Pharmaceutical Quality (Industry)
1.0.0 - STU1

Pharmaceutical Quality (Industry), published by HL7 International / Biomedical Research and Regulation. This guide is not an authorized publication; it is the continuous build for version 1.0.0 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/uv-dx-pq/ and changes regularly. See the Directory of published versions

## : Example: Bundle – Stability, substance - JSON Representation

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    //  Substance Stability Study
    {
      "resourceType" : "Bundle",
      "id" : "bundle-drug-stability-pq-ex2-sub",
      "meta" : {
        "profile" : [
          🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Bundle-drug-stability-pq"
        ]
      },
      "type" : "collection",
      "entry" : [
        //  Section 11 - Stability Study - Results
        {
          "fullUrl" : "urn:uuid:54c8e8dc-9a19-0dc2-910e-d5a05d6ba003",
          "resource" : {
            "resourceType" : "DiagnosticReport",
            "id" : "studyResultsReport",
            "text" : {
              "status" : "extensions",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"DiagnosticReport_studyResultsReport\"> </a><p><b>Generated Narrative: DiagnosticReport</b><a name=\"studyResultsReport\"> </a><a name=\"hcstudyResultsReport\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource DiagnosticReport &quot;studyResultsReport&quot; </p></div><p><b>Triggered by</b>: See on this page: PlanDefinition/c3973835-10ca-0796-0a26-aa8afafc9c5b</p><p><b>Extension - Statistical Model PQ</b>: information about statistical model utilized to interpret stability study results <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>Extension - Container Orientation PQ</b>: Horizontal <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-container-orientation.html\">Container Orientation Codes</a>#horizontal &quot;horizontal&quot;)</span></p><p><b>identifier</b>: <code>https://eudract.europa.eu/example/identifier</code>/PLO555</p><p><b>status</b>: final</p><p><b>code</b>: Stability Study Report <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-report-type.html\">Pharmaceutical Report Type Codes</a>#Stability Study Report)</span></p><p><b>effective</b>: 2019-09-08</p><p><b>performer</b>: See on this page: Organization/6049d921-9935-90b7-4efc-894a66483c00</p><p><b>result</b>: </p><ul><li>See on this page: Observation/588a6787-0454-55ef-0b8a-4c8941b6976c</li><li>See on this page: Observation/930c7f69-2546-7148-2069-b3be3a755edf</li><li>See on this page: Observation/8070745c-30c4-a52e-41fd-600a913578d4</li><li>See on this page: Observation/f16113fe-27e7-0aa2-6787-9415f5051900</li><li>See on this page: Observation/1b25eb25-9149-02f6-9676-c87f90c64904</li><li>See on this page: Observation/004ed877-7729-834e-3b6b-a2cf4bdb2377</li><li>See on this page: Observation/f958e1e9-6023-4e39-2ffe-a9c8f135a2dd</li></ul><p><b>conclusion</b>: The samples have been assessed and the conclusion is...</p></div>"
            },
            "extension" : [
              {
                "url" : "http://hl7.org/fhir/StructureDefinition/workflow-triggeredBy",
                "valueReference" : {
                  "reference" : "PlanDefinition/c3973835-10ca-0796-0a26-aa8afafc9c5b"
                }
              },
              // PlanDefinition/stabilityStudyProtocol
              {
                "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-statistical-model-pq",
                "valueCodeableConcept" : {
                  "text" : "information about statistical model utilized to interpret stability study results"
                }
              },
              //  Want to use studyDesign, but problem is that this is CodeableConcept, which allows text. However when you use text, you then
                                have no place to put a context. Ideally this would be a code/code pair.
                                Code says "statistical model", code (or text) then says what it is
              {
                "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-container-orientation-pq",
                "valueCodeableConcept" : {
                  "coding" : [
                    {
                      "system" : "http://terminology.hl7.org/CodeSystem/container-orientation",
                      "code" : "horizontal",
                      "display" : "horizontal"
                    }
                  ],
                  "text" : "Horizontal"
                }
              }
            ],
            "identifier" : [
              {
                "system" : "https://eudract.europa.eu/example/identifier",
                "value" : "PLO555"
              }
            ],
            "status" : "final",
            "code" : {
              "coding" : [
                {
                  "system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-report-type",
                  "code" : "Stability Study Report",
                  "display" : "Stability Study Report"
                }
              ]
            },
            "effectiveDateTime" : "2019-09-08",
            "_effectiveDateTime" : {
              "extension" : [
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-time-point-description-pq",
                  "valueCodeableConcept" : {
                    "coding" : [
                      {
                        "system" : "http://terminology.hl7.org/CodeSystem/time-point-description",
                        "code" : "Delayed Start Code",
                        "display" : "Delayed Start Code"
                      }
                    ],
                    "text" : "Refrigerated delayed testing"
                  }
                }
              ]
            },
            "performer" : [
              {
                "reference" : "Organization/6049d921-9935-90b7-4efc-894a66483c00"
              }
            ],
            "result" : [
              // Organization/tester
              {
                "reference" : "Observation/588a6787-0454-55ef-0b8a-4c8941b6976c"
              },
              // Observation/LongTerm30C-initial-1
              {
                "reference" : "Observation/930c7f69-2546-7148-2069-b3be3a755edf"
              },
              // Observation/LongTerm30C-Initial-2
              {
                "reference" : "Observation/8070745c-30c4-a52e-41fd-600a913578d4"
              },
              // Observation/LongTerm30C-Initial-3
              {
                "reference" : "Observation/f16113fe-27e7-0aa2-6787-9415f5051900"
              },
              // Observation/LongTerm30C-18m
              {
                "reference" : "Observation/1b25eb25-9149-02f6-9676-c87f90c64904"
              },
              // Observation/LongTerm30C-18m-2
              {
                "reference" : "Observation/004ed877-7729-834e-3b6b-a2cf4bdb2377"
              },
              // Observation/LongTerm30C-18m-3
              {
                "reference" : "Observation/f958e1e9-6023-4e39-2ffe-a9c8f135a2dd"
              }
            ],
            "conclusion" : "The samples have been assessed and the conclusion is..."
          }
        },
        // Observation/Accelerated40C-3m
        {
          "fullUrl" : "urn:uuid:c3973835-10ca-0796-0a26-aa8afafc9c5b",
          "resource" : //  Section 11 - Stability Study - Protocol
          {
            "resourceType" : "PlanDefinition",
            "id" : "c3973835-10ca-0796-0a26-aa8afafc9c5b",
            "text" : // stabilityStudyProtocol
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"PlanDefinition_c3973835-10ca-0796-0a26-aa8afafc9c5b\"> </a><p><b>Generated Narrative: PlanDefinition</b><a name=\"c3973835-10ca-0796-0a26-aa8afafc9c5b\"> </a><a name=\"hcc3973835-10ca-0796-0a26-aa8afafc9c5b\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource PlanDefinition &quot;c3973835-10ca-0796-0a26-aa8afafc9c5b&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/PlanDefinition/c3973835-10ca-0796-0a26-aa8afafc9c5b</code></p><p><b>title</b>: Stability Monitoring Program</p><p><b>type</b>: Stability Study Protocol <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-plan-type.html\">Pharmaceutical Plan Type Codes</a>#1244588)</span></p><p><b>status</b>: active</p><p><b>subject</b>: See on this page: SubstanceDefinition/2e3a85b5-790a-a108-3627-edf0ec6f1210</p><p><b>description</b>: Description of the study study plan which includes tests, time points, storage conditions, method</p><blockquote><p><b>action</b></p><p><b>title</b>: Stability Test Protocol for Long-term and Accelerated Storage of Stelbatolol</p><blockquote><p><b>action</b></p><p><b>title</b>: Long-Term</p><p><b>description</b>: 30°C/65% RH</p><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote></blockquote><blockquote><p><b>action</b></p><p><b>title</b>: Accelerated</p><p><b>description</b>: 40°C/75% RH</p><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote></blockquote></blockquote></div>"
            },
            "url" : "http://example-server.com/fhir/PlanDefinition/c3973835-10ca-0796-0a26-aa8afafc9c5b",
            "title" : "Stability Monitoring Program",
            "type" : // http://example-server.com/fhir/PlanDefinition/c3973835-10ca-0796-0a26-aa8afafc9c5b
            //             Added type (8/22/2023)
            {
              "coding" : [
                {
                  "system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-plan-type",
                  "code" : "1244588",
                  "display" : "Stability Study Protocol"
                }
              ]
            },
            "status" : "active",
            "subjectReference" : {
              "reference" : "SubstanceDefinition/2e3a85b5-790a-a108-3627-edf0ec6f1210"
            },
            "description" : "Description of the study study plan which includes tests, time points, storage conditions, method",
            "action" : [
              // SubstanceDefinition/substance1
              //  unclear if want subject here, because it may apply to different ones
              // subjectCanonical value="MedicinalProductDefinition/product"/
              //  this isn't followed at the moment, if it isnt in the file
              //  end of accelerated
              {
                "title" : "Stability Test Protocol for Long-term and Accelerated Storage of Stelbatolol",
                "action" : [
                  {
                    "title" : "Long-Term",
                    "description" : "30°C/65% RH",
                    "action" : [
                      //  TODO add codes here for the different levels?
                      {
                        "title" : "Initial",
                        "timingTiming" : //  0 months
                        {
                          "repeat" : {
                            "boundsRange" : {
                              "low" : {
                                "value" : 0,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              },
                              "high" : {
                                "value" : 0,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              }
                            },
                            "frequency" : 1
                          }
                        },
                        "action" : [
                          {
                            "title" : "XY",
                            "definitionCanonical" : "http://example-server.com/fhir/ActivityDefinition/10d7b693-7a0e-2f71-9a10-642e5a0a5d42"
                          }
                        ]
                      },
                      //  the categories to do at this step
                      //  Long term
                      // ActivityDefinition/activityLongTerm30XY-Initial
                      {
                        "title" : "3",
                        "timingTiming" : //  3 months
                        {
                          "repeat" : {
                            "boundsRange" : {
                              "low" : {
                                "value" : 3,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              },
                              "high" : {
                                "value" : 3,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              }
                            },
                            "frequency" : 1
                          }
                        },
                        "action" : [
                          {
                            "title" : "X",
                            "definitionCanonical" : "http://example-server.com/fhir/ActivityDefinition/480a61f8-14b3-233e-8e5f-7f0db9696a1e"
                          }
                        ]
                      },
                      // ActivityDefinition/activityLongTerm30X-3
                      {
                        "title" : "6",
                        "timingTiming" : //  6 months
                        {
                          "repeat" : {
                            "boundsRange" : {
                              "low" : {
                                "value" : 6,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              },
                              "high" : {
                                "value" : 6,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              }
                            },
                            "frequency" : 1
                          }
                        },
                        "action" : [
                          {
                            "title" : "X",
                            "definitionCanonical" : "http://example-server.com/fhir/ActivityDefinition/bee486c4-6ab5-6293-4114-d4be24f303d3"
                          }
                        ]
                      },
                      // ActivityDefinition/activityLongTerm30X-6
                      {
                        "title" : "9",
                        "timingTiming" : //  9 months
                        {
                          "repeat" : {
                            "boundsRange" : {
                              "low" : {
                                "value" : 9,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              },
                              "high" : {
                                "value" : 9,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              }
                            },
                            "frequency" : 1
                          }
                        },
                        "action" : [
                          {
                            "title" : "X",
                            "definitionCanonical" : "http://example-server.com/fhir/ActivityDefinition/99893d3c-520c-8d7b-6d73-f46b1a662201"
                          }
                        ]
                      },
                      // ActivityDefinition/activityLongTerm30X-9
                      {
                        "title" : "12",
                        "timingTiming" : //  12 months
                        {
                          "repeat" : {
                            "boundsRange" : {
                              "low" : {
                                "value" : 12,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              },
                              "high" : {
                                "value" : 12,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              }
                            },
                            "frequency" : 1
                          }
                        },
                        "action" : [
                          {
                            "title" : "X",
                            "definitionCanonical" : "http://example-server.com/fhir/ActivityDefinition/b3254b8e-6fc3-88d3-7d38-0afcf13c4f67"
                          }
                        ]
                      },
                      // ActivityDefinition/activityLongTerm30X-12
                      {
                        "title" : "18",
                        "timingTiming" : //  18 months
                        {
                          "repeat" : {
                            "boundsRange" : {
                              "low" : {
                                "value" : 18,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              },
                              "high" : {
                                "value" : 18,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              }
                            },
                            "frequency" : 1
                          }
                        },
                        "action" : [
                          {
                            "title" : "X",
                            "definitionCanonical" : "http://example-server.com/fhir/ActivityDefinition/c9b53a46-2f61-7b3f-5780-5f5c79a47f12"
                          }
                        ]
                      },
                      // ActivityDefinition/activityLongTerm30X-18
                      {
                        "title" : "24",
                        "timingTiming" : //  24 months
                        {
                          "repeat" : {
                            "boundsRange" : {
                              "low" : {
                                "value" : 24,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              },
                              "high" : {
                                "value" : 24,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              }
                            },
                            "frequency" : 1
                          }
                        },
                        "action" : [
                          {
                            "title" : "X",
                            "definitionCanonical" : "http://example-server.com/fhir/ActivityDefinition/d6f7de9d-57a5-6a2c-1c2f-0d65718860f2"
                          }
                        ]
                      },
                      // ActivityDefinition/activityLongTerm30X-24
                      {
                        "title" : "36",
                        "timingTiming" : {
                          "repeat" : {
                            "boundsRange" : {
                              "low" : {
                                "value" : 36,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              },
                              "high" : {
                                "value" : 36,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              }
                            },
                            "frequency" : 1
                          }
                        },
                        "action" : [
                          {
                            "title" : "(X)",
                            "requiredBehavior" : "could",
                            "definitionCanonical" : "http://example-server.com/fhir/ActivityDefinition/75073965-82eb-407d-34cf-3a7767a38149"
                          }
                        ]
                      }
                    ]
                  },
                  // ActivityDefinition/activityLongTerm30X-36
                  //  36 months
                  {
                    "title" : "Accelerated",
                    "description" : "40°C/75% RH",
                    "action" : [
                      {
                        "title" : "Initial",
                        "timingTiming" : //  0 months
                        {
                          "repeat" : {
                            "boundsRange" : {
                              "low" : {
                                "value" : 0,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              },
                              "high" : {
                                "value" : 0,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              }
                            },
                            "frequency" : 1
                          }
                        },
                        "action" : [
                          {
                            "title" : "XY",
                            "definitionCanonical" : "http://example-server.com/fhir/ActivityDefinition/1b43a536-3c29-3427-0b93-e35866ef8495"
                          }
                        ]
                      },
                      //  second category at this step
                      // ActivityDefinition/activityAccelerated40XY-Initial
                      {
                        "title" : "3",
                        "timingTiming" : //  3 months
                        {
                          "repeat" : {
                            "boundsRange" : {
                              "low" : {
                                "value" : 3,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              },
                              "high" : {
                                "value" : 3,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              }
                            },
                            "frequency" : 1
                          }
                        },
                        "action" : [
                          {
                            "title" : "X",
                            "definitionCanonical" : "http://example-server.com/fhir/ActivityDefinition/8a453cd8-1ac3-4c86-48c3-3e5ea9ee76a9"
                          }
                        ]
                      },
                      // ActivityDefinition/activityAccelerated40X-3
                      {
                        "title" : "6",
                        "timingTiming" : //  6 months
                        {
                          "repeat" : {
                            "boundsRange" : {
                              "low" : {
                                "value" : 6,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              },
                              "high" : {
                                "value" : 6,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              }
                            },
                            "frequency" : 1
                          }
                        },
                        "action" : [
                          {
                            "title" : "X",
                            "definitionCanonical" : "http://example-server.com/fhir/ActivityDefinition/cf2f00df-971f-0bab-8768-4251b1ad0817"
                          }
                        ]
                      },
                      // ActivityDefinition/activityAccelerated40X-6
                      {
                        "title" : "9",
                        "timingTiming" : //  9 months
                        {
                          "repeat" : {
                            "boundsRange" : {
                              "low" : {
                                "value" : 9,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              },
                              "high" : {
                                "value" : 9,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              }
                            },
                            "frequency" : 1
                          }
                        },
                        "action" : [
                          {
                            "title" : "-"
                          }
                        ]
                      },
                      //  none
                      {
                        "title" : "12",
                        "timingTiming" : //  12 months
                        {
                          "repeat" : {
                            "boundsRange" : {
                              "low" : {
                                "value" : 12,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              },
                              "high" : {
                                "value" : 12,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              }
                            },
                            "frequency" : 1
                          }
                        },
                        "action" : [
                          {
                            "title" : "-"
                          }
                        ]
                      },
                      //  none
                      {
                        "title" : "18",
                        "timingTiming" : //  18 months
                        {
                          "repeat" : {
                            "boundsRange" : {
                              "low" : {
                                "value" : 18,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              },
                              "high" : {
                                "value" : 18,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              }
                            },
                            "frequency" : 1
                          }
                        },
                        "action" : [
                          {
                            "title" : "-"
                          }
                        ]
                      },
                      //  none
                      {
                        "title" : "24",
                        "timingTiming" : //  24 months
                        {
                          "repeat" : {
                            "boundsRange" : {
                              "low" : {
                                "value" : 24,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              },
                              "high" : {
                                "value" : 24,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              }
                            },
                            "frequency" : 1
                          }
                        },
                        "action" : [
                          {
                            "title" : "-"
                          }
                        ]
                      },
                      //  none
                      {
                        "title" : "36",
                        "timingTiming" : {
                          "repeat" : {
                            "boundsRange" : {
                              "low" : {
                                "value" : 36,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              },
                              "high" : {
                                "value" : 36,
                                "unit" : "months",
                                "system" : "http://unitsofmeasure.org",
                                "code" : "mo"
                              }
                            },
                            "frequency" : 1
                          }
                        },
                        "action" : [
                          {
                            "title" : "-"
                          }
                        ]
                      }
                    ]
                  }
                ]
              }
            ]
          }
        },
        //  36 months
        //  end of long term
        {
          "fullUrl" : "urn:uuid:643d8b44-71f4-2b58-07e8-51c22b294b25",
          "resource" : {
            "resourceType" : "SpecimenDefinition",
            "id" : "643d8b44-71f4-2b58-07e8-51c22b294b25",
            "text" : // specimenDefStoredAt30
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"SpecimenDefinition_643d8b44-71f4-2b58-07e8-51c22b294b25\"> </a><p><b>Generated Narrative: SpecimenDefinition</b><a name=\"643d8b44-71f4-2b58-07e8-51c22b294b25\"> </a><a name=\"hc643d8b44-71f4-2b58-07e8-51c22b294b25\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource SpecimenDefinition &quot;643d8b44-71f4-2b58-07e8-51c22b294b25&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/SpecimenDefinition/643d8b44-71f4-2b58-07e8-51c22b294b25</code></p><p><b>status</b>: active</p><blockquote><p><b>typeTested</b></p><p><b>preference</b>: preferred</p><h3>Handlings</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Instruction</b></td></tr><tr><td style=\"display: none\">*</td><td>30°C/65% RH</td></tr></table></blockquote></div>"
            },
            "url" : "http://example-server.com/fhir/SpecimenDefinition/643d8b44-71f4-2b58-07e8-51c22b294b25",
            "status" : "active",
            "typeTested" : [
              // <meta>
                        <profile value="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/SpecimenDefinition-drug-pq"/>
                    </meta>
              // http://example-server.com/fhir/SpecimenDefinition/643d8b44-71f4-2b58-07e8-51c22b294b25
              {
                "preference" : "preferred",
                "handling" : [
                  //  easier than temp range? which doesnt have humidity
                  {
                    "instruction" : "30°C/65% RH"
                  }
                ]
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:10d7b693-7a0e-2f71-9a10-642e5a0a5d42",
          "resource" : {
            "resourceType" : "ActivityDefinition",
            "id" : "10d7b693-7a0e-2f71-9a10-642e5a0a5d42",
            "text" : // activityLongTerm30XY-Initial
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ActivityDefinition_10d7b693-7a0e-2f71-9a10-642e5a0a5d42\"> </a><p><b>Generated Narrative: ActivityDefinition</b><a name=\"10d7b693-7a0e-2f71-9a10-642e5a0a5d42\"> </a><a name=\"hc10d7b693-7a0e-2f71-9a10-642e5a0a5d42\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ActivityDefinition &quot;10d7b693-7a0e-2f71-9a10-642e5a0a5d42&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ActivityDefinition/10d7b693-7a0e-2f71-9a10-642e5a0a5d42</code></p><p><b>title</b>: Long-term - 30°C/65% RH - XY</p><p><b>status</b>: active</p><p><b>observationRequirement</b>: <a href=\"http://example-server.com/fhir/ObservationDefinition/18762cff-9e29-6e71-1184-e9202fee8cba\">http://example-server.com/fhir/ObservationDefinition/18762cff-9e29-6e71-1184-e9202fee8cba</a>, <a href=\"http://example-server.com/fhir/ObservationDefinition/31abea79-81da-17f8-9d8c-94e9bb75876e\">http://example-server.com/fhir/ObservationDefinition/31abea79-81da-17f8-9d8c-94e9bb75876e</a></p></div>"
            },
            "url" : "http://example-server.com/fhir/ActivityDefinition/10d7b693-7a0e-2f71-9a10-642e5a0a5d42",
            "title" : "Long-term - 30°C/65% RH - XY",
            "status" : "active",
            "observationRequirement" : [
              "http://example-server.com/fhir/ObservationDefinition/18762cff-9e29-6e71-1184-e9202fee8cba",
              "http://example-server.com/fhir/ObservationDefinition/31abea79-81da-17f8-9d8c-94e9bb75876e"
            ]
          }
        },
        // http://example-server.com/fhir/ActivityDefinition/10d7b693-7a0e-2f71-9a10-642e5a0a5d42
        // ObservationDefinition/longTerm30X
        // ObservationDefinition/longTerm30Y
        {
          "fullUrl" : "urn:uuid:480a61f8-14b3-233e-8e5f-7f0db9696a1e",
          "resource" : {
            "resourceType" : "ActivityDefinition",
            "id" : "480a61f8-14b3-233e-8e5f-7f0db9696a1e",
            "text" : // activityLongTerm30X-3
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ActivityDefinition_480a61f8-14b3-233e-8e5f-7f0db9696a1e\"> </a><p><b>Generated Narrative: ActivityDefinition</b><a name=\"480a61f8-14b3-233e-8e5f-7f0db9696a1e\"> </a><a name=\"hc480a61f8-14b3-233e-8e5f-7f0db9696a1e\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ActivityDefinition &quot;480a61f8-14b3-233e-8e5f-7f0db9696a1e&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ActivityDefinition/480a61f8-14b3-233e-8e5f-7f0db9696a1e</code></p><p><b>title</b>: Long-term - 30°C/65% RH - X</p><p><b>status</b>: active</p><p><b>observationRequirement</b>: <a href=\"http://example-server.com/fhir/ObservationDefinition/18762cff-9e29-6e71-1184-e9202fee8cba\">http://example-server.com/fhir/ObservationDefinition/18762cff-9e29-6e71-1184-e9202fee8cba</a></p></div>"
            },
            "url" : "http://example-server.com/fhir/ActivityDefinition/480a61f8-14b3-233e-8e5f-7f0db9696a1e",
            "title" : "Long-term - 30°C/65% RH - X",
            "status" : "active",
            "observationRequirement" : [
              "http://example-server.com/fhir/ObservationDefinition/18762cff-9e29-6e71-1184-e9202fee8cba"
            ]
          }
        },
        // http://example-server.com/fhir/ActivityDefinition/480a61f8-14b3-233e-8e5f-7f0db9696a1e
        // ObservationDefinition/longTerm30X
        {
          "fullUrl" : "urn:uuid:bee486c4-6ab5-6293-4114-d4be24f303d3",
          "resource" : {
            "resourceType" : "ActivityDefinition",
            "id" : "bee486c4-6ab5-6293-4114-d4be24f303d3",
            "text" : // activityLongTerm30X-6
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ActivityDefinition_bee486c4-6ab5-6293-4114-d4be24f303d3\"> </a><p><b>Generated Narrative: ActivityDefinition</b><a name=\"bee486c4-6ab5-6293-4114-d4be24f303d3\"> </a><a name=\"hcbee486c4-6ab5-6293-4114-d4be24f303d3\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ActivityDefinition &quot;bee486c4-6ab5-6293-4114-d4be24f303d3&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ActivityDefinition/bee486c4-6ab5-6293-4114-d4be24f303d3</code></p><p><b>title</b>: Long-term - 30°C/65% RH - X</p><p><b>status</b>: active</p><p><b>observationRequirement</b>: <a href=\"http://example-server.com/fhir/ObservationDefinition/18762cff-9e29-6e71-1184-e9202fee8cba\">http://example-server.com/fhir/ObservationDefinition/18762cff-9e29-6e71-1184-e9202fee8cba</a></p></div>"
            },
            "url" : "http://example-server.com/fhir/ActivityDefinition/bee486c4-6ab5-6293-4114-d4be24f303d3",
            "title" : "Long-term - 30°C/65% RH - X",
            "status" : "active",
            "observationRequirement" : [
              "http://example-server.com/fhir/ObservationDefinition/18762cff-9e29-6e71-1184-e9202fee8cba"
            ]
          }
        },
        // http://example-server.com/fhir/ActivityDefinition/bee486c4-6ab5-6293-4114-d4be24f303d3
        // ObservationDefinition/longTerm30X
        {
          "fullUrl" : "urn:uuid:99893d3c-520c-8d7b-6d73-f46b1a662201",
          "resource" : {
            "resourceType" : "ActivityDefinition",
            "id" : "99893d3c-520c-8d7b-6d73-f46b1a662201",
            "text" : // activityLongTerm30X-9
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ActivityDefinition_99893d3c-520c-8d7b-6d73-f46b1a662201\"> </a><p><b>Generated Narrative: ActivityDefinition</b><a name=\"99893d3c-520c-8d7b-6d73-f46b1a662201\"> </a><a name=\"hc99893d3c-520c-8d7b-6d73-f46b1a662201\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ActivityDefinition &quot;99893d3c-520c-8d7b-6d73-f46b1a662201&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ActivityDefinition/99893d3c-520c-8d7b-6d73-f46b1a662201</code></p><p><b>title</b>: Long-term - 30°C/65% RH - X</p><p><b>status</b>: active</p><p><b>observationRequirement</b>: <a href=\"http://example-server.com/fhir/ObservationDefinition/18762cff-9e29-6e71-1184-e9202fee8cba\">http://example-server.com/fhir/ObservationDefinition/18762cff-9e29-6e71-1184-e9202fee8cba</a></p></div>"
            },
            "url" : "http://example-server.com/fhir/ActivityDefinition/99893d3c-520c-8d7b-6d73-f46b1a662201",
            "title" : "Long-term - 30°C/65% RH - X",
            "status" : "active",
            "observationRequirement" : [
              "http://example-server.com/fhir/ObservationDefinition/18762cff-9e29-6e71-1184-e9202fee8cba"
            ]
          }
        },
        // http://example-server.com/fhir/ActivityDefinition/99893d3c-520c-8d7b-6d73-f46b1a662201
        // ObservationDefinition/longTerm30X
        {
          "fullUrl" : "urn:uuid:b3254b8e-6fc3-88d3-7d38-0afcf13c4f67",
          "resource" : {
            "resourceType" : "ActivityDefinition",
            "id" : "b3254b8e-6fc3-88d3-7d38-0afcf13c4f67",
            "text" : // activityLongTerm30X-12
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ActivityDefinition_b3254b8e-6fc3-88d3-7d38-0afcf13c4f67\"> </a><p><b>Generated Narrative: ActivityDefinition</b><a name=\"b3254b8e-6fc3-88d3-7d38-0afcf13c4f67\"> </a><a name=\"hcb3254b8e-6fc3-88d3-7d38-0afcf13c4f67\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ActivityDefinition &quot;b3254b8e-6fc3-88d3-7d38-0afcf13c4f67&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ActivityDefinition/b3254b8e-6fc3-88d3-7d38-0afcf13c4f67</code></p><p><b>title</b>: Long-term - 30°C/65% RH - X</p><p><b>status</b>: active</p><p><b>observationRequirement</b>: <a href=\"http://example-server.com/fhir/ObservationDefinition/18762cff-9e29-6e71-1184-e9202fee8cba\">http://example-server.com/fhir/ObservationDefinition/18762cff-9e29-6e71-1184-e9202fee8cba</a></p></div>"
            },
            "url" : "http://example-server.com/fhir/ActivityDefinition/b3254b8e-6fc3-88d3-7d38-0afcf13c4f67",
            "title" : "Long-term - 30°C/65% RH - X",
            "status" : "active",
            "observationRequirement" : [
              "http://example-server.com/fhir/ObservationDefinition/18762cff-9e29-6e71-1184-e9202fee8cba"
            ]
          }
        },
        // http://example-server.com/fhir/ActivityDefinition/b3254b8e-6fc3-88d3-7d38-0afcf13c4f67
        // ObservationDefinition/longTerm30X
        {
          "fullUrl" : "urn:uuid:c9b53a46-2f61-7b3f-5780-5f5c79a47f12",
          "resource" : {
            "resourceType" : "ActivityDefinition",
            "id" : "c9b53a46-2f61-7b3f-5780-5f5c79a47f12",
            "text" : // activityLongTerm30X-18
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ActivityDefinition_c9b53a46-2f61-7b3f-5780-5f5c79a47f12\"> </a><p><b>Generated Narrative: ActivityDefinition</b><a name=\"c9b53a46-2f61-7b3f-5780-5f5c79a47f12\"> </a><a name=\"hcc9b53a46-2f61-7b3f-5780-5f5c79a47f12\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ActivityDefinition &quot;c9b53a46-2f61-7b3f-5780-5f5c79a47f12&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ActivityDefinition/c9b53a46-2f61-7b3f-5780-5f5c79a47f12</code></p><p><b>title</b>: Long-term - 30°C/65% RH - X</p><p><b>status</b>: active</p><p><b>observationRequirement</b>: <a href=\"http://example-server.com/fhir/ObservationDefinition/18762cff-9e29-6e71-1184-e9202fee8cba\">http://example-server.com/fhir/ObservationDefinition/18762cff-9e29-6e71-1184-e9202fee8cba</a></p></div>"
            },
            "url" : "http://example-server.com/fhir/ActivityDefinition/c9b53a46-2f61-7b3f-5780-5f5c79a47f12",
            "title" : "Long-term - 30°C/65% RH - X",
            "status" : "active",
            "observationRequirement" : [
              "http://example-server.com/fhir/ObservationDefinition/18762cff-9e29-6e71-1184-e9202fee8cba"
            ]
          }
        },
        // http://example-server.com/fhir/ActivityDefinition/c9b53a46-2f61-7b3f-5780-5f5c79a47f12
        // ObservationDefinition/longTerm30X
        {
          "fullUrl" : "urn:uuid:d6f7de9d-57a5-6a2c-1c2f-0d65718860f2",
          "resource" : {
            "resourceType" : "ActivityDefinition",
            "id" : "d6f7de9d-57a5-6a2c-1c2f-0d65718860f2",
            "text" : // activityLongTerm30X-24
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ActivityDefinition_d6f7de9d-57a5-6a2c-1c2f-0d65718860f2\"> </a><p><b>Generated Narrative: ActivityDefinition</b><a name=\"d6f7de9d-57a5-6a2c-1c2f-0d65718860f2\"> </a><a name=\"hcd6f7de9d-57a5-6a2c-1c2f-0d65718860f2\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ActivityDefinition &quot;d6f7de9d-57a5-6a2c-1c2f-0d65718860f2&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ActivityDefinition/d6f7de9d-57a5-6a2c-1c2f-0d65718860f2</code></p><p><b>title</b>: Long-term - 30°C/65% RH - X</p><p><b>status</b>: active</p><p><b>observationRequirement</b>: <a href=\"http://example-server.com/fhir/ObservationDefinition/18762cff-9e29-6e71-1184-e9202fee8cba\">http://example-server.com/fhir/ObservationDefinition/18762cff-9e29-6e71-1184-e9202fee8cba</a></p></div>"
            },
            "url" : "http://example-server.com/fhir/ActivityDefinition/d6f7de9d-57a5-6a2c-1c2f-0d65718860f2",
            "title" : "Long-term - 30°C/65% RH - X",
            "status" : "active",
            "observationRequirement" : [
              "http://example-server.com/fhir/ObservationDefinition/18762cff-9e29-6e71-1184-e9202fee8cba"
            ]
          }
        },
        // http://example-server.com/fhir/ActivityDefinition/d6f7de9d-57a5-6a2c-1c2f-0d65718860f2
        // ObservationDefinition/longTerm30X
        {
          "fullUrl" : "urn:uuid:75073965-82eb-407d-34cf-3a7767a38149",
          "resource" : {
            "resourceType" : "ActivityDefinition",
            "id" : "75073965-82eb-407d-34cf-3a7767a38149",
            "text" : // activityLongTerm30X-36
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ActivityDefinition_75073965-82eb-407d-34cf-3a7767a38149\"> </a><p><b>Generated Narrative: ActivityDefinition</b><a name=\"75073965-82eb-407d-34cf-3a7767a38149\"> </a><a name=\"hc75073965-82eb-407d-34cf-3a7767a38149\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ActivityDefinition &quot;75073965-82eb-407d-34cf-3a7767a38149&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ActivityDefinition/75073965-82eb-407d-34cf-3a7767a38149</code></p><p><b>title</b>: Long-term - 30°C/65% RH - X</p><p><b>status</b>: active</p><p><b>observationRequirement</b>: <a href=\"http://example-server.com/fhir/ObservationDefinition/18762cff-9e29-6e71-1184-e9202fee8cba\">http://example-server.com/fhir/ObservationDefinition/18762cff-9e29-6e71-1184-e9202fee8cba</a></p></div>"
            },
            "url" : "http://example-server.com/fhir/ActivityDefinition/75073965-82eb-407d-34cf-3a7767a38149",
            "title" : "Long-term - 30°C/65% RH - X",
            "status" : "active",
            "observationRequirement" : [
              "http://example-server.com/fhir/ObservationDefinition/18762cff-9e29-6e71-1184-e9202fee8cba"
            ]
          }
        },
        // http://example-server.com/fhir/ActivityDefinition/75073965-82eb-407d-34cf-3a7767a38149
        // ObservationDefinition/longTerm30X
        {
          "fullUrl" : "urn:uuid:18762cff-9e29-6e71-1184-e9202fee8cba",
          "resource" : //  can have others
          {
            "resourceType" : "ObservationDefinition",
            "id" : "18762cff-9e29-6e71-1184-e9202fee8cba",
            "text" : // longTerm30X
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_18762cff-9e29-6e71-1184-e9202fee8cba\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"18762cff-9e29-6e71-1184-e9202fee8cba\"> </a><a name=\"hc18762cff-9e29-6e71-1184-e9202fee8cba\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;18762cff-9e29-6e71-1184-e9202fee8cba&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/18762cff-9e29-6e71-1184-e9202fee8cba</code></p><p><b>title</b>: X</p><p><b>status</b>: active</p><p><b>code</b>: Battery of tests 'X' at 30°C/65% RH <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>specimen</b>: See on this page: SpecimenDefinition/643d8b44-71f4-2b58-07e8-51c22b294b25</p><p><b>hasMember</b>: </p><ul><li>See on this page: ObservationDefinition/559ffdc3-349b-a4a3-a651-ce2715f08d69</li><li>See on this page: ObservationDefinition/7943795a-2abe-666f-545f-133e23b97119</li><li>See on this page: ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</li></ul></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/18762cff-9e29-6e71-1184-e9202fee8cba",
            "title" : "X",
            "status" : "active",
            "code" : // <meta>
                        <profile value="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/ObservationDefinition-test-method-drug-pq"/>
                    </meta>
            // http://example-server.com/fhir/ObservationDefinition/18762cff-9e29-6e71-1184-e9202fee8cba
            {
              "text" : "Battery of tests 'X' at 30°C/65% RH"
            },
            "specimen" : [
              {
                "reference" : "SpecimenDefinition/643d8b44-71f4-2b58-07e8-51c22b294b25"
              }
            ],
            "hasMember" : [
              // SpecimenDefinition/specimenDefStoredAt30
              {
                "reference" : "ObservationDefinition/559ffdc3-349b-a4a3-a651-ce2715f08d69"
              },
              // ObservationDefinition/Description
              {
                "reference" : "ObservationDefinition/7943795a-2abe-666f-545f-133e23b97119"
              },
              // ObservationDefinition/Assay
              {
                "reference" : "ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e"
              }
            ]
          }
        },
        // ObservationDefinition/Impurities
        {
          "fullUrl" : "urn:uuid:559ffdc3-349b-a4a3-a651-ce2715f08d69",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "559ffdc3-349b-a4a3-a651-ce2715f08d69",
            "text" : // Description
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_559ffdc3-349b-a4a3-a651-ce2715f08d69\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"559ffdc3-349b-a4a3-a651-ce2715f08d69\"> </a><a name=\"hc559ffdc3-349b-a4a3-a651-ce2715f08d69\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;559ffdc3-349b-a4a3-a651-ce2715f08d69&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/559ffdc3-349b-a4a3-a651-ce2715f08d69</code></p><p><b>title</b>: Description</p><p><b>status</b>: active</p><p><b>code</b>: Description <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DESC)</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td></tr><tr><td style=\"display: none\">*</td><td/></tr></table></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/559ffdc3-349b-a4a3-a651-ce2715f08d69",
            "title" : "Description",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/559ffdc3-349b-a4a3-a651-ce2715f08d69
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "DESC",
                  "display" : "Description"
                }
              ],
              "text" : "Description"
            },
            "qualifiedValue" : [
              {
                "extension" : [
                  {
                    "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-text-pq",
                    "valueString" : "A white to brown powder"
                  }
                ]
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:7943795a-2abe-666f-545f-133e23b97119",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "7943795a-2abe-666f-545f-133e23b97119",
            "text" : // Assay
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_7943795a-2abe-666f-545f-133e23b97119\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"7943795a-2abe-666f-545f-133e23b97119\"> </a><a name=\"hc7943795a-2abe-666f-545f-133e23b97119\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;7943795a-2abe-666f-545f-133e23b97119&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/7943795a-2abe-666f-545f-133e23b97119</code></p><p><b>title</b>: Assay (% w/w) (Mean)</p><p><b>status</b>: active</p><p><b>code</b>: Assay (% w/w) (Mean) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#ASSAY &quot;Assay&quot;)</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>98-102 % w/w</td></tr></table></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/7943795a-2abe-666f-545f-133e23b97119",
            "title" : "Assay (% w/w) (Mean)",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/7943795a-2abe-666f-545f-133e23b97119
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "ASSAY",
                  "display" : "Assay"
                }
              ],
              "text" : "Assay (% w/w) (Mean)"
            },
            "qualifiedValue" : [
              {
                "range" : {
                  "low" : {
                    "value" : 98,
                    "unit" : "% w/w",
                    "system" : "http://unitsofmeasure.org",
                    "code" : "%"
                  },
                  "high" : {
                    "value" : 102,
                    "unit" : "% w/w",
                    "system" : "http://unitsofmeasure.org",
                    "code" : "%"
                  }
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:73d9d304-a0b8-31b6-1165-346563b9305e",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "73d9d304-a0b8-31b6-1165-346563b9305e",
            "text" : // Impurities
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_73d9d304-a0b8-31b6-1165-346563b9305e\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"73d9d304-a0b8-31b6-1165-346563b9305e\"> </a><a name=\"hc73d9d304-a0b8-31b6-1165-346563b9305e\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;73d9d304-a0b8-31b6-1165-346563b9305e&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</code></p><p><b>title</b>: Drug-related Impurities Content by LC (% w/w)</p><p><b>status</b>: active</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>range</b>: ?-0.5</p></blockquote><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: Impurity 2 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>range</b>: ?-0.52</p></blockquote><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: Any Unspecified Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>range</b>: ?-0.10</p></blockquote><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: Total Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>range</b>: ?-2.0</p></blockquote><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td></tr></table></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e",
            "title" : "Drug-related Impurities Content by LC (% w/w)",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Impurities",
                  "display" : "Impurities"
                }
              ]
            },
            "qualifiedValue" : [
              {
                "appliesTo" : [
                  {
                    "text" : "Impurity"
                  }
                ],
                "range" : //  could be a code
                {
                  "high" : {
                    "value" : 0.5,
                    "unit" : "% w/w",
                    "system" : "http://unitsofmeasure.org",
                    "code" : "%"
                  }
                }
              },
              {
                "appliesTo" : [
                  {
                    "text" : "Impurity 2"
                  }
                ],
                "range" : {
                  "high" : {
                    "value" : 0.52,
                    "unit" : "% w/w",
                    "system" : "http://unitsofmeasure.org",
                    "code" : "%"
                  }
                }
              },
              {
                "appliesTo" : [
                  {
                    "text" : "Any Unspecified Impurity"
                  }
                ],
                "range" : {
                  "high" : {
                    "value" : 0.10,
                    "unit" : "% w/w",
                    "system" : "http://unitsofmeasure.org",
                    "code" : "%"
                  }
                }
              },
              {
                "appliesTo" : [
                  {
                    "text" : "Total Impurities"
                  }
                ],
                "range" : {
                  "high" : {
                    "value" : 2.0,
                    "unit" : "% w/w",
                    "system" : "http://unitsofmeasure.org",
                    "code" : "%"
                  }
                }
              }
            ],
            "component" : [
              {
                "code" : //  are expected to have a component that says what impurity this one is
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "IMP",
                      "display" : "Impurity"
                    }
                  ]
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:31abea79-81da-17f8-9d8c-94e9bb75876e",
          "resource" : //  can have others
          {
            "resourceType" : "ObservationDefinition",
            "id" : "31abea79-81da-17f8-9d8c-94e9bb75876e",
            "text" : // longTerm30Y
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_31abea79-81da-17f8-9d8c-94e9bb75876e\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"31abea79-81da-17f8-9d8c-94e9bb75876e\"> </a><a name=\"hc31abea79-81da-17f8-9d8c-94e9bb75876e\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;31abea79-81da-17f8-9d8c-94e9bb75876e&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/31abea79-81da-17f8-9d8c-94e9bb75876e</code></p><p><b>title</b>: Y</p><p><b>status</b>: active</p><p><b>code</b>: Battery of tests 'Y' at 30°C/65% RH <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>specimen</b>: See on this page: SpecimenDefinition/643d8b44-71f4-2b58-07e8-51c22b294b25</p><p><b>hasMember</b>: See on this page: ObservationDefinition/6b96124b-1a44-0b6b-6783-d6c49360230b</p></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/31abea79-81da-17f8-9d8c-94e9bb75876e",
            "title" : "Y",
            "status" : "active",
            "code" : // <meta>
                        <profile value="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/ObservationDefinition-test-method-drug-pq"/>
                    </meta>
            // http://example-server.com/fhir/ObservationDefinition/31abea79-81da-17f8-9d8c-94e9bb75876e
            {
              "text" : "Battery of tests 'Y' at 30°C/65% RH"
            },
            "specimen" : [
              {
                "reference" : "SpecimenDefinition/643d8b44-71f4-2b58-07e8-51c22b294b25"
              }
            ],
            "hasMember" : [
              // SpecimenDefinition/specimenDefStoredAt30
              {
                "reference" : "ObservationDefinition/6b96124b-1a44-0b6b-6783-d6c49360230b"
              }
            ]
          }
        },
        // ObservationDefinition/Identification
        {
          "fullUrl" : "urn:uuid:6b96124b-1a44-0b6b-6783-d6c49360230b",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "6b96124b-1a44-0b6b-6783-d6c49360230b",
            "text" : // Identification
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_6b96124b-1a44-0b6b-6783-d6c49360230b\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"6b96124b-1a44-0b6b-6783-d6c49360230b\"> </a><a name=\"hc6b96124b-1a44-0b6b-6783-d6c49360230b\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;6b96124b-1a44-0b6b-6783-d6c49360230b&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/6b96124b-1a44-0b6b-6783-d6c49360230b</code></p><p><b>title</b>: Identification</p><p><b>status</b>: active</p><p><b>code</b>: Identification <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IDT)</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td></tr><tr><td style=\"display: none\">*</td><td/></tr></table></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/6b96124b-1a44-0b6b-6783-d6c49360230b",
            "title" : "Identification",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/6b96124b-1a44-0b6b-6783-d6c49360230b
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "IDT",
                  "display" : "Identification"
                }
              ],
              "text" : "Identification"
            },
            "qualifiedValue" : [
              {
                "extension" : [
                  {
                    "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-text-pq",
                    "valueString" : "Complies"
                  }
                ]
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:306637ec-1041-80e8-8e77-e7ca814253e1",
          "resource" : {
            "resourceType" : "SpecimenDefinition",
            "id" : "306637ec-1041-80e8-8e77-e7ca814253e1",
            "text" : // specimenDefStoredAt40
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"SpecimenDefinition_306637ec-1041-80e8-8e77-e7ca814253e1\"> </a><p><b>Generated Narrative: SpecimenDefinition</b><a name=\"306637ec-1041-80e8-8e77-e7ca814253e1\"> </a><a name=\"hc306637ec-1041-80e8-8e77-e7ca814253e1\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource SpecimenDefinition &quot;306637ec-1041-80e8-8e77-e7ca814253e1&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/SpecimenDefinition/306637ec-1041-80e8-8e77-e7ca814253e1</code></p><p><b>status</b>: active</p><blockquote><p><b>typeTested</b></p><p><b>preference</b>: preferred</p><h3>Handlings</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Instruction</b></td></tr><tr><td style=\"display: none\">*</td><td>40°C/75% RH</td></tr></table></blockquote></div>"
            },
            "url" : "http://example-server.com/fhir/SpecimenDefinition/306637ec-1041-80e8-8e77-e7ca814253e1",
            "status" : "active",
            "typeTested" : [
              // <meta>
                        <profile value="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/SpecimenDefinition-drug-pq"/>
                    </meta>
              // http://example-server.com/fhir/SpecimenDefinition/306637ec-1041-80e8-8e77-e7ca814253e1
              {
                "preference" : "preferred",
                "handling" : [
                  {
                    "instruction" : "40°C/75% RH"
                  }
                ]
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:1b43a536-3c29-3427-0b93-e35866ef8495",
          "resource" : {
            "resourceType" : "ActivityDefinition",
            "id" : "1b43a536-3c29-3427-0b93-e35866ef8495",
            "text" : // activityAccelerated40XY-Initial
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ActivityDefinition_1b43a536-3c29-3427-0b93-e35866ef8495\"> </a><p><b>Generated Narrative: ActivityDefinition</b><a name=\"1b43a536-3c29-3427-0b93-e35866ef8495\"> </a><a name=\"hc1b43a536-3c29-3427-0b93-e35866ef8495\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ActivityDefinition &quot;1b43a536-3c29-3427-0b93-e35866ef8495&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ActivityDefinition/1b43a536-3c29-3427-0b93-e35866ef8495</code></p><p><b>title</b>: Accelerated - 40°C/70% RH - XY</p><p><b>status</b>: active</p><p><b>observationRequirement</b>: <a href=\"http://example-server.com/fhir/ObservationDefinition/35fa7b97-98d3-35d3-5672-4ab1047d57fc\">http://example-server.com/fhir/ObservationDefinition/35fa7b97-98d3-35d3-5672-4ab1047d57fc</a>, <a href=\"http://example-server.com/fhir/ObservationDefinition/accb8802-4223-61e2-8c79-2282e22a2bb6\">http://example-server.com/fhir/ObservationDefinition/accb8802-4223-61e2-8c79-2282e22a2bb6</a></p></div>"
            },
            "url" : "http://example-server.com/fhir/ActivityDefinition/1b43a536-3c29-3427-0b93-e35866ef8495",
            "title" : "Accelerated - 40°C/70% RH - XY",
            "status" : "active",
            "observationRequirement" : [
              "http://example-server.com/fhir/ObservationDefinition/35fa7b97-98d3-35d3-5672-4ab1047d57fc",
              "http://example-server.com/fhir/ObservationDefinition/accb8802-4223-61e2-8c79-2282e22a2bb6"
            ]
          }
        },
        // http://example-server.com/fhir/ActivityDefinition/1b43a536-3c29-3427-0b93-e35866ef8495
        // ObservationDefinition/accelerated40X
        // ObservationDefinition/accelerated40Y
        {
          "fullUrl" : "urn:uuid:8a453cd8-1ac3-4c86-48c3-3e5ea9ee76a9",
          "resource" : {
            "resourceType" : "ActivityDefinition",
            "id" : "8a453cd8-1ac3-4c86-48c3-3e5ea9ee76a9",
            "text" : // activityAccelerated40X-3
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ActivityDefinition_8a453cd8-1ac3-4c86-48c3-3e5ea9ee76a9\"> </a><p><b>Generated Narrative: ActivityDefinition</b><a name=\"8a453cd8-1ac3-4c86-48c3-3e5ea9ee76a9\"> </a><a name=\"hc8a453cd8-1ac3-4c86-48c3-3e5ea9ee76a9\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ActivityDefinition &quot;8a453cd8-1ac3-4c86-48c3-3e5ea9ee76a9&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ActivityDefinition/8a453cd8-1ac3-4c86-48c3-3e5ea9ee76a9</code></p><p><b>title</b>: Accelerated - 40°C/70% RH - X</p><p><b>status</b>: active</p><p><b>observationRequirement</b>: <a href=\"http://example-server.com/fhir/ObservationDefinition/35fa7b97-98d3-35d3-5672-4ab1047d57fc\">http://example-server.com/fhir/ObservationDefinition/35fa7b97-98d3-35d3-5672-4ab1047d57fc</a></p></div>"
            },
            "url" : "http://example-server.com/fhir/ActivityDefinition/8a453cd8-1ac3-4c86-48c3-3e5ea9ee76a9",
            "title" : "Accelerated - 40°C/70% RH - X",
            "status" : "active",
            "observationRequirement" : [
              "http://example-server.com/fhir/ObservationDefinition/35fa7b97-98d3-35d3-5672-4ab1047d57fc"
            ]
          }
        },
        // http://example-server.com/fhir/ActivityDefinition/8a453cd8-1ac3-4c86-48c3-3e5ea9ee76a9
        // ObservationDefinition/accelerated40X
        {
          "fullUrl" : "urn:uuid:cf2f00df-971f-0bab-8768-4251b1ad0817",
          "resource" : {
            "resourceType" : "ActivityDefinition",
            "id" : "cf2f00df-971f-0bab-8768-4251b1ad0817",
            "text" : // activityAccelerated40X-6
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ActivityDefinition_cf2f00df-971f-0bab-8768-4251b1ad0817\"> </a><p><b>Generated Narrative: ActivityDefinition</b><a name=\"cf2f00df-971f-0bab-8768-4251b1ad0817\"> </a><a name=\"hccf2f00df-971f-0bab-8768-4251b1ad0817\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ActivityDefinition &quot;cf2f00df-971f-0bab-8768-4251b1ad0817&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ActivityDefinition/cf2f00df-971f-0bab-8768-4251b1ad0817</code></p><p><b>title</b>: Accelerated - 40°C/70% RH - X</p><p><b>status</b>: active</p><p><b>observationRequirement</b>: <a href=\"http://example-server.com/fhir/ObservationDefinition/35fa7b97-98d3-35d3-5672-4ab1047d57fc\">http://example-server.com/fhir/ObservationDefinition/35fa7b97-98d3-35d3-5672-4ab1047d57fc</a></p></div>"
            },
            "url" : "http://example-server.com/fhir/ActivityDefinition/cf2f00df-971f-0bab-8768-4251b1ad0817",
            "title" : "Accelerated - 40°C/70% RH - X",
            "status" : "active",
            "observationRequirement" : [
              "http://example-server.com/fhir/ObservationDefinition/35fa7b97-98d3-35d3-5672-4ab1047d57fc"
            ]
          }
        },
        // http://example-server.com/fhir/ActivityDefinition/cf2f00df-971f-0bab-8768-4251b1ad0817
        // ObservationDefinition/accelerated40X
        {
          "fullUrl" : "urn:uuid:35fa7b97-98d3-35d3-5672-4ab1047d57fc",
          "resource" : //  can have others
          {
            "resourceType" : "ObservationDefinition",
            "id" : "35fa7b97-98d3-35d3-5672-4ab1047d57fc",
            "text" : // accelerated40X
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_35fa7b97-98d3-35d3-5672-4ab1047d57fc\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"35fa7b97-98d3-35d3-5672-4ab1047d57fc\"> </a><a name=\"hc35fa7b97-98d3-35d3-5672-4ab1047d57fc\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;35fa7b97-98d3-35d3-5672-4ab1047d57fc&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/35fa7b97-98d3-35d3-5672-4ab1047d57fc</code></p><p><b>title</b>: X</p><p><b>status</b>: active</p><p><b>code</b>: Battery of tests 'X' at 40°C/75% RH <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>specimen</b>: See on this page: SpecimenDefinition/306637ec-1041-80e8-8e77-e7ca814253e1</p><p><b>hasMember</b>: </p><ul><li>See on this page: ObservationDefinition/559ffdc3-349b-a4a3-a651-ce2715f08d69</li><li>See on this page: ObservationDefinition/7943795a-2abe-666f-545f-133e23b97119</li></ul></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/35fa7b97-98d3-35d3-5672-4ab1047d57fc",
            "title" : "X",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/35fa7b97-98d3-35d3-5672-4ab1047d57fc
            {
              "text" : "Battery of tests 'X' at 40°C/75% RH"
            },
            "specimen" : [
              {
                "reference" : "SpecimenDefinition/306637ec-1041-80e8-8e77-e7ca814253e1"
              }
            ],
            "hasMember" : [
              // SpecimenDefinition/specimenDefStoredAt40
              {
                "reference" : "ObservationDefinition/559ffdc3-349b-a4a3-a651-ce2715f08d69"
              },
              // ObservationDefinition/Description
              {
                "reference" : "ObservationDefinition/7943795a-2abe-666f-545f-133e23b97119"
              }
            ]
          }
        },
        // ObservationDefinition/Assay
        {
          "fullUrl" : "urn:uuid:accb8802-4223-61e2-8c79-2282e22a2bb6",
          "resource" : //  can have others
          {
            "resourceType" : "ObservationDefinition",
            "id" : "accb8802-4223-61e2-8c79-2282e22a2bb6",
            "text" : // accelerated40Y
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_accb8802-4223-61e2-8c79-2282e22a2bb6\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"accb8802-4223-61e2-8c79-2282e22a2bb6\"> </a><a name=\"hcaccb8802-4223-61e2-8c79-2282e22a2bb6\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;accb8802-4223-61e2-8c79-2282e22a2bb6&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/accb8802-4223-61e2-8c79-2282e22a2bb6</code></p><p><b>title</b>: Y</p><p><b>status</b>: active</p><p><b>code</b>: Battery of tests 'Y' at 40°C/75% RH <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>specimen</b>: See on this page: SpecimenDefinition/306637ec-1041-80e8-8e77-e7ca814253e1</p><p><b>hasMember</b>: See on this page: ObservationDefinition/6b96124b-1a44-0b6b-6783-d6c49360230b</p></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/accb8802-4223-61e2-8c79-2282e22a2bb6",
            "title" : "Y",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/accb8802-4223-61e2-8c79-2282e22a2bb6
            {
              "text" : "Battery of tests 'Y' at 40°C/75% RH"
            },
            "specimen" : [
              {
                "reference" : "SpecimenDefinition/306637ec-1041-80e8-8e77-e7ca814253e1"
              }
            ],
            "hasMember" : [
              // SpecimenDefinition/specimenDefStoredAt40
              {
                "reference" : "ObservationDefinition/6b96124b-1a44-0b6b-6783-d6c49360230b"
              }
            ]
          }
        },
        // ObservationDefinition/Identification
        {
          "fullUrl" : "urn:uuid:6a5354bf-602c-99f1-324b-0bb5f7e06cd5",
          "resource" : {
            "resourceType" : "Specimen",
            "id" : "6a5354bf-602c-99f1-324b-0bb5f7e06cd5",
            "text" : // stabilityInitial-1
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Specimen_6a5354bf-602c-99f1-324b-0bb5f7e06cd5\"> </a><p><b>Generated Narrative: Specimen</b><a name=\"6a5354bf-602c-99f1-324b-0bb5f7e06cd5\"> </a><a name=\"hc6a5354bf-602c-99f1-324b-0bb5f7e06cd5\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Specimen &quot;6a5354bf-602c-99f1-324b-0bb5f7e06cd5&quot; </p></div><h3>Collections</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Collected[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>2020-06</td></tr></table><blockquote><p><b>processing</b></p><p><b>description</b>: No storage</p></blockquote><blockquote><p><b>processing</b></p><p><b>description</b>: 25°C/60% RH</p></blockquote></div>"
            },
            "collection" : //  when sample first taken, before the timed periods start
            {
              "collectedDateTime" : "2020-06"
            },
            "processing" : [
              {
                "description" : "No storage"
              },
              {
                "description" : "25°C/60% RH"
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:588a6787-0454-55ef-0b8a-4c8941b6976c",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "588a6787-0454-55ef-0b8a-4c8941b6976c",
            "text" : // LongTerm30C-initial-1
            {
              "status" : "extensions",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_588a6787-0454-55ef-0b8a-4c8941b6976c\"> </a><p><b>Generated Narrative: Observation</b><a name=\"588a6787-0454-55ef-0b8a-4c8941b6976c\"> </a><a name=\"hc588a6787-0454-55ef-0b8a-4c8941b6976c\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;588a6787-0454-55ef-0b8a-4c8941b6976c&quot; </p></div><p><b>Triggered by</b>: See on this page: ActivityDefinition/10d7b693-7a0e-2f71-9a10-642e5a0a5d42</p><p><b>status</b>: final</p><p><b>code</b>: Test Components - Long-term 25C etc - Initial (XYZ) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>subject</b>: See on this page: Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>specimen</b>: See on this page: Specimen/6a5354bf-602c-99f1-324b-0bb5f7e06cd5</p><p><b>hasMember</b>: </p><ul><li><a name=\"hcLongTerm30C-initial-1-Description\"> </a></li><li><a name=\"hcLongTerm30C-initial-1-Assay\"> </a></li><li><a name=\"hcLongTerm30C-initial-1-Impurity1\"> </a></li><li><a name=\"hcLongTerm30C-initial-1-Impurity2\"> </a></li><li><a name=\"hcLongTerm30C-initial-1-ImpurityUnspecified\"> </a></li><li><a name=\"hcLongTerm30C-initial-1-ImpurityTotal\"> </a></li><li><a name=\"hcLongTerm30C-initial-1-Identification\"> </a></li></ul><blockquote><p/><p><a name=\"LongTerm30C-initial-1-Description\"> </a></p><p><a name=\"hcLongTerm30C-initial-1-Description\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/559ffdc3-349b-a4a3-a651-ce2715f08d69</p><p><b>status</b>: final</p><p><b>code</b>: Description <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DESC)</span></p><p><b>subject</b>: See on this page: Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><blockquote><p/><p><a name=\"LongTerm30C-initial-1-Assay\"> </a></p><p><a name=\"hcLongTerm30C-initial-1-Assay\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/7943795a-2abe-666f-545f-133e23b97119</p><p><b>status</b>: final</p><p><b>code</b>: Assay <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#ASSAY)</span></p><p><b>subject</b>: See on this page: Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.15 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p></blockquote><blockquote><p/><p><a name=\"LongTerm30C-initial-1-Impurity1\"> </a></p><p><a name=\"hcLongTerm30C-initial-1-Impurity1\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.1 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p/><p><a name=\"LongTerm30C-initial-1-Impurity2\"> </a></p><p><a name=\"hcLongTerm30C-initial-1-Impurity2\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: See on this page: Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.2 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 2 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p/><p><a name=\"LongTerm30C-initial-1-ImpurityUnspecified\"> </a></p><p><a name=\"hcLongTerm30C-initial-1-ImpurityUnspecified\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: See on this page: Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: &lt;0.05 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Any Unspecified Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p/><p><a name=\"LongTerm30C-initial-1-ImpurityTotal\"> </a></p><p><a name=\"hcLongTerm30C-initial-1-ImpurityTotal\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: See on this page: Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.8 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Total Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p/><p><a name=\"LongTerm30C-initial-1-Identification\"> </a></p><p><a name=\"hcLongTerm30C-initial-1-Identification\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/6b96124b-1a44-0b6b-6783-d6c49360230b</p><p><b>status</b>: final</p><p><b>code</b>: Identification <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IDT)</span></p><p><b>subject</b>: See on this page: Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm30C-initial-1-Description</b><a name=\"LongTerm30C-initial-1-Description\"> </a><a name=\"hcLongTerm30C-initial-1-Description\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#ObservationDefinition_559ffdc3-349b-a4a3-a651-ce2715f08d69\">ObservationDefinition/559ffdc3-349b-a4a3-a651-ce2715f08d69</a></p><p><b>status</b>: final</p><p><b>code</b>: Description <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DESC)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#Substance_a3fdc23b-6c16-2e65-481e-3fc895b37b87\">Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-batch-analysis-pq-ex1-prod.html#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\">Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</a></p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm30C-initial-1-Impurity1</b><a name=\"LongTerm30C-initial-1-Impurity1\"> </a><a name=\"hcLongTerm30C-initial-1-Impurity1\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_73d9d304-a0b8-31b6-1165-346563b9305e\">ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</a></p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#Substance_a3fdc23b-6c16-2e65-481e-3fc895b37b87\">Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-batch-analysis-pq-ex1-prod.html#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\">Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</a></p><p><b>value</b>: 0.1 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm30C-initial-1-Impurity2</b><a name=\"LongTerm30C-initial-1-Impurity2\"> </a><a name=\"hcLongTerm30C-initial-1-Impurity2\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_73d9d304-a0b8-31b6-1165-346563b9305e\">ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</a></p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#Substance_a3fdc23b-6c16-2e65-481e-3fc895b37b87\">Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-batch-analysis-pq-ex1-prod.html#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\">Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</a></p><p><b>value</b>: 0.2 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 2 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm30C-initial-1-ImpurityUnspecified</b><a name=\"LongTerm30C-initial-1-ImpurityUnspecified\"> </a><a name=\"hcLongTerm30C-initial-1-ImpurityUnspecified\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_73d9d304-a0b8-31b6-1165-346563b9305e\">ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</a></p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#Substance_a3fdc23b-6c16-2e65-481e-3fc895b37b87\">Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-batch-analysis-pq-ex1-prod.html#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\">Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</a></p><p><b>value</b>: &lt;0.05 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Any Unspecified Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm30C-initial-1-ImpurityTotal</b><a name=\"LongTerm30C-initial-1-ImpurityTotal\"> </a><a name=\"hcLongTerm30C-initial-1-ImpurityTotal\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_73d9d304-a0b8-31b6-1165-346563b9305e\">ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</a></p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#Substance_a3fdc23b-6c16-2e65-481e-3fc895b37b87\">Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-batch-analysis-pq-ex1-prod.html#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\">Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</a></p><p><b>value</b>: 0.8 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Total Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm30C-initial-1-Assay</b><a name=\"LongTerm30C-initial-1-Assay\"> </a><a name=\"hcLongTerm30C-initial-1-Assay\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#ObservationDefinition_7943795a-2abe-666f-545f-133e23b97119\">ObservationDefinition/7943795a-2abe-666f-545f-133e23b97119</a></p><p><b>status</b>: final</p><p><b>code</b>: Assay <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#ASSAY)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#Substance_a3fdc23b-6c16-2e65-481e-3fc895b37b87\">Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-batch-analysis-pq-ex1-prod.html#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\">Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</a></p><p><b>value</b>: 0.15 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm30C-initial-1-Identification</b><a name=\"LongTerm30C-initial-1-Identification\"> </a><a name=\"hcLongTerm30C-initial-1-Identification\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#ObservationDefinition_6b96124b-1a44-0b6b-6783-d6c49360230b\">ObservationDefinition/6b96124b-1a44-0b6b-6783-d6c49360230b</a></p><p><b>status</b>: final</p><p><b>code</b>: Identification <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IDT)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#Substance_a3fdc23b-6c16-2e65-481e-3fc895b37b87\">Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-batch-analysis-pq-ex1-prod.html#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\">Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</a></p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote></div>"
            },
            "contained" : [
              {
                "resourceType" : "Observation",
                "id" : "LongTerm30C-initial-1-Description",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/559ffdc3-349b-a4a3-a651-ce2715f08d69"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Description
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "DESC",
                      "display" : "Description"
                    }
                  ],
                  "text" : "Description"
                },
                "subject" : {
                  "reference" : "Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Substance/actual-batch-substance
                  {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
                  }
                ],
                "valueCodeableConcept" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
                {
                  "text" : "Complies"
                }
              },
              {
                "resourceType" : "Observation",
                "id" : "LongTerm30C-initial-1-Impurity1",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Impurities
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "DGP",
                      "display" : "Degradation Products"
                    }
                  ],
                  "text" : "Degradation Products"
                },
                "subject" : {
                  "reference" : "Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Substance/actual-batch-substance
                  {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
                  }
                ],
                "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
                {
                  "value" : 0.1,
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                },
                "component" : [
                  {
                    "code" : {
                      "coding" : [
                        {
                          "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                          "code" : "IMP",
                          "display" : "Impurity"
                        }
                      ]
                    },
                    "valueCodeableConcept" : {
                      "text" : "Impurity"
                    }
                  }
                ]
              },
              //  could have the code of an impurity substance, or could have an extension to point to it as a resource
              {
                "resourceType" : "Observation",
                "id" : "LongTerm30C-initial-1-Impurity2",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Impurities
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Impurities",
                      "display" : "Impurities"
                    }
                  ],
                  "text" : "Impurities"
                },
                "subject" : {
                  "reference" : "Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Substance/actual-batch-substance
                  {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
                  }
                ],
                "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
                {
                  "value" : 0.2,
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                },
                "component" : [
                  {
                    "code" : {
                      "coding" : [
                        {
                          "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                          "code" : "IMP",
                          "display" : "Impurity"
                        }
                      ]
                    },
                    "valueCodeableConcept" : {
                      "text" : "Impurity 2"
                    }
                  }
                ]
              },
              {
                "resourceType" : "Observation",
                "id" : "LongTerm30C-initial-1-ImpurityUnspecified",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Impurities
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Impurities",
                      "display" : "Impurities"
                    }
                  ],
                  "text" : "Impurities"
                },
                "subject" : {
                  "reference" : "Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Substance/actual-batch-substance
                  {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
                  }
                ],
                "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
                {
                  "value" : 0.05,
                  "comparator" : "<",
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                },
                "component" : [
                  {
                    "code" : {
                      "coding" : [
                        {
                          "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                          "code" : "IMP",
                          "display" : "Impurity"
                        }
                      ]
                    },
                    "valueCodeableConcept" : {
                      "text" : "Any Unspecified Impurity"
                    }
                  }
                ]
              },
              {
                "resourceType" : "Observation",
                "id" : "LongTerm30C-initial-1-ImpurityTotal",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Impurities
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Impurities",
                      "display" : "Impurities"
                    }
                  ],
                  "text" : "Impurities"
                },
                "subject" : {
                  "reference" : "Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Substance/actual-batch-substance
                  {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
                  }
                ],
                "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
                {
                  "value" : 0.8,
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                },
                "component" : [
                  {
                    "code" : {
                      "coding" : [
                        {
                          "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                          "code" : "IMP",
                          "display" : "Impurity"
                        }
                      ]
                    },
                    "valueCodeableConcept" : {
                      "text" : "Total Impurities"
                    }
                  }
                ]
              },
              {
                "resourceType" : "Observation",
                "id" : "LongTerm30C-initial-1-Assay",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/7943795a-2abe-666f-545f-133e23b97119"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Assay
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "ASSAY",
                      "display" : "Assay"
                    }
                  ]
                },
                "subject" : {
                  "reference" : "Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Substance/actual-batch-substance
                  {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
                  }
                ],
                "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
                {
                  "value" : 0.15,
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                }
              },
              {
                "resourceType" : "Observation",
                "id" : "LongTerm30C-initial-1-Identification",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/6b96124b-1a44-0b6b-6783-d6c49360230b"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Identification
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "IDT",
                      "display" : "Identification"
                    }
                  ],
                  "text" : "Identification"
                },
                "subject" : {
                  "reference" : "Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Substance/actual-batch-substance
                  {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
                  }
                ],
                "valueCodeableConcept" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
                {
                  "text" : "Complies"
                }
              }
            ],
            "extension" : [
              {
                "url" : "http://hl7.org/fhir/StructureDefinition/workflow-triggeredBy",
                "valueReference" : {
                  "reference" : "ActivityDefinition/10d7b693-7a0e-2f71-9a10-642e5a0a5d42"
                }
              }
            ],
            "status" : "final",
            "code" : // ActivityDefinition/activityLongTerm30XY-Initial
            {
              "text" : "Test Components - Long-term 25C etc - Initial (XYZ)"
            },
            "subject" : {
              "reference" : "Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/actual-batch-substance
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "specimen" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "reference" : "Specimen/6a5354bf-602c-99f1-324b-0bb5f7e06cd5"
            },
            "hasMember" : [
              // Specimen/stabilityInitial-1
              {
                "reference" : "#LongTerm30C-initial-1-Description"
              },
              {
                "reference" : "#LongTerm30C-initial-1-Assay"
              },
              {
                "reference" : "#LongTerm30C-initial-1-Impurity1"
              },
              {
                "reference" : "#LongTerm30C-initial-1-Impurity2"
              },
              {
                "reference" : "#LongTerm30C-initial-1-ImpurityUnspecified"
              },
              {
                "reference" : "#LongTerm30C-initial-1-ImpurityTotal"
              },
              {
                "reference" : "#LongTerm30C-initial-1-Identification"
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:3b550915-4467-83d3-340f-9bd6d2857191",
          "resource" : {
            "resourceType" : "Specimen",
            "id" : "3b550915-4467-83d3-340f-9bd6d2857191",
            "text" : // stabilityInitial-2
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Specimen_3b550915-4467-83d3-340f-9bd6d2857191\"> </a><p><b>Generated Narrative: Specimen</b><a name=\"3b550915-4467-83d3-340f-9bd6d2857191\"> </a><a name=\"hc3b550915-4467-83d3-340f-9bd6d2857191\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Specimen &quot;3b550915-4467-83d3-340f-9bd6d2857191&quot; </p></div><h3>Collections</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Collected[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>2020-06</td></tr></table><blockquote><p><b>processing</b></p><p><b>description</b>: No storage</p></blockquote><blockquote><p><b>processing</b></p><p><b>description</b>: 25°C/60% RH</p></blockquote></div>"
            },
            "collection" : //  when sample first taken, before the timed periods start
            {
              "collectedDateTime" : "2020-06"
            },
            "processing" : [
              {
                "description" : "No storage"
              },
              {
                "description" : "25°C/60% RH"
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:930c7f69-2546-7148-2069-b3be3a755edf",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "930c7f69-2546-7148-2069-b3be3a755edf",
            "text" : // LongTerm30C-Initial-2
            {
              "status" : "extensions",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_930c7f69-2546-7148-2069-b3be3a755edf\"> </a><p><b>Generated Narrative: Observation</b><a name=\"930c7f69-2546-7148-2069-b3be3a755edf\"> </a><a name=\"hc930c7f69-2546-7148-2069-b3be3a755edf\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;930c7f69-2546-7148-2069-b3be3a755edf&quot; </p></div><p><b>Triggered by</b>: See on this page: ActivityDefinition/10d7b693-7a0e-2f71-9a10-642e5a0a5d42</p><p><b>status</b>: final</p><p><b>code</b>: Test Components - Long-term 25C etc - Initial (XYZ) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>subject</b>: See on this page: Substance/cbcecab6-374c-396f-29be-877da7285e8d</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>specimen</b>: See on this page: Specimen/3b550915-4467-83d3-340f-9bd6d2857191</p><p><b>hasMember</b>: </p><ul><li><a name=\"hcLongTerm30C-initial-2-Description\"> </a></li><li><a name=\"hcLongTerm30C-initial-2-Assay\"> </a></li><li><a name=\"hcLongTerm30C-initial-2-Degradation-imp1\"> </a></li><li><a name=\"hcLongTerm30C-initial-2-Degradation-imp2\"> </a></li><li><a name=\"hcLongTerm30C-initial-2-Degradation-impUnspecified\"> </a></li><li><a name=\"hcLongTerm30C-initial-2-Degradation-impTotal\"> </a></li><li><a name=\"hcLongTerm30C-initial-2-Identification\"> </a></li></ul><blockquote><p/><p><a name=\"LongTerm30C-initial-2-Description\"> </a></p><p><a name=\"hcLongTerm30C-initial-2-Description\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/559ffdc3-349b-a4a3-a651-ce2715f08d69</p><p><b>status</b>: final</p><p><b>code</b>: Description <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DESC)</span></p><p><b>subject</b>: See on this page: Substance/cbcecab6-374c-396f-29be-877da7285e8d</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><blockquote><p/><p><a name=\"LongTerm30C-initial-2-Assay\"> </a></p><p><a name=\"hcLongTerm30C-initial-2-Assay\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/7943795a-2abe-666f-545f-133e23b97119</p><p><b>status</b>: final</p><p><b>code</b>: Assay <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#ASSAY)</span></p><p><b>subject</b>: See on this page: Substance/cbcecab6-374c-396f-29be-877da7285e8d</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.152 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p></blockquote><blockquote><p/><p><a name=\"LongTerm30C-initial-2-Degradation-imp1\"> </a></p><p><a name=\"hcLongTerm30C-initial-2-Degradation-imp1\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Substance/cbcecab6-374c-396f-29be-877da7285e8d</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.12 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p/><p><a name=\"LongTerm30C-initial-2-Degradation-imp2\"> </a></p><p><a name=\"hcLongTerm30C-initial-2-Degradation-imp2\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: See on this page: Substance/cbcecab6-374c-396f-29be-877da7285e8d</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.22 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 2 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p/><p><a name=\"LongTerm30C-initial-2-Degradation-impUnspecified\"> </a></p><p><a name=\"hcLongTerm30C-initial-2-Degradation-impUnspecified\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: See on this page: Substance/cbcecab6-374c-396f-29be-877da7285e8d</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: &lt;0.052 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Any Unspecified Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p/><p><a name=\"LongTerm30C-initial-2-Degradation-impTotal\"> </a></p><p><a name=\"hcLongTerm30C-initial-2-Degradation-impTotal\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: See on this page: Substance/cbcecab6-374c-396f-29be-877da7285e8d</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.82 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Total Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p/><p><a name=\"LongTerm30C-initial-2-Identification\"> </a></p><p><a name=\"hcLongTerm30C-initial-2-Identification\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/6b96124b-1a44-0b6b-6783-d6c49360230b</p><p><b>status</b>: final</p><p><b>code</b>: Identification <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IDT)</span></p><p><b>subject</b>: See on this page: Substance/cbcecab6-374c-396f-29be-877da7285e8d</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: Does not comply <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm30C-initial-2-Description</b><a name=\"LongTerm30C-initial-2-Description\"> </a><a name=\"hcLongTerm30C-initial-2-Description\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#ObservationDefinition_559ffdc3-349b-a4a3-a651-ce2715f08d69\">ObservationDefinition/559ffdc3-349b-a4a3-a651-ce2715f08d69</a></p><p><b>status</b>: final</p><p><b>code</b>: Description <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DESC)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#Substance_cbcecab6-374c-396f-29be-877da7285e8d\">Substance/cbcecab6-374c-396f-29be-877da7285e8d</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-batch-analysis-pq-ex1-prod.html#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\">Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</a></p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm30C-initial-2-Degradation-imp1</b><a name=\"LongTerm30C-initial-2-Degradation-imp1\"> </a><a name=\"hcLongTerm30C-initial-2-Degradation-imp1\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_73d9d304-a0b8-31b6-1165-346563b9305e\">ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</a></p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#Substance_cbcecab6-374c-396f-29be-877da7285e8d\">Substance/cbcecab6-374c-396f-29be-877da7285e8d</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-batch-analysis-pq-ex1-prod.html#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\">Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</a></p><p><b>value</b>: 0.12 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm30C-initial-2-Degradation-imp2</b><a name=\"LongTerm30C-initial-2-Degradation-imp2\"> </a><a name=\"hcLongTerm30C-initial-2-Degradation-imp2\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_73d9d304-a0b8-31b6-1165-346563b9305e\">ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</a></p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#Substance_cbcecab6-374c-396f-29be-877da7285e8d\">Substance/cbcecab6-374c-396f-29be-877da7285e8d</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-batch-analysis-pq-ex1-prod.html#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\">Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</a></p><p><b>value</b>: 0.22 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 2 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm30C-initial-2-Degradation-impUnspecified</b><a name=\"LongTerm30C-initial-2-Degradation-impUnspecified\"> </a><a name=\"hcLongTerm30C-initial-2-Degradation-impUnspecified\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_73d9d304-a0b8-31b6-1165-346563b9305e\">ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</a></p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#Substance_cbcecab6-374c-396f-29be-877da7285e8d\">Substance/cbcecab6-374c-396f-29be-877da7285e8d</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-batch-analysis-pq-ex1-prod.html#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\">Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</a></p><p><b>value</b>: &lt;0.052 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Any Unspecified Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm30C-initial-2-Degradation-impTotal</b><a name=\"LongTerm30C-initial-2-Degradation-impTotal\"> </a><a name=\"hcLongTerm30C-initial-2-Degradation-impTotal\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_73d9d304-a0b8-31b6-1165-346563b9305e\">ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</a></p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#Substance_cbcecab6-374c-396f-29be-877da7285e8d\">Substance/cbcecab6-374c-396f-29be-877da7285e8d</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-batch-analysis-pq-ex1-prod.html#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\">Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</a></p><p><b>value</b>: 0.82 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Total Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm30C-initial-2-Assay</b><a name=\"LongTerm30C-initial-2-Assay\"> </a><a name=\"hcLongTerm30C-initial-2-Assay\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#ObservationDefinition_7943795a-2abe-666f-545f-133e23b97119\">ObservationDefinition/7943795a-2abe-666f-545f-133e23b97119</a></p><p><b>status</b>: final</p><p><b>code</b>: Assay <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#ASSAY)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#Substance_cbcecab6-374c-396f-29be-877da7285e8d\">Substance/cbcecab6-374c-396f-29be-877da7285e8d</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-batch-analysis-pq-ex1-prod.html#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\">Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</a></p><p><b>value</b>: 0.152 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm30C-initial-2-Identification</b><a name=\"LongTerm30C-initial-2-Identification\"> </a><a name=\"hcLongTerm30C-initial-2-Identification\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#ObservationDefinition_6b96124b-1a44-0b6b-6783-d6c49360230b\">ObservationDefinition/6b96124b-1a44-0b6b-6783-d6c49360230b</a></p><p><b>status</b>: final</p><p><b>code</b>: Identification <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IDT)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#Substance_cbcecab6-374c-396f-29be-877da7285e8d\">Substance/cbcecab6-374c-396f-29be-877da7285e8d</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-batch-analysis-pq-ex1-prod.html#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\">Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</a></p><p><b>value</b>: Does not comply <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote></div>"
            },
            "contained" : [
              {
                "resourceType" : "Observation",
                "id" : "LongTerm30C-initial-2-Description",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/559ffdc3-349b-a4a3-a651-ce2715f08d69"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Description
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "DESC",
                      "display" : "Description"
                    }
                  ],
                  "text" : "Description"
                },
                "subject" : {
                  "reference" : "Substance/cbcecab6-374c-396f-29be-877da7285e8d"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Substance/actual-batch-substance-2
                  {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
                  }
                ],
                "valueCodeableConcept" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
                {
                  "text" : "Complies"
                }
              },
              {
                "resourceType" : "Observation",
                "id" : "LongTerm30C-initial-2-Degradation-imp1",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Impurities
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "DGP",
                      "display" : "Degradation Products"
                    }
                  ],
                  "text" : "Degradation Products"
                },
                "subject" : {
                  "reference" : "Substance/cbcecab6-374c-396f-29be-877da7285e8d"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Substance/actual-batch-substance-2
                  {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
                  }
                ],
                "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
                {
                  "value" : 0.12,
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                },
                "component" : [
                  {
                    "code" : {
                      "coding" : [
                        {
                          "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                          "code" : "IMP",
                          "display" : "Impurity"
                        }
                      ]
                    },
                    "valueCodeableConcept" : {
                      "text" : "Impurity"
                    }
                  }
                ]
              },
              //  could have the code of an impurity substance, or could have an extension to point to it as a resource
              {
                "resourceType" : "Observation",
                "id" : "LongTerm30C-initial-2-Degradation-imp2",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Impurities
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Impurities",
                      "display" : "Impurities"
                    }
                  ],
                  "text" : "Impurities"
                },
                "subject" : {
                  "reference" : "Substance/cbcecab6-374c-396f-29be-877da7285e8d"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Substance/actual-batch-substance-2
                  {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
                  }
                ],
                "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
                {
                  "value" : 0.22,
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                },
                "component" : [
                  {
                    "code" : {
                      "coding" : [
                        {
                          "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                          "code" : "IMP",
                          "display" : "Impurity"
                        }
                      ]
                    },
                    "valueCodeableConcept" : {
                      "text" : "Impurity 2"
                    }
                  }
                ]
              },
              {
                "resourceType" : "Observation",
                "id" : "LongTerm30C-initial-2-Degradation-impUnspecified",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Impurities
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Impurities",
                      "display" : "Impurities"
                    }
                  ],
                  "text" : "Impurities"
                },
                "subject" : {
                  "reference" : "Substance/cbcecab6-374c-396f-29be-877da7285e8d"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Substance/actual-batch-substance-2
                  {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
                  }
                ],
                "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
                {
                  "value" : 0.052,
                  "comparator" : "<",
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                },
                "component" : [
                  {
                    "code" : {
                      "coding" : [
                        {
                          "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                          "code" : "IMP",
                          "display" : "Impurity"
                        }
                      ]
                    },
                    "valueCodeableConcept" : {
                      "text" : "Any Unspecified Impurity"
                    }
                  }
                ]
              },
              {
                "resourceType" : "Observation",
                "id" : "LongTerm30C-initial-2-Degradation-impTotal",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Impurities
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Impurities",
                      "display" : "Impurities"
                    }
                  ],
                  "text" : "Impurities"
                },
                "subject" : {
                  "reference" : "Substance/cbcecab6-374c-396f-29be-877da7285e8d"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Substance/actual-batch-substance-2
                  {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
                  }
                ],
                "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
                {
                  "value" : 0.82,
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                },
                "component" : [
                  {
                    "code" : {
                      "coding" : [
                        {
                          "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                          "code" : "IMP",
                          "display" : "Impurity"
                        }
                      ]
                    },
                    "valueCodeableConcept" : {
                      "text" : "Total Impurities"
                    }
                  }
                ]
              },
              {
                "resourceType" : "Observation",
                "id" : "LongTerm30C-initial-2-Assay",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/7943795a-2abe-666f-545f-133e23b97119"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Assay
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "ASSAY",
                      "display" : "Assay"
                    }
                  ]
                },
                "subject" : {
                  "reference" : "Substance/cbcecab6-374c-396f-29be-877da7285e8d"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Substance/actual-batch-substance-2
                  {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
                  }
                ],
                "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
                {
                  "value" : 0.152,
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                }
              },
              {
                "resourceType" : "Observation",
                "id" : "LongTerm30C-initial-2-Identification",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/6b96124b-1a44-0b6b-6783-d6c49360230b"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Identification
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "IDT",
                      "display" : "Identification"
                    }
                  ],
                  "text" : "Identification"
                },
                "subject" : {
                  "reference" : "Substance/cbcecab6-374c-396f-29be-877da7285e8d"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Substance/actual-batch-substance-2
                  {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
                  }
                ],
                "valueCodeableConcept" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
                {
                  "text" : "Does not comply"
                }
              }
            ],
            "extension" : [
              {
                "url" : "http://hl7.org/fhir/StructureDefinition/workflow-triggeredBy",
                "valueReference" : {
                  "reference" : "ActivityDefinition/10d7b693-7a0e-2f71-9a10-642e5a0a5d42"
                }
              }
            ],
            "status" : "final",
            "code" : // ActivityDefinition/activityLongTerm30XY-Initial
            {
              "text" : "Test Components - Long-term 25C etc - Initial (XYZ)"
            },
            "subject" : {
              "reference" : "Substance/cbcecab6-374c-396f-29be-877da7285e8d"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/actual-batch-substance-2
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "specimen" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "reference" : "Specimen/3b550915-4467-83d3-340f-9bd6d2857191"
            },
            "hasMember" : [
              // Specimen/stabilityInitial-2
              {
                "reference" : "#LongTerm30C-initial-2-Description"
              },
              {
                "reference" : "#LongTerm30C-initial-2-Assay"
              },
              {
                "reference" : "#LongTerm30C-initial-2-Degradation-imp1"
              },
              {
                "reference" : "#LongTerm30C-initial-2-Degradation-imp2"
              },
              {
                "reference" : "#LongTerm30C-initial-2-Degradation-impUnspecified"
              },
              {
                "reference" : "#LongTerm30C-initial-2-Degradation-impTotal"
              },
              {
                "reference" : "#LongTerm30C-initial-2-Identification"
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:b1726ce3-8bb5-403e-2e9b-f5d79cc716f9",
          "resource" : {
            "resourceType" : "Specimen",
            "id" : "b1726ce3-8bb5-403e-2e9b-f5d79cc716f9",
            "text" : // stabilityInitial-3
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Specimen_b1726ce3-8bb5-403e-2e9b-f5d79cc716f9\"> </a><p><b>Generated Narrative: Specimen</b><a name=\"b1726ce3-8bb5-403e-2e9b-f5d79cc716f9\"> </a><a name=\"hcb1726ce3-8bb5-403e-2e9b-f5d79cc716f9\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Specimen &quot;b1726ce3-8bb5-403e-2e9b-f5d79cc716f9&quot; </p></div><h3>Collections</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Collected[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>2020-06</td></tr></table><blockquote><p><b>processing</b></p><p><b>description</b>: No storage</p></blockquote><blockquote><p><b>processing</b></p><p><b>description</b>: 25°C/60% RH</p></blockquote></div>"
            },
            "collection" : //  when sample first taken, before the timed periods start
            {
              "collectedDateTime" : "2020-06"
            },
            "processing" : [
              {
                "description" : "No storage"
              },
              {
                "description" : "25°C/60% RH"
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:8070745c-30c4-a52e-41fd-600a913578d4",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "8070745c-30c4-a52e-41fd-600a913578d4",
            "text" : // LongTerm30C-Initial-3
            {
              "status" : "extensions",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_8070745c-30c4-a52e-41fd-600a913578d4\"> </a><p><b>Generated Narrative: Observation</b><a name=\"8070745c-30c4-a52e-41fd-600a913578d4\"> </a><a name=\"hc8070745c-30c4-a52e-41fd-600a913578d4\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;8070745c-30c4-a52e-41fd-600a913578d4&quot; </p></div><p><b>Triggered by</b>: See on this page: ActivityDefinition/10d7b693-7a0e-2f71-9a10-642e5a0a5d42</p><p><b>status</b>: final</p><p><b>code</b>: Test Components - Long-term 25C etc - Initial (XYZ) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>subject</b>: See on this page: Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>specimen</b>: See on this page: Specimen/b1726ce3-8bb5-403e-2e9b-f5d79cc716f9</p><p><b>hasMember</b>: </p><ul><li><a name=\"hcLongTerm30C-initial-3-Description\"> </a></li><li><a name=\"hcLongTerm30C-initial-3-Assay\"> </a></li><li><a name=\"hcLongTerm30C-initial-3-Degradation-imp1\"> </a></li><li><a name=\"hcLongTerm30C-initial-3-Degradation-imp2\"> </a></li><li><a name=\"hcLongTerm30C-initial-3-Degradation-impUnspecified\"> </a></li><li><a name=\"hcLongTerm30C-initial-3-Degradation-impTotal\"> </a></li><li><a name=\"hcLongTerm30C-initial-3-Identification\"> </a></li></ul><blockquote><p/><p><a name=\"LongTerm30C-initial-3-Description\"> </a></p><p><a name=\"hcLongTerm30C-initial-3-Description\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/559ffdc3-349b-a4a3-a651-ce2715f08d69</p><p><b>status</b>: final</p><p><b>code</b>: Description <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DESC)</span></p><p><b>subject</b>: See on this page: Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><blockquote><p/><p><a name=\"LongTerm30C-initial-3-Assay\"> </a></p><p><a name=\"hcLongTerm30C-initial-3-Assay\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/7943795a-2abe-666f-545f-133e23b97119</p><p><b>status</b>: final</p><p><b>code</b>: Assay <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#ASSAY)</span></p><p><b>subject</b>: See on this page: Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.152 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p></blockquote><blockquote><p/><p><a name=\"LongTerm30C-initial-3-Degradation-imp1\"> </a></p><p><a name=\"hcLongTerm30C-initial-3-Degradation-imp1\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.12 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p/><p><a name=\"LongTerm30C-initial-3-Degradation-imp2\"> </a></p><p><a name=\"hcLongTerm30C-initial-3-Degradation-imp2\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: See on this page: Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.22 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 2 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p/><p><a name=\"LongTerm30C-initial-3-Degradation-impUnspecified\"> </a></p><p><a name=\"hcLongTerm30C-initial-3-Degradation-impUnspecified\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: See on this page: Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: &lt;0.052 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Any Unspecified Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p/><p><a name=\"LongTerm30C-initial-3-Degradation-impTotal\"> </a></p><p><a name=\"hcLongTerm30C-initial-3-Degradation-impTotal\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: See on this page: Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.82 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Total Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p/><p><a name=\"LongTerm30C-initial-3-Identification\"> </a></p><p><a name=\"hcLongTerm30C-initial-3-Identification\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/6b96124b-1a44-0b6b-6783-d6c49360230b</p><p><b>status</b>: final</p><p><b>code</b>: Identification <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IDT)</span></p><p><b>subject</b>: See on this page: Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: Does not comply <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm30C-initial-3-Description</b><a name=\"LongTerm30C-initial-3-Description\"> </a><a name=\"hcLongTerm30C-initial-3-Description\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#ObservationDefinition_559ffdc3-349b-a4a3-a651-ce2715f08d69\">ObservationDefinition/559ffdc3-349b-a4a3-a651-ce2715f08d69</a></p><p><b>status</b>: final</p><p><b>code</b>: Description <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DESC)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#Substance_ae1f3b4c-4f14-1460-6903-7260959ea2cd\">Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-batch-analysis-pq-ex1-prod.html#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\">Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</a></p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm30C-initial-3-Degradation-imp1</b><a name=\"LongTerm30C-initial-3-Degradation-imp1\"> </a><a name=\"hcLongTerm30C-initial-3-Degradation-imp1\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_73d9d304-a0b8-31b6-1165-346563b9305e\">ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</a></p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#Substance_ae1f3b4c-4f14-1460-6903-7260959ea2cd\">Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-batch-analysis-pq-ex1-prod.html#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\">Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</a></p><p><b>value</b>: 0.12 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm30C-initial-3-Degradation-imp2</b><a name=\"LongTerm30C-initial-3-Degradation-imp2\"> </a><a name=\"hcLongTerm30C-initial-3-Degradation-imp2\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_73d9d304-a0b8-31b6-1165-346563b9305e\">ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</a></p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#Substance_ae1f3b4c-4f14-1460-6903-7260959ea2cd\">Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-batch-analysis-pq-ex1-prod.html#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\">Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</a></p><p><b>value</b>: 0.22 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 2 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm30C-initial-3-Degradation-impUnspecified</b><a name=\"LongTerm30C-initial-3-Degradation-impUnspecified\"> </a><a name=\"hcLongTerm30C-initial-3-Degradation-impUnspecified\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_73d9d304-a0b8-31b6-1165-346563b9305e\">ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</a></p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#Substance_ae1f3b4c-4f14-1460-6903-7260959ea2cd\">Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-batch-analysis-pq-ex1-prod.html#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\">Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</a></p><p><b>value</b>: &lt;0.052 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Any Unspecified Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm30C-initial-3-Degradation-impTotal</b><a name=\"LongTerm30C-initial-3-Degradation-impTotal\"> </a><a name=\"hcLongTerm30C-initial-3-Degradation-impTotal\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_73d9d304-a0b8-31b6-1165-346563b9305e\">ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</a></p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#Substance_ae1f3b4c-4f14-1460-6903-7260959ea2cd\">Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-batch-analysis-pq-ex1-prod.html#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\">Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</a></p><p><b>value</b>: 0.82 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Total Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm30C-initial-3-Assay</b><a name=\"LongTerm30C-initial-3-Assay\"> </a><a name=\"hcLongTerm30C-initial-3-Assay\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#ObservationDefinition_7943795a-2abe-666f-545f-133e23b97119\">ObservationDefinition/7943795a-2abe-666f-545f-133e23b97119</a></p><p><b>status</b>: final</p><p><b>code</b>: Assay <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#ASSAY)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#Substance_ae1f3b4c-4f14-1460-6903-7260959ea2cd\">Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-batch-analysis-pq-ex1-prod.html#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\">Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</a></p><p><b>value</b>: 0.152 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm30C-initial-3-Identification</b><a name=\"LongTerm30C-initial-3-Identification\"> </a><a name=\"hcLongTerm30C-initial-3-Identification\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#ObservationDefinition_6b96124b-1a44-0b6b-6783-d6c49360230b\">ObservationDefinition/6b96124b-1a44-0b6b-6783-d6c49360230b</a></p><p><b>status</b>: final</p><p><b>code</b>: Identification <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IDT)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#Substance_ae1f3b4c-4f14-1460-6903-7260959ea2cd\">Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-batch-analysis-pq-ex1-prod.html#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\">Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</a></p><p><b>value</b>: Does not comply <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote></div>"
            },
            "contained" : [
              {
                "resourceType" : "Observation",
                "id" : "LongTerm30C-initial-3-Description",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/559ffdc3-349b-a4a3-a651-ce2715f08d69"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Description
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "DESC",
                      "display" : "Description"
                    }
                  ],
                  "text" : "Description"
                },
                "subject" : {
                  "reference" : "Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Substance/actual-batch-substance-3
                  {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
                  }
                ],
                "valueCodeableConcept" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
                {
                  "text" : "Complies"
                }
              },
              {
                "resourceType" : "Observation",
                "id" : "LongTerm30C-initial-3-Degradation-imp1",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Impurities
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "DGP",
                      "display" : "Degradation Products"
                    }
                  ],
                  "text" : "Degradation Products"
                },
                "subject" : {
                  "reference" : "Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Substance/actual-batch-substance-3
                  {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
                  }
                ],
                "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
                {
                  "value" : 0.12,
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                },
                "component" : [
                  {
                    "code" : {
                      "coding" : [
                        {
                          "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                          "code" : "IMP",
                          "display" : "Impurity"
                        }
                      ]
                    },
                    "valueCodeableConcept" : {
                      "text" : "Impurity"
                    }
                  }
                ]
              },
              //  could have the code of an impurity substance, or could have an extension to point to it as a resource
              {
                "resourceType" : "Observation",
                "id" : "LongTerm30C-initial-3-Degradation-imp2",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Impurities
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Impurities",
                      "display" : "Impurities"
                    }
                  ],
                  "text" : "Impurities"
                },
                "subject" : {
                  "reference" : "Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Substance/actual-batch-substance-3
                  {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
                  }
                ],
                "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
                {
                  "value" : 0.22,
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                },
                "component" : [
                  {
                    "code" : {
                      "coding" : [
                        {
                          "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                          "code" : "IMP",
                          "display" : "Impurity"
                        }
                      ]
                    },
                    "valueCodeableConcept" : {
                      "text" : "Impurity 2"
                    }
                  }
                ]
              },
              {
                "resourceType" : "Observation",
                "id" : "LongTerm30C-initial-3-Degradation-impUnspecified",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Impurities
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Impurities",
                      "display" : "Impurities"
                    }
                  ],
                  "text" : "Impurities"
                },
                "subject" : {
                  "reference" : "Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Substance/actual-batch-substance-3
                  {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
                  }
                ],
                "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
                {
                  "value" : 0.052,
                  "comparator" : "<",
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                },
                "component" : [
                  {
                    "code" : {
                      "coding" : [
                        {
                          "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                          "code" : "IMP",
                          "display" : "Impurity"
                        }
                      ]
                    },
                    "valueCodeableConcept" : {
                      "text" : "Any Unspecified Impurity"
                    }
                  }
                ]
              },
              {
                "resourceType" : "Observation",
                "id" : "LongTerm30C-initial-3-Degradation-impTotal",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Impurities
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Impurities",
                      "display" : "Impurities"
                    }
                  ],
                  "text" : "Impurities"
                },
                "subject" : {
                  "reference" : "Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Substance/actual-batch-substance-3
                  {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
                  }
                ],
                "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
                {
                  "value" : 0.82,
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                },
                "component" : [
                  {
                    "code" : {
                      "coding" : [
                        {
                          "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                          "code" : "IMP",
                          "display" : "Impurity"
                        }
                      ]
                    },
                    "valueCodeableConcept" : {
                      "text" : "Total Impurities"
                    }
                  }
                ]
              },
              {
                "resourceType" : "Observation",
                "id" : "LongTerm30C-initial-3-Assay",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/7943795a-2abe-666f-545f-133e23b97119"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Assay
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "ASSAY",
                      "display" : "Assay"
                    }
                  ]
                },
                "subject" : {
                  "reference" : "Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Substance/actual-batch-substance-3
                  {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
                  }
                ],
                "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
                {
                  "value" : 0.152,
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                }
              },
              {
                "resourceType" : "Observation",
                "id" : "LongTerm30C-initial-3-Identification",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/6b96124b-1a44-0b6b-6783-d6c49360230b"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Identification
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "IDT",
                      "display" : "Identification"
                    }
                  ],
                  "text" : "Identification"
                },
                "subject" : {
                  "reference" : "Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Substance/actual-batch-substance-3
                  {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
                  }
                ],
                "valueCodeableConcept" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
                {
                  "text" : "Does not comply"
                }
              }
            ],
            "extension" : [
              {
                "url" : "http://hl7.org/fhir/StructureDefinition/workflow-triggeredBy",
                "valueReference" : {
                  "reference" : "ActivityDefinition/10d7b693-7a0e-2f71-9a10-642e5a0a5d42"
                }
              }
            ],
            "status" : "final",
            "code" : // ActivityDefinition/activityLongTerm30XY-Initial
            {
              "text" : "Test Components - Long-term 25C etc - Initial (XYZ)"
            },
            "subject" : {
              "reference" : "Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/actual-batch-substance-3
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "specimen" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "reference" : "Specimen/b1726ce3-8bb5-403e-2e9b-f5d79cc716f9"
            },
            "hasMember" : [
              // Specimen/stabilityInitial-3
              {
                "reference" : "#LongTerm30C-initial-3-Description"
              },
              {
                "reference" : "#LongTerm30C-initial-3-Assay"
              },
              {
                "reference" : "#LongTerm30C-initial-3-Degradation-imp1"
              },
              {
                "reference" : "#LongTerm30C-initial-3-Degradation-imp2"
              },
              {
                "reference" : "#LongTerm30C-initial-3-Degradation-impUnspecified"
              },
              {
                "reference" : "#LongTerm30C-initial-3-Degradation-impTotal"
              },
              {
                "reference" : "#LongTerm30C-initial-3-Identification"
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:7aa5fdea-17d7-29f1-1ed4-5c05eb62285a",
          "resource" : {
            "resourceType" : "Specimen",
            "id" : "7aa5fdea-17d7-29f1-1ed4-5c05eb62285a",
            "text" : // stability18months-1
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Specimen_7aa5fdea-17d7-29f1-1ed4-5c05eb62285a\"> </a><p><b>Generated Narrative: Specimen</b><a name=\"7aa5fdea-17d7-29f1-1ed4-5c05eb62285a\"> </a><a name=\"hc7aa5fdea-17d7-29f1-1ed4-5c05eb62285a\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Specimen &quot;7aa5fdea-17d7-29f1-1ed4-5c05eb62285a&quot; </p></div><h3>Collections</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Collected[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>2020-06</td></tr></table><blockquote><p><b>processing</b></p><p><b>description</b>: Store for 18 months</p><p><b>time</b>: 2020-12 --&gt; 2022-06</p></blockquote><blockquote><p><b>processing</b></p><p><b>description</b>: 30°C/65% RH</p></blockquote></div>"
            },
            "collection" : {
              "collectedDateTime" : "2020-06"
            },
            "processing" : [
              {
                "description" : "Store for 18 months",
                "timePeriod" : {
                  "extension" : [
                    {
                      "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-storage-duration-pq",
                      "valueDuration" : {
                        "value" : 18,
                        "unit" : "month"
                      }
                    }
                  ],
                  "start" : "2020-12",
                  "end" : "2022-06"
                }
              },
              {
                "description" : "30°C/65% RH"
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:872a645f-120e-44c0-62c0-9be05acf543b",
          "resource" : {
            "resourceType" : "Specimen",
            "id" : "872a645f-120e-44c0-62c0-9be05acf543b",
            "text" : // stability18months-2
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Specimen_872a645f-120e-44c0-62c0-9be05acf543b\"> </a><p><b>Generated Narrative: Specimen</b><a name=\"872a645f-120e-44c0-62c0-9be05acf543b\"> </a><a name=\"hc872a645f-120e-44c0-62c0-9be05acf543b\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Specimen &quot;872a645f-120e-44c0-62c0-9be05acf543b&quot; </p></div><h3>Collections</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Collected[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>2020-06</td></tr></table><blockquote><p><b>processing</b></p><p><b>description</b>: Store for 18 months</p><p><b>time</b>: 2020-12 --&gt; 2022-06</p></blockquote><blockquote><p><b>processing</b></p><p><b>description</b>: 30°C/65% RH</p></blockquote></div>"
            },
            "collection" : {
              "collectedDateTime" : "2020-06"
            },
            "processing" : [
              {
                "description" : "Store for 18 months",
                "timePeriod" : {
                  "extension" : [
                    {
                      "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-storage-duration-pq",
                      "valueDuration" : {
                        "value" : 18,
                        "unit" : "month"
                      }
                    }
                  ],
                  "start" : "2020-12",
                  "end" : "2022-06"
                }
              },
              {
                "description" : "30°C/65% RH"
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:7c06a03c-9cf7-2e1b-a236-d60038f1439b",
          "resource" : {
            "resourceType" : "Specimen",
            "id" : "7c06a03c-9cf7-2e1b-a236-d60038f1439b",
            "text" : // stability18months-3
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Specimen_7c06a03c-9cf7-2e1b-a236-d60038f1439b\"> </a><p><b>Generated Narrative: Specimen</b><a name=\"7c06a03c-9cf7-2e1b-a236-d60038f1439b\"> </a><a name=\"hc7c06a03c-9cf7-2e1b-a236-d60038f1439b\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Specimen &quot;7c06a03c-9cf7-2e1b-a236-d60038f1439b&quot; </p></div><h3>Collections</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Collected[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>2020-06</td></tr></table><blockquote><p><b>processing</b></p><p><b>description</b>: Store for 18 months</p><p><b>time</b>: 2020-12 --&gt; 2022-06</p></blockquote><blockquote><p><b>processing</b></p><p><b>description</b>: 30°C/65% RH</p></blockquote></div>"
            },
            "collection" : {
              "collectedDateTime" : "2020-06"
            },
            "processing" : [
              {
                "description" : "Store for 18 months",
                "timePeriod" : {
                  "extension" : [
                    {
                      "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-storage-duration-pq",
                      "valueDuration" : {
                        "value" : 18,
                        "unit" : "month"
                      }
                    }
                  ],
                  "start" : "2020-12",
                  "end" : "2022-06"
                }
              },
              {
                "description" : "30°C/65% RH"
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:f16113fe-27e7-0aa2-6787-9415f5051900",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "f16113fe-27e7-0aa2-6787-9415f5051900",
            "text" : // LongTerm30C-18m
            {
              "status" : "extensions",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_f16113fe-27e7-0aa2-6787-9415f5051900\"> </a><p><b>Generated Narrative: Observation</b><a name=\"f16113fe-27e7-0aa2-6787-9415f5051900\"> </a><a name=\"hcf16113fe-27e7-0aa2-6787-9415f5051900\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;f16113fe-27e7-0aa2-6787-9415f5051900&quot; </p></div><p><b>Triggered by</b>: See on this page: ActivityDefinition/c9b53a46-2f61-7b3f-5780-5f5c79a47f12</p><p><b>status</b>: final</p><p><b>code</b>: Long-term - 30°C/65% RH - 18 months (X) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>subject</b>: See on this page: Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>specimen</b>: See on this page: Specimen/7aa5fdea-17d7-29f1-1ed4-5c05eb62285a</p><p><b>hasMember</b>: </p><ul><li><a name=\"hcLongTerm30C-18m-1-Description\"> </a></li><li><a name=\"hcLongTerm30C-18m-1-Assay\"> </a></li><li><a name=\"hcLongTerm30C-18m-1-Impurity1\"> </a></li><li><a name=\"hcLongTerm30C-18m-1-Impurity2\"> </a></li><li><a name=\"hcLongTerm30C-18m-1-ImpurityUnspecified\"> </a></li><li><a name=\"hcLongTerm30C-18m-1-ImpurityTotal\"> </a></li><li><a name=\"hcLongTerm30C-18m-1-Identification\"> </a></li></ul><blockquote><p/><p><a name=\"LongTerm30C-18m-1-Description\"> </a></p><p><a name=\"hcLongTerm30C-18m-1-Description\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/559ffdc3-349b-a4a3-a651-ce2715f08d69</p><p><b>status</b>: final</p><p><b>code</b>: Description <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DESC)</span></p><p><b>subject</b>: See on this page: Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><blockquote><p/><p><a name=\"LongTerm30C-18m-1-Assay\"> </a></p><p><a name=\"hcLongTerm30C-18m-1-Assay\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/7943795a-2abe-666f-545f-133e23b97119</p><p><b>status</b>: final</p><p><b>code</b>: Assay <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#ASSAY)</span></p><p><b>subject</b>: See on this page: Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.118 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p></blockquote><blockquote><p/><p><a name=\"LongTerm30C-18m-1-Impurity1\"> </a></p><p><a name=\"hcLongTerm30C-18m-1-Impurity1\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.118 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p/><p><a name=\"LongTerm30C-18m-1-Impurity2\"> </a></p><p><a name=\"hcLongTerm30C-18m-1-Impurity2\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: See on this page: Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.218 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 2 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p/><p><a name=\"LongTerm30C-18m-1-ImpurityUnspecified\"> </a></p><p><a name=\"hcLongTerm30C-18m-1-ImpurityUnspecified\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: See on this page: Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: &lt;0.0518 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Any Unspecified Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p/><p><a name=\"LongTerm30C-18m-1-ImpurityTotal\"> </a></p><p><a name=\"hcLongTerm30C-18m-1-ImpurityTotal\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: See on this page: Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.818 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Total Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p/><p><a name=\"LongTerm30C-18m-1-Identification\"> </a></p><p><a name=\"hcLongTerm30C-18m-1-Identification\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/6b96124b-1a44-0b6b-6783-d6c49360230b</p><p><b>status</b>: final</p><p><b>code</b>: Identification <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IDT)</span></p><p><b>subject</b>: See on this page: Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm30C-18m-1-Description</b><a name=\"LongTerm30C-18m-1-Description\"> </a><a name=\"hcLongTerm30C-18m-1-Description\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#ObservationDefinition_559ffdc3-349b-a4a3-a651-ce2715f08d69\">ObservationDefinition/559ffdc3-349b-a4a3-a651-ce2715f08d69</a></p><p><b>status</b>: final</p><p><b>code</b>: Description <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DESC)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#Substance_a3fdc23b-6c16-2e65-481e-3fc895b37b87\">Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-batch-analysis-pq-ex1-prod.html#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\">Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</a></p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm30C-18m-1-Impurity1</b><a name=\"LongTerm30C-18m-1-Impurity1\"> </a><a name=\"hcLongTerm30C-18m-1-Impurity1\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_73d9d304-a0b8-31b6-1165-346563b9305e\">ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</a></p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#Substance_a3fdc23b-6c16-2e65-481e-3fc895b37b87\">Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-batch-analysis-pq-ex1-prod.html#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\">Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</a></p><p><b>value</b>: 0.118 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm30C-18m-1-Impurity2</b><a name=\"LongTerm30C-18m-1-Impurity2\"> </a><a name=\"hcLongTerm30C-18m-1-Impurity2\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_73d9d304-a0b8-31b6-1165-346563b9305e\">ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</a></p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#Substance_a3fdc23b-6c16-2e65-481e-3fc895b37b87\">Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-batch-analysis-pq-ex1-prod.html#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\">Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</a></p><p><b>value</b>: 0.218 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 2 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm30C-18m-1-ImpurityUnspecified</b><a name=\"LongTerm30C-18m-1-ImpurityUnspecified\"> </a><a name=\"hcLongTerm30C-18m-1-ImpurityUnspecified\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_73d9d304-a0b8-31b6-1165-346563b9305e\">ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</a></p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#Substance_a3fdc23b-6c16-2e65-481e-3fc895b37b87\">Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-batch-analysis-pq-ex1-prod.html#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\">Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</a></p><p><b>value</b>: &lt;0.0518 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Any Unspecified Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm30C-18m-1-ImpurityTotal</b><a name=\"LongTerm30C-18m-1-ImpurityTotal\"> </a><a name=\"hcLongTerm30C-18m-1-ImpurityTotal\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_73d9d304-a0b8-31b6-1165-346563b9305e\">ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</a></p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#Substance_a3fdc23b-6c16-2e65-481e-3fc895b37b87\">Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-batch-analysis-pq-ex1-prod.html#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\">Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</a></p><p><b>value</b>: 0.818 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Total Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm30C-18m-1-Assay</b><a name=\"LongTerm30C-18m-1-Assay\"> </a><a name=\"hcLongTerm30C-18m-1-Assay\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#ObservationDefinition_7943795a-2abe-666f-545f-133e23b97119\">ObservationDefinition/7943795a-2abe-666f-545f-133e23b97119</a></p><p><b>status</b>: final</p><p><b>code</b>: Assay <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#ASSAY)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#Substance_a3fdc23b-6c16-2e65-481e-3fc895b37b87\">Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-batch-analysis-pq-ex1-prod.html#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\">Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</a></p><p><b>value</b>: 0.118 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm30C-18m-1-Identification</b><a name=\"LongTerm30C-18m-1-Identification\"> </a><a name=\"hcLongTerm30C-18m-1-Identification\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#ObservationDefinition_6b96124b-1a44-0b6b-6783-d6c49360230b\">ObservationDefinition/6b96124b-1a44-0b6b-6783-d6c49360230b</a></p><p><b>status</b>: final</p><p><b>code</b>: Identification <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IDT)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#Substance_a3fdc23b-6c16-2e65-481e-3fc895b37b87\">Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-batch-analysis-pq-ex1-prod.html#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\">Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</a></p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote></div>"
            },
            "contained" : [
              {
                "resourceType" : "Observation",
                "id" : "LongTerm30C-18m-1-Description",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/559ffdc3-349b-a4a3-a651-ce2715f08d69"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Description
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "DESC",
                      "display" : "Description"
                    }
                  ],
                  "text" : "Description"
                },
                "subject" : {
                  "reference" : "Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Substance/actual-batch-substance
                  {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
                  }
                ],
                "valueCodeableConcept" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
                {
                  "text" : "Complies"
                }
              },
              {
                "resourceType" : "Observation",
                "id" : "LongTerm30C-18m-1-Impurity1",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Impurities
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "DGP",
                      "display" : "Degradation Products"
                    }
                  ],
                  "text" : "Degradation Products"
                },
                "subject" : {
                  "reference" : "Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Substance/actual-batch-substance
                  {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
                  }
                ],
                "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
                {
                  "value" : 0.118,
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                },
                "component" : [
                  {
                    "code" : {
                      "coding" : [
                        {
                          "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                          "code" : "IMP",
                          "display" : "Impurity"
                        }
                      ]
                    },
                    "valueCodeableConcept" : {
                      "text" : "Impurity"
                    }
                  }
                ]
              },
              //  could have the code of an impurity substance, or could have an extension to point to it as a resource
              {
                "resourceType" : "Observation",
                "id" : "LongTerm30C-18m-1-Impurity2",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Impurities
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Impurities",
                      "display" : "Impurities"
                    }
                  ],
                  "text" : "Impurities"
                },
                "subject" : {
                  "reference" : "Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Substance/actual-batch-substance
                  {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
                  }
                ],
                "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
                {
                  "value" : 0.218,
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                },
                "component" : [
                  {
                    "code" : {
                      "coding" : [
                        {
                          "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                          "code" : "IMP",
                          "display" : "Impurity"
                        }
                      ]
                    },
                    "valueCodeableConcept" : {
                      "text" : "Impurity 2"
                    }
                  }
                ]
              },
              {
                "resourceType" : "Observation",
                "id" : "LongTerm30C-18m-1-ImpurityUnspecified",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Impurities
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Impurities",
                      "display" : "Impurities"
                    }
                  ],
                  "text" : "Impurities"
                },
                "subject" : {
                  "reference" : "Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Substance/actual-batch-substance
                  {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
                  }
                ],
                "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
                {
                  "value" : 0.0518,
                  "comparator" : "<",
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                },
                "component" : [
                  {
                    "code" : {
                      "coding" : [
                        {
                          "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                          "code" : "IMP",
                          "display" : "Impurity"
                        }
                      ]
                    },
                    "valueCodeableConcept" : {
                      "text" : "Any Unspecified Impurity"
                    }
                  }
                ]
              },
              {
                "resourceType" : "Observation",
                "id" : "LongTerm30C-18m-1-ImpurityTotal",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Impurities
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Impurities",
                      "display" : "Impurities"
                    }
                  ],
                  "text" : "Impurities"
                },
                "subject" : {
                  "reference" : "Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Substance/actual-batch-substance
                  {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
                  }
                ],
                "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
                {
                  "value" : 0.818,
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                },
                "component" : [
                  {
                    "code" : {
                      "coding" : [
                        {
                          "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                          "code" : "IMP",
                          "display" : "Impurity"
                        }
                      ]
                    },
                    "valueCodeableConcept" : {
                      "text" : "Total Impurities"
                    }
                  }
                ]
              },
              {
                "resourceType" : "Observation",
                "id" : "LongTerm30C-18m-1-Assay",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/7943795a-2abe-666f-545f-133e23b97119"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Assay
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "ASSAY",
                      "display" : "Assay"
                    }
                  ]
                },
                "subject" : {
                  "reference" : "Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Substance/actual-batch-substance
                  {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
                  }
                ],
                "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
                {
                  "value" : 0.118,
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                }
              },
              {
                "resourceType" : "Observation",
                "id" : "LongTerm30C-18m-1-Identification",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/6b96124b-1a44-0b6b-6783-d6c49360230b"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Identification
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "IDT",
                      "display" : "Identification"
                    }
                  ],
                  "text" : "Identification"
                },
                "subject" : {
                  "reference" : "Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Substance/actual-batch-substance
                  {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
                  }
                ],
                "valueCodeableConcept" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
                {
                  "text" : "Complies"
                }
              }
            ],
            "extension" : [
              //  use a standard extension to say what plan this is being done for. However it doesn't link to the step of that plan
                         that would mean using sub-ActivityDefintions probably
              {
                "url" : "http://hl7.org/fhir/StructureDefinition/workflow-triggeredBy",
                "valueReference" : {
                  "reference" : "ActivityDefinition/c9b53a46-2f61-7b3f-5780-5f5c79a47f12"
                }
              }
            ],
            "status" : "final",
            "code" : // ActivityDefinition/activityLongTerm30X-18
            {
              "text" : "Long-term - 30°C/65% RH - 18 months (X)"
            },
            "subject" : {
              "reference" : "Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/actual-batch-substance
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "specimen" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "reference" : "Specimen/7aa5fdea-17d7-29f1-1ed4-5c05eb62285a"
            },
            "hasMember" : [
              // Specimen/stability18months-1
              {
                "reference" : "#LongTerm30C-18m-1-Description"
              },
              {
                "reference" : "#LongTerm30C-18m-1-Assay"
              },
              {
                "reference" : "#LongTerm30C-18m-1-Impurity1"
              },
              {
                "reference" : "#LongTerm30C-18m-1-Impurity2"
              },
              {
                "reference" : "#LongTerm30C-18m-1-ImpurityUnspecified"
              },
              {
                "reference" : "#LongTerm30C-18m-1-ImpurityTotal"
              },
              {
                "reference" : "#LongTerm30C-18m-1-Identification"
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:1b25eb25-9149-02f6-9676-c87f90c64904",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "1b25eb25-9149-02f6-9676-c87f90c64904",
            "text" : // LongTerm30C-18m-2
            {
              "status" : "extensions",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_1b25eb25-9149-02f6-9676-c87f90c64904\"> </a><p><b>Generated Narrative: Observation</b><a name=\"1b25eb25-9149-02f6-9676-c87f90c64904\"> </a><a name=\"hc1b25eb25-9149-02f6-9676-c87f90c64904\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;1b25eb25-9149-02f6-9676-c87f90c64904&quot; </p></div><p><b>Triggered by</b>: See on this page: ActivityDefinition/c9b53a46-2f61-7b3f-5780-5f5c79a47f12</p><p><b>status</b>: final</p><p><b>code</b>: Long-term - 30°C/65% RH - 18 months (X) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>subject</b>: See on this page: Substance/cbcecab6-374c-396f-29be-877da7285e8d</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>specimen</b>: See on this page: Specimen/872a645f-120e-44c0-62c0-9be05acf543b</p><p><b>hasMember</b>: </p><ul><li><a name=\"hcLongTerm30C-18m-2-Description\"> </a></li><li><a name=\"hcLongTerm30C-18m-2-Assay\"> </a></li><li><a name=\"hcLongTerm30C-18m-2-Impurity1\"> </a></li><li><a name=\"hcLongTerm30C-18m-2-Impurity2\"> </a></li><li><a name=\"hcLongTerm30C-18m-2-ImpurityUnspecified\"> </a></li><li><a name=\"hcLongTerm30C-18m-2-ImpurityTotal\"> </a></li><li><a name=\"hcLongTerm30C-18m-2-Identification\"> </a></li></ul><blockquote><p/><p><a name=\"LongTerm30C-18m-2-Description\"> </a></p><p><a name=\"hcLongTerm30C-18m-2-Description\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/559ffdc3-349b-a4a3-a651-ce2715f08d69</p><p><b>status</b>: final</p><p><b>code</b>: Description <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DESC)</span></p><p><b>subject</b>: See on this page: Substance/cbcecab6-374c-396f-29be-877da7285e8d</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><blockquote><p/><p><a name=\"LongTerm30C-18m-2-Assay\"> </a></p><p><a name=\"hcLongTerm30C-18m-2-Assay\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/7943795a-2abe-666f-545f-133e23b97119</p><p><b>status</b>: final</p><p><b>code</b>: Assay <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#ASSAY)</span></p><p><b>subject</b>: See on this page: Substance/cbcecab6-374c-396f-29be-877da7285e8d</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.118 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p></blockquote><blockquote><p/><p><a name=\"LongTerm30C-18m-2-Impurity1\"> </a></p><p><a name=\"hcLongTerm30C-18m-2-Impurity1\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Substance/cbcecab6-374c-396f-29be-877da7285e8d</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.118 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p/><p><a name=\"LongTerm30C-18m-2-Impurity2\"> </a></p><p><a name=\"hcLongTerm30C-18m-2-Impurity2\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: See on this page: Substance/cbcecab6-374c-396f-29be-877da7285e8d</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.218 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 2 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p/><p><a name=\"LongTerm30C-18m-2-ImpurityUnspecified\"> </a></p><p><a name=\"hcLongTerm30C-18m-2-ImpurityUnspecified\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: See on this page: Substance/cbcecab6-374c-396f-29be-877da7285e8d</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: &lt;0.0518 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Any Unspecified Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p/><p><a name=\"LongTerm30C-18m-2-ImpurityTotal\"> </a></p><p><a name=\"hcLongTerm30C-18m-2-ImpurityTotal\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: See on this page: Substance/cbcecab6-374c-396f-29be-877da7285e8d</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.818 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Total Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p/><p><a name=\"LongTerm30C-18m-2-Identification\"> </a></p><p><a name=\"hcLongTerm30C-18m-2-Identification\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/6b96124b-1a44-0b6b-6783-d6c49360230b</p><p><b>status</b>: final</p><p><b>code</b>: Identification <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IDT)</span></p><p><b>subject</b>: See on this page: Substance/cbcecab6-374c-396f-29be-877da7285e8d</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm30C-18m-2-Description</b><a name=\"LongTerm30C-18m-2-Description\"> </a><a name=\"hcLongTerm30C-18m-2-Description\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#ObservationDefinition_559ffdc3-349b-a4a3-a651-ce2715f08d69\">ObservationDefinition/559ffdc3-349b-a4a3-a651-ce2715f08d69</a></p><p><b>status</b>: final</p><p><b>code</b>: Description <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DESC)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#Substance_cbcecab6-374c-396f-29be-877da7285e8d\">Substance/cbcecab6-374c-396f-29be-877da7285e8d</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-batch-analysis-pq-ex1-prod.html#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\">Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</a></p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm30C-18m-2-Impurity1</b><a name=\"LongTerm30C-18m-2-Impurity1\"> </a><a name=\"hcLongTerm30C-18m-2-Impurity1\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_73d9d304-a0b8-31b6-1165-346563b9305e\">ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</a></p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#Substance_cbcecab6-374c-396f-29be-877da7285e8d\">Substance/cbcecab6-374c-396f-29be-877da7285e8d</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-batch-analysis-pq-ex1-prod.html#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\">Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</a></p><p><b>value</b>: 0.118 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm30C-18m-2-Impurity2</b><a name=\"LongTerm30C-18m-2-Impurity2\"> </a><a name=\"hcLongTerm30C-18m-2-Impurity2\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_73d9d304-a0b8-31b6-1165-346563b9305e\">ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</a></p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#Substance_cbcecab6-374c-396f-29be-877da7285e8d\">Substance/cbcecab6-374c-396f-29be-877da7285e8d</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-batch-analysis-pq-ex1-prod.html#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\">Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</a></p><p><b>value</b>: 0.218 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 2 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm30C-18m-2-ImpurityUnspecified</b><a name=\"LongTerm30C-18m-2-ImpurityUnspecified\"> </a><a name=\"hcLongTerm30C-18m-2-ImpurityUnspecified\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_73d9d304-a0b8-31b6-1165-346563b9305e\">ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</a></p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#Substance_cbcecab6-374c-396f-29be-877da7285e8d\">Substance/cbcecab6-374c-396f-29be-877da7285e8d</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-batch-analysis-pq-ex1-prod.html#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\">Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</a></p><p><b>value</b>: &lt;0.0518 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Any Unspecified Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm30C-18m-2-ImpurityTotal</b><a name=\"LongTerm30C-18m-2-ImpurityTotal\"> </a><a name=\"hcLongTerm30C-18m-2-ImpurityTotal\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_73d9d304-a0b8-31b6-1165-346563b9305e\">ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</a></p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#Substance_cbcecab6-374c-396f-29be-877da7285e8d\">Substance/cbcecab6-374c-396f-29be-877da7285e8d</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-batch-analysis-pq-ex1-prod.html#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\">Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</a></p><p><b>value</b>: 0.818 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Total Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm30C-18m-2-Assay</b><a name=\"LongTerm30C-18m-2-Assay\"> </a><a name=\"hcLongTerm30C-18m-2-Assay\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#ObservationDefinition_7943795a-2abe-666f-545f-133e23b97119\">ObservationDefinition/7943795a-2abe-666f-545f-133e23b97119</a></p><p><b>status</b>: final</p><p><b>code</b>: Assay <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#ASSAY)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#Substance_cbcecab6-374c-396f-29be-877da7285e8d\">Substance/cbcecab6-374c-396f-29be-877da7285e8d</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-batch-analysis-pq-ex1-prod.html#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\">Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</a></p><p><b>value</b>: 0.118 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm30C-18m-2-Identification</b><a name=\"LongTerm30C-18m-2-Identification\"> </a><a name=\"hcLongTerm30C-18m-2-Identification\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#ObservationDefinition_6b96124b-1a44-0b6b-6783-d6c49360230b\">ObservationDefinition/6b96124b-1a44-0b6b-6783-d6c49360230b</a></p><p><b>status</b>: final</p><p><b>code</b>: Identification <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IDT)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#Substance_cbcecab6-374c-396f-29be-877da7285e8d\">Substance/cbcecab6-374c-396f-29be-877da7285e8d</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-batch-analysis-pq-ex1-prod.html#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\">Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</a></p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote></div>"
            },
            "contained" : [
              {
                "resourceType" : "Observation",
                "id" : "LongTerm30C-18m-2-Description",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/559ffdc3-349b-a4a3-a651-ce2715f08d69"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Description
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "DESC",
                      "display" : "Description"
                    }
                  ],
                  "text" : "Description"
                },
                "subject" : {
                  "reference" : "Substance/cbcecab6-374c-396f-29be-877da7285e8d"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Substance/actual-batch-substance-2
                  {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
                  }
                ],
                "valueCodeableConcept" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
                {
                  "text" : "Complies"
                }
              },
              {
                "resourceType" : "Observation",
                "id" : "LongTerm30C-18m-2-Impurity1",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Impurities
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "DGP",
                      "display" : "Degradation Products"
                    }
                  ],
                  "text" : "Degradation Products"
                },
                "subject" : {
                  "reference" : "Substance/cbcecab6-374c-396f-29be-877da7285e8d"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Substance/actual-batch-substance-2
                  {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
                  }
                ],
                "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
                {
                  "value" : 0.118,
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                },
                "component" : [
                  {
                    "code" : {
                      "coding" : [
                        {
                          "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                          "code" : "IMP",
                          "display" : "Impurity"
                        }
                      ]
                    },
                    "valueCodeableConcept" : {
                      "text" : "Impurity"
                    }
                  }
                ]
              },
              //  could have the code of an impurity substance, or could have an extension to point to it as a resource
              {
                "resourceType" : "Observation",
                "id" : "LongTerm30C-18m-2-Impurity2",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Impurities
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Impurities",
                      "display" : "Impurities"
                    }
                  ],
                  "text" : "Impurities"
                },
                "subject" : {
                  "reference" : "Substance/cbcecab6-374c-396f-29be-877da7285e8d"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Substance/actual-batch-substance-2
                  {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
                  }
                ],
                "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
                {
                  "value" : 0.218,
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                },
                "component" : [
                  {
                    "code" : {
                      "coding" : [
                        {
                          "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                          "code" : "IMP",
                          "display" : "Impurity"
                        }
                      ]
                    },
                    "valueCodeableConcept" : {
                      "text" : "Impurity 2"
                    }
                  }
                ]
              },
              {
                "resourceType" : "Observation",
                "id" : "LongTerm30C-18m-2-ImpurityUnspecified",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Impurities
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Impurities",
                      "display" : "Impurities"
                    }
                  ],
                  "text" : "Impurities"
                },
                "subject" : {
                  "reference" : "Substance/cbcecab6-374c-396f-29be-877da7285e8d"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Substance/actual-batch-substance-2
                  {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
                  }
                ],
                "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
                {
                  "value" : 0.0518,
                  "comparator" : "<",
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                },
                "component" : [
                  {
                    "code" : {
                      "coding" : [
                        {
                          "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                          "code" : "IMP",
                          "display" : "Impurity"
                        }
                      ]
                    },
                    "valueCodeableConcept" : {
                      "text" : "Any Unspecified Impurity"
                    }
                  }
                ]
              },
              {
                "resourceType" : "Observation",
                "id" : "LongTerm30C-18m-2-ImpurityTotal",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Impurities
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Impurities",
                      "display" : "Impurities"
                    }
                  ],
                  "text" : "Impurities"
                },
                "subject" : {
                  "reference" : "Substance/cbcecab6-374c-396f-29be-877da7285e8d"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Substance/actual-batch-substance-2
                  {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
                  }
                ],
                "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
                {
                  "value" : 0.818,
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                },
                "component" : [
                  {
                    "code" : {
                      "coding" : [
                        {
                          "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                          "code" : "IMP",
                          "display" : "Impurity"
                        }
                      ]
                    },
                    "valueCodeableConcept" : {
                      "text" : "Total Impurities"
                    }
                  }
                ]
              },
              {
                "resourceType" : "Observation",
                "id" : "LongTerm30C-18m-2-Assay",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/7943795a-2abe-666f-545f-133e23b97119"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Assay
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "ASSAY",
                      "display" : "Assay"
                    }
                  ]
                },
                "subject" : {
                  "reference" : "Substance/cbcecab6-374c-396f-29be-877da7285e8d"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Substance/actual-batch-substance-2
                  {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
                  }
                ],
                "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
                {
                  "value" : 0.118,
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                }
              },
              {
                "resourceType" : "Observation",
                "id" : "LongTerm30C-18m-2-Identification",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/6b96124b-1a44-0b6b-6783-d6c49360230b"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Identification
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "IDT",
                      "display" : "Identification"
                    }
                  ],
                  "text" : "Identification"
                },
                "subject" : {
                  "reference" : "Substance/cbcecab6-374c-396f-29be-877da7285e8d"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Substance/actual-batch-substance-2
                  {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
                  }
                ],
                "valueCodeableConcept" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
                {
                  "text" : "Complies"
                }
              }
            ],
            "extension" : [
              //  use a standard extension to say what plan this is being done for. However it doesn't link to the step of that plan
                         that would mean using sub-ActivityDefintions probably
              {
                "url" : "http://hl7.org/fhir/StructureDefinition/workflow-triggeredBy",
                "valueReference" : {
                  "reference" : "ActivityDefinition/c9b53a46-2f61-7b3f-5780-5f5c79a47f12"
                }
              }
            ],
            "status" : "final",
            "code" : // ActivityDefinition/activityLongTerm30X-18
            {
              "text" : "Long-term - 30°C/65% RH - 18 months (X)"
            },
            "subject" : {
              "reference" : "Substance/cbcecab6-374c-396f-29be-877da7285e8d"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/actual-batch-substance-2
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "specimen" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "reference" : "Specimen/872a645f-120e-44c0-62c0-9be05acf543b"
            },
            "hasMember" : [
              // Specimen/stability18months-2
              {
                "reference" : "#LongTerm30C-18m-2-Description"
              },
              {
                "reference" : "#LongTerm30C-18m-2-Assay"
              },
              {
                "reference" : "#LongTerm30C-18m-2-Impurity1"
              },
              {
                "reference" : "#LongTerm30C-18m-2-Impurity2"
              },
              {
                "reference" : "#LongTerm30C-18m-2-ImpurityUnspecified"
              },
              {
                "reference" : "#LongTerm30C-18m-2-ImpurityTotal"
              },
              {
                "reference" : "#LongTerm30C-18m-2-Identification"
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:004ed877-7729-834e-3b6b-a2cf4bdb2377",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "004ed877-7729-834e-3b6b-a2cf4bdb2377",
            "text" : // LongTerm30C-18m-3
            {
              "status" : "extensions",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_004ed877-7729-834e-3b6b-a2cf4bdb2377\"> </a><p><b>Generated Narrative: Observation</b><a name=\"004ed877-7729-834e-3b6b-a2cf4bdb2377\"> </a><a name=\"hc004ed877-7729-834e-3b6b-a2cf4bdb2377\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;004ed877-7729-834e-3b6b-a2cf4bdb2377&quot; </p></div><p><b>Triggered by</b>: See on this page: ActivityDefinition/c9b53a46-2f61-7b3f-5780-5f5c79a47f12</p><p><b>status</b>: final</p><p><b>code</b>: Long-term - 30°C/65% RH - 18 months (X) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>subject</b>: See on this page: Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>specimen</b>: See on this page: Specimen/7c06a03c-9cf7-2e1b-a236-d60038f1439b</p><p><b>hasMember</b>: </p><ul><li><a name=\"hcLongTerm30C-18m-3-Description\"> </a></li><li><a name=\"hcLongTerm30C-18m-3-Assay\"> </a></li><li><a name=\"hcLongTerm30C-18m-3-Impurity1\"> </a></li><li><a name=\"hcLongTerm30C-18m-3-Impurity2\"> </a></li><li><a name=\"hcLongTerm30C-18m-3-ImpurityUnspecified\"> </a></li><li><a name=\"hcLongTerm30C-18m-3-ImpurityTotal\"> </a></li><li><a name=\"hcLongTerm30C-18m-3-Identification\"> </a></li></ul><blockquote><p/><p><a name=\"LongTerm30C-18m-3-Description\"> </a></p><p><a name=\"hcLongTerm30C-18m-3-Description\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/559ffdc3-349b-a4a3-a651-ce2715f08d69</p><p><b>status</b>: final</p><p><b>code</b>: Description <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DESC)</span></p><p><b>subject</b>: See on this page: Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><blockquote><p/><p><a name=\"LongTerm30C-18m-3-Assay\"> </a></p><p><a name=\"hcLongTerm30C-18m-3-Assay\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/7943795a-2abe-666f-545f-133e23b97119</p><p><b>status</b>: final</p><p><b>code</b>: Assay <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#ASSAY)</span></p><p><b>subject</b>: See on this page: Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.118 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p></blockquote><blockquote><p/><p><a name=\"LongTerm30C-18m-3-Impurity1\"> </a></p><p><a name=\"hcLongTerm30C-18m-3-Impurity1\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.118 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p/><p><a name=\"LongTerm30C-18m-3-Impurity2\"> </a></p><p><a name=\"hcLongTerm30C-18m-3-Impurity2\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: See on this page: Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.218 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 2 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p/><p><a name=\"LongTerm30C-18m-3-ImpurityUnspecified\"> </a></p><p><a name=\"hcLongTerm30C-18m-3-ImpurityUnspecified\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: See on this page: Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: &lt;0.0518 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Any Unspecified Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p/><p><a name=\"LongTerm30C-18m-3-ImpurityTotal\"> </a></p><p><a name=\"hcLongTerm30C-18m-3-ImpurityTotal\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: See on this page: Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.818 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Total Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p/><p><a name=\"LongTerm30C-18m-3-Identification\"> </a></p><p><a name=\"hcLongTerm30C-18m-3-Identification\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/6b96124b-1a44-0b6b-6783-d6c49360230b</p><p><b>status</b>: final</p><p><b>code</b>: Identification <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IDT)</span></p><p><b>subject</b>: See on this page: Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm30C-18m-3-Description</b><a name=\"LongTerm30C-18m-3-Description\"> </a><a name=\"hcLongTerm30C-18m-3-Description\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#ObservationDefinition_559ffdc3-349b-a4a3-a651-ce2715f08d69\">ObservationDefinition/559ffdc3-349b-a4a3-a651-ce2715f08d69</a></p><p><b>status</b>: final</p><p><b>code</b>: Description <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DESC)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#Substance_ae1f3b4c-4f14-1460-6903-7260959ea2cd\">Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-batch-analysis-pq-ex1-prod.html#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\">Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</a></p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm30C-18m-3-Impurity1</b><a name=\"LongTerm30C-18m-3-Impurity1\"> </a><a name=\"hcLongTerm30C-18m-3-Impurity1\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_73d9d304-a0b8-31b6-1165-346563b9305e\">ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</a></p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#Substance_ae1f3b4c-4f14-1460-6903-7260959ea2cd\">Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-batch-analysis-pq-ex1-prod.html#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\">Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</a></p><p><b>value</b>: 0.118 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm30C-18m-3-Impurity2</b><a name=\"LongTerm30C-18m-3-Impurity2\"> </a><a name=\"hcLongTerm30C-18m-3-Impurity2\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_73d9d304-a0b8-31b6-1165-346563b9305e\">ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</a></p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#Substance_ae1f3b4c-4f14-1460-6903-7260959ea2cd\">Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-batch-analysis-pq-ex1-prod.html#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\">Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</a></p><p><b>value</b>: 0.218 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 2 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm30C-18m-3-ImpurityUnspecified</b><a name=\"LongTerm30C-18m-3-ImpurityUnspecified\"> </a><a name=\"hcLongTerm30C-18m-3-ImpurityUnspecified\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_73d9d304-a0b8-31b6-1165-346563b9305e\">ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</a></p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#Substance_ae1f3b4c-4f14-1460-6903-7260959ea2cd\">Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-batch-analysis-pq-ex1-prod.html#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\">Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</a></p><p><b>value</b>: &lt;0.0518 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Any Unspecified Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm30C-18m-3-ImpurityTotal</b><a name=\"LongTerm30C-18m-3-ImpurityTotal\"> </a><a name=\"hcLongTerm30C-18m-3-ImpurityTotal\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_73d9d304-a0b8-31b6-1165-346563b9305e\">ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</a></p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#Substance_ae1f3b4c-4f14-1460-6903-7260959ea2cd\">Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-batch-analysis-pq-ex1-prod.html#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\">Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</a></p><p><b>value</b>: 0.818 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Total Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm30C-18m-3-Assay</b><a name=\"LongTerm30C-18m-3-Assay\"> </a><a name=\"hcLongTerm30C-18m-3-Assay\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#ObservationDefinition_7943795a-2abe-666f-545f-133e23b97119\">ObservationDefinition/7943795a-2abe-666f-545f-133e23b97119</a></p><p><b>status</b>: final</p><p><b>code</b>: Assay <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#ASSAY)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#Substance_ae1f3b4c-4f14-1460-6903-7260959ea2cd\">Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-batch-analysis-pq-ex1-prod.html#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\">Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</a></p><p><b>value</b>: 0.118 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #LongTerm30C-18m-3-Identification</b><a name=\"LongTerm30C-18m-3-Identification\"> </a><a name=\"hcLongTerm30C-18m-3-Identification\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#ObservationDefinition_6b96124b-1a44-0b6b-6783-d6c49360230b\">ObservationDefinition/6b96124b-1a44-0b6b-6783-d6c49360230b</a></p><p><b>status</b>: final</p><p><b>code</b>: Identification <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IDT)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#Substance_ae1f3b4c-4f14-1460-6903-7260959ea2cd\">Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-batch-analysis-pq-ex1-prod.html#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\">Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</a></p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote></div>"
            },
            "contained" : [
              {
                "resourceType" : "Observation",
                "id" : "LongTerm30C-18m-3-Description",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/559ffdc3-349b-a4a3-a651-ce2715f08d69"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Description
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "DESC",
                      "display" : "Description"
                    }
                  ],
                  "text" : "Description"
                },
                "subject" : {
                  "reference" : "Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Substance/actual-batch-substance-3
                  {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
                  }
                ],
                "valueCodeableConcept" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
                {
                  "text" : "Complies"
                }
              },
              {
                "resourceType" : "Observation",
                "id" : "LongTerm30C-18m-3-Impurity1",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Impurities
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "DGP",
                      "display" : "Degradation Products"
                    }
                  ],
                  "text" : "Degradation Products"
                },
                "subject" : {
                  "reference" : "Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Substance/actual-batch-substance-3
                  {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
                  }
                ],
                "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
                {
                  "value" : 0.118,
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                },
                "component" : [
                  {
                    "code" : {
                      "coding" : [
                        {
                          "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                          "code" : "IMP",
                          "display" : "Impurity"
                        }
                      ]
                    },
                    "valueCodeableConcept" : {
                      "text" : "Impurity"
                    }
                  }
                ]
              },
              //  could have the code of an impurity substance, or could have an extension to point to it as a resource
              {
                "resourceType" : "Observation",
                "id" : "LongTerm30C-18m-3-Impurity2",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Impurities
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Impurities",
                      "display" : "Impurities"
                    }
                  ],
                  "text" : "Impurities"
                },
                "subject" : {
                  "reference" : "Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Substance/actual-batch-substance-3
                  {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
                  }
                ],
                "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
                {
                  "value" : 0.218,
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                },
                "component" : [
                  {
                    "code" : {
                      "coding" : [
                        {
                          "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                          "code" : "IMP",
                          "display" : "Impurity"
                        }
                      ]
                    },
                    "valueCodeableConcept" : {
                      "text" : "Impurity 2"
                    }
                  }
                ]
              },
              {
                "resourceType" : "Observation",
                "id" : "LongTerm30C-18m-3-ImpurityUnspecified",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Impurities
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Impurities",
                      "display" : "Impurities"
                    }
                  ],
                  "text" : "Impurities"
                },
                "subject" : {
                  "reference" : "Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Substance/actual-batch-substance-3
                  {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
                  }
                ],
                "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
                {
                  "value" : 0.0518,
                  "comparator" : "<",
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                },
                "component" : [
                  {
                    "code" : {
                      "coding" : [
                        {
                          "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                          "code" : "IMP",
                          "display" : "Impurity"
                        }
                      ]
                    },
                    "valueCodeableConcept" : {
                      "text" : "Any Unspecified Impurity"
                    }
                  }
                ]
              },
              {
                "resourceType" : "Observation",
                "id" : "LongTerm30C-18m-3-ImpurityTotal",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Impurities
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Impurities",
                      "display" : "Impurities"
                    }
                  ],
                  "text" : "Impurities"
                },
                "subject" : {
                  "reference" : "Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Substance/actual-batch-substance-3
                  {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
                  }
                ],
                "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
                {
                  "value" : 0.818,
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                },
                "component" : [
                  {
                    "code" : {
                      "coding" : [
                        {
                          "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                          "code" : "IMP",
                          "display" : "Impurity"
                        }
                      ]
                    },
                    "valueCodeableConcept" : {
                      "text" : "Total Impurities"
                    }
                  }
                ]
              },
              {
                "resourceType" : "Observation",
                "id" : "LongTerm30C-18m-3-Assay",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/7943795a-2abe-666f-545f-133e23b97119"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Assay
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "ASSAY",
                      "display" : "Assay"
                    }
                  ]
                },
                "subject" : {
                  "reference" : "Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Substance/actual-batch-substance-3
                  {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
                  }
                ],
                "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
                {
                  "value" : 0.118,
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                }
              },
              {
                "resourceType" : "Observation",
                "id" : "LongTerm30C-18m-3-Identification",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/6b96124b-1a44-0b6b-6783-d6c49360230b"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Identification
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "IDT",
                      "display" : "Identification"
                    }
                  ],
                  "text" : "Identification"
                },
                "subject" : {
                  "reference" : "Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Substance/actual-batch-substance-3
                  {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
                  }
                ],
                "valueCodeableConcept" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
                {
                  "text" : "Complies"
                }
              }
            ],
            "extension" : [
              //  use a standard extension to say what plan this is being done for. However it doesn't link to the step of that plan
                         that would mean using sub-ActivityDefintions probably
              {
                "url" : "http://hl7.org/fhir/StructureDefinition/workflow-triggeredBy",
                "valueReference" : {
                  "reference" : "ActivityDefinition/c9b53a46-2f61-7b3f-5780-5f5c79a47f12"
                }
              }
            ],
            "status" : "final",
            "code" : // ActivityDefinition/activityLongTerm30X-18
            {
              "text" : "Long-term - 30°C/65% RH - 18 months (X)"
            },
            "subject" : {
              "reference" : "Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/actual-batch-substance-3
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "specimen" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "reference" : "Specimen/7c06a03c-9cf7-2e1b-a236-d60038f1439b"
            },
            "hasMember" : [
              // Specimen/stability18months-3
              {
                "reference" : "#LongTerm30C-18m-3-Description"
              },
              {
                "reference" : "#LongTerm30C-18m-3-Assay"
              },
              {
                "reference" : "#LongTerm30C-18m-3-Impurity1"
              },
              {
                "reference" : "#LongTerm30C-18m-3-Impurity2"
              },
              {
                "reference" : "#LongTerm30C-18m-3-ImpurityUnspecified"
              },
              {
                "reference" : "#LongTerm30C-18m-3-ImpurityTotal"
              },
              {
                "reference" : "#LongTerm30C-18m-3-Identification"
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:b04c9321-069c-4da8-8ed0-86337ea22c30",
          "resource" : {
            "resourceType" : "Specimen",
            "id" : "b04c9321-069c-4da8-8ed0-86337ea22c30",
            "text" : // acceleratedInitial-3m-1
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Specimen_b04c9321-069c-4da8-8ed0-86337ea22c30\"> </a><p><b>Generated Narrative: Specimen</b><a name=\"b04c9321-069c-4da8-8ed0-86337ea22c30\"> </a><a name=\"hcb04c9321-069c-4da8-8ed0-86337ea22c30\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Specimen &quot;b04c9321-069c-4da8-8ed0-86337ea22c30&quot; </p></div><h3>Collections</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Collected[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>2020-06</td></tr></table><blockquote><p><b>processing</b></p><p><b>description</b>: No storage</p></blockquote><blockquote><p><b>processing</b></p><p><b>description</b>: 40°C/75% RH</p></blockquote></div>"
            },
            "collection" : {
              "collectedDateTime" : "2020-06"
            },
            "processing" : [
              {
                "description" : "No storage"
              },
              {
                "description" : "40°C/75% RH"
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:f958e1e9-6023-4e39-2ffe-a9c8f135a2dd",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "f958e1e9-6023-4e39-2ffe-a9c8f135a2dd",
            "text" : // Accelerated40C-3m
            {
              "status" : "extensions",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_f958e1e9-6023-4e39-2ffe-a9c8f135a2dd\"> </a><p><b>Generated Narrative: Observation</b><a name=\"f958e1e9-6023-4e39-2ffe-a9c8f135a2dd\"> </a><a name=\"hcf958e1e9-6023-4e39-2ffe-a9c8f135a2dd\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;f958e1e9-6023-4e39-2ffe-a9c8f135a2dd&quot; </p></div><p><b>Triggered by</b>: See on this page: ActivityDefinition/8a453cd8-1ac3-4c86-48c3-3e5ea9ee76a9</p><p><b>status</b>: final</p><p><b>code</b>: Accelerated - 40°C/67% RH - 3 months (X) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>subject</b>: See on this page: Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>specimen</b>: See on this page: Specimen/b04c9321-069c-4da8-8ed0-86337ea22c30</p><p><b>hasMember</b>: </p><ul><li><a name=\"hcAccelerated40C-3m-1-Description\"> </a></li><li><a name=\"hcAccelerated40C-3m-1-Assay\"> </a></li><li><a name=\"hcAccelerated40C-3m-1-Impurity1\"> </a></li><li><a name=\"hcAccelerated40C-3m-1-Impurity2\"> </a></li><li><a name=\"hcAccelerated40C-3m-1-ImpurityUnspecified\"> </a></li><li><a name=\"hcAccelerated40C-3m-1-ImpurityTotal\"> </a></li><li><a name=\"hcAccelerated40C-3m-1-Identification\"> </a></li></ul><blockquote><p/><p><a name=\"Accelerated40C-3m-1-Description\"> </a></p><p><a name=\"hcAccelerated40C-3m-1-Description\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/559ffdc3-349b-a4a3-a651-ce2715f08d69</p><p><b>status</b>: final</p><p><b>code</b>: Description <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DESC)</span></p><p><b>subject</b>: See on this page: Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: Doesn't comply <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><blockquote><p/><p><a name=\"Accelerated40C-3m-1-Assay\"> </a></p><p><a name=\"hcAccelerated40C-3m-1-Assay\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/7943795a-2abe-666f-545f-133e23b97119</p><p><b>status</b>: final</p><p><b>code</b>: Assay <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#ASSAY)</span></p><p><b>subject</b>: See on this page: Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.113 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p></blockquote><blockquote><p/><p><a name=\"Accelerated40C-3m-1-Impurity1\"> </a></p><p><a name=\"hcAccelerated40C-3m-1-Impurity1\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: See on this page: Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.113 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p/><p><a name=\"Accelerated40C-3m-1-Impurity2\"> </a></p><p><a name=\"hcAccelerated40C-3m-1-Impurity2\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: See on this page: Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.213 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 2 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p/><p><a name=\"Accelerated40C-3m-1-ImpurityUnspecified\"> </a></p><p><a name=\"hcAccelerated40C-3m-1-ImpurityUnspecified\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: See on this page: Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: &lt;0.0513 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Any Unspecified Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p/><p><a name=\"Accelerated40C-3m-1-ImpurityTotal\"> </a></p><p><a name=\"hcAccelerated40C-3m-1-ImpurityTotal\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: See on this page: Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 0.813 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Total Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p/><p><a name=\"Accelerated40C-3m-1-Identification\"> </a></p><p><a name=\"hcAccelerated40C-3m-1-Identification\"> </a></p><p><b>instantiates</b>: See on this page: ObservationDefinition/6b96124b-1a44-0b6b-6783-d6c49360230b</p><p><b>status</b>: final</p><p><b>code</b>: Identification <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IDT)</span></p><p><b>subject</b>: See on this page: Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #Accelerated40C-3m-1-Description</b><a name=\"Accelerated40C-3m-1-Description\"> </a><a name=\"hcAccelerated40C-3m-1-Description\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#ObservationDefinition_559ffdc3-349b-a4a3-a651-ce2715f08d69\">ObservationDefinition/559ffdc3-349b-a4a3-a651-ce2715f08d69</a></p><p><b>status</b>: final</p><p><b>code</b>: Description <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DESC)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#Substance_a3fdc23b-6c16-2e65-481e-3fc895b37b87\">Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-batch-analysis-pq-ex1-prod.html#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\">Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</a></p><p><b>value</b>: Doesn't comply <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #Accelerated40C-3m-1-Impurity1</b><a name=\"Accelerated40C-3m-1-Impurity1\"> </a><a name=\"hcAccelerated40C-3m-1-Impurity1\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_73d9d304-a0b8-31b6-1165-346563b9305e\">ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</a></p><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#Substance_a3fdc23b-6c16-2e65-481e-3fc895b37b87\">Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-batch-analysis-pq-ex1-prod.html#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\">Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</a></p><p><b>value</b>: 0.113 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #Accelerated40C-3m-1-Impurity2</b><a name=\"Accelerated40C-3m-1-Impurity2\"> </a><a name=\"hcAccelerated40C-3m-1-Impurity2\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_73d9d304-a0b8-31b6-1165-346563b9305e\">ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</a></p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#Substance_a3fdc23b-6c16-2e65-481e-3fc895b37b87\">Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-batch-analysis-pq-ex1-prod.html#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\">Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</a></p><p><b>value</b>: 0.213 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Impurity 2 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #Accelerated40C-3m-1-ImpurityUnspecified</b><a name=\"Accelerated40C-3m-1-ImpurityUnspecified\"> </a><a name=\"hcAccelerated40C-3m-1-ImpurityUnspecified\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_73d9d304-a0b8-31b6-1165-346563b9305e\">ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</a></p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#Substance_a3fdc23b-6c16-2e65-481e-3fc895b37b87\">Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-batch-analysis-pq-ex1-prod.html#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\">Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</a></p><p><b>value</b>: &lt;0.0513 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Any Unspecified Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #Accelerated40C-3m-1-ImpurityTotal</b><a name=\"Accelerated40C-3m-1-ImpurityTotal\"> </a><a name=\"hcAccelerated40C-3m-1-ImpurityTotal\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex1-prod.html#ObservationDefinition_73d9d304-a0b8-31b6-1165-346563b9305e\">ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e</a></p><p><b>status</b>: final</p><p><b>code</b>: Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Impurities)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#Substance_ae1f3b4c-4f14-1460-6903-7260959ea2cd\">Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-batch-analysis-pq-ex1-prod.html#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\">Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</a></p><p><b>value</b>: 0.813 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td><td>Total Impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #Accelerated40C-3m-1-Assay</b><a name=\"Accelerated40C-3m-1-Assay\"> </a><a name=\"hcAccelerated40C-3m-1-Assay\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#ObservationDefinition_7943795a-2abe-666f-545f-133e23b97119\">ObservationDefinition/7943795a-2abe-666f-545f-133e23b97119</a></p><p><b>status</b>: final</p><p><b>code</b>: Assay <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#ASSAY)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#Substance_ae1f3b4c-4f14-1460-6903-7260959ea2cd\">Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-batch-analysis-pq-ex1-prod.html#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\">Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</a></p><p><b>value</b>: 0.113 % w/w<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p></blockquote><hr/><blockquote><p><b>Generated Narrative: Observation #Accelerated40C-3m-1-Identification</b><a name=\"Accelerated40C-3m-1-Identification\"> </a><a name=\"hcAccelerated40C-3m-1-Identification\"> </a></p><p><b>instantiates</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#ObservationDefinition_6b96124b-1a44-0b6b-6783-d6c49360230b\">ObservationDefinition/6b96124b-1a44-0b6b-6783-d6c49360230b</a></p><p><b>status</b>: final</p><p><b>code</b>: Identification <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IDT)</span></p><p><b>subject</b>: <a href=\"Bundle-bundle-drug-stability-pq-ex2-sub.html#Substance_ae1f3b4c-4f14-1460-6903-7260959ea2cd\">Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"Bundle-bundle-batch-analysis-pq-ex1-prod.html#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\">Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</a></p><p><b>value</b>: Complies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote></div>"
            },
            "contained" : [
              {
                "resourceType" : "Observation",
                "id" : "Accelerated40C-3m-1-Description",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/559ffdc3-349b-a4a3-a651-ce2715f08d69"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Description
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "DESC",
                      "display" : "Description"
                    }
                  ],
                  "text" : "Description"
                },
                "subject" : {
                  "reference" : "Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Substance/actual-batch-substance
                  {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
                  }
                ],
                "valueCodeableConcept" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
                {
                  "text" : "Doesn't comply"
                }
              },
              {
                "resourceType" : "Observation",
                "id" : "Accelerated40C-3m-1-Impurity1",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Impurities
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "DGP",
                      "display" : "Degradation Products"
                    }
                  ],
                  "text" : "Degradation Products"
                },
                "subject" : {
                  "reference" : "Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Substance/actual-batch-substance
                  {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
                  }
                ],
                "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
                {
                  "value" : 0.113,
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                },
                "component" : [
                  {
                    "code" : {
                      "coding" : [
                        {
                          "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                          "code" : "IMP",
                          "display" : "Impurity"
                        }
                      ]
                    },
                    "valueCodeableConcept" : {
                      "text" : "Impurity"
                    }
                  }
                ]
              },
              //  could have the code of an impurity substance, or could have an extension to point to it as a resource
              {
                "resourceType" : "Observation",
                "id" : "Accelerated40C-3m-1-Impurity2",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Impurities
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Impurities",
                      "display" : "Impurities"
                    }
                  ],
                  "text" : "Impurities"
                },
                "subject" : {
                  "reference" : "Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Substance/actual-batch-substance
                  {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
                  }
                ],
                "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
                {
                  "value" : 0.213,
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                },
                "component" : [
                  {
                    "code" : {
                      "coding" : [
                        {
                          "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                          "code" : "IMP",
                          "display" : "Impurity"
                        }
                      ]
                    },
                    "valueCodeableConcept" : {
                      "text" : "Impurity 2"
                    }
                  }
                ]
              },
              {
                "resourceType" : "Observation",
                "id" : "Accelerated40C-3m-1-ImpurityUnspecified",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Impurities
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Impurities",
                      "display" : "Impurities"
                    }
                  ],
                  "text" : "Impurities"
                },
                "subject" : {
                  "reference" : "Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Substance/actual-batch-substance
                  {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
                  }
                ],
                "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
                {
                  "value" : 0.0513,
                  "comparator" : "<",
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                },
                "component" : [
                  {
                    "code" : {
                      "coding" : [
                        {
                          "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                          "code" : "IMP",
                          "display" : "Impurity"
                        }
                      ]
                    },
                    "valueCodeableConcept" : {
                      "text" : "Any Unspecified Impurity"
                    }
                  }
                ]
              },
              {
                "resourceType" : "Observation",
                "id" : "Accelerated40C-3m-1-ImpurityTotal",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/73d9d304-a0b8-31b6-1165-346563b9305e"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Impurities
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Impurities",
                      "display" : "Impurities"
                    }
                  ],
                  "text" : "Impurities"
                },
                "subject" : {
                  "reference" : "Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Substance/actual-batch-substance-3
                  {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
                  }
                ],
                "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
                {
                  "value" : 0.813,
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                },
                "component" : [
                  {
                    "code" : {
                      "coding" : [
                        {
                          "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                          "code" : "IMP",
                          "display" : "Impurity"
                        }
                      ]
                    },
                    "valueCodeableConcept" : {
                      "text" : "Total Impurities"
                    }
                  }
                ]
              },
              {
                "resourceType" : "Observation",
                "id" : "Accelerated40C-3m-1-Assay",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/7943795a-2abe-666f-545f-133e23b97119"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Assay
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "ASSAY",
                      "display" : "Assay"
                    }
                  ]
                },
                "subject" : {
                  "reference" : "Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Substance/actual-batch-substance-3
                  {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
                  }
                ],
                "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
                {
                  "value" : 0.113,
                  "unit" : "% w/w",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "%"
                }
              },
              {
                "resourceType" : "Observation",
                "id" : "Accelerated40C-3m-1-Identification",
                "instantiatesReference" : {
                  "reference" : "ObservationDefinition/6b96124b-1a44-0b6b-6783-d6c49360230b"
                },
                "status" : "final",
                "code" : // ObservationDefinition/Identification
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "IDT",
                      "display" : "Identification"
                    }
                  ],
                  "text" : "Identification"
                },
                "subject" : {
                  "reference" : "Substance/ae1f3b4c-4f14-1460-6903-7260959ea2cd"
                },
                "effectiveDateTime" : "2023-01-01T12:00:00Z",
                "performer" : [
                  // Substance/actual-batch-substance-3
                  {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
                  }
                ],
                "valueCodeableConcept" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
                {
                  "text" : "Complies"
                }
              }
            ],
            "extension" : [
              //  use a standard extension to say what plan this is being done for. However it doesn't link to the step of that plan
                         that would mean using sub-ActivityDefintions probably
              {
                "url" : "http://hl7.org/fhir/StructureDefinition/workflow-triggeredBy",
                "valueReference" : {
                  "reference" : "ActivityDefinition/8a453cd8-1ac3-4c86-48c3-3e5ea9ee76a9"
                }
              }
            ],
            "status" : "final",
            "code" : // ActivityDefinition/activityAccelerated40X-3
            {
              "text" : "Accelerated - 40°C/67% RH - 3 months (X)"
            },
            "subject" : {
              "reference" : "Substance/a3fdc23b-6c16-2e65-481e-3fc895b37b87"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Substance/actual-batch-substance
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "specimen" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "reference" : "Specimen/b04c9321-069c-4da8-8ed0-86337ea22c30"
            },
            "hasMember" : [
              // Specimen/acceleratedInitial-3m-1
              {
                "reference" : "#Accelerated40C-3m-1-Description"
              },
              {
                "reference" : "#Accelerated40C-3m-1-Assay"
              },
              {
                "reference" : "#Accelerated40C-3m-1-Impurity1"
              },
              {
                "reference" : "#Accelerated40C-3m-1-Impurity2"
              },
              {
                "reference" : "#Accelerated40C-3m-1-ImpurityUnspecified"
              },
              {
                "reference" : "#Accelerated40C-3m-1-ImpurityTotal"
              },
              {
                "reference" : "#Accelerated40C-3m-1-Identification"
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:62c1b1b4-8d15-26d2-57f9-25a2f60b6181",
          "resource" : {
            "resourceType" : "Organization",
            "id" : "62c1b1b4-8d15-26d2-57f9-25a2f60b6181",
            "text" : // manufacturer
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Organization_62c1b1b4-8d15-26d2-57f9-25a2f60b6181\"> </a><p><b>Generated Narrative: Organization</b><a name=\"62c1b1b4-8d15-26d2-57f9-25a2f60b6181\"> </a><a name=\"hc62c1b1b4-8d15-26d2-57f9-25a2f60b6181\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Organization &quot;62c1b1b4-8d15-26d2-57f9-25a2f60b6181&quot; </p></div><p><b>identifier</b>: <code>urn:oid:2.16.840.1.113883.4.82</code>/3003040516</p><p><b>active</b>: true</p><p><b>type</b>: Drug Substance Manufacture <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-organization-type.html\">Pharmaceutical Organization Type Codes</a>#drug-substance-manufacture)</span></p><p><b>name</b>: AAA Molybdenum Products, Inc.</p><h3>Contacts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Address</b></td></tr><tr><td style=\"display: none\">*</td><td>7233 W 116th Pl Ste C Broomfield Colorado 80020 USA </td></tr></table></div>"
            },
            "identifier" : [
              {
                "system" : "urn:oid:2.16.840.1.113883.4.82",
                "value" : "3003040516"
              }
            ],
            "active" : true,
            "type" : [
              //  FDA establishment identifier
              {
                "coding" : [
                  {
                    "system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-organization-type",
                    "code" : "drug-substance-manufacture",
                    "display" : "Drug Substance Manufacture"
                  }
                ]
              }
            ],
            "name" : "AAA Molybdenum Products, Inc.",
            "contact" : [
              {
                "address" : {
                  "line" : [
                    "7233 W 116th Pl",
                    "Ste C"
                  ],
                  "city" : "Broomfield",
                  "state" : "Colorado",
                  "postalCode" : "80020",
                  "country" : "USA"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:6049d921-9935-90b7-4efc-894a66483c00",
          "resource" : {
            "resourceType" : "Organization",
            "id" : "6049d921-9935-90b7-4efc-894a66483c00",
            "text" : // tester
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Organization_6049d921-9935-90b7-4efc-894a66483c00\"> </a><p><b>Generated Narrative: Organization</b><a name=\"6049d921-9935-90b7-4efc-894a66483c00\"> </a><a name=\"hc6049d921-9935-90b7-4efc-894a66483c00\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Organization &quot;6049d921-9935-90b7-4efc-894a66483c00&quot; </p></div><p><b>identifier</b>: <code>urn:oid:2.16.840.1.113883.4.82</code>/3007270600</p><p><b>active</b>: true</p><p><b>type</b>: Analytical Testing - Stability <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-organization-type.html\">Pharmaceutical Organization Type Codes</a>#analytical-testing-stability)</span></p><p><b>name</b>: Advanced Analytical Testing Laboratories Inc.</p><h3>Contacts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Address</b></td></tr><tr><td style=\"display: none\">*</td><td>30 Silverline Drive North Brunswick New Jersey 08902 USA </td></tr></table></div>"
            },
            "identifier" : [
              //  could also use assigner here, for #74
              {
                "system" : "urn:oid:2.16.840.1.113883.4.82",
                "value" : "3007270600"
              }
            ],
            "active" : true,
            "type" : [
              {
                "coding" : [
                  {
                    "system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-organization-type",
                    "code" : "analytical-testing-stability",
                    "display" : "Analytical Testing - Stability"
                  }
                ]
              }
            ],
            "name" : "Advanced Analytical Testing Laboratories Inc.",
            "contact" : [
              {
                "address" : {
                  "line" : [
                    "30 Silverline Drive"
                  ],
                  "city" : "North Brunswick",
                  "state" : "New Jersey",
                  "postalCode" : "08902",
                  "country" : "USA"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:2e3a85b5-790a-a108-3627-edf0ec6f1210",
          "resource" : {
            "resourceType" : "SubstanceDefinition",
            "id" : "2e3a85b5-790a-a108-3627-edf0ec6f1210",
            "text" : // substance1
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"SubstanceDefinition_2e3a85b5-790a-a108-3627-edf0ec6f1210\"> </a><p><b>Generated Narrative: SubstanceDefinition</b><a name=\"2e3a85b5-790a-a108-3627-edf0ec6f1210\"> </a><a name=\"hc2e3a85b5-790a-a108-3627-edf0ec6f1210\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource SubstanceDefinition &quot;2e3a85b5-790a-a108-3627-edf0ec6f1210&quot; </p></div><p><b>identifier</b>: <code>http://example.company.org/companySubstanceIdentifier</code>/4444455555</p><p><b>manufacturer</b>: See on this page: Organization/62c1b1b4-8d15-26d2-57f9-25a2f60b6181</p><h3>Names</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Name</b></td></tr><tr><td style=\"display: none\">*</td><td>Stelbatolol</td></tr></table></div>"
            },
            "identifier" : [
              {
                "system" : "http://example.company.org/companySubstanceIdentifier",
                "value" : "4444455555"
              }
            ],
            "manufacturer" : [
              {
                "extension" : [
                  {
                    "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-site-utilization-pq",
                    "valueCoding" : {
                      "system" : "http://terminology.hl7.org/CodeSystem/product-site-utilization-type",
                      "code" : "Release stability",
                      "display" : "Release stability"
                    }
                  }
                ],
                "reference" : "Organization/62c1b1b4-8d15-26d2-57f9-25a2f60b6181"
              }
            ],
            "name" : [
              // Organization/manufacturer
              {
                "name" : "Stelbatolol"
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:e2359a4e-3091-23f8-2242-87e701830d55",
          "resource" : {
            "resourceType" : "Organization",
            "id" : "e2359a4e-3091-23f8-2242-87e701830d55",
            "text" : // substance-manufacturer
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Organization_e2359a4e-3091-23f8-2242-87e701830d55\"> </a><p><b>Generated Narrative: Organization</b><a name=\"e2359a4e-3091-23f8-2242-87e701830d55\"> </a><a name=\"hce2359a4e-3091-23f8-2242-87e701830d55\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Organization &quot;e2359a4e-3091-23f8-2242-87e701830d55&quot; </p></div><p><b>identifier</b>: <code>urn:oid:2.16.840.1.113883.4.82</code>/3003040516</p><p><b>active</b>: true</p><p><b>type</b>: Drug Substance Manufacture <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-organization-type.html\">Pharmaceutical Organization Type Codes</a>#drug-substance-manufacture)</span></p><p><b>name</b>: AAA Molybdenum Products, Inc.</p><h3>Contacts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Address</b></td></tr><tr><td style=\"display: none\">*</td><td>7233 W 116th Pl Ste C Broomfield Colorado 80020 USA </td></tr></table></div>"
            },
            "identifier" : [
              {
                "system" : "urn:oid:2.16.840.1.113883.4.82",
                "value" : "3003040516"
              }
            ],
            "active" : true,
            "type" : [
              //  FDA establishment identifier
              {
                "coding" : [
                  {
                    "system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-organization-type",
                    "code" : "drug-substance-manufacture",
                    "display" : "Drug Substance Manufacture"
                  }
                ]
              }
            ],
            "name" : "AAA Molybdenum Products, Inc.",
            "contact" : [
              {
                "address" : {
                  "line" : [
                    "7233 W 116th Pl",
                    "Ste C"
                  ],
                  "city" : "Broomfield",
                  "state" : "Colorado",
                  "postalCode" : "80020",
                  "country" : "USA"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:378fbe5f-5926-3a5c-4c64-5428df877b08",
          "resource" : {
            "resourceType" : "Organization",
            "id" : "378fbe5f-5926-3a5c-4c64-5428df877b08",
            "text" : // testing lab
            // 378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\"> </a><p><b>Generated Narrative: Organization</b><a name=\"378fbe5f-5926-3a5c-4c64-5428df877b08\"> </a><a name=\"hc378fbe5f-5926-3a5c-4c64-5428df877b08\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Organization &quot;378fbe5f-5926-3a5c-4c64-5428df877b08&quot; </p></div><p><b>identifier</b>: <code>urn:oid:2.16.840.1.113883.4.82</code>/3007270600</p><p><b>active</b>: true</p><p><b>type</b>: Analytical Testing - Stability <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-organization-type.html\">Pharmaceutical Organization Type Codes</a>#analytical-testing-stability)</span></p><p><b>name</b>: Testing Lab</p></div>"
            },
            "identifier" : [
              {
                "system" : "urn:oid:2.16.840.1.113883.4.82",
                "value" : "3007270600"
              }
            ],
            "active" : true,
            "type" : [
              {
                "coding" : [
                  {
                    "system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-organization-type",
                    "code" : "analytical-testing-stability",
                    "display" : "Analytical Testing - Stability"
                  }
                ]
              }
            ],
            "name" : "Testing Lab"
          }
        },
        {
          "fullUrl" : "urn:uuid:a3fdc23b-6c16-2e65-481e-3fc895b37b87",
          "resource" : {
            "resourceType" : "Substance",
            "id" : "a3fdc23b-6c16-2e65-481e-3fc895b37b87",
            "text" : // actual-batch-substance
            {
              "status" : "extensions",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Substance_a3fdc23b-6c16-2e65-481e-3fc895b37b87\"> </a><p><b>Generated Narrative: Substance</b><a name=\"a3fdc23b-6c16-2e65-481e-3fc895b37b87\"> </a><a name=\"hca3fdc23b-6c16-2e65-481e-3fc895b37b87\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Substance &quot;a3fdc23b-6c16-2e65-481e-3fc895b37b87&quot; </p></div><blockquote><p><b>Medication Manufacturing Batch</b></p><blockquote><p><b>url</b></p><code>manufacturingDate</code></blockquote><p><b>value</b>: 2020-01</p><blockquote><p><b>url</b></p><code>batchQuantity</code></blockquote><p><b>value</b>: 120 kg</p><blockquote><p><b>url</b></p><code>batchUtilization</code></blockquote><p><b>value</b>: Production <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.0.0/CodeSystem-v3-nciThesaurus.html\">NCI Thesaurus</a>#C133990 &quot;Commercial&quot;)</span></p><blockquote><p><b>url</b></p><code>assignedManufacturer</code></blockquote><p><b>value</b>: See on this page: Organization/e2359a4e-3091-23f8-2242-87e701830d55</p><blockquote><p><b>url</b></p><code>container</code></blockquote></blockquote><p><b>Extension - Batch Release Date PQ</b>: 2019-09-08</p><p><b>Extension - Batch Retest Date PQ</b>: 2022-09-08</p><p><b>Extension - Actual Yield PQ</b>: 4.8 kg</p><p><b>identifier</b>: CAT1</p><p><b>instance</b>: true</p><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td>See on this page: SubstanceDefinition/2e3a85b5-790a-a108-3627-edf0ec6f1210</td></tr></table></div>"
            },
            "extension" : [
              {
                "url" : "http://hl7.org/fhir/StructureDefinition/medication-manufacturingBatch",
                "extension" : [
                  {
                    "url" : "manufacturingDate",
                    "valueDateTime" : "2020-01"
                  },
                  {
                    "url" : "batchQuantity",
                    "valueQuantity" : {
                      "value" : 120,
                      "unit" : "kg"
                    }
                  },
                  {
                    "url" : "batchUtilization",
                    "valueCodeableConcept" : {
                      "coding" : [
                        //  could also be C185328 Stability Study?
                        {
                          "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                          "code" : "C133990",
                          "display" : "Commercial"
                        }
                      ],
                      "text" : "Production"
                    }
                  },
                  {
                    "url" : "assignedManufacturer",
                    "valueReference" : {
                      "reference" : "Organization/e2359a4e-3091-23f8-2242-87e701830d55"
                    }
                  },
                  // Organization/substance-manufacturer
                  {
                    "url" : "container",
                    "extension" : [
                      {
                        "url" : "type",
                        "valueCodeableConcept" : {
                          "text" : "packaged in LDPE bags within HDPE drums"
                        }
                      }
                    ]
                  }
                ]
              },
              {
                "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-release-date-pq",
                "valueDateTime" : "2019-09-08"
              },
              {
                "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-retest-date-pq",
                "valueDateTime" : "2022-09-08"
              },
              {
                "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-pq",
                "valueQuantity" : {
                  "value" : 4.8,
                  "unit" : "kg"
                }
              }
            ],
            "identifier" : [
              {
                "value" : "CAT1"
              }
            ],
            "instance" : true,
            "code" : {
              "reference" : {
                "reference" : "SubstanceDefinition/2e3a85b5-790a-a108-3627-edf0ec6f1210"
              }
            }
          }
        },
        // SubstanceDefinition/substance1
        {
          "fullUrl" : "urn:uuid:cbcecab6-374c-396f-29be-877da7285e8d",
          "resource" : {
            "resourceType" : "Substance",
            "id" : "cbcecab6-374c-396f-29be-877da7285e8d",
            "text" : // actual-batch-substance-2
            {
              "status" : "extensions",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Substance_cbcecab6-374c-396f-29be-877da7285e8d\"> </a><p><b>Generated Narrative: Substance</b><a name=\"cbcecab6-374c-396f-29be-877da7285e8d\"> </a><a name=\"hccbcecab6-374c-396f-29be-877da7285e8d\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Substance &quot;cbcecab6-374c-396f-29be-877da7285e8d&quot; </p></div><blockquote><p><b>Medication Manufacturing Batch</b></p><blockquote><p><b>url</b></p><code>manufacturingDate</code></blockquote><p><b>value</b>: 2020-02</p><blockquote><p><b>url</b></p><code>batchQuantity</code></blockquote><p><b>value</b>: 120 kg</p><blockquote><p><b>url</b></p><code>batchUtilization</code></blockquote><p><b>value</b>: Production <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.0.0/CodeSystem-v3-nciThesaurus.html\">NCI Thesaurus</a>#C133990 &quot;Commercial&quot;)</span></p><blockquote><p><b>url</b></p><code>assignedManufacturer</code></blockquote><p><b>value</b>: See on this page: Organization/e2359a4e-3091-23f8-2242-87e701830d55</p></blockquote><p><b>Extension - Batch Release Date PQ</b>: 2019-09-08</p><p><b>Extension - Batch Retest Date PQ</b>: 2022-09-08</p><p><b>Extension - Actual Yield PQ</b>: 4.8 kg</p><p><b>identifier</b>: CAT2</p><p><b>instance</b>: true</p><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td>See on this page: SubstanceDefinition/2e3a85b5-790a-a108-3627-edf0ec6f1210</td></tr></table></div>"
            },
            "extension" : [
              {
                "url" : "http://hl7.org/fhir/StructureDefinition/medication-manufacturingBatch",
                "extension" : [
                  {
                    "url" : "manufacturingDate",
                    "valueDateTime" : "2020-02"
                  },
                  {
                    "url" : "batchQuantity",
                    "valueQuantity" : {
                      "value" : 120,
                      "unit" : "kg"
                    }
                  },
                  {
                    "url" : "batchUtilization",
                    "valueCodeableConcept" : {
                      "coding" : [
                        //  could also be C185328 Stability Study?
                        {
                          "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                          "code" : "C133990",
                          "display" : "Commercial"
                        }
                      ],
                      "text" : "Production"
                    }
                  },
                  {
                    "url" : "assignedManufacturer",
                    "valueReference" : {
                      "reference" : "Organization/e2359a4e-3091-23f8-2242-87e701830d55"
                    }
                  }
                ]
              },
              // Organization/substance-manufacturer
              {
                "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-release-date-pq",
                "valueDateTime" : "2019-09-08"
              },
              {
                "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-retest-date-pq",
                "valueDateTime" : "2022-09-08"
              },
              {
                "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-pq",
                "valueQuantity" : {
                  "value" : 4.8,
                  "unit" : "kg"
                }
              }
            ],
            "identifier" : [
              {
                "value" : "CAT2"
              }
            ],
            "instance" : true,
            "code" : {
              "reference" : {
                "reference" : "SubstanceDefinition/2e3a85b5-790a-a108-3627-edf0ec6f1210"
              }
            }
          }
        },
        // SubstanceDefinition/substance1
        {
          "fullUrl" : "urn:uuid:ae1f3b4c-4f14-1460-6903-7260959ea2cd",
          "resource" : {
            "resourceType" : "Substance",
            "id" : "ae1f3b4c-4f14-1460-6903-7260959ea2cd",
            "text" : // actual-batch-substance-3
            {
              "status" : "extensions",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Substance_ae1f3b4c-4f14-1460-6903-7260959ea2cd\"> </a><p><b>Generated Narrative: Substance</b><a name=\"ae1f3b4c-4f14-1460-6903-7260959ea2cd\"> </a><a name=\"hcae1f3b4c-4f14-1460-6903-7260959ea2cd\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Substance &quot;ae1f3b4c-4f14-1460-6903-7260959ea2cd&quot; </p></div><blockquote><p><b>Medication Manufacturing Batch</b></p><blockquote><p><b>url</b></p><code>manufacturingDate</code></blockquote><p><b>value</b>: 2020-03</p><blockquote><p><b>url</b></p><code>batchQuantity</code></blockquote><p><b>value</b>: 120 kg</p><blockquote><p><b>url</b></p><code>batchUtilization</code></blockquote><p><b>value</b>: Production <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.0.0/CodeSystem-v3-nciThesaurus.html\">NCI Thesaurus</a>#C133990 &quot;Commercial&quot;)</span></p><blockquote><p><b>url</b></p><code>assignedManufacturer</code></blockquote><p><b>value</b>: See on this page: Organization/e2359a4e-3091-23f8-2242-87e701830d55</p></blockquote><p><b>Extension - Batch Release Date PQ</b>: 2019-09-08</p><p><b>Extension - Batch Retest Date PQ</b>: 2022-09-08</p><p><b>Extension - Actual Yield PQ</b>: 4.8 kg</p><p><b>identifier</b>: CAT3</p><p><b>instance</b>: true</p><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td>See on this page: SubstanceDefinition/2e3a85b5-790a-a108-3627-edf0ec6f1210</td></tr></table></div>"
            },
            "extension" : [
              {
                "url" : "http://hl7.org/fhir/StructureDefinition/medication-manufacturingBatch",
                "extension" : [
                  {
                    "url" : "manufacturingDate",
                    "valueDateTime" : "2020-03"
                  },
                  {
                    "url" : "batchQuantity",
                    "valueQuantity" : {
                      "value" : 120,
                      "unit" : "kg"
                    }
                  },
                  {
                    "url" : "batchUtilization",
                    "valueCodeableConcept" : {
                      "coding" : [
                        //  could also be C185328 Stability Study?
                        {
                          "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                          "code" : "C133990",
                          "display" : "Commercial"
                        }
                      ],
                      "text" : "Production"
                    }
                  },
                  {
                    "url" : "assignedManufacturer",
                    "valueReference" : {
                      "reference" : "Organization/e2359a4e-3091-23f8-2242-87e701830d55"
                    }
                  }
                ]
              },
              // Organization/substance-manufacturer
              {
                "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-release-date-pq",
                "valueDateTime" : "2019-09-08"
              },
              {
                "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-retest-date-pq",
                "valueDateTime" : "2022-09-08"
              },
              {
                "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-pq",
                "valueQuantity" : {
                  "value" : 4.8,
                  "unit" : "kg"
                }
              }
            ],
            "identifier" : [
              {
                "value" : "CAT3"
              }
            ],
            "instance" : true,
            "code" : {
              "reference" : {
                "reference" : "SubstanceDefinition/2e3a85b5-790a-a108-3627-edf0ec6f1210"
              }
            }
          }
        }
      ]
    }