay Homogeneity"/>
                <display value="Lyophilization Assay Homogeneity"/>
              </coding>
              <text value="Lyophilization Assay Homogeneity"/>
            </code>
            <subject>
              <!-- Medication/medication-batch-information-drug-pq-ex1 -->
              <reference value="Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"/>
            </subject>
            <effectiveDateTime value="2023-01-01T12:00:00Z"/>
            <performer>
              <!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
              <reference
                         value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
            </performer>
            <component>
              <code>
                <coding>
                  <system
                          value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                  <code value="SSE"/>
                  <display value="Statistically significant effects"/>
                </coding>
                <text value="Do statistically significant effects"/>
              </code>
              <valueString value="No"/>
            </component>
            <component>
              <code>
                <coding>
                  <system
                          value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                  <code value="LCL"/>
                  <display
                           value="Lower one-sided 95% confidence limit of Max Difference"/>
                </coding>
              </code>
              <valueString value="Not calculated"/>
            </component>
            <component>
              <code>
                <coding>
                  <system
                          value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                  <code value="UCL"/>
                  <display
                           value="Upper one-sided 95% confidence limit of Max Difference"/>
                </coding>
                <text
                      value="Upper one-sided 95% confidence limit of Max Difference"/>
              </code>
              <valueString value="Not calculated"/>
            </component>
            <!--  boolean?  -->
            <component>
              <code>
                <coding>
                  <system
                          value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                  <code value="Homogeneity"/>
                  <display value="Homogeneity demonstrated"/>
                </coding>
                <text value="Was Homogeneity demonstrated?"/>
              </code>
              <valueString value="Yes"/>
            </component>
          </Observation>
        </resource>
      </entry>
      <!--  MedicinalProductDefinition - the main resource in any product scenario  -->
      <entry>
        <fullUrl value="urn:uuid:a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"/>
        <!--  Section 1.1 - DP Identification  -->
        <resource>
          <MedicinalProductDefinition>
            <!-- medicinalproductdefinition-drug-product-pq-ex1 -->
            <id value="a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="MedicinalProductDefinition_a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"> </a><p><b>Generated Narrative: MedicinalProductDefinition</b><a name="a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"> </a><a name="hca0694a7a-aafa-4cbe-8135-c788a9a4d3d5"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource MedicinalProductDefinition &quot;a0694a7a-aafa-4cbe-8135-c788a9a4d3d5&quot; </p></div><p><b>description</b>: Textual description of the product</p><p><b>combinedPharmaceuticalDoseForm</b>: Gastro-resistant tablet <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (standardterms.edqm.eu#10225000)</span></p><p><b>route</b>: Oral use <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (standardterms.edqm.eu#20053000)</span></p><blockquote><p><b>name</b></p><p><b>productName</b>: Stelbat Tablets, 20mg</p><p><b>type</b>: Proprietary <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-productNameType-pq-example.html">Product Name Type - example</a>#Proprietary)</span></p><h3>Parts</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Part</b></td><td><b>Type</b></td></tr><tr><td style="display: none">*</td><td>20mg</td><td>Strength part <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://hl7.org/fhir/R5/codesystem-medicinal-product-name-part-type.html">Product Name Part Type</a>#StrengthPart)</span></td></tr></table></blockquote></div>
            </text>
            <description value="Textual description of the product"/>
            <combinedPharmaceuticalDoseForm>
              <coding>
                <system value="http://standardterms.edqm.eu"/>
                <code value="10225000"/>
                <display value="Gastro-resistant tablet"/>
              </coding>
            </combinedPharmaceuticalDoseForm>
            <route>
              <coding>
                <system value="http://standardterms.edqm.eu"/>
                <code value="20053000"/>
                <display value="Oral use"/>
              </coding>
            </route>
            <name>
              <productName value="Stelbat Tablets, 20mg"/>
              <type>
                <coding>
                  <system
                          value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-productNameType-pq-example"/>
                  <code value="Proprietary"/>
                  <display value="Proprietary"/>
                </coding>
              </type>
              <part>
                <part value="20mg"/>
                <type>
                  <coding>
                    <system
                            value="http://hl7.org/fhir/medicinal-product-name-part-type"/>
                    <code value="StrengthPart"/>
                    <display value="Strength part"/>
                  </coding>
                </type>
              </part>
            </name>
          </MedicinalProductDefinition>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:a0694a7a-aafa-4cbe-8135-c788a9a4d3d6"/>
        <resource>
          <Ingredient>
            <!-- productIngredient -->
            <id value="a0694a7a-aafa-4cbe-8135-c788a9a4d3d6"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Ingredient_a0694a7a-aafa-4cbe-8135-c788a9a4d3d6"> </a><p><b>Generated Narrative: Ingredient</b><a name="a0694a7a-aafa-4cbe-8135-c788a9a4d3d6"> </a><a name="hca0694a7a-aafa-4cbe-8135-c788a9a4d3d6"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Ingredient &quot;a0694a7a-aafa-4cbe-8135-c788a9a4d3d6&quot; </p></div><p><b>status</b>: active</p><p><b>for</b>: See on this page: MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5</p><p><b>role</b>: Active <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://hl7.org/fhir/R5/codesystem-ingredient-role.html">Ingredient Role</a>#100000072072)</span></p><blockquote><p><b>substance</b></p><h3>Codes</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Reference</b></td></tr><tr><td style="display: none">*</td><td>See on this page: SubstanceDefinition/6eb94d34-48b4-5bb0-4c05-e183d2ea3e95</td></tr></table></blockquote></div>
            </text>
            <status value="active"/>
            <for>
              <!-- MedicinalProductDefinition/medicinalproductdefinition-drug-product-pq-ex1 -->
              <reference
                         value="MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"/>
            </for>
            <role>
              <coding>
                <system value="http://hl7.org/fhir/ingredient-role"/>
                <code value="100000072072"/>
                <display value="Active"/>
              </coding>
            </role>
            <substance>
              <code>
                <reference>
                  <!-- SubstanceDefinition/substance1 -->
                  <reference
                             value="SubstanceDefinition/6eb94d34-48b4-5bb0-4c05-e183d2ea3e95"/>
                </reference>
              </code>
            </substance>
          </Ingredient>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:6eb94d34-48b4-5bb0-4c05-e183d2ea3e95"/>
        <resource>
          <SubstanceDefinition>
            <!-- substance1 -->
            <id value="6eb94d34-48b4-5bb0-4c05-e183d2ea3e95"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="SubstanceDefinition_6eb94d34-48b4-5bb0-4c05-e183d2ea3e95"> </a><p><b>Generated Narrative: SubstanceDefinition</b><a name="6eb94d34-48b4-5bb0-4c05-e183d2ea3e95"> </a><a name="hc6eb94d34-48b4-5bb0-4c05-e183d2ea3e95"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource SubstanceDefinition &quot;6eb94d34-48b4-5bb0-4c05-e183d2ea3e95&quot; </p></div><p><b>manufacturer</b>: See on this page: Organization/23dbbd32-2962-9fc3-40b1-67e864f21cd2</p><h3>Names</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Name</b></td></tr><tr><td style="display: none">*</td><td>Stelbatolol</td></tr></table></div>
            </text>
            <manufacturer>
              <!-- Organization/substance-manufacturer -->
              <reference
                         value="Organization/23dbbd32-2962-9fc3-40b1-67e864f21cd2"/>
            </manufacturer>
            <name>
              <name value="Stelbatolol"/>
            </name>
          </SubstanceDefinition>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:23dbbd32-2962-9fc3-40b1-67e864f21cd2"/>
        <resource>
          <Organization>
            <!-- substance-manufacturer -->
            <id value="23dbbd32-2962-9fc3-40b1-67e864f21cd2"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Organization_23dbbd32-2962-9fc3-40b1-67e864f21cd2"> </a><p><b>Generated Narrative: Organization</b><a name="23dbbd32-2962-9fc3-40b1-67e864f21cd2"> </a><a name="hc23dbbd32-2962-9fc3-40b1-67e864f21cd2"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Organization &quot;23dbbd32-2962-9fc3-40b1-67e864f21cd2&quot; </p></div><p><b>identifier</b>: <code>urn:oid:2.16.840.1.113883.4.82</code>/3003040516</p><p><b>active</b>: true</p><p><b>type</b>: Drug Substance Manufacture <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-pharmaceutical-organization-type.html">Pharmaceutical Organization Type Codes</a>#drug-substance-manufacture)</span></p><p><b>name</b>: AAA Molybdenum Products, Inc.</p><h3>Contacts</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Address</b></td></tr><tr><td style="display: none">*</td><td>7233 W 116th Pl Ste C Broomfield Colorado 80020 USA </td></tr></table></div>
            </text>
            <identifier>
              <!--  FDA establishment identifier  -->
              <system value="urn:oid:2.16.840.1.113883.4.82"/>
              <value value="3003040516"/>
            </identifier>
            <active value="true"/>
            <type>
              <coding>
                <system
                        value="http://terminology.hl7.org/CodeSystem/pharmaceutical-organization-type"/>
                <code value="drug-substance-manufacture"/>
                <display value="Drug Substance Manufacture"/>
              </coding>
            </type>
            <name value="AAA Molybdenum Products, Inc."/>
            <contact>
              <address>
                <line value="7233 W 116th Pl"/>
                <line value="Ste C"/>
                <city value="Broomfield"/>
                <state value="Colorado"/>
                <postalCode value="80020"/>
                <country value="USA"/>
              </address>
            </contact>
          </Organization>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:57a9af63-315d-1585-a261-0e337b289390"/>
        <resource>
          <SubstanceDefinition>
            <!-- substancedefinition-component-substance-drug-pq-ex1 -->
            <id value="57a9af63-315d-1585-a261-0e337b289390"/>
            <meta>
              <profile
                       value="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/SubstanceDefinition-component-substance-drug-pq"/>
            </meta>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="SubstanceDefinition_57a9af63-315d-1585-a261-0e337b289390"> </a><p><b>Generated Narrative: SubstanceDefinition</b><a name="57a9af63-315d-1585-a261-0e337b289390"> </a><a name="hc57a9af63-315d-1585-a261-0e337b289390"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource SubstanceDefinition &quot;57a9af63-315d-1585-a261-0e337b289390&quot; </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-SubstanceDefinition-component-substance-drug-pq.html">SubstanceDefinition - Component Substance Drug PQ</a></p></div><p><b>manufacturer</b>: See on this page: Organization/49d2f0c0-4b28-9271-8aaf-2996a8b9739c</p><h3>Names</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Name</b></td></tr><tr><td style="display: none">*</td><td>Stelbatolol</td></tr></table></div>
            </text>
            <manufacturer>
              <!-- Organization/organization-drug-pq-ex1 -->
              <reference
                         value="Organization/49d2f0c0-4b28-9271-8aaf-2996a8b9739c"/>
            </manufacturer>
            <name>
              <name value="Stelbatolol"/>
            </name>
          </SubstanceDefinition>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:49d2f0c0-4b28-9271-8aaf-2996a8b9739c"/>
        <resource>
          <Organization>
            <!-- id value="substance-manufacturer"/ -->
            <!-- organization-drug-pq-ex1 -->
            <id value="49d2f0c0-4b28-9271-8aaf-2996a8b9739c"/>
            <meta>
              <profile
                       value="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Organization-drug-pq"/>
            </meta>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Organization_49d2f0c0-4b28-9271-8aaf-2996a8b9739c"> </a><p><b>Generated Narrative: Organization</b><a name="49d2f0c0-4b28-9271-8aaf-2996a8b9739c"> </a><a name="hc49d2f0c0-4b28-9271-8aaf-2996a8b9739c"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Organization &quot;49d2f0c0-4b28-9271-8aaf-2996a8b9739c&quot; </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-Organization-drug-pq.html">Organization - Drug PQ</a></p></div><p><b>identifier</b>: <code>urn:oid:2.16.840.1.113883.4.82</code>/3003040516</p><p><b>active</b>: true</p><p><b>type</b>: Drug Substance Manufacture <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-pharmaceutical-organization-type.html">Pharmaceutical Organization Type Codes</a>#drug-substance-manufacture)</span></p><p><b>name</b>: AAA Molybdenum Products, Inc.</p><h3>Contacts</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Address</b></td></tr><tr><td style="display: none">*</td><td>7233 W 116th Pl Ste C Broomfield Colorado 80020 USA </td></tr></table></div>
            </text>
            <identifier>
              <!--  FDA establishment identifier  -->
              <system value="urn:oid:2.16.840.1.113883.4.82"/>
              <value value="3003040516"/>
            </identifier>
            <active value="true"/>
            <type>
              <coding>
                <system
                        value="http://terminology.hl7.org/CodeSystem/pharmaceutical-organization-type"/>
                <code value="drug-substance-manufacture"/>
                <display value="Drug Substance Manufacture"/>
              </coding>
            </type>
            <name value="AAA Molybdenum Products, Inc."/>
            <contact>
              <address>
                <line value="7233 W 116th Pl"/>
                <line value="Ste C"/>
                <city value="Broomfield"/>
                <state value="Colorado"/>
                <postalCode value="80020"/>
                <country value="USA"/>
              </address>
            </contact>
          </Organization>
        </resource>
      </entry>
      <!--  manufacturing plan  -->
      <entry>
        <fullUrl value="urn:uuid:bf6b038b-1334-3dd4-a552-65c169e2265a"/>
        <!--  another outer action can be the whole thing, if needed  -->
        <!--  removed the main actions for brevity (see manufacturing example)  -->
        <resource>
          <PlanDefinition>
            <id value="plandefinition-drug-pq-ex2-manufacturing-plan"/>
            <!--  indicate this is as subset of the resource. In practice it would have it all  -->
            <meta>
              <profile
                       value="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/PlanDefinition-drug-pq"/>
              <tag>
                <system
                        value="http://terminology.hl7.org/CodeSystem/v3-ObservationValue"/>
                <code value="SUBSETTED"/>
              </tag>
            </meta>
            <text>
              <status value="extensions"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="PlanDefinition_plandefinition-drug-pq-ex2-manufacturing-plan"> </a><p><b>Generated Narrative: PlanDefinition</b><a name="plandefinition-drug-pq-ex2-manufacturing-plan"> </a><a name="hcplandefinition-drug-pq-ex2-manufacturing-plan"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource PlanDefinition &quot;plandefinition-drug-pq-ex2-manufacturing-plan&quot; </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-PlanDefinition-drug-pq.html">PlanDefinition - Drug PQ</a></p><p style="margin-bottom: 0px">Tag: <span title="{http://terminology.hl7.org/CodeSystem/v3-ObservationValue http://terminology.hl7.org/CodeSystem/v3-ObservationValue}">http://terminology.hl7.org/CodeSystem/v3-ObservationValue</span></p></div><p><b>Extension - History of Process PQ</b>: This can be text about the history</p><p><b>url</b>: <code>http://example-server.com/fhir/PlanDefinition/bf6b038b-1334-3dd4-a552-65c169e2265a</code></p><p><b>title</b>: Process 1.0</p><p><b>type</b>: Workflow Definition <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.0.0/CodeSystem-plan-definition-type.html">PlanDefinitionType</a>#workflow-definition; <a href="CodeSystem-pharmaceutical-plan-type.html">Pharmaceutical Plan Type Codes</a>#manufacturing-process &quot;Manufacturing Process&quot;)</span></p><p><b>status</b>: active</p><p><b>subject</b>: See on this page: MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5</p><p><b>description</b>: Narrative description of manufacturing process (5)</p><blockquote><p><b>goal</b></p><blockquote><p><b>id</b></p>goal-control-pH</blockquote><p><b>category</b>: Physical Property <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-pharmaceutical-test-category.html">Pharmaceutical Test Category Codes</a>#C123456)</span></p><p><b>description</b>: Controls - pH <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><p><b>priority</b>: Critical <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-goalPriority-pq-example.html">Goal Priority - example</a>#critical)</span></p><h3>Targets</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Measure</b></td><td><b>Detail[x]</b></td></tr><tr><td style="display: none">*</td><td>pH must be in range 6.9 to 7.1 <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#pH &quot;pH&quot;)</span></td><td>6.9-7.1 pH</td></tr></table></blockquote><blockquote><p><b>goal</b></p><blockquote><p><b>id</b></p>goal-control-water-content</blockquote><p><b>category</b>: Physical Property <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-pharmaceutical-test-category.html">Pharmaceutical Test Category Codes</a>#C123456)</span></p><p><b>description</b>: Controls - Water Content <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><p><b>priority</b>: Critical <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-goalPriority-pq-example.html">Goal Priority - example</a>#critical)</span></p><h3>Targets</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Measure</b></td><td><b>Detail[x]</b></td></tr><tr><td style="display: none">*</td><td>Under 2% <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#WaterContent &quot;Water content&quot;)</span></td><td>?-2</td></tr></table></blockquote><blockquote><p><b>goal</b></p><blockquote><p><b>id</b></p>goal-control-particle-size</blockquote><p><b>category</b>: Physical Property <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-pharmaceutical-test-category.html">Pharmaceutical Test Category Codes</a>#C123456)</span></p><p><b>description</b>: Controls - Particle Size <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><p><b>priority</b>: Critical <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-goalPriority-pq-example.html">Goal Priority - example</a>#critical)</span></p><h3>Targets</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Measure</b></td><td><b>Detail[x]</b></td></tr><tr><td style="display: none">*</td><td>Under 200 microns <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq-example.html">Example Local Codes - Drug</a>#particle-size &quot;Particle Size&quot;)</span></td><td>?-200</td></tr></table></blockquote><blockquote><p><b>actor</b></p><h3>Options</h3><table class="grid"><tr><td style="display: none">-</td><td><b>TypeReference</b></td><td><b>Role</b></td></tr><tr><td style="display: none">*</td><td>See on this page: DeviceDefinition/82a39a18-91cf-a29d-76c1-a9e8bad9494d</td><td>Mixing Vessel <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-pharmaceutical-manufacturing-equipment-class.html">Pharmaceutical Manufacturing Equipment Class Codes</a>#mixing-vessel)</span></td></tr></table></blockquote><blockquote><p><b>actor</b></p><h3>Options</h3><table class="grid"><tr><td style="display: none">-</td><td><b>TypeReference</b></td><td><b>Role</b></td></tr><tr><td style="display: none">*</td><td>See on this page: DeviceDefinition/82a39a18-91cf-b29d-76c1-a9e8bad9494d</td><td>Receiving Vessel <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-pharmaceutical-manufacturing-equipment-class.html">Pharmaceutical Manufacturing Equipment Class Codes</a>#receiving-vessel)</span></td></tr></table></blockquote></div>
            </text>
            <extension
                       url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-history-of-process-pq">
              <valueMarkdown value="This can be text about the history"/>
            </extension>
            <!-- http://example-server.com/fhir/PlanDefinition/bf6b038b-1334-3dd4-a552-65c169e2265a -->
            <url
                 value="http://example-server.com/fhir/PlanDefinition/bf6b038b-1334-3dd4-a552-65c169e2265a"/>
            <title value="Process 1.0"/>
            <type>
              <coding>
                <system
                        value="http://terminology.hl7.org/CodeSystem/plan-definition-type"/>
                <code value="workflow-definition"/>
                <display value="Workflow Definition"/>
              </coding>
              <coding>
                <system
                        value="http://terminology.hl7.org/CodeSystem/pharmaceutical-plan-type"/>
                <code value="manufacturing-process"/>
                <display value="Manufacturing Process"/>
              </coding>
            </type>
            <status value="active"/>
            <subjectReference>
              <!-- MedicinalProductDefinition/medicinalproductdefinition-drug-product-pq-ex1 -->
              <reference
                         value="MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"/>
            </subjectReference>
            <description
                         value="Narrative description of manufacturing process (5)"/>
            <goal id="goal-control-pH">
              <category>
                <coding>
                  <system
                          value="http://terminology.hl7.org/CodeSystem/pharmaceutical-test-category"/>
                  <code value="C123456"/>
                  <display value="Physical Property"/>
                </coding>
              </category>
              <!--  this is mandatory, even though we don't really want it  -->
              <description>
                <text value="Controls - pH"/>
              </description>
              <priority>
                <coding>
                  <system
                          value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-goalPriority-pq-example"/>
                  <code value="critical"/>
                  <display value="Critical"/>
                </coding>
              </priority>
              <target>
                <measure>
                  <coding>
                    <system
                            value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                    <code value="pH"/>
                    <display value="pH"/>
                  </coding>
                  <text value="pH must be in range 6.9 to 7.1"/>
                </measure>
                <!-- detailString value="can also be a string" -->
                <detailRange>
                  <low>
                    <value value="6.9"/>
                    <unit value="pH"/>
                  </low>
                  <high>
                    <value value="7.1"/>
                    <unit value="pH"/>
                  </high>
                </detailRange>
              </target>
            </goal>
            <goal id="goal-control-water-content">
              <category>
                <coding>
                  <system
                          value="http://terminology.hl7.org/CodeSystem/pharmaceutical-test-category"/>
                  <code value="C123456"/>
                  <display value="Physical Property"/>
                </coding>
              </category>
              <!--  this is mandatory, even though we don't really want it  -->
              <description>
                <text value="Controls - Water Content"/>
              </description>
              <priority>
                <coding>
                  <system
                          value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-goalPriority-pq-example"/>
                  <code value="critical"/>
                  <display value="Critical"/>
                </coding>
              </priority>
              <target>
                <measure>
                  <coding>
                    <system
                            value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                    <code value="WaterContent"/>
                    <display value="Water content"/>
                  </coding>
                  <text value="Under 2%"/>
                </measure>
                <!-- detailString value="can also be a string" -->
                <detailRange>
                  <high>
                    <value value="2"/>
                    <unit value="%"/>
                  </high>
                </detailRange>
              </target>
            </goal>
            <goal id="goal-control-particle-size">
              <category>
                <coding>
                  <system
                          value="http://terminology.hl7.org/CodeSystem/pharmaceutical-test-category"/>
                  <code value="C123456"/>
                  <display value="Physical Property"/>
                </coding>
              </category>
              <description>
                <text value="Controls - Particle Size"/>
              </description>
              <priority>
                <coding>
                  <system
                          value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-goalPriority-pq-example"/>
                  <code value="critical"/>
                  <display value="Critical"/>
                </coding>
              </priority>
              <target>
                <measure>
                  <coding>
                    <system
                            value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"/>
                    <code value="particle-size"/>
                    <display value="Particle Size"/>
                  </coding>
                  <text value="Under 200 microns"/>
                </measure>
                <!-- detailString value="can also be a string" -->
                <detailRange>
                  <high>
                    <value value="200"/>
                    <unit value="microns"/>
                  </high>
                </detailRange>
              </target>
            </goal>
            <actor>
              <option>
                <typeReference>
                  <!-- DeviceDefinition/mixing-vessel -->
                  <reference
                             value="DeviceDefinition/82a39a18-91cf-a29d-76c1-a9e8bad9494d"/>
                </typeReference>
                <role>
                  <coding>
                    <system
                            value="http://terminology.hl7.org/CodeSystem/pharmaceutical-manufacturing-equipment-class"/>
                    <code value="mixing-vessel"/>
                    <display value="Mixing Vessel"/>
                  </coding>
                </role>
              </option>
            </actor>
            <actor>
              <option>
                <typeReference>
                  <!-- DeviceDefinition/receiving-tank -->
                  <reference
                             value="DeviceDefinition/82a39a18-91cf-b29d-76c1-a9e8bad9494d"/>
                </typeReference>
                <role>
                  <coding>
                    <system
                            value="http://terminology.hl7.org/CodeSystem/pharmaceutical-manufacturing-equipment-class"/>
                    <code value="receiving-vessel"/>
                    <display value="Receiving Vessel"/>
                  </coding>
                </role>
              </option>
            </actor>
          </PlanDefinition>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:82a39a18-91cf-a29d-76c1-a9e8bad9494d"/>
        <resource>
          <DeviceDefinition>
            <!-- mixing-vessel -->
            <id value="82a39a18-91cf-a29d-76c1-a9e8bad9494d"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="DeviceDefinition_82a39a18-91cf-a29d-76c1-a9e8bad9494d"> </a><p><b>Generated Narrative: DeviceDefinition</b><a name="82a39a18-91cf-a29d-76c1-a9e8bad9494d"> </a><a name="hc82a39a18-91cf-a29d-76c1-a9e8bad9494d"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource DeviceDefinition &quot;82a39a18-91cf-a29d-76c1-a9e8bad9494d&quot; </p></div><h3>DeviceNames</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Name</b></td><td><b>Type</b></td></tr><tr><td style="display: none">*</td><td>Mixing Vessel</td><td>registered-name</td></tr></table><h3>Classifications</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td></tr><tr><td style="display: none">*</td><td>Mixing Vessel <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-deviceType-pq-example.html">Device Type - example</a>#mixing-vessel)</span></td></tr></table><h3>Properties</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Capacity <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-device-property.html">Device Property Codes</a>#Capacity)</span></td><td>1000 litres</td></tr></table></div>
            </text>
            <deviceName>
              <name value="Mixing Vessel"/>
              <type value="registered-name"/>
            </deviceName>
            <classification>
              <type>
                <coding>
                  <system
                          value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-deviceType-pq-example"/>
                  <code value="mixing-vessel"/>
                  <display value="Mixing Vessel"/>
                </coding>
              </type>
            </classification>
            <property>
              <type>
                <!--  seems a little different to "maximum capacity  -->
                <coding>
                  <system
                          value="http://terminology.hl7.org/CodeSystem/device-property"/>
                  <code value="Capacity"/>
                  <display value="Capacity"/>
                </coding>
              </type>
              <valueQuantity>
                <value value="1000"/>
                <unit value="litres"/>
              </valueQuantity>
            </property>
          </DeviceDefinition>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:82a39a18-91cf-b29d-76c1-a9e8bad9494d"/>
        <resource>
          <DeviceDefinition>
            <!-- receiving-tank -->
            <id value="82a39a18-91cf-b29d-76c1-a9e8bad9494d"/>
            <text>
              <status value="generated"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="DeviceDefinition_82a39a18-91cf-b29d-76c1-a9e8bad9494d"> </a><p><b>Generated Narrative: DeviceDefinition</b><a name="82a39a18-91cf-b29d-76c1-a9e8bad9494d"> </a><a name="hc82a39a18-91cf-b29d-76c1-a9e8bad9494d"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource DeviceDefinition &quot;82a39a18-91cf-b29d-76c1-a9e8bad9494d&quot; </p></div><h3>DeviceNames</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Name</b></td><td><b>Type</b></td></tr><tr><td style="display: none">*</td><td>Receiving Tank</td><td>registered-name</td></tr></table><h3>Classifications</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td></tr><tr><td style="display: none">*</td><td>Receiving Tank <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-deviceType-pq-example.html">Device Type - example</a>#receiving-tank)</span></td></tr></table><h3>Properties</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Capacity <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-device-property.html">Device Property Codes</a>#Capacity)</span></td><td>1200 litres</td></tr></table></div>
            </text>
            <deviceName>
              <name value="Receiving Tank"/>
              <type value="registered-name"/>
            </deviceName>
            <classification>
              <type>
                <coding>
                  <system
                          value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-deviceType-pq-example"/>
                  <code value="receiving-tank"/>
                  <display value="Receiving Tank"/>
                </coding>
              </type>
            </classification>
            <property>
              <type>
                <!--  seems a little different to "maximum capacity  -->
                <coding>
                  <system
                          value="http://terminology.hl7.org/CodeSystem/device-property"/>
                  <code value="Capacity"/>
                  <display value="Capacity"/>
                </coding>
              </type>
              <valueQuantity>
                <value value="1200"/>
                <unit value="litres"/>
              </valueQuantity>
            </property>
          </DeviceDefinition>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:fc078762-81c5-5656-9744-13c7ad1e595b"/>
        <resource>
          <Substance>
            <!-- <id value="actual-batch-substance"/> -->
            <!-- substance-drug-pq-ex1 -->
            <id value="fc078762-81c5-5656-9744-13c7ad1e595b"/>
            <meta>
              <profile
                       value="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Substance-drug-pq"/>
            </meta>
            <text>
              <status value="extensions"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Substance_fc078762-81c5-5656-9744-13c7ad1e595b"> </a><p><b>Generated Narrative: Substance</b><a name="fc078762-81c5-5656-9744-13c7ad1e595b"> </a><a name="hcfc078762-81c5-5656-9744-13c7ad1e595b"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Substance &quot;fc078762-81c5-5656-9744-13c7ad1e595b&quot; </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-Substance-drug-pq.html">Substance - Drug PQ</a></p></div><blockquote><p><b>Medication Manufacturing Batch</b></p><blockquote><p><b>url</b></p><code>manufacturingDate</code></blockquote><p><b>value</b>: 2019-09-07</p><blockquote><p><b>url</b></p><code>batchQuantity</code></blockquote><p><b>value</b>: 5 kg</p><blockquote><p><b>url</b></p><code>batchUtilization</code></blockquote><p><b>value</b>: Development <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.0.0/CodeSystem-v3-nciThesaurus.html">NCI Thesaurus</a>#C133991)</span></p><blockquote><p><b>url</b></p><code>assignedManufacturer</code></blockquote><p><b>value</b>: See on this page: Organization/49d2f0c0-4b28-9271-8aaf-2996a8b9739c</p></blockquote><p><b>Extension - Batch Release Date PQ</b>: 2019-09-08</p><p><b>Extension - Batch Retest Date PQ</b>: 2022-09-08</p><p><b>Extension - Actual Yield PQ</b>: 4.8 kg</p><p><b>identifier</b>: CAT1</p><p><b>instance</b>: true</p><h3>Codes</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Reference</b></td></tr><tr><td style="display: none">*</td><td>See on this page: SubstanceDefinition/57a9af63-315d-1585-a261-0e337b289390</td></tr></table></div>
            </text>
            <extension
                       url="http://hl7.org/fhir/StructureDefinition/medication-manufacturingBatch">
              <extension url="manufacturingDate">
                <valueDateTime value="2019-09-07"/>
              </extension>
              <extension url="batchQuantity">
                <valueQuantity>
                  <value value="5"/>
                  <unit value="kg"/>
                </valueQuantity>
              </extension>
              <extension url="batchUtilization">
                <valueCodeableConcept>
                  <coding>
                    <system
                            value="http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"/>
                    <code value="C133991"/>
                    <display value="Development"/>
                  </coding>
                </valueCodeableConcept>
              </extension>
              <extension url="assignedManufacturer">
                <valueReference>
                  <!-- Organization/organization-drug-pq-ex1 -->
                  <reference
                             value="Organization/49d2f0c0-4b28-9271-8aaf-2996a8b9739c"/>
                </valueReference>
              </extension>
            </extension>
            <!--  local extensions  -->
            <extension
                       url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-release-date-pq">
              <valueDateTime value="2019-09-08"/>
            </extension>
            <extension
                       url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-retest-date-pq">
              <valueDateTime value="2022-09-08"/>
            </extension>
            <extension
                       url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-pq">
              <valueQuantity>
                <value value="4.8"/>
                <unit value="kg"/>
              </valueQuantity>
            </extension>
            <identifier>
              <value value="CAT1"/>
            </identifier>
            <instance value="true"/>
            <code>
              <reference>
                <!-- SubstanceDefinition/substancedefinition-component-substance-drug-pq-ex1 -->
                <reference
                           value="SubstanceDefinition/57a9af63-315d-1585-a261-0e337b289390"/>
              </reference>
            </code>
          </Substance>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:cb31d747-2338-88d5-342c-8e9c097e4dad"/>
        <resource>
          <Substance>
            <!-- actual-batch-substance-2 -->
            <id value="cb31d747-2338-88d5-342c-8e9c097e4dad"/>
            <text>
              <status value="extensions"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Substance_cb31d747-2338-88d5-342c-8e9c097e4dad"> </a><p><b>Generated Narrative: Substance</b><a name="cb31d747-2338-88d5-342c-8e9c097e4dad"> </a><a name="hccb31d747-2338-88d5-342c-8e9c097e4dad"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Substance &quot;cb31d747-2338-88d5-342c-8e9c097e4dad&quot; </p></div><blockquote><p><b>Medication Manufacturing Batch</b></p><blockquote><p><b>url</b></p><code>manufacturingDate</code></blockquote><p><b>value</b>: 2019-09-07</p><blockquote><p><b>url</b></p><code>batchQuantity</code></blockquote><p><b>value</b>: 5 kg</p><blockquote><p><b>url</b></p><code>batchUtilization</code></blockquote><p><b>value</b>: Development <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.0.0/CodeSystem-v3-nciThesaurus.html">NCI Thesaurus</a>#C133991)</span></p><blockquote><p><b>url</b></p><code>assignedManufacturer</code></blockquote><p><b>value</b>: See on this page: Organization/49d2f0c0-4b28-9271-8aaf-2996a8b9739c</p></blockquote><p><b>Extension - Batch Release Date PQ</b>: 2019-09-08</p><p><b>Extension - Batch Retest Date PQ</b>: 2022-09-08</p><p><b>Extension - Actual Yield PQ</b>: 4.8 kg</p><p><b>identifier</b>: CAT2</p><p><b>instance</b>: true</p><h3>Codes</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Reference</b></td></tr><tr><td style="display: none">*</td><td>See on this page: SubstanceDefinition/57a9af63-315d-1585-a261-0e337b289390</td></tr></table></div>
            </text>
            <extension
                       url="http://hl7.org/fhir/StructureDefinition/medication-manufacturingBatch">
              <extension url="manufacturingDate">
                <valueDateTime value="2019-09-07"/>
              </extension>
              <extension url="batchQuantity">
                <valueQuantity>
                  <value value="5"/>
                  <unit value="kg"/>
                </valueQuantity>
              </extension>
              <extension url="batchUtilization">
                <valueCodeableConcept>
                  <coding>
                    <system
                            value="http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"/>
                    <code value="C133991"/>
                    <display value="Development"/>
                  </coding>
                </valueCodeableConcept>
              </extension>
              <extension url="assignedManufacturer">
                <valueReference>
                  <!-- Organization/organization-drug-pq-ex1 -->
                  <reference
                             value="Organization/49d2f0c0-4b28-9271-8aaf-2996a8b9739c"/>
                </valueReference>
              </extension>
            </extension>
            <!--  local extensions  -->
            <extension
                       url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-release-date-pq">
              <valueDateTime value="2019-09-08"/>
            </extension>
            <extension
                       url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-retest-date-pq">
              <valueDateTime value="2022-09-08"/>
            </extension>
            <extension
                       url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-pq">
              <valueQuantity>
                <value value="4.8"/>
                <unit value="kg"/>
              </valueQuantity>
            </extension>
            <identifier>
              <value value="CAT2"/>
            </identifier>
            <instance value="true"/>
            <code>
              <reference>
                <!-- SubstanceDefinition/substancedefinition-component-substance-drug-pq-ex1 -->
                <reference
                           value="SubstanceDefinition/57a9af63-315d-1585-a261-0e337b289390"/>
              </reference>
            </code>
          </Substance>
        </resource>
      </entry>
      <entry>
        <fullUrl value="urn:uuid:1551f97b-6f6d-825e-1fb3-44b0b090808c"/>
        <resource>
          <Substance>
            <!-- actual-batch-substance-3 -->
            <id value="1551f97b-6f6d-825e-1fb3-44b0b090808c"/>
            <text>
              <status value="extensions"/>
              <div xmlns="http://www.w3.org/1999/xhtml"><a name="Substance_1551f97b-6f6d-825e-1fb3-44b0b090808c"> </a><p><b>Generated Narrative: Substance</b><a name="1551f97b-6f6d-825e-1fb3-44b0b090808c"> </a><a name="hc1551f97b-6f6d-825e-1fb3-44b0b090808c"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Substance &quot;1551f97b-6f6d-825e-1fb3-44b0b090808c&quot; </p></div><blockquote><p><b>Medication Manufacturing Batch</b></p><blockquote><p><b>url</b></p><code>manufacturingDate</code></blockquote><p><b>value</b>: 2019-09-07</p><blockquote><p><b>url</b></p><code>batchQuantity</code></blockquote><p><b>value</b>: 5 kg</p><blockquote><p><b>url</b></p><code>batchUtilization</code></blockquote><p><b>value</b>: Development <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.0.0/CodeSystem-v3-nciThesaurus.html">NCI Thesaurus</a>#C133991)</span></p><blockquote><p><b>url</b></p><code>assignedManufacturer</code></blockquote><p><b>value</b>: See on this page: Organization/49d2f0c0-4b28-9271-8aaf-2996a8b9739c</p></blockquote><p><b>Extension - Batch Release Date PQ</b>: 2019-09-08</p><p><b>Extension - Batch Retest Date PQ</b>: 2022-09-08</p><p><b>Extension - Actual Yield PQ</b>: 4.8 kg</p><p><b>identifier</b>: CAT3</p><p><b>instance</b>: true</p><h3>Codes</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Reference</b></td></tr><tr><td style="display: none">*</td><td>See on this page: SubstanceDefinition/57a9af63-315d-1585-a261-0e337b289390</td></tr></table></div>
            </text>
            <extension
                       url="http://hl7.org/fhir/StructureDefinition/medication-manufacturingBatch">
              <extension url="manufacturingDate">
                <valueDateTime value="2019-09-07"/>
              </extension>
              <extension url="batchQuantity">
                <valueQuantity>
                  <value value="5"/>
                  <unit value="kg"/>
                </valueQuantity>
              </extension>
              <extension url="batchUtilization">
                <valueCodeableConcept>
                  <coding>
                    <system
                            value="http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"/>
                    <code value="C133991"/>
                    <display value="Development"/>
                  </coding>
                </valueCodeableConcept>
              </extension>
              <extension url="assignedManufacturer">
                <valueReference>
                  <!-- Organization/organization-drug-pq-ex1 -->
                  <reference
                             value="Organization/49d2f0c0-4b28-9271-8aaf-2996a8b9739c"/>
                </valueReference>
              </extension>
            </extension>
            <!--  local extensions  -->
            <extension
                       url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-release-date-pq">
              <valueDateTime value="2019-09-08"/>
            </extension>
            <extension
                       url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-retest-date-pq">
              <valueDateTime value="2022-09-08"/>
            </extension>
            <extension
                       url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-pq">
              <valueQuantity>
                <value value="4.8"/>
                <unit value="kg"/>
              </valueQuantity>
            </extension>
            <identifier>
              <value value="CAT3"/>
            </identifier>
            <instance value="true"/>
            <code>
              <reference>
                <!-- SubstanceDefinition/substancedefinition-component-substance-drug-pq-ex1 -->
                <reference
                           value="SubstanceDefinition/57a9af63-315d-1585-a261-0e337b289390"/>
              </reference>
            </code>
          </Substance>
        </resource>
      </entry>
    </Bundle>