Pharmaceutical Quality (Industry)
1.0.0 - STU1

Pharmaceutical Quality (Industry), published by HL7 International / Biomedical Research and Regulation. This guide is not an authorized publication; it is the continuous build for version 1.0.0 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/uv-dx-pq/ and changes regularly. See the Directory of published versions

## : Example: Bundle – Stability, product - JSON Representation

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    //  Product Stability Study
    {
      "resourceType" : "Bundle",
      "id" : "bundle-drug-stability-pq-ex1-prod",
      "meta" : //    <id value="product-stability-study"/>
      {
        "profile" : [
          🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Bundle-drug-stability-pq"
        ]
      },
      "type" : "collection",
      "entry" : [
        //  Section 11 - Stability Study - Results
        {
          "fullUrl" : "urn:uuid:6f4a3311-92c5-2b4a-533e-76341e414c63",
          "resource" : {
            "resourceType" : "DiagnosticReport",
            "id" : "diagnosticreport-analysis-drug-pq-stability-prod",
            "meta" : //  <id value="studyResultsReport"/>
            {
              "profile" : [
                🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/DiagnosticReport-analysis-drug-pq"
              ]
            },
            "text" : {
              "status" : "extensions",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"DiagnosticReport_diagnosticreport-analysis-drug-pq-stability-prod\"> </a><p><b>Generated Narrative: DiagnosticReport</b><a name=\"diagnosticreport-analysis-drug-pq-stability-prod\"> </a><a name=\"hcdiagnosticreport-analysis-drug-pq-stability-prod\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource DiagnosticReport &quot;diagnosticreport-analysis-drug-pq-stability-prod&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-DiagnosticReport-analysis-drug-pq.html\">DiagnosticReport - Analysis Drug PQ</a></p></div><p><b>Triggered by</b>: See on this page: PlanDefinition/c96cb248-1408-79fc-1f47-b17a6b2e4b54</p><p><b>Extension - Statistical Model PQ</b>: information about statistical model utilized to interpret stability study results <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>Extension - Container Orientation PQ</b>: Horizontal <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-container-orientation.html\">Container Orientation Codes</a>#horizontal &quot;horizontal&quot;)</span></p><p><b>identifier</b>: <code>https://eudract.europa.eu/example/identifier</code>/ABC1234</p><p><b>status</b>: final</p><p><b>code</b>: Stability Study Report - 18 months <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-report-type.html\">Pharmaceutical Report Type Codes</a>#Stability Study Report - 18 months)</span></p><p><b>effective</b>: 2020-12</p><p><b>performer</b>: See on this page: Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</p><p><b>result</b>: </p><ul><li>See on this page: Observation/6fabbf78-9678-8030-485f-b149956308d5</li><li>See on this page: Observation/74535cc6-5232-5ab5-81cf-167a480795e5</li><li>See on this page: Observation/8bf75da1-9221-66fe-6725-c64cb45a57e6</li><li>See on this page: Observation/e803ad6d-0cb3-87dd-6af1-4b88c654a47c</li><li>See on this page: Observation/3519f84a-2889-90a0-a6b7-ff2f1be66a73</li><li>See on this page: Observation/2ef362f1-0b65-3578-7f06-fbd74a24694a</li><li>See on this page: Observation/72e0640b-094b-909e-5268-3dee92af4bbd</li></ul><p><b>conclusion</b>: The samples have been assessed and the conclusion is that the shelf life can be 18 months.</p></div>"
            },
            "extension" : [
              {
                "url" : "http://hl7.org/fhir/StructureDefinition/workflow-triggeredBy",
                "valueReference" : {
                  "reference" : "PlanDefinition/c96cb248-1408-79fc-1f47-b17a6b2e4b54"
                }
              },
              // PlanDefinition/plandefinition-drug-pq-ex5-stability-study-protocol
              {
                "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-statistical-model-pq",
                "valueCodeableConcept" : {
                  "text" : "information about statistical model utilized to interpret stability study results"
                }
              },
              //  Want to use studyDesign, but problem is that this is CodeableConcept, which allows text. However when you use text, you then
                                have no place to put a context. Ideally this would be a code/code pair.
                                Code says "statistical model", code (or text) then says what it is
              {
                "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-container-orientation-pq",
                "valueCodeableConcept" : {
                  "coding" : [
                    {
                      "system" : "http://terminology.hl7.org/CodeSystem/container-orientation",
                      "code" : "horizontal",
                      "display" : "horizontal"
                    }
                  ],
                  "text" : "Horizontal"
                }
              }
            ],
            "identifier" : [
              //  Considered ObservatioDefinition.usageContext
              {
                "system" : "https://eudract.europa.eu/example/identifier",
                "value" : "ABC1234"
              }
            ],
            "status" : "final",
            "code" : {
              "coding" : [
                {
                  "system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-report-type",
                  "code" : "Stability Study Report - 18 months",
                  "display" : "Stability Study Report - 18 months"
                }
              ]
            },
            "effectiveDateTime" : "2020-12",
            "_effectiveDateTime" : {
              "extension" : [
                //  start of stability test
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-time-point-description-pq",
                  "valueCodeableConcept" : {
                    "coding" : [
                      {
                        "system" : "http://terminology.hl7.org/CodeSystem/time-point-description",
                        "code" : "Delayed Start Code",
                        "display" : "Delayed Start Code"
                      }
                    ],
                    "text" : "Refrigerated delayed testing"
                  }
                }
              ]
            },
            "performer" : [
              {
                "reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
              }
            ],
            "result" : [
              // Organization/tester
              {
                "reference" : "Observation/6fabbf78-9678-8030-485f-b149956308d5"
              },
              // Observation/observation-test-result-longterm25c-initial-1
              {
                "reference" : "Observation/74535cc6-5232-5ab5-81cf-167a480795e5"
              },
              // Observation/LongTerm25C-initial-2
              {
                "reference" : "Observation/8bf75da1-9221-66fe-6725-c64cb45a57e6"
              },
              // Observation/LongTerm25C-initial-3
              {
                "reference" : "Observation/e803ad6d-0cb3-87dd-6af1-4b88c654a47c"
              },
              // Observation/LongTerm25C-18m-1
              {
                "reference" : "Observation/3519f84a-2889-90a0-a6b7-ff2f1be66a73"
              },
              // Observation/LongTerm25C-18m-2
              {
                "reference" : "Observation/2ef362f1-0b65-3578-7f06-fbd74a24694a"
              },
              // Observation/LongTerm25C-18m-3
              {
                "reference" : "Observation/72e0640b-094b-909e-5268-3dee92af4bbd"
              }
            ],
            "conclusion" : "The samples have been assessed and the conclusion is that the shelf life can be 18 months."
          }
        },
        // Observation/Accelerated40C-3-1
        //  skipping middle months
        //  Accelerated
        //  skipping rest of Accelerated
        {
          "fullUrl" : "urn:uuid:c96cb248-1408-79fc-1f47-b17a6b2e4b54",
          "resource" : //  Section 11 - Stability Study - Protocol
          //  end of accelerated
          {
            "resourceType" : "PlanDefinition",
            "id" : "c96cb248-1408-79fc-1f47-b17a6b2e4b54",
            "meta" : // <id value="stabilityStudyProtocol"/>
            // id value="plandefinition-stability-study-protocol-dxpq-ex1"/
            // plandefinition-drug-pq-ex5-stability-study-protocol
            {
              "profile" : [
                🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/PlanDefinition-drug-pq"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"PlanDefinition_c96cb248-1408-79fc-1f47-b17a6b2e4b54\"> </a><p><b>Generated Narrative: PlanDefinition</b><a name=\"c96cb248-1408-79fc-1f47-b17a6b2e4b54\"> </a><a name=\"hcc96cb248-1408-79fc-1f47-b17a6b2e4b54\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource PlanDefinition &quot;c96cb248-1408-79fc-1f47-b17a6b2e4b54&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-PlanDefinition-drug-pq.html\">PlanDefinition - Drug PQ</a></p></div><p><b>url</b>: <code>http://example-server.com/fhir/PlanDefinition/c96cb248-1408-79fc-1f47-b17a6b2e4b54</code></p><p><b>title</b>: Stability Monitoring Program</p><p><b>type</b>: Stability Study Protocol <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-plan-type.html\">Pharmaceutical Plan Type Codes</a>#1244588)</span></p><p><b>status</b>: active</p><p><b>subject</b>: See on this page: MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5</p><p><b>description</b>: Narrative description of Stability Study</p><blockquote><p><b>action</b></p><p><b>title</b>: Stability Test Protocol for Long-term and Accelerated Storage of Stelbat Tablets, 20 mg</p><blockquote><p><b>action</b></p><p><b>title</b>: Long-Term</p><p><b>description</b>: 25°C/60% RH</p><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote></blockquote><blockquote><p><b>action</b></p><p><b>title</b>: Accelerated</p><p><b>description</b>: 40°C/75% RH</p><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote></blockquote></blockquote></div>"
            },
            "url" : "http://example-server.com/fhir/PlanDefinition/c96cb248-1408-79fc-1f47-b17a6b2e4b54",
            "title" : "Stability Monitoring Program",
            "type" : // http://example-server.com/fhir/PlanDefinition/c96cb248-1408-79fc-1f47-b17a6b2e4b54
            //             Added type (8/22/2023)
            {
              "coding" : [
                {
                  "system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-plan-type",
                  "code" : "1244588",
                  "display" : "Stability Study Protocol"
                }
              ]
            },
            "status" : "active",
            "subjectReference" : {
              "reference" : "MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"
            },
            "description" : "Narrative description of Stability Study",
            "action" : [
              // MedicinalProductDefinition/medicinalproductdefinition-drug-product-pq-ex1
              {
                "title" : "Stability Test Protocol for Long-term and Accelerated Storage of Stelbat Tablets, 20 mg",
                "action" : [
                  //  this is then entire thing
                  {
                    "title" : "Long-Term",
                    "description" : "25°C/60% RH",
                    "action" : [
                      //  TODO add codes here for the different levels?
                      {
                        "title" : "Initial",
                        "timingTiming" : //  0 months
                        {
                          "repeat" : {
                            "boundsRange" : {
                              "low" : {
                                "value" : 0,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              },
                              "high" : {
                                "value" : 0,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              }
                            },
                            "frequency" : 1
                          }
                        },
                        "action" : [
                          {
                            "title" : "XYZ",
                            "definitionCanonical" : "http://example-server.com/fhir/ActivityDefinition/4bfe1ee8-91ed-5c1b-3045-c749bb9d1d90"
                          }
                        ]
                      },
                      //  the categories to do at this step
                      //  Long term
                      // ActivityDefinition/activitydefinition-test-drug-pq-ex1
                      {
                        "title" : "3",
                        "timingTiming" : {
                          "repeat" : {
                            "boundsRange" : {
                              "low" : {
                                "value" : 3,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              },
                              "high" : {
                                "value" : 3,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              }
                            },
                            "frequency" : 1
                          }
                        },
                        "action" : [
                          {
                            "title" : "X",
                            "definitionCanonical" : "http://example-server.com/fhir/ActivityDefinition/610ca25c-6126-6117-8d4d-9458ccc33ce2"
                          }
                        ]
                      },
                      // ActivityDefinition/activitydefinition-stability-test-dxpq-ex1
                      {
                        "title" : "6",
                        "timingTiming" : {
                          "repeat" : {
                            "boundsRange" : {
                              "low" : {
                                "value" : 6,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              },
                              "high" : {
                                "value" : 6,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              }
                            },
                            "frequency" : 1
                          }
                        },
                        "action" : [
                          {
                            "title" : "X",
                            "definitionCanonical" : "http://example-server.com/fhir/ActivityDefinition/d99c1b63-2d32-4887-8157-525cc8ae4732"
                          }
                        ]
                      },
                      // ActivityDefinition/activityLongTerm25X-6
                      {
                        "title" : "9",
                        "timingTiming" : {
                          "repeat" : {
                            "boundsRange" : {
                              "low" : {
                                "value" : 9,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              },
                              "high" : {
                                "value" : 9,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              }
                            },
                            "frequency" : 1
                          }
                        },
                        "action" : [
                          {
                            "title" : "X",
                            "definitionCanonical" : "http://example-server.com/fhir/ActivityDefinition/38704856-0acf-95f0-000f-a933b6862fa0"
                          }
                        ]
                      },
                      // ActivityDefinition/activityLongTerm25X-9
                      {
                        "title" : "12",
                        "timingTiming" : {
                          "repeat" : {
                            "boundsRange" : {
                              "low" : {
                                "value" : 12,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              },
                              "high" : {
                                "value" : 12,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              }
                            },
                            "frequency" : 1
                          }
                        },
                        "action" : [
                          {
                            "title" : "XY",
                            "definitionCanonical" : "http://example-server.com/fhir/ActivityDefinition/f19a68b0-4ba1-7288-635e-12783035935b"
                          }
                        ]
                      },
                      // ActivityDefinition/activityLongTerm25XY-12
                      {
                        "title" : "18",
                        "timingTiming" : {
                          "repeat" : {
                            "boundsRange" : {
                              "low" : {
                                "value" : 18,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              },
                              "high" : {
                                "value" : 18,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              }
                            },
                            "frequency" : 1
                          }
                        },
                        "action" : [
                          {
                            "title" : "XY",
                            "definitionCanonical" : "http://example-server.com/fhir/ActivityDefinition/ce2df6ab-5087-435c-35cb-a84572e756a2"
                          }
                        ]
                      },
                      // ActivityDefinition/activityLongTerm25XY-18
                      {
                        "title" : "24",
                        "timingTiming" : {
                          "repeat" : {
                            "boundsRange" : {
                              "low" : {
                                "value" : 24,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              },
                              "high" : {
                                "value" : 24,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              }
                            },
                            "frequency" : 1
                          }
                        },
                        "action" : [
                          {
                            "title" : "XY",
                            "definitionCanonical" : "http://example-server.com/fhir/ActivityDefinition/cf2df6ab-5087-435c-35cb-a84572e756a2"
                          }
                        ]
                      }
                    ]
                  },
                  // ActivityDefinition/activityLongTerm25XY-24
                  //  3 months
                  //  todo put comments back in?
                  //  6 months
                  //  9 months
                  //  12 months
                  //  18 months
                  //  24 months
                  {
                    "title" : "Accelerated",
                    "description" : "40°C/75% RH",
                    "action" : [
                      {
                        "title" : "Initial",
                        "timingTiming" : {
                          "repeat" : {
                            "boundsRange" : {
                              "low" : {
                                "value" : 0,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              },
                              "high" : {
                                "value" : 0,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              }
                            },
                            "frequency" : 1
                          }
                        },
                        "action" : [
                          {
                            "title" : "XYZ",
                            "definitionCanonical" : "http://example-server.com/fhir/ActivityDefinition/6b96124b-1a44-0b6b-6783-d6c49360230b"
                          }
                        ]
                      },
                      // ActivityDefinition/activityAccelerated40XYZ-Initial
                      {
                        "title" : "3",
                        "timingTiming" : {
                          "repeat" : {
                            "boundsRange" : {
                              "low" : {
                                "value" : 3,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              },
                              "high" : {
                                "value" : 3,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              }
                            },
                            "frequency" : 1
                          }
                        },
                        "action" : [
                          {
                            "title" : "X",
                            "definitionCanonical" : "http://example-server.com/fhir/ActivityDefinition/096e3f32-798e-6792-76ad-4ea783521c50"
                          }
                        ]
                      },
                      // ActivityDefinition/activityAccelerated40X-3
                      {
                        "title" : "6",
                        "timingTiming" : {
                          "repeat" : {
                            "boundsRange" : {
                              "low" : {
                                "value" : 6,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              },
                              "high" : {
                                "value" : 6,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              }
                            },
                            "frequency" : 1
                          }
                        },
                        "action" : [
                          {
                            "title" : "X",
                            "definitionCanonical" : "http://example-server.com/fhir/ActivityDefinition/77f86b13-8193-3df7-8362-ab5e79ba541d"
                          }
                        ]
                      },
                      // ActivityDefinition/activityAccelerated40X-6
                      {
                        "title" : "9",
                        "timingTiming" : {
                          "repeat" : {
                            "boundsRange" : {
                              "low" : {
                                "value" : 9,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              },
                              "high" : {
                                "value" : 9,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              }
                            },
                            "frequency" : 1
                          }
                        },
                        "action" : [
                          {
                            "title" : "-"
                          }
                        ]
                      },
                      {
                        "title" : "12",
                        "timingTiming" : {
                          "repeat" : {
                            "boundsRange" : {
                              "low" : {
                                "value" : 12,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              },
                              "high" : {
                                "value" : 12,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              }
                            },
                            "frequency" : 1
                          }
                        },
                        "action" : [
                          {
                            "title" : "-"
                          }
                        ]
                      },
                      {
                        "title" : "18",
                        "timingTiming" : {
                          "repeat" : {
                            "boundsRange" : {
                              "low" : {
                                "value" : 18,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              },
                              "high" : {
                                "value" : 18,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              }
                            },
                            "frequency" : 1
                          }
                        },
                        "action" : [
                          {
                            "title" : "-"
                          }
                        ]
                      },
                      {
                        "title" : "24",
                        "timingTiming" : {
                          "repeat" : {
                            "boundsRange" : {
                              "low" : {
                                "value" : 24,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              },
                              "high" : {
                                "value" : 24,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              }
                            },
                            "frequency" : 1
                          }
                        },
                        "action" : [
                          {
                            "title" : "-"
                          }
                        ]
                      }
                    ]
                  }
                ]
              }
            ]
          }
        },
        //  end of long term
        //  0 months is first one - but results for this are not needed, because and zero months is the same for both long term and accelerated
        {
          "fullUrl" : "urn:uuid:3a0cde98-4a73-6d67-1dfc-08e3fc9646a2",
          "resource" : {
            "resourceType" : "SpecimenDefinition",
            "id" : "3a0cde98-4a73-6d67-1dfc-08e3fc9646a2",
            "meta" : // <id value="specimenDefStoredAt25"/>
            // specimendefinition-drug-pq-ex1
            {
              "profile" : [
                🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/SpecimenDefinition-drug-pq"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"SpecimenDefinition_3a0cde98-4a73-6d67-1dfc-08e3fc9646a2\"> </a><p><b>Generated Narrative: SpecimenDefinition</b><a name=\"3a0cde98-4a73-6d67-1dfc-08e3fc9646a2\"> </a><a name=\"hc3a0cde98-4a73-6d67-1dfc-08e3fc9646a2\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource SpecimenDefinition &quot;3a0cde98-4a73-6d67-1dfc-08e3fc9646a2&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-SpecimenDefinition-drug-pq.html\">SpecimenDefinition - Drug PQ</a></p></div><p><b>url</b>: <code>http://example-server.com/fhir/SpecimenDefinition/3a0cde98-4a73-6d67-1dfc-08e3fc9646a2</code></p><p><b>status</b>: active</p><blockquote><p><b>typeTested</b></p><p><b>preference</b>: preferred</p><h3>Handlings</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Instruction</b></td></tr><tr><td style=\"display: none\">*</td><td>25°C/60% RH</td></tr></table></blockquote></div>"
            },
            "url" : "http://example-server.com/fhir/SpecimenDefinition/3a0cde98-4a73-6d67-1dfc-08e3fc9646a2",
            "status" : "active",
            "typeTested" : [
              // http://example-server.com/fhir/SpecimenDefinition/3a0cde98-4a73-6d67-1dfc-08e3fc9646a2
              {
                "preference" : "preferred",
                "handling" : [
                  {
                    "instruction" : "25°C/60% RH"
                  }
                ]
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:610ca25c-6126-6117-8d4d-9458ccc33ce2",
          "resource" : {
            "resourceType" : "ActivityDefinition",
            "id" : "610ca25c-6126-6117-8d4d-9458ccc33ce2",
            "meta" : //  <id value="activityLongTerm25X-3"/>
            // activitydefinition-stability-test-dxpq-ex1
            {
              "profile" : [
                🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/ActivityDefinition-test-drug-pq"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ActivityDefinition_610ca25c-6126-6117-8d4d-9458ccc33ce2\"> </a><p><b>Generated Narrative: ActivityDefinition</b><a name=\"610ca25c-6126-6117-8d4d-9458ccc33ce2\"> </a><a name=\"hc610ca25c-6126-6117-8d4d-9458ccc33ce2\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ActivityDefinition &quot;610ca25c-6126-6117-8d4d-9458ccc33ce2&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ActivityDefinition-test-drug-pq.html\">ActivityDefinition - Test Drug PQ</a></p></div><p><b>url</b>: <code>http://example-server.com/fhir/ActivityDefinition/610ca25c-6126-6117-8d4d-9458ccc33ce2</code></p><p><b>title</b>: Long-term - 25°C/60% RH - X</p><p><b>status</b>: active</p><p><b>observationRequirement</b>: <a href=\"http://example-server.com/fhir/ObservationDefinition/d1d252cf-9d58-43a0-85f6-56a7f7f92774\">http://example-server.com/fhir/ObservationDefinition/d1d252cf-9d58-43a0-85f6-56a7f7f92774</a></p></div>"
            },
            "url" : "http://example-server.com/fhir/ActivityDefinition/610ca25c-6126-6117-8d4d-9458ccc33ce2",
            "title" : "Long-term - 25°C/60% RH - X",
            "status" : "active",
            "observationRequirement" : [
              "http://example-server.com/fhir/ObservationDefinition/d1d252cf-9d58-43a0-85f6-56a7f7f92774"
            ]
          }
        },
        // http://example-server.com/fhir/ActivityDefinition/610ca25c-6126-6117-8d4d-9458ccc33ce2
        //  changed here to not have url in front
        // ObservationDefinition/longTerm25X
        {
          "fullUrl" : "urn:uuid:d99c1b63-2d32-4887-8157-525cc8ae4732",
          "resource" : {
            "resourceType" : "ActivityDefinition",
            "id" : "d99c1b63-2d32-4887-8157-525cc8ae4732",
            "meta" : // activityLongTerm25X-6
            {
              "profile" : [
                🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/ActivityDefinition-test-drug-pq"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ActivityDefinition_d99c1b63-2d32-4887-8157-525cc8ae4732\"> </a><p><b>Generated Narrative: ActivityDefinition</b><a name=\"d99c1b63-2d32-4887-8157-525cc8ae4732\"> </a><a name=\"hcd99c1b63-2d32-4887-8157-525cc8ae4732\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ActivityDefinition &quot;d99c1b63-2d32-4887-8157-525cc8ae4732&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ActivityDefinition-test-drug-pq.html\">ActivityDefinition - Test Drug PQ</a></p></div><p><b>url</b>: <code>http://example-server.com/fhir/ActivityDefinition/d99c1b63-2d32-4887-8157-525cc8ae4732</code></p><p><b>title</b>: Long-term - 25°C/60% RH - X</p><p><b>status</b>: active</p><p><b>observationRequirement</b>: <a href=\"http://example-server.com/fhir/ObservationDefinition/d1d252cf-9d58-43a0-85f6-56a7f7f92774\">http://example-server.com/fhir/ObservationDefinition/d1d252cf-9d58-43a0-85f6-56a7f7f92774</a></p></div>"
            },
            "url" : "http://example-server.com/fhir/ActivityDefinition/d99c1b63-2d32-4887-8157-525cc8ae4732",
            "title" : "Long-term - 25°C/60% RH - X",
            "status" : "active",
            "observationRequirement" : [
              "http://example-server.com/fhir/ObservationDefinition/d1d252cf-9d58-43a0-85f6-56a7f7f92774"
            ]
          }
        },
        // http://example-server.com/fhir/ActivityDefinition/d99c1b63-2d32-4887-8157-525cc8ae4732
        // ObservationDefinition/longTerm25X
        {
          "fullUrl" : "urn:uuid:38704856-0acf-95f0-000f-a933b6862fa0",
          "resource" : {
            "resourceType" : "ActivityDefinition",
            "id" : "38704856-0acf-95f0-000f-a933b6862fa0",
            "meta" : // activityLongTerm25X-9
            {
              "profile" : [
                🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/ActivityDefinition-test-drug-pq"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ActivityDefinition_38704856-0acf-95f0-000f-a933b6862fa0\"> </a><p><b>Generated Narrative: ActivityDefinition</b><a name=\"38704856-0acf-95f0-000f-a933b6862fa0\"> </a><a name=\"hc38704856-0acf-95f0-000f-a933b6862fa0\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ActivityDefinition &quot;38704856-0acf-95f0-000f-a933b6862fa0&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ActivityDefinition-test-drug-pq.html\">ActivityDefinition - Test Drug PQ</a></p></div><p><b>url</b>: <code>http://example-server.com/fhir/ActivityDefinition/38704856-0acf-95f0-000f-a933b6862fa0</code></p><p><b>title</b>: Long-term - 25°C/60% RH - X</p><p><b>status</b>: active</p><p><b>observationRequirement</b>: <a href=\"http://example-server.com/fhir/ObservationDefinition/d1d252cf-9d58-43a0-85f6-56a7f7f92774\">http://example-server.com/fhir/ObservationDefinition/d1d252cf-9d58-43a0-85f6-56a7f7f92774</a></p></div>"
            },
            "url" : "http://example-server.com/fhir/ActivityDefinition/38704856-0acf-95f0-000f-a933b6862fa0",
            "title" : "Long-term - 25°C/60% RH - X",
            "status" : "active",
            "observationRequirement" : [
              "http://example-server.com/fhir/ObservationDefinition/d1d252cf-9d58-43a0-85f6-56a7f7f92774"
            ]
          }
        },
        // http://example-server.com/fhir/ActivityDefinition/38704856-0acf-95f0-000f-a933b6862fa0
        // ObservationDefinition/longTerm25X
        {
          "fullUrl" : "urn:uuid:4bfe1ee8-91ed-5c1b-3045-c749bb9d1d90",
          "resource" : {
            "resourceType" : "ActivityDefinition",
            "id" : "4bfe1ee8-91ed-5c1b-3045-c749bb9d1d90",
            "meta" : // id value="activityLongTerm25XYZ-Initial"/
            // activitydefinition-test-drug-pq-ex1
            {
              "profile" : [
                🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/ActivityDefinition-test-drug-pq"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ActivityDefinition_4bfe1ee8-91ed-5c1b-3045-c749bb9d1d90\"> </a><p><b>Generated Narrative: ActivityDefinition</b><a name=\"4bfe1ee8-91ed-5c1b-3045-c749bb9d1d90\"> </a><a name=\"hc4bfe1ee8-91ed-5c1b-3045-c749bb9d1d90\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ActivityDefinition &quot;4bfe1ee8-91ed-5c1b-3045-c749bb9d1d90&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ActivityDefinition-test-drug-pq.html\">ActivityDefinition - Test Drug PQ</a></p></div><p><b>url</b>: <code>http://example-server.com/fhir/ActivityDefinition/4bfe1ee8-91ed-5c1b-3045-c749bb9d1d90</code></p><p><b>title</b>: Long-term - 25°C/60% RH - XYZ</p><p><b>status</b>: active</p><p><b>observationRequirement</b>: <a href=\"http://example-server.com/fhir/ObservationDefinition/d1d252cf-9d58-43a0-85f6-56a7f7f92774\">http://example-server.com/fhir/ObservationDefinition/d1d252cf-9d58-43a0-85f6-56a7f7f92774</a>, <a href=\"http://example-server.com/fhir/ObservationDefinition/b62b9524-53af-84ae-1071-2867a2169851\">http://example-server.com/fhir/ObservationDefinition/b62b9524-53af-84ae-1071-2867a2169851</a>, <a href=\"http://example-server.com/fhir/ObservationDefinition/363384c8-0d79-5ff0-5538-4933f99d6409\">http://example-server.com/fhir/ObservationDefinition/363384c8-0d79-5ff0-5538-4933f99d6409</a></p></div>"
            },
            "url" : "http://example-server.com/fhir/ActivityDefinition/4bfe1ee8-91ed-5c1b-3045-c749bb9d1d90",
            "title" : "Long-term - 25°C/60% RH - XYZ",
            "status" : "active",
            "observationRequirement" : [
              "http://example-server.com/fhir/ObservationDefinition/d1d252cf-9d58-43a0-85f6-56a7f7f92774",
              "http://example-server.com/fhir/ObservationDefinition/b62b9524-53af-84ae-1071-2867a2169851",
              "http://example-server.com/fhir/ObservationDefinition/363384c8-0d79-5ff0-5538-4933f99d6409"
            ]
          }
        },
        // http://example-server.com/fhir/ActivityDefinition/4bfe1ee8-91ed-5c1b-3045-c749bb9d1d90
        // ObservationDefinition/longTerm25X
        // ObservationDefinition/longTerm25Y
        // ObservationDefinition/longTerm25Z
        {
          "fullUrl" : "urn:uuid:f19a68b0-4ba1-7288-635e-12783035935b",
          "resource" : {
            "resourceType" : "ActivityDefinition",
            "id" : "f19a68b0-4ba1-7288-635e-12783035935b",
            "meta" : // activityLongTerm25XY-12
            {
              "profile" : [
                🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/ActivityDefinition-test-drug-pq"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ActivityDefinition_f19a68b0-4ba1-7288-635e-12783035935b\"> </a><p><b>Generated Narrative: ActivityDefinition</b><a name=\"f19a68b0-4ba1-7288-635e-12783035935b\"> </a><a name=\"hcf19a68b0-4ba1-7288-635e-12783035935b\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ActivityDefinition &quot;f19a68b0-4ba1-7288-635e-12783035935b&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ActivityDefinition-test-drug-pq.html\">ActivityDefinition - Test Drug PQ</a></p></div><p><b>url</b>: <code>http://example-server.com/fhir/ActivityDefinition/f19a68b0-4ba1-7288-635e-12783035935b</code></p><p><b>title</b>: Long-term - 25°C/60% RH - XY</p><p><b>status</b>: active</p><p><b>observationRequirement</b>: <a href=\"http://example-server.com/fhir/ObservationDefinition/d1d252cf-9d58-43a0-85f6-56a7f7f92774\">http://example-server.com/fhir/ObservationDefinition/d1d252cf-9d58-43a0-85f6-56a7f7f92774</a>, <a href=\"http://example-server.com/fhir/ObservationDefinition/b62b9524-53af-84ae-1071-2867a2169851\">http://example-server.com/fhir/ObservationDefinition/b62b9524-53af-84ae-1071-2867a2169851</a></p></div>"
            },
            "url" : "http://example-server.com/fhir/ActivityDefinition/f19a68b0-4ba1-7288-635e-12783035935b",
            "title" : "Long-term - 25°C/60% RH - XY",
            "status" : "active",
            "observationRequirement" : [
              "http://example-server.com/fhir/ObservationDefinition/d1d252cf-9d58-43a0-85f6-56a7f7f92774",
              "http://example-server.com/fhir/ObservationDefinition/b62b9524-53af-84ae-1071-2867a2169851"
            ]
          }
        },
        // http://example-server.com/fhir/ActivityDefinition/f19a68b0-4ba1-7288-635e-12783035935b
        // ObservationDefinition/longTerm25X
        // ObservationDefinition/longTerm25Y
        {
          "fullUrl" : "urn:uuid:ce2df6ab-5087-435c-35cb-a84572e756a2",
          "resource" : {
            "resourceType" : "ActivityDefinition",
            "id" : "ce2df6ab-5087-435c-35cb-a84572e756a2",
            "meta" : // activityLongTerm25XY-18
            {
              "profile" : [
                🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/ActivityDefinition-test-drug-pq"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ActivityDefinition_ce2df6ab-5087-435c-35cb-a84572e756a2\"> </a><p><b>Generated Narrative: ActivityDefinition</b><a name=\"ce2df6ab-5087-435c-35cb-a84572e756a2\"> </a><a name=\"hcce2df6ab-5087-435c-35cb-a84572e756a2\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ActivityDefinition &quot;ce2df6ab-5087-435c-35cb-a84572e756a2&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ActivityDefinition-test-drug-pq.html\">ActivityDefinition - Test Drug PQ</a></p></div><p><b>url</b>: <code>http://example-server.com/fhir/ActivityDefinition/ce2df6ab-5087-435c-35cb-a84572e756a2</code></p><p><b>title</b>: Long-term - 25°C/60% RH - XY</p><p><b>status</b>: active</p><p><b>observationRequirement</b>: <a href=\"http://example-server.com/fhir/ObservationDefinition/d1d252cf-9d58-43a0-85f6-56a7f7f92774\">http://example-server.com/fhir/ObservationDefinition/d1d252cf-9d58-43a0-85f6-56a7f7f92774</a>, <a href=\"http://example-server.com/fhir/ObservationDefinition/b62b9524-53af-84ae-1071-2867a2169851\">http://example-server.com/fhir/ObservationDefinition/b62b9524-53af-84ae-1071-2867a2169851</a></p></div>"
            },
            "url" : "http://example-server.com/fhir/ActivityDefinition/ce2df6ab-5087-435c-35cb-a84572e756a2",
            "title" : "Long-term - 25°C/60% RH - XY",
            "status" : "active",
            "observationRequirement" : [
              "http://example-server.com/fhir/ObservationDefinition/d1d252cf-9d58-43a0-85f6-56a7f7f92774",
              "http://example-server.com/fhir/ObservationDefinition/b62b9524-53af-84ae-1071-2867a2169851"
            ]
          }
        },
        // http://example-server.com/fhir/ActivityDefinition/ce2df6ab-5087-435c-35cb-a84572e756a2
        // ObservationDefinition/longTerm25X
        // ObservationDefinition/longTerm25Y
        {
          "fullUrl" : "urn:uuid:cf2df6ab-5087-435c-35cb-a84572e756a2",
          "resource" : {
            "resourceType" : "ActivityDefinition",
            "id" : "cf2df6ab-5087-435c-35cb-a84572e756a2",
            "meta" : // activityLongTerm25XY-24
            {
              "profile" : [
                🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/ActivityDefinition-test-drug-pq"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ActivityDefinition_cf2df6ab-5087-435c-35cb-a84572e756a2\"> </a><p><b>Generated Narrative: ActivityDefinition</b><a name=\"cf2df6ab-5087-435c-35cb-a84572e756a2\"> </a><a name=\"hccf2df6ab-5087-435c-35cb-a84572e756a2\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ActivityDefinition &quot;cf2df6ab-5087-435c-35cb-a84572e756a2&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ActivityDefinition-test-drug-pq.html\">ActivityDefinition - Test Drug PQ</a></p></div><p><b>url</b>: <code>http://example-server.com/fhir/ActivityDefinition/cf2df6ab-5087-435c-35cb-a84572e756a2</code></p><p><b>title</b>: Long-term - 25°C/60% RH - XY</p><p><b>status</b>: active</p><p><b>observationRequirement</b>: <a href=\"http://example-server.com/fhir/ObservationDefinition/d1d252cf-9d58-43a0-85f6-56a7f7f92774\">http://example-server.com/fhir/ObservationDefinition/d1d252cf-9d58-43a0-85f6-56a7f7f92774</a>, <a href=\"http://example-server.com/fhir/ObservationDefinition/b62b9524-53af-84ae-1071-2867a2169851\">http://example-server.com/fhir/ObservationDefinition/b62b9524-53af-84ae-1071-2867a2169851</a></p></div>"
            },
            "url" : "http://example-server.com/fhir/ActivityDefinition/cf2df6ab-5087-435c-35cb-a84572e756a2",
            "title" : "Long-term - 25°C/60% RH - XY",
            "status" : "active",
            "observationRequirement" : [
              "http://example-server.com/fhir/ObservationDefinition/d1d252cf-9d58-43a0-85f6-56a7f7f92774",
              "http://example-server.com/fhir/ObservationDefinition/b62b9524-53af-84ae-1071-2867a2169851"
            ]
          }
        },
        // http://example-server.com/fhir/ActivityDefinition/cf2df6ab-5087-435c-35cb-a84572e756a2
        // ObservationDefinition/longTerm25X
        // ObservationDefinition/longTerm25Y
        {
          "fullUrl" : "urn:uuid:d1d252cf-9d58-43a0-85f6-56a7f7f92774",
          "resource" : //  can have others
          {
            "resourceType" : "ObservationDefinition",
            "id" : "d1d252cf-9d58-43a0-85f6-56a7f7f92774",
            "meta" : // longTerm25X
            // id value="observationdefinition-test-method-drug-pq-ex1"/
            {
              "profile" : [
                🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/ObservationDefinition-test-method-drug-pq"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_d1d252cf-9d58-43a0-85f6-56a7f7f92774\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"d1d252cf-9d58-43a0-85f6-56a7f7f92774\"> </a><a name=\"hcd1d252cf-9d58-43a0-85f6-56a7f7f92774\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;d1d252cf-9d58-43a0-85f6-56a7f7f92774&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ObservationDefinition-test-method-drug-pq.html\">ObservationDefinition - Test Method PQ</a></p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/d1d252cf-9d58-43a0-85f6-56a7f7f92774</code></p><p><b>title</b>: X</p><p><b>status</b>: active</p><p><b>code</b>: Battery of tests 'X' at 25°C/60% RH <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>specimen</b>: See on this page: SpecimenDefinition/3a0cde98-4a73-6d67-1dfc-08e3fc9646a2</p><p><b>hasMember</b>: </p><ul><li>See on this page: ObservationDefinition/1178fc31-0cfd-8c60-0b5b-9ae2850c6774</li><li>See on this page: ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f</li><li>See on this page: ObservationDefinition/186eb33e-a01d-4252-166c-b5ba5e8a697c</li></ul></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/d1d252cf-9d58-43a0-85f6-56a7f7f92774",
            "title" : "X",
            "status" : "active",
            "code" : // http://hl7.org/fhir/uv/pharm-quality/ObservationDefinition/observationdefinition-test-method-drug-pq-ex1
            {
              "text" : "Battery of tests 'X' at 25°C/60% RH"
            },
            "specimen" : [
              {
                "reference" : "SpecimenDefinition/3a0cde98-4a73-6d67-1dfc-08e3fc9646a2"
              }
            ],
            "hasMember" : [
              // SpecimenDefinition/specimendefinition-drug-pq-ex1
              {
                "reference" : "ObservationDefinition/1178fc31-0cfd-8c60-0b5b-9ae2850c6774"
              },
              // ObservationDefinition/Description
              {
                "reference" : "ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f"
              },
              // ObservationDefinition/Degradation
              {
                "reference" : "ObservationDefinition/186eb33e-a01d-4252-166c-b5ba5e8a697c"
              }
            ]
          }
        },
        // ObservationDefinition/Water
        {
          "fullUrl" : "urn:uuid:1178fc31-0cfd-8c60-0b5b-9ae2850c6774",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "1178fc31-0cfd-8c60-0b5b-9ae2850c6774",
            "meta" : // Description
            {
              "profile" : [
                🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/ObservationDefinition-test-method-drug-pq"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_1178fc31-0cfd-8c60-0b5b-9ae2850c6774\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"1178fc31-0cfd-8c60-0b5b-9ae2850c6774\"> </a><a name=\"hc1178fc31-0cfd-8c60-0b5b-9ae2850c6774\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;1178fc31-0cfd-8c60-0b5b-9ae2850c6774&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ObservationDefinition-test-method-drug-pq.html\">ObservationDefinition - Test Method PQ</a></p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/1178fc31-0cfd-8c60-0b5b-9ae2850c6774</code></p><p><b>title</b>: Description</p><p><b>status</b>: active</p><p><b>code</b>: Description <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DESC)</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td></tr><tr><td style=\"display: none\">*</td><td/></tr></table></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/1178fc31-0cfd-8c60-0b5b-9ae2850c6774",
            "title" : "Description",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/1178fc31-0cfd-8c60-0b5b-9ae2850c6774
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "DESC",
                  "display" : "Description"
                }
              ],
              "text" : "Description"
            },
            "qualifiedValue" : [
              {
                "extension" : [
                  {
                    "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-text-pq",
                    "valueString" : "An orange film-coated tablet, debossed with 175 on one side"
                  }
                ]
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:2c5683d6-6e94-825b-056a-129a04c95e2f",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "2c5683d6-6e94-825b-056a-129a04c95e2f",
            "meta" : // Degradation
            {
              "profile" : [
                🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/ObservationDefinition-test-method-drug-pq"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_2c5683d6-6e94-825b-056a-129a04c95e2f\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"2c5683d6-6e94-825b-056a-129a04c95e2f\"> </a><a name=\"hc2c5683d6-6e94-825b-056a-129a04c95e2f\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;2c5683d6-6e94-825b-056a-129a04c95e2f&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ObservationDefinition-test-method-drug-pq.html\">ObservationDefinition - Test Method PQ</a></p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f</code></p><p><b>title</b>: Degradation Products by HPLC (% w/w)</p><p><b>status</b>: active</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: Impurity 1 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>range</b>: ?-0.8</p></blockquote><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: Impurity 2 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>range</b>: ?-0.4</p></blockquote><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: Impurity 3 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>range</b>: ?-0.4</p></blockquote><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: Any Unspecified Degradation Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>range</b>: ?-0.2</p></blockquote><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: Total Degradation Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>range</b>: ?-2.3</p></blockquote><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td></tr></table></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f",
            "title" : "Degradation Products by HPLC (% w/w)",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "DGP",
                  "display" : "Degradation Products"
                }
              ]
            },
            "qualifiedValue" : [
              {
                "appliesTo" : [
                  {
                    "text" : "Impurity 1"
                  }
                ],
                "range" : //  could be a code
                {
                  "high" : {
                    "value" : 0.8,
                    "unit" : "% w/w",
                    "system" : "http://unitsofmeasure.org",
                    "code" : "%"
                  }
                }
              },
              {
                "appliesTo" : [
                  {
                    "text" : "Impurity 2"
                  }
                ],
                "range" : {
                  "high" : {
                    "value" : 0.4,
                    "unit" : "% w/w",
                    "system" : "http://unitsofmeasure.org",
                    "code" : "%"
                  }
                }
              },
              {
                "appliesTo" : [
                  {
                    "text" : "Impurity 3"
                  }
                ],
                "range" : {
                  "high" : {
                    "value" : 0.4,
                    "unit" : "% w/w",
                    "system" : "http://unitsofmeasure.org",
                    "code" : "%"
                  }
                }
              },
              {
                "appliesTo" : [
                  {
                    "text" : "Any Unspecified Degradation Impurity"
                  }
                ],
                "range" : {
                  "high" : {
                    "value" : 0.2,
                    "unit" : "% w/w",
                    "system" : "http://unitsofmeasure.org",
                    "code" : "%"
                  }
                }
              },
              {
                "appliesTo" : [
                  {
                    "text" : "Total Degradation Impurities"
                  }
                ],
                "range" : {
                  "high" : {
                    "value" : 2.3,
                    "unit" : "% w/w",
                    "system" : "http://unitsofmeasure.org",
                    "code" : "%"
                  }
                }
              }
            ],
            "component" : [
              {
                "code" : //  are expected to have a component that says what impurity this one is
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "IMP",
                      "display" : "Impurity"
                    }
                  ]
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:186eb33e-a01d-4252-166c-b5ba5e8a697c",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "186eb33e-a01d-4252-166c-b5ba5e8a697c",
            "meta" : // Water
            // id value="observationdefinition-test-method-drug-pq-ex2"/
            {
              "profile" : [
                🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/ObservationDefinition-test-method-drug-pq"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_186eb33e-a01d-4252-166c-b5ba5e8a697c\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"186eb33e-a01d-4252-166c-b5ba5e8a697c\"> </a><a name=\"hc186eb33e-a01d-4252-166c-b5ba5e8a697c\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;186eb33e-a01d-4252-166c-b5ba5e8a697c&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ObservationDefinition-test-method-drug-pq.html\">ObservationDefinition - Test Method PQ</a></p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/186eb33e-a01d-4252-166c-b5ba5e8a697c</code></p><p><b>title</b>: Water Content (% w/w) (Mean)</p><p><b>status</b>: active</p><p><b>code</b>: Water Content <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#WaterContent)</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>?-0.2</td></tr></table></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/186eb33e-a01d-4252-166c-b5ba5e8a697c",
            "title" : "Water Content (% w/w) (Mean)",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/186eb33e-a01d-4252-166c-b5ba5e8a697c
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "WaterContent",
                  "display" : "Water Content"
                }
              ],
              "text" : "Water Content"
            },
            "qualifiedValue" : [
              {
                "range" : {
                  "high" : {
                    "value" : 0.2,
                    "unit" : "% w/w",
                    "system" : "http://unitsofmeasure.org",
                    "code" : "%"
                  }
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:b62b9524-53af-84ae-1071-2867a2169851",
          "resource" : //  can have others
          {
            "resourceType" : "ObservationDefinition",
            "id" : "b62b9524-53af-84ae-1071-2867a2169851",
            "meta" : // longTerm25Y
            {
              "profile" : [
                🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/ObservationDefinition-test-method-drug-pq"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_b62b9524-53af-84ae-1071-2867a2169851\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"b62b9524-53af-84ae-1071-2867a2169851\"> </a><a name=\"hcb62b9524-53af-84ae-1071-2867a2169851\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;b62b9524-53af-84ae-1071-2867a2169851&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ObservationDefinition-test-method-drug-pq.html\">ObservationDefinition - Test Method PQ</a></p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/b62b9524-53af-84ae-1071-2867a2169851</code></p><p><b>title</b>: Y</p><p><b>status</b>: active</p><p><b>code</b>: Battery of tests 'Y' at 25°C/60% RH <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>specimen</b>: See on this page: SpecimenDefinition/3a0cde98-4a73-6d67-1dfc-08e3fc9646a2</p><p><b>hasMember</b>: See on this page: ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</p></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/b62b9524-53af-84ae-1071-2867a2169851",
            "title" : "Y",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/b62b9524-53af-84ae-1071-2867a2169851
            {
              "text" : "Battery of tests 'Y' at 25°C/60% RH"
            },
            "specimen" : [
              {
                "reference" : "SpecimenDefinition/3a0cde98-4a73-6d67-1dfc-08e3fc9646a2"
              }
            ],
            "hasMember" : [
              // SpecimenDefinition/specimendefinition-drug-pq-ex1
              {
                "reference" : "ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e"
              }
            ]
          }
        },
        // ObservationDefinition/Microbiological
        {
          "fullUrl" : "urn:uuid:73d9d304-a0b8-31b6-1165-346563b9305e",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "73d9d304-a0b8-31b6-1165-346563b9305e",
            "meta" : // Microbiological
            {
              "profile" : [
                🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/ObservationDefinition-test-method-drug-pq"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_73d9d304-a0b8-31b6-1165-346563b9305e\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"73d9d304-a0b8-31b6-1165-346563b9305e\"> </a><a name=\"hc73d9d304-a0b8-31b6-1165-346563b9305e\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;73d9d304-a0b8-31b6-1165-346563b9305e&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ObservationDefinition-test-method-drug-pq.html\">ObservationDefinition - Test Method PQ</a></p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</code></p><p><b>title</b>: Microbiological</p><p><b>status</b>: active</p><p><b>code</b>: Microbiological Quality <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Microbiological Quality)</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td></tr><tr><td style=\"display: none\">*</td><td/></tr></table></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e",
            "title" : "Microbiological",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Microbiological Quality",
                  "display" : "Microbiological Quality"
                }
              ],
              "text" : "Microbiological Quality"
            },
            "qualifiedValue" : [
              {
                "extension" : [
                  {
                    "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-text-pq",
                    "valueString" : "Complies with PhEur"
                  }
                ]
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:363384c8-0d79-5ff0-5538-4933f99d6409",
          "resource" : //  can have others
          {
            "resourceType" : "ObservationDefinition",
            "id" : "363384c8-0d79-5ff0-5538-4933f99d6409",
            "meta" : // longTerm25Z
            {
              "profile" : [
                🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/ObservationDefinition-test-method-drug-pq"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_363384c8-0d79-5ff0-5538-4933f99d6409\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"363384c8-0d79-5ff0-5538-4933f99d6409\"> </a><a name=\"hc363384c8-0d79-5ff0-5538-4933f99d6409\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;363384c8-0d79-5ff0-5538-4933f99d6409&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ObservationDefinition-test-method-drug-pq.html\">ObservationDefinition - Test Method PQ</a></p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/363384c8-0d79-5ff0-5538-4933f99d6409</code></p><p><b>title</b>: Z</p><p><b>status</b>: active</p><p><b>code</b>: Battery of tests 'Z' at 25°C/60% RH <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>specimen</b>: See on this page: SpecimenDefinition/3a0cde98-4a73-6d67-1dfc-08e3fc9646a2</p><p><b>hasMember</b>: See on this page: ObservationDefinition/ef781c18-8e86-7859-209b-469ee9ad42d8</p></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/363384c8-0d79-5ff0-5538-4933f99d6409",
            "title" : "Z",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/363384c8-0d79-5ff0-5538-4933f99d6409
            {
              "text" : "Battery of tests 'Z' at 25°C/60% RH"
            },
            "specimen" : [
              {
                "reference" : "SpecimenDefinition/3a0cde98-4a73-6d67-1dfc-08e3fc9646a2"
              }
            ],
            "hasMember" : [
              // SpecimenDefinition/specimendefinition-drug-pq-ex1
              {
                "reference" : "ObservationDefinition/ef781c18-8e86-7859-209b-469ee9ad42d8"
              }
            ]
          }
        },
        // ObservationDefinition/Uniformity
        {
          "fullUrl" : "urn:uuid:ef781c18-8e86-7859-209b-469ee9ad42d8",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "ef781c18-8e86-7859-209b-469ee9ad42d8",
            "meta" : // Uniformity
            {
              "profile" : [
                🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/ObservationDefinition-test-method-drug-pq"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_ef781c18-8e86-7859-209b-469ee9ad42d8\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"ef781c18-8e86-7859-209b-469ee9ad42d8\"> </a><a name=\"hcef781c18-8e86-7859-209b-469ee9ad42d8\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;ef781c18-8e86-7859-209b-469ee9ad42d8&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ObservationDefinition-test-method-drug-pq.html\">ObservationDefinition - Test Method PQ</a></p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/ef781c18-8e86-7859-209b-469ee9ad42d8</code></p><p><b>title</b>: Uniformity of dosage</p><p><b>status</b>: active</p><p><b>code</b>: uniformity of dosage units (by weight) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#uniformity-dosage)</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td></tr><tr><td style=\"display: none\">*</td><td/></tr></table></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/ef781c18-8e86-7859-209b-469ee9ad42d8",
            "title" : "Uniformity of dosage",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/ef781c18-8e86-7859-209b-469ee9ad42d8
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "uniformity-dosage",
                  "display" : "uniformity of dosage units (by weight)"
                }
              ],
              "text" : "uniformity of dosage units (by weight)"
            },
            "qualifiedValue" : [
              {
                "extension" : [
                  {
                    "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-text-pq",
                    "valueString" : "Complies"
                  }
                ]
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:e95109ac-5ef9-1723-3506-2ef2f2e33d87",
          "resource" : {
            "resourceType" : "SpecimenDefinition",
            "id" : "e95109ac-5ef9-1723-3506-2ef2f2e33d87",
            "text" : // specimenDefStoredAt40
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"SpecimenDefinition_e95109ac-5ef9-1723-3506-2ef2f2e33d87\"> </a><p><b>Generated Narrative: SpecimenDefinition</b><a name=\"e95109ac-5ef9-1723-3506-2ef2f2e33d87\"> </a><a name=\"hce95109ac-5ef9-1723-3506-2ef2f2e33d87\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource SpecimenDefinition &quot;e95109ac-5ef9-1723-3506-2ef2f2e33d87&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/SpecimenDefinition/e95109ac-5ef9-1723-3506-2ef2f2e33d87</code></p><p><b>status</b>: active</p><blockquote><p><b>typeTested</b></p><p><b>preference</b>: preferred</p><h3>Handlings</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Instruction</b></td></tr><tr><td style=\"display: none\">*</td><td>40°C/75% RH</td></tr></table></blockquote></div>"
            },
            "url" : "http://example-server.com/fhir/SpecimenDefinition/e95109ac-5ef9-1723-3506-2ef2f2e33d87",
            "status" : "active",
            "typeTested" : [
              // http://example-server.com/fhir/SpecimenDefinition/e95109ac-5ef9-1723-3506-2ef2f2e33d87
              {
                "preference" : "preferred",
                "handling" : [
                  {
                    "instruction" : "40°C/75% RH"
                  }
                ]
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:096e3f32-798e-6792-76ad-4ea783521c50",
          "resource" : {
            "resourceType" : "ActivityDefinition",
            "id" : "096e3f32-798e-6792-76ad-4ea783521c50",
            "meta" : // activityAccelerated40X-3
            {
              "profile" : [
                🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/ActivityDefinition-test-drug-pq"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ActivityDefinition_096e3f32-798e-6792-76ad-4ea783521c50\"> </a><p><b>Generated Narrative: ActivityDefinition</b><a name=\"096e3f32-798e-6792-76ad-4ea783521c50\"> </a><a name=\"hc096e3f32-798e-6792-76ad-4ea783521c50\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ActivityDefinition &quot;096e3f32-798e-6792-76ad-4ea783521c50&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ActivityDefinition-test-drug-pq.html\">ActivityDefinition - Test Drug PQ</a></p></div><p><b>url</b>: <code>http://example-server.com/fhir/ActivityDefinition/096e3f32-798e-6792-76ad-4ea783521c50</code></p><p><b>title</b>: Accelerated - 40°C/70% RH - X</p><p><b>status</b>: active</p><p><b>observationRequirement</b>: <a href=\"http://example-server.com/fhir/ObservationDefinition/792ae02e-5ba3-13d1-8cc2-fd24a22f7f0b\">http://example-server.com/fhir/ObservationDefinition/792ae02e-5ba3-13d1-8cc2-fd24a22f7f0b</a></p></div>"
            },
            "url" : "http://example-server.com/fhir/ActivityDefinition/096e3f32-798e-6792-76ad-4ea783521c50",
            "title" : "Accelerated - 40°C/70% RH - X",
            "status" : "active",
            "observationRequirement" : [
              "http://example-server.com/fhir/ObservationDefinition/792ae02e-5ba3-13d1-8cc2-fd24a22f7f0b"
            ]
          }
        },
        // http://example-server.com/fhir/ActivityDefinition/096e3f32-798e-6792-76ad-4ea783521c50
        // ObservationDefinition/accelerated40X
        {
          "fullUrl" : "urn:uuid:77f86b13-8193-3df7-8362-ab5e79ba541d",
          "resource" : {
            "resourceType" : "ActivityDefinition",
            "id" : "77f86b13-8193-3df7-8362-ab5e79ba541d",
            "meta" : // activityAccelerated40X-6
            {
              "profile" : [
                🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/ActivityDefinition-test-drug-pq"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ActivityDefinition_77f86b13-8193-3df7-8362-ab5e79ba541d\"> </a><p><b>Generated Narrative: ActivityDefinition</b><a name=\"77f86b13-8193-3df7-8362-ab5e79ba541d\"> </a><a name=\"hc77f86b13-8193-3df7-8362-ab5e79ba541d\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ActivityDefinition &quot;77f86b13-8193-3df7-8362-ab5e79ba541d&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ActivityDefinition-test-drug-pq.html\">ActivityDefinition - Test Drug PQ</a></p></div><p><b>url</b>: <code>http://example-server.com/fhir/ActivityDefinition/77f86b13-8193-3df7-8362-ab5e79ba541d</code></p><p><b>title</b>: Accelerated - 40°C/70% RH - X</p><p><b>status</b>: active</p><p><b>observationRequirement</b>: <a href=\"http://example-server.com/fhir/ObservationDefinition/792ae02e-5ba3-13d1-8cc2-fd24a22f7f0b\">http://example-server.com/fhir/ObservationDefinition/792ae02e-5ba3-13d1-8cc2-fd24a22f7f0b</a></p></div>"
            },
            "url" : "http://example-server.com/fhir/ActivityDefinition/77f86b13-8193-3df7-8362-ab5e79ba541d",
            "title" : "Accelerated - 40°C/70% RH - X",
            "status" : "active",
            "observationRequirement" : [
              "http://example-server.com/fhir/ObservationDefinition/792ae02e-5ba3-13d1-8cc2-fd24a22f7f0b"
            ]
          }
        },
        // http://example-server.com/fhir/ActivityDefinition/77f86b13-8193-3df7-8362-ab5e79ba541d
        // ObservationDefinition/accelerated40X
        {
          "fullUrl" : "urn:uuid:6b96124b-1a44-0b6b-6783-d6c49360230b",
          "resource" : {
            "resourceType" : "ActivityDefinition",
            "id" : "6b96124b-1a44-0b6b-6783-d6c49360230b",
            "meta" : // activityAccelerated40XYZ-Initial
            {
              "profile" : [
                🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/ActivityDefinition-test-drug-pq"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ActivityDefinition_6b96124b-1a44-0b6b-6783-d6c49360230b\"> </a><p><b>Generated Narrative: ActivityDefinition</b><a name=\"6b96124b-1a44-0b6b-6783-d6c49360230b\"> </a><a name=\"hc6b96124b-1a44-0b6b-6783-d6c49360230b\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ActivityDefinition &quot;6b96124b-1a44-0b6b-6783-d6c49360230b&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ActivityDefinition-test-drug-pq.html\">ActivityDefinition - Test Drug PQ</a></p></div><p><b>url</b>: <code>http://example-server.com/fhir/ActivityDefinition/6b96124b-1a44-0b6b-6783-d6c49360230b</code></p><p><b>title</b>: Accelerated - 40°C/70% RH - XYZ</p><p><b>status</b>: active</p><p><b>observationRequirement</b>: <a href=\"http://example-server.com/fhir/ObservationDefinition/792ae02e-5ba3-13d1-8cc2-fd24a22f7f0b\">http://example-server.com/fhir/ObservationDefinition/792ae02e-5ba3-13d1-8cc2-fd24a22f7f0b</a>, <a href=\"http://example-server.com/fhir/ObservationDefinition/58cb0710-0ee6-1b7a-2a64-61a01df95ac2\">http://example-server.com/fhir/ObservationDefinition/58cb0710-0ee6-1b7a-2a64-61a01df95ac2</a>, <a href=\"http://example-server.com/fhir/ObservationDefinition/9bc183ee-6017-789b-8a6f-6a5c339f9ae0\">http://example-server.com/fhir/ObservationDefinition/9bc183ee-6017-789b-8a6f-6a5c339f9ae0</a></p></div>"
            },
            "url" : "http://example-server.com/fhir/ActivityDefinition/6b96124b-1a44-0b6b-6783-d6c49360230b",
            "title" : "Accelerated - 40°C/70% RH - XYZ",
            "status" : "active",
            "observationRequirement" : [
              "http://example-server.com/fhir/ObservationDefinition/792ae02e-5ba3-13d1-8cc2-fd24a22f7f0b",
              "http://example-server.com/fhir/ObservationDefinition/58cb0710-0ee6-1b7a-2a64-61a01df95ac2",
              "http://example-server.com/fhir/ObservationDefinition/9bc183ee-6017-789b-8a6f-6a5c339f9ae0"
            ]
          }
        },
        // http://example-server.com/fhir/ActivityDefinition/6b96124b-1a44-0b6b-6783-d6c49360230b
        // ObservationDefinition/accelerated40X
        // ObservationDefinition/accelerated40Y
        // ObservationDefinition/accelerated40Z
        {
          "fullUrl" : "urn:uuid:792ae02e-5ba3-13d1-8cc2-fd24a22f7f0b",
          "resource" : //  can have others
          {
            "resourceType" : "ObservationDefinition",
            "id" : "792ae02e-5ba3-13d1-8cc2-fd24a22f7f0b",
            "meta" : // accelerated40X
            {
              "profile" : [
                🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/ObservationDefinition-test-method-drug-pq"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_792ae02e-5ba3-13d1-8cc2-fd24a22f7f0b\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"792ae02e-5ba3-13d1-8cc2-fd24a22f7f0b\"> </a><a name=\"hc792ae02e-5ba3-13d1-8cc2-fd24a22f7f0b\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;792ae02e-5ba3-13d1-8cc2-fd24a22f7f0b&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ObservationDefinition-test-method-drug-pq.html\">ObservationDefinition - Test Method PQ</a></p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/792ae02e-5ba3-13d1-8cc2-fd24a22f7f0b</code></p><p><b>title</b>: X</p><p><b>status</b>: active</p><p><b>code</b>: Battery of tests 'X' at 40°C/75% RH <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>specimen</b>: See on this page: SpecimenDefinition/e95109ac-5ef9-1723-3506-2ef2f2e33d87</p><p><b>hasMember</b>: </p><ul><li>See on this page: ObservationDefinition/1178fc31-0cfd-8c60-0b5b-9ae2850c6774</li><li>See on this page: ObservationDefinition/186eb33e-a01d-4252-166c-b5ba5e8a697c</li></ul></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/792ae02e-5ba3-13d1-8cc2-fd24a22f7f0b",
            "title" : "X",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/792ae02e-5ba3-13d1-8cc2-fd24a22f7f0b
            {
              "text" : "Battery of tests 'X' at 40°C/75% RH"
            },
            "specimen" : [
              {
                "reference" : "SpecimenDefinition/e95109ac-5ef9-1723-3506-2ef2f2e33d87"
              }
            ],
            "hasMember" : [
              // SpecimenDefinition/specimenDefStoredAt40
              {
                "reference" : "ObservationDefinition/1178fc31-0cfd-8c60-0b5b-9ae2850c6774"
              },
              // ObservationDefinition/Description
              {
                "reference" : "ObservationDefinition/186eb33e-a01d-4252-166c-b5ba5e8a697c"
              }
            ]
          }
        },
        // ObservationDefinition/Water
        {
          "fullUrl" : "urn:uuid:58cb0710-0ee6-1b7a-2a64-61a01df95ac2",
          "resource" : //  can have others
          {
            "resourceType" : "ObservationDefinition",
            "id" : "58cb0710-0ee6-1b7a-2a64-61a01df95ac2",
            "meta" : // accelerated40Y
            {
              "profile" : [
                🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/ObservationDefinition-test-method-drug-pq"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_58cb0710-0ee6-1b7a-2a64-61a01df95ac2\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"58cb0710-0ee6-1b7a-2a64-61a01df95ac2\"> </a><a name=\"hc58cb0710-0ee6-1b7a-2a64-61a01df95ac2\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;58cb0710-0ee6-1b7a-2a64-61a01df95ac2&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ObservationDefinition-test-method-drug-pq.html\">ObservationDefinition - Test Method PQ</a></p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/58cb0710-0ee6-1b7a-2a64-61a01df95ac2</code></p><p><b>title</b>: Y</p><p><b>status</b>: active</p><p><b>code</b>: Battery of tests 'Y' at 40°C/75% RH <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>specimen</b>: See on this page: SpecimenDefinition/e95109ac-5ef9-1723-3506-2ef2f2e33d87</p><p><b>hasMember</b>: See on this page: ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</p></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/58cb0710-0ee6-1b7a-2a64-61a01df95ac2",
            "title" : "Y",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/58cb0710-0ee6-1b7a-2a64-61a01df95ac2
            {
              "text" : "Battery of tests 'Y' at 40°C/75% RH"
            },
            "specimen" : [
              {
                "reference" : "SpecimenDefinition/e95109ac-5ef9-1723-3506-2ef2f2e33d87"
              }
            ],
            "hasMember" : [
              // SpecimenDefinition/specimenDefStoredAt40
              {
                "reference" : "ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e"
              }
            ]
          }
        },
        // ObservationDefinition/Microbiological
        {
          "fullUrl" : "urn:uuid:9bc183ee-6017-789b-8a6f-6a5c339f9ae0",
          "resource" : //  can have others
          {
            "resourceType" : "ObservationDefinition",
            "id" : "9bc183ee-6017-789b-8a6f-6a5c339f9ae0",
            "meta" : // accelerated40Z
            {
              "profile" : [
                🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/ObservationDefinition-test-method-drug-pq"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_9bc183ee-6017-789b-8a6f-6a5c339f9ae0\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"9bc183ee-6017-789b-8a6f-6a5c339f9ae0\"> </a><a name=\"hc9bc183ee-6017-789b-8a6f-6a5c339f9ae0\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;9bc183ee-6017-789b-8a6f-6a5c339f9ae0&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ObservationDefinition-test-method-drug-pq.html\">ObservationDefinition - Test Method PQ</a></p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/9bc183ee-6017-789b-8a6f-6a5c339f9ae0</code></p><p><b>title</b>: Z</p><p><b>status</b>: active</p><p><b>code</b>: Battery of tests 'Z' at 25°C/60% RH <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>specimen</b>: See on this page: SpecimenDefinition/e95109ac-5ef9-1723-3506-2ef2f2e33d87</p><p><b>hasMember</b>: See on this page: ObservationDefinition/ef781c18-8e86-7859-209b-469ee9ad42d8</p></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/9bc183ee-6017-789b-8a6f-6a5c339f9ae0",
            "title" : "Z",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/9bc183ee-6017-789b-8a6f-6a5c339f9ae0
            {
              "text" : "Battery of tests 'Z' at 25°C/60% RH"
            },
            "specimen" : [
              {
                "reference" : "SpecimenDefinition/e95109ac-5ef9-1723-3506-2ef2f2e33d87"
              }
            ],
            "hasMember" : [
              // SpecimenDefinition/specimenDefStoredAt40
              {
                "reference" : "ObservationDefinition/ef781c18-8e86-7859-209b-469ee9ad42d8"
              }
            ]
          }
        },
        // ObservationDefinition/Uniformity
        {
          "fullUrl" : "urn:uuid:b664977d-799d-a1ce-928a-5def2a9955bd",
          "resource" : {
            "resourceType" : "Specimen",
            "id" : "b664977d-799d-a1ce-928a-5def2a9955bd",
            "meta" : // id value="stabilityInitial-1"/
            // specimen-drug-pq-ex1
            {
              "profile" : [
                🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Specimen-drug-pq"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Specimen_b664977d-799d-a1ce-928a-5def2a9955bd\"> </a><p><b>Generated Narrative: Specimen</b><a name=\"b664977d-799d-a1ce-928a-5def2a9955bd\"> </a><a name=\"hcb664977d-799d-a1ce-928a-5def2a9955bd\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Specimen &quot;b664977d-799d-a1ce-928a-5def2a9955bd&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-Specimen-drug-pq.html\">Specimen - Drug PQ</a></p></div><h3>Collections</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Collected[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>2020-12-01</td></tr></table><blockquote><p><b>processing</b></p><p><b>description</b>: No storage</p></blockquote><blockquote><p><b>processing</b></p><p><b>description</b>: 25°C/60% RH</p></blockquote></div>"
            },
            "collection" : //  when sample first taken, before the timed periods start
            {
              "collectedDateTime" : "2020-12-01"
            },
            "processing" : [
              {
                "description" : "No storage"
              },
              {
                "description" : "25°C/60% RH"
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:b664977d-799d-a1ce-928a-5def2a9955be",
          "resource" : {
            "resourceType" : "Specimen",
            "id" : "b664977d-799d-a1ce-928a-5def2a9955be",
            "meta" : // stabilityInitial-2
            {
              "profile" : [
                🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Specimen-drug-pq"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Specimen_b664977d-799d-a1ce-928a-5def2a9955be\"> </a><p><b>Generated Narrative: Specimen</b><a name=\"b664977d-799d-a1ce-928a-5def2a9955be\"> </a><a name=\"hcb664977d-799d-a1ce-928a-5def2a9955be\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Specimen &quot;b664977d-799d-a1ce-928a-5def2a9955be&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-Specimen-drug-pq.html\">Specimen - Drug PQ</a></p></div><h3>Collections</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Collected[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>2020-12-02</td></tr></table><blockquote><p><b>processing</b></p><p><b>description</b>: No storage</p></blockquote><blockquote><p><b>processing</b></p><p><b>description</b>: 25°C/60% RH</p></blockquote></div>"
            },
            "collection" : //  when sample first taken, before the timed periods start
            {
              "collectedDateTime" : "2020-12-02"
            },
            "processing" : [
              {
                "description" : "No storage"
              },
              {
                "description" : "25°C/60% RH"
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:b664977d-799d-a1ce-928b-5def2a9955be",
          "resource" : {
            "resourceType" : "Specimen",
            "id" : "b664977d-799d-a1ce-928b-5def2a9955be",
            "meta" : // stabilityInitial-3
            {
              "profile" : [
                🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Specimen-drug-pq"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Specimen_b664977d-799d-a1ce-928b-5def2a9955be\"> </a><p><b>Generated Narrative: Specimen</b><a name=\"b664977d-799d-a1ce-928b-5def2a9955be\"> </a><a name=\"hcb664977d-799d-a1ce-928b-5def2a9955be\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Specimen &quot;b664977d-799d-a1ce-928b-5def2a9955be&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-Specimen-drug-pq.html\">Specimen - Drug PQ</a></p></div><h3>Collections</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Collected[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>2020-12-03</td></tr></table><blockquote><p><b>processing</b></p><p><b>description</b>: No storage</p></blockquote><blockquote><p><b>processing</b></p><p><b>description</b>: 25°C/60% RH</p></blockquote></div>"
            },
            "collection" : //  when sample first taken, before the timed periods start
            {
              "collectedDateTime" : "2020-12-03"
            },
            "processing" : [
              {
                "description" : "No storage"
              },
              {
                "description" : "25°C/60% RH"
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:6fabbf78-9678-8030-485f-b149956308d5",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "6fabbf78-9678-8030-485f-b149956308d5",
            "meta" : // id value="LongTerm25C-initial-1"/
            // observation-test-result-longterm25c-initial-1
            {
              "profile" : [
                🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Observation-test-result-drug-pq"
              ]
            },
            "text" : {
              "status" : "extensions",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_6fabbf78-9678-8030-485f-b149956308d5\"> </a><p><b>Generated Narrative: Observation</b><a name=\"6fabbf78-9678-8030-485f-b149956308d5\"> </a><a name=\"hc6fabbf78-9678-8030-485f-b149956308d5\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;6fabbf78-9678-8030-485f-b149956308d5&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-Observation-test-result-drug-pq.html\">Observation - Test Result Drug PQ</a></p></div><p><b>Triggered by</b>: See on this page: ActivityDefinition/4bfe1ee8-91ed-5c1b-3045-c749bb9d1d90</p><p><b>status</b>: final</p><p><b>code</b>: Test Components - Long-term 25C etc - Initial (XYZ) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>subject</b>: See on this page: Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</p><p><b>specimen</b>: See on this page: Specimen/b664977d-799d-a1ce-928a-5def2a9955bd</p><p><b>hasMember</b>: </p><ul><li><a name=\"hcLongTerm25C-initial-1-Description\"> </a></li><li><a name=\"hcobservation-test-result-lt25c-i1-degradation-imp1\"> </a></li><li><a name=\"hcLongTerm25C-initial-1-Degradation-imp2\"> </a></li><li><a name=\"hcLongTerm25C-initial-1-Degradation-imp3\"> </a></li><li><a name=\"hcLongTerm25C-initial-1-Degradation-impUnspecified\"> </a></li><li><a name=\"hcLongTerm25C-initial-1-Degradation-impTotal\"> </a></li><li><a name=\"hcLongTerm25C-initial-1-Water\"> </a></li><li><a name=\"hcLongTerm25C-initial-1-Microbiological\"> </a></li><li><a name=\"hcLongTerm25C-initial-1-Uniformity\"> </a></li></ul><blockquote><p/><p><a name=\"LongTerm25C-initial-1-Description\"> </a></p><p><a name=\"hcLongTerm25C-initial-1-Description\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/1178fc31-0cfd-8c60-0b5b-9ae2850c6774</p><p><b>status</b>: final</p><p><b>code</b>: Description <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DESC)</span></p><p><b>subject</b>: See on this page: Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><blockquote><p/><p><a name=\"observation-test-result-lt25c-i1-degradation-imp1\"> </a></p><p><a name=\"hcobservation-test-result-lt25c-i1-degradation-imp1\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</p><p><b>value</b>: 0.101 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 1 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p/><p><a name=\"LongTerm25C-initial-1-Degradation-imp2\"> </a></p><p><a name=\"hcLongTerm25C-initial-1-Degradation-imp2\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</p><p><b>value</b>: 0.201 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 2 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p/><p><a name=\"LongTerm25C-initial-1-Degradation-imp3\"> </a></p><p><a name=\"hcLongTerm25C-initial-1-Degradation-imp3\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</p><p><b>value</b>: 0.201 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 3 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p/><p><a name=\"LongTerm25C-initial-1-Degradation-impUnspecified\"> </a></p><p><a name=\"hcLongTerm25C-initial-1-Degradation-impUnspecified\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</p><p><b>value</b>: &lt;0.101 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Any Unspecified Degradation Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p/><p><a name=\"LongTerm25C-initial-1-Degradation-impTotal\"> </a></p><p><a name=\"hcLongTerm25C-initial-1-Degradation-impTotal\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</p><p><b>value</b>: 0.801 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Total Degradation Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p/><p><a name=\"LongTerm25C-initial-1-Water\"> </a></p><p><a name=\"hcLongTerm25C-initial-1-Water\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/186eb33e-a01d-4252-166c-b5ba5e8a697c</p><p><b>status</b>: final</p><p><b>code</b>: Water Content <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#WaterContent)</span></p><p><b>subject</b>: See on this page: Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</p><p><b>value</b>: 0.1501 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p></blockquote><blockquote><p/><p><a name=\"LongTerm25C-initial-1-Microbiological\"> </a></p><p><a name=\"hcLongTerm25C-initial-1-Microbiological\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</p><p><b>status</b>: final</p><p><b>code</b>: Microbiological Quality <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Microbiological Quality)</span></p><p><b>subject</b>: See on this page: Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><blockquote><p/><p><a name=\"LongTerm25C-initial-1-Uniformity\"> </a></p><p><a name=\"hcLongTerm25C-initial-1-Uniformity\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/ef781c18-8e86-7859-209b-469ee9ad42d8</p><p><b>status</b>: final</p><p><b>code</b>: Uniformity of dosage units (by weight) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#uniformity-dosage)</span></p><p><b>subject</b>: See on this page: Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm25C-initial-1-Description</b><a name=\"LongTerm25C-initial-1-Description\"> </a><a name=\"hcLongTerm25C-initial-1-Description\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_1178fc31-0cfd-8c60-0b5b-9ae2850c6774\">ObservationDefinition/1178fc31-0cfd-8c60-0b5b-9ae2850c6774</a></p><p><b>status</b>: final</p><p><b>code</b>: Description <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DESC)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#Medication_7ef62d57-7cc6-9211-66d6-abc7e096093c\">Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-product-impurities-pq-ex1.html#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</a></p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #observation-test-result-lt25c-i1-degradation-imp1</b><a name=\"observation-test-result-lt25c-i1-degradation-imp1\"> </a><a name=\"hcobservation-test-result-lt25c-i1-degradation-imp1\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_2c5683d6-6e94-825b-056a-129a04c95e2f\">ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f</a></p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#Medication_7ef62d57-7cc6-9211-66d6-abc7e096093c\">Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-product-impurities-pq-ex1.html#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</a></p><p><b>value</b>: 0.101 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 1 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm25C-initial-1-Degradation-imp2</b><a name=\"LongTerm25C-initial-1-Degradation-imp2\"> </a><a name=\"hcLongTerm25C-initial-1-Degradation-imp2\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_2c5683d6-6e94-825b-056a-129a04c95e2f\">ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f</a></p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#Medication_7ef62d57-7cc6-9211-66d6-abc7e096093c\">Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-product-impurities-pq-ex1.html#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</a></p><p><b>value</b>: 0.201 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 2 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm25C-initial-1-Degradation-imp3</b><a name=\"LongTerm25C-initial-1-Degradation-imp3\"> </a><a name=\"hcLongTerm25C-initial-1-Degradation-imp3\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_2c5683d6-6e94-825b-056a-129a04c95e2f\">ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f</a></p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#Medication_7ef62d57-7cc6-9211-66d6-abc7e096093c\">Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-product-impurities-pq-ex1.html#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</a></p><p><b>value</b>: 0.201 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 3 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm25C-initial-1-Degradation-impUnspecified</b><a name=\"LongTerm25C-initial-1-Degradation-impUnspecified\"> </a><a name=\"hcLongTerm25C-initial-1-Degradation-impUnspecified\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_2c5683d6-6e94-825b-056a-129a04c95e2f\">ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f</a></p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#Medication_7ef62d57-7cc6-9211-66d6-abc7e096093c\">Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-product-impurities-pq-ex1.html#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</a></p><p><b>value</b>: &lt;0.101 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Any Unspecified Degradation Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm25C-initial-1-Degradation-impTotal</b><a name=\"LongTerm25C-initial-1-Degradation-impTotal\"> </a><a name=\"hcLongTerm25C-initial-1-Degradation-impTotal\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_2c5683d6-6e94-825b-056a-129a04c95e2f\">ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f</a></p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#Medication_7ef62d57-7cc6-9211-66d6-abc7e096093c\">Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-product-impurities-pq-ex1.html#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</a></p><p><b>value</b>: 0.801 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Total Degradation Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm25C-initial-1-Water</b><a name=\"LongTerm25C-initial-1-Water\"> </a><a name=\"hcLongTerm25C-initial-1-Water\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_186eb33e-a01d-4252-166c-b5ba5e8a697c\">ObservationDefinition/186eb33e-a01d-4252-166c-b5ba5e8a697c</a></p><p><b>status</b>: final</p><p><b>code</b>: Water Content <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#WaterContent)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#Medication_7ef62d57-7cc6-9211-66d6-abc7e096093c\">Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-product-impurities-pq-ex1.html#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</a></p><p><b>value</b>: 0.1501 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm25C-initial-1-Microbiological</b><a name=\"LongTerm25C-initial-1-Microbiological\"> </a><a name=\"hcLongTerm25C-initial-1-Microbiological\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_73d9d304-a0b8-31b6-1165-346563b9305e\">ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</a></p><p><b>status</b>: final</p><p><b>code</b>: Microbiological Quality <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Microbiological Quality)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#Medication_7ef62d57-7cc6-9211-66d6-abc7e096093c\">Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-product-impurities-pq-ex1.html#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</a></p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm25C-initial-1-Uniformity</b><a name=\"LongTerm25C-initial-1-Uniformity\"> </a><a name=\"hcLongTerm25C-initial-1-Uniformity\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_ef781c18-8e86-7859-209b-469ee9ad42d8\">ObservationDefinition/ef781c18-8e86-7859-209b-469ee9ad42d8</a></p><p><b>status</b>: final</p><p><b>code</b>: Uniformity of dosage units (by weight) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#uniformity-dosage)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#Medication_7ef62d57-7cc6-9211-66d6-abc7e096093c\">Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-product-impurities-pq-ex1.html#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</a></p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote></div>"
            },
            "contained" : [
              {
                "resourceType" : "Observation",
                "id" : "LongTerm25C-initial-1-Description",
                "meta" : {
                  "profile" : [
                    🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Observation-test-result-drug-pq"
                  ]
                },
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/1178fc31-0cfd-8c60-0b5b-9ae2850c6774"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Description
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "DESC",
                      "display" : "Description"
                    }
                  ],
                  "text" : "Description"
                },
                "subject" : {
                  "reference" : "Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Medication/medication-batch-information-drug-pq-ex1
                  {
                    "reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
                  }
                ],
                "valueCodeableConcept" : // Organization/tester
                {
                  "text" : "Complies"
                }
              },
              {
                "resourceType" : "Observation",
                "id" : "observation-test-result-lt25c-i1-degradation-imp1",
                "meta" : {
                  "profile" : [
                    🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Observation-test-result-drug-pq"
                  ]
                },
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Degradation
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "DGP",
                      "display" : "Degradation Products"
                    }
                  ],
                  "text" : "Degradation Products"
                },
                "subject" : {
                  "reference" : "Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Medication/medication-batch-information-drug-pq-ex1
                  {
                    "reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
                  }
                ],
                "valueQuantity" : // Organization/tester
                {
                  "value" : 0.101,
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                },
                "component" : [
                  {
                    "code" : {
                      "coding" : [
                        {
                          "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                          "code" : "IMP",
                          "display" : "Impurity"
                        }
                      ]
                    },
                    "valueCodeableConcept" : {
                      "text" : "Impurity 1"
                    }
                  }
                ]
              },
              //  could have the code of an impurity substance, or could have an extension to point to it as a resource
              {
                "resourceType" : "Observation",
                "id" : "LongTerm25C-initial-1-Degradation-imp2",
                "meta" : {
                  "profile" : [
                    🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Observation-test-result-drug-pq"
                  ]
                },
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Degradation
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "DGP",
                      "display" : "Degradation Products"
                    }
                  ],
                  "text" : "Degradation Products"
                },
                "subject" : {
                  "reference" : "Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Medication/medication-batch-information-drug-pq-ex1
                  {
                    "reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
                  }
                ],
                "valueQuantity" : // Organization/tester
                {
                  "value" : 0.201,
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                },
                "component" : [
                  {
                    "code" : {
                      "coding" : [
                        {
                          "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                          "code" : "IMP",
                          "display" : "Impurity"
                        }
                      ]
                    },
                    "valueCodeableConcept" : {
                      "text" : "Impurity 2"
                    }
                  }
                ]
              },
              {
                "resourceType" : "Observation",
                "id" : "LongTerm25C-initial-1-Degradation-imp3",
                "meta" : {
                  "profile" : [
                    🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Observation-test-result-drug-pq"
                  ]
                },
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Degradation
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "DGP",
                      "display" : "Degradation Products"
                    }
                  ],
                  "text" : "Degradation Products"
                },
                "subject" : {
                  "reference" : "Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Medication/medication-batch-information-drug-pq-ex1
                  {
                    "reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
                  }
                ],
                "valueQuantity" : // Organization/tester
                {
                  "value" : 0.201,
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                },
                "component" : [
                  {
                    "code" : {
                      "coding" : [
                        {
                          "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                          "code" : "IMP",
                          "display" : "Impurity"
                        }
                      ]
                    },
                    "valueCodeableConcept" : {
                      "text" : "Impurity 3"
                    }
                  }
                ]
              },
              {
                "resourceType" : "Observation",
                "id" : "LongTerm25C-initial-1-Degradation-impUnspecified",
                "meta" : {
                  "profile" : [
                    🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Observation-test-result-drug-pq"
                  ]
                },
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Degradation
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "DGP",
                      "display" : "Degradation Products"
                    }
                  ],
                  "text" : "Degradation Products"
                },
                "subject" : {
                  "reference" : "Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Medication/medication-batch-information-drug-pq-ex1
                  {
                    "reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
                  }
                ],
                "valueQuantity" : // Organization/tester
                {
                  "value" : 0.101,
                  "comparator" : "<",
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                },
                "component" : [
                  {
                    "code" : {
                      "coding" : [
                        {
                          "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                          "code" : "IMP",
                          "display" : "Impurity"
                        }
                      ]
                    },
                    "valueCodeableConcept" : {
                      "text" : "Any Unspecified Degradation Impurity"
                    }
                  }
                ]
              },
              {
                "resourceType" : "Observation",
                "id" : "LongTerm25C-initial-1-Degradation-impTotal",
                "meta" : {
                  "profile" : [
                    🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Observation-test-result-drug-pq"
                  ]
                },
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Degradation
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "DGP",
                      "display" : "Degradation Products"
                    }
                  ],
                  "text" : "Degradation Products"
                },
                "subject" : {
                  "reference" : "Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Medication/medication-batch-information-drug-pq-ex1
                  {
                    "reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
                  }
                ],
                "valueQuantity" : // Organization/tester
                {
                  "value" : 0.801,
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                },
                "component" : [
                  {
                    "code" : {
                      "coding" : [
                        {
                          "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                          "code" : "IMP",
                          "display" : "Impurity"
                        }
                      ]
                    },
                    "valueCodeableConcept" : {
                      "text" : "Total Degradation Impurities"
                    }
                  }
                ]
              },
              {
                "resourceType" : "Observation",
                "id" : "LongTerm25C-initial-1-Water",
                "meta" : {
                  "profile" : [
                    🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Observation-test-result-drug-pq"
                  ]
                },
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/186eb33e-a01d-4252-166c-b5ba5e8a697c"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Water
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "WaterContent",
                      "display" : "Water Content"
                    }
                  ]
                },
                "subject" : {
                  "reference" : "Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Medication/medication-batch-information-drug-pq-ex1
                  {
                    "reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
                  }
                ],
                "valueQuantity" : // Organization/tester
                {
                  "value" : 0.1501,
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                }
              },
              {
                "resourceType" : "Observation",
                "id" : "LongTerm25C-initial-1-Microbiological",
                "meta" : {
                  "profile" : [
                    🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Observation-test-result-drug-pq"
                  ]
                },
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Microbiological
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Microbiological Quality",
                      "display" : "Microbiological Quality"
                    }
                  ]
                },
                "subject" : {
                  "reference" : "Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Medication/medication-batch-information-drug-pq-ex1
                  {
                    "reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
                  }
                ],
                "valueCodeableConcept" : // Organization/tester
                {
                  "text" : "Complies"
                }
              },
              {
                "resourceType" : "Observation",
                "id" : "LongTerm25C-initial-1-Uniformity",
                "meta" : {
                  "profile" : [
                    🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Observation-test-result-drug-pq"
                  ]
                },
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/ef781c18-8e86-7859-209b-469ee9ad42d8"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Uniformity
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "uniformity-dosage",
                      "display" : "Uniformity of dosage units (by weight)"
                    }
                  ]
                },
                "subject" : {
                  "reference" : "Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Medication/medication-batch-information-drug-pq-ex1
                  {
                    "reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
                  }
                ],
                "valueCodeableConcept" : // Organization/tester
                {
                  "text" : "Complies"
                }
              }
            ],
            "extension" : [
              {
                "url" : "http://hl7.org/fhir/StructureDefinition/workflow-triggeredBy",
                "valueReference" : {
                  "reference" : "ActivityDefinition/4bfe1ee8-91ed-5c1b-3045-c749bb9d1d90"
                }
              }
            ],
            "status" : "final",
            "code" : // ActivityDefinition/activitydefinition-test-drug-pq-ex1
            {
              "text" : "Test Components - Long-term 25C etc - Initial (XYZ)"
            },
            "subject" : {
              "reference" : "Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Medication/medication-batch-information-drug-pq-ex1
              {
                "reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
              }
            ],
            "specimen" : // Organization/tester
            {
              "reference" : "Specimen/b664977d-799d-a1ce-928a-5def2a9955bd"
            },
            "hasMember" : [
              // Specimen/specimen-drug-pq-ex1
              {
                "reference" : "#LongTerm25C-initial-1-Description"
              },
              {
                "reference" : "#observation-test-result-lt25c-i1-degradation-imp1"
              },
              {
                "reference" : "#LongTerm25C-initial-1-Degradation-imp2"
              },
              {
                "reference" : "#LongTerm25C-initial-1-Degradation-imp3"
              },
              {
                "reference" : "#LongTerm25C-initial-1-Degradation-impUnspecified"
              },
              {
                "reference" : "#LongTerm25C-initial-1-Degradation-impTotal"
              },
              {
                "reference" : "#LongTerm25C-initial-1-Water"
              },
              {
                "reference" : "#LongTerm25C-initial-1-Microbiological"
              },
              {
                "reference" : "#LongTerm25C-initial-1-Uniformity"
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:74535cc6-5232-5ab5-81cf-167a480795e5",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "74535cc6-5232-5ab5-81cf-167a480795e5",
            "text" : // LongTerm25C-initial-2
            {
              "status" : "extensions",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_74535cc6-5232-5ab5-81cf-167a480795e5\"> </a><p><b>Generated Narrative: Observation</b><a name=\"74535cc6-5232-5ab5-81cf-167a480795e5\"> </a><a name=\"hc74535cc6-5232-5ab5-81cf-167a480795e5\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;74535cc6-5232-5ab5-81cf-167a480795e5&quot; </p></div><p><b>Triggered by</b>: See on this page: ActivityDefinition/4bfe1ee8-91ed-5c1b-3045-c749bb9d1d90</p><p><b>status</b>: final</p><p><b>code</b>: Test Components - Long-term 25C etc - Initial (XYZ) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>subject</b>: See on this page: Medication/8306cfc5-158f-1a53-a683-048b226060d9</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</p><p><b>specimen</b>: See on this page: Specimen/b664977d-799d-a1ce-928a-5def2a9955be</p><p><b>hasMember</b>: </p><ul><li><a name=\"hcLongTerm25C-initial-2-Description\"> </a></li><li><a name=\"hcLongTerm25C-initial-2-Degradation\"> </a></li><li><a name=\"hcLongTerm25C-initial-2-Microbiological\"> </a></li><li><a name=\"hcLongTerm25C-initial-2-Uniformity\"> </a></li></ul><blockquote><p/><p><a name=\"LongTerm25C-initial-2-Description\"> </a></p><p><a name=\"hcLongTerm25C-initial-2-Description\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/1178fc31-0cfd-8c60-0b5b-9ae2850c6774</p><p><b>status</b>: final</p><p><b>code</b>: Description <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DESC)</span></p><p><b>subject</b>: See on this page: Medication/8306cfc5-158f-1a53-a683-048b226060d9</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><blockquote><p/><p><a name=\"LongTerm25C-initial-2-Degradation\"> </a></p><p><a name=\"hcLongTerm25C-initial-2-Degradation\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/8306cfc5-158f-1a53-a683-048b226060d9</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</p><p><b>value</b>: 0.1 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p></blockquote><blockquote><p/><p><a name=\"LongTerm25C-initial-2-Microbiological\"> </a></p><p><a name=\"hcLongTerm25C-initial-2-Microbiological\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</p><p><b>status</b>: final</p><p><b>code</b>: Microbiological Quality <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Microbiological Quality)</span></p><p><b>subject</b>: See on this page: Medication/8306cfc5-158f-1a53-a683-048b226060d9</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</p><p><b>value</b>: Complies</p></blockquote><blockquote><p/><p><a name=\"LongTerm25C-initial-2-Uniformity\"> </a></p><p><a name=\"hcLongTerm25C-initial-2-Uniformity\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/ef781c18-8e86-7859-209b-469ee9ad42d8</p><p><b>status</b>: final</p><p><b>code</b>: Uniformity of dosage units (by weight) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#uniformity-dosage)</span></p><p><b>subject</b>: See on this page: Medication/8306cfc5-158f-1a53-a683-048b226060d9</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm25C-initial-2-Description</b><a name=\"LongTerm25C-initial-2-Description\"> </a><a name=\"hcLongTerm25C-initial-2-Description\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_1178fc31-0cfd-8c60-0b5b-9ae2850c6774\">ObservationDefinition/1178fc31-0cfd-8c60-0b5b-9ae2850c6774</a></p><p><b>status</b>: final</p><p><b>code</b>: Description <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DESC)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#Medication_8306cfc5-158f-1a53-a683-048b226060d9\">Medication/8306cfc5-158f-1a53-a683-048b226060d9</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-product-impurities-pq-ex1.html#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</a></p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm25C-initial-2-Degradation</b><a name=\"LongTerm25C-initial-2-Degradation\"> </a><a name=\"hcLongTerm25C-initial-2-Degradation\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_2c5683d6-6e94-825b-056a-129a04c95e2f\">ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f</a></p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#Medication_8306cfc5-158f-1a53-a683-048b226060d9\">Medication/8306cfc5-158f-1a53-a683-048b226060d9</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-product-impurities-pq-ex1.html#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</a></p><p><b>value</b>: 0.1 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm25C-initial-2-Microbiological</b><a name=\"LongTerm25C-initial-2-Microbiological\"> </a><a name=\"hcLongTerm25C-initial-2-Microbiological\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_73d9d304-a0b8-31b6-1165-346563b9305e\">ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</a></p><p><b>status</b>: final</p><p><b>code</b>: Microbiological Quality <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Microbiological Quality)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#Medication_8306cfc5-158f-1a53-a683-048b226060d9\">Medication/8306cfc5-158f-1a53-a683-048b226060d9</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-product-impurities-pq-ex1.html#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</a></p><p><b>value</b>: Complies</p></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm25C-initial-2-Uniformity</b><a name=\"LongTerm25C-initial-2-Uniformity\"> </a><a name=\"hcLongTerm25C-initial-2-Uniformity\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_ef781c18-8e86-7859-209b-469ee9ad42d8\">ObservationDefinition/ef781c18-8e86-7859-209b-469ee9ad42d8</a></p><p><b>status</b>: final</p><p><b>code</b>: Uniformity of dosage units (by weight) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#uniformity-dosage)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#Medication_8306cfc5-158f-1a53-a683-048b226060d9\">Medication/8306cfc5-158f-1a53-a683-048b226060d9</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-product-impurities-pq-ex1.html#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</a></p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote></div>"
            },
            "contained" : [
              {
                "resourceType" : "Observation",
                "id" : "LongTerm25C-initial-2-Description",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/1178fc31-0cfd-8c60-0b5b-9ae2850c6774"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Description
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "DESC",
                      "display" : "Description"
                    }
                  ],
                  "text" : "Description"
                },
                "subject" : {
                  "reference" : "Medication/8306cfc5-158f-1a53-a683-048b226060d9"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Medication/medication-actual-batch-2
                  {
                    "reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
                  }
                ],
                "valueCodeableConcept" : // Organization/tester
                {
                  "text" : "Complies"
                }
              },
              {
                "resourceType" : "Observation",
                "id" : "LongTerm25C-initial-2-Degradation",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Degradation
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "DGP",
                      "display" : "Degradation Products"
                    }
                  ],
                  "text" : "Degradation Products"
                },
                "subject" : {
                  "reference" : "Medication/8306cfc5-158f-1a53-a683-048b226060d9"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Medication/medication-actual-batch-2
                  {
                    "reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
                  }
                ],
                "valueQuantity" : // Organization/tester
                {
                  "value" : 0.1,
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                }
              },
              {
                "resourceType" : "Observation",
                "id" : "LongTerm25C-initial-2-Microbiological",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Microbiological
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Microbiological Quality",
                      "display" : "Microbiological Quality"
                    }
                  ]
                },
                "subject" : {
                  "reference" : "Medication/8306cfc5-158f-1a53-a683-048b226060d9"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Medication/medication-actual-batch-2
                  {
                    "reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
                  }
                ],
                "valueString" : "Complies"
              },
              // Organization/tester
              {
                "resourceType" : "Observation",
                "id" : "LongTerm25C-initial-2-Uniformity",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/ef781c18-8e86-7859-209b-469ee9ad42d8"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Uniformity
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "uniformity-dosage",
                      "display" : "Uniformity of dosage units (by weight)"
                    }
                  ]
                },
                "subject" : {
                  "reference" : "Medication/8306cfc5-158f-1a53-a683-048b226060d9"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Medication/medication-actual-batch-2
                  {
                    "reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
                  }
                ],
                "valueCodeableConcept" : // Organization/tester
                {
                  "text" : "Complies"
                }
              }
            ],
            "extension" : [
              //  use a standard extension to say what plan this is being done for. However it doesn't link to the step of that plan
                         that would mean using sub-ActivityDefintions probably
              {
                "url" : "http://hl7.org/fhir/StructureDefinition/workflow-triggeredBy",
                "valueReference" : {
                  "reference" : "ActivityDefinition/4bfe1ee8-91ed-5c1b-3045-c749bb9d1d90"
                }
              }
            ],
            "status" : "final",
            "code" : // ActivityDefinition/activitydefinition-test-drug-pq-ex1
            {
              "text" : "Test Components - Long-term 25C etc - Initial (XYZ)"
            },
            "subject" : {
              "reference" : "Medication/8306cfc5-158f-1a53-a683-048b226060d9"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Medication/medication-actual-batch-2
              {
                "reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
              }
            ],
            "specimen" : // Organization/tester
            {
              "reference" : "Specimen/b664977d-799d-a1ce-928a-5def2a9955be"
            },
            "hasMember" : [
              // Specimen/stabilityInitial-2
              {
                "reference" : "#LongTerm25C-initial-2-Description"
              },
              {
                "reference" : "#LongTerm25C-initial-2-Degradation"
              },
              {
                "reference" : "#LongTerm25C-initial-2-Microbiological"
              },
              {
                "reference" : "#LongTerm25C-initial-2-Uniformity"
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:8bf75da1-9221-66fe-6725-c64cb45a57e6",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "8bf75da1-9221-66fe-6725-c64cb45a57e6",
            "text" : // LongTerm25C-initial-3
            {
              "status" : "extensions",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_8bf75da1-9221-66fe-6725-c64cb45a57e6\"> </a><p><b>Generated Narrative: Observation</b><a name=\"8bf75da1-9221-66fe-6725-c64cb45a57e6\"> </a><a name=\"hc8bf75da1-9221-66fe-6725-c64cb45a57e6\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;8bf75da1-9221-66fe-6725-c64cb45a57e6&quot; </p></div><p><b>Triggered by</b>: See on this page: ActivityDefinition/4bfe1ee8-91ed-5c1b-3045-c749bb9d1d90</p><p><b>status</b>: final</p><p><b>code</b>: Test Components - Long-term 25C etc - Initial (XYZ) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>subject</b>: See on this page: Medication/f54d4666-7ae3-4e30-8c5a-6d13838c4f3b</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</p><p><b>specimen</b>: See on this page: Specimen/b664977d-799d-a1ce-928b-5def2a9955be</p><p><b>hasMember</b>: </p><ul><li><a name=\"hcLongTerm25C-initial-3-Description\"> </a></li><li><a name=\"hcLongTerm25C-initial-3-Degradation\"> </a></li><li><a name=\"hcLongTerm25C-initial-3-Microbiological\"> </a></li><li><a name=\"hcLongTerm25C-initial-3-Uniformity\"> </a></li></ul><blockquote><p/><p><a name=\"LongTerm25C-initial-3-Description\"> </a></p><p><a name=\"hcLongTerm25C-initial-3-Description\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/1178fc31-0cfd-8c60-0b5b-9ae2850c6774</p><p><b>status</b>: final</p><p><b>code</b>: Description <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DESC)</span></p><p><b>subject</b>: See on this page: Medication/f54d4666-7ae3-4e30-8c5a-6d13838c4f3b</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><blockquote><p/><p><a name=\"LongTerm25C-initial-3-Degradation\"> </a></p><p><a name=\"hcLongTerm25C-initial-3-Degradation\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/f54d4666-7ae3-4e30-8c5a-6d13838c4f3b</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</p><p><b>value</b>: 0.1 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p></blockquote><blockquote><p/><p><a name=\"LongTerm25C-initial-3-Microbiological\"> </a></p><p><a name=\"hcLongTerm25C-initial-3-Microbiological\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</p><p><b>status</b>: final</p><p><b>code</b>: Microbiological Quality <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Microbiological Quality)</span></p><p><b>subject</b>: See on this page: Medication/f54d4666-7ae3-4e30-8c5a-6d13838c4f3b</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><blockquote><p/><p><a name=\"LongTerm25C-initial-3-Uniformity\"> </a></p><p><a name=\"hcLongTerm25C-initial-3-Uniformity\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/ef781c18-8e86-7859-209b-469ee9ad42d8</p><p><b>status</b>: final</p><p><b>code</b>: Uniformity of dosage units (by weight) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#uniformity-dosage)</span></p><p><b>subject</b>: See on this page: Medication/f54d4666-7ae3-4e30-8c5a-6d13838c4f3b</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm25C-initial-3-Description</b><a name=\"LongTerm25C-initial-3-Description\"> </a><a name=\"hcLongTerm25C-initial-3-Description\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_1178fc31-0cfd-8c60-0b5b-9ae2850c6774\">ObservationDefinition/1178fc31-0cfd-8c60-0b5b-9ae2850c6774</a></p><p><b>status</b>: final</p><p><b>code</b>: Description <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DESC)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#Medication_f54d4666-7ae3-4e30-8c5a-6d13838c4f3b\">Medication/f54d4666-7ae3-4e30-8c5a-6d13838c4f3b</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-product-impurities-pq-ex1.html#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</a></p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm25C-initial-3-Degradation</b><a name=\"LongTerm25C-initial-3-Degradation\"> </a><a name=\"hcLongTerm25C-initial-3-Degradation\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_2c5683d6-6e94-825b-056a-129a04c95e2f\">ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f</a></p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#Medication_f54d4666-7ae3-4e30-8c5a-6d13838c4f3b\">Medication/f54d4666-7ae3-4e30-8c5a-6d13838c4f3b</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-product-impurities-pq-ex1.html#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</a></p><p><b>value</b>: 0.1 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm25C-initial-3-Microbiological</b><a name=\"LongTerm25C-initial-3-Microbiological\"> </a><a name=\"hcLongTerm25C-initial-3-Microbiological\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_73d9d304-a0b8-31b6-1165-346563b9305e\">ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</a></p><p><b>status</b>: final</p><p><b>code</b>: Microbiological Quality <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Microbiological Quality)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#Medication_f54d4666-7ae3-4e30-8c5a-6d13838c4f3b\">Medication/f54d4666-7ae3-4e30-8c5a-6d13838c4f3b</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-product-impurities-pq-ex1.html#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</a></p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm25C-initial-3-Uniformity</b><a name=\"LongTerm25C-initial-3-Uniformity\"> </a><a name=\"hcLongTerm25C-initial-3-Uniformity\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_ef781c18-8e86-7859-209b-469ee9ad42d8\">ObservationDefinition/ef781c18-8e86-7859-209b-469ee9ad42d8</a></p><p><b>status</b>: final</p><p><b>code</b>: Uniformity of dosage units (by weight) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#uniformity-dosage)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#Medication_f54d4666-7ae3-4e30-8c5a-6d13838c4f3b\">Medication/f54d4666-7ae3-4e30-8c5a-6d13838c4f3b</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-product-impurities-pq-ex1.html#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</a></p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote></div>"
            },
            "contained" : [
              {
                "resourceType" : "Observation",
                "id" : "LongTerm25C-initial-3-Description",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/1178fc31-0cfd-8c60-0b5b-9ae2850c6774"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Description
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "DESC",
                      "display" : "Description"
                    }
                  ],
                  "text" : "Description"
                },
                "subject" : {
                  "reference" : "Medication/f54d4666-7ae3-4e30-8c5a-6d13838c4f3b"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Medication/medication-actual-batch-3
                  {
                    "reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
                  }
                ],
                "valueCodeableConcept" : // Organization/tester
                {
                  "text" : "Complies"
                }
              },
              {
                "resourceType" : "Observation",
                "id" : "LongTerm25C-initial-3-Degradation",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Degradation
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "DGP",
                      "display" : "Degradation Products"
                    }
                  ],
                  "text" : "Degradation Products"
                },
                "subject" : {
                  "reference" : "Medication/f54d4666-7ae3-4e30-8c5a-6d13838c4f3b"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Medication/medication-actual-batch-3
                  {
                    "reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
                  }
                ],
                "valueQuantity" : // Organization/tester
                {
                  "value" : 0.1,
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                }
              },
              {
                "resourceType" : "Observation",
                "id" : "LongTerm25C-initial-3-Microbiological",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Microbiological
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Microbiological Quality",
                      "display" : "Microbiological Quality"
                    }
                  ]
                },
                "subject" : {
                  "reference" : "Medication/f54d4666-7ae3-4e30-8c5a-6d13838c4f3b"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Medication/medication-actual-batch-3
                  {
                    "reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
                  }
                ],
                "valueCodeableConcept" : // Organization/tester
                {
                  "text" : "Complies"
                }
              },
              {
                "resourceType" : "Observation",
                "id" : "LongTerm25C-initial-3-Uniformity",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/ef781c18-8e86-7859-209b-469ee9ad42d8"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Uniformity
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "uniformity-dosage",
                      "display" : "Uniformity of dosage units (by weight)"
                    }
                  ]
                },
                "subject" : {
                  "reference" : "Medication/f54d4666-7ae3-4e30-8c5a-6d13838c4f3b"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Medication/medication-actual-batch-3
                  {
                    "reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
                  }
                ],
                "valueCodeableConcept" : // Organization/tester
                {
                  "text" : "Complies"
                }
              }
            ],
            "extension" : [
              //  use a standard extension to say what plan this is being done for. However it doesn't link to the step of that plan
                         that would mean using sub-ActivityDefintions probably
              {
                "url" : "http://hl7.org/fhir/StructureDefinition/workflow-triggeredBy",
                "valueReference" : {
                  "reference" : "ActivityDefinition/4bfe1ee8-91ed-5c1b-3045-c749bb9d1d90"
                }
              }
            ],
            "status" : "final",
            "code" : // ActivityDefinition/activitydefinition-test-drug-pq-ex1
            {
              "text" : "Test Components - Long-term 25C etc - Initial (XYZ)"
            },
            "subject" : {
              "reference" : "Medication/f54d4666-7ae3-4e30-8c5a-6d13838c4f3b"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Medication/medication-actual-batch-3
              {
                "reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
              }
            ],
            "specimen" : // Organization/tester
            {
              "reference" : "Specimen/b664977d-799d-a1ce-928b-5def2a9955be"
            },
            "hasMember" : [
              // Specimen/stabilityInitial-3
              {
                "reference" : "#LongTerm25C-initial-3-Description"
              },
              {
                "reference" : "#LongTerm25C-initial-3-Degradation"
              },
              {
                "reference" : "#LongTerm25C-initial-3-Microbiological"
              },
              {
                "reference" : "#LongTerm25C-initial-3-Uniformity"
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:18826818-10c4-972c-618e-01694ff06c78",
          "resource" : {
            "resourceType" : "Specimen",
            "id" : "18826818-10c4-972c-618e-01694ff06c78",
            "text" : // stability18months-1
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Specimen_18826818-10c4-972c-618e-01694ff06c78\"> </a><p><b>Generated Narrative: Specimen</b><a name=\"18826818-10c4-972c-618e-01694ff06c78\"> </a><a name=\"hc18826818-10c4-972c-618e-01694ff06c78\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Specimen &quot;18826818-10c4-972c-618e-01694ff06c78&quot; </p></div><h3>Collections</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Collected[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>2020-12-01</td></tr></table><blockquote><p><b>processing</b></p><p><b>description</b>: Store for 18 months</p><p><b>time</b>: 2020-12 --&gt; 2022-06</p></blockquote><blockquote><p><b>processing</b></p><p><b>description</b>: 25°C/60% RH</p></blockquote></div>"
            },
            "collection" : //  when sample first taken, before the timed periods start
            {
              "collectedDateTime" : "2020-12-01"
            },
            "processing" : [
              {
                "description" : "Store for 18 months",
                "timePeriod" : //  18 months
                {
                  "extension" : [
                    {
                      "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-storage-duration-pq",
                      "valueDuration" : {
                        "value" : 18,
                        "unit" : "month"
                      }
                    }
                  ],
                  "start" : "2020-12",
                  "end" : "2022-06"
                }
              },
              {
                "description" : "25°C/60% RH"
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:18826818-10c4-972c-618e-01694ff06c88",
          "resource" : {
            "resourceType" : "Specimen",
            "id" : "18826818-10c4-972c-618e-01694ff06c88",
            "text" : // stability18months-2
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Specimen_18826818-10c4-972c-618e-01694ff06c88\"> </a><p><b>Generated Narrative: Specimen</b><a name=\"18826818-10c4-972c-618e-01694ff06c88\"> </a><a name=\"hc18826818-10c4-972c-618e-01694ff06c88\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Specimen &quot;18826818-10c4-972c-618e-01694ff06c88&quot; </p></div><h3>Collections</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Collected[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>2020-12-02</td></tr></table><blockquote><p><b>processing</b></p><p><b>description</b>: Store for 18 months</p><p><b>time</b>: 2020-12 --&gt; 2022-06</p></blockquote><blockquote><p><b>processing</b></p><p><b>description</b>: 25°C/60% RH</p></blockquote></div>"
            },
            "collection" : //  when sample first taken, before the timed periods start
            {
              "collectedDateTime" : "2020-12-02"
            },
            "processing" : [
              {
                "description" : "Store for 18 months",
                "timePeriod" : //  18 months
                {
                  "extension" : [
                    {
                      "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-storage-duration-pq",
                      "valueDuration" : {
                        "value" : 18,
                        "unit" : "month"
                      }
                    }
                  ],
                  "start" : "2020-12",
                  "end" : "2022-06"
                }
              },
              {
                "description" : "25°C/60% RH"
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:18826818-10c4-972c-618e-01694ff06c89",
          "resource" : {
            "resourceType" : "Specimen",
            "id" : "18826818-10c4-972c-618e-01694ff06c89",
            "text" : // stability18months-3
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Specimen_18826818-10c4-972c-618e-01694ff06c89\"> </a><p><b>Generated Narrative: Specimen</b><a name=\"18826818-10c4-972c-618e-01694ff06c89\"> </a><a name=\"hc18826818-10c4-972c-618e-01694ff06c89\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Specimen &quot;18826818-10c4-972c-618e-01694ff06c89&quot; </p></div><h3>Collections</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Collected[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>2020-12-03</td></tr></table><blockquote><p><b>processing</b></p><p><b>description</b>: Store for 18 months</p><p><b>time</b>: 2020-12 --&gt; 2022-06</p></blockquote><blockquote><p><b>processing</b></p><p><b>description</b>: 25°C/60% RH</p></blockquote></div>"
            },
            "collection" : //  when sample first taken, before the timed periods start
            {
              "collectedDateTime" : "2020-12-03"
            },
            "processing" : [
              {
                "description" : "Store for 18 months",
                "timePeriod" : //  18 months
                {
                  "extension" : [
                    {
                      "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-storage-duration-pq",
                      "valueDuration" : {
                        "value" : 18,
                        "unit" : "month"
                      }
                    }
                  ],
                  "start" : "2020-12",
                  "end" : "2022-06"
                }
              },
              {
                "description" : "25°C/60% RH"
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:e803ad6d-0cb3-87dd-6af1-4b88c654a47c",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "e803ad6d-0cb3-87dd-6af1-4b88c654a47c",
            "text" : // LongTerm25C-18m-1
            {
              "status" : "extensions",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_e803ad6d-0cb3-87dd-6af1-4b88c654a47c\"> </a><p><b>Generated Narrative: Observation</b><a name=\"e803ad6d-0cb3-87dd-6af1-4b88c654a47c\"> </a><a name=\"hce803ad6d-0cb3-87dd-6af1-4b88c654a47c\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;e803ad6d-0cb3-87dd-6af1-4b88c654a47c&quot; </p></div><p><b>Triggered by</b>: See on this page: ActivityDefinition/ce2df6ab-5087-435c-35cb-a84572e756a2</p><p><b>status</b>: final</p><p><b>code</b>: Test Components - Long-term 25C etc - 18 months (XY) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>subject</b>: See on this page: Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</p><p><b>specimen</b>: See on this page: Specimen/18826818-10c4-972c-618e-01694ff06c78</p><p><b>hasMember</b>: </p><ul><li><a name=\"hcLongTerm25C-18m-1-Description\"> </a></li><li><a name=\"hcLongTerm25C-18m-1-Degradation-imp1\"> </a></li><li><a name=\"hcLongTerm25C-18m-1-Degradation-imp2\"> </a></li><li><a name=\"hcLongTerm25C-18m-1-Degradation-imp3\"> </a></li><li><a name=\"hcLongTerm25C-18m-1-Degradation-impUnspecified\"> </a></li><li><a name=\"hcLongTerm25C-18m-1-Degradation-impTotal\"> </a></li><li><a name=\"hcLongTerm25C-18m-1-Water\"> </a></li><li><a name=\"hcLongTerm25C-18m-1-Microbiological\"> </a></li><li><a name=\"hcLongTerm25C-18m-1-Uniformity\"> </a></li></ul><blockquote><p/><p><a name=\"LongTerm25C-18m-1-Description\"> </a></p><p><a name=\"hcLongTerm25C-18m-1-Description\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/1178fc31-0cfd-8c60-0b5b-9ae2850c6774</p><p><b>status</b>: final</p><p><b>code</b>: Description <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DESC)</span></p><p><b>subject</b>: See on this page: Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><blockquote><p/><p><a name=\"LongTerm25C-18m-1-Degradation-imp1\"> </a></p><p><a name=\"hcLongTerm25C-18m-1-Degradation-imp1\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</p><p><b>value</b>: 0.118 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 1 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p/><p><a name=\"LongTerm25C-18m-1-Degradation-imp2\"> </a></p><p><a name=\"hcLongTerm25C-18m-1-Degradation-imp2\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</p><p><b>value</b>: 0.218 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 2 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p/><p><a name=\"LongTerm25C-18m-1-Degradation-imp3\"> </a></p><p><a name=\"hcLongTerm25C-18m-1-Degradation-imp3\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</p><p><b>value</b>: 0.218 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 3 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p/><p><a name=\"LongTerm25C-18m-1-Degradation-impUnspecified\"> </a></p><p><a name=\"hcLongTerm25C-18m-1-Degradation-impUnspecified\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</p><p><b>value</b>: &lt;0.118 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Any Unspecified Degradation Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p/><p><a name=\"LongTerm25C-18m-1-Degradation-impTotal\"> </a></p><p><a name=\"hcLongTerm25C-18m-1-Degradation-impTotal\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</p><p><b>value</b>: 0.818 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Total Degradation Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p/><p><a name=\"LongTerm25C-18m-1-Water\"> </a></p><p><a name=\"hcLongTerm25C-18m-1-Water\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/186eb33e-a01d-4252-166c-b5ba5e8a697c</p><p><b>status</b>: final</p><p><b>code</b>: Water Content <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#WaterContent)</span></p><p><b>subject</b>: See on this page: Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</p><p><b>value</b>: 0.1518 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p></blockquote><blockquote><p/><p><a name=\"LongTerm25C-18m-1-Microbiological\"> </a></p><p><a name=\"hcLongTerm25C-18m-1-Microbiological\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</p><p><b>status</b>: final</p><p><b>code</b>: Microbiological Quality <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Microbiological Quality)</span></p><p><b>subject</b>: See on this page: Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</p><p><b>value</b>: Complies</p></blockquote><blockquote><p/><p><a name=\"LongTerm25C-18m-1-Uniformity\"> </a></p><p><a name=\"hcLongTerm25C-18m-1-Uniformity\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/ef781c18-8e86-7859-209b-469ee9ad42d8</p><p><b>status</b>: final</p><p><b>code</b>: Uniformity of dosage units (by weight) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#uniformity-dosage)</span></p><p><b>subject</b>: See on this page: Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm25C-18m-1-Description</b><a name=\"LongTerm25C-18m-1-Description\"> </a><a name=\"hcLongTerm25C-18m-1-Description\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_1178fc31-0cfd-8c60-0b5b-9ae2850c6774\">ObservationDefinition/1178fc31-0cfd-8c60-0b5b-9ae2850c6774</a></p><p><b>status</b>: final</p><p><b>code</b>: Description <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DESC)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#Medication_7ef62d57-7cc6-9211-66d6-abc7e096093c\">Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-product-impurities-pq-ex1.html#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</a></p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm25C-18m-1-Degradation-imp1</b><a name=\"LongTerm25C-18m-1-Degradation-imp1\"> </a><a name=\"hcLongTerm25C-18m-1-Degradation-imp1\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_2c5683d6-6e94-825b-056a-129a04c95e2f\">ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f</a></p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#Medication_7ef62d57-7cc6-9211-66d6-abc7e096093c\">Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-product-impurities-pq-ex1.html#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</a></p><p><b>value</b>: 0.118 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 1 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm25C-18m-1-Degradation-imp2</b><a name=\"LongTerm25C-18m-1-Degradation-imp2\"> </a><a name=\"hcLongTerm25C-18m-1-Degradation-imp2\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_2c5683d6-6e94-825b-056a-129a04c95e2f\">ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f</a></p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#Medication_7ef62d57-7cc6-9211-66d6-abc7e096093c\">Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-product-impurities-pq-ex1.html#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</a></p><p><b>value</b>: 0.218 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 2 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm25C-18m-1-Degradation-imp3</b><a name=\"LongTerm25C-18m-1-Degradation-imp3\"> </a><a name=\"hcLongTerm25C-18m-1-Degradation-imp3\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_2c5683d6-6e94-825b-056a-129a04c95e2f\">ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f</a></p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#Medication_7ef62d57-7cc6-9211-66d6-abc7e096093c\">Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-product-impurities-pq-ex1.html#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</a></p><p><b>value</b>: 0.218 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 3 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm25C-18m-1-Degradation-impUnspecified</b><a name=\"LongTerm25C-18m-1-Degradation-impUnspecified\"> </a><a name=\"hcLongTerm25C-18m-1-Degradation-impUnspecified\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_2c5683d6-6e94-825b-056a-129a04c95e2f\">ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f</a></p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#Medication_7ef62d57-7cc6-9211-66d6-abc7e096093c\">Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-product-impurities-pq-ex1.html#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</a></p><p><b>value</b>: &lt;0.118 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Any Unspecified Degradation Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm25C-18m-1-Degradation-impTotal</b><a name=\"LongTerm25C-18m-1-Degradation-impTotal\"> </a><a name=\"hcLongTerm25C-18m-1-Degradation-impTotal\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_2c5683d6-6e94-825b-056a-129a04c95e2f\">ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f</a></p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#Medication_7ef62d57-7cc6-9211-66d6-abc7e096093c\">Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-product-impurities-pq-ex1.html#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</a></p><p><b>value</b>: 0.818 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Total Degradation Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm25C-18m-1-Water</b><a name=\"LongTerm25C-18m-1-Water\"> </a><a name=\"hcLongTerm25C-18m-1-Water\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_186eb33e-a01d-4252-166c-b5ba5e8a697c\">ObservationDefinition/186eb33e-a01d-4252-166c-b5ba5e8a697c</a></p><p><b>status</b>: final</p><p><b>code</b>: Water Content <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#WaterContent)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#Medication_7ef62d57-7cc6-9211-66d6-abc7e096093c\">Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-product-impurities-pq-ex1.html#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</a></p><p><b>value</b>: 0.1518 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm25C-18m-1-Microbiological</b><a name=\"LongTerm25C-18m-1-Microbiological\"> </a><a name=\"hcLongTerm25C-18m-1-Microbiological\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_73d9d304-a0b8-31b6-1165-346563b9305e\">ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</a></p><p><b>status</b>: final</p><p><b>code</b>: Microbiological Quality <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Microbiological Quality)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#Medication_7ef62d57-7cc6-9211-66d6-abc7e096093c\">Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-product-impurities-pq-ex1.html#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</a></p><p><b>value</b>: Complies</p></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm25C-18m-1-Uniformity</b><a name=\"LongTerm25C-18m-1-Uniformity\"> </a><a name=\"hcLongTerm25C-18m-1-Uniformity\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_ef781c18-8e86-7859-209b-469ee9ad42d8\">ObservationDefinition/ef781c18-8e86-7859-209b-469ee9ad42d8</a></p><p><b>status</b>: final</p><p><b>code</b>: Uniformity of dosage units (by weight) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#uniformity-dosage)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#Medication_7ef62d57-7cc6-9211-66d6-abc7e096093c\">Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-product-impurities-pq-ex1.html#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</a></p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote></div>"
            },
            "contained" : [
              {
                "resourceType" : "Observation",
                "id" : "LongTerm25C-18m-1-Description",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/1178fc31-0cfd-8c60-0b5b-9ae2850c6774"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Description
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "DESC",
                      "display" : "Description"
                    }
                  ],
                  "text" : "Description"
                },
                "subject" : {
                  "reference" : "Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Medication/medication-batch-information-drug-pq-ex1
                  {
                    "reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
                  }
                ],
                "valueCodeableConcept" : // Organization/tester
                {
                  "text" : "Complies"
                }
              },
              {
                "resourceType" : "Observation",
                "id" : "LongTerm25C-18m-1-Degradation-imp1",
                "meta" : {
                  "profile" : [
                    🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Observation-test-result-drug-pq"
                  ]
                },
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Degradation
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "DGP",
                      "display" : "Degradation Products"
                    }
                  ],
                  "text" : "Degradation Products"
                },
                "subject" : {
                  "reference" : "Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Medication/medication-batch-information-drug-pq-ex1
                  {
                    "reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
                  }
                ],
                "valueQuantity" : // Organization/tester
                {
                  "value" : 0.118,
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                },
                "component" : [
                  {
                    "code" : {
                      "coding" : [
                        {
                          "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                          "code" : "IMP",
                          "display" : "Impurity"
                        }
                      ]
                    },
                    "valueCodeableConcept" : {
                      "text" : "Impurity 1"
                    }
                  }
                ]
              },
              //  could have the code of an impurity substance, or could have an extension to point to it as a resource
              {
                "resourceType" : "Observation",
                "id" : "LongTerm25C-18m-1-Degradation-imp2",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Degradation
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "DGP",
                      "display" : "Degradation Products"
                    }
                  ],
                  "text" : "Degradation Products"
                },
                "subject" : {
                  "reference" : "Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Medication/medication-batch-information-drug-pq-ex1
                  {
                    "reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
                  }
                ],
                "valueQuantity" : // Organization/tester
                {
                  "value" : 0.218,
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                },
                "component" : [
                  {
                    "code" : {
                      "coding" : [
                        {
                          "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                          "code" : "IMP",
                          "display" : "Impurity"
                        }
                      ]
                    },
                    "valueCodeableConcept" : {
                      "text" : "Impurity 2"
                    }
                  }
                ]
              },
              {
                "resourceType" : "Observation",
                "id" : "LongTerm25C-18m-1-Degradation-imp3",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Degradation
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "DGP",
                      "display" : "Degradation Products"
                    }
                  ],
                  "text" : "Degradation Products"
                },
                "subject" : {
                  "reference" : "Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Medication/medication-batch-information-drug-pq-ex1
                  {
                    "reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
                  }
                ],
                "valueQuantity" : // Organization/tester
                {
                  "value" : 0.218,
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                },
                "component" : [
                  {
                    "code" : {
                      "coding" : [
                        {
                          "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                          "code" : "IMP",
                          "display" : "Impurity"
                        }
                      ]
                    },
                    "valueCodeableConcept" : {
                      "text" : "Impurity 3"
                    }
                  }
                ]
              },
              {
                "resourceType" : "Observation",
                "id" : "LongTerm25C-18m-1-Degradation-impUnspecified",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Degradation
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "DGP",
                      "display" : "Degradation Products"
                    }
                  ],
                  "text" : "Degradation Products"
                },
                "subject" : {
                  "reference" : "Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Medication/medication-batch-information-drug-pq-ex1
                  {
                    "reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
                  }
                ],
                "valueQuantity" : // Organization/tester
                {
                  "value" : 0.118,
                  "comparator" : "<",
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                },
                "component" : [
                  {
                    "code" : {
                      "coding" : [
                        {
                          "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                          "code" : "IMP",
                          "display" : "Impurity"
                        }
                      ]
                    },
                    "valueCodeableConcept" : {
                      "text" : "Any Unspecified Degradation Impurity"
                    }
                  }
                ]
              },
              {
                "resourceType" : "Observation",
                "id" : "LongTerm25C-18m-1-Degradation-impTotal",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Degradation
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "DGP",
                      "display" : "Degradation Products"
                    }
                  ],
                  "text" : "Degradation Products"
                },
                "subject" : {
                  "reference" : "Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Medication/medication-batch-information-drug-pq-ex1
                  {
                    "reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
                  }
                ],
                "valueQuantity" : // Organization/tester
                {
                  "value" : 0.818,
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                },
                "component" : [
                  {
                    "code" : {
                      "coding" : [
                        {
                          "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                          "code" : "IMP",
                          "display" : "Impurity"
                        }
                      ]
                    },
                    "valueCodeableConcept" : {
                      "text" : "Total Degradation Impurities"
                    }
                  }
                ]
              },
              {
                "resourceType" : "Observation",
                "id" : "LongTerm25C-18m-1-Water",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/186eb33e-a01d-4252-166c-b5ba5e8a697c"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Water
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "WaterContent",
                      "display" : "Water Content"
                    }
                  ]
                },
                "subject" : {
                  "reference" : "Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Medication/medication-batch-information-drug-pq-ex1
                  {
                    "reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
                  }
                ],
                "valueQuantity" : // Organization/tester
                {
                  "value" : 0.1518,
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                }
              },
              {
                "resourceType" : "Observation",
                "id" : "LongTerm25C-18m-1-Microbiological",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Microbiological
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Microbiological Quality",
                      "display" : "Microbiological Quality"
                    }
                  ]
                },
                "subject" : {
                  "reference" : "Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Medication/medication-batch-information-drug-pq-ex1
                  {
                    "reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
                  }
                ],
                "valueString" : "Complies"
              },
              // Organization/tester
              {
                "resourceType" : "Observation",
                "id" : "LongTerm25C-18m-1-Uniformity",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/ef781c18-8e86-7859-209b-469ee9ad42d8"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Uniformity
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "uniformity-dosage",
                      "display" : "Uniformity of dosage units (by weight)"
                    }
                  ]
                },
                "subject" : {
                  "reference" : "Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Medication/medication-batch-information-drug-pq-ex1
                  {
                    "reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
                  }
                ],
                "valueCodeableConcept" : // Organization/tester
                {
                  "text" : "Complies"
                }
              }
            ],
            "extension" : [
              //  use a standard extension to say what plan this is being done for. However it doesn't link to the step of that plan
                         that would mean using sub-ActivityDefintions probably
              {
                "url" : "http://hl7.org/fhir/StructureDefinition/workflow-triggeredBy",
                "valueReference" : {
                  "reference" : "ActivityDefinition/ce2df6ab-5087-435c-35cb-a84572e756a2"
                }
              }
            ],
            "status" : "final",
            "code" : // ActivityDefinition/activityLongTerm25XY-18
            {
              "text" : "Test Components - Long-term 25C etc - 18 months (XY)"
            },
            "subject" : {
              "reference" : "Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Medication/medication-batch-information-drug-pq-ex1
              {
                "reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
              }
            ],
            "specimen" : // Organization/tester
            {
              "reference" : "Specimen/18826818-10c4-972c-618e-01694ff06c78"
            },
            "hasMember" : [
              // Specimen/stability18months-1
              {
                "reference" : "#LongTerm25C-18m-1-Description"
              },
              {
                "reference" : "#LongTerm25C-18m-1-Degradation-imp1"
              },
              {
                "reference" : "#LongTerm25C-18m-1-Degradation-imp2"
              },
              {
                "reference" : "#LongTerm25C-18m-1-Degradation-imp3"
              },
              {
                "reference" : "#LongTerm25C-18m-1-Degradation-impUnspecified"
              },
              {
                "reference" : "#LongTerm25C-18m-1-Degradation-impTotal"
              },
              {
                "reference" : "#LongTerm25C-18m-1-Water"
              },
              {
                "reference" : "#LongTerm25C-18m-1-Microbiological"
              },
              {
                "reference" : "#LongTerm25C-18m-1-Uniformity"
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:3519f84a-2889-90a0-a6b7-ff2f1be66a73",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "3519f84a-2889-90a0-a6b7-ff2f1be66a73",
            "text" : // LongTerm25C-18m-2
            {
              "status" : "extensions",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_3519f84a-2889-90a0-a6b7-ff2f1be66a73\"> </a><p><b>Generated Narrative: Observation</b><a name=\"3519f84a-2889-90a0-a6b7-ff2f1be66a73\"> </a><a name=\"hc3519f84a-2889-90a0-a6b7-ff2f1be66a73\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;3519f84a-2889-90a0-a6b7-ff2f1be66a73&quot; </p></div><p><b>Triggered by</b>: See on this page: ActivityDefinition/ce2df6ab-5087-435c-35cb-a84572e756a2</p><p><b>status</b>: final</p><p><b>code</b>: Test Components - Long-term 25C etc - 18 months (XY) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>subject</b>: See on this page: Medication/8306cfc5-158f-1a53-a683-048b226060d9</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</p><p><b>specimen</b>: See on this page: Specimen/18826818-10c4-972c-618e-01694ff06c88</p><p><b>hasMember</b>: </p><ul><li><a name=\"hcLongTerm25C-18m-2-Description\"> </a></li><li><a name=\"hcLongTerm25C-18m-2-Microbiological\"> </a></li></ul><blockquote><p/><p><a name=\"LongTerm25C-18m-2-Description\"> </a></p><p><a name=\"hcLongTerm25C-18m-2-Description\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/1178fc31-0cfd-8c60-0b5b-9ae2850c6774</p><p><b>status</b>: final</p><p><b>code</b>: Description <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DESC)</span></p><p><b>subject</b>: See on this page: Medication/8306cfc5-158f-1a53-a683-048b226060d9</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><blockquote><p/><p><a name=\"LongTerm25C-18m-2-Microbiological\"> </a></p><p><a name=\"hcLongTerm25C-18m-2-Microbiological\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</p><p><b>status</b>: final</p><p><b>code</b>: Microbiological Quality <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Microbiological Quality)</span></p><p><b>subject</b>: See on this page: Medication/8306cfc5-158f-1a53-a683-048b226060d9</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</p><p><b>value</b>: Does not comply</p></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm25C-18m-2-Description</b><a name=\"LongTerm25C-18m-2-Description\"> </a><a name=\"hcLongTerm25C-18m-2-Description\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_1178fc31-0cfd-8c60-0b5b-9ae2850c6774\">ObservationDefinition/1178fc31-0cfd-8c60-0b5b-9ae2850c6774</a></p><p><b>status</b>: final</p><p><b>code</b>: Description <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DESC)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#Medication_8306cfc5-158f-1a53-a683-048b226060d9\">Medication/8306cfc5-158f-1a53-a683-048b226060d9</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-product-impurities-pq-ex1.html#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</a></p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm25C-18m-2-Microbiological</b><a name=\"LongTerm25C-18m-2-Microbiological\"> </a><a name=\"hcLongTerm25C-18m-2-Microbiological\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_73d9d304-a0b8-31b6-1165-346563b9305e\">ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</a></p><p><b>status</b>: final</p><p><b>code</b>: Microbiological Quality <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Microbiological Quality)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#Medication_8306cfc5-158f-1a53-a683-048b226060d9\">Medication/8306cfc5-158f-1a53-a683-048b226060d9</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-product-impurities-pq-ex1.html#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</a></p><p><b>value</b>: Does not comply</p></blockquote></div>"
            },
            "contained" : [
              {
                "resourceType" : "Observation",
                "id" : "LongTerm25C-18m-2-Description",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/1178fc31-0cfd-8c60-0b5b-9ae2850c6774"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Description
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "DESC",
                      "display" : "Description"
                    }
                  ],
                  "text" : "Description"
                },
                "subject" : {
                  "reference" : "Medication/8306cfc5-158f-1a53-a683-048b226060d9"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Medication/medication-actual-batch-2
                  {
                    "reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
                  }
                ],
                "valueCodeableConcept" : // Organization/tester
                {
                  "text" : "Complies"
                }
              },
              {
                "resourceType" : "Observation",
                "id" : "LongTerm25C-18m-2-Microbiological",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Microbiological
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Microbiological Quality",
                      "display" : "Microbiological Quality"
                    }
                  ]
                },
                "subject" : {
                  "reference" : "Medication/8306cfc5-158f-1a53-a683-048b226060d9"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Medication/medication-actual-batch-2
                  {
                    "reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
                  }
                ],
                "valueString" : "Does not comply"
              }
            ],
            "extension" : [
              // Organization/tester
              //  use a standard extension to say what plan this is being done for. However it doesn't link to the step of that plan
                         that would mean using sub-ActivityDefintions probably
              {
                "url" : "http://hl7.org/fhir/StructureDefinition/workflow-triggeredBy",
                "valueReference" : {
                  "reference" : "ActivityDefinition/ce2df6ab-5087-435c-35cb-a84572e756a2"
                }
              }
            ],
            "status" : "final",
            "code" : // ActivityDefinition/activityLongTerm25XY-18
            {
              "text" : "Test Components - Long-term 25C etc - 18 months (XY)"
            },
            "subject" : {
              "reference" : "Medication/8306cfc5-158f-1a53-a683-048b226060d9"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Medication/medication-actual-batch-2
              {
                "reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
              }
            ],
            "specimen" : // Organization/tester
            {
              "reference" : "Specimen/18826818-10c4-972c-618e-01694ff06c88"
            },
            "hasMember" : [
              // Specimen/stability18months-2
              {
                "reference" : "#LongTerm25C-18m-2-Description"
              },
              {
                "reference" : "#LongTerm25C-18m-2-Microbiological"
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:2ef362f1-0b65-3578-7f06-fbd74a24694a",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "2ef362f1-0b65-3578-7f06-fbd74a24694a",
            "text" : // LongTerm25C-18m-3
            {
              "status" : "extensions",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_2ef362f1-0b65-3578-7f06-fbd74a24694a\"> </a><p><b>Generated Narrative: Observation</b><a name=\"2ef362f1-0b65-3578-7f06-fbd74a24694a\"> </a><a name=\"hc2ef362f1-0b65-3578-7f06-fbd74a24694a\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;2ef362f1-0b65-3578-7f06-fbd74a24694a&quot; </p></div><p><b>Triggered by</b>: See on this page: ActivityDefinition/ce2df6ab-5087-435c-35cb-a84572e756a2</p><p><b>status</b>: final</p><p><b>code</b>: Test Components - Long-term 25C etc - 18 months (XY) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>subject</b>: See on this page: Medication/f54d4666-7ae3-4e30-8c5a-6d13838c4f3b</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</p><p><b>specimen</b>: See on this page: Specimen/18826818-10c4-972c-618e-01694ff06c89</p><p><b>hasMember</b>: </p><ul><li><a name=\"hcLongTerm25C-18m-3-Description\"> </a></li><li><a name=\"hcLongTerm25C-18m-3-Microbiological\"> </a></li></ul><blockquote><p/><p><a name=\"LongTerm25C-18m-3-Description\"> </a></p><p><a name=\"hcLongTerm25C-18m-3-Description\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/1178fc31-0cfd-8c60-0b5b-9ae2850c6774</p><p><b>status</b>: final</p><p><b>code</b>: Description <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DESC)</span></p><p><b>subject</b>: See on this page: Medication/f54d4666-7ae3-4e30-8c5a-6d13838c4f3b</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><blockquote><p/><p><a name=\"LongTerm25C-18m-3-Microbiological\"> </a></p><p><a name=\"hcLongTerm25C-18m-3-Microbiological\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</p><p><b>status</b>: final</p><p><b>code</b>: Microbiological Quality <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Microbiological Quality)</span></p><p><b>subject</b>: See on this page: Medication/f54d4666-7ae3-4e30-8c5a-6d13838c4f3b</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</p><p><b>value</b>: Does not comply</p></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm25C-18m-3-Description</b><a name=\"LongTerm25C-18m-3-Description\"> </a><a name=\"hcLongTerm25C-18m-3-Description\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_1178fc31-0cfd-8c60-0b5b-9ae2850c6774\">ObservationDefinition/1178fc31-0cfd-8c60-0b5b-9ae2850c6774</a></p><p><b>status</b>: final</p><p><b>code</b>: Description <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DESC)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#Medication_f54d4666-7ae3-4e30-8c5a-6d13838c4f3b\">Medication/f54d4666-7ae3-4e30-8c5a-6d13838c4f3b</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-product-impurities-pq-ex1.html#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</a></p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm25C-18m-3-Microbiological</b><a name=\"LongTerm25C-18m-3-Microbiological\"> </a><a name=\"hcLongTerm25C-18m-3-Microbiological\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_73d9d304-a0b8-31b6-1165-346563b9305e\">ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</a></p><p><b>status</b>: final</p><p><b>code</b>: Microbiological Quality <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Microbiological Quality)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#Medication_f54d4666-7ae3-4e30-8c5a-6d13838c4f3b\">Medication/f54d4666-7ae3-4e30-8c5a-6d13838c4f3b</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-product-impurities-pq-ex1.html#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</a></p><p><b>value</b>: Does not comply</p></blockquote></div>"
            },
            "contained" : [
              {
                "resourceType" : "Observation",
                "id" : "LongTerm25C-18m-3-Description",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/1178fc31-0cfd-8c60-0b5b-9ae2850c6774"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Description
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "DESC",
                      "display" : "Description"
                    }
                  ],
                  "text" : "Description"
                },
                "subject" : {
                  "reference" : "Medication/f54d4666-7ae3-4e30-8c5a-6d13838c4f3b"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Medication/medication-actual-batch-3
                  {
                    "reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
                  }
                ],
                "valueCodeableConcept" : // Organization/tester
                {
                  "text" : "Complies"
                }
              },
              {
                "resourceType" : "Observation",
                "id" : "LongTerm25C-18m-3-Microbiological",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Microbiological
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Microbiological Quality",
                      "display" : "Microbiological Quality"
                    }
                  ]
                },
                "subject" : {
                  "reference" : "Medication/f54d4666-7ae3-4e30-8c5a-6d13838c4f3b"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Medication/medication-actual-batch-3
                  {
                    "reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
                  }
                ],
                "valueString" : "Does not comply"
              }
            ],
            "extension" : [
              // Organization/tester
              //  use a standard extension to say what plan this is being done for. However it doesn't link to the step of that plan
                         that would mean using sub-ActivityDefintions probably
              {
                "url" : "http://hl7.org/fhir/StructureDefinition/workflow-triggeredBy",
                "valueReference" : {
                  "reference" : "ActivityDefinition/ce2df6ab-5087-435c-35cb-a84572e756a2"
                }
              }
            ],
            "status" : "final",
            "code" : // ActivityDefinition/activityLongTerm25XY-18
            {
              "text" : "Test Components - Long-term 25C etc - 18 months (XY)"
            },
            "subject" : {
              "reference" : "Medication/f54d4666-7ae3-4e30-8c5a-6d13838c4f3b"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Medication/medication-actual-batch-3
              {
                "reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
              }
            ],
            "specimen" : // Organization/tester
            {
              "reference" : "Specimen/18826818-10c4-972c-618e-01694ff06c89"
            },
            "hasMember" : [
              // Specimen/stability18months-3
              {
                "reference" : "#LongTerm25C-18m-3-Description"
              },
              {
                "reference" : "#LongTerm25C-18m-3-Microbiological"
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:8a7771db-5cc0-33f8-966a-b2f792bf5785",
          "resource" : {
            "resourceType" : "Specimen",
            "id" : "8a7771db-5cc0-33f8-966a-b2f792bf5785",
            "text" : // stabilityInitialAcc-3
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Specimen_8a7771db-5cc0-33f8-966a-b2f792bf5785\"> </a><p><b>Generated Narrative: Specimen</b><a name=\"8a7771db-5cc0-33f8-966a-b2f792bf5785\"> </a><a name=\"hc8a7771db-5cc0-33f8-966a-b2f792bf5785\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Specimen &quot;8a7771db-5cc0-33f8-966a-b2f792bf5785&quot; </p></div><h3>Collections</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Collected[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>2020-12-01</td></tr></table><blockquote><p><b>processing</b></p><p><b>description</b>: Store for 3 months</p><p><b>time</b>: 2020-12 --&gt; 2021-03</p></blockquote><blockquote><p><b>processing</b></p><p><b>description</b>: 40°C/75% RH</p></blockquote></div>"
            },
            "collection" : //  when sample first taken, before the timed periods start
            {
              "collectedDateTime" : "2020-12-01"
            },
            "processing" : [
              {
                "description" : "Store for 3 months",
                "timePeriod" : //  3 months
                {
                  "extension" : [
                    {
                      "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-storage-duration-pq",
                      "valueDuration" : {
                        "value" : 18,
                        "unit" : "month"
                      }
                    }
                  ],
                  "start" : "2020-12",
                  "end" : "2021-03"
                }
              },
              {
                "description" : "40°C/75% RH"
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:72e0640b-094b-909e-5268-3dee92af4bbd",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "72e0640b-094b-909e-5268-3dee92af4bbd",
            "text" : // Accelerated40C-3-1
            {
              "status" : "extensions",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_72e0640b-094b-909e-5268-3dee92af4bbd\"> </a><p><b>Generated Narrative: Observation</b><a name=\"72e0640b-094b-909e-5268-3dee92af4bbd\"> </a><a name=\"hc72e0640b-094b-909e-5268-3dee92af4bbd\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;72e0640b-094b-909e-5268-3dee92af4bbd&quot; </p></div><p><b>Triggered by</b>: See on this page: ActivityDefinition/096e3f32-798e-6792-76ad-4ea783521c50</p><p><b>status</b>: final</p><p><b>code</b>: Test Components - Accelerated 40C etc - 3 Months (X) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>subject</b>: See on this page: Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</p><p><b>specimen</b>: See on this page: Specimen/8a7771db-5cc0-33f8-966a-b2f792bf5785</p><p><b>hasMember</b>: </p><ul><li><a name=\"hcAccelerated40C-3-1-Description\"> </a></li><li><a name=\"hcAccelerated40C-3-1-Degradation-imp1\"> </a></li><li><a name=\"hcAccelerated40C-3-1-Degradation-imp2\"> </a></li><li><a name=\"hcAccelerated40C-3-1-Degradation-imp3\"> </a></li><li><a name=\"hcAccelerated40C-3-1-Degradation-impUnspecified\"> </a></li><li><a name=\"hcAccelerated40C-3-1-Degradation-impTotal\"> </a></li><li><a name=\"hcAccelerated40C-3-1-Water\"> </a></li><li><a name=\"hcAccelerated40C-3-1-Microbiological\"> </a></li><li><a name=\"hcAccelerated40C-3-1-Uniformity\"> </a></li></ul><blockquote><p/><p><a name=\"Accelerated40C-3-1-Description\"> </a></p><p><a name=\"hcAccelerated40C-3-1-Description\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/1178fc31-0cfd-8c60-0b5b-9ae2850c6774</p><p><b>status</b>: final</p><p><b>code</b>: Description <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DESC)</span></p><p><b>subject</b>: See on this page: Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><blockquote><p/><p><a name=\"Accelerated40C-3-1-Degradation-imp1\"> </a></p><p><a name=\"hcAccelerated40C-3-1-Degradation-imp1\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</p><p><b>value</b>: 0.143 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 1 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p/><p><a name=\"Accelerated40C-3-1-Degradation-imp2\"> </a></p><p><a name=\"hcAccelerated40C-3-1-Degradation-imp2\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</p><p><b>value</b>: 0.243 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 2 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p/><p><a name=\"Accelerated40C-3-1-Degradation-imp3\"> </a></p><p><a name=\"hcAccelerated40C-3-1-Degradation-imp3\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</p><p><b>value</b>: 0.201 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 3 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p/><p><a name=\"Accelerated40C-3-1-Degradation-impUnspecified\"> </a></p><p><a name=\"hcAccelerated40C-3-1-Degradation-impUnspecified\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</p><p><b>value</b>: &lt;0.101 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Any Unspecified Degradation Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p/><p><a name=\"Accelerated40C-3-1-Degradation-impTotal\"> </a></p><p><a name=\"hcAccelerated40C-3-1-Degradation-impTotal\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</p><p><b>value</b>: 0.801 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Total Degradation Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p/><p><a name=\"Accelerated40C-3-1-Water\"> </a></p><p><a name=\"hcAccelerated40C-3-1-Water\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/186eb33e-a01d-4252-166c-b5ba5e8a697c</p><p><b>status</b>: final</p><p><b>code</b>: Water Content <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#WaterContent)</span></p><p><b>subject</b>: See on this page: Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</p><p><b>value</b>: 0.1501 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p></blockquote><blockquote><p/><p><a name=\"Accelerated40C-3-1-Microbiological\"> </a></p><p><a name=\"hcAccelerated40C-3-1-Microbiological\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</p><p><b>status</b>: final</p><p><b>code</b>: Microbiological Quality <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Microbiological Quality)</span></p><p><b>subject</b>: See on this page: Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><blockquote><p/><p><a name=\"Accelerated40C-3-1-Uniformity\"> </a></p><p><a name=\"hcAccelerated40C-3-1-Uniformity\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/ef781c18-8e86-7859-209b-469ee9ad42d8</p><p><b>status</b>: final</p><p><b>code</b>: Uniformity of dosage units (by weight) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#uniformity-dosage)</span></p><p><b>subject</b>: See on this page: Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #Accelerated40C-3-1-Description</b><a name=\"Accelerated40C-3-1-Description\"> </a><a name=\"hcAccelerated40C-3-1-Description\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_1178fc31-0cfd-8c60-0b5b-9ae2850c6774\">ObservationDefinition/1178fc31-0cfd-8c60-0b5b-9ae2850c6774</a></p><p><b>status</b>: final</p><p><b>code</b>: Description <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DESC)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#Medication_7ef62d57-7cc6-9211-66d6-abc7e096093c\">Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-product-impurities-pq-ex1.html#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</a></p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #Accelerated40C-3-1-Degradation-imp1</b><a name=\"Accelerated40C-3-1-Degradation-imp1\"> </a><a name=\"hcAccelerated40C-3-1-Degradation-imp1\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_2c5683d6-6e94-825b-056a-129a04c95e2f\">ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f</a></p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#Medication_7ef62d57-7cc6-9211-66d6-abc7e096093c\">Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-product-impurities-pq-ex1.html#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</a></p><p><b>value</b>: 0.143 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 1 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #Accelerated40C-3-1-Degradation-imp2</b><a name=\"Accelerated40C-3-1-Degradation-imp2\"> </a><a name=\"hcAccelerated40C-3-1-Degradation-imp2\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_2c5683d6-6e94-825b-056a-129a04c95e2f\">ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f</a></p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#Medication_7ef62d57-7cc6-9211-66d6-abc7e096093c\">Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-product-impurities-pq-ex1.html#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</a></p><p><b>value</b>: 0.243 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 2 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #Accelerated40C-3-1-Degradation-imp3</b><a name=\"Accelerated40C-3-1-Degradation-imp3\"> </a><a name=\"hcAccelerated40C-3-1-Degradation-imp3\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_2c5683d6-6e94-825b-056a-129a04c95e2f\">ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f</a></p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#Medication_7ef62d57-7cc6-9211-66d6-abc7e096093c\">Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-product-impurities-pq-ex1.html#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</a></p><p><b>value</b>: 0.201 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 3 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #Accelerated40C-3-1-Degradation-impUnspecified</b><a name=\"Accelerated40C-3-1-Degradation-impUnspecified\"> </a><a name=\"hcAccelerated40C-3-1-Degradation-impUnspecified\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_2c5683d6-6e94-825b-056a-129a04c95e2f\">ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f</a></p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#Medication_7ef62d57-7cc6-9211-66d6-abc7e096093c\">Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-product-impurities-pq-ex1.html#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</a></p><p><b>value</b>: &lt;0.101 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Any Unspecified Degradation Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #Accelerated40C-3-1-Degradation-impTotal</b><a name=\"Accelerated40C-3-1-Degradation-impTotal\"> </a><a name=\"hcAccelerated40C-3-1-Degradation-impTotal\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_2c5683d6-6e94-825b-056a-129a04c95e2f\">ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f</a></p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#Medication_7ef62d57-7cc6-9211-66d6-abc7e096093c\">Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-product-impurities-pq-ex1.html#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</a></p><p><b>value</b>: 0.801 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Total Degradation Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #Accelerated40C-3-1-Water</b><a name=\"Accelerated40C-3-1-Water\"> </a><a name=\"hcAccelerated40C-3-1-Water\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_186eb33e-a01d-4252-166c-b5ba5e8a697c\">ObservationDefinition/186eb33e-a01d-4252-166c-b5ba5e8a697c</a></p><p><b>status</b>: final</p><p><b>code</b>: Water Content <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#WaterContent)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#Medication_7ef62d57-7cc6-9211-66d6-abc7e096093c\">Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-product-impurities-pq-ex1.html#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</a></p><p><b>value</b>: 0.1501 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #Accelerated40C-3-1-Microbiological</b><a name=\"Accelerated40C-3-1-Microbiological\"> </a><a name=\"hcAccelerated40C-3-1-Microbiological\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_73d9d304-a0b8-31b6-1165-346563b9305e\">ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</a></p><p><b>status</b>: final</p><p><b>code</b>: Microbiological Quality <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Microbiological Quality)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#Medication_7ef62d57-7cc6-9211-66d6-abc7e096093c\">Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-product-impurities-pq-ex1.html#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</a></p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #Accelerated40C-3-1-Uniformity</b><a name=\"Accelerated40C-3-1-Uniformity\"> </a><a name=\"hcAccelerated40C-3-1-Uniformity\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_ef781c18-8e86-7859-209b-469ee9ad42d8\">ObservationDefinition/ef781c18-8e86-7859-209b-469ee9ad42d8</a></p><p><b>status</b>: final</p><p><b>code</b>: Uniformity of dosage units (by weight) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#uniformity-dosage)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#Medication_7ef62d57-7cc6-9211-66d6-abc7e096093c\">Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-product-impurities-pq-ex1.html#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9</a></p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote></div>"
            },
            "contained" : [
              {
                "resourceType" : "Observation",
                "id" : "Accelerated40C-3-1-Description",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/1178fc31-0cfd-8c60-0b5b-9ae2850c6774"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Description
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "DESC",
                      "display" : "Description"
                    }
                  ],
                  "text" : "Description"
                },
                "subject" : {
                  "reference" : "Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Medication/medication-batch-information-drug-pq-ex1
                  {
                    "reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
                  }
                ],
                "valueCodeableConcept" : // Organization/tester
                {
                  "text" : "Complies"
                }
              },
              {
                "resourceType" : "Observation",
                "id" : "Accelerated40C-3-1-Degradation-imp1",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Degradation
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "DGP",
                      "display" : "Degradation Products"
                    }
                  ],
                  "text" : "Degradation Products"
                },
                "subject" : {
                  "reference" : "Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Medication/medication-batch-information-drug-pq-ex1
                  {
                    "reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
                  }
                ],
                "valueQuantity" : // Organization/tester
                {
                  "value" : 0.143,
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                },
                "component" : [
                  {
                    "code" : {
                      "coding" : [
                        {
                          "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                          "code" : "IMP",
                          "display" : "Impurity"
                        }
                      ]
                    },
                    "valueCodeableConcept" : {
                      "text" : "Impurity 1"
                    }
                  }
                ]
              },
              //  could have the code of an impurity substance, or could have an extension to point to it as a resource
              {
                "resourceType" : "Observation",
                "id" : "Accelerated40C-3-1-Degradation-imp2",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Degradation
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "DGP",
                      "display" : "Degradation Products"
                    }
                  ],
                  "text" : "Degradation Products"
                },
                "subject" : {
                  "reference" : "Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Medication/medication-batch-information-drug-pq-ex1
                  {
                    "reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
                  }
                ],
                "valueQuantity" : // Organization/tester
                {
                  "value" : 0.243,
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                },
                "component" : [
                  {
                    "code" : {
                      "coding" : [
                        {
                          "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                          "code" : "IMP",
                          "display" : "Impurity"
                        }
                      ]
                    },
                    "valueCodeableConcept" : {
                      "text" : "Impurity 2"
                    }
                  }
                ]
              },
              //  could have the code of an impurity substance, or could have an extension to point to it as a resource
              {
                "resourceType" : "Observation",
                "id" : "Accelerated40C-3-1-Degradation-imp3",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Degradation
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "DGP",
                      "display" : "Degradation Products"
                    }
                  ],
                  "text" : "Degradation Products"
                },
                "subject" : {
                  "reference" : "Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Medication/medication-batch-information-drug-pq-ex1
                  {
                    "reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
                  }
                ],
                "valueQuantity" : // Organization/tester
                {
                  "value" : 0.201,
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                },
                "component" : [
                  {
                    "code" : {
                      "coding" : [
                        {
                          "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                          "code" : "IMP",
                          "display" : "Impurity"
                        }
                      ]
                    },
                    "valueCodeableConcept" : {
                      "text" : "Impurity 3"
                    }
                  }
                ]
              },
              {
                "resourceType" : "Observation",
                "id" : "Accelerated40C-3-1-Degradation-impUnspecified",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Degradation
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "DGP",
                      "display" : "Degradation Products"
                    }
                  ],
                  "text" : "Degradation Products"
                },
                "subject" : {
                  "reference" : "Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Medication/medication-batch-information-drug-pq-ex1
                  {
                    "reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
                  }
                ],
                "valueQuantity" : // Organization/tester
                {
                  "value" : 0.101,
                  "comparator" : "<",
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                },
                "component" : [
                  {
                    "code" : {
                      "coding" : [
                        {
                          "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                          "code" : "IMP",
                          "display" : "Impurity"
                        }
                      ]
                    },
                    "valueCodeableConcept" : {
                      "text" : "Any Unspecified Degradation Impurity"
                    }
                  }
                ]
              },
              {
                "resourceType" : "Observation",
                "id" : "Accelerated40C-3-1-Degradation-impTotal",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/2c5683d6-6e94-825b-056a-129a04c95e2f"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Degradation
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "DGP",
                      "display" : "Degradation Products"
                    }
                  ],
                  "text" : "Degradation Products"
                },
                "subject" : {
                  "reference" : "Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Medication/medication-batch-information-drug-pq-ex1
                  {
                    "reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
                  }
                ],
                "valueQuantity" : // Organization/tester
                {
                  "value" : 0.801,
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                },
                "component" : [
                  {
                    "code" : {
                      "coding" : [
                        {
                          "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                          "code" : "IMP",
                          "display" : "Impurity"
                        }
                      ]
                    },
                    "valueCodeableConcept" : {
                      "text" : "Total Degradation Impurities"
                    }
                  }
                ]
              },
              {
                "resourceType" : "Observation",
                "id" : "Accelerated40C-3-1-Water",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/186eb33e-a01d-4252-166c-b5ba5e8a697c"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Water
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "WaterContent",
                      "display" : "Water Content"
                    }
                  ]
                },
                "subject" : {
                  "reference" : "Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Medication/medication-batch-information-drug-pq-ex1
                  {
                    "reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
                  }
                ],
                "valueQuantity" : // Organization/tester
                {
                  "value" : 0.1501,
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                }
              },
              {
                "resourceType" : "Observation",
                "id" : "Accelerated40C-3-1-Microbiological",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Microbiological
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Microbiological Quality",
                      "display" : "Microbiological Quality"
                    }
                  ]
                },
                "subject" : {
                  "reference" : "Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Medication/medication-batch-information-drug-pq-ex1
                  {
                    "reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
                  }
                ],
                "valueCodeableConcept" : // Organization/tester
                {
                  "text" : "Complies"
                }
              },
              {
                "resourceType" : "Observation",
                "id" : "Accelerated40C-3-1-Uniformity",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/ef781c18-8e86-7859-209b-469ee9ad42d8"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Uniformity
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "uniformity-dosage",
                      "display" : "Uniformity of dosage units (by weight)"
                    }
                  ]
                },
                "subject" : {
                  "reference" : "Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Medication/medication-batch-information-drug-pq-ex1
                  {
                    "reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
                  }
                ],
                "valueCodeableConcept" : // Organization/tester
                {
                  "text" : "Complies"
                }
              }
            ],
            "extension" : [
              //  use a standard extension to say what plan this is being done for. However it doesn't link to the step of that plan
                         that would mean using sub-ActivityDefintions probably
              {
                "url" : "http://hl7.org/fhir/StructureDefinition/workflow-triggeredBy",
                "valueReference" : {
                  "reference" : "ActivityDefinition/096e3f32-798e-6792-76ad-4ea783521c50"
                }
              }
            ],
            "status" : "final",
            "code" : // ActivityDefinition/activityAccelerated40X-3
            {
              "text" : "Test Components - Accelerated 40C etc - 3 Months (X)"
            },
            "subject" : {
              "reference" : "Medication/7ef62d57-7cc6-9211-66d6-abc7e096093c"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Medication/medication-batch-information-drug-pq-ex1
              {
                "reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
              }
            ],
            "specimen" : // Organization/tester
            {
              "reference" : "Specimen/8a7771db-5cc0-33f8-966a-b2f792bf5785"
            },
            "hasMember" : [
              // Specimen/stabilityInitialAcc-3
              {
                "reference" : "#Accelerated40C-3-1-Description"
              },
              {
                "reference" : "#Accelerated40C-3-1-Degradation-imp1"
              },
              {
                "reference" : "#Accelerated40C-3-1-Degradation-imp2"
              },
              {
                "reference" : "#Accelerated40C-3-1-Degradation-imp3"
              },
              {
                "reference" : "#Accelerated40C-3-1-Degradation-impUnspecified"
              },
              {
                "reference" : "#Accelerated40C-3-1-Degradation-impTotal"
              },
              {
                "reference" : "#Accelerated40C-3-1-Water"
              },
              {
                "reference" : "#Accelerated40C-3-1-Microbiological"
              },
              {
                "reference" : "#Accelerated40C-3-1-Uniformity"
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:7ef62d57-7cc6-9211-66d6-abc7e096093c",
          "resource" : {
            "resourceType" : "Medication",
            "id" : "7ef62d57-7cc6-9211-66d6-abc7e096093c",
            "meta" : //  <id value="medication-actual-batch"/>
            // medication-batch-information-drug-pq-ex1
            {
              "profile" : [
                🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Medication-batch-information-drug-pq"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Medication_7ef62d57-7cc6-9211-66d6-abc7e096093c\"> </a><p><b>Generated Narrative: Medication</b><a name=\"7ef62d57-7cc6-9211-66d6-abc7e096093c\"> </a><a name=\"hc7ef62d57-7cc6-9211-66d6-abc7e096093c\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Medication &quot;7ef62d57-7cc6-9211-66d6-abc7e096093c&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-Medication-batch-information-drug-pq.html\">Medication - Batch Information Drug PQ</a></p></div><p><b>code</b>:  <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>Batches</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td><td><b>LotNumber</b></td></tr><tr><td style=\"display: none\">*</td><td>, , , , , </td><td>33445</td></tr></table></div>"
            },
            "code" : {
              "extension" : [
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-medication-definition-pq",
                  "valueReference" : {
                    "reference" : "MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"
                  }
                }
              ]
            },
            "batch" : //  todo consider change this be the MID?
            // MedicinalProductDefinition/medicinalproductdefinition-drug-product-pq-ex1
            {
              "extension" : [
                {
                  "url" : "http://hl7.org/fhir/StructureDefinition/medication-manufacturingBatch",
                  "extension" : [
                    {
                      "url" : "manufacturingDate",
                      "valueDateTime" : "2020-06"
                    },
                    {
                      "url" : "batchQuantity",
                      "valueQuantity" : {
                        "value" : 100100,
                        "unit" : "tablets"
                      }
                    },
                    {
                      "url" : "batchUtilization",
                      "valueCodeableConcept" : {
                        "coding" : [
                          //  could also be C185328 Stability Study?
                          {
                            "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                            "code" : "C133990",
                            "display" : "Commercial"
                          }
                        ],
                        "text" : "Production"
                      }
                    },
                    {
                      "url" : "assignedManufacturer",
                      "valueReference" : {
                        "reference" : "Organization/49d2f0c0-4b28-9271-8aaf-2996a8b9739c"
                      }
                    },
                    // Organization/organization-drug-pq-ex1
                    {
                      "url" : "container",
                      "extension" : [
                        {
                          "url" : "type",
                          "valueCodeableConcept" : {
                            "text" : "100 cc HDPE Bottle 2 g desiccant"
                          }
                        },
                        {
                          "url" : "closureSystemDescription",
                          "valueString" : "Standard closure"
                        }
                      ]
                    }
                  ]
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-release-date-pq",
                  "valueDateTime" : "2019-09-08"
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-substance-batch-pq",
                  "valueReference" : {
                    "reference" : "Substance/fc078762-81c5-5656-9744-13c7ad1e595b"
                  }
                },
                // Substance/substance-dxpq-ex1
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-packaging-date-pq",
                  "valueDateTime" : "2020-08"
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-packaging-site-pq",
                  "valueReference" : {
                    "reference" : "Organization/2dd49242-4bf1-9ec1-5f1e-22ba8d4d5ccc"
                  }
                },
                // Organization/packaging
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-pq",
                  "valueQuantity" : {
                    "value" : 4.8,
                    "unit" : "kg"
                  }
                }
              ],
              "lotNumber" : "33445"
            }
          }
        },
        //  local extensions
        {
          "fullUrl" : "urn:uuid:8306cfc5-158f-1a53-a683-048b226060d9",
          "resource" : {
            "resourceType" : "Medication",
            "id" : "8306cfc5-158f-1a53-a683-048b226060d9",
            "text" : // medication-actual-batch-2
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Medication_8306cfc5-158f-1a53-a683-048b226060d9\"> </a><p><b>Generated Narrative: Medication</b><a name=\"8306cfc5-158f-1a53-a683-048b226060d9\"> </a><a name=\"hc8306cfc5-158f-1a53-a683-048b226060d9\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Medication &quot;8306cfc5-158f-1a53-a683-048b226060d9&quot; </p></div><p><b>code</b>:  <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>Batches</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td><td><b>LotNumber</b></td></tr><tr><td style=\"display: none\">*</td><td>, , , , , </td><td>33446</td></tr></table></div>"
            },
            "code" : {
              "extension" : [
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-medication-definition-pq",
                  "valueReference" : {
                    "reference" : "MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"
                  }
                }
              ]
            },
            "batch" : // MedicinalProductDefinition/medicinalproductdefinition-drug-product-pq-ex1
            {
              "extension" : [
                {
                  "url" : "http://hl7.org/fhir/StructureDefinition/medication-manufacturingBatch",
                  "extension" : [
                    {
                      "url" : "manufacturingDate",
                      "valueDateTime" : "2020-06"
                    },
                    {
                      "url" : "batchQuantity",
                      "valueQuantity" : {
                        "value" : 100050,
                        "unit" : "tablets"
                      }
                    },
                    {
                      "url" : "batchUtilization",
                      "valueCodeableConcept" : {
                        "coding" : [
                          //  could also be C185328 Stability Study?
                          {
                            "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                            "code" : "C133990",
                            "display" : "Commercial"
                          }
                        ],
                        "text" : "Production"
                      }
                    },
                    {
                      "url" : "assignedManufacturer",
                      "valueReference" : {
                        "reference" : "Organization/033ce81d-5f0d-7a3e-93d3-fc64e122a1fd"
                      }
                    },
                    // Organization/manufacturer
                    {
                      "url" : "container",
                      "extension" : [
                        {
                          "url" : "type",
                          "valueCodeableConcept" : {
                            "text" : "100 cc HDPE Bottle 2 g desiccant"
                          }
                        }
                      ]
                    }
                  ]
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-release-date-pq",
                  "valueDateTime" : "2019-09-08"
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-substance-batch-pq",
                  "valueReference" : {
                    "reference" : "Substance/cb31d747-2338-88d5-342c-8e9c097e4dad"
                  }
                },
                // Substance/actual-batch-substance-2
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-packaging-date-pq",
                  "valueDateTime" : "2020-08"
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-packaging-site-pq",
                  "valueReference" : {
                    "reference" : "Organization/2dd49242-4bf1-9ec1-5f1e-22ba8d4d5ccc"
                  }
                },
                // Organization/packaging
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-pq",
                  "valueQuantity" : {
                    "value" : 4.8,
                    "unit" : "kg"
                  }
                }
              ],
              "lotNumber" : "33446"
            }
          }
        },
        //  local extensions
        {
          "fullUrl" : "urn:uuid:f54d4666-7ae3-4e30-8c5a-6d13838c4f3b",
          "resource" : {
            "resourceType" : "Medication",
            "id" : "f54d4666-7ae3-4e30-8c5a-6d13838c4f3b",
            "text" : // medication-actual-batch-3
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Medication_f54d4666-7ae3-4e30-8c5a-6d13838c4f3b\"> </a><p><b>Generated Narrative: Medication</b><a name=\"f54d4666-7ae3-4e30-8c5a-6d13838c4f3b\"> </a><a name=\"hcf54d4666-7ae3-4e30-8c5a-6d13838c4f3b\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Medication &quot;f54d4666-7ae3-4e30-8c5a-6d13838c4f3b&quot; </p></div><p><b>code</b>:  <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>Batches</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td><td><b>LotNumber</b></td></tr><tr><td style=\"display: none\">*</td><td>, , , , , </td><td>33447</td></tr></table></div>"
            },
            "code" : {
              "extension" : [
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-medication-definition-pq",
                  "valueReference" : {
                    "reference" : "MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"
                  }
                }
              ]
            },
            "batch" : // MedicinalProductDefinition/medicinalproductdefinition-drug-product-pq-ex1
            {
              "extension" : [
                {
                  "url" : "http://hl7.org/fhir/StructureDefinition/medication-manufacturingBatch",
                  "extension" : [
                    {
                      "url" : "manufacturingDate",
                      "valueDateTime" : "2020-06"
                    },
                    {
                      "url" : "batchQuantity",
                      "valueQuantity" : {
                        "value" : 100125,
                        "unit" : "tablets"
                      }
                    },
                    {
                      "url" : "batchUtilization",
                      "valueCodeableConcept" : {
                        "coding" : [
                          //  could also be C185328 Stability Study?
                          {
                            "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                            "code" : "C133990",
                            "display" : "Commercial"
                          }
                        ],
                        "text" : "Production"
                      }
                    },
                    {
                      "url" : "assignedManufacturer",
                      "valueReference" : {
                        "reference" : "Organization/033ce81d-5f0d-7a3e-93d3-fc64e122a1fd"
                      }
                    },
                    // Organization/manufacturer
                    {
                      "url" : "container",
                      "extension" : [
                        {
                          "url" : "type",
                          "valueCodeableConcept" : {
                            "text" : "100 cc HDPE Bottle 2 g desiccant"
                          }
                        }
                      ]
                    }
                  ]
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-release-date-pq",
                  "valueDateTime" : "2019-09-08"
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-substance-batch-pq",
                  "valueReference" : {
                    "reference" : "Substance/1551f97b-6f6d-825e-1fb3-44b0b090808c"
                  }
                },
                // Substance/actual-batch-substance-3
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-packaging-date-pq",
                  "valueDateTime" : "2020-08"
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-packaging-site-pq",
                  "valueReference" : {
                    "reference" : "Organization/2dd49242-4bf1-9ec1-5f1e-22ba8d4d5ccc"
                  }
                },
                // Organization/packaging
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-pq",
                  "valueQuantity" : {
                    "value" : 4.8,
                    "unit" : "kg"
                  }
                }
              ],
              "lotNumber" : "33447"
            }
          }
        },
        //  local extensions
        {
          "fullUrl" : "urn:uuid:033ce81d-5f0d-7a3e-93d3-fc64e122a1fd",
          "resource" : {
            "resourceType" : "Organization",
            "id" : "033ce81d-5f0d-7a3e-93d3-fc64e122a1fd",
            "text" : // manufacturer
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Organization_033ce81d-5f0d-7a3e-93d3-fc64e122a1fd\"> </a><p><b>Generated Narrative: Organization</b><a name=\"033ce81d-5f0d-7a3e-93d3-fc64e122a1fd\"> </a><a name=\"hc033ce81d-5f0d-7a3e-93d3-fc64e122a1fd\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Organization &quot;033ce81d-5f0d-7a3e-93d3-fc64e122a1fd&quot; </p></div><p><b>identifier</b>: <code>urn:oid:2.16.840.1.113883.4.82</code>/3010027650</p><p><b>active</b>: true</p><p><b>type</b>: Drug Product Manufacture <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-organization-type.html\">Pharmaceutical Organization Type Codes</a>#drug-product-manufacture)</span></p><p><b>name</b>: AAA Pharmaceutical, Inc.</p><h3>Contacts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Address</b></td></tr><tr><td style=\"display: none\">*</td><td>681 Main Street Lumberton New Jersey 08048 USA </td></tr></table></div>"
            },
            "identifier" : [
              {
                "system" : "urn:oid:2.16.840.1.113883.4.82",
                "value" : "3010027650"
              }
            ],
            "active" : true,
            "type" : [
              //  FDA establishment identifier
              {
                "coding" : [
                  {
                    "system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-organization-type",
                    "code" : "drug-product-manufacture",
                    "display" : "Drug Product Manufacture"
                  }
                ]
              }
            ],
            "name" : "AAA Pharmaceutical, Inc.",
            "contact" : [
              // contact>
                        <address></address>
                    </contact
              {
                "address" : {
                  "line" : [
                    "681 Main Street"
                  ],
                  "city" : "Lumberton",
                  "state" : "New Jersey",
                  "postalCode" : "08048",
                  "country" : "USA"
                }
              }
            ]
          }
        },
        //  todo change to be contact/address
        {
          "fullUrl" : "urn:uuid:2dd49242-4bf1-9ec1-5f1e-22ba8d4d5ccc",
          "resource" : {
            "resourceType" : "Organization",
            "id" : "2dd49242-4bf1-9ec1-5f1e-22ba8d4d5ccc",
            "text" : // packaging
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Organization_2dd49242-4bf1-9ec1-5f1e-22ba8d4d5ccc\"> </a><p><b>Generated Narrative: Organization</b><a name=\"2dd49242-4bf1-9ec1-5f1e-22ba8d4d5ccc\"> </a><a name=\"hc2dd49242-4bf1-9ec1-5f1e-22ba8d4d5ccc\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Organization &quot;2dd49242-4bf1-9ec1-5f1e-22ba8d4d5ccc&quot; </p></div><p><b>identifier</b>: <code>urn:oid:2.16.840.1.113883.4.82</code>/3008816891</p><p><b>active</b>: true</p><p><b>type</b>: Packaging <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-organization-type.html\">Pharmaceutical Organization Type Codes</a>#packaging)</span></p><p><b>name</b>: MySite</p></div>"
            },
            "identifier" : [
              {
                "system" : "urn:oid:2.16.840.1.113883.4.82",
                "value" : "3008816891"
              }
            ],
            "active" : true,
            "type" : [
              {
                "coding" : [
                  {
                    "system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-organization-type",
                    "code" : "packaging",
                    "display" : "Packaging"
                  }
                ]
              }
            ],
            "name" : "MySite"
          }
        },
        {
          "fullUrl" : "urn:uuid:e3d2bc19-2f10-2b4d-1741-e4135fe612a9",
          "resource" : {
            "resourceType" : "Organization",
            "id" : "e3d2bc19-2f10-2b4d-1741-e4135fe612a9",
            "text" : // tester
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\"> </a><p><b>Generated Narrative: Organization</b><a name=\"e3d2bc19-2f10-2b4d-1741-e4135fe612a9\"> </a><a name=\"hce3d2bc19-2f10-2b4d-1741-e4135fe612a9\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Organization &quot;e3d2bc19-2f10-2b4d-1741-e4135fe612a9&quot; </p></div><p><b>identifier</b>: <code>urn:oid:2.16.840.1.113883.4.82</code>/3007270600</p><p><b>active</b>: true</p><p><b>type</b>: Analytical Testing - Stability <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-organization-type.html\">Pharmaceutical Organization Type Codes</a>#analytical-testing-stability)</span></p><p><b>name</b>: Advanced Analytical Testing Laboratories Inc.</p><h3>Contacts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Address</b></td></tr><tr><td style=\"display: none\">*</td><td>30 Silverline Drive North Brunswick New Jersey 08902 USA </td></tr></table></div>"
            },
            "identifier" : [
              //  could also use assigner here, for #74
              {
                "system" : "urn:oid:2.16.840.1.113883.4.82",
                "value" : "3007270600"
              }
            ],
            "active" : true,
            "type" : [
              {
                "coding" : [
                  {
                    "system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-organization-type",
                    "code" : "analytical-testing-stability",
                    "display" : "Analytical Testing - Stability"
                  }
                ]
              }
            ],
            "name" : "Advanced Analytical Testing Laboratories Inc.",
            "contact" : [
              {
                "address" : {
                  "line" : [
                    "30 Silverline Drive"
                  ],
                  "city" : "North Brunswick",
                  "state" : "New Jersey",
                  "postalCode" : "08902",
                  "country" : "USA"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:a0694a7a-aafa-4cbe-8135-c788a9a4d3d5",
          "resource" : //  Section 1.1 - DP Identification
          {
            "resourceType" : "MedicinalProductDefinition",
            "id" : "a0694a7a-aafa-4cbe-8135-c788a9a4d3d5",
            "meta" : //  <id value="product"/>
            // medicinalproductdefinition-drug-product-pq-ex1
            {
              "profile" : [
                🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/MedicinalProductDefinition-drug-product-pq"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"MedicinalProductDefinition_a0694a7a-aafa-4cbe-8135-c788a9a4d3d5\"> </a><p><b>Generated Narrative: MedicinalProductDefinition</b><a name=\"a0694a7a-aafa-4cbe-8135-c788a9a4d3d5\"> </a><a name=\"hca0694a7a-aafa-4cbe-8135-c788a9a4d3d5\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource MedicinalProductDefinition &quot;a0694a7a-aafa-4cbe-8135-c788a9a4d3d5&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-MedicinalProductDefinition-drug-product-pq.html\">MedicinalProductDefinition - Drug Product PQ</a></p></div><p><b>description</b>: Textual description of the product</p><p><b>combinedPharmaceuticalDoseForm</b>: Gastro-resistant tablet <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (standardterms.edqm.eu#10225000)</span></p><p><b>route</b>: Oral use <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (standardterms.edqm.eu#20053000)</span></p><blockquote><p><b>name</b></p><p><b>productName</b>: Stelbat Tablets, 20mg</p><p><b>type</b>: Proprietary <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-productNameType-pq-example.html\">Product Name Type - example</a>#Proprietary)</span></p><h3>Parts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Part</b></td><td><b>Type</b></td></tr><tr><td style=\"display: none\">*</td><td>20mg</td><td>Strength part <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-medicinal-product-name-part-type.html\">Product Name Part Type</a>#StrengthPart)</span></td></tr></table></blockquote></div>"
            },
            "description" : "Textual description of the product",
            "combinedPharmaceuticalDoseForm" : {
              "coding" : [
                {
                  "system" : "http://standardterms.edqm.eu",
                  "code" : "10225000",
                  "display" : "Gastro-resistant tablet"
                }
              ]
            },
            "route" : [
              {
                "coding" : [
                  {
                    "system" : "http://standardterms.edqm.eu",
                    "code" : "20053000",
                    "display" : "Oral use"
                  }
                ]
              }
            ],
            "name" : [
              {
                "productName" : "Stelbat Tablets, 20mg",
                "type" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-productNameType-pq-example",
                      "code" : "Proprietary",
                      "display" : "Proprietary"
                    }
                  ]
                },
                "part" : [
                  {
                    "part" : "20mg",
                    "type" : {
                      "coding" : [
                        {
                          "system" : "http://hl7.org/fhir/medicinal-product-name-part-type",
                          "code" : "StrengthPart",
                          "display" : "Strength part"
                        }
                      ]
                    }
                  }
                ]
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:a0694a7a-aafa-4cbe-8135-c788a9a4d3d6",
          "resource" : {
            "resourceType" : "Ingredient",
            "id" : "a0694a7a-aafa-4cbe-8135-c788a9a4d3d6",
            "meta" : // id value="productIngredient"/
            // ingredient-drug-pq-ex1
            {
              "profile" : [
                🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Ingredient-drug-pq"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Ingredient_a0694a7a-aafa-4cbe-8135-c788a9a4d3d6\"> </a><p><b>Generated Narrative: Ingredient</b><a name=\"a0694a7a-aafa-4cbe-8135-c788a9a4d3d6\"> </a><a name=\"hca0694a7a-aafa-4cbe-8135-c788a9a4d3d6\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Ingredient &quot;a0694a7a-aafa-4cbe-8135-c788a9a4d3d6&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-Ingredient-drug-pq.html\">Ingredient - Drug Pq</a></p></div><p><b>status</b>: active</p><p><b>for</b>: See on this page: MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5</p><p><b>role</b>: Active <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-ingredient-role.html\">Ingredient Role</a>#100000072072)</span></p><blockquote><p><b>substance</b></p><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td>See on this page: SubstanceDefinition/57a9af63-315d-1585-a261-0e337b289390</td></tr></table></blockquote></div>"
            },
            "status" : "active",
            "for" : [
              {
                "reference" : "MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"
              }
            ],
            "role" : // MedicinalProductDefinition/medicinalproductdefinition-drug-product-pq-ex1
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/ingredient-role",
                  "code" : "100000072072",
                  "display" : "Active"
                }
              ]
            },
            "substance" : {
              "code" : {
                "reference" : {
                  "reference" : "SubstanceDefinition/57a9af63-315d-1585-a261-0e337b289390"
                }
              }
            }
          }
        },
        // SubstanceDefinition/substancedefinition-component-substance-drug-pq-ex1
        {
          "fullUrl" : "urn:uuid:57a9af63-315d-1585-a261-0e337b289390",
          "resource" : {
            "resourceType" : "SubstanceDefinition",
            "id" : "57a9af63-315d-1585-a261-0e337b289390",
            "meta" : // substancedefinition-component-substance-drug-pq-ex1
            {
              "profile" : [
                🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/SubstanceDefinition-component-substance-drug-pq"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"SubstanceDefinition_57a9af63-315d-1585-a261-0e337b289390\"> </a><p><b>Generated Narrative: SubstanceDefinition</b><a name=\"57a9af63-315d-1585-a261-0e337b289390\"> </a><a name=\"hc57a9af63-315d-1585-a261-0e337b289390\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource SubstanceDefinition &quot;57a9af63-315d-1585-a261-0e337b289390&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-SubstanceDefinition-component-substance-drug-pq.html\">SubstanceDefinition - Component Substance Drug PQ</a></p></div><p><b>manufacturer</b>: See on this page: Organization/49d2f0c0-4b28-9271-8aaf-2996a8b9739c</p><h3>Names</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Name</b></td></tr><tr><td style=\"display: none\">*</td><td>Stelbatolol</td></tr></table></div>"
            },
            "manufacturer" : [
              {
                "reference" : "Organization/49d2f0c0-4b28-9271-8aaf-2996a8b9739c"
              }
            ],
            "name" : [
              // Organization/organization-drug-pq-ex1
              {
                "name" : "Stelbatolol"
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:49d2f0c0-4b28-9271-8aaf-2996a8b9739c",
          "resource" : {
            "resourceType" : "Organization",
            "id" : "49d2f0c0-4b28-9271-8aaf-2996a8b9739c",
            "meta" : // id value="substance-manufacturer"/
            // organization-drug-pq-ex1
            {
              "profile" : [
                🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Organization-drug-pq"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Organization_49d2f0c0-4b28-9271-8aaf-2996a8b9739c\"> </a><p><b>Generated Narrative: Organization</b><a name=\"49d2f0c0-4b28-9271-8aaf-2996a8b9739c\"> </a><a name=\"hc49d2f0c0-4b28-9271-8aaf-2996a8b9739c\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Organization &quot;49d2f0c0-4b28-9271-8aaf-2996a8b9739c&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-Organization-drug-pq.html\">Organization - Drug PQ</a></p></div><p><b>identifier</b>: <code>urn:oid:2.16.840.1.113883.4.82</code>/3003040516</p><p><b>active</b>: true</p><p><b>type</b>: Drug Substance Manufacture <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-organization-type.html\">Pharmaceutical Organization Type Codes</a>#drug-substance-manufacture)</span></p><p><b>name</b>: AAA Molybdenum Products, Inc.</p><h3>Contacts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Address</b></td></tr><tr><td style=\"display: none\">*</td><td>7233 W 116th Pl Ste C Broomfield Colorado 80020 USA </td></tr></table></div>"
            },
            "identifier" : [
              {
                "system" : "urn:oid:2.16.840.1.113883.4.82",
                "value" : "3003040516"
              }
            ],
            "active" : true,
            "type" : [
              //  FDA establishment identifier
              {
                "coding" : [
                  {
                    "system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-organization-type",
                    "code" : "drug-substance-manufacture",
                    "display" : "Drug Substance Manufacture"
                  }
                ]
              }
            ],
            "name" : "AAA Molybdenum Products, Inc.",
            "contact" : [
              {
                "address" : {
                  "line" : [
                    "7233 W 116th Pl",
                    "Ste C"
                  ],
                  "city" : "Broomfield",
                  "state" : "Colorado",
                  "postalCode" : "80020",
                  "country" : "USA"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:fc078762-81c5-5656-9744-13c7ad1e595b",
          "resource" : {
            "resourceType" : "Substance",
            "id" : "fc078762-81c5-5656-9744-13c7ad1e595b",
            "meta" : // <id value="actual-batch-substance"/>
            // substance-dxpq-ex1
            {
              "profile" : [
                🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Substance-drug-pq"
              ]
            },
            "text" : {
              "status" : "extensions",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Substance_fc078762-81c5-5656-9744-13c7ad1e595b\"> </a><p><b>Generated Narrative: Substance</b><a name=\"fc078762-81c5-5656-9744-13c7ad1e595b\"> </a><a name=\"hcfc078762-81c5-5656-9744-13c7ad1e595b\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Substance &quot;fc078762-81c5-5656-9744-13c7ad1e595b&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-Substance-drug-pq.html\">Substance - Drug PQ</a></p></div><blockquote><p><b>Medication Manufacturing Batch</b></p><blockquote><p><b>url</b></p><code>manufacturingDate</code></blockquote><p><b>value</b>: 2019-09-07</p><blockquote><p><b>url</b></p><code>batchQuantity</code></blockquote><p><b>value</b>: 5 kg</p><blockquote><p><b>url</b></p><code>batchUtilization</code></blockquote><p><b>value</b>: Development <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.0.0/CodeSystem-v3-nciThesaurus.html\">NCI Thesaurus</a>#C133991)</span></p><blockquote><p><b>url</b></p><code>assignedManufacturer</code></blockquote><p><b>value</b>: See on this page: Organization/49d2f0c0-4b28-9271-8aaf-2996a8b9739c</p></blockquote><p><b>Extension - Batch Release Date PQ</b>: 2019-09-08</p><p><b>Extension - Batch Retest Date PQ</b>: 2022-09-08</p><p><b>Extension - Actual Yield PQ</b>: 4.8 kg</p><p><b>identifier</b>: CAT1</p><p><b>instance</b>: true</p><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td>See on this page: SubstanceDefinition/57a9af63-315d-1585-a261-0e337b289390</td></tr></table></div>"
            },
            "extension" : [
              {
                "url" : "http://hl7.org/fhir/StructureDefinition/medication-manufacturingBatch",
                "extension" : [
                  {
                    "url" : "manufacturingDate",
                    "valueDateTime" : "2019-09-07"
                  },
                  {
                    "url" : "batchQuantity",
                    "valueQuantity" : {
                      "value" : 5,
                      "unit" : "kg"
                    }
                  },
                  {
                    "url" : "batchUtilization",
                    "valueCodeableConcept" : {
                      "coding" : [
                        {
                          "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                          "code" : "C133991",
                          "display" : "Development"
                        }
                      ]
                    }
                  },
                  {
                    "url" : "assignedManufacturer",
                    "valueReference" : {
                      "reference" : "Organization/49d2f0c0-4b28-9271-8aaf-2996a8b9739c"
                    }
                  }
                ]
              },
              // Organization/organization-drug-pq-ex1
              {
                "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-release-date-pq",
                "valueDateTime" : "2019-09-08"
              },
              {
                "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-retest-date-pq",
                "valueDateTime" : "2022-09-08"
              },
              {
                "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-pq",
                "valueQuantity" : {
                  "value" : 4.8,
                  "unit" : "kg"
                }
              }
            ],
            "identifier" : [
              //  local extensions
              {
                "value" : "CAT1"
              }
            ],
            "instance" : true,
            "code" : {
              "reference" : {
                "reference" : "SubstanceDefinition/57a9af63-315d-1585-a261-0e337b289390"
              }
            }
          }
        },
        // SubstanceDefinition/substancedefinition-component-substance-drug-pq-ex1
        {
          "fullUrl" : "urn:uuid:cb31d747-2338-88d5-342c-8e9c097e4dad",
          "resource" : {
            "resourceType" : "Substance",
            "id" : "cb31d747-2338-88d5-342c-8e9c097e4dad",
            "text" : // actual-batch-substance-2
            {
              "status" : "extensions",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Substance_cb31d747-2338-88d5-342c-8e9c097e4dad\"> </a><p><b>Generated Narrative: Substance</b><a name=\"cb31d747-2338-88d5-342c-8e9c097e4dad\"> </a><a name=\"hccb31d747-2338-88d5-342c-8e9c097e4dad\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Substance &quot;cb31d747-2338-88d5-342c-8e9c097e4dad&quot; </p></div><blockquote><p><b>Medication Manufacturing Batch</b></p><blockquote><p><b>url</b></p><code>manufacturingDate</code></blockquote><p><b>value</b>: 2019-09-07</p><blockquote><p><b>url</b></p><code>batchQuantity</code></blockquote><p><b>value</b>: 5 kg</p><blockquote><p><b>url</b></p><code>batchUtilization</code></blockquote><p><b>value</b>: Development <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.0.0/CodeSystem-v3-nciThesaurus.html\">NCI Thesaurus</a>#C133991)</span></p><blockquote><p><b>url</b></p><code>assignedManufacturer</code></blockquote><p><b>value</b>: See on this page: Organization/49d2f0c0-4b28-9271-8aaf-2996a8b9739c</p></blockquote><p><b>Extension - Batch Release Date PQ</b>: 2019-09-08</p><p><b>Extension - Batch Retest Date PQ</b>: 2022-09-08</p><p><b>Extension - Actual Yield PQ</b>: 4.8 kg</p><p><b>identifier</b>: CAT2</p><p><b>instance</b>: true</p><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td>See on this page: SubstanceDefinition/57a9af63-315d-1585-a261-0e337b289390</td></tr></table></div>"
            },
            "extension" : [
              {
                "url" : "http://hl7.org/fhir/StructureDefinition/medication-manufacturingBatch",
                "extension" : [
                  {
                    "url" : "manufacturingDate",
                    "valueDateTime" : "2019-09-07"
                  },
                  {
                    "url" : "batchQuantity",
                    "valueQuantity" : {
                      "value" : 5,
                      "unit" : "kg"
                    }
                  },
                  {
                    "url" : "batchUtilization",
                    "valueCodeableConcept" : {
                      "coding" : [
                        {
                          "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                          "code" : "C133991",
                          "display" : "Development"
                        }
                      ]
                    }
                  },
                  {
                    "url" : "assignedManufacturer",
                    "valueReference" : {
                      "reference" : "Organization/49d2f0c0-4b28-9271-8aaf-2996a8b9739c"
                    }
                  }
                ]
              },
              // Organization/organization-drug-pq-ex1
              {
                "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-release-date-pq",
                "valueDateTime" : "2019-09-08"
              },
              {
                "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-retest-date-pq",
                "valueDateTime" : "2022-09-08"
              },
              {
                "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-pq",
                "valueQuantity" : {
                  "value" : 4.8,
                  "unit" : "kg"
                }
              }
            ],
            "identifier" : [
              //  local extensions
              {
                "value" : "CAT2"
              }
            ],
            "instance" : true,
            "code" : {
              "reference" : {
                "reference" : "SubstanceDefinition/57a9af63-315d-1585-a261-0e337b289390"
              }
            }
          }
        },
        // SubstanceDefinition/substancedefinition-component-substance-drug-pq-ex1
        {
          "fullUrl" : "urn:uuid:1551f97b-6f6d-825e-1fb3-44b0b090808c",
          "resource" : {
            "resourceType" : "Substance",
            "id" : "1551f97b-6f6d-825e-1fb3-44b0b090808c",
            "text" : // actual-batch-substance-3
            {
              "status" : "extensions",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Substance_1551f97b-6f6d-825e-1fb3-44b0b090808c\"> </a><p><b>Generated Narrative: Substance</b><a name=\"1551f97b-6f6d-825e-1fb3-44b0b090808c\"> </a><a name=\"hc1551f97b-6f6d-825e-1fb3-44b0b090808c\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Substance &quot;1551f97b-6f6d-825e-1fb3-44b0b090808c&quot; </p></div><blockquote><p><b>Medication Manufacturing Batch</b></p><blockquote><p><b>url</b></p><code>manufacturingDate</code></blockquote><p><b>value</b>: 2019-09-07</p><blockquote><p><b>url</b></p><code>batchQuantity</code></blockquote><p><b>value</b>: 5 kg</p><blockquote><p><b>url</b></p><code>batchUtilization</code></blockquote><p><b>value</b>: Development <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.0.0/CodeSystem-v3-nciThesaurus.html\">NCI Thesaurus</a>#C133991)</span></p><blockquote><p><b>url</b></p><code>assignedManufacturer</code></blockquote><p><b>value</b>: See on this page: Organization/49d2f0c0-4b28-9271-8aaf-2996a8b9739c</p></blockquote><p><b>Extension - Batch Release Date PQ</b>: 2019-09-08</p><p><b>Extension - Batch Retest Date PQ</b>: 2022-09-08</p><p><b>Extension - Actual Yield PQ</b>: 4.8 kg</p><p><b>identifier</b>: CAT3</p><p><b>instance</b>: true</p><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td>See on this page: SubstanceDefinition/57a9af63-315d-1585-a261-0e337b289390</td></tr></table></div>"
            },
            "extension" : [
              {
                "url" : "http://hl7.org/fhir/StructureDefinition/medication-manufacturingBatch",
                "extension" : [
                  {
                    "url" : "manufacturingDate",
                    "valueDateTime" : "2019-09-07"
                  },
                  {
                    "url" : "batchQuantity",
                    "valueQuantity" : {
                      "value" : 5,
                      "unit" : "kg"
                    }
                  },
                  {
                    "url" : "batchUtilization",
                    "valueCodeableConcept" : {
                      "coding" : [
                        {
                          "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                          "code" : "C133991",
                          "display" : "Development"
                        }
                      ]
                    }
                  },
                  {
                    "url" : "assignedManufacturer",
                    "valueReference" : {
                      "reference" : "Organization/49d2f0c0-4b28-9271-8aaf-2996a8b9739c"
                    }
                  }
                ]
              },
              // Organization/organization-drug-pq-ex1
              {
                "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-release-date-pq",
                "valueDateTime" : "2019-09-08"
              },
              {
                "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-retest-date-pq",
                "valueDateTime" : "2022-09-08"
              },
              {
                "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-pq",
                "valueQuantity" : {
                  "value" : 4.8,
                  "unit" : "kg"
                }
              }
            ],
            "identifier" : [
              //  local extensions
              {
                "value" : "CAT3"
              }
            ],
            "instance" : true,
            "code" : {
              "reference" : {
                "reference" : "SubstanceDefinition/57a9af63-315d-1585-a261-0e337b289390"
              }
            }
          }
        }
      ]
    }