Pharmaceutical Quality (Industry)
1.0.0 - STU1

Pharmaceutical Quality (Industry), published by HL7 International / Biomedical Research and Regulation. This guide is not an authorized publication; it is the continuous build for version 1.0.0 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/uv-dx-pq/ and changes regularly. See the Directory of published versions

## : Example: Bundle – Reference Standards, substance - JSON Representation

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    //  Substance Reference Standard
    {
      "resourceType" : "Bundle",
      "id" : "bundle-drug-reference-standards-pq-ex2-sub",
      "meta" : {
        "profile" : [
          🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Bundle-drug-reference-standards-pq"
        ]
      },
      "type" : "collection",
      "entry" : [
        {
          "fullUrl" : "urn:uuid:2038e4c7-22b8-4c56-2d28-6c077648763f",
          "resource" : {
            "resourceType" : "PlanDefinition",
            "id" : "2038e4c7-22b8-4c56-2d28-6c077648763f",
            "meta" : // referenceProtocol
            {
              "profile" : [
                🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/PlanDefinition-drug-pq"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"PlanDefinition_2038e4c7-22b8-4c56-2d28-6c077648763f\"> </a><p><b>Generated Narrative: PlanDefinition</b><a name=\"2038e4c7-22b8-4c56-2d28-6c077648763f\"> </a><a name=\"hc2038e4c7-22b8-4c56-2d28-6c077648763f\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource PlanDefinition &quot;2038e4c7-22b8-4c56-2d28-6c077648763f&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-PlanDefinition-drug-pq.html\">PlanDefinition - Drug PQ</a></p></div><p><b>url</b>: <code>http://example-server.com/fhir/PlanDefinition/2038e4c7-22b8-4c56-2d28-6c077648763f</code></p><p><b>title</b>: S.2.S.5 Reference Standard Analysis</p><p><b>type</b>: Reference Standard Analysis <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-plan-type.html\">Pharmaceutical Plan Type Codes</a>#1244578)</span></p><p><b>status</b>: active</p><p><b>subject</b>: See on this page: SubstanceDefinition/8dae93e0-048d-35a4-71ea-7c603184a130</p><p><b>description</b>: Narrative description of analysis</p><blockquote><p><b>action</b></p><p><b>title</b>: Results for Analysis of Stelbatol Reference Standard</p><p><b>code</b>: Overall set of actions <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>Actions</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Definition[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Test <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/13033a89-927a-10e0-503e-5f901bdcb30f\">http://example-server.com/fhir/ObservationDefinition/13033a89-927a-10e0-503e-5f901bdcb30f</a></td></tr><tr><td style=\"display: none\">*</td><td>Test <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/13033a89-927a-10e0-503e-5f901bdca30f\">http://example-server.com/fhir/ObservationDefinition/13033a89-927a-10e0-503e-5f901bdca30f</a></td></tr><tr><td style=\"display: none\">*</td><td>Test <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/8395ae1d-5064-0ab7-a297-6b20285b2230\">http://example-server.com/fhir/ObservationDefinition/8395ae1d-5064-0ab7-a297-6b20285b2230</a></td></tr><tr><td style=\"display: none\">*</td><td>Test <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/8395ae1d-5064-0ab7-a297-6b20285b2231\">http://example-server.com/fhir/ObservationDefinition/8395ae1d-5064-0ab7-a297-6b20285b2231</a></td></tr><tr><td style=\"display: none\">*</td><td>Test <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/d04e0f2a-6ee7-6c2e-1db8-7df394c927b8\">http://example-server.com/fhir/ObservationDefinition/d04e0f2a-6ee7-6c2e-1db8-7df394c927b8</a></td></tr><tr><td style=\"display: none\">*</td><td>Test <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/17b322fe-53ea-6c1f-521b-3b148ac05eb4\">http://example-server.com/fhir/ObservationDefinition/17b322fe-53ea-6c1f-521b-3b148ac05eb4</a></td></tr><tr><td style=\"display: none\">*</td><td>Test <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/2daba8ca-211f-4f4b-4028-16c30fe22ee8\">http://example-server.com/fhir/ObservationDefinition/2daba8ca-211f-4f4b-4028-16c30fe22ee8</a></td></tr><tr><td style=\"display: none\">*</td><td>Test <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/0634020c-8729-99fc-7637-89799d7c445b\">http://example-server.com/fhir/ObservationDefinition/0634020c-8729-99fc-7637-89799d7c445b</a></td></tr><tr><td style=\"display: none\">*</td><td>Test <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/0634020c-8729-99fc-7637-897a9d7c445b\">http://example-server.com/fhir/ObservationDefinition/0634020c-8729-99fc-7637-897a9d7c445b</a></td></tr></table></blockquote></div>"
            },
            "url" : "http://example-server.com/fhir/PlanDefinition/2038e4c7-22b8-4c56-2d28-6c077648763f",
            "title" : "S.2.S.5 Reference Standard Analysis",
            "type" : // http://example-server.com/fhir/PlanDefinition/2038e4c7-22b8-4c56-2d28-6c077648763f
            {
              "coding" : [
                {
                  "system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-plan-type",
                  "code" : "1244578",
                  "display" : "Reference Standard Analysis"
                }
              ]
            },
            "status" : "active",
            "subjectReference" : {
              "reference" : "SubstanceDefinition/8dae93e0-048d-35a4-71ea-7c603184a130"
            },
            "description" : "Narrative description of analysis",
            "action" : [
              // SubstanceDefinition/substance1
              {
                "title" : "Results for Analysis of Stelbatol Reference Standard",
                "code" : {
                  "text" : "Overall set of actions"
                },
                "action" : [
                  {
                    "code" : {
                      "text" : "Test"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/13033a89-927a-10e0-503e-5f901bdcb30f"
                  },
                  // ObservationDefinition/TestDate
                  {
                    "code" : {
                      "text" : "Test"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/13033a89-927a-10e0-503e-5f901bdca30f"
                  },
                  // ObservationDefinition/Appearance
                  {
                    "code" : {
                      "text" : "Test"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/8395ae1d-5064-0ab7-a297-6b20285b2230"
                  },
                  // ObservationDefinition/Identification
                  {
                    "code" : {
                      "text" : "Test"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/8395ae1d-5064-0ab7-a297-6b20285b2231"
                  },
                  // ObservationDefinition/IdentificationNMR
                  {
                    "code" : {
                      "text" : "Test"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/d04e0f2a-6ee7-6c2e-1db8-7df394c927b8"
                  },
                  // ObservationDefinition/Impurities
                  {
                    "code" : {
                      "text" : "Test"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/17b322fe-53ea-6c1f-521b-3b148ac05eb4"
                  },
                  // ObservationDefinition/Water
                  {
                    "code" : {
                      "text" : "Test"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/2daba8ca-211f-4f4b-4028-16c30fe22ee8"
                  },
                  // ObservationDefinition/Solvents
                  {
                    "code" : {
                      "text" : "Test"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/0634020c-8729-99fc-7637-89799d7c445b"
                  },
                  // ObservationDefinition/Elemental
                  {
                    "code" : {
                      "text" : "Test"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/0634020c-8729-99fc-7637-897a9d7c445b"
                  }
                ]
              }
            ]
          }
        },
        // ObservationDefinition/AssignedPurity
        {
          "fullUrl" : "urn:uuid:13033a89-927a-10e0-503e-5f901bdca31f",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "13033a89-927a-10e0-503e-5f901bdca31f",
            "text" : // TestDate
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_13033a89-927a-10e0-503e-5f901bdca31f\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"13033a89-927a-10e0-503e-5f901bdca31f\"> </a><a name=\"hc13033a89-927a-10e0-503e-5f901bdca31f\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;13033a89-927a-10e0-503e-5f901bdca31f&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/13033a89-927a-10e0-503e-5f901bdca31f</code></p><p><b>title</b>: Test Date</p><p><b>status</b>: active</p><p><b>code</b>: Test Date <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Test Date)</span></p></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/13033a89-927a-10e0-503e-5f901bdca31f",
            "title" : "Test Date",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/13033a89-927a-10e0-503e-5f901bdcb30f
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Test Date",
                  "display" : "Test Date"
                }
              ],
              "text" : "Test Date"
            }
          }
        },
        {
          "fullUrl" : "urn:uuid:13033a89-927a-10e0-503e-5f901bdca30f",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "13033a89-927a-10e0-503e-5f901bdca30f",
            "text" : // Appearance
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_13033a89-927a-10e0-503e-5f901bdca30f\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"13033a89-927a-10e0-503e-5f901bdca30f\"> </a><a name=\"hc13033a89-927a-10e0-503e-5f901bdca30f\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;13033a89-927a-10e0-503e-5f901bdca30f&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/13033a89-927a-10e0-503e-5f901bdca30f</code></p><p><b>title</b>: Appearance</p><p><b>status</b>: active</p><p><b>code</b>: Appearance <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Appearance)</span></p><p><b>method</b>: Visual evaluation <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td></tr><tr><td style=\"display: none\">*</td><td/></tr></table></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/13033a89-927a-10e0-503e-5f901bdca30f",
            "title" : "Appearance",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/13033a89-927a-10e0-503e-5f901bdca30f
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Appearance",
                  "display" : "Appearance"
                }
              ],
              "text" : "Appearance"
            },
            "method" : {
              "text" : "Visual evaluation"
            },
            "qualifiedValue" : [
              {
                "extension" : [
                  {
                    "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-text-pq",
                    "valueString" : "White powder"
                  }
                ]
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:8395ae1d-5064-0ab7-a297-6b20285b2230",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "8395ae1d-5064-0ab7-a297-6b20285b2230",
            "text" : // Identification
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_8395ae1d-5064-0ab7-a297-6b20285b2230\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"8395ae1d-5064-0ab7-a297-6b20285b2230\"> </a><a name=\"hc8395ae1d-5064-0ab7-a297-6b20285b2230\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;8395ae1d-5064-0ab7-a297-6b20285b2230&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/8395ae1d-5064-0ab7-a297-6b20285b2230</code></p><p><b>title</b>: Identification</p><p><b>status</b>: active</p><p><b>code</b>: Identification (FT-IR) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Identification (FT-IR))</span></p><p><b>method</b>: FT-IR <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td></tr><tr><td style=\"display: none\">*</td><td/></tr></table></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/8395ae1d-5064-0ab7-a297-6b20285b2230",
            "title" : "Identification",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/8395ae1d-5064-0ab7-a297-6b20285b2230
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Identification (FT-IR)",
                  "display" : "Identification (FT-IR)"
                }
              ],
              "text" : "Identification (FT-IR)"
            },
            "method" : {
              "text" : "FT-IR"
            },
            "qualifiedValue" : [
              {
                "extension" : [
                  {
                    "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-text-pq",
                    "valueString" : "Consistent with structure at release; Conforms to standard at requalification"
                  }
                ]
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:8395ae1d-5064-0ab7-a297-6b20285b2231",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "8395ae1d-5064-0ab7-a297-6b20285b2231",
            "text" : // IdentificationNMR
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_8395ae1d-5064-0ab7-a297-6b20285b2231\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"8395ae1d-5064-0ab7-a297-6b20285b2231\"> </a><a name=\"hc8395ae1d-5064-0ab7-a297-6b20285b2231\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;8395ae1d-5064-0ab7-a297-6b20285b2231&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/8395ae1d-5064-0ab7-a297-6b20285b2231</code></p><p><b>title</b>: Identification (NMR)</p><p><b>status</b>: active</p><p><b>code</b>: Identification (NMR) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Identification (NMR))</span></p><p><b>method</b>: NMR spectrometry <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td></tr><tr><td style=\"display: none\">*</td><td/></tr></table></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/8395ae1d-5064-0ab7-a297-6b20285b2231",
            "title" : "Identification (NMR)",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/8395ae1d-5064-0ab7-a297-6b20285b2230
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Identification (NMR)",
                  "display" : "Identification (NMR)"
                }
              ],
              "text" : "Identification (NMR)"
            },
            "method" : {
              "text" : "NMR spectrometry"
            },
            "qualifiedValue" : [
              {
                "extension" : [
                  {
                    "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-text-pq",
                    "valueString" : "Consistent with structure"
                  }
                ]
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:d04e0f2a-6ee7-6c2e-1db8-7df394c927b8",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "d04e0f2a-6ee7-6c2e-1db8-7df394c927b8",
            "meta" : // Impurities
            {
              "profile" : [
                🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/ObservationDefinition-test-method-drug-pq"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_d04e0f2a-6ee7-6c2e-1db8-7df394c927b8\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"d04e0f2a-6ee7-6c2e-1db8-7df394c927b8\"> </a><a name=\"hcd04e0f2a-6ee7-6c2e-1db8-7df394c927b8\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;d04e0f2a-6ee7-6c2e-1db8-7df394c927b8&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ObservationDefinition-test-method-drug-pq.html\">ObservationDefinition - Test Method PQ</a></p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/d04e0f2a-6ee7-6c2e-1db8-7df394c927b8</code></p><p><b>title</b>: Organic Impurities (w/w%)</p><p><b>status</b>: active</p><p><b>code</b>: Drug Substance Related Organic impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP-s)</span></p><p><b>method</b>: HPLC <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: Impurity 1 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>range</b>: ?-0.5</p></blockquote><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: Impurity 2 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>range</b>: ?-0.5</p></blockquote><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: Impurity 3 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>range</b>: ?-0.5</p></blockquote><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: Total impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>range</b>: ?-2.0</p></blockquote><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td></tr></table></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/d04e0f2a-6ee7-6c2e-1db8-7df394c927b8",
            "title" : "Organic Impurities (w/w%)",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/d04e0f2a-6ee7-6c2e-1db8-7df394c927b8
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "DGP-s",
                  "display" : "Drug Substance Related Organic impurities"
                }
              ]
            },
            "method" : {
              "text" : "HPLC"
            },
            "qualifiedValue" : [
              {
                "appliesTo" : [
                  {
                    "text" : "Impurity 1"
                  }
                ],
                "range" : //  could be a code
                {
                  "high" : {
                    "value" : 0.5,
                    "unit" : "% w/w"
                  }
                }
              },
              {
                "appliesTo" : [
                  {
                    "text" : "Impurity 2"
                  }
                ],
                "range" : {
                  "high" : {
                    "value" : 0.5,
                    "unit" : "% w/w"
                  }
                }
              },
              {
                "appliesTo" : [
                  {
                    "text" : "Impurity 3"
                  }
                ],
                "range" : {
                  "high" : {
                    "value" : 0.5,
                    "unit" : "% w/w"
                  }
                }
              },
              {
                "appliesTo" : [
                  {
                    "text" : "Total impurities"
                  }
                ],
                "range" : {
                  "high" : {
                    "value" : 2.0,
                    "unit" : "% w/w"
                  }
                }
              }
            ],
            "component" : [
              {
                "code" : //  are expected to have a component that says what impurity this one is
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "IMP",
                      "display" : "Impurity"
                    }
                  ]
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:2daba8ca-211f-4f4b-4028-16c30fe22ee8",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "2daba8ca-211f-4f4b-4028-16c30fe22ee8",
            "text" : // Solvents
            {
              "status" : "extensions",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_2daba8ca-211f-4f4b-4028-16c30fe22ee8\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"2daba8ca-211f-4f4b-4028-16c30fe22ee8\"> </a><a name=\"hc2daba8ca-211f-4f4b-4028-16c30fe22ee8\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;2daba8ca-211f-4f4b-4028-16c30fe22ee8&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/2daba8ca-211f-4f4b-4028-16c30fe22ee8</code></p><p><b>title</b>: Residual solvents</p><p><b>status</b>: active</p><p><b>code</b>: Residual solvents <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SOL)</span></p><p><b>method</b>: GC <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><blockquote><p><b>qualifiedValue</b></p><p><b>Extension - Qualified Value Text PQ</b>: Report</p><p><b>appliesTo</b>: Solvent 1 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><blockquote><p><b>qualifiedValue</b></p><p><b>Extension - Qualified Value Text PQ</b>: Report</p><p><b>appliesTo</b>: Solvent 2 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td></tr><tr><td style=\"display: none\">*</td><td>Solvent <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SOLV)</span></td></tr></table></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/2daba8ca-211f-4f4b-4028-16c30fe22ee8",
            "title" : "Residual solvents",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/2daba8ca-211f-4f4b-4028-16c30fe22ee8
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "SOL",
                  "display" : "Residual solvents"
                }
              ]
            },
            "method" : {
              "text" : "GC"
            },
            "qualifiedValue" : [
              {
                "extension" : [
                  {
                    "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-text-pq",
                    "valueString" : "Report"
                  }
                ],
                "appliesTo" : [
                  {
                    "text" : "Solvent 1"
                  }
                ]
              },
              //  could be a code
              {
                "extension" : [
                  {
                    "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-text-pq",
                    "valueString" : "Report"
                  }
                ],
                "appliesTo" : [
                  {
                    "text" : "Solvent 2"
                  }
                ]
              }
            ],
            "component" : [
              {
                "code" : //  are expected to have a component that says what solvent this one is
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "SOLV",
                      "display" : "Solvent"
                    }
                  ]
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:17b322fe-53ea-6c1f-521b-3b148ac05eb4",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "17b322fe-53ea-6c1f-521b-3b148ac05eb4",
            "text" : // Water
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_17b322fe-53ea-6c1f-521b-3b148ac05eb4\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"17b322fe-53ea-6c1f-521b-3b148ac05eb4\"> </a><a name=\"hc17b322fe-53ea-6c1f-521b-3b148ac05eb4\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;17b322fe-53ea-6c1f-521b-3b148ac05eb4&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/17b322fe-53ea-6c1f-521b-3b148ac05eb4</code></p><p><b>title</b>: Water Content</p><p><b>status</b>: active</p><p><b>code</b>: Water Content <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#WaterContent)</span></p><p><b>method</b>: USP Karl Fischer titration <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td></tr><tr><td style=\"display: none\">*</td><td/></tr></table></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/17b322fe-53ea-6c1f-521b-3b148ac05eb4",
            "title" : "Water Content",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/17b322fe-53ea-6c1f-521b-3b148ac05eb4
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "WaterContent",
                  "display" : "Water Content"
                }
              ],
              "text" : "Water Content"
            },
            "method" : {
              "text" : "USP Karl Fischer titration"
            },
            "qualifiedValue" : [
              {
                "extension" : [
                  {
                    "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-text-pq",
                    "valueString" : "Report"
                  }
                ]
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:0634020c-8729-99fc-7637-89799d7c445b",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "0634020c-8729-99fc-7637-89799d7c445b",
            "text" : // Elemental
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_0634020c-8729-99fc-7637-89799d7c445b\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"0634020c-8729-99fc-7637-89799d7c445b\"> </a><a name=\"hc0634020c-8729-99fc-7637-89799d7c445b\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;0634020c-8729-99fc-7637-89799d7c445b&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/0634020c-8729-99fc-7637-89799d7c445b</code></p><p><b>title</b>: Elemental impurities</p><p><b>status</b>: active</p><p><b>code</b>: Elemental impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#ELE)</span></p><p><b>method</b>: ICP-MS <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td></tr><tr><td style=\"display: none\">*</td><td/></tr></table></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/0634020c-8729-99fc-7637-89799d7c445b",
            "title" : "Elemental impurities",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/0634020c-8729-99fc-7637-89799d7c445b
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "ELE",
                  "display" : "Elemental impurities"
                }
              ]
            },
            "method" : {
              "text" : "ICP-MS"
            },
            "qualifiedValue" : [
              {
                "extension" : [
                  {
                    "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-text-pq",
                    "valueString" : "Report"
                  }
                ]
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:0634020c-8729-99fc-7637-897a9d7c445b",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "0634020c-8729-99fc-7637-897a9d7c445b",
            "text" : // AssignedPurity
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_0634020c-8729-99fc-7637-897a9d7c445b\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"0634020c-8729-99fc-7637-897a9d7c445b\"> </a><a name=\"hc0634020c-8729-99fc-7637-897a9d7c445b\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;0634020c-8729-99fc-7637-897a9d7c445b&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/0634020c-8729-99fc-7637-897a9d7c445b</code></p><p><b>title</b>: Assigned Purity (w/w%)</p><p><b>status</b>: active</p><p><b>code</b>: Assigned Purity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#AssignedPurity)</span></p><p><b>method</b>: Calculation <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td><td><b>AppliesTo</b></td></tr><tr><td style=\"display: none\">*</td><td/><td>Assigned Purity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td></tr></table></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/0634020c-8729-99fc-7637-897a9d7c445b",
            "title" : "Assigned Purity (w/w%)",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/0634020c-8729-99fc-7637-89799d7c445b
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "AssignedPurity",
                  "display" : "Assigned Purity"
                }
              ]
            },
            "method" : {
              "text" : "Calculation"
            },
            "qualifiedValue" : [
              {
                "extension" : [
                  {
                    "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-text-pq",
                    "valueString" : "Report"
                  }
                ],
                "appliesTo" : [
                  {
                    "text" : "Assigned Purity"
                  }
                ]
              }
            ],
            "component" : [
              {
                "code" : //  are expected to have a component that says what impurity this one is
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "IMP",
                      "display" : "Impurity"
                    }
                  ]
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:87ef899b-14dd-26b7-7416-7ec1d01b62a1",
          "resource" : {
            "resourceType" : "Substance",
            "id" : "87ef899b-14dd-26b7-7416-7ec1d01b62a1",
            "text" : // substance-dxpq-ex1
            {
              "status" : "extensions",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Substance_87ef899b-14dd-26b7-7416-7ec1d01b62a1\"> </a><p><b>Generated Narrative: Substance</b><a name=\"87ef899b-14dd-26b7-7416-7ec1d01b62a1\"> </a><a name=\"hc87ef899b-14dd-26b7-7416-7ec1d01b62a1\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Substance &quot;87ef899b-14dd-26b7-7416-7ec1d01b62a1&quot; </p></div><blockquote><p><b>Medication Manufacturing Batch</b></p><blockquote><p><b>url</b></p><code>manufacturingDate</code></blockquote><p><b>value</b>: 2020-01</p><blockquote><p><b>url</b></p><code>batchQuantity</code></blockquote><p><b>value</b>: 120 kg</p><blockquote><p><b>url</b></p><code>batchUtilization</code></blockquote><p><b>value</b>: Production <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.0.0/CodeSystem-v3-nciThesaurus.html\">NCI Thesaurus</a>#C133990 &quot;Commercial&quot;)</span></p><blockquote><p><b>url</b></p><code>assignedManufacturer</code></blockquote><p><b>value</b>: See on this page: Organization/3d399cbc-244e-9b5f-838b-b7daa0489330</p></blockquote><p><b>Extension - Batch Release Date PQ</b>: 2019-09-08</p><p><b>Extension - Batch Retest Date PQ</b>: 2022-09-08</p><p><b>Extension - Manufacturing Process PQ</b>: See on this page: PlanDefinition/b30a1024-37db-a1bc-05e5-cc4596d92975</p><p><b>Extension - Actual Yield PQ</b>: 4.8 kg</p><p><b>identifier</b>: CAT1</p><p><b>instance</b>: true</p><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td>See on this page: SubstanceDefinition/8dae93e0-048d-35a4-71ea-7c603184a130</td></tr></table></div>"
            },
            "extension" : [
              //  was actual-batch-substance
              {
                "url" : "http://hl7.org/fhir/StructureDefinition/medication-manufacturingBatch",
                "extension" : [
                  {
                    "url" : "manufacturingDate",
                    "valueDateTime" : "2020-01"
                  },
                  {
                    "url" : "batchQuantity",
                    "valueQuantity" : {
                      "value" : 120,
                      "unit" : "kg"
                    }
                  },
                  {
                    "url" : "batchUtilization",
                    "valueCodeableConcept" : {
                      "coding" : [
                        //  could also be C185328 Stability Study?
                        {
                          "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                          "code" : "C133990",
                          "display" : "Commercial"
                        }
                      ],
                      "text" : "Production"
                    }
                  },
                  {
                    "url" : "assignedManufacturer",
                    "valueReference" : {
                      "reference" : "Organization/3d399cbc-244e-9b5f-838b-b7daa0489330"
                    }
                  }
                ]
              },
              // Organization/substance-manufacturer
              {
                "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-release-date-pq",
                "valueDateTime" : "2019-09-08"
              },
              {
                "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-retest-date-pq",
                "valueDateTime" : "2022-09-08"
              },
              {
                "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-manufacturing-process-pq",
                "valueReference" : {
                  "reference" : "PlanDefinition/b30a1024-37db-a1bc-05e5-cc4596d92975"
                }
              },
              // PlanDefinition/plandefinition-dxpq-ex4-mnf-process
              {
                "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-pq",
                "valueQuantity" : {
                  "value" : 4.8,
                  "unit" : "kg"
                }
              }
            ],
            "identifier" : [
              //  local extensions
              {
                "value" : "CAT1"
              }
            ],
            "instance" : true,
            "code" : {
              "reference" : {
                "reference" : "SubstanceDefinition/8dae93e0-048d-35a4-71ea-7c603184a130"
              }
            }
          }
        },
        // SubstanceDefinition/substance1
        {
          "fullUrl" : "urn:uuid:6412c5d4-1b7d-8405-85dc-75dbaa300ea4",
          "resource" : {
            "resourceType" : "Substance",
            "id" : "6412c5d4-1b7d-8405-85dc-75dbaa300ea4",
            "text" : // actual-batch-substance-2
            {
              "status" : "extensions",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Substance_6412c5d4-1b7d-8405-85dc-75dbaa300ea4\"> </a><p><b>Generated Narrative: Substance</b><a name=\"6412c5d4-1b7d-8405-85dc-75dbaa300ea4\"> </a><a name=\"hc6412c5d4-1b7d-8405-85dc-75dbaa300ea4\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Substance &quot;6412c5d4-1b7d-8405-85dc-75dbaa300ea4&quot; </p></div><blockquote><p><b>Medication Manufacturing Batch</b></p><blockquote><p><b>url</b></p><code>manufacturingDate</code></blockquote><p><b>value</b>: 2020-02</p><blockquote><p><b>url</b></p><code>batchQuantity</code></blockquote><p><b>value</b>: 120 kg</p><blockquote><p><b>url</b></p><code>batchUtilization</code></blockquote><p><b>value</b>: Production <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.0.0/CodeSystem-v3-nciThesaurus.html\">NCI Thesaurus</a>#C133990 &quot;Commercial&quot;)</span></p><blockquote><p><b>url</b></p><code>assignedManufacturer</code></blockquote><p><b>value</b>: See on this page: Organization/3d399cbc-244e-9b5f-838b-b7daa0489330</p></blockquote><p><b>Extension - Batch Release Date PQ</b>: 2019-09-08</p><p><b>Extension - Batch Retest Date PQ</b>: 2022-09-08</p><p><b>Extension - Actual Yield PQ</b>: 4.8 kg</p><p><b>identifier</b>: CAT2</p><p><b>instance</b>: true</p><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td>See on this page: SubstanceDefinition/8dae93e0-048d-35a4-71ea-7c603184a130</td></tr></table></div>"
            },
            "extension" : [
              {
                "url" : "http://hl7.org/fhir/StructureDefinition/medication-manufacturingBatch",
                "extension" : [
                  {
                    "url" : "manufacturingDate",
                    "valueDateTime" : "2020-02"
                  },
                  {
                    "url" : "batchQuantity",
                    "valueQuantity" : {
                      "value" : 120,
                      "unit" : "kg"
                    }
                  },
                  {
                    "url" : "batchUtilization",
                    "valueCodeableConcept" : {
                      "coding" : [
                        {
                          "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                          "code" : "C133990",
                          "display" : "Commercial"
                        }
                      ],
                      "text" : "Production"
                    }
                  },
                  {
                    "url" : "assignedManufacturer",
                    "valueReference" : {
                      "reference" : "Organization/3d399cbc-244e-9b5f-838b-b7daa0489330"
                    }
                  }
                ]
              },
              // Organization/substance-manufacturer
              {
                "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-release-date-pq",
                "valueDateTime" : "2019-09-08"
              },
              {
                "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-retest-date-pq",
                "valueDateTime" : "2022-09-08"
              },
              {
                "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-pq",
                "valueQuantity" : {
                  "value" : 4.8,
                  "unit" : "kg"
                }
              }
            ],
            "identifier" : [
              //  local extensions
              {
                "value" : "CAT2"
              }
            ],
            "instance" : true,
            "code" : {
              "reference" : {
                "reference" : "SubstanceDefinition/8dae93e0-048d-35a4-71ea-7c603184a130"
              }
            }
          }
        },
        // SubstanceDefinition/substance1
        {
          "fullUrl" : "urn:uuid:b30a1024-37db-a1bc-05e5-cc4596d92975",
          "resource" : {
            "resourceType" : "PlanDefinition",
            "id" : "b30a1024-37db-a1bc-05e5-cc4596d92975",
            "text" : // id value="manufacturingProcess"/
            // plandefinition-dxpq-ex4-mnf-process
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"PlanDefinition_b30a1024-37db-a1bc-05e5-cc4596d92975\"> </a><p><b>Generated Narrative: PlanDefinition</b><a name=\"b30a1024-37db-a1bc-05e5-cc4596d92975\"> </a><a name=\"hcb30a1024-37db-a1bc-05e5-cc4596d92975\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource PlanDefinition &quot;b30a1024-37db-a1bc-05e5-cc4596d92975&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/PlanDefinition/b30a1024-37db-a1bc-05e5-cc4596d92975</code></p><p><b>title</b>: Process 1.1</p><p><b>type</b>: Manufacturing Process <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-plan-type.html\">Pharmaceutical Plan Type Codes</a>#1244566)</span></p><p><b>status</b>: active</p><p><b>subject</b>: See on this page: SubstanceDefinition/8dae93e0-048d-35a4-71ea-7c603184a130</p></div>"
            },
            "url" : "http://example-server.com/fhir/PlanDefinition/b30a1024-37db-a1bc-05e5-cc4596d92975",
            "title" : "Process 1.1",
            "type" : // http://example-server.com/fhir/PlanDefinition/b30a1024-37db-a1bc-05e5-cc4596d92975
            {
              "coding" : [
                {
                  "system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-plan-type",
                  "code" : "1244566",
                  "display" : "Manufacturing Process"
                }
              ]
            },
            "status" : "active",
            "subjectReference" : {
              "reference" : "SubstanceDefinition/8dae93e0-048d-35a4-71ea-7c603184a130"
            }
          }
        },
        // SubstanceDefinition/substance1
        {
          "fullUrl" : "urn:uuid:8dae93e0-048d-35a4-71ea-7c603184a130",
          "resource" : {
            "resourceType" : "SubstanceDefinition",
            "id" : "8dae93e0-048d-35a4-71ea-7c603184a130",
            "text" : // substance1
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"SubstanceDefinition_8dae93e0-048d-35a4-71ea-7c603184a130\"> </a><p><b>Generated Narrative: SubstanceDefinition</b><a name=\"8dae93e0-048d-35a4-71ea-7c603184a130\"> </a><a name=\"hc8dae93e0-048d-35a4-71ea-7c603184a130\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource SubstanceDefinition &quot;8dae93e0-048d-35a4-71ea-7c603184a130&quot; </p></div><p><b>manufacturer</b>: See on this page: Organization/3d399cbc-244e-9b5f-838b-b7daa0489330</p><h3>Names</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Name</b></td></tr><tr><td style=\"display: none\">*</td><td>Stelbatolol</td></tr></table></div>"
            },
            "manufacturer" : [
              {
                "reference" : "Organization/3d399cbc-244e-9b5f-838b-b7daa0489330"
              }
            ],
            "name" : [
              // Organization/substance-manufacturer
              {
                "name" : "Stelbatolol"
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:3d399cbc-244e-9b5f-838b-b7daa0489330",
          "resource" : {
            "resourceType" : "Organization",
            "id" : "3d399cbc-244e-9b5f-838b-b7daa0489330",
            "text" : // substance-manufacturer
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Organization_3d399cbc-244e-9b5f-838b-b7daa0489330\"> </a><p><b>Generated Narrative: Organization</b><a name=\"3d399cbc-244e-9b5f-838b-b7daa0489330\"> </a><a name=\"hc3d399cbc-244e-9b5f-838b-b7daa0489330\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Organization &quot;3d399cbc-244e-9b5f-838b-b7daa0489330&quot; </p></div><p><b>identifier</b>: <code>urn:oid:2.16.840.1.113883.4.82</code>/3003040516</p><p><b>active</b>: true</p><p><b>type</b>: Drug Substance Manufacture <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-organization-type.html\">Pharmaceutical Organization Type Codes</a>#drug-substance-manufacture)</span></p><p><b>name</b>: AAA Molybdenum Products, Inc.</p><h3>Contacts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Address</b></td></tr><tr><td style=\"display: none\">*</td><td>7233 W 116th Pl Ste C Broomfield Colorado 80020 USA </td></tr></table></div>"
            },
            "identifier" : [
              {
                "system" : "urn:oid:2.16.840.1.113883.4.82",
                "value" : "3003040516"
              }
            ],
            "active" : true,
            "type" : [
              //  FDA establishment identifier
              {
                "coding" : [
                  {
                    "system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-organization-type",
                    "code" : "drug-substance-manufacture",
                    "display" : "Drug Substance Manufacture"
                  }
                ]
              }
            ],
            "name" : "AAA Molybdenum Products, Inc.",
            "contact" : [
              {
                "address" : {
                  "line" : [
                    "7233 W 116th Pl",
                    "Ste C"
                  ],
                  "city" : "Broomfield",
                  "state" : "Colorado",
                  "postalCode" : "80020",
                  "country" : "USA"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:378fbe5f-5926-3a5c-4c64-5428df877b08",
          "resource" : {
            "resourceType" : "Organization",
            "id" : "378fbe5f-5926-3a5c-4c64-5428df877b08",
            "text" : // testing lab
            // 378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\"> </a><p><b>Generated Narrative: Organization</b><a name=\"378fbe5f-5926-3a5c-4c64-5428df877b08\"> </a><a name=\"hc378fbe5f-5926-3a5c-4c64-5428df877b08\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Organization &quot;378fbe5f-5926-3a5c-4c64-5428df877b08&quot; </p></div><p><b>identifier</b>: <code>urn:oid:2.16.840.1.113883.4.82</code>/3007270600</p><p><b>active</b>: true</p><p><b>type</b>: Analytical Testing - Release <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-organization-type.html\">Pharmaceutical Organization Type Codes</a>#analytical-testing-release)</span></p><p><b>name</b>: Testing Lab</p></div>"
            },
            "identifier" : [
              {
                "system" : "urn:oid:2.16.840.1.113883.4.82",
                "value" : "3007270600"
              }
            ],
            "active" : true,
            "type" : [
              {
                "coding" : [
                  {
                    "system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-organization-type",
                    "code" : "analytical-testing-release",
                    "display" : "Analytical Testing - Release"
                  }
                ]
              }
            ],
            "name" : "Testing Lab"
          }
        },
        {
          "fullUrl" : "urn:uuid:01a5777c-4b48-a0df-2963-02cd63339006",
          "resource" : {
            "resourceType" : "DiagnosticReport",
            "id" : "referenceStandardReport",
            "text" : {
              "status" : "extensions",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"DiagnosticReport_referenceStandardReport\"> </a><p><b>Generated Narrative: DiagnosticReport</b><a name=\"referenceStandardReport\"> </a><a name=\"hcreferenceStandardReport\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource DiagnosticReport &quot;referenceStandardReport&quot; </p></div><p><b>Triggered by</b>: See on this page: PlanDefinition/2038e4c7-22b8-4c56-2d28-6c077648763f</p><p><b>status</b>: final</p><p><b>code</b>: Reference Standard Report <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-report-type.html\">Pharmaceutical Report Type Codes</a>#Reference Standard Report)</span></p><p><b>effective</b>: 2020-12</p><p><b>result</b>: </p><ul><li>See on this page: Observation/82f553f9-8458-3cf4-8379-eea5417a9de2</li><li>See on this page: Observation/82f552f9-8458-3cff-8379-eea5417a9de2</li><li>See on this page: Observation/82f552f7-8458-3cff-8379-eea5417a9de2</li><li>See on this page: Observation/83f552f7-8458-3cff-8379-eea5417a9de2</li><li>See on this page: Observation/82f552f9-8458-3cf4-8379-eea5417a9de2</li><li>See on this page: Observation/50bf6f69-a3f5-678b-469b-c5df5cca4c86</li><li>See on this page: Observation/145fd3b7-3678-867f-4298-a6c781b86de3</li><li>See on this page: Observation/81f552f9-8458-3cf4-8379-eea5417a9de2</li><li>See on this page: Observation/55c89944-60d1-4eea-a2c3-6c53e3622bc5</li><li>See on this page: Observation/adb51ab6-00a9-1078-69e5-d32c025a857c</li><li>See on this page: Observation/916a0ae2-9c43-72f0-a22a-c5f8ce902125</li><li>See on this page: Observation/55d89944-60d1-4eea-a2c3-6c53e3622bc5</li><li>See on this page: Observation/55c89954-60d1-4eea-a2c3-6c53e3622bc5</li><li>See on this page: Observation/55c89954-60d1-4eea-b2c3-6c53e3622bc5</li><li>See on this page: Observation/55c89955-60d1-4eea-b2c3-6c53e3622bc5</li><li>See on this page: Observation/55c89955-60d1-4eea-a2c3-6c53e3622bc5</li><li>See on this page: Observation/02d9e6be-833c-1c6d-a64a-baa3935c959d</li><li>See on this page: Observation/d3e572b7-14fd-744b-4123-58741d75571e</li><li>See on this page: Observation/fe6ca484-a755-9a0b-a074-b6ee0a907ff8</li><li>See on this page: Observation/02d9e6be-833c-2c6d-a64a-baa3935c959d</li><li>See on this page: Observation/da92c71f-a12a-1980-11a3-80e3d1852244</li><li>See on this page: Observation/8bf75da1-9221-66fe-6725-c64cb45a57e6</li><li>See on this page: Observation/31bfeff4-4a7d-3be5-878e-fb674d3d5487</li><li>See on this page: Observation/da92c71f-a12a-1980-21a3-80e3d1852244</li><li>See on this page: Observation/732237a9-4b3b-27cc-99ca-6b913e622a29</li><li>See on this page: Observation/52afbeb4-4958-a275-a0ca-d70b2b5240ec</li><li>See on this page: Observation/7fc395b1-59e4-78be-0512-cf92133c0fac</li><li>See on this page: Observation/732237a9-4b3b-27dc-99ca-6b913e622a29</li><li>See on this page: Observation/10b80cbd-45d3-9be1-63b9-29f04b47376c</li><li>See on this page: Observation/84f015ac-9572-324f-8013-0b999cc95bbd</li><li>See on this page: Observation/987daeaa-4c2a-72b7-780f-4a9403163a3e</li><li>See on this page: Observation/10b80cbd-45d4-9be1-63b9-29f04b47376c</li><li>See on this page: Observation/ff26533d-88a8-7f18-a275-42dc1373a388</li><li>See on this page: Observation/c99666d2-7962-9a71-58f6-7b2e5aa662f5</li><li>See on this page: Observation/c18e21d3-7113-4d08-4ff3-0c9718596f64</li><li>See on this page: Observation/ff26533d-88a8-7f18-a275-52dc1373a388</li><li>See on this page: Observation/f8160692-a7a8-3fa6-9f35-e7df35f51ac0</li><li>See on this page: Observation/a531aee9-4c21-06af-352c-a3615b5d957e</li><li>See on this page: Observation/033ce81d-5f0d-7a3e-93d3-fc64e122a1fd</li><li>See on this page: Observation/f8160692-b7a8-3fa6-9f35-e7df35f51ac0</li><li>See on this page: Observation/ba8a182e-8571-6cbd-047b-612735d599d2</li><li>See on this page: Observation/0b5b94cc-7a1a-4ada-66c7-954ceb528d67</li><li>See on this page: Observation/6afaacee-11a6-58b2-47df-5f79722c66ac</li><li>See on this page: Observation/ba8a182e-9571-6cbd-047b-612735d599d2</li><li>See on this page: Observation/c2644a86-1684-286e-00e2-dcaf907a8970</li><li>See on this page: Observation/cb5f6872-6eeb-727a-7c33-f2c438581a1c</li><li>See on this page: Observation/7faaf980-7c10-7b9a-9572-1bacd485824e</li><li>See on this page: Observation/c2644a86-1685-286e-00e2-dcaf907a8970</li><li>See on this page: Observation/ff26533d-88b8-7f18-a275-42dc1373a388</li><li>See on this page: Observation/ff26534d-88b8-7f18-a275-42dc1373a388</li><li>See on this page: Observation/ff26544d-88b8-7f18-a275-42dc1373a388</li><li>See on this page: Observation/ff36533d-88b8-7f18-a275-42dc1373a388</li></ul><p><b>conclusion</b>: The samples have been assessed and the conclusion is...</p></div>"
            },
            "extension" : [
              {
                "url" : "http://hl7.org/fhir/StructureDefinition/workflow-triggeredBy",
                "valueReference" : {
                  "reference" : "PlanDefinition/2038e4c7-22b8-4c56-2d28-6c077648763f"
                }
              }
            ],
            "status" : "final",
            "code" : // PlanDefinition/referenceProtocol
            {
              "coding" : [
                {
                  "system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-report-type",
                  "code" : "Reference Standard Report",
                  "display" : "Reference Standard Report"
                }
              ]
            },
            "effectiveDateTime" : "2020-12",
            "result" : [
              //  start of stability test
              {
                "reference" : "Observation/82f553f9-8458-3cf4-8379-eea5417a9de2"
              },
              // Observation/testDate1
              {
                "reference" : "Observation/82f552f9-8458-3cff-8379-eea5417a9de2"
              },
              // Observation/testDate2
              {
                "reference" : "Observation/82f552f7-8458-3cff-8379-eea5417a9de2"
              },
              // Observation/testDate3
              {
                "reference" : "Observation/83f552f7-8458-3cff-8379-eea5417a9de2"
              },
              // Observation/testDateSecond1
              {
                "reference" : "Observation/82f552f9-8458-3cf4-8379-eea5417a9de2"
              },
              // Observation/Observation-test-result-pq-ex2
              {
                "reference" : "Observation/50bf6f69-a3f5-678b-469b-c5df5cca4c86"
              },
              // Observation/observationDescription2
              {
                "reference" : "Observation/145fd3b7-3678-867f-4298-a6c781b86de3"
              },
              // Observation/observationDescription3
              {
                "reference" : "Observation/81f552f9-8458-3cf4-8379-eea5417a9de2"
              },
              // Observation/observationDescriptionSecond1
              {
                "reference" : "Observation/55c89944-60d1-4eea-a2c3-6c53e3622bc5"
              },
              // Observation/observationIdentification
              {
                "reference" : "Observation/adb51ab6-00a9-1078-69e5-d32c025a857c"
              },
              // Observation/observationIdentification2
              {
                "reference" : "Observation/916a0ae2-9c43-72f0-a22a-c5f8ce902125"
              },
              // Observation/observationIdentification3
              {
                "reference" : "Observation/55d89944-60d1-4eea-a2c3-6c53e3622bc5"
              },
              // Observation/observationIdentificationSecond1
              {
                "reference" : "Observation/55c89954-60d1-4eea-a2c3-6c53e3622bc5"
              },
              // Observation/observationIdentificationNMR1
              {
                "reference" : "Observation/55c89954-60d1-4eea-b2c3-6c53e3622bc5"
              },
              // Observation/observationIdentificationNMR2
              {
                "reference" : "Observation/55c89955-60d1-4eea-b2c3-6c53e3622bc5"
              },
              // Observation/observationIdentificationNMR3
              {
                "reference" : "Observation/55c89955-60d1-4eea-a2c3-6c53e3622bc5"
              },
              // Observation/observationIdentificationNMRSecond1
              {
                "reference" : "Observation/02d9e6be-833c-1c6d-a64a-baa3935c959d"
              },
              // Observation/observationDegradation-imp1
              {
                "reference" : "Observation/d3e572b7-14fd-744b-4123-58741d75571e"
              },
              // Observation/observationDegradation-imp1-2
              {
                "reference" : "Observation/fe6ca484-a755-9a0b-a074-b6ee0a907ff8"
              },
              // Observation/observationDegradation-imp1-3
              {
                "reference" : "Observation/02d9e6be-833c-2c6d-a64a-baa3935c959d"
              },
              // Observation/observationDegradation-imp1Second
              {
                "reference" : "Observation/da92c71f-a12a-1980-11a3-80e3d1852244"
              },
              // Observation/observationDegradation-imp2
              {
                "reference" : "Observation/8bf75da1-9221-66fe-6725-c64cb45a57e6"
              },
              // Observation/observationDegradation-imp2-2
              {
                "reference" : "Observation/31bfeff4-4a7d-3be5-878e-fb674d3d5487"
              },
              // Observation/observationDegradation-imp2-3
              {
                "reference" : "Observation/da92c71f-a12a-1980-21a3-80e3d1852244"
              },
              // Observation/observationDegradation-imp2Second
              {
                "reference" : "Observation/732237a9-4b3b-27cc-99ca-6b913e622a29"
              },
              // Observation/observationDegradation-imp3
              {
                "reference" : "Observation/52afbeb4-4958-a275-a0ca-d70b2b5240ec"
              },
              // Observation/observationDegradation-imp3-2
              {
                "reference" : "Observation/7fc395b1-59e4-78be-0512-cf92133c0fac"
              },
              // Observation/observationDegradation-imp3-3
              {
                "reference" : "Observation/732237a9-4b3b-27dc-99ca-6b913e622a29"
              },
              // Observation/observationDegradation-imp3Second
              {
                "reference" : "Observation/10b80cbd-45d3-9be1-63b9-29f04b47376c"
              },
              // Observation/observationDegradation-imp-total
              {
                "reference" : "Observation/84f015ac-9572-324f-8013-0b999cc95bbd"
              },
              // Observation/observationDegradation-imp-total-2
              {
                "reference" : "Observation/987daeaa-4c2a-72b7-780f-4a9403163a3e"
              },
              // Observation/observationDegradation-imp-total-3
              {
                "reference" : "Observation/10b80cbd-45d4-9be1-63b9-29f04b47376c"
              },
              // Observation/observationDegradation-imp-totalSecond
              {
                "reference" : "Observation/ff26533d-88a8-7f18-a275-42dc1373a388"
              },
              // Observation/observationElemental
              {
                "reference" : "Observation/c99666d2-7962-9a71-58f6-7b2e5aa662f5"
              },
              // Observation/observationElemental2
              {
                "reference" : "Observation/c18e21d3-7113-4d08-4ff3-0c9718596f64"
              },
              // Observation/observationElemental3
              {
                "reference" : "Observation/ff26533d-88a8-7f18-a275-52dc1373a388"
              },
              // Observation/observationElementalSecond
              {
                "reference" : "Observation/f8160692-a7a8-3fa6-9f35-e7df35f51ac0"
              },
              // Observation/observationSolvents-sol1
              {
                "reference" : "Observation/a531aee9-4c21-06af-352c-a3615b5d957e"
              },
              // Observation/observationSolvents-sol1-2
              {
                "reference" : "Observation/033ce81d-5f0d-7a3e-93d3-fc64e122a1fd"
              },
              // Observation/observationSolvents-sol1-3
              {
                "reference" : "Observation/f8160692-b7a8-3fa6-9f35-e7df35f51ac0"
              },
              // Observation/observationSolvents-sol1Second
              {
                "reference" : "Observation/ba8a182e-8571-6cbd-047b-612735d599d2"
              },
              // Observation/observationSolvents-sol2
              {
                "reference" : "Observation/0b5b94cc-7a1a-4ada-66c7-954ceb528d67"
              },
              // Observation/observationSolvents-sol2-2
              {
                "reference" : "Observation/6afaacee-11a6-58b2-47df-5f79722c66ac"
              },
              // Observation/observationSolvents-sol2-3
              {
                "reference" : "Observation/ba8a182e-9571-6cbd-047b-612735d599d2"
              },
              // Observation/observationSolvents-sol2Second
              {
                "reference" : "Observation/c2644a86-1684-286e-00e2-dcaf907a8970"
              },
              // Observation/observationWater
              {
                "reference" : "Observation/cb5f6872-6eeb-727a-7c33-f2c438581a1c"
              },
              // Observation/observationWater2
              {
                "reference" : "Observation/7faaf980-7c10-7b9a-9572-1bacd485824e"
              },
              // Observation/observationWater3
              {
                "reference" : "Observation/c2644a86-1685-286e-00e2-dcaf907a8970"
              },
              // Observation/observationWaterSecond
              {
                "reference" : "Observation/ff26533d-88b8-7f18-a275-42dc1373a388"
              },
              // Observation/observationAssignedPurity1
              {
                "reference" : "Observation/ff26534d-88b8-7f18-a275-42dc1373a388"
              },
              // Observation/observationAssignedPurity2
              {
                "reference" : "Observation/ff26544d-88b8-7f18-a275-42dc1373a388"
              },
              // Observation/observationAssignedPurity3
              {
                "reference" : "Observation/ff36533d-88b8-7f18-a275-42dc1373a388"
              }
            ],
            "conclusion" : "The samples have been assessed and the conclusion is..."
          }
        },
        // Observation/observationAssignedPurity1second
        {
          "fullUrl" : "urn:uuid:82f553f9-8458-3cf4-8379-eea5417a9de2",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "82f553f9-8458-3cf4-8379-eea5417a9de2",
            "meta" : // testDate1
            {
              "profile" : [
                🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Observation-test-result-drug-pq"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_82f553f9-8458-3cf4-8379-eea5417a9de2\"> </a><p><b>Generated Narrative: Observation</b><a name=\"82f553f9-8458-3cf4-8379-eea5417a9de2\"> </a><a name=\"hc82f553f9-8458-3cf4-8379-eea5417a9de2\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;82f553f9-8458-3cf4-8379-eea5417a9de2&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-Observation-test-result-drug-pq.html\">Observation - Test Result Drug PQ</a></p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/13033a89-927a-10e0-503e-5f901bdca31f</p><p><b>status</b>: final</p><p><b>code</b>: est Date <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Test Date &quot;Test Date&quot;)</span></p><p><b>subject</b>: See on this page: Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 2021-07</p></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/13033a89-927a-10e0-503e-5f901bdca31f"
            },
            "status" : "final",
            "code" : // ObservationDefinition/TestDate
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Test Date",
                  "display" : "Test Date"
                }
              ],
              "text" : "est Date"
            },
            "subject" : {
              "reference" : "Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/substance-dxpq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueDateTime" : "2021-07"
          }
        },
        // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "fullUrl" : "urn:uuid:82f552f9-8458-3cff-8379-eea5417a9de2",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "82f552f9-8458-3cff-8379-eea5417a9de2",
            "meta" : // testDate2
            //  was observationDescription
            {
              "profile" : [
                🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Observation-test-result-drug-pq"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_82f552f9-8458-3cff-8379-eea5417a9de2\"> </a><p><b>Generated Narrative: Observation</b><a name=\"82f552f9-8458-3cff-8379-eea5417a9de2\"> </a><a name=\"hc82f552f9-8458-3cff-8379-eea5417a9de2\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;82f552f9-8458-3cff-8379-eea5417a9de2&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-Observation-test-result-drug-pq.html\">Observation - Test Result Drug PQ</a></p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/13033a89-927a-10e0-503e-5f901bdca31f</p><p><b>status</b>: final</p><p><b>code</b>: Test Date <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Test Date)</span></p><p><b>subject</b>: See on this page: Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 2022-07</p></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/13033a89-927a-10e0-503e-5f901bdca31f"
            },
            "status" : "final",
            "code" : // ObservationDefinition/TestDate
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Test Date",
                  "display" : "Test Date"
                }
              ],
              "text" : "Test Date"
            },
            "subject" : {
              "reference" : "Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/substance-dxpq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueDateTime" : "2022-07"
          }
        },
        // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "fullUrl" : "urn:uuid:82f552f7-8458-3cff-8379-eea5417a9de2",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "82f552f7-8458-3cff-8379-eea5417a9de2",
            "meta" : // testDate3
            //  was observationDescription
            {
              "profile" : [
                🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Observation-test-result-drug-pq"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_82f552f7-8458-3cff-8379-eea5417a9de2\"> </a><p><b>Generated Narrative: Observation</b><a name=\"82f552f7-8458-3cff-8379-eea5417a9de2\"> </a><a name=\"hc82f552f7-8458-3cff-8379-eea5417a9de2\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;82f552f7-8458-3cff-8379-eea5417a9de2&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-Observation-test-result-drug-pq.html\">Observation - Test Result Drug PQ</a></p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/13033a89-927a-10e0-503e-5f901bdca31f</p><p><b>status</b>: final</p><p><b>code</b>: Test Date <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Test Date)</span></p><p><b>subject</b>: See on this page: Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 2023-07</p></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/13033a89-927a-10e0-503e-5f901bdca31f"
            },
            "status" : "final",
            "code" : // ObservationDefinition/TestDate
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Test Date",
                  "display" : "Test Date"
                }
              ],
              "text" : "Test Date"
            },
            "subject" : {
              "reference" : "Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/substance-dxpq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueDateTime" : "2023-07"
          }
        },
        // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "fullUrl" : "urn:uuid:83f552f7-8458-3cff-8379-eea5417a9de2",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "83f552f7-8458-3cff-8379-eea5417a9de2",
            "meta" : // testDateSecond1
            {
              "profile" : [
                🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Observation-test-result-drug-pq"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_83f552f7-8458-3cff-8379-eea5417a9de2\"> </a><p><b>Generated Narrative: Observation</b><a name=\"83f552f7-8458-3cff-8379-eea5417a9de2\"> </a><a name=\"hc83f552f7-8458-3cff-8379-eea5417a9de2\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;83f552f7-8458-3cff-8379-eea5417a9de2&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-Observation-test-result-drug-pq.html\">Observation - Test Result Drug PQ</a></p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/13033a89-927a-10e0-503e-5f901bdca31f</p><p><b>status</b>: final</p><p><b>code</b>: Test Date <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Test Date)</span></p><p><b>subject</b>: See on this page: Substance/6412c5d4-1b7d-8405-85dc-75dbaa300ea4</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 2024-07</p></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/13033a89-927a-10e0-503e-5f901bdca31f"
            },
            "status" : "final",
            "code" : // ObservationDefinition/TestDate
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Test Date",
                  "display" : "Test Date"
                }
              ],
              "text" : "Test Date"
            },
            "subject" : {
              "reference" : "Substance/6412c5d4-1b7d-8405-85dc-75dbaa300ea4"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/actual-batch-substance-2
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueDateTime" : "2024-07"
          }
        },
        // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "fullUrl" : "urn:uuid:82f552f9-8458-3cf4-8379-eea5417a9de2",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "82f552f9-8458-3cf4-8379-eea5417a9de2",
            "meta" : // Observation-test-result-pq-ex2
            {
              "profile" : [
                🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Observation-test-result-drug-pq"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_82f552f9-8458-3cf4-8379-eea5417a9de2\"> </a><p><b>Generated Narrative: Observation</b><a name=\"82f552f9-8458-3cf4-8379-eea5417a9de2\"> </a><a name=\"hc82f552f9-8458-3cf4-8379-eea5417a9de2\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;82f552f9-8458-3cf4-8379-eea5417a9de2&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-Observation-test-result-drug-pq.html\">Observation - Test Result Drug PQ</a></p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/13033a89-927a-10e0-503e-5f901bdca30f</p><p><b>status</b>: final</p><p><b>code</b>: Appearance <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Appearance)</span></p><p><b>subject</b>: See on this page: Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: White Powder</p></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/13033a89-927a-10e0-503e-5f901bdca30f"
            },
            "status" : "final",
            "code" : // ObservationDefinition/Appearance
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Appearance",
                  "display" : "Appearance"
                }
              ],
              "text" : "Appearance"
            },
            "subject" : {
              "reference" : "Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/substance-dxpq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueString" : "White Powder"
          }
        },
        // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "fullUrl" : "urn:uuid:50bf6f69-a3f5-678b-469b-c5df5cca4c86",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "50bf6f69-a3f5-678b-469b-c5df5cca4c86",
            "text" : // observationDescription2
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_50bf6f69-a3f5-678b-469b-c5df5cca4c86\"> </a><p><b>Generated Narrative: Observation</b><a name=\"50bf6f69-a3f5-678b-469b-c5df5cca4c86\"> </a><a name=\"hc50bf6f69-a3f5-678b-469b-c5df5cca4c86\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;50bf6f69-a3f5-678b-469b-c5df5cca4c86&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/13033a89-927a-10e0-503e-5f901bdca30f</p><p><b>status</b>: final</p><p><b>code</b>: Description <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DESC)</span></p><p><b>subject</b>: See on this page: Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: White Powder</p></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/13033a89-927a-10e0-503e-5f901bdca30f"
            },
            "status" : "final",
            "code" : // ObservationDefinition/Appearance
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "DESC",
                  "display" : "Description"
                }
              ],
              "text" : "Description"
            },
            "subject" : {
              "reference" : "Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/substance-dxpq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueString" : "White Powder"
          }
        },
        // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "fullUrl" : "urn:uuid:145fd3b7-3678-867f-4298-a6c781b86de3",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "145fd3b7-3678-867f-4298-a6c781b86de3",
            "text" : // observationDescription3
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_145fd3b7-3678-867f-4298-a6c781b86de3\"> </a><p><b>Generated Narrative: Observation</b><a name=\"145fd3b7-3678-867f-4298-a6c781b86de3\"> </a><a name=\"hc145fd3b7-3678-867f-4298-a6c781b86de3\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;145fd3b7-3678-867f-4298-a6c781b86de3&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/13033a89-927a-10e0-503e-5f901bdca30f</p><p><b>status</b>: final</p><p><b>code</b>: Description <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DESC)</span></p><p><b>subject</b>: See on this page: Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: White Powder</p></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/13033a89-927a-10e0-503e-5f901bdca30f"
            },
            "status" : "final",
            "code" : // ObservationDefinition/Appearance
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "DESC",
                  "display" : "Description"
                }
              ],
              "text" : "Description"
            },
            "subject" : {
              "reference" : "Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/substance-dxpq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueString" : "White Powder"
          }
        },
        // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "fullUrl" : "urn:uuid:81f552f9-8458-3cf4-8379-eea5417a9de2",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "81f552f9-8458-3cf4-8379-eea5417a9de2",
            "meta" : // observationDescriptionSecond1
            {
              "profile" : [
                🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Observation-test-result-drug-pq"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_81f552f9-8458-3cf4-8379-eea5417a9de2\"> </a><p><b>Generated Narrative: Observation</b><a name=\"81f552f9-8458-3cf4-8379-eea5417a9de2\"> </a><a name=\"hc81f552f9-8458-3cf4-8379-eea5417a9de2\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;81f552f9-8458-3cf4-8379-eea5417a9de2&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-Observation-test-result-drug-pq.html\">Observation - Test Result Drug PQ</a></p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/13033a89-927a-10e0-503e-5f901bdca30f</p><p><b>status</b>: final</p><p><b>code</b>: Appearance <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Appearance)</span></p><p><b>subject</b>: See on this page: Substance/6412c5d4-1b7d-8405-85dc-75dbaa300ea4</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: Off-white Powder</p></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/13033a89-927a-10e0-503e-5f901bdca30f"
            },
            "status" : "final",
            "code" : // ObservationDefinition/Appearance
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Appearance",
                  "display" : "Appearance"
                }
              ],
              "text" : "Appearance"
            },
            "subject" : {
              "reference" : "Substance/6412c5d4-1b7d-8405-85dc-75dbaa300ea4"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/actual-batch-substance-2
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueString" : "Off-white Powder"
          }
        },
        // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "fullUrl" : "urn:uuid:55c89944-60d1-4eea-a2c3-6c53e3622bc5",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "55c89944-60d1-4eea-a2c3-6c53e3622bc5",
            "text" : // observationIdentification
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_55c89944-60d1-4eea-a2c3-6c53e3622bc5\"> </a><p><b>Generated Narrative: Observation</b><a name=\"55c89944-60d1-4eea-a2c3-6c53e3622bc5\"> </a><a name=\"hc55c89944-60d1-4eea-a2c3-6c53e3622bc5\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;55c89944-60d1-4eea-a2c3-6c53e3622bc5&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8395ae1d-5064-0ab7-a297-6b20285b2230</p><p><b>status</b>: final</p><p><b>code</b>: Identification <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IDT)</span></p><p><b>subject</b>: See on this page: Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: Consistent with structure</p></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/8395ae1d-5064-0ab7-a297-6b20285b2230"
            },
            "status" : "final",
            "code" : // ObservationDefinition/Identification
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "IDT",
                  "display" : "Identification"
                }
              ],
              "text" : "Identification"
            },
            "subject" : {
              "reference" : "Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/substance-dxpq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueString" : "Consistent with structure"
          }
        },
        // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "fullUrl" : "urn:uuid:adb51ab6-00a9-1078-69e5-d32c025a857c",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "adb51ab6-00a9-1078-69e5-d32c025a857c",
            "text" : // observationIdentification2
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_adb51ab6-00a9-1078-69e5-d32c025a857c\"> </a><p><b>Generated Narrative: Observation</b><a name=\"adb51ab6-00a9-1078-69e5-d32c025a857c\"> </a><a name=\"hcadb51ab6-00a9-1078-69e5-d32c025a857c\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;adb51ab6-00a9-1078-69e5-d32c025a857c&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8395ae1d-5064-0ab7-a297-6b20285b2230</p><p><b>status</b>: final</p><p><b>code</b>: Identification <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IDT)</span></p><p><b>subject</b>: See on this page: Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: Conforms to standard</p></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/8395ae1d-5064-0ab7-a297-6b20285b2230"
            },
            "status" : "final",
            "code" : // ObservationDefinition/Identification
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "IDT",
                  "display" : "Identification"
                }
              ],
              "text" : "Identification"
            },
            "subject" : {
              "reference" : "Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/substance-dxpq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueString" : "Conforms to standard"
          }
        },
        // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "fullUrl" : "urn:uuid:916a0ae2-9c43-72f0-a22a-c5f8ce902125",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "916a0ae2-9c43-72f0-a22a-c5f8ce902125",
            "text" : // observationIdentification3
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_916a0ae2-9c43-72f0-a22a-c5f8ce902125\"> </a><p><b>Generated Narrative: Observation</b><a name=\"916a0ae2-9c43-72f0-a22a-c5f8ce902125\"> </a><a name=\"hc916a0ae2-9c43-72f0-a22a-c5f8ce902125\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;916a0ae2-9c43-72f0-a22a-c5f8ce902125&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8395ae1d-5064-0ab7-a297-6b20285b2230</p><p><b>status</b>: final</p><p><b>code</b>: Identification <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IDT)</span></p><p><b>subject</b>: See on this page: Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: Conforms to standard <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/8395ae1d-5064-0ab7-a297-6b20285b2230"
            },
            "status" : "final",
            "code" : // ObservationDefinition/Identification
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "IDT",
                  "display" : "Identification"
                }
              ],
              "text" : "Identification"
            },
            "subject" : {
              "reference" : "Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/substance-dxpq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueCodeableConcept" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "text" : "Conforms to standard"
            }
          }
        },
        {
          "fullUrl" : "urn:uuid:55d89944-60d1-4eea-a2c3-6c53e3622bc5",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "55d89944-60d1-4eea-a2c3-6c53e3622bc5",
            "text" : // observationIdentificationSecond1
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_55d89944-60d1-4eea-a2c3-6c53e3622bc5\"> </a><p><b>Generated Narrative: Observation</b><a name=\"55d89944-60d1-4eea-a2c3-6c53e3622bc5\"> </a><a name=\"hc55d89944-60d1-4eea-a2c3-6c53e3622bc5\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;55d89944-60d1-4eea-a2c3-6c53e3622bc5&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8395ae1d-5064-0ab7-a297-6b20285b2230</p><p><b>status</b>: final</p><p><b>code</b>: Identification <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IDT)</span></p><p><b>subject</b>: See on this page: Substance/6412c5d4-1b7d-8405-85dc-75dbaa300ea4</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: Conforms to standard</p></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/8395ae1d-5064-0ab7-a297-6b20285b2230"
            },
            "status" : "final",
            "code" : // ObservationDefinition/Identification
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "IDT",
                  "display" : "Identification"
                }
              ],
              "text" : "Identification"
            },
            "subject" : {
              "reference" : "Substance/6412c5d4-1b7d-8405-85dc-75dbaa300ea4"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/actual-batch-substance-2
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueString" : "Conforms to standard"
          }
        },
        // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "fullUrl" : "urn:uuid:55c89954-60d1-4eea-a2c3-6c53e3622bc5",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "55c89954-60d1-4eea-a2c3-6c53e3622bc5",
            "text" : // observationIdentificationNMR1
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_55c89954-60d1-4eea-a2c3-6c53e3622bc5\"> </a><p><b>Generated Narrative: Observation</b><a name=\"55c89954-60d1-4eea-a2c3-6c53e3622bc5\"> </a><a name=\"hc55c89954-60d1-4eea-a2c3-6c53e3622bc5\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;55c89954-60d1-4eea-a2c3-6c53e3622bc5&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8395ae1d-5064-0ab7-a297-6b20285b2231</p><p><b>status</b>: final</p><p><b>code</b>: Identification (NMR) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Identification (NMR))</span></p><p><b>subject</b>: See on this page: Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: Consistent with structure</p></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/8395ae1d-5064-0ab7-a297-6b20285b2231"
            },
            "status" : "final",
            "code" : // ObservationDefinition/IdentificationNMR
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Identification (NMR)",
                  "display" : "Identification (NMR)"
                }
              ],
              "text" : "Identification (NMR)"
            },
            "subject" : {
              "reference" : "Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/substance-dxpq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueString" : "Consistent with structure"
          }
        },
        // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "fullUrl" : "urn:uuid:55c89954-60d1-4eea-b2c3-6c53e3622bc5",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "55c89954-60d1-4eea-b2c3-6c53e3622bc5",
            "text" : // observationIdentificationNMR2
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_55c89954-60d1-4eea-b2c3-6c53e3622bc5\"> </a><p><b>Generated Narrative: Observation</b><a name=\"55c89954-60d1-4eea-b2c3-6c53e3622bc5\"> </a><a name=\"hc55c89954-60d1-4eea-b2c3-6c53e3622bc5\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;55c89954-60d1-4eea-b2c3-6c53e3622bc5&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8395ae1d-5064-0ab7-a297-6b20285b2231</p><p><b>status</b>: final</p><p><b>code</b>: Identification (NMR) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Identification (NMR))</span></p><p><b>subject</b>: See on this page: Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>dataAbsentReason</b>: Not tested <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.0.0/CodeSystem-data-absent-reason.html\">DataAbsentReason</a>#not-performed &quot;Not Performed&quot;)</span></p></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/8395ae1d-5064-0ab7-a297-6b20285b2231"
            },
            "status" : "final",
            "code" : // ObservationDefinition/IdentificationNMR
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Identification (NMR)",
                  "display" : "Identification (NMR)"
                }
              ],
              "text" : "Identification (NMR)"
            },
            "subject" : {
              "reference" : "Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/substance-dxpq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "dataAbsentReason" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "coding" : [
                {
                  "system" : "http://terminology.hl7.org/CodeSystem/data-absent-reason",
                  "code" : "not-performed",
                  "display" : "Not Performed"
                }
              ],
              "text" : "Not tested"
            }
          }
        },
        {
          "fullUrl" : "urn:uuid:55c89955-60d1-4eea-b2c3-6c53e3622bc5",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "55c89955-60d1-4eea-b2c3-6c53e3622bc5",
            "text" : // observationIdentificationNMR3
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_55c89955-60d1-4eea-b2c3-6c53e3622bc5\"> </a><p><b>Generated Narrative: Observation</b><a name=\"55c89955-60d1-4eea-b2c3-6c53e3622bc5\"> </a><a name=\"hc55c89955-60d1-4eea-b2c3-6c53e3622bc5\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;55c89955-60d1-4eea-b2c3-6c53e3622bc5&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8395ae1d-5064-0ab7-a297-6b20285b2231</p><p><b>status</b>: final</p><p><b>code</b>: Identification (NMR) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Identification (NMR))</span></p><p><b>subject</b>: See on this page: Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>dataAbsentReason</b>: Not tested <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.0.0/CodeSystem-data-absent-reason.html\">DataAbsentReason</a>#not-performed &quot;Not Performed&quot;)</span></p></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/8395ae1d-5064-0ab7-a297-6b20285b2231"
            },
            "status" : "final",
            "code" : // ObservationDefinition/IdentificationNMR
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Identification (NMR)",
                  "display" : "Identification (NMR)"
                }
              ],
              "text" : "Identification (NMR)"
            },
            "subject" : {
              "reference" : "Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/substance-dxpq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "dataAbsentReason" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "coding" : [
                {
                  "system" : "http://terminology.hl7.org/CodeSystem/data-absent-reason",
                  "code" : "not-performed",
                  "display" : "Not Performed"
                }
              ],
              "text" : "Not tested"
            }
          }
        },
        {
          "fullUrl" : "urn:uuid:55c89955-60d1-4eea-a2c3-6c53e3622bc5",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "55c89955-60d1-4eea-a2c3-6c53e3622bc5",
            "text" : // observationIdentificationNMRSecond1
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_55c89955-60d1-4eea-a2c3-6c53e3622bc5\"> </a><p><b>Generated Narrative: Observation</b><a name=\"55c89955-60d1-4eea-a2c3-6c53e3622bc5\"> </a><a name=\"hc55c89955-60d1-4eea-a2c3-6c53e3622bc5\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;55c89955-60d1-4eea-a2c3-6c53e3622bc5&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/8395ae1d-5064-0ab7-a297-6b20285b2231</p><p><b>status</b>: final</p><p><b>code</b>: Identification (NMR) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Identification (NMR))</span></p><p><b>subject</b>: See on this page: Substance/6412c5d4-1b7d-8405-85dc-75dbaa300ea4</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: Consistent with structure</p></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/8395ae1d-5064-0ab7-a297-6b20285b2231"
            },
            "status" : "final",
            "code" : // ObservationDefinition/IdentificationNMR
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Identification (NMR)",
                  "display" : "Identification (NMR)"
                }
              ],
              "text" : "Identification (NMR)"
            },
            "subject" : {
              "reference" : "Substance/6412c5d4-1b7d-8405-85dc-75dbaa300ea4"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/actual-batch-substance-2
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueString" : "Consistent with structure"
          }
        },
        // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "fullUrl" : "urn:uuid:02d9e6be-833c-1c6d-a64a-baa3935c959d",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "02d9e6be-833c-1c6d-a64a-baa3935c959d",
            "text" : // observationDegradation-imp1
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_02d9e6be-833c-1c6d-a64a-baa3935c959d\"> </a><p><b>Generated Narrative: Observation</b><a name=\"02d9e6be-833c-1c6d-a64a-baa3935c959d\"> </a><a name=\"hc02d9e6be-833c-1c6d-a64a-baa3935c959d\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;02d9e6be-833c-1c6d-a64a-baa3935c959d&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/d04e0f2a-6ee7-6c2e-1db8-7df394c927b8</p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: See on this page: Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: &lt;0.5 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 1 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/d04e0f2a-6ee7-6c2e-1db8-7df394c927b8"
            },
            "status" : "final",
            "code" : // ObservationDefinition/Impurities
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Impurities",
                  "display" : "Impurities"
                }
              ],
              "text" : "Impurities"
            },
            "subject" : {
              "reference" : "Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/substance-dxpq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 0.5,
              "comparator" : "<",
              "unit" : "% w/w",
              "system" : "http://unitsofmeasure.org",
              "code" : "%"
            },
            "component" : [
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "IMP",
                      "display" : "Impurity"
                    }
                  ]
                },
                "valueCodeableConcept" : {
                  "text" : "Impurity 1"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:d3e572b7-14fd-744b-4123-58741d75571e",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "d3e572b7-14fd-744b-4123-58741d75571e",
            "text" : // observationDegradation-imp1-2
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_d3e572b7-14fd-744b-4123-58741d75571e\"> </a><p><b>Generated Narrative: Observation</b><a name=\"d3e572b7-14fd-744b-4123-58741d75571e\"> </a><a name=\"hcd3e572b7-14fd-744b-4123-58741d75571e\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;d3e572b7-14fd-744b-4123-58741d75571e&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/d04e0f2a-6ee7-6c2e-1db8-7df394c927b8</p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: See on this page: Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: &lt;0.4 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 1 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/d04e0f2a-6ee7-6c2e-1db8-7df394c927b8"
            },
            "status" : "final",
            "code" : // ObservationDefinition/Impurities
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Impurities",
                  "display" : "Impurities"
                }
              ],
              "text" : "Impurities"
            },
            "subject" : {
              "reference" : "Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/substance-dxpq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 0.4,
              "comparator" : "<",
              "unit" : "% w/w",
              "system" : "http://unitsofmeasure.org",
              "code" : "%"
            },
            "component" : [
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "IMP",
                      "display" : "Impurity"
                    }
                  ]
                },
                "valueCodeableConcept" : {
                  "text" : "Impurity 1"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:fe6ca484-a755-9a0b-a074-b6ee0a907ff8",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "fe6ca484-a755-9a0b-a074-b6ee0a907ff8",
            "text" : // observationDegradation-imp1-3
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_fe6ca484-a755-9a0b-a074-b6ee0a907ff8\"> </a><p><b>Generated Narrative: Observation</b><a name=\"fe6ca484-a755-9a0b-a074-b6ee0a907ff8\"> </a><a name=\"hcfe6ca484-a755-9a0b-a074-b6ee0a907ff8\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;fe6ca484-a755-9a0b-a074-b6ee0a907ff8&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/d04e0f2a-6ee7-6c2e-1db8-7df394c927b8</p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: See on this page: Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: &lt;0.2 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 1 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/d04e0f2a-6ee7-6c2e-1db8-7df394c927b8"
            },
            "status" : "final",
            "code" : // ObservationDefinition/Impurities
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Impurities",
                  "display" : "Impurities"
                }
              ],
              "text" : "Impurities"
            },
            "subject" : {
              "reference" : "Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/substance-dxpq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 0.2,
              "comparator" : "<",
              "unit" : "% w/w",
              "system" : "http://unitsofmeasure.org",
              "code" : "%"
            },
            "component" : [
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "IMP",
                      "display" : "Impurity"
                    }
                  ]
                },
                "valueCodeableConcept" : {
                  "text" : "Impurity 1"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:02d9e6be-833c-2c6d-a64a-baa3935c959d",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "02d9e6be-833c-2c6d-a64a-baa3935c959d",
            "text" : // observationDegradation-imp1Second
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_02d9e6be-833c-2c6d-a64a-baa3935c959d\"> </a><p><b>Generated Narrative: Observation</b><a name=\"02d9e6be-833c-2c6d-a64a-baa3935c959d\"> </a><a name=\"hc02d9e6be-833c-2c6d-a64a-baa3935c959d\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;02d9e6be-833c-2c6d-a64a-baa3935c959d&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/d04e0f2a-6ee7-6c2e-1db8-7df394c927b8</p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: See on this page: Substance/6412c5d4-1b7d-8405-85dc-75dbaa300ea4</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: &lt;0.55 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 1 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/d04e0f2a-6ee7-6c2e-1db8-7df394c927b8"
            },
            "status" : "final",
            "code" : // ObservationDefinition/Impurities
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Impurities",
                  "display" : "Impurities"
                }
              ],
              "text" : "Impurities"
            },
            "subject" : {
              "reference" : "Substance/6412c5d4-1b7d-8405-85dc-75dbaa300ea4"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/actual-batch-substance-2
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 0.55,
              "comparator" : "<",
              "unit" : "% w/w",
              "system" : "http://unitsofmeasure.org",
              "code" : "%"
            },
            "component" : [
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "IMP",
                      "display" : "Impurity"
                    }
                  ]
                },
                "valueCodeableConcept" : {
                  "text" : "Impurity 1"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:da92c71f-a12a-1980-11a3-80e3d1852244",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "da92c71f-a12a-1980-11a3-80e3d1852244",
            "text" : // observationDegradation-imp2
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_da92c71f-a12a-1980-11a3-80e3d1852244\"> </a><p><b>Generated Narrative: Observation</b><a name=\"da92c71f-a12a-1980-11a3-80e3d1852244\"> </a><a name=\"hcda92c71f-a12a-1980-11a3-80e3d1852244\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;da92c71f-a12a-1980-11a3-80e3d1852244&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/d04e0f2a-6ee7-6c2e-1db8-7df394c927b8</p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: See on this page: Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: &lt;0.5 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 2 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/d04e0f2a-6ee7-6c2e-1db8-7df394c927b8"
            },
            "status" : "final",
            "code" : // ObservationDefinition/Impurities
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Impurities",
                  "display" : "Impurities"
                }
              ],
              "text" : "Impurities"
            },
            "subject" : {
              "reference" : "Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/substance-dxpq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 0.5,
              "comparator" : "<",
              "unit" : "% w/w",
              "system" : "http://unitsofmeasure.org",
              "code" : "%"
            },
            "component" : [
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "IMP",
                      "display" : "Impurity"
                    }
                  ]
                },
                "valueCodeableConcept" : {
                  "text" : "Impurity 2"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:8bf75da1-9221-66fe-6725-c64cb45a57e6",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "8bf75da1-9221-66fe-6725-c64cb45a57e6",
            "text" : // observationDegradation-imp2-2
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_8bf75da1-9221-66fe-6725-c64cb45a57e6\"> </a><p><b>Generated Narrative: Observation</b><a name=\"8bf75da1-9221-66fe-6725-c64cb45a57e6\"> </a><a name=\"hc8bf75da1-9221-66fe-6725-c64cb45a57e6\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;8bf75da1-9221-66fe-6725-c64cb45a57e6&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/d04e0f2a-6ee7-6c2e-1db8-7df394c927b8</p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: See on this page: Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: &lt;0.4 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 2 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/d04e0f2a-6ee7-6c2e-1db8-7df394c927b8"
            },
            "status" : "final",
            "code" : // ObservationDefinition/Impurities
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Impurities",
                  "display" : "Impurities"
                }
              ],
              "text" : "Impurities"
            },
            "subject" : {
              "reference" : "Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/substance-dxpq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 0.4,
              "comparator" : "<",
              "unit" : "% w/w",
              "system" : "http://unitsofmeasure.org",
              "code" : "%"
            },
            "component" : [
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "IMP",
                      "display" : "Impurity"
                    }
                  ]
                },
                "valueCodeableConcept" : {
                  "text" : "Impurity 2"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:31bfeff4-4a7d-3be5-878e-fb674d3d5487",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "31bfeff4-4a7d-3be5-878e-fb674d3d5487",
            "text" : // observationDegradation-imp2-3
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_31bfeff4-4a7d-3be5-878e-fb674d3d5487\"> </a><p><b>Generated Narrative: Observation</b><a name=\"31bfeff4-4a7d-3be5-878e-fb674d3d5487\"> </a><a name=\"hc31bfeff4-4a7d-3be5-878e-fb674d3d5487\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;31bfeff4-4a7d-3be5-878e-fb674d3d5487&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/d04e0f2a-6ee7-6c2e-1db8-7df394c927b8</p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: See on this page: Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: &lt;0.2 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 2 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/d04e0f2a-6ee7-6c2e-1db8-7df394c927b8"
            },
            "status" : "final",
            "code" : // ObservationDefinition/Impurities
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Impurities",
                  "display" : "Impurities"
                }
              ],
              "text" : "Impurities"
            },
            "subject" : {
              "reference" : "Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/substance-dxpq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 0.2,
              "comparator" : "<",
              "unit" : "% w/w",
              "system" : "http://unitsofmeasure.org",
              "code" : "%"
            },
            "component" : [
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "IMP",
                      "display" : "Impurity"
                    }
                  ]
                },
                "valueCodeableConcept" : {
                  "text" : "Impurity 2"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:da92c71f-a12a-1980-21a3-80e3d1852244",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "da92c71f-a12a-1980-21a3-80e3d1852244",
            "text" : // observationDegradation-imp2Second
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_da92c71f-a12a-1980-21a3-80e3d1852244\"> </a><p><b>Generated Narrative: Observation</b><a name=\"da92c71f-a12a-1980-21a3-80e3d1852244\"> </a><a name=\"hcda92c71f-a12a-1980-21a3-80e3d1852244\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;da92c71f-a12a-1980-21a3-80e3d1852244&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/d04e0f2a-6ee7-6c2e-1db8-7df394c927b8</p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: See on this page: Substance/6412c5d4-1b7d-8405-85dc-75dbaa300ea4</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: &lt;0.56 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 2 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/d04e0f2a-6ee7-6c2e-1db8-7df394c927b8"
            },
            "status" : "final",
            "code" : // ObservationDefinition/Impurities
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Impurities",
                  "display" : "Impurities"
                }
              ],
              "text" : "Impurities"
            },
            "subject" : {
              "reference" : "Substance/6412c5d4-1b7d-8405-85dc-75dbaa300ea4"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/actual-batch-substance-2
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 0.56,
              "comparator" : "<",
              "unit" : "% w/w",
              "system" : "http://unitsofmeasure.org",
              "code" : "%"
            },
            "component" : [
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "IMP",
                      "display" : "Impurity"
                    }
                  ]
                },
                "valueCodeableConcept" : {
                  "text" : "Impurity 2"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:732237a9-4b3b-27cc-99ca-6b913e622a29",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "732237a9-4b3b-27cc-99ca-6b913e622a29",
            "text" : // observationDegradation-imp3
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_732237a9-4b3b-27cc-99ca-6b913e622a29\"> </a><p><b>Generated Narrative: Observation</b><a name=\"732237a9-4b3b-27cc-99ca-6b913e622a29\"> </a><a name=\"hc732237a9-4b3b-27cc-99ca-6b913e622a29\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;732237a9-4b3b-27cc-99ca-6b913e622a29&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/d04e0f2a-6ee7-6c2e-1db8-7df394c927b8</p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: See on this page: Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: &lt;0.1 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 3 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/d04e0f2a-6ee7-6c2e-1db8-7df394c927b8"
            },
            "status" : "final",
            "code" : // ObservationDefinition/Impurities
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Impurities",
                  "display" : "Impurities"
                }
              ],
              "text" : "Impurities"
            },
            "subject" : {
              "reference" : "Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/substance-dxpq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 0.1,
              "comparator" : "<",
              "unit" : "% w/w",
              "system" : "http://unitsofmeasure.org",
              "code" : "%"
            },
            "component" : [
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "IMP",
                      "display" : "Impurity"
                    }
                  ]
                },
                "valueCodeableConcept" : {
                  "text" : "Impurity 3"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:732237a9-4b3b-27dc-99ca-6b913e622a29",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "732237a9-4b3b-27dc-99ca-6b913e622a29",
            "text" : // observationDegradation-imp3Second
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_732237a9-4b3b-27dc-99ca-6b913e622a29\"> </a><p><b>Generated Narrative: Observation</b><a name=\"732237a9-4b3b-27dc-99ca-6b913e622a29\"> </a><a name=\"hc732237a9-4b3b-27dc-99ca-6b913e622a29\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;732237a9-4b3b-27dc-99ca-6b913e622a29&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/d04e0f2a-6ee7-6c2e-1db8-7df394c927b8</p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: See on this page: Substance/6412c5d4-1b7d-8405-85dc-75dbaa300ea4</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: &lt;0.13 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 3 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/d04e0f2a-6ee7-6c2e-1db8-7df394c927b8"
            },
            "status" : "final",
            "code" : // ObservationDefinition/Impurities
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Impurities",
                  "display" : "Impurities"
                }
              ],
              "text" : "Impurities"
            },
            "subject" : {
              "reference" : "Substance/6412c5d4-1b7d-8405-85dc-75dbaa300ea4"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/actual-batch-substance-2
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 0.13,
              "comparator" : "<",
              "unit" : "% w/w",
              "system" : "http://unitsofmeasure.org",
              "code" : "%"
            },
            "component" : [
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "IMP",
                      "display" : "Impurity"
                    }
                  ]
                },
                "valueCodeableConcept" : {
                  "text" : "Impurity 3"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:52afbeb4-4958-a275-a0ca-d70b2b5240ec",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "52afbeb4-4958-a275-a0ca-d70b2b5240ec",
            "text" : // observationDegradation-imp3-2
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_52afbeb4-4958-a275-a0ca-d70b2b5240ec\"> </a><p><b>Generated Narrative: Observation</b><a name=\"52afbeb4-4958-a275-a0ca-d70b2b5240ec\"> </a><a name=\"hc52afbeb4-4958-a275-a0ca-d70b2b5240ec\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;52afbeb4-4958-a275-a0ca-d70b2b5240ec&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/d04e0f2a-6ee7-6c2e-1db8-7df394c927b8</p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: See on this page: Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: &lt;0.1 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 3 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/d04e0f2a-6ee7-6c2e-1db8-7df394c927b8"
            },
            "status" : "final",
            "code" : // ObservationDefinition/Impurities
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Impurities",
                  "display" : "Impurities"
                }
              ],
              "text" : "Impurities"
            },
            "subject" : {
              "reference" : "Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/substance-dxpq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 0.1,
              "comparator" : "<",
              "unit" : "% w/w",
              "system" : "http://unitsofmeasure.org",
              "code" : "%"
            },
            "component" : [
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "IMP",
                      "display" : "Impurity"
                    }
                  ]
                },
                "valueCodeableConcept" : {
                  "text" : "Impurity 3"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:7fc395b1-59e4-78be-0512-cf92133c0fac",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "7fc395b1-59e4-78be-0512-cf92133c0fac",
            "text" : // observationDegradation-imp3-3
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_7fc395b1-59e4-78be-0512-cf92133c0fac\"> </a><p><b>Generated Narrative: Observation</b><a name=\"7fc395b1-59e4-78be-0512-cf92133c0fac\"> </a><a name=\"hc7fc395b1-59e4-78be-0512-cf92133c0fac\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;7fc395b1-59e4-78be-0512-cf92133c0fac&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/d04e0f2a-6ee7-6c2e-1db8-7df394c927b8</p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: See on this page: Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: &lt;0.1 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 3 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/d04e0f2a-6ee7-6c2e-1db8-7df394c927b8"
            },
            "status" : "final",
            "code" : // ObservationDefinition/Impurities
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Impurities",
                  "display" : "Impurities"
                }
              ],
              "text" : "Impurities"
            },
            "subject" : {
              "reference" : "Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/substance-dxpq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 0.1,
              "comparator" : "<",
              "unit" : "% w/w",
              "system" : "http://unitsofmeasure.org",
              "code" : "%"
            },
            "component" : [
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "IMP",
                      "display" : "Impurity"
                    }
                  ]
                },
                "valueCodeableConcept" : {
                  "text" : "Impurity 3"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:10b80cbd-45d3-9be1-63b9-29f04b47376c",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "10b80cbd-45d3-9be1-63b9-29f04b47376c",
            "text" : // observationDegradation-imp-total
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_10b80cbd-45d3-9be1-63b9-29f04b47376c\"> </a><p><b>Generated Narrative: Observation</b><a name=\"10b80cbd-45d3-9be1-63b9-29f04b47376c\"> </a><a name=\"hc10b80cbd-45d3-9be1-63b9-29f04b47376c\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;10b80cbd-45d3-9be1-63b9-29f04b47376c&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/d04e0f2a-6ee7-6c2e-1db8-7df394c927b8</p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: See on this page: Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: &lt;0.02 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Total impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/d04e0f2a-6ee7-6c2e-1db8-7df394c927b8"
            },
            "status" : "final",
            "code" : // ObservationDefinition/Impurities
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Impurities",
                  "display" : "Impurities"
                }
              ],
              "text" : "Impurities"
            },
            "subject" : {
              "reference" : "Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/substance-dxpq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 0.02,
              "comparator" : "<",
              "unit" : "% w/w",
              "system" : "http://unitsofmeasure.org",
              "code" : "%"
            },
            "component" : [
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "IMP",
                      "display" : "Impurity"
                    }
                  ]
                },
                "valueCodeableConcept" : {
                  "text" : "Total impurities"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:84f015ac-9572-324f-8013-0b999cc95bbd",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "84f015ac-9572-324f-8013-0b999cc95bbd",
            "text" : // observationDegradation-imp-total-2
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_84f015ac-9572-324f-8013-0b999cc95bbd\"> </a><p><b>Generated Narrative: Observation</b><a name=\"84f015ac-9572-324f-8013-0b999cc95bbd\"> </a><a name=\"hc84f015ac-9572-324f-8013-0b999cc95bbd\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;84f015ac-9572-324f-8013-0b999cc95bbd&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/d04e0f2a-6ee7-6c2e-1db8-7df394c927b8</p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: See on this page: Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: &lt;0.02 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Total impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/d04e0f2a-6ee7-6c2e-1db8-7df394c927b8"
            },
            "status" : "final",
            "code" : // ObservationDefinition/Impurities
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Impurities",
                  "display" : "Impurities"
                }
              ],
              "text" : "Impurities"
            },
            "subject" : {
              "reference" : "Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/substance-dxpq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 0.02,
              "comparator" : "<",
              "unit" : "% w/w",
              "system" : "http://unitsofmeasure.org",
              "code" : "%"
            },
            "component" : [
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "IMP",
                      "display" : "Impurity"
                    }
                  ]
                },
                "valueCodeableConcept" : {
                  "text" : "Total impurities"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:987daeaa-4c2a-72b7-780f-4a9403163a3e",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "987daeaa-4c2a-72b7-780f-4a9403163a3e",
            "text" : // observationDegradation-imp-total-3
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_987daeaa-4c2a-72b7-780f-4a9403163a3e\"> </a><p><b>Generated Narrative: Observation</b><a name=\"987daeaa-4c2a-72b7-780f-4a9403163a3e\"> </a><a name=\"hc987daeaa-4c2a-72b7-780f-4a9403163a3e\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;987daeaa-4c2a-72b7-780f-4a9403163a3e&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/d04e0f2a-6ee7-6c2e-1db8-7df394c927b8</p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: See on this page: Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: &lt;0.02 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Total impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/d04e0f2a-6ee7-6c2e-1db8-7df394c927b8"
            },
            "status" : "final",
            "code" : // ObservationDefinition/Impurities
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Impurities",
                  "display" : "Impurities"
                }
              ],
              "text" : "Impurities"
            },
            "subject" : {
              "reference" : "Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/substance-dxpq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 0.02,
              "comparator" : "<",
              "unit" : "% w/w",
              "system" : "http://unitsofmeasure.org",
              "code" : "%"
            },
            "component" : [
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "IMP",
                      "display" : "Impurity"
                    }
                  ]
                },
                "valueCodeableConcept" : {
                  "text" : "Total impurities"
                }
              }
            ]
          }
        },
        //  could have the code of an imr substance, or could have an extension to point to it as a resource
        {
          "fullUrl" : "urn:uuid:10b80cbd-45d4-9be1-63b9-29f04b47376c",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "10b80cbd-45d4-9be1-63b9-29f04b47376c",
            "text" : // observationDegradation-imp-totalSecond
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_10b80cbd-45d4-9be1-63b9-29f04b47376c\"> </a><p><b>Generated Narrative: Observation</b><a name=\"10b80cbd-45d4-9be1-63b9-29f04b47376c\"> </a><a name=\"hc10b80cbd-45d4-9be1-63b9-29f04b47376c\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;10b80cbd-45d4-9be1-63b9-29f04b47376c&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/d04e0f2a-6ee7-6c2e-1db8-7df394c927b8</p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: See on this page: Substance/6412c5d4-1b7d-8405-85dc-75dbaa300ea4</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: &lt;0.18 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Total impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/d04e0f2a-6ee7-6c2e-1db8-7df394c927b8"
            },
            "status" : "final",
            "code" : // ObservationDefinition/Impurities
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Impurities",
                  "display" : "Impurities"
                }
              ],
              "text" : "Impurities"
            },
            "subject" : {
              "reference" : "Substance/6412c5d4-1b7d-8405-85dc-75dbaa300ea4"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/actual-batch-substance-2
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 0.18,
              "comparator" : "<",
              "unit" : "% w/w",
              "system" : "http://unitsofmeasure.org",
              "code" : "%"
            },
            "component" : [
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "IMP",
                      "display" : "Impurity"
                    }
                  ]
                },
                "valueCodeableConcept" : {
                  "text" : "Total impurities"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:ff26533d-88a8-7f18-a275-42dc1373a388",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "ff26533d-88a8-7f18-a275-42dc1373a388",
            "text" : // observationElemental
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_ff26533d-88a8-7f18-a275-42dc1373a388\"> </a><p><b>Generated Narrative: Observation</b><a name=\"ff26533d-88a8-7f18-a275-42dc1373a388\"> </a><a name=\"hcff26533d-88a8-7f18-a275-42dc1373a388\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;ff26533d-88a8-7f18-a275-42dc1373a388&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/0634020c-8729-99fc-7637-89799d7c445b</p><p><b>status</b>: final</p><p><b>code</b>: Elemental <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Elemental)</span></p><p><b>subject</b>: See on this page: Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: As, Cd, Hg, Pb: Not detected. Pd: &lt; 29 ppm</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity - Elemental <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/0634020c-8729-99fc-7637-89799d7c445b"
            },
            "status" : "final",
            "code" : // ObservationDefinition/Elemental
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Elemental",
                  "display" : "Elemental"
                }
              ]
            },
            "subject" : {
              "reference" : "Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/substance-dxpq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueString" : "As, Cd, Hg, Pb: Not detected. Pd: < 29 ppm",
            "component" : [
              // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "IMP",
                      "display" : "Impurity"
                    }
                  ]
                },
                "valueCodeableConcept" : {
                  "text" : "Impurity - Elemental"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:c99666d2-7962-9a71-58f6-7b2e5aa662f5",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "c99666d2-7962-9a71-58f6-7b2e5aa662f5",
            "text" : // observationElemental2
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_c99666d2-7962-9a71-58f6-7b2e5aa662f5\"> </a><p><b>Generated Narrative: Observation</b><a name=\"c99666d2-7962-9a71-58f6-7b2e5aa662f5\"> </a><a name=\"hcc99666d2-7962-9a71-58f6-7b2e5aa662f5\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;c99666d2-7962-9a71-58f6-7b2e5aa662f5&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/0634020c-8729-99fc-7637-89799d7c445b</p><p><b>status</b>: final</p><p><b>code</b>: Elemental <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Elemental)</span></p><p><b>subject</b>: See on this page: Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>dataAbsentReason</b>: Not tested <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.0.0/CodeSystem-data-absent-reason.html\">DataAbsentReason</a>#not-performed &quot;Not Performed&quot;)</span></p></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/0634020c-8729-99fc-7637-89799d7c445b"
            },
            "status" : "final",
            "code" : // ObservationDefinition/Elemental
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Elemental",
                  "display" : "Elemental"
                }
              ],
              "text" : "Elemental"
            },
            "subject" : {
              "reference" : "Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/substance-dxpq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "dataAbsentReason" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "coding" : [
                {
                  "system" : "http://terminology.hl7.org/CodeSystem/data-absent-reason",
                  "code" : "not-performed",
                  "display" : "Not Performed"
                }
              ],
              "text" : "Not tested"
            }
          }
        },
        {
          "fullUrl" : "urn:uuid:c18e21d3-7113-4d08-4ff3-0c9718596f64",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "c18e21d3-7113-4d08-4ff3-0c9718596f64",
            "text" : // observationElemental3
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_c18e21d3-7113-4d08-4ff3-0c9718596f64\"> </a><p><b>Generated Narrative: Observation</b><a name=\"c18e21d3-7113-4d08-4ff3-0c9718596f64\"> </a><a name=\"hcc18e21d3-7113-4d08-4ff3-0c9718596f64\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;c18e21d3-7113-4d08-4ff3-0c9718596f64&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/0634020c-8729-99fc-7637-89799d7c445b</p><p><b>status</b>: final</p><p><b>code</b>: Elemental <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Elemental)</span></p><p><b>subject</b>: See on this page: Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>dataAbsentReason</b>: Not tested <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.0.0/CodeSystem-data-absent-reason.html\">DataAbsentReason</a>#not-performed &quot;Not Performed&quot;)</span></p></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/0634020c-8729-99fc-7637-89799d7c445b"
            },
            "status" : "final",
            "code" : // ObservationDefinition/Elemental
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Elemental",
                  "display" : "Elemental"
                }
              ],
              "text" : "Elemental"
            },
            "subject" : {
              "reference" : "Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/substance-dxpq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "dataAbsentReason" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "coding" : [
                {
                  "system" : "http://terminology.hl7.org/CodeSystem/data-absent-reason",
                  "code" : "not-performed",
                  "display" : "Not Performed"
                }
              ],
              "text" : "Not tested"
            }
          }
        },
        {
          "fullUrl" : "urn:uuid:ff26533d-88a8-7f18-a275-52dc1373a388",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "ff26533d-88a8-7f18-a275-52dc1373a388",
            "text" : // observationElementalSecond
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_ff26533d-88a8-7f18-a275-52dc1373a388\"> </a><p><b>Generated Narrative: Observation</b><a name=\"ff26533d-88a8-7f18-a275-52dc1373a388\"> </a><a name=\"hcff26533d-88a8-7f18-a275-52dc1373a388\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;ff26533d-88a8-7f18-a275-52dc1373a388&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/0634020c-8729-99fc-7637-89799d7c445b</p><p><b>status</b>: final</p><p><b>code</b>: Elemental <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Elemental)</span></p><p><b>subject</b>: See on this page: Substance/6412c5d4-1b7d-8405-85dc-75dbaa300ea4</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: As, Cd, Hg, Pb: Not detected. Pd: &lt; 31 ppm</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity - Elemental <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/0634020c-8729-99fc-7637-89799d7c445b"
            },
            "status" : "final",
            "code" : // ObservationDefinition/Elemental
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Elemental",
                  "display" : "Elemental"
                }
              ]
            },
            "subject" : {
              "reference" : "Substance/6412c5d4-1b7d-8405-85dc-75dbaa300ea4"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/actual-batch-substance-2
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueString" : "As, Cd, Hg, Pb: Not detected. Pd: < 31 ppm",
            "component" : [
              // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "IMP",
                      "display" : "Impurity"
                    }
                  ]
                },
                "valueCodeableConcept" : {
                  "text" : "Impurity - Elemental"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:ff26533d-88b8-7f18-a275-42dc1373a388",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "ff26533d-88b8-7f18-a275-42dc1373a388",
            "text" : // observationAssignedPurity1
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_ff26533d-88b8-7f18-a275-42dc1373a388\"> </a><p><b>Generated Narrative: Observation</b><a name=\"ff26533d-88b8-7f18-a275-42dc1373a388\"> </a><a name=\"hcff26533d-88b8-7f18-a275-42dc1373a388\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;ff26533d-88b8-7f18-a275-42dc1373a388&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/0634020c-8729-99fc-7637-897a9d7c445b</p><p><b>status</b>: final</p><p><b>code</b>: Assigned Purity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#AssignedPurity)</span></p><p><b>subject</b>: See on this page: Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1</p><p><b>effective</b>: 2021-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 85.22 %</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity - Elemental <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/0634020c-8729-99fc-7637-897a9d7c445b"
            },
            "status" : "final",
            "code" : // ObservationDefinition/AssignedPurity
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "AssignedPurity",
                  "display" : "Assigned Purity"
                }
              ]
            },
            "subject" : {
              "reference" : "Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1"
            },
            "effectiveDateTime" : "2021-01-01T12:00:00Z",
            "performer" : [
              // Substance/substance-dxpq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 85.22,
              "unit" : "%"
            },
            "component" : [
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "IMP",
                      "display" : "Impurity"
                    }
                  ]
                },
                "valueCodeableConcept" : {
                  "text" : "Impurity - Elemental"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:ff26534d-88b8-7f18-a275-42dc1373a388",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "ff26534d-88b8-7f18-a275-42dc1373a388",
            "text" : // observationAssignedPurity2
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_ff26534d-88b8-7f18-a275-42dc1373a388\"> </a><p><b>Generated Narrative: Observation</b><a name=\"ff26534d-88b8-7f18-a275-42dc1373a388\"> </a><a name=\"hcff26534d-88b8-7f18-a275-42dc1373a388\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;ff26534d-88b8-7f18-a275-42dc1373a388&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/0634020c-8729-99fc-7637-897a9d7c445b</p><p><b>status</b>: final</p><p><b>code</b>: Assigned Purity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#AssignedPurity)</span></p><p><b>subject</b>: See on this page: Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1</p><p><b>effective</b>: 2022-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 85.33 %</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity - Elemental <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/0634020c-8729-99fc-7637-897a9d7c445b"
            },
            "status" : "final",
            "code" : // ObservationDefinition/AssignedPurity
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "AssignedPurity",
                  "display" : "Assigned Purity"
                }
              ]
            },
            "subject" : {
              "reference" : "Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1"
            },
            "effectiveDateTime" : "2022-01-01T12:00:00Z",
            "performer" : [
              // Substance/substance-dxpq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 85.33,
              "unit" : "%"
            },
            "component" : [
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "IMP",
                      "display" : "Impurity"
                    }
                  ]
                },
                "valueCodeableConcept" : {
                  "text" : "Impurity - Elemental"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:ff26544d-88b8-7f18-a275-42dc1373a388",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "ff26544d-88b8-7f18-a275-42dc1373a388",
            "text" : // observationAssignedPurity3
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_ff26544d-88b8-7f18-a275-42dc1373a388\"> </a><p><b>Generated Narrative: Observation</b><a name=\"ff26544d-88b8-7f18-a275-42dc1373a388\"> </a><a name=\"hcff26544d-88b8-7f18-a275-42dc1373a388\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;ff26544d-88b8-7f18-a275-42dc1373a388&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/0634020c-8729-99fc-7637-897a9d7c445b</p><p><b>status</b>: final</p><p><b>code</b>: Assigned Purity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#AssignedPurity)</span></p><p><b>subject</b>: See on this page: Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 85.44 %</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity - Elemental <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/0634020c-8729-99fc-7637-897a9d7c445b"
            },
            "status" : "final",
            "code" : // ObservationDefinition/AssignedPurity
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "AssignedPurity",
                  "display" : "Assigned Purity"
                }
              ]
            },
            "subject" : {
              "reference" : "Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/substance-dxpq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 85.44,
              "unit" : "%"
            },
            "component" : [
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "IMP",
                      "display" : "Impurity"
                    }
                  ]
                },
                "valueCodeableConcept" : {
                  "text" : "Impurity - Elemental"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:ff36533d-88b8-7f18-a275-42dc1373a388",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "ff36533d-88b8-7f18-a275-42dc1373a388",
            "text" : // observationAssignedPurity1second
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_ff36533d-88b8-7f18-a275-42dc1373a388\"> </a><p><b>Generated Narrative: Observation</b><a name=\"ff36533d-88b8-7f18-a275-42dc1373a388\"> </a><a name=\"hcff36533d-88b8-7f18-a275-42dc1373a388\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;ff36533d-88b8-7f18-a275-42dc1373a388&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/0634020c-8729-99fc-7637-897a9d7c445b</p><p><b>status</b>: final</p><p><b>code</b>: Assigned Purity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#AssignedPurity)</span></p><p><b>subject</b>: See on this page: Substance/6412c5d4-1b7d-8405-85dc-75dbaa300ea4</p><p><b>effective</b>: 2021-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 75.22 %</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity - Elemental <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/0634020c-8729-99fc-7637-897a9d7c445b"
            },
            "status" : "final",
            "code" : // ObservationDefinition/AssignedPurity
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "AssignedPurity",
                  "display" : "Assigned Purity"
                }
              ]
            },
            "subject" : {
              "reference" : "Substance/6412c5d4-1b7d-8405-85dc-75dbaa300ea4"
            },
            "effectiveDateTime" : "2021-01-01T12:00:00Z",
            "performer" : [
              // Substance/actual-batch-substance-2
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 75.22,
              "unit" : "%"
            },
            "component" : [
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "IMP",
                      "display" : "Impurity"
                    }
                  ]
                },
                "valueCodeableConcept" : {
                  "text" : "Impurity - Elemental"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:f8160692-a7a8-3fa6-9f35-e7df35f51ac0",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "f8160692-a7a8-3fa6-9f35-e7df35f51ac0",
            "text" : // observationSolvents-sol1
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_f8160692-a7a8-3fa6-9f35-e7df35f51ac0\"> </a><p><b>Generated Narrative: Observation</b><a name=\"f8160692-a7a8-3fa6-9f35-e7df35f51ac0\"> </a><a name=\"hcf8160692-a7a8-3fa6-9f35-e7df35f51ac0\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;f8160692-a7a8-3fa6-9f35-e7df35f51ac0&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/2daba8ca-211f-4f4b-4028-16c30fe22ee8</p><p><b>status</b>: final</p><p><b>code</b>: Residual solvents <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SOL)</span></p><p><b>subject</b>: See on this page: Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.1 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Solvent <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SOLV)</span></td><td>Solvent 1 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/2daba8ca-211f-4f4b-4028-16c30fe22ee8"
            },
            "status" : "final",
            "code" : // ObservationDefinition/Solvents
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "SOL",
                  "display" : "Residual solvents"
                }
              ]
            },
            "subject" : {
              "reference" : "Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/substance-dxpq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 0.1,
              "unit" : "% w/w",
              "system" : "http://unitsofmeasure.org",
              "code" : "%"
            },
            "component" : [
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "SOLV",
                      "display" : "Solvent"
                    }
                  ]
                },
                "valueCodeableConcept" : {
                  "text" : "Solvent 1"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:a531aee9-4c21-06af-352c-a3615b5d957e",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "a531aee9-4c21-06af-352c-a3615b5d957e",
            "text" : // observationSolvents-sol1-2
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_a531aee9-4c21-06af-352c-a3615b5d957e\"> </a><p><b>Generated Narrative: Observation</b><a name=\"a531aee9-4c21-06af-352c-a3615b5d957e\"> </a><a name=\"hca531aee9-4c21-06af-352c-a3615b5d957e\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;a531aee9-4c21-06af-352c-a3615b5d957e&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/2daba8ca-211f-4f4b-4028-16c30fe22ee8</p><p><b>status</b>: final</p><p><b>code</b>: Residual solvents <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SOL)</span></p><p><b>subject</b>: See on this page: Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.1 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Solvent <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SOLV)</span></td><td>Solvent 1 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/2daba8ca-211f-4f4b-4028-16c30fe22ee8"
            },
            "status" : "final",
            "code" : // ObservationDefinition/Solvents
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "SOL",
                  "display" : "Residual solvents"
                }
              ]
            },
            "subject" : {
              "reference" : "Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/substance-dxpq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 0.1,
              "unit" : "% w/w",
              "system" : "http://unitsofmeasure.org",
              "code" : "%"
            },
            "component" : [
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "SOLV",
                      "display" : "Solvent"
                    }
                  ]
                },
                "valueCodeableConcept" : {
                  "text" : "Solvent 1"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:033ce81d-5f0d-7a3e-93d3-fc64e122a1fd",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "033ce81d-5f0d-7a3e-93d3-fc64e122a1fd",
            "text" : // observationSolvents-sol1-3
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_033ce81d-5f0d-7a3e-93d3-fc64e122a1fd\"> </a><p><b>Generated Narrative: Observation</b><a name=\"033ce81d-5f0d-7a3e-93d3-fc64e122a1fd\"> </a><a name=\"hc033ce81d-5f0d-7a3e-93d3-fc64e122a1fd\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;033ce81d-5f0d-7a3e-93d3-fc64e122a1fd&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/2daba8ca-211f-4f4b-4028-16c30fe22ee8</p><p><b>status</b>: final</p><p><b>code</b>: Residual solvents <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SOL)</span></p><p><b>subject</b>: See on this page: Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.1 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Solvent <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SOLV)</span></td><td>Solvent 1 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/2daba8ca-211f-4f4b-4028-16c30fe22ee8"
            },
            "status" : "final",
            "code" : // ObservationDefinition/Solvents
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "SOL",
                  "display" : "Residual solvents"
                }
              ]
            },
            "subject" : {
              "reference" : "Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/substance-dxpq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 0.1,
              "unit" : "% w/w",
              "system" : "http://unitsofmeasure.org",
              "code" : "%"
            },
            "component" : [
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "SOLV",
                      "display" : "Solvent"
                    }
                  ]
                },
                "valueCodeableConcept" : {
                  "text" : "Solvent 1"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:f8160692-b7a8-3fa6-9f35-e7df35f51ac0",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "f8160692-b7a8-3fa6-9f35-e7df35f51ac0",
            "text" : // observationSolvents-sol1Second
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_f8160692-b7a8-3fa6-9f35-e7df35f51ac0\"> </a><p><b>Generated Narrative: Observation</b><a name=\"f8160692-b7a8-3fa6-9f35-e7df35f51ac0\"> </a><a name=\"hcf8160692-b7a8-3fa6-9f35-e7df35f51ac0\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;f8160692-b7a8-3fa6-9f35-e7df35f51ac0&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/2daba8ca-211f-4f4b-4028-16c30fe22ee8</p><p><b>status</b>: final</p><p><b>code</b>: Residual solvents <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SOL)</span></p><p><b>subject</b>: See on this page: Substance/6412c5d4-1b7d-8405-85dc-75dbaa300ea4</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.13 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Solvent <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SOLV)</span></td><td>Solvent 1 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/2daba8ca-211f-4f4b-4028-16c30fe22ee8"
            },
            "status" : "final",
            "code" : // ObservationDefinition/Solvents
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "SOL",
                  "display" : "Residual solvents"
                }
              ]
            },
            "subject" : {
              "reference" : "Substance/6412c5d4-1b7d-8405-85dc-75dbaa300ea4"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/actual-batch-substance-2
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 0.13,
              "unit" : "% w/w",
              "system" : "http://unitsofmeasure.org",
              "code" : "%"
            },
            "component" : [
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "SOLV",
                      "display" : "Solvent"
                    }
                  ]
                },
                "valueCodeableConcept" : {
                  "text" : "Solvent 1"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:ba8a182e-8571-6cbd-047b-612735d599d2",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "ba8a182e-8571-6cbd-047b-612735d599d2",
            "text" : // observationSolvents-sol2
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_ba8a182e-8571-6cbd-047b-612735d599d2\"> </a><p><b>Generated Narrative: Observation</b><a name=\"ba8a182e-8571-6cbd-047b-612735d599d2\"> </a><a name=\"hcba8a182e-8571-6cbd-047b-612735d599d2\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;ba8a182e-8571-6cbd-047b-612735d599d2&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/2daba8ca-211f-4f4b-4028-16c30fe22ee8</p><p><b>status</b>: final</p><p><b>code</b>: Residual solvents <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SOL)</span></p><p><b>subject</b>: See on this page: Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 1.4 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Solvent <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SOLV)</span></td><td>Solvent 2 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/2daba8ca-211f-4f4b-4028-16c30fe22ee8"
            },
            "status" : "final",
            "code" : // ObservationDefinition/Solvents
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "SOL",
                  "display" : "Residual solvents"
                }
              ]
            },
            "subject" : {
              "reference" : "Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/substance-dxpq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 1.4,
              "unit" : "% w/w",
              "system" : "http://unitsofmeasure.org",
              "code" : "%"
            },
            "component" : [
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "SOLV",
                      "display" : "Solvent"
                    }
                  ]
                },
                "valueCodeableConcept" : {
                  "text" : "Solvent 2"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:0b5b94cc-7a1a-4ada-66c7-954ceb528d67",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "0b5b94cc-7a1a-4ada-66c7-954ceb528d67",
            "text" : // observationSolvents-sol2-2
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_0b5b94cc-7a1a-4ada-66c7-954ceb528d67\"> </a><p><b>Generated Narrative: Observation</b><a name=\"0b5b94cc-7a1a-4ada-66c7-954ceb528d67\"> </a><a name=\"hc0b5b94cc-7a1a-4ada-66c7-954ceb528d67\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;0b5b94cc-7a1a-4ada-66c7-954ceb528d67&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/2daba8ca-211f-4f4b-4028-16c30fe22ee8</p><p><b>status</b>: final</p><p><b>code</b>: Residual solvents <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SOL)</span></p><p><b>subject</b>: See on this page: Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 1.5 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Solvent <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SOLV)</span></td><td>Solvent 2 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/2daba8ca-211f-4f4b-4028-16c30fe22ee8"
            },
            "status" : "final",
            "code" : // ObservationDefinition/Solvents
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "SOL",
                  "display" : "Residual solvents"
                }
              ]
            },
            "subject" : {
              "reference" : "Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/substance-dxpq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 1.5,
              "unit" : "% w/w",
              "system" : "http://unitsofmeasure.org",
              "code" : "%"
            },
            "component" : [
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "SOLV",
                      "display" : "Solvent"
                    }
                  ]
                },
                "valueCodeableConcept" : {
                  "text" : "Solvent 2"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:6afaacee-11a6-58b2-47df-5f79722c66ac",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "6afaacee-11a6-58b2-47df-5f79722c66ac",
            "text" : // observationSolvents-sol2-3
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_6afaacee-11a6-58b2-47df-5f79722c66ac\"> </a><p><b>Generated Narrative: Observation</b><a name=\"6afaacee-11a6-58b2-47df-5f79722c66ac\"> </a><a name=\"hc6afaacee-11a6-58b2-47df-5f79722c66ac\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;6afaacee-11a6-58b2-47df-5f79722c66ac&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/2daba8ca-211f-4f4b-4028-16c30fe22ee8</p><p><b>status</b>: final</p><p><b>code</b>: Residual solvents <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SOL)</span></p><p><b>subject</b>: See on this page: Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 1.2 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Solvent <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SOLV)</span></td><td>Solvent 2 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/2daba8ca-211f-4f4b-4028-16c30fe22ee8"
            },
            "status" : "final",
            "code" : // ObservationDefinition/Solvents
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "SOL",
                  "display" : "Residual solvents"
                }
              ]
            },
            "subject" : {
              "reference" : "Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/substance-dxpq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 1.2,
              "unit" : "% w/w",
              "system" : "http://unitsofmeasure.org",
              "code" : "%"
            },
            "component" : [
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "SOLV",
                      "display" : "Solvent"
                    }
                  ]
                },
                "valueCodeableConcept" : {
                  "text" : "Solvent 2"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:ba8a182e-9571-6cbd-047b-612735d599d2",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "ba8a182e-9571-6cbd-047b-612735d599d2",
            "text" : // observationSolvents-sol2Second
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_ba8a182e-9571-6cbd-047b-612735d599d2\"> </a><p><b>Generated Narrative: Observation</b><a name=\"ba8a182e-9571-6cbd-047b-612735d599d2\"> </a><a name=\"hcba8a182e-9571-6cbd-047b-612735d599d2\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;ba8a182e-9571-6cbd-047b-612735d599d2&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/2daba8ca-211f-4f4b-4028-16c30fe22ee8</p><p><b>status</b>: final</p><p><b>code</b>: Residual solvents <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SOL)</span></p><p><b>subject</b>: See on this page: Substance/6412c5d4-1b7d-8405-85dc-75dbaa300ea4</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 1.43 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Solvent <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SOLV)</span></td><td>Solvent 2 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/2daba8ca-211f-4f4b-4028-16c30fe22ee8"
            },
            "status" : "final",
            "code" : // ObservationDefinition/Solvents
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "SOL",
                  "display" : "Residual solvents"
                }
              ]
            },
            "subject" : {
              "reference" : "Substance/6412c5d4-1b7d-8405-85dc-75dbaa300ea4"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/actual-batch-substance-2
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 1.43,
              "unit" : "% w/w",
              "system" : "http://unitsofmeasure.org",
              "code" : "%"
            },
            "component" : [
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "SOLV",
                      "display" : "Solvent"
                    }
                  ]
                },
                "valueCodeableConcept" : {
                  "text" : "Solvent 2"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:c2644a86-1684-286e-00e2-dcaf907a8970",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "c2644a86-1684-286e-00e2-dcaf907a8970",
            "text" : // observationWater
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_c2644a86-1684-286e-00e2-dcaf907a8970\"> </a><p><b>Generated Narrative: Observation</b><a name=\"c2644a86-1684-286e-00e2-dcaf907a8970\"> </a><a name=\"hcc2644a86-1684-286e-00e2-dcaf907a8970\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;c2644a86-1684-286e-00e2-dcaf907a8970&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/17b322fe-53ea-6c1f-521b-3b148ac05eb4</p><p><b>status</b>: final</p><p><b>code</b>: Water Content <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#WaterContent)</span></p><p><b>subject</b>: See on this page: Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.8 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/17b322fe-53ea-6c1f-521b-3b148ac05eb4"
            },
            "status" : "final",
            "code" : // ObservationDefinition/Water
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "WaterContent",
                  "display" : "Water Content"
                }
              ],
              "text" : "Water Content"
            },
            "subject" : {
              "reference" : "Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/substance-dxpq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 0.8,
              "unit" : "% w/w",
              "system" : "http://unitsofmeasure.org",
              "code" : "%"
            }
          }
        },
        {
          "fullUrl" : "urn:uuid:cb5f6872-6eeb-727a-7c33-f2c438581a1c",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "cb5f6872-6eeb-727a-7c33-f2c438581a1c",
            "text" : // observationWater2
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_cb5f6872-6eeb-727a-7c33-f2c438581a1c\"> </a><p><b>Generated Narrative: Observation</b><a name=\"cb5f6872-6eeb-727a-7c33-f2c438581a1c\"> </a><a name=\"hccb5f6872-6eeb-727a-7c33-f2c438581a1c\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;cb5f6872-6eeb-727a-7c33-f2c438581a1c&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/17b322fe-53ea-6c1f-521b-3b148ac05eb4</p><p><b>status</b>: final</p><p><b>code</b>: Water Content <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#WaterContent)</span></p><p><b>subject</b>: See on this page: Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.8 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/17b322fe-53ea-6c1f-521b-3b148ac05eb4"
            },
            "status" : "final",
            "code" : // ObservationDefinition/Water
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "WaterContent",
                  "display" : "Water Content"
                }
              ],
              "text" : "Water Content"
            },
            "subject" : {
              "reference" : "Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/substance-dxpq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 0.8,
              "unit" : "% w/w",
              "system" : "http://unitsofmeasure.org",
              "code" : "%"
            }
          }
        },
        {
          "fullUrl" : "urn:uuid:7faaf980-7c10-7b9a-9572-1bacd485824e",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "7faaf980-7c10-7b9a-9572-1bacd485824e",
            "text" : // observationWater3
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_7faaf980-7c10-7b9a-9572-1bacd485824e\"> </a><p><b>Generated Narrative: Observation</b><a name=\"7faaf980-7c10-7b9a-9572-1bacd485824e\"> </a><a name=\"hc7faaf980-7c10-7b9a-9572-1bacd485824e\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;7faaf980-7c10-7b9a-9572-1bacd485824e&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/17b322fe-53ea-6c1f-521b-3b148ac05eb4</p><p><b>status</b>: final</p><p><b>code</b>: Water Content <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#WaterContent)</span></p><p><b>subject</b>: See on this page: Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.8 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/17b322fe-53ea-6c1f-521b-3b148ac05eb4"
            },
            "status" : "final",
            "code" : // ObservationDefinition/Water
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "WaterContent",
                  "display" : "Water Content"
                }
              ],
              "text" : "Water Content"
            },
            "subject" : {
              "reference" : "Substance/87ef899b-14dd-26b7-7416-7ec1d01b62a1"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/substance-dxpq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 0.8,
              "unit" : "% w/w",
              "system" : "http://unitsofmeasure.org",
              "code" : "%"
            }
          }
        },
        {
          "fullUrl" : "urn:uuid:c2644a86-1685-286e-00e2-dcaf907a8970",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "c2644a86-1685-286e-00e2-dcaf907a8970",
            "text" : // observationWaterSecond
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_c2644a86-1685-286e-00e2-dcaf907a8970\"> </a><p><b>Generated Narrative: Observation</b><a name=\"c2644a86-1685-286e-00e2-dcaf907a8970\"> </a><a name=\"hcc2644a86-1685-286e-00e2-dcaf907a8970\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;c2644a86-1685-286e-00e2-dcaf907a8970&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/17b322fe-53ea-6c1f-521b-3b148ac05eb4</p><p><b>status</b>: final</p><p><b>code</b>: Water Content <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#WaterContent)</span></p><p><b>subject</b>: See on this page: Substance/6412c5d4-1b7d-8405-85dc-75dbaa300ea4</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.79 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/17b322fe-53ea-6c1f-521b-3b148ac05eb4"
            },
            "status" : "final",
            "code" : // ObservationDefinition/Water
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "WaterContent",
                  "display" : "Water Content"
                }
              ],
              "text" : "Water Content"
            },
            "subject" : {
              "reference" : "Substance/6412c5d4-1b7d-8405-85dc-75dbaa300ea4"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/actual-batch-substance-2
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 0.79,
              "unit" : "% w/w",
              "system" : "http://unitsofmeasure.org",
              "code" : "%"
            }
          }
        }
      ]
    }