Pharmaceutical Quality (Industry)
1.0.0 - STU1

Pharmaceutical Quality (Industry), published by HL7 International / Biomedical Research and Regulation. This guide is not an authorized publication; it is the continuous build for version 1.0.0 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/uv-dx-pq/ and changes regularly. See the Directory of published versions

## : Example: Bundle – Substance Specification - TTL Representation

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    @prefix fhir: <http://hl7.org/fhir/> .
    @prefix owl: <http://www.w3.org/2002/07/owl#> .
    @prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
    @prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

    # - resource -------------------------------------------------------------------

    #  Substance Specification

     a fhir:Bundle ;
      fhir:nodeRole fhir:treeRoot ;
      fhir:id [ fhir:v "bundle-drug-substance-specification-pq-ex1"] ; #
      fhir:meta [
        ( fhir:profile [
    fhir:v "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Bundle-drug-substance-specification-pq"^^xsd:anyURI ;
    fhir:link <http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Bundle-drug-substance-specification-pq>     ] )
      ] ; #
      fhir:type [ fhir:v "collection"] ; #
      fhir:entry ( [
    fhir:fullUrl [ fhir:v "urn:uuid:bf6b038b-1334-3dd4-a552-65c169e2265a"^^xsd:anyURI ] ;
        ( fhir:resource <urn:uuid:bf6b038b-1334-3dd4-a552-65c169e2265a> )
      ] [
    fhir:fullUrl [ fhir:v "urn:uuid:52176085-1f30-0c67-9ad7-523c486c82c9"^^xsd:anyURI ] ;
        ( fhir:resource <urn:uuid:52176085-1f30-0c67-9ad7-523c486c82c9> )
      ] [
    fhir:fullUrl [ fhir:v "urn:uuid:b50d892c-8980-0774-39d4-d449732873a3"^^xsd:anyURI ] ;
        ( fhir:resource <urn:uuid:b50d892c-8980-0774-39d4-d449732873a3> )
      ] [
    fhir:fullUrl [ fhir:v "urn:uuid:d460b561-110c-7eb6-5d69-788abcca391a"^^xsd:anyURI ] ;
        ( fhir:resource <urn:uuid:d460b561-110c-7eb6-5d69-788abcca391a> )
      ] [
    fhir:fullUrl [ fhir:v "urn:uuid:006a9f7b-91ca-5601-38ef-a3dd26ad7121"^^xsd:anyURI ] ;
        ( fhir:resource <urn:uuid:006a9f7b-91ca-5601-38ef-a3dd26ad7121> )
      ] [
    fhir:fullUrl [ fhir:v "urn:uuid:c59deb1b-835c-1be5-4e08-95dea3ae1a17"^^xsd:anyURI ] ;
        ( fhir:resource <urn:uuid:c59deb1b-835c-1be5-4e08-95dea3ae1a17> )
      ] [
    fhir:fullUrl [ fhir:v "urn:uuid:18e20bae-1a24-202d-11d7-5f354c785e4d"^^xsd:anyURI ] ;
        ( fhir:resource <urn:uuid:18e20bae-1a24-202d-11d7-5f354c785e4d> )
      ] [
    fhir:fullUrl [ fhir:v "urn:uuid:22544fa4-0fa2-1d5a-253d-a1fbe8fd61ce"^^xsd:anyURI ] ;
        ( fhir:resource <urn:uuid:22544fa4-0fa2-1d5a-253d-a1fbe8fd61ce> )
      ] [
    fhir:fullUrl [ fhir:v "urn:uuid:b4f736ff-1bbf-6923-4d5c-85d262285d7d"^^xsd:anyURI ] ;
        ( fhir:resource <urn:uuid:b4f736ff-1bbf-6923-4d5c-85d262285d7d> )
      ] [
    fhir:fullUrl [ fhir:v "urn:uuid:233865df-2a71-528d-756c-85f36bd6685f"^^xsd:anyURI ] ;
        ( fhir:resource <urn:uuid:233865df-2a71-528d-756c-85f36bd6685f> )
      ] [
    fhir:fullUrl [ fhir:v "urn:uuid:03d68d1c-162c-8b6e-70f9-647b0ea97adb"^^xsd:anyURI ] ;
        ( fhir:resource <urn:uuid:03d68d1c-162c-8b6e-70f9-647b0ea97adb> )
      ] [
    fhir:fullUrl [ fhir:v "urn:uuid:062bf235-44e2-55c4-9213-bbe5e12d5620"^^xsd:anyURI ] ;
        ( fhir:resource <urn:uuid:062bf235-44e2-55c4-9213-bbe5e12d5620> )
      ] ) . #

    <urn:uuid:bf6b038b-1334-3dd4-a552-65c169e2265a> a fhir:PlanDefinition ;
      fhir:id [ fhir:v "specificationProtocol"] ; #
      fhir:text [
    fhir:status [ fhir:v "generated" ] ;
    fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"PlanDefinition_specificationProtocol\"> </a><p><b>Generated Narrative: PlanDefinition</b><a name=\"specificationProtocol\"> </a><a name=\"hcspecificationProtocol\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource PlanDefinition &quot;specificationProtocol&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/PlanDefinition/bf6b038b-1334-3dd4-a552-65c169e2265a</code></p><p><b>title</b>: SPECIFICATION FOR DRUG SUBSTANCE</p><p><b>status</b>: active</p><p><b>subject</b>: See on this page: SubstanceDefinition/03d68d1c-162c-8b6e-70f9-647b0ea97adb</p><p><b>description</b>: Narrative description of specifications</p><blockquote><p><b>action</b></p><p><b>title</b>: Specification for Drug Substance</p><p><b>code</b>: Overall set of actions <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>Actions</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Definition[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Test <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/52176085-1f30-0c67-9ad7-523c486c82c9\">http://example-server.com/fhir/ObservationDefinition/52176085-1f30-0c67-9ad7-523c486c82c9</a></td></tr><tr><td style=\"display: none\">*</td><td>Test <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/b50d892c-8980-0774-39d4-d449732873a3\">http://example-server.com/fhir/ObservationDefinition/b50d892c-8980-0774-39d4-d449732873a3</a></td></tr><tr><td style=\"display: none\">*</td><td>Test <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/d460b561-110c-7eb6-5d69-788abcca391a\">http://example-server.com/fhir/ObservationDefinition/d460b561-110c-7eb6-5d69-788abcca391a</a></td></tr><tr><td style=\"display: none\">*</td><td>Test <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/006a9f7b-91ca-5601-38ef-a3dd26ad7121\">http://example-server.com/fhir/ObservationDefinition/006a9f7b-91ca-5601-38ef-a3dd26ad7121</a></td></tr><tr><td style=\"display: none\">*</td><td>Test <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/c59deb1b-835c-1be5-4e08-95dea3ae1a17\">http://example-server.com/fhir/ObservationDefinition/c59deb1b-835c-1be5-4e08-95dea3ae1a17</a></td></tr><tr><td style=\"display: none\">*</td><td>Test <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/18e20bae-1a24-202d-11d7-5f354c785e4d\">http://example-server.com/fhir/ObservationDefinition/18e20bae-1a24-202d-11d7-5f354c785e4d</a></td></tr><tr><td style=\"display: none\">*</td><td>Test <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/22544fa4-0fa2-1d5a-253d-a1fbe8fd61ce\">http://example-server.com/fhir/ObservationDefinition/22544fa4-0fa2-1d5a-253d-a1fbe8fd61ce</a></td></tr><tr><td style=\"display: none\">*</td><td>Test <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/b4f736ff-1bbf-6923-4d5c-85d262285d7d\">http://example-server.com/fhir/ObservationDefinition/b4f736ff-1bbf-6923-4d5c-85d262285d7d</a></td></tr><tr><td style=\"display: none\">*</td><td>Test <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/233865df-2a71-528d-756c-85f36bd6685f\">http://example-server.com/fhir/ObservationDefinition/233865df-2a71-528d-756c-85f36bd6685f</a></td></tr></table></blockquote></div>"
      ] ; #
      fhir:url [ fhir:v "http://example-server.com/fhir/PlanDefinition/bf6b038b-1334-3dd4-a552-65c169e2265a"^^xsd:anyURI] ; # http://example-server.com/fhir/PlanDefinition/bf6b038b-1334-3dd4-a552-65c169e2265a
      fhir:title [ fhir:v "SPECIFICATION FOR DRUG SUBSTANCE"] ; #
      fhir:status [ fhir:v "active"] ; #
      fhir:subject [
    a fhir:Reference ;
    fhir:reference [ fhir:v "SubstanceDefinition/03d68d1c-162c-8b6e-70f9-647b0ea97adb" ] # SubstanceDefinition\/substance1
      ] ; #
      fhir:description [ fhir:v "Narrative description of specifications"] ; #
      fhir:action ( [
    fhir:title [ fhir:v "Specification for Drug Substance" ] ; #  this is then entire thing
    fhir:code [
    fhir:text [ fhir:v "Overall set of actions" ]     ] ;
        ( fhir:action [
    fhir:code [
    fhir:text [ fhir:v "Test" ]       ] ;
    fhir:definition [
    fhir:v "http://example-server.com/fhir/ObservationDefinition/52176085-1f30-0c67-9ad7-523c486c82c9"^^xsd:anyURI ;
    fhir:link <http://example-server.com/fhir/ObservationDefinition/52176085-1f30-0c67-9ad7-523c486c82c9>       ] # ObservationDefinition\/Description     ] [
    fhir:code [
    fhir:text [ fhir:v "Test" ]       ] ;
    fhir:definition [
    fhir:v "http://example-server.com/fhir/ObservationDefinition/b50d892c-8980-0774-39d4-d449732873a3"^^xsd:anyURI ;
    fhir:link <http://example-server.com/fhir/ObservationDefinition/b50d892c-8980-0774-39d4-d449732873a3>       ] # ObservationDefinition\/Identification     ] [
    fhir:code [
    fhir:text [ fhir:v "Test" ]       ] ;
    fhir:definition [
    fhir:v "http://example-server.com/fhir/ObservationDefinition/d460b561-110c-7eb6-5d69-788abcca391a"^^xsd:anyURI ;
    fhir:link <http://example-server.com/fhir/ObservationDefinition/d460b561-110c-7eb6-5d69-788abcca391a>       ] # ObservationDefinition\/Assay     ] [
    fhir:code [
    fhir:text [ fhir:v "Test" ]       ] ;
    fhir:definition [
    fhir:v "http://example-server.com/fhir/ObservationDefinition/006a9f7b-91ca-5601-38ef-a3dd26ad7121"^^xsd:anyURI ;
    fhir:link <http://example-server.com/fhir/ObservationDefinition/006a9f7b-91ca-5601-38ef-a3dd26ad7121>       ] # ObservationDefinition\/Impurities     ] [
    fhir:code [
    fhir:text [ fhir:v "Test" ]       ] ;
    fhir:definition [
    fhir:v "http://example-server.com/fhir/ObservationDefinition/c59deb1b-835c-1be5-4e08-95dea3ae1a17"^^xsd:anyURI ;
    fhir:link <http://example-server.com/fhir/ObservationDefinition/c59deb1b-835c-1be5-4e08-95dea3ae1a17>       ] # ObservationDefinition\/Mutagenic     ] [
    fhir:code [
    fhir:text [ fhir:v "Test" ]       ] ;
    fhir:definition [
    fhir:v "http://example-server.com/fhir/ObservationDefinition/18e20bae-1a24-202d-11d7-5f354c785e4d"^^xsd:anyURI ;
    fhir:link <http://example-server.com/fhir/ObservationDefinition/18e20bae-1a24-202d-11d7-5f354c785e4d>       ] # ObservationDefinition\/Enantiomeric     ] [
    fhir:code [
    fhir:text [ fhir:v "Test" ]       ] ;
    fhir:definition [
    fhir:v "http://example-server.com/fhir/ObservationDefinition/22544fa4-0fa2-1d5a-253d-a1fbe8fd61ce"^^xsd:anyURI ;
    fhir:link <http://example-server.com/fhir/ObservationDefinition/22544fa4-0fa2-1d5a-253d-a1fbe8fd61ce>       ] # ObservationDefinition\/Solvents     ] [
    fhir:code [
    fhir:text [ fhir:v "Test" ]       ] ;
    fhir:definition [
    fhir:v "http://example-server.com/fhir/ObservationDefinition/b4f736ff-1bbf-6923-4d5c-85d262285d7d"^^xsd:anyURI ;
    fhir:link <http://example-server.com/fhir/ObservationDefinition/b4f736ff-1bbf-6923-4d5c-85d262285d7d>       ] # ObservationDefinition\/Water     ] [
    fhir:code [
    fhir:text [ fhir:v "Test" ]       ] ;
    fhir:definition [
    fhir:v "http://example-server.com/fhir/ObservationDefinition/233865df-2a71-528d-756c-85f36bd6685f"^^xsd:anyURI ;
    fhir:link <http://example-server.com/fhir/ObservationDefinition/233865df-2a71-528d-756c-85f36bd6685f>       ] # ObservationDefinition\/Particles     ] )
      ] ) . #

    <urn:uuid:52176085-1f30-0c67-9ad7-523c486c82c9> a fhir:ObservationDefinition ;
      fhir:id [ fhir:v "52176085-1f30-0c67-9ad7-523c486c82c9"] ; # Description
      fhir:text [
    fhir:status [ fhir:v "generated" ] ;
    fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_52176085-1f30-0c67-9ad7-523c486c82c9\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"52176085-1f30-0c67-9ad7-523c486c82c9\"> </a><a name=\"hc52176085-1f30-0c67-9ad7-523c486c82c9\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;52176085-1f30-0c67-9ad7-523c486c82c9&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/52176085-1f30-0c67-9ad7-523c486c82c9</code></p><p><b>title</b>: Description</p><p><b>status</b>: active</p><p><b>code</b>: Description <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DESC)</span></p><p><b>method</b>: Visual inspection <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td></tr><tr><td style=\"display: none\">*</td><td/></tr></table></div>"
      ] ; #
      fhir:url [ fhir:v "http://example-server.com/fhir/ObservationDefinition/52176085-1f30-0c67-9ad7-523c486c82c9"^^xsd:anyURI] ; # http://example-server.com/fhir/ObservationDefinition/52176085-1f30-0c67-9ad7-523c486c82c9
      fhir:title [ fhir:v "Description"] ; #
      fhir:status [ fhir:v "active"] ; #
      fhir:code [
        ( fhir:coding [
    fhir:system [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "DESC" ] ;
    fhir:display [ fhir:v "Description" ]     ] ) ;
    fhir:text [ fhir:v "Description" ]
      ] ; #
      fhir:method [
    fhir:text [ fhir:v "Visual inspection" ]
      ] ; #
      fhir:qualifiedValue ( [
        ( fhir:extension [
    fhir:url [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-text-pq"^^xsd:anyURI ] ;
    fhir:value [ fhir:v "A white to brown powder" ]     ] )
      ] ) . #

    <urn:uuid:b50d892c-8980-0774-39d4-d449732873a3> a fhir:ObservationDefinition ;
      fhir:id [ fhir:v "b50d892c-8980-0774-39d4-d449732873a3"] ; # Identification
      fhir:text [
    fhir:status [ fhir:v "generated" ] ;
    fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_b50d892c-8980-0774-39d4-d449732873a3\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"b50d892c-8980-0774-39d4-d449732873a3\"> </a><a name=\"hcb50d892c-8980-0774-39d4-d449732873a3\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;b50d892c-8980-0774-39d4-d449732873a3&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/b50d892c-8980-0774-39d4-d449732873a3</code></p><p><b>title</b>: Identification</p><p><b>status</b>: active</p><p><b>code</b>: Identification <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IDT)</span></p><p><b>method</b>: Identification by IR spectroscopy Identification by HPLC <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td></tr><tr><td style=\"display: none\">*</td><td/></tr></table></div>"
      ] ; #
      fhir:url [ fhir:v "http://example-server.com/fhir/ObservationDefinition/b50d892c-8980-0774-39d4-d449732873a3"^^xsd:anyURI] ; # http://example-server.com/fhir/ObservationDefinition/b50d892c-8980-0774-39d4-d449732873a3
      fhir:title [ fhir:v "Identification"] ; #
      fhir:status [ fhir:v "active"] ; #
      fhir:code [
        ( fhir:coding [
    fhir:system [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "IDT" ] ;
    fhir:display [ fhir:v "Identification" ]     ] ) ;
    fhir:text [ fhir:v "Identification" ]
      ] ; #
      fhir:method [
    fhir:text [ fhir:v "Identification by IR spectroscopy Identification by HPLC" ]
      ] ; #
      fhir:qualifiedValue ( [
        ( fhir:extension [
    fhir:url [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-text-pq"^^xsd:anyURI ] ;
    fhir:value [ fhir:v "Conforms with reference" ]     ] )
      ] ) . #

    <urn:uuid:d460b561-110c-7eb6-5d69-788abcca391a> a fhir:ObservationDefinition ;
      fhir:id [ fhir:v "d460b561-110c-7eb6-5d69-788abcca391a"] ; # Assay
      fhir:text [
    fhir:status [ fhir:v "generated" ] ;
    fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_d460b561-110c-7eb6-5d69-788abcca391a\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"d460b561-110c-7eb6-5d69-788abcca391a\"> </a><a name=\"hcd460b561-110c-7eb6-5d69-788abcca391a\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;d460b561-110c-7eb6-5d69-788abcca391a&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/d460b561-110c-7eb6-5d69-788abcca391a</code></p><p><b>title</b>: Assay</p><p><b>status</b>: active</p><p><b>code</b>: Assay <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#ASSAY)</span></p><p><b>method</b>: Assay by LC <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>98-102 % w/w</td></tr></table></div>"
      ] ; #
      fhir:url [ fhir:v "http://example-server.com/fhir/ObservationDefinition/d460b561-110c-7eb6-5d69-788abcca391a"^^xsd:anyURI] ; # http://example-server.com/fhir/ObservationDefinition/d460b561-110c-7eb6-5d69-788abcca391a
      fhir:title [ fhir:v "Assay"] ; #
      fhir:status [ fhir:v "active"] ; #
      fhir:code [
        ( fhir:coding [
    fhir:system [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "ASSAY" ] ;
    fhir:display [ fhir:v "Assay" ]     ] ) ;
    fhir:text [ fhir:v "Assay" ]
      ] ; #
      fhir:method [
    fhir:text [ fhir:v "Assay by LC" ]
      ] ; #
      fhir:qualifiedValue ( [
    fhir:range [
    fhir:low [
    fhir:value [ fhir:v "98"^^xsd:decimal ] ;
    fhir:unit [ fhir:v "% w/w" ] ;
    fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "%" ]       ] ;
    fhir:high [
    fhir:value [ fhir:v "102"^^xsd:decimal ] ;
    fhir:unit [ fhir:v "% w/w" ] ;
    fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "%" ]       ]     ]
      ] ) . #

    <urn:uuid:006a9f7b-91ca-5601-38ef-a3dd26ad7121> a fhir:ObservationDefinition ;
      fhir:id [ fhir:v "006a9f7b-91ca-5601-38ef-a3dd26ad7121"] ; # Impurities
      fhir:text [
    fhir:status [ fhir:v "generated" ] ;
    fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_006a9f7b-91ca-5601-38ef-a3dd26ad7121\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"006a9f7b-91ca-5601-38ef-a3dd26ad7121\"> </a><a name=\"hc006a9f7b-91ca-5601-38ef-a3dd26ad7121\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;006a9f7b-91ca-5601-38ef-a3dd26ad7121&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/006a9f7b-91ca-5601-38ef-a3dd26ad7121</code></p><p><b>title</b>: Drug Substance Related Organic impurities</p><p><b>status</b>: active</p><p><b>code</b>: Drug Substance Related Organic impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#DGP-s)</span></p><p><b>method</b>: Organic impurities by LC <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: Impurity 1 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>range</b>: ?-0.5</p></blockquote><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: Impurity 2 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>range</b>: ?-0.5</p></blockquote><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: Any individual unspecified impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>range</b>: ?-0.10</p></blockquote><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: Total impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>range</b>: ?-2.0</p></blockquote><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td></tr></table></div>"
      ] ; #
      fhir:url [ fhir:v "http://example-server.com/fhir/ObservationDefinition/006a9f7b-91ca-5601-38ef-a3dd26ad7121"^^xsd:anyURI] ; # http://example-server.com/fhir/ObservationDefinition/006a9f7b-91ca-5601-38ef-a3dd26ad7121
      fhir:title [ fhir:v "Drug Substance Related Organic impurities"] ; #
      fhir:status [ fhir:v "active"] ; #
      fhir:code [
        ( fhir:coding [
    fhir:system [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "DGP-s" ] ;
    fhir:display [ fhir:v "Drug Substance Related Organic impurities" ]     ] )
      ] ; #
      fhir:method [
    fhir:text [ fhir:v "Organic impurities by LC" ]
      ] ; #
      fhir:qualifiedValue ( [
        ( fhir:appliesTo [
    fhir:text [ fhir:v "Impurity 1" ] #  could be a code      ] ) ;
    fhir:range [
    fhir:high [
    fhir:value [ fhir:v "0.5"^^xsd:decimal ] ;
    fhir:unit [ fhir:v "% w/w" ]       ]     ]
      ] [
        ( fhir:appliesTo [
    fhir:text [ fhir:v "Impurity 2" ]     ] ) ;
    fhir:range [
    fhir:high [
    fhir:value [ fhir:v "0.5"^^xsd:decimal ] ;
    fhir:unit [ fhir:v "% w/w" ]       ]     ]
      ] [
        ( fhir:appliesTo [
    fhir:text [ fhir:v "Any individual unspecified impurity" ]     ] ) ;
    fhir:range [
    fhir:high [
    fhir:value [ fhir:v "0.10"^^xsd:decimal ] ;
    fhir:unit [ fhir:v "% w/w" ]       ]     ]
      ] [
        ( fhir:appliesTo [
    fhir:text [ fhir:v "Total impurities" ]     ] ) ;
    fhir:range [
    fhir:high [
    fhir:value [ fhir:v "2.0"^^xsd:decimal ] ;
    fhir:unit [ fhir:v "% w/w" ]       ]     ]
      ] ) ; #
      fhir:component ( [
    fhir:code [
          ( fhir:coding [
    fhir:system [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "IMP" ] ;
    fhir:display [ fhir:v "Impurity" ]       ] )     ] #  are expected to have a component that says what impurity this one is
      ] ) . #

    <urn:uuid:c59deb1b-835c-1be5-4e08-95dea3ae1a17> a fhir:ObservationDefinition ;
      fhir:id [ fhir:v "c59deb1b-835c-1be5-4e08-95dea3ae1a17"] ; # Mutagenic
      fhir:text [
    fhir:status [ fhir:v "generated" ] ;
    fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_c59deb1b-835c-1be5-4e08-95dea3ae1a17\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"c59deb1b-835c-1be5-4e08-95dea3ae1a17\"> </a><a name=\"hcc59deb1b-835c-1be5-4e08-95dea3ae1a17\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;c59deb1b-835c-1be5-4e08-95dea3ae1a17&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/c59deb1b-835c-1be5-4e08-95dea3ae1a17</code></p><p><b>title</b>: Mutagenic impurities</p><p><b>status</b>: active</p><p><b>code</b>: Mutagenic impurities <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#MUT)</span></p><p><b>method</b>: Impurity 5 content by LC-MS <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>AppliesTo</b></td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity - Mutagenic <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td>?-50</td></tr></table><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#IMP)</span></td></tr></table></div>"
      ] ; #
      fhir:url [ fhir:v "http://example-server.com/fhir/ObservationDefinition/c59deb1b-835c-1be5-4e08-95dea3ae1a17"^^xsd:anyURI] ; # http://example-server.com/fhir/ObservationDefinition/c59deb1b-835c-1be5-4e08-95dea3ae1a17
      fhir:title [ fhir:v "Mutagenic impurities"] ; #
      fhir:status [ fhir:v "active"] ; #
      fhir:code [
        ( fhir:coding [
    fhir:system [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "MUT" ] ;
    fhir:display [ fhir:v "Mutagenic impurities" ]     ] )
      ] ; #
      fhir:method [
    fhir:text [ fhir:v "Impurity 5 content by LC-MS" ]
      ] ; #
      fhir:qualifiedValue ( [
        ( fhir:appliesTo [
    fhir:text [ fhir:v "Impurity - Mutagenic" ] #  could be a code      ] ) ;
    fhir:range [
    fhir:high [
    fhir:value [ fhir:v "50"^^xsd:decimal ] ;
    fhir:unit [ fhir:v "ppm" ] ;
    fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "[ppm]" ]       ]     ]
      ] ) ; #
      fhir:component ( [
    fhir:code [
          ( fhir:coding [
    fhir:system [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "IMP" ] ;
    fhir:display [ fhir:v "Impurity" ]       ] )     ] #  are expected to have a component that says what impurity this one is
      ] ) . #

    <urn:uuid:18e20bae-1a24-202d-11d7-5f354c785e4d> a fhir:ObservationDefinition ;
      fhir:id [ fhir:v "18e20bae-1a24-202d-11d7-5f354c785e4d"] ; # Enantiomeric
      fhir:text [
    fhir:status [ fhir:v "generated" ] ;
    fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_18e20bae-1a24-202d-11d7-5f354c785e4d\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"18e20bae-1a24-202d-11d7-5f354c785e4d\"> </a><a name=\"hc18e20bae-1a24-202d-11d7-5f354c785e4d\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;18e20bae-1a24-202d-11d7-5f354c785e4d&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/18e20bae-1a24-202d-11d7-5f354c785e4d</code></p><p><b>title</b>: Enantiomeric purity</p><p><b>status</b>: active</p><p><b>code</b>: Enantiomeric purity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#enantiomeric-purity)</span></p><p><b>method</b>: Enantiomeric purity by LC <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>99.6-? %</td></tr></table></div>"
      ] ; #
      fhir:url [ fhir:v "http://example-server.com/fhir/ObservationDefinition/18e20bae-1a24-202d-11d7-5f354c785e4d"^^xsd:anyURI] ; # http://example-server.com/fhir/ObservationDefinition/18e20bae-1a24-202d-11d7-5f354c785e4d
      fhir:title [ fhir:v "Enantiomeric purity"] ; #
      fhir:status [ fhir:v "active"] ; #
      fhir:code [
        ( fhir:coding [
    fhir:system [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "enantiomeric-purity" ] ;
    fhir:display [ fhir:v "Enantiomeric purity" ]     ] ) ;
    fhir:text [ fhir:v "Enantiomeric purity" ]
      ] ; #
      fhir:method [
    fhir:text [ fhir:v "Enantiomeric purity by LC" ]
      ] ; #
      fhir:qualifiedValue ( [
    fhir:range [
    fhir:low [
    fhir:value [ fhir:v "99.6"^^xsd:decimal ] ;
    fhir:unit [ fhir:v "%" ] ;
    fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "%" ]       ]     ]
      ] ) . #

    <urn:uuid:22544fa4-0fa2-1d5a-253d-a1fbe8fd61ce> a fhir:ObservationDefinition ;
      fhir:id [ fhir:v "22544fa4-0fa2-1d5a-253d-a1fbe8fd61ce"] ; # Solvents
      fhir:text [
    fhir:status [ fhir:v "generated" ] ;
    fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_22544fa4-0fa2-1d5a-253d-a1fbe8fd61ce\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"22544fa4-0fa2-1d5a-253d-a1fbe8fd61ce\"> </a><a name=\"hc22544fa4-0fa2-1d5a-253d-a1fbe8fd61ce\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;22544fa4-0fa2-1d5a-253d-a1fbe8fd61ce&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/22544fa4-0fa2-1d5a-253d-a1fbe8fd61ce</code></p><p><b>title</b>: Residual solvents</p><p><b>status</b>: active</p><p><b>code</b>: Residual solvents <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SOL)</span></p><p><b>method</b>: Residual solvents by headspace GC <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: Solvent 1 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>range</b>: ?-0.1</p></blockquote><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: Solvent 2 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>range</b>: ?-2.0</p></blockquote><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td></tr><tr><td style=\"display: none\">*</td><td>Solvent <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SOLV)</span></td></tr></table></div>"
      ] ; #
      fhir:url [ fhir:v "http://example-server.com/fhir/ObservationDefinition/22544fa4-0fa2-1d5a-253d-a1fbe8fd61ce"^^xsd:anyURI] ; # http://example-server.com/fhir/ObservationDefinition/22544fa4-0fa2-1d5a-253d-a1fbe8fd61ce
      fhir:title [ fhir:v "Residual solvents"] ; #
      fhir:status [ fhir:v "active"] ; #
      fhir:code [
        ( fhir:coding [
    fhir:system [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "SOL" ] ;
    fhir:display [ fhir:v "Residual solvents" ]     ] )
      ] ; #
      fhir:method [
    fhir:text [ fhir:v "Residual solvents by headspace GC" ]
      ] ; #
      fhir:qualifiedValue ( [
        ( fhir:appliesTo [
    fhir:text [ fhir:v "Solvent 1" ] #  could be a code      ] ) ;
    fhir:range [
    fhir:high [
    fhir:value [ fhir:v "0.1"^^xsd:decimal ] ;
    fhir:unit [ fhir:v "% w/w" ]       ]     ]
      ] [
        ( fhir:appliesTo [
    fhir:text [ fhir:v "Solvent 2" ]     ] ) ;
    fhir:range [
    fhir:high [
    fhir:value [ fhir:v "2.0"^^xsd:decimal ] ;
    fhir:unit [ fhir:v "% w/w" ]       ]     ]
      ] ) ; #
      fhir:component ( [
    fhir:code [
          ( fhir:coding [
    fhir:system [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "SOLV" ] ;
    fhir:display [ fhir:v "Solvent" ]       ] )     ] #  are expected to have a component that says what solvent this one is
      ] ) . #

    <urn:uuid:b4f736ff-1bbf-6923-4d5c-85d262285d7d> a fhir:ObservationDefinition ;
      fhir:id [ fhir:v "b4f736ff-1bbf-6923-4d5c-85d262285d7d"] ; # Water
      fhir:text [
    fhir:status [ fhir:v "generated" ] ;
    fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_b4f736ff-1bbf-6923-4d5c-85d262285d7d\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"b4f736ff-1bbf-6923-4d5c-85d262285d7d\"> </a><a name=\"hcb4f736ff-1bbf-6923-4d5c-85d262285d7d\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;b4f736ff-1bbf-6923-4d5c-85d262285d7d&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/b4f736ff-1bbf-6923-4d5c-85d262285d7d</code></p><p><b>title</b>: Water Content</p><p><b>status</b>: active</p><p><b>code</b>: Water Content <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#WaterContent)</span></p><p><b>method</b>: USP Karl Fischer titration <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>?-1.0</td></tr></table></div>"
      ] ; #
      fhir:url [ fhir:v "http://example-server.com/fhir/ObservationDefinition/b4f736ff-1bbf-6923-4d5c-85d262285d7d"^^xsd:anyURI] ; # http://example-server.com/fhir/ObservationDefinition/b4f736ff-1bbf-6923-4d5c-85d262285d7d
      fhir:title [ fhir:v "Water Content"] ; #
      fhir:status [ fhir:v "active"] ; #
      fhir:code [
        ( fhir:coding [
    fhir:system [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "WaterContent" ] ;
    fhir:display [ fhir:v "Water Content" ]     ] ) ;
    fhir:text [ fhir:v "Water Content" ]
      ] ; #
      fhir:method [
    fhir:text [ fhir:v "USP Karl Fischer titration" ]
      ] ; #
      fhir:qualifiedValue ( [
    fhir:range [
    fhir:high [
    fhir:value [ fhir:v "1.0"^^xsd:decimal ] ;
    fhir:unit [ fhir:v "% w/w" ]       ]     ]
      ] ) . #

    <urn:uuid:233865df-2a71-528d-756c-85f36bd6685f> a fhir:ObservationDefinition ;
      fhir:id [ fhir:v "233865df-2a71-528d-756c-85f36bd6685f"] ; # Particles
      fhir:text [
    fhir:status [ fhir:v "generated" ] ;
    fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_233865df-2a71-528d-756c-85f36bd6685f\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"233865df-2a71-528d-756c-85f36bd6685f\"> </a><a name=\"hc233865df-2a71-528d-756c-85f36bd6685f\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;233865df-2a71-528d-756c-85f36bd6685f&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/233865df-2a71-528d-756c-85f36bd6685f</code></p><p><b>title</b>: Particle size distribution</p><p><b>status</b>: active</p><p><b>code</b>: Particle size distribution <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#particle-size-distribution)</span></p><p><b>method</b>: Laser diffraction <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: D(v,0.9) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>range</b>: ?-319</p></blockquote><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: D(v,0.5) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>range</b>: ?-145</p></blockquote><blockquote><p><b>qualifiedValue</b></p><p><b>appliesTo</b>: D(v,0.1) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>range</b>: ?-20</p></blockquote><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td></tr><tr><td style=\"display: none\">*</td><td>Particle size <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#particle-size)</span></td></tr></table></div>"
      ] ; #
      fhir:url [ fhir:v "http://example-server.com/fhir/ObservationDefinition/233865df-2a71-528d-756c-85f36bd6685f"^^xsd:anyURI] ; # http://example-server.com/fhir/ObservationDefinition/233865df-2a71-528d-756c-85f36bd6685f
      fhir:title [ fhir:v "Particle size distribution"] ; #
      fhir:status [ fhir:v "active"] ; #
      fhir:code [
        ( fhir:coding [
    fhir:system [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "particle-size-distribution" ] ;
    fhir:display [ fhir:v "Particle size distribution" ]     ] )
      ] ; #
      fhir:method [
    fhir:text [ fhir:v "Laser diffraction" ]
      ] ; #
      fhir:qualifiedValue ( [
        ( fhir:appliesTo [
    fhir:text [ fhir:v "D(v,0.9)" ] #  could be a code      ] ) ;
    fhir:range [
    fhir:high [
    fhir:value [ fhir:v "319"^^xsd:decimal ] ;
    fhir:unit [ fhir:v "µm" ] ;
    fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "um" ]       ]     ]
      ] [
        ( fhir:appliesTo [
    fhir:text [ fhir:v "D(v,0.5)" ] #  could be a code      ] ) ;
    fhir:range [
    fhir:high [
    fhir:value [ fhir:v "145"^^xsd:decimal ] ;
    fhir:unit [ fhir:v "µm" ] ;
    fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "um" ]       ]     ]
      ] [
        ( fhir:appliesTo [
    fhir:text [ fhir:v "D(v,0.1)" ] #  could be a code      ] ) ;
    fhir:range [
    fhir:high [
    fhir:value [ fhir:v "20"^^xsd:decimal ] ;
    fhir:unit [ fhir:v "µm" ] ;
    fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "um" ]       ]     ]
      ] ) ; #
      fhir:component ( [
    fhir:code [
          ( fhir:coding [
    fhir:system [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "particle-size" ] ;
    fhir:display [ fhir:v "Particle size" ]       ] )     ] #  are expected to have a component that says what solvent this one is
      ] ) . #

    <urn:uuid:03d68d1c-162c-8b6e-70f9-647b0ea97adb> a fhir:SubstanceDefinition ;
      fhir:id [ fhir:v "03d68d1c-162c-8b6e-70f9-647b0ea97adb"] ; # substance1
      fhir:text [
    fhir:status [ fhir:v "generated" ] ;
    fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"SubstanceDefinition_03d68d1c-162c-8b6e-70f9-647b0ea97adb\"> </a><p><b>Generated Narrative: SubstanceDefinition</b><a name=\"03d68d1c-162c-8b6e-70f9-647b0ea97adb\"> </a><a name=\"hc03d68d1c-162c-8b6e-70f9-647b0ea97adb\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource SubstanceDefinition &quot;03d68d1c-162c-8b6e-70f9-647b0ea97adb&quot; </p></div><p><b>manufacturer</b>: See on this page: Organization/062bf235-44e2-55c4-9213-bbe5e12d5620</p><h3>Names</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Name</b></td></tr><tr><td style=\"display: none\">*</td><td>Stelbatolol</td></tr></table></div>"
      ] ; #
      fhir:manufacturer ( [
    fhir:reference [ fhir:v "Organization/062bf235-44e2-55c4-9213-bbe5e12d5620" ] # Organization\/substance-manufacturer
      ] ) ; #
      fhir:name ( [
    fhir:name [ fhir:v "Stelbatolol" ]
      ] ) . #

    <urn:uuid:062bf235-44e2-55c4-9213-bbe5e12d5620> a fhir:Organization ;
      fhir:id [ fhir:v "062bf235-44e2-55c4-9213-bbe5e12d5620"] ; # substance-manufacturer
      fhir:text [
    fhir:status [ fhir:v "generated" ] ;
    fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Organization_062bf235-44e2-55c4-9213-bbe5e12d5620\"> </a><p><b>Generated Narrative: Organization</b><a name=\"062bf235-44e2-55c4-9213-bbe5e12d5620\"> </a><a name=\"hc062bf235-44e2-55c4-9213-bbe5e12d5620\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Organization &quot;062bf235-44e2-55c4-9213-bbe5e12d5620&quot; </p></div><p><b>identifier</b>: <code>urn:oid:2.16.840.1.113883.4.82</code>/3003040516</p><p><b>active</b>: true</p><p><b>type</b>: Drug Substance Manufacture <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-organization-type.html\">Pharmaceutical Organization Type Codes</a>#drug-substance-manufacture)</span></p><p><b>name</b>: AAA Molybdenum Products, Inc.</p><h3>Contacts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Address</b></td></tr><tr><td style=\"display: none\">*</td><td>7233 W 116th Pl Ste C Broomfield Colorado 80020 USA </td></tr></table></div>"
      ] ; #
      fhir:identifier ( [
    fhir:system [ fhir:v "urn:oid:2.16.840.1.113883.4.82"^^xsd:anyURI ] ; #  FDA establishment identifier
    fhir:value [ fhir:v "3003040516" ]
      ] ) ; #
      fhir:active [ fhir:v "true"^^xsd:boolean] ; #
      fhir:type ( [
        ( fhir:coding [
    fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/pharmaceutical-organization-type"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "drug-substance-manufacture" ] ;
    fhir:display [ fhir:v "Drug Substance Manufacture" ]     ] )
      ] ) ; #
      fhir:name [ fhir:v "AAA Molybdenum Products, Inc."] ; #
      fhir:contact ( [
    fhir:address [
          ( fhir:line [ fhir:v "7233 W 116th Pl" ] [ fhir:v "Ste C" ] ) ;
    fhir:city [ fhir:v "Broomfield" ] ;
    fhir:state [ fhir:v "Colorado" ] ;
    fhir:postalCode [ fhir:v "80020" ] ;
    fhir:country [ fhir:v "USA" ]     ]
      ] ) . #