Pharmaceutical Quality (Industry)
1.0.0 - STU1

Pharmaceutical Quality (Industry), published by HL7 International / Biomedical Research and Regulation. This guide is not an authorized publication; it is the continuous build for version 1.0.0 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/uv-dx-pq/ and changes regularly. See the Directory of published versions

## : Example: Bundle - Process Validation, biologic product - JSON Representation

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    {
      "resourceType" : "Bundle",
      "id" : "bundle-product-process-validation-pq-ex3-prod-bio",
      "meta" : //  Product Process Validation - Biologic
      {
        "profile" : [
          🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Bundle-product-process-validation-pq"
        ]
      },
      "type" : "collection",
      "entry" : [
        {
          "fullUrl" : "urn:uuid:2038e4c7-22b8-4c56-2d28-6c077648763f",
          "resource" : {
            "resourceType" : "PlanDefinition",
            "id" : "plandefinition-drug-pq-ex1-validation-protocol",
            "text" : // id value="validationProtocol"/
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"PlanDefinition_plandefinition-drug-pq-ex1-validation-protocol\"> </a><p><b>Generated Narrative: PlanDefinition</b><a name=\"plandefinition-drug-pq-ex1-validation-protocol\"> </a><a name=\"hcplandefinition-drug-pq-ex1-validation-protocol\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource PlanDefinition &quot;plandefinition-drug-pq-ex1-validation-protocol&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/PlanDefinition/2038e4c7-22b8-4c56-2d28-6c077648763f</code></p><p><b>title</b>: DP PROCESS VALIDATION</p><p><b>type</b>: Workflow Definition <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.0.0/CodeSystem-plan-definition-type.html\">PlanDefinitionType</a>#workflow-definition; <a href=\"CodeSystem-pharmaceutical-plan-type.html\">Pharmaceutical Plan Type Codes</a>#process-validation &quot;Process Validation&quot;)</span></p><p><b>status</b>: active</p><p><b>subject</b>: See on this page: MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5</p><p><b>description</b>: Pre-defined validation acceptance criteria were established based on manufacturing development data derived from process characterization studies...</p><blockquote><p><b>action</b></p><p><b>title</b>: Formulation Buffer Preparation Process Parameter Step</p><p><b>code</b>: Formulation Buffer Preparation Process Parameter Step <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-manufacturing-step.html\">Manufacturing Step Codes</a>#FormulationBufferPreparationProcessParameterStep)</span></p><blockquote><p><b>action</b></p><p><b>title</b>: Formulation Buffer Preparation Process Parameter Step</p><p><b>code</b>: FormulationBufferPreparationProcessParameterStep <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote></blockquote></blockquote><blockquote><p><b>action</b></p><p><b>title</b>: Formulation Buffer Preparation Performance Indicator Results</p><p><b>code</b>: Formulation Buffer Preparation Performance Indicator Results <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-manufacturing-step.html\">Manufacturing Step Codes</a>#FormulationBufferPreparationPerformanceIndicatorStep)</span></p><blockquote><p><b>action</b></p><p><b>title</b>: ???</p><p><b>code</b>: ??? <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote></blockquote></blockquote><blockquote><p><b>action</b></p><p><b>title</b>: Thawing and Formulation Process Parameter Results</p><p><b>code</b>: Thawing and Formulation Process Parameter Resultss <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-manufacturing-step.html\">Manufacturing Step Codes</a>#ThawingandFormulationProcessParameterResultsStep)</span></p><blockquote><p><b>action</b></p><p><b>title</b>: ???</p><p><b>code</b>: ??? <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote></blockquote></blockquote><blockquote><p><b>action</b></p><p><b>title</b>: Thawing and Formulation Performance Indicator Results</p><p><b>code</b>: Thawing and Formulation Performance Indicator Results <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-manufacturing-step.html\">Manufacturing Step Codes</a>#ThawingandFormulationPerformanceIndicatorResultsStep)</span></p><blockquote><p><b>action</b></p><p><b>title</b>: ???</p><p><b>code</b>: ??? <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote></blockquote></blockquote><blockquote><p><b>action</b></p><p><b>title</b>: Bioburden Reduction Filtration Process Parameter Results</p><p><b>code</b>: Bioburden Reduction Filtration Process Parameter Results <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-manufacturing-step.html\">Manufacturing Step Codes</a>#BioburdenReductionFiltrationProcessParameterResultsStep)</span></p><h3>Actions</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Definition[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Test <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/74515b3c-5134-448a-9c19-949ce1958434\">http://example-server.com/fhir/ObservationDefinition/74515b3c-5134-448a-9c19-949ce1958434</a></td></tr></table></blockquote><blockquote><p><b>action</b></p><p><b>title</b>: Bioburden Reduction Filtration Performance Indicator Results</p><p><b>code</b>: Bioburden Reduction Filtration Performance Indicator Results <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-manufacturing-step.html\">Manufacturing Step Codes</a>#BioburdenReductionFiltrationPerformanceIndicatorResultsStep)</span></p><h3>Actions</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Definition[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Test <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9c19-939ce1958434\">http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9c19-939ce1958434</a></td></tr><tr><td style=\"display: none\">*</td><td>Test <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/75515b3c-5134-448a-9c19-949ce1958434\">http://example-server.com/fhir/ObservationDefinition/75515b3c-5134-448a-9c19-949ce1958434</a></td></tr></table></blockquote><blockquote><p><b>action</b></p><p><b>title</b>: Media Challenge Hold Times</p><p><b>code</b>: Media Challenge Hold Times <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-manufacturing-step.html\">Manufacturing Step Codes</a>#MediaChallengeHoldTimesStep)</span></p><h3>Actions</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Definition[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Test <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/75515c3c-5134-448a-9c19-949ce1958434\">http://example-server.com/fhir/ObservationDefinition/75515c3c-5134-448a-9c19-949ce1958434</a></td></tr></table></blockquote><blockquote><p><b>action</b></p><p><b>title</b>: Media Challenge Results</p><p><b>code</b>: Media Challenge Results <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-manufacturing-step.html\">Manufacturing Step Codes</a>#MediaChallengeResultsStep)</span></p><h3>Actions</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Definition[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Test <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9c19-939ce1958524\">http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9c19-939ce1958524</a></td></tr><tr><td style=\"display: none\">*</td><td>Test <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9d19-939ce1958524\">http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9d19-939ce1958524</a></td></tr></table></blockquote><blockquote><p><b>action</b></p><p><b>title</b>: Filtered Formulated Drug Product Performance Indicator Results</p><p><b>code</b>: Filtered Formulated Drug Product Performance Indicator Results <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-manufacturing-step.html\">Manufacturing Step Codes</a>#FilteredFormulatedDrugProductPerformanceIndicatorResultsStep)</span></p><h3>Actions</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Definition[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Test <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/64525a3d-5034-448a-9c19-938ce1958424\">http://example-server.com/fhir/ObservationDefinition/64525a3d-5034-448a-9c19-938ce1958424</a></td></tr><tr><td style=\"display: none\">*</td><td>Test <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/64525a4d-5034-448a-9c19-938ce1958424\">http://example-server.com/fhir/ObservationDefinition/64525a4d-5034-448a-9c19-938ce1958424</a></td></tr><tr><td style=\"display: none\">*</td><td>Test <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/64525a33-5034-448a-9c19-938ce1958424\">http://example-server.com/fhir/ObservationDefinition/64525a33-5034-448a-9c19-938ce1958424</a></td></tr></table></blockquote><blockquote><p><b>action</b></p><p><b>title</b>: Fill Weight Summary</p><p><b>code</b>: Fill Weight Summary <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-manufacturing-step.html\">Manufacturing Step Codes</a>#FillWeightSummaryStep)</span></p><h3>Actions</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Definition[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Test <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9c19-939ce2958524\">http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9c19-939ce2958524</a></td></tr></table></blockquote><blockquote><p><b>action</b></p><p><b>title</b>: Filling Homogeneity Quality Attributes</p><p><b>code</b>: Filling Homogeneity Quality Attributes <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-manufacturing-step.html\">Manufacturing Step Codes</a>#FillingHomogeneityQualityAttributesStep)</span></p><h3>Actions</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Definition[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Conclusion <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/22525a3c-5035-448a-9c19-938ce1958424\">http://example-server.com/fhir/ObservationDefinition/22525a3c-5035-448a-9c19-938ce1958424</a></td></tr></table></blockquote><blockquote><p><b>action</b></p><p><b>title</b>: Filling Results Summary</p><p><b>code</b>: Filling Results Summary <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-manufacturing-step.html\">Manufacturing Step Codes</a>#FillingResultsSummaryStep)</span></p><h3>Actions</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Definition[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Test <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/74515b3c-5134-448a-9c19-939ce1958524\">http://example-server.com/fhir/ObservationDefinition/74515b3c-5134-448a-9c19-939ce1958524</a></td></tr><tr><td style=\"display: none\">*</td><td>Test <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/74515b3c-5234-448a-9c19-939ce1958524\">http://example-server.com/fhir/ObservationDefinition/74515b3c-5234-448a-9c19-939ce1958524</a></td></tr></table></blockquote><blockquote><p><b>action</b></p><p><b>title</b>: Statistical Evaluation of Homogeneity Data</p><p><b>code</b>: Statistical Evaluation of Homogeneity Data <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-manufacturing-step.html\">Manufacturing Step Codes</a>#StatisticalEvaluationOfHomogeneityDataStep)</span></p><h3>Actions</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Definition[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Test <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/74515b3c-5134-448a-9c19-939ce1958534\">http://example-server.com/fhir/ObservationDefinition/74515b3c-5134-448a-9c19-939ce1958534</a></td></tr><tr><td style=\"display: none\">*</td><td>Test <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/74515b3c-5234-448a-9c19-939ce1958524\">http://example-server.com/fhir/ObservationDefinition/74515b3c-5234-448a-9c19-939ce1958524</a></td></tr></table></blockquote><blockquote><p><b>action</b></p><p><b>title</b>: Consistency of the Lyophilization Process</p><p><b>code</b>: Consistency of the Lyophilization Process <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-manufacturing-step.html\">Manufacturing Step Codes</a>#ConsistencyoftheLyophilizationProcessStep)</span></p><h3>Actions</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Definition[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Test <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/fc27b6d6-9fe2-91c2-2d16-47cb5b295e72\">http://example-server.com/fhir/ObservationDefinition/fc27b6d6-9fe2-91c2-2d16-47cb5b295e72</a></td></tr><tr><td style=\"display: none\">*</td><td>Definition <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"Bundle-bundle-product-process-validation-pq-ex3-prod-bio.html\">Lyophilization</a></td></tr></table></blockquote><blockquote><p><b>action</b></p><p><b>title</b>: Lyophilization Homogeneity</p><p><b>code</b>: Lyophilization Homogeneity Results <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-manufacturing-step.html\">Manufacturing Step Codes</a>#LyophilizationHomogeneityStep)</span></p><h3>Actions</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Definition[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Test <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/64525a3d-5134-448a-9c19-938ce1958424\">http://example-server.com/fhir/ObservationDefinition/64525a3d-5134-448a-9c19-938ce1958424</a></td></tr><tr><td style=\"display: none\">*</td><td>Test <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td><a href=\"http://example-server.com/fhir/ObservationDefinition/64525a3d-5144-448a-9c19-938ce1958424\">http://example-server.com/fhir/ObservationDefinition/64525a3d-5144-448a-9c19-938ce1958424</a></td></tr></table></blockquote></div>"
            },
            "url" : "http://example-server.com/fhir/PlanDefinition/2038e4c7-22b8-4c56-2d28-6c077648763f",
            "title" : "DP PROCESS VALIDATION",
            "type" : // <meta>
                        <profile value="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/PlanDefinition-drug-pq"/>
                    </meta>
            // http://example-server.com/fhir/PlanDefinition/2038e4c7-22b8-4c56-2d28-6c077648763f
            {
              "coding" : [
                {
                  "system" : "http://terminology.hl7.org/CodeSystem/plan-definition-type",
                  "code" : "workflow-definition",
                  "display" : "Workflow Definition"
                },
                {
                  "system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-plan-type",
                  "code" : "process-validation",
                  "display" : "Process Validation"
                }
              ]
            },
            "status" : "active",
            "subjectReference" : {
              "reference" : "MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"
            },
            "description" : "Pre-defined validation acceptance criteria were established based on manufacturing development data derived from process characterization studies...",
            "action" : [
              // MedicinalProductDefinition/medicinalproductdefinition-drug-product-pq-ex1
              {
                "title" : "Formulation Buffer Preparation Process Parameter Step",
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://terminology.hl7.org/CodeSystem/manufacturing-step",
                      "code" : "FormulationBufferPreparationProcessParameterStep",
                      "display" : "Formulation Buffer Preparation Process Parameter Step"
                    }
                  ],
                  "text" : "Formulation Buffer Preparation Process Parameter Step"
                },
                "action" : [
                  {
                    "title" : "Formulation Buffer Preparation Process Parameter Step",
                    "code" : //  this level is not really needed here, could remove. But in the case where there are different timings, it is needed, so it is here for consistency
                    {
                      "text" : "FormulationBufferPreparationProcessParameterStep"
                    },
                    "action" : [
                      {
                        "code" : {
                          "text" : "Conclusion"
                        },
                        "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/22515a3c-5034-448a-9c19-938ce1958424"
                      },
                      // ObservationDefinition/conclusion
                      {
                        "code" : {
                          "text" : "Test"
                        },
                        "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/fd17b5d6-9fe1-91c2-2d06-47cb5b295e72"
                      },
                      // ObservationDefinition/bufferVesselMixingSpeed
                      {
                        "code" : {
                          "text" : "Test"
                        },
                        "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e73"
                      }
                    ]
                  }
                ]
              },
              // ObservationDefinition/bufferVesselMixingTime
              {
                "title" : "Formulation Buffer Preparation Performance Indicator Results",
                "code" : // text value="Overall set of actions"/
                {
                  "coding" : [
                    {
                      "system" : "http://terminology.hl7.org/CodeSystem/manufacturing-step",
                      "code" : "FormulationBufferPreparationPerformanceIndicatorStep",
                      "display" : "Formulation Buffer Preparation Performance Indicator Results"
                    }
                  ]
                },
                "action" : [
                  {
                    "title" : "???",
                    "code" : {
                      "text" : "???"
                    },
                    "action" : [
                      {
                        "code" : {
                          "text" : "Test"
                        },
                        "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/fc17b5d6-9fe1-91c2-2d16-47cb5b295e72"
                      },
                      // ObservationDefinition/FBPPIpH
                      {
                        "code" : {
                          "text" : "Test"
                        },
                        "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/64525a3c-5034-448a-9c19-938ce1958424"
                      },
                      // ObservationDefinition/Osmolality
                      {
                        "code" : {
                          "text" : "Test"
                        },
                        "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/64515a3c-5134-448a-9c19-939ce1958424"
                      },
                      // ObservationDefinition/Conductivity
                      {
                        "code" : {
                          "text" : "Test"
                        },
                        "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9c19-939ce1958424"
                      },
                      // ObservationDefinition/Bioburden
                      {
                        "code" : {
                          "text" : "Test"
                        },
                        "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9c19-949ce1958424"
                      }
                    ]
                  }
                ]
              },
              // ObservationDefinition/BacterialEndotoxins
              {
                "title" : "Thawing and Formulation Process Parameter Results",
                "code" : // text value="Overall set of actions"/
                {
                  "coding" : [
                    {
                      "system" : "http://terminology.hl7.org/CodeSystem/manufacturing-step",
                      "code" : "ThawingandFormulationProcessParameterResultsStep",
                      "display" : "Thawing and Formulation Process Parameter Resultss"
                    }
                  ]
                },
                "action" : [
                  {
                    "title" : "???",
                    "code" : {
                      "text" : "???"
                    },
                    "action" : [
                      {
                        "code" : {
                          "text" : "Test"
                        },
                        "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/74515a3c-5034-448a-9c19-938ce1958424"
                      },
                      // ObservationDefinition/ThawingTemp
                      {
                        "code" : {
                          "text" : "Test"
                        },
                        "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/fc27b5d6-9fe2-91c2-2d16-47cb5b295e72"
                      },
                      // ObservationDefinition/ThawingTime
                      {
                        "code" : {
                          "text" : "Test"
                        },
                        "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e72"
                      },
                      // ObservationDefinition/formulationVesselMixingSpeed
                      {
                        "code" : {
                          "text" : "Test"
                        },
                        "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/fc27b5d5-9fe1-92c2-2d06-47cb5b295e73"
                      }
                    ]
                  }
                ]
              },
              // ObservationDefinition/formulationVesselMixingTime
              {
                "title" : "Thawing and Formulation Performance Indicator Results",
                "code" : // text value="Overall set of actions"/
                {
                  "coding" : [
                    {
                      "system" : "http://terminology.hl7.org/CodeSystem/manufacturing-step",
                      "code" : "ThawingandFormulationPerformanceIndicatorResultsStep",
                      "display" : "Thawing and Formulation Performance Indicator Results"
                    }
                  ]
                },
                "action" : [
                  {
                    "title" : "???",
                    "code" : {
                      "text" : "???"
                    },
                    "action" : [
                      {
                        "code" : {
                          "text" : "Test"
                        },
                        "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/fc27b5d6-9fe1-91c2-2d16-47cb5b295e72"
                      },
                      // ObservationDefinition/ThawingFBPPIpH
                      {
                        "code" : {
                          "text" : "Test"
                        },
                        "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/64515a3c-5034-448a-9c19-938ce1958424"
                      },
                      // ObservationDefinition/ThawingOsmolality
                      {
                        "code" : {
                          "text" : "Test"
                        },
                        "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/74515a3c-5134-448a-9c19-939ce1958424"
                      },
                      // ObservationDefinition/ThawingConductivity
                      {
                        "code" : {
                          "text" : "Test"
                        },
                        "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/64515b4c-5134-448a-9c19-949ce1958424"
                      },
                      // ObservationDefinition/ThawingBacterialEndotoxins
                      {
                        "code" : {
                          "text" : "Test"
                        },
                        "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9c19-949ce1958434"
                      }
                    ]
                  }
                ]
              },
              // ObservationDefinition/Polysorbate
              {
                "title" : "Bioburden Reduction Filtration Process Parameter Results",
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://terminology.hl7.org/CodeSystem/manufacturing-step",
                      "code" : "BioburdenReductionFiltrationProcessParameterResultsStep",
                      "display" : "Bioburden Reduction Filtration Process Parameter Results"
                    }
                  ]
                },
                "action" : [
                  {
                    "code" : {
                      "text" : "Test"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/74515b3c-5134-448a-9c19-949ce1958434"
                  }
                ]
              },
              // ObservationDefinition/FiltrationPressure
              {
                "title" : "Bioburden Reduction Filtration Performance Indicator Results",
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://terminology.hl7.org/CodeSystem/manufacturing-step",
                      "code" : "BioburdenReductionFiltrationPerformanceIndicatorResultsStep",
                      "display" : "Bioburden Reduction Filtration Performance Indicator Results"
                    }
                  ]
                },
                "action" : [
                  {
                    "code" : {
                      "text" : "Test"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9c19-939ce1958434"
                  },
                  // ObservationDefinition/PreFiltrationBioburden
                  {
                    "code" : {
                      "text" : "Test"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/75515b3c-5134-448a-9c19-949ce1958434"
                  }
                ]
              },
              // ObservationDefinition/PostFiltrationFilterIntegrity
              {
                "title" : "Media Challenge Hold Times",
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://terminology.hl7.org/CodeSystem/manufacturing-step",
                      "code" : "MediaChallengeHoldTimesStep",
                      "display" : "Media Challenge Hold Times"
                    }
                  ]
                },
                "action" : [
                  {
                    "code" : {
                      "text" : "Test"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/75515c3c-5134-448a-9c19-949ce1958434"
                  }
                ]
              },
              // ObservationDefinition/MediaHoldTime
              {
                "title" : "Media Challenge Results",
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://terminology.hl7.org/CodeSystem/manufacturing-step",
                      "code" : "MediaChallengeResultsStep",
                      "display" : "Media Challenge Results"
                    }
                  ]
                },
                "action" : [
                  {
                    "code" : {
                      "text" : "Test"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9c19-939ce1958524"
                  },
                  // ObservationDefinition/MediaBioburden
                  {
                    "code" : {
                      "text" : "Test"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9d19-939ce1958524"
                  }
                ]
              },
              // ObservationDefinition/GrowthPromotion
              {
                "title" : "Filtered Formulated Drug Product Performance Indicator Results",
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://terminology.hl7.org/CodeSystem/manufacturing-step",
                      "code" : "FilteredFormulatedDrugProductPerformanceIndicatorResultsStep",
                      "display" : "Filtered Formulated Drug Product Performance Indicator Results"
                    }
                  ]
                },
                "action" : [
                  {
                    "code" : {
                      "text" : "Test"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/64525a3d-5034-448a-9c19-938ce1958424"
                  },
                  // ObservationDefinition/SE-UHPLCMainPeak
                  {
                    "code" : {
                      "text" : "Test"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/64525a4d-5034-448a-9c19-938ce1958424"
                  },
                  // ObservationDefinition/SE-UHPLCMainPeakGraph
                  {
                    "code" : {
                      "text" : "Test"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/64525a33-5034-448a-9c19-938ce1958424"
                  }
                ]
              },
              // ObservationDefinition/SE-UHPLCHMW
              {
                "title" : "Fill Weight Summary",
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://terminology.hl7.org/CodeSystem/manufacturing-step",
                      "code" : "FillWeightSummaryStep",
                      "display" : "Fill Weight Summary"
                    }
                  ]
                },
                "action" : [
                  {
                    "code" : {
                      "text" : "Test"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9c19-939ce2958524"
                  }
                ]
              },
              // ObservationDefinition/FillWeight
              {
                "title" : "Filling Homogeneity Quality Attributes",
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://terminology.hl7.org/CodeSystem/manufacturing-step",
                      "code" : "FillingHomogeneityQualityAttributesStep",
                      "display" : "Filling Homogeneity Quality Attributes"
                    }
                  ],
                  "text" : "Filling Homogeneity Quality Attributes"
                },
                "action" : [
                  {
                    "code" : {
                      "text" : "Conclusion"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/22525a3c-5035-448a-9c19-938ce1958424"
                  }
                ]
              },
              // ObservationDefinition/conclusionHomogeneity
              {
                "title" : "Filling Results Summary",
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://terminology.hl7.org/CodeSystem/manufacturing-step",
                      "code" : "FillingResultsSummaryStep",
                      "display" : "Filling Results Summary"
                    }
                  ]
                },
                "action" : [
                  {
                    "code" : {
                      "text" : "Test"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/74515b3c-5134-448a-9c19-939ce1958524"
                  },
                  // ObservationDefinition/ProteinConcentration
                  {
                    "code" : {
                      "text" : "Test"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/74515b3c-5234-448a-9c19-939ce1958524"
                  }
                ]
              },
              // ObservationDefinition/Polysorbate80Concentration
              {
                "title" : "Statistical Evaluation of Homogeneity Data",
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://terminology.hl7.org/CodeSystem/manufacturing-step",
                      "code" : "StatisticalEvaluationOfHomogeneityDataStep",
                      "display" : "Statistical Evaluation of Homogeneity Data"
                    }
                  ]
                },
                "action" : [
                  {
                    "code" : {
                      "text" : "Test"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/74515b3c-5134-448a-9c19-939ce1958534"
                  },
                  // ObservationDefinition/ProteinConcentrationStats
                  {
                    "code" : {
                      "text" : "Test"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/74515b3c-5234-448a-9c19-939ce1958524"
                  }
                ]
              },
              // ObservationDefinition/Polysorbate80Concentration
              {
                "title" : "Consistency of the Lyophilization Process",
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://terminology.hl7.org/CodeSystem/manufacturing-step",
                      "code" : "ConsistencyoftheLyophilizationProcessStep",
                      "display" : "Consistency of the Lyophilization Process"
                    }
                  ]
                },
                "action" : [
                  {
                    "code" : {
                      "text" : "Test"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/fc27b6d6-9fe2-91c2-2d16-47cb5b295e72"
                  },
                  // ObservationDefinition/ResidualMoisture
                  {
                    "code" : {
                      "text" : "Definition"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ActivityDefinition/b664977d-799d-a1ce-928a-6def2a9955bd"
                  }
                ]
              },
              // ActivityDefinition/LyophilizationAct
              {
                "title" : "Lyophilization Homogeneity",
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://terminology.hl7.org/CodeSystem/manufacturing-step",
                      "code" : "LyophilizationHomogeneityStep",
                      "display" : "Lyophilization Homogeneity Results"
                    }
                  ]
                },
                "action" : [
                  //  there are 2 types of obs that correspond to this. Ones per batch, with a %, and ones that are not per batch and have a conclusion (and a number of samples)
                  {
                    "code" : {
                      "text" : "Test"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/64525a3d-5134-448a-9c19-938ce1958424"
                  },
                  // ObservationDefinition/SE-UHPLCMainPeakLyoph
                  {
                    "code" : {
                      "text" : "Test"
                    },
                    "definitionCanonical" : "http://example-server.com/fhir/ObservationDefinition/64525a3d-5144-448a-9c19-938ce1958424"
                  }
                ]
              }
            ]
          }
        },
        // ObservationDefinition/SE-UHPLCHMWLyoph
        //  there are 2 types of obs that correspond to this. Ones per batch, with a %, and ones that are not per batch and have a conclusion (and a number of samples)
        //  no tests just a conclusion
        {
          "fullUrl" : "urn:uuid:b664977d-799d-a1ce-928a-6def2a9955bd",
          "resource" : {
            "resourceType" : "ActivityDefinition",
            "id" : "b664977d-799d-a1ce-928a-6def2a9955bd",
            "text" : // LyophilizationAct
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ActivityDefinition_b664977d-799d-a1ce-928a-6def2a9955bd\"> </a><p><b>Generated Narrative: ActivityDefinition</b><a name=\"b664977d-799d-a1ce-928a-6def2a9955bd\"> </a><a name=\"hcb664977d-799d-a1ce-928a-6def2a9955bd\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ActivityDefinition &quot;b664977d-799d-a1ce-928a-6def2a9955bd&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ActivityDefinition/b664977d-799d-a1ce-928a-6def2a9955bd</code></p><p><b>title</b>: Lyophilization</p><p><b>status</b>: active</p></div>"
            },
            "url" : "http://example-server.com/fhir/ActivityDefinition/b664977d-799d-a1ce-928a-6def2a9955bd",
            "title" : "Lyophilization",
            "status" : "active"
          }
        },
        // <meta>
    			        <profile value="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/ActivityDefinition-test-drug-pq"/>
    			    </meta>
        // http://example-server.com/fhir/ActivityDefinition/b664977d-799d-a1ce-928a-6def2a9955bd
        {
          "fullUrl" : "urn:uuid:378fbe5f-5926-3a5c-4c64-5428df877b08",
          "resource" : {
            "resourceType" : "Organization",
            "id" : "378fbe5f-5926-3a5c-4c64-5428df877b08",
            "text" : // 378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Organization_378fbe5f-5926-3a5c-4c64-5428df877b08\"> </a><p><b>Generated Narrative: Organization</b><a name=\"378fbe5f-5926-3a5c-4c64-5428df877b08\"> </a><a name=\"hc378fbe5f-5926-3a5c-4c64-5428df877b08\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Organization &quot;378fbe5f-5926-3a5c-4c64-5428df877b08&quot; </p></div><p><b>identifier</b>: <code>urn:oid:2.16.840.1.113883.4.82</code>/3007270600</p><p><b>active</b>: true</p><p><b>type</b>: Analytical Testing - Release <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-organization-type.html\">Pharmaceutical Organization Type Codes</a>#analytical-testing-release)</span></p><p><b>name</b>: Testing Lab</p></div>"
            },
            "identifier" : [
              {
                "system" : "urn:oid:2.16.840.1.113883.4.82",
                "value" : "3007270600"
              }
            ],
            "active" : true,
            "type" : [
              {
                "coding" : [
                  {
                    "system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-organization-type",
                    "code" : "analytical-testing-release",
                    "display" : "Analytical Testing - Release"
                  }
                ]
              }
            ],
            "name" : "Testing Lab"
          }
        },
        {
          "fullUrl" : "urn:uuid:b664977d-799d-a1ce-928a-5def2a9955bd",
          "resource" : {
            "resourceType" : "DiagnosticReport",
            "id" : "processValidationReport",
            "text" : //  ideally this wants a subject, but it can only be a Medication (batch) and we have multiple.
                         however the observations themselves do have subjects
            {
              "status" : "extensions",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"DiagnosticReport_processValidationReport\"> </a><p><b>Generated Narrative: DiagnosticReport</b><a name=\"processValidationReport\"> </a><a name=\"hcprocessValidationReport\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource DiagnosticReport &quot;processValidationReport&quot; </p></div><p><b>Triggered by</b>: <a href=\"Bundle-bundle-batch-analysis-pq-ex1-prod.html#PlanDefinition_2038e4c7-22b8-4c56-2d28-6c077648763f\">PlanDefinition/2038e4c7-22b8-4c56-2d28-6c077648763f</a></p><p><b>status</b>: final</p><p><b>code</b>: Process Validation Report <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-report-type.html\">Pharmaceutical Report Type Codes</a>#Process Validation Report)</span></p><p><b>effective</b>: 2020-12</p><p><b>result</b>: </p><ul><li>See on this page: Observation/9c56948a-2a39-6609-1c01-4d197ea57a33</li><li>See on this page: Observation/9c56948a-3a39-6609-1c01-4d197ea57a33</li><li>See on this page: Observation/9c56948a-4a39-6609-1c01-4d197ea57a33</li><li>See on this page: Observation/9c56948a-2a39-6609-2c01-4d197ea57a33</li><li>See on this page: Observation/9c56948a-3a39-6609-2c01-4d197ea57a33</li><li>See on this page: Observation/9c56948a-4a39-6609-3c01-4d197ea57a33</li><li>See on this page: Observation/44aa47fd-8964-4f96-6495-b2bec7f160e7</li><li>See on this page: Observation/54aa47fd-8964-4f96-6495-b2bec7f160e7</li><li>See on this page: Observation/54aa48fd-8964-4f96-6495-b2bec7f160e7</li><li>See on this page: Observation/44aa47fd-8964-4f96-6495-b2bec7f161e7</li><li>See on this page: Observation/54aa47fd-8964-4f96-6495-b2bec7f162e7</li><li>See on this page: Observation/54aa48fd-8964-4f96-6495-b2bec7f163e7</li><li>See on this page: Observation/44aa47fd-8964-5f96-6495-b2bec7f161e7</li><li>See on this page: Observation/44aa47fd-9964-5f96-6495-b2bec7f161e8</li><li>See on this page: Observation/44aa47fd-8964-5f96-6495-b2bec7f161e8</li><li>See on this page: Observation/44aa47fd-8964-5f96-7495-b2bec7f161e8</li><li>See on this page: Observation/44aa47fd-9964-5f97-6495-b2bec7f161e8</li><li>See on this page: Observation/44aa47fd-8964-5f98-6495-b2bec7f161e8</li><li>See on this page: Observation/44aa47fd-8964-5f99-7495-b2bec7f161e8</li><li>See on this page: Observation/54aa47fd-9964-5f97-6495-b2bec7f161e8</li><li>See on this page: Observation/64aa47fd-8964-5f98-6495-b2bec7f161e8</li><li>See on this page: Observation/74aa47fd-8964-5f99-7495-b2bec7f161e8</li><li>See on this page: Observation/44ba47fd-8964-4f96-6495-b2bec7f161e7</li><li>See on this page: Observation/54ca47fd-8964-4f96-6495-b2bec7f162e7</li><li>See on this page: Observation/54da48fd-8964-4f96-6495-b2bec7f163e7</li><li>See on this page: Observation/44ba47fd-8964-5f96-6495-b2bec7f161e7</li><li>See on this page: Observation/44ba47fd-8964-4f97-6495-b2bec7f161e7</li><li>See on this page: Observation/54ca47fd-8964-4f98-6495-b2bec7f162e7</li><li>See on this page: Observation/54da48fd-8964-4f99-6495-b2bec7f163e7</li><li>See on this page: Observation/55aa47fd-9964-5f97-6495-b2bec7f161e8</li><li>See on this page: Observation/45aa47fd-8964-4f96-6495-b2bec7f160f7</li><li>See on this page: Observation/54aa47fd-9964-5f97-6495-b2bec8f161e8</li><li>See on this page: Observation/54aa47fd-9964-5f97-6495-b2bec8f162e8</li><li>See on this page: Observation/54aa47fd-9965-5f97-6495-b2bec8f161e8</li><li>See on this page: Observation/44ba47fd-8964-4f96-6495-b2bec7f161e8</li><li>See on this page: Observation/44ba47fd-9964-4f96-6495-b2bec7f161e8</li><li>See on this page: Observation/44ba47fd-9964-4f96-6496-b2bec7f161e8</li><li>See on this page: Observation/54ba47fd-8964-4f96-6495-b2bec7f161e7</li><li>See on this page: Observation/54ba47fd-8964-4f96-6495-b2bec7f161e8</li><li>See on this page: Observation/54ba47fd-8964-4f96-6495-b2bec7f161e9</li><li>See on this page: Observation/54ba48fd-8964-4f96-6495-b2bec7f161e7</li><li>See on this page: Observation/54bb47fd-8964-4f96-6495-b2bec7f161e7</li><li>See on this page: Observation/54ba47fd-9964-4f96-6495-b2bec7f161e8</li><li>See on this page: Observation/54ba47fe-8964-4f96-6495-b2bec7f161e9</li><li>See on this page: Observation/64ba48fd-8964-4f96-6495-b2bec7f161e7</li></ul><p><b>conclusion</b>: The samples have been assessed and the conclusion is...</p></div>"
            },
            "extension" : [
              {
                "url" : "http://hl7.org/fhir/StructureDefinition/workflow-triggeredBy",
                "valueReference" : {
                  "reference" : "PlanDefinition/2038e4c7-22b8-4c56-2d28-6c077648763f"
                }
              }
            ],
            "status" : "final",
            "code" : // PlanDefinition/plandefinition-drug-pq-ex1-validation-protocol
            {
              "coding" : [
                {
                  "system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-report-type",
                  "code" : "Process Validation Report",
                  "display" : "Process Validation Report"
                }
              ]
            },
            "effectiveDateTime" : "2020-12",
            "result" : [
              {
                "reference" : "Observation/9c56948a-2a39-6609-1c01-4d197ea57a33"
              },
              // Observation/bufferVesselMixingSpeed1
              {
                "reference" : "Observation/9c56948a-3a39-6609-1c01-4d197ea57a33"
              },
              // Observation/bufferVesselMixingSpeed2
              {
                "reference" : "Observation/9c56948a-4a39-6609-1c01-4d197ea57a33"
              },
              // Observation/bufferVesselMixingSpeed3
              {
                "reference" : "Observation/9c56948a-2a39-6609-2c01-4d197ea57a33"
              },
              // Observation/bufferVesselMixingTime1
              {
                "reference" : "Observation/9c56948a-3a39-6609-2c01-4d197ea57a33"
              },
              // Observation/bufferVesselMixingTime2
              {
                "reference" : "Observation/9c56948a-4a39-6609-3c01-4d197ea57a33"
              },
              // Observation/bufferVesselMixingTime3
              {
                "reference" : "Observation/44aa47fd-8964-4f96-6495-b2bec7f160e7"
              },
              // Observation/ph1
              {
                "reference" : "Observation/54aa47fd-8964-4f96-6495-b2bec7f160e7"
              },
              // Observation/ph2
              {
                "reference" : "Observation/54aa48fd-8964-4f96-6495-b2bec7f160e7"
              },
              // Observation/ph3
              {
                "reference" : "Observation/44aa47fd-8964-4f96-6495-b2bec7f161e7"
              },
              // Observation/osmolality1
              {
                "reference" : "Observation/54aa47fd-8964-4f96-6495-b2bec7f162e7"
              },
              // Observation/osmolality2
              {
                "reference" : "Observation/54aa48fd-8964-4f96-6495-b2bec7f163e7"
              },
              // Observation/osmolality3
              {
                "reference" : "Observation/44aa47fd-8964-5f96-6495-b2bec7f161e7"
              },
              // Observation/postFiltrationFilterIntegrity1
              {
                "reference" : "Observation/44aa47fd-9964-5f96-6495-b2bec7f161e8"
              },
              // Observation/mediaChallengeHoldTimesStep1
              {
                "reference" : "Observation/44aa47fd-8964-5f96-6495-b2bec7f161e8"
              },
              // Observation/mediaChallengeHoldTimesStep2
              {
                "reference" : "Observation/44aa47fd-8964-5f96-7495-b2bec7f161e8"
              },
              // Observation/mediaChallengeHoldTimesStep3
              {
                "reference" : "Observation/44aa47fd-9964-5f97-6495-b2bec7f161e8"
              },
              // Observation/mediaChallengeBioburden1
              {
                "reference" : "Observation/44aa47fd-8964-5f98-6495-b2bec7f161e8"
              },
              // Observation/mediaChallengeBioburden2
              {
                "reference" : "Observation/44aa47fd-8964-5f99-7495-b2bec7f161e8"
              },
              // Observation/mediaChallengeBioburden3
              {
                "reference" : "Observation/54aa47fd-9964-5f97-6495-b2bec7f161e8"
              },
              // Observation/growthPromotion1
              {
                "reference" : "Observation/64aa47fd-8964-5f98-6495-b2bec7f161e8"
              },
              // Observation/growthPromotion2
              {
                "reference" : "Observation/74aa47fd-8964-5f99-7495-b2bec7f161e8"
              },
              // Observation/growthPromotion3
              {
                "reference" : "Observation/44ba47fd-8964-4f96-6495-b2bec7f161e7"
              },
              // Observation/SE-UHPLCMainPeak1
              {
                "reference" : "Observation/54ca47fd-8964-4f96-6495-b2bec7f162e7"
              },
              // Observation/SE-UHPLCMainPeak2
              {
                "reference" : "Observation/54da48fd-8964-4f96-6495-b2bec7f163e7"
              },
              // Observation/SE-UHPLCMainPeak3
              {
                "reference" : "Observation/44ba47fd-8964-5f96-6495-b2bec7f161e7"
              },
              // Observation/SE-UHPLCMainPeakGraph1
              {
                "reference" : "Observation/44ba47fd-8964-4f97-6495-b2bec7f161e7"
              },
              // Observation/SE-UHPLCHMW1
              {
                "reference" : "Observation/54ca47fd-8964-4f98-6495-b2bec7f162e7"
              },
              // Observation/SE-UHPLCHMW2
              {
                "reference" : "Observation/54da48fd-8964-4f99-6495-b2bec7f163e7"
              },
              // Observation/SE-UHPLCHMW3
              {
                "reference" : "Observation/55aa47fd-9964-5f97-6495-b2bec7f161e8"
              },
              // Observation/fillWeight1
              {
                "reference" : "Observation/45aa47fd-8964-4f96-6495-b2bec7f160f7"
              },
              // Observation/fillingHomogeneityConclusion-nosubject
              {
                "reference" : "Observation/54aa47fd-9964-5f97-6495-b2bec8f161e8"
              },
              // Observation/proteinConcentration1
              {
                "reference" : "Observation/54aa47fd-9964-5f97-6495-b2bec8f162e8"
              },
              // Observation/polysorbate2
              {
                "reference" : "Observation/54aa47fd-9965-5f97-6495-b2bec8f161e8"
              },
              // Observation/proteinConcentrationStats1
              {
                "reference" : "Observation/44ba47fd-8964-4f96-6495-b2bec7f161e8"
              },
              // Observation/residualMoisture1
              {
                "reference" : "Observation/44ba47fd-9964-4f96-6495-b2bec7f161e8"
              },
              // Observation/residualMoisture2
              {
                "reference" : "Observation/44ba47fd-9964-4f96-6496-b2bec7f161e8"
              },
              // Observation/residualMoisture3
              {
                "reference" : "Observation/54ba47fd-8964-4f96-6495-b2bec7f161e7"
              },
              // Observation/SE-UHPLCMainPeakLyoph1
              {
                "reference" : "Observation/54ba47fd-8964-4f96-6495-b2bec7f161e8"
              },
              // Observation/SE-UHPLCMainPeakLyoph2
              {
                "reference" : "Observation/54ba47fd-8964-4f96-6495-b2bec7f161e9"
              },
              // Observation/SE-UHPLCMainPeakLyoph3
              {
                "reference" : "Observation/54ba48fd-8964-4f96-6495-b2bec7f161e7"
              },
              // Observation/SE-UHPLCMainPeakLyophConclusionObs
              {
                "reference" : "Observation/54bb47fd-8964-4f96-6495-b2bec7f161e7"
              },
              // Observation/SE-UHPLCHMWLyoph1
              {
                "reference" : "Observation/54ba47fd-9964-4f96-6495-b2bec7f161e8"
              },
              // Observation/SE-UHPLCHMWLyoph2
              {
                "reference" : "Observation/54ba47fe-8964-4f96-6495-b2bec7f161e9"
              },
              // Observation/SE-UHPLCHMWLyoph3
              {
                "reference" : "Observation/64ba48fd-8964-4f96-6495-b2bec7f161e7"
              }
            ],
            "conclusion" : "The samples have been assessed and the conclusion is..."
          }
        },
        // Observation/SE-UHPLCHMWLyophConclusionObs
        {
          "fullUrl" : "urn:uuid:fd17b5d6-9fe1-91c2-2d06-47cb5b295e72",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "fd17b5d6-9fe1-91c2-2d06-47cb5b295e72",
            "text" : // bufferVesselMixingSpeed
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_fd17b5d6-9fe1-91c2-2d06-47cb5b295e72\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"fd17b5d6-9fe1-91c2-2d06-47cb5b295e72\"> </a><a name=\"hcfd17b5d6-9fe1-91c2-2d06-47cb5b295e72\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;fd17b5d6-9fe1-91c2-2d06-47cb5b295e72&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/fd17b5d6-9fe1-91c2-2d06-47cb5b295e72</code></p><p><b>title</b>: Buffer vessel mixing speed (rpm)</p><p><b>status</b>: active</p><p><b>code</b>: Buffer vessel mixing speed (rpm) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Buffer vessel mixing speed (rpm))</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>150-250 rpm</td></tr></table></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/fd17b5d6-9fe1-91c2-2d06-47cb5b295e72",
            "title" : "Buffer vessel mixing speed (rpm)",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/fd17b5d6-9fe1-91c2-2d06-47cb5b295e72
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Buffer vessel mixing speed (rpm)",
                  "display" : "Buffer vessel mixing speed (rpm)"
                }
              ],
              "text" : "Buffer vessel mixing speed (rpm)"
            },
            "qualifiedValue" : [
              {
                "range" : {
                  "low" : {
                    "value" : 150,
                    "unit" : "rpm"
                  },
                  "high" : {
                    "value" : 250,
                    "unit" : "rpm"
                  }
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:fc17b5d5-9fe1-91c2-2d06-47cb5b295e72",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "fc17b5d5-9fe1-91c2-2d06-47cb5b295e72",
            "text" : // formulationVesselMixingSpeed
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_fc17b5d5-9fe1-91c2-2d06-47cb5b295e72\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"fc17b5d5-9fe1-91c2-2d06-47cb5b295e72\"> </a><a name=\"hcfc17b5d5-9fe1-91c2-2d06-47cb5b295e72\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;fc17b5d5-9fe1-91c2-2d06-47cb5b295e72&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e72</code></p><p><b>title</b>: Formulation vessel mixing speed (rpm)</p><p><b>status</b>: active</p><p><b>code</b>: Formulation vessel mixing speed (rpm) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Formulation vessel mixing speed (rpm))</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>150-250 rpm</td></tr></table></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e72",
            "title" : "Formulation vessel mixing speed (rpm)",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e72
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Formulation vessel mixing speed (rpm)",
                  "display" : "Formulation vessel mixing speed (rpm)"
                }
              ],
              "text" : "Formulation vessel mixing speed (rpm)"
            },
            "qualifiedValue" : [
              {
                "range" : {
                  "low" : {
                    "value" : 150,
                    "unit" : "rpm"
                  },
                  "high" : {
                    "value" : 250,
                    "unit" : "rpm"
                  }
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:fc17b5d5-9fe1-91c2-2d06-47cb5b295e73",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "fc17b5d5-9fe1-91c2-2d06-47cb5b295e73",
            "text" : // bufferVesselMixingTime
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_fc17b5d5-9fe1-91c2-2d06-47cb5b295e73\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"fc17b5d5-9fe1-91c2-2d06-47cb5b295e73\"> </a><a name=\"hcfc17b5d5-9fe1-91c2-2d06-47cb5b295e73\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;fc17b5d5-9fe1-91c2-2d06-47cb5b295e73&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e73</code></p><p><b>title</b>: Buffer vessel mixing time (min)</p><p><b>status</b>: active</p><p><b>code</b>: Buffer vessel mixing time (min) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Buffer vessel mixing time (min))</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>45-55 mins</td></tr></table></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e73",
            "title" : "Buffer vessel mixing time (min)",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e73
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Buffer vessel mixing time (min)",
                  "display" : "Buffer vessel mixing time (min)"
                }
              ],
              "text" : "Buffer vessel mixing time (min)"
            },
            "qualifiedValue" : [
              {
                "range" : {
                  "low" : {
                    "value" : 45,
                    "unit" : "mins",
                    "system" : "http://unitsofmeasure.org",
                    "code" : "min"
                  },
                  "high" : {
                    "value" : 55,
                    "unit" : "mins",
                    "system" : "http://unitsofmeasure.org",
                    "code" : "min"
                  }
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:fc27b5d5-9fe1-92c2-2d06-47cb5b295e73",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "fc27b5d5-9fe1-92c2-2d06-47cb5b295e73",
            "text" : // formulationVesselMixingTime
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_fc27b5d5-9fe1-92c2-2d06-47cb5b295e73\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"fc27b5d5-9fe1-92c2-2d06-47cb5b295e73\"> </a><a name=\"hcfc27b5d5-9fe1-92c2-2d06-47cb5b295e73\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;fc27b5d5-9fe1-92c2-2d06-47cb5b295e73&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/fc27b5d5-9fe1-92c2-2d06-47cb5b295e73</code></p><p><b>title</b>: Formulation vessel mixing time (min)</p><p><b>status</b>: active</p><p><b>code</b>: Formulation vessel mixing time (min) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Formulation vessel mixing time (min))</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>45-55 mins</td></tr></table></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/fc27b5d5-9fe1-92c2-2d06-47cb5b295e73",
            "title" : "Formulation vessel mixing time (min)",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/fc27b5d5-9fe1-92c2-2d06-47cb5b295e73
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Formulation vessel mixing time (min)",
                  "display" : "Formulation vessel mixing time (min)"
                }
              ],
              "text" : "Formulation vessel mixing time (min)"
            },
            "qualifiedValue" : [
              {
                "range" : {
                  "low" : {
                    "value" : 45,
                    "unit" : "mins",
                    "system" : "http://unitsofmeasure.org",
                    "code" : "min"
                  },
                  "high" : {
                    "value" : 55,
                    "unit" : "mins",
                    "system" : "http://unitsofmeasure.org",
                    "code" : "min"
                  }
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:fc27b6d6-9fe2-91c2-2d16-47cb5b295e72",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "fc27b6d6-9fe2-91c2-2d16-47cb5b295e72",
            "text" : // ResidualMoisture
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_fc27b6d6-9fe2-91c2-2d16-47cb5b295e72\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"fc27b6d6-9fe2-91c2-2d16-47cb5b295e72\"> </a><a name=\"hcfc27b6d6-9fe2-91c2-2d16-47cb5b295e72\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;fc27b6d6-9fe2-91c2-2d16-47cb5b295e72&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/fc27b6d6-9fe2-91c2-2d16-47cb5b295e72</code></p><p><b>title</b>: Residual Moisture (%)</p><p><b>status</b>: active</p><p><b>code</b>: ResidualMoisture <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Residual Moisture &quot;Residual Moisture&quot;)</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>?-7.15</td></tr></table><blockquote><p><b>component</b></p><p><b>code</b>: Residual Moisture - Min <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Residual Moisture - Min)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Residual Moisture - Max <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Residual Moisture - Max)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Number of Samples <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SAMP)</span></p></blockquote></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/fc27b6d6-9fe2-91c2-2d16-47cb5b295e72",
            "title" : "Residual Moisture (%)",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/fc27b6d6-9fe2-91c2-2d16-47cb5b295e72
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Residual Moisture",
                  "display" : "Residual Moisture"
                }
              ],
              "text" : "ResidualMoisture"
            },
            "qualifiedValue" : [
              {
                "range" : {
                  "high" : {
                    "value" : 7.15,
                    "unit" : "%",
                    "system" : "http://unitsofmeasure.org",
                    "code" : "%"
                  }
                }
              }
            ],
            "component" : [
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Residual Moisture - Min",
                      "display" : "Residual Moisture - Min"
                    }
                  ]
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Residual Moisture - Max",
                      "display" : "Residual Moisture - Max"
                    }
                  ]
                }
              },
              {
                "code" : //  are expected to have a component that says number of samples
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "SAMP",
                      "display" : "Number of Samples"
                    }
                  ]
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:fc27b5d6-9fe1-91c2-2d16-47cb5b295e72",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "fc27b5d6-9fe1-91c2-2d16-47cb5b295e72",
            "text" : // ThawingFBPPIpH
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_fc27b5d6-9fe1-91c2-2d16-47cb5b295e72\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"fc27b5d6-9fe1-91c2-2d16-47cb5b295e72\"> </a><a name=\"hcfc27b5d6-9fe1-91c2-2d16-47cb5b295e72\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;fc27b5d6-9fe1-91c2-2d16-47cb5b295e72&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/fc27b5d6-9fe1-91c2-2d16-47cb5b295e72</code></p><p><b>title</b>: pH</p><p><b>status</b>: active</p><p><b>code</b>: pH <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#pH)</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>6.55-7.15 pH</td></tr></table></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/fc27b5d6-9fe1-91c2-2d16-47cb5b295e72",
            "title" : "pH",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/fc27b5d6-9fe1-91c2-2d16-47cb5b295e72
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "pH",
                  "display" : "pH"
                }
              ],
              "text" : "pH"
            },
            "qualifiedValue" : [
              {
                "range" : {
                  "low" : {
                    "value" : 6.55,
                    "unit" : "pH",
                    "system" : "http://unitsofmeasure.org",
                    "code" : "pH"
                  },
                  "high" : {
                    "value" : 7.15,
                    "unit" : "pH",
                    "system" : "http://unitsofmeasure.org",
                    "code" : "pH"
                  }
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:fc27b5d6-9fe2-91c2-2d16-47cb5b295e72",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "fc27b5d6-9fe2-91c2-2d16-47cb5b295e72",
            "text" : // ThawingTime
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_fc27b5d6-9fe2-91c2-2d16-47cb5b295e72\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"fc27b5d6-9fe2-91c2-2d16-47cb5b295e72\"> </a><a name=\"hcfc27b5d6-9fe2-91c2-2d16-47cb5b295e72\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;fc27b5d6-9fe2-91c2-2d16-47cb5b295e72&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/fc27b5d6-9fe2-91c2-2d16-47cb5b295e72</code></p><p><b>title</b>: Thaw Time</p><p><b>status</b>: active</p><p><b>code</b>: Thaw Time (hr) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Thaw Time &quot;Thaw Time&quot;)</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>?-3</td></tr></table></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/fc27b5d6-9fe2-91c2-2d16-47cb5b295e72",
            "title" : "Thaw Time",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/fc27b5d6-9fe2-91c2-2d16-47cb5b295e72
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Thaw Time",
                  "display" : "Thaw Time"
                }
              ],
              "text" : "Thaw Time (hr)"
            },
            "qualifiedValue" : [
              {
                "range" : {
                  "high" : {
                    "value" : 3,
                    "unit" : "hour",
                    "system" : "http://unitsofmeasure.org",
                    "code" : "h"
                  }
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:fc17b5d6-9fe1-91c2-2d16-47cb5b295e72",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "fc17b5d6-9fe1-91c2-2d16-47cb5b295e72",
            "text" : // FBPPIpH
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_fc17b5d6-9fe1-91c2-2d16-47cb5b295e72\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"fc17b5d6-9fe1-91c2-2d16-47cb5b295e72\"> </a><a name=\"hcfc17b5d6-9fe1-91c2-2d16-47cb5b295e72\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;fc17b5d6-9fe1-91c2-2d16-47cb5b295e72&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/fc17b5d6-9fe1-91c2-2d16-47cb5b295e72</code></p><p><b>title</b>: pH</p><p><b>status</b>: active</p><p><b>code</b>: pH <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#pH)</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>6.95-7.05 pH</td></tr></table></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/fc17b5d6-9fe1-91c2-2d16-47cb5b295e72",
            "title" : "pH",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/fc17b5d6-9fe1-91c2-2d16-47cb5b295e72
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "pH",
                  "display" : "pH"
                }
              ],
              "text" : "pH"
            },
            "qualifiedValue" : [
              {
                "range" : {
                  "low" : {
                    "value" : 6.95,
                    "unit" : "pH",
                    "system" : "http://unitsofmeasure.org",
                    "code" : "pH"
                  },
                  "high" : {
                    "value" : 7.05,
                    "unit" : "pH",
                    "system" : "http://unitsofmeasure.org",
                    "code" : "pH"
                  }
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:64525a3c-5034-448a-9c19-938ce1958424",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "64525a3c-5034-448a-9c19-938ce1958424",
            "text" : // Osmolality
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_64525a3c-5034-448a-9c19-938ce1958424\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"64525a3c-5034-448a-9c19-938ce1958424\"> </a><a name=\"hc64525a3c-5034-448a-9c19-938ce1958424\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;64525a3c-5034-448a-9c19-938ce1958424&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/64525a3c-5034-448a-9c19-938ce1958424</code></p><p><b>title</b>: Osmolality</p><p><b>status</b>: active</p><p><b>code</b>: Osmolality (mOsm/kg) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Osmolality &quot;Osmolality&quot;)</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>250-300 mOsm/kg</td></tr></table></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/64525a3c-5034-448a-9c19-938ce1958424",
            "title" : "Osmolality",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/64525a3c-5034-448a-9c19-938ce1958424
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Osmolality",
                  "display" : "Osmolality"
                }
              ],
              "text" : "Osmolality (mOsm/kg)"
            },
            "qualifiedValue" : [
              {
                "range" : {
                  "low" : //  todo UCUM
                  {
                    "value" : 250,
                    "unit" : "mOsm/kg"
                  },
                  "high" : //  todo UCUM
                  {
                    "value" : 300,
                    "unit" : "mOsm/kg"
                  }
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:64525a3d-5134-448a-9c19-938ce1958424",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "64525a3d-5134-448a-9c19-938ce1958424",
            "text" : // SE-UHPLCMainPeakLyoph
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_64525a3d-5134-448a-9c19-938ce1958424\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"64525a3d-5134-448a-9c19-938ce1958424\"> </a><a name=\"hc64525a3d-5134-448a-9c19-938ce1958424\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;64525a3d-5134-448a-9c19-938ce1958424&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/64525a3d-5134-448a-9c19-938ce1958424</code></p><p><b>title</b>: SE-UHPLC Main Peak</p><p><b>status</b>: active</p><p><b>code</b>: SE-UHPLC Main Peak (%) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SE-UHPLCMainPeak &quot;SE-UHPLC Main Peak&quot;)</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td/><td>85-95 %</td></tr></table><blockquote><p><b>component</b></p><p><b>code</b>: SE-UHPLC Main Peak - Conclusion <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SE-UHPLC Main Peak - Conclusion)</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td></tr><tr><td style=\"display: none\">*</td><td/></tr></table></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Number of Samples <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#OVERALLSAMP)</span></p></blockquote></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/64525a3d-5134-448a-9c19-938ce1958424",
            "title" : "SE-UHPLC Main Peak",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/64525a3d-5134-448a-9c19-938ce1958424
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "SE-UHPLCMainPeak",
                  "display" : "SE-UHPLC Main Peak"
                }
              ],
              "text" : "SE-UHPLC Main Peak (%)"
            },
            "qualifiedValue" : [
              {
                "extension" : [
                  {
                    "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-display-pq",
                    "valueString" : "± 5% target"
                  }
                ],
                "range" : {
                  "low" : //  todo UCUM
                  {
                    "value" : 85,
                    "unit" : "%"
                  },
                  "high" : //  todo UCUM
                  {
                    "value" : 95,
                    "unit" : "%"
                  }
                }
              }
            ],
            "component" : [
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "SE-UHPLC Main Peak - Conclusion",
                      "display" : "SE-UHPLC Main Peak - Conclusion"
                    }
                  ]
                },
                "qualifiedValue" : [
                  {
                    "extension" : [
                      {
                        "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-text-pq",
                        "valueString" : "Pass"
                      }
                    ]
                  }
                ]
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "OVERALLSAMP",
                      "display" : "Number of Samples"
                    }
                  ]
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:64525a3d-5144-448a-9c19-938ce1958424",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "64525a3d-5144-448a-9c19-938ce1958424",
            "text" : // SE-UHPLCHMWLyoph
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_64525a3d-5144-448a-9c19-938ce1958424\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"64525a3d-5144-448a-9c19-938ce1958424\"> </a><a name=\"hc64525a3d-5144-448a-9c19-938ce1958424\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;64525a3d-5144-448a-9c19-938ce1958424&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/64525a3d-5144-448a-9c19-938ce1958424</code></p><p><b>title</b>: SE-UHPLC HMW</p><p><b>status</b>: active</p><p><b>code</b>: SE-UHPLC HMW (%) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SE-UHPLCHMW &quot;SE-UHPLC HMW&quot;)</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td/><td>88-92 %</td></tr></table><blockquote><p><b>component</b></p><p><b>code</b>: SE-UHPLC HMW - Conclusion <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SE-UHPLC HMW - Conclusion)</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td></tr><tr><td style=\"display: none\">*</td><td/></tr></table></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Number of Samples <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#OVERALLSAMP)</span></p></blockquote></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/64525a3d-5144-448a-9c19-938ce1958424",
            "title" : "SE-UHPLC HMW",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/64525a3d-5144-448a-9c19-938ce1958424
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "SE-UHPLCHMW",
                  "display" : "SE-UHPLC HMW"
                }
              ],
              "text" : "SE-UHPLC HMW (%)"
            },
            "qualifiedValue" : [
              {
                "extension" : [
                  {
                    "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-display-pq",
                    "valueString" : "± 2% target"
                  }
                ],
                "range" : {
                  "low" : //  todo UCUM
                  {
                    "value" : 88,
                    "unit" : "%"
                  },
                  "high" : //  todo UCUM
                  {
                    "value" : 92,
                    "unit" : "%"
                  }
                }
              }
            ],
            "component" : [
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "SE-UHPLC HMW - Conclusion",
                      "display" : "SE-UHPLC HMW - Conclusion"
                    }
                  ]
                },
                "qualifiedValue" : [
                  {
                    "extension" : [
                      {
                        "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-text-pq",
                        "valueString" : "Pass"
                      }
                    ]
                  }
                ]
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "OVERALLSAMP",
                      "display" : "Number of Samples"
                    }
                  ]
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:64525a3d-5034-448a-9c19-938ce1958424",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "64525a3d-5034-448a-9c19-938ce1958424",
            "text" : // SE-UHPLCMainPeak
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_64525a3d-5034-448a-9c19-938ce1958424\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"64525a3d-5034-448a-9c19-938ce1958424\"> </a><a name=\"hc64525a3d-5034-448a-9c19-938ce1958424\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;64525a3d-5034-448a-9c19-938ce1958424&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/64525a3d-5034-448a-9c19-938ce1958424</code></p><p><b>title</b>: SE-UHPLC Main Peak</p><p><b>status</b>: active</p><p><b>code</b>: SE-UHPLC Main Peak (%) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SE-UHPLCMainPeak &quot;SE-UHPLC Main Peak&quot;)</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>5-? %</td></tr></table></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/64525a3d-5034-448a-9c19-938ce1958424",
            "title" : "SE-UHPLC Main Peak",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/64525a3d-5034-448a-9c19-938ce1958424
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "SE-UHPLCMainPeak",
                  "display" : "SE-UHPLC Main Peak"
                }
              ],
              "text" : "SE-UHPLC Main Peak (%)"
            },
            "qualifiedValue" : [
              {
                "range" : {
                  "low" : //  todo UCUM
                  {
                    "value" : 5,
                    "unit" : "%"
                  }
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:64525a4d-5034-448a-9c19-938ce1958424",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "64525a4d-5034-448a-9c19-938ce1958424",
            "text" : // SE-UHPLCMainPeakGraph
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_64525a4d-5034-448a-9c19-938ce1958424\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"64525a4d-5034-448a-9c19-938ce1958424\"> </a><a name=\"hc64525a4d-5034-448a-9c19-938ce1958424\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;64525a4d-5034-448a-9c19-938ce1958424&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/64525a4d-5034-448a-9c19-938ce1958424</code></p><p><b>title</b>: SE-UHPLC Main Peak Graph</p><p><b>status</b>: active</p><p><b>code</b>: SE-UHPLC Main Peak (graph) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SE-UHPLCMainPeak &quot;SE-UHPLC Main Peak&quot;)</span></p></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/64525a4d-5034-448a-9c19-938ce1958424",
            "title" : "SE-UHPLC Main Peak Graph",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/64525a4d-5034-448a-9c19-938ce1958424
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "SE-UHPLCMainPeak",
                  "display" : "SE-UHPLC Main Peak"
                }
              ],
              "text" : "SE-UHPLC Main Peak (graph)"
            }
          }
        },
        {
          "fullUrl" : "urn:uuid:64525a33-5034-448a-9c19-938ce1958424",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "64525a33-5034-448a-9c19-938ce1958424",
            "text" : // SE-UHPLCHMW
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_64525a33-5034-448a-9c19-938ce1958424\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"64525a33-5034-448a-9c19-938ce1958424\"> </a><a name=\"hc64525a33-5034-448a-9c19-938ce1958424\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;64525a33-5034-448a-9c19-938ce1958424&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/64525a33-5034-448a-9c19-938ce1958424</code></p><p><b>title</b>: SE-UHPLC HMW</p><p><b>status</b>: active</p><p><b>code</b>: SE-UHPLC HMW (%) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SE-UHPLCHMW &quot;SE-UHPLC HMW&quot;)</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>7-? %</td></tr></table></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/64525a33-5034-448a-9c19-938ce1958424",
            "title" : "SE-UHPLC HMW",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/64525a33-5034-448a-9c19-938ce1958424
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "SE-UHPLCHMW",
                  "display" : "SE-UHPLC HMW"
                }
              ],
              "text" : "SE-UHPLC HMW (%)"
            },
            "qualifiedValue" : [
              {
                "range" : {
                  "low" : //  todo UCUM
                  {
                    "value" : 7,
                    "unit" : "%"
                  }
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:22515a3c-5034-448a-9c19-938ce1958424",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "22515a3c-5034-448a-9c19-938ce1958424",
            "text" : // conclusion
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_22515a3c-5034-448a-9c19-938ce1958424\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"22515a3c-5034-448a-9c19-938ce1958424\"> </a><a name=\"hc22515a3c-5034-448a-9c19-938ce1958424\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;22515a3c-5034-448a-9c19-938ce1958424&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/22515a3c-5034-448a-9c19-938ce1958424</code></p><p><b>title</b>: Conclusion</p><p><b>status</b>: active</p><p><b>code</b>: Conclusion <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#CONC)</span></p></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/22515a3c-5034-448a-9c19-938ce1958424",
            "title" : "Conclusion",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/22515a3c-5034-448a-9c19-938ce1958424
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "CONC",
                  "display" : "Conclusion"
                }
              ],
              "text" : "Conclusion"
            }
          }
        },
        {
          "fullUrl" : "urn:uuid:22525a3c-5035-448a-9c19-938ce1958424",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "22525a3c-5035-448a-9c19-938ce1958424",
            "text" : // conclusionHomogeneity
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_22525a3c-5035-448a-9c19-938ce1958424\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"22525a3c-5035-448a-9c19-938ce1958424\"> </a><a name=\"hc22525a3c-5035-448a-9c19-938ce1958424\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;22525a3c-5035-448a-9c19-938ce1958424&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/22525a3c-5035-448a-9c19-938ce1958424</code></p><p><b>title</b>: Conclusion</p><p><b>status</b>: active</p><p><b>code</b>: Conclusion <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#CONC)</span></p></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/22525a3c-5035-448a-9c19-938ce1958424",
            "title" : "Conclusion",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/22525a3c-5035-448a-9c19-938ce1958424
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "CONC",
                  "display" : "Conclusion"
                }
              ],
              "text" : "Conclusion"
            }
          }
        },
        {
          "fullUrl" : "urn:uuid:64515a3c-5034-448a-9c19-938ce1958424",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "64515a3c-5034-448a-9c19-938ce1958424",
            "text" : // ThawingOsmolality
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_64515a3c-5034-448a-9c19-938ce1958424\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"64515a3c-5034-448a-9c19-938ce1958424\"> </a><a name=\"hc64515a3c-5034-448a-9c19-938ce1958424\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;64515a3c-5034-448a-9c19-938ce1958424&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/64515a3c-5034-448a-9c19-938ce1958424</code></p><p><b>title</b>: Osmolality</p><p><b>status</b>: active</p><p><b>code</b>: Osmolality (mOsm/kg) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Osmolality &quot;Osmolality&quot;)</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>240-310 mOsm/kg</td></tr></table></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/64515a3c-5034-448a-9c19-938ce1958424",
            "title" : "Osmolality",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/64515a3c-5034-448a-9c19-938ce1958424
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Osmolality",
                  "display" : "Osmolality"
                }
              ],
              "text" : "Osmolality (mOsm/kg)"
            },
            "qualifiedValue" : [
              {
                "range" : {
                  "low" : //  todo UCUM
                  {
                    "value" : 240,
                    "unit" : "mOsm/kg"
                  },
                  "high" : //  todo UCUM
                  {
                    "value" : 310,
                    "unit" : "mOsm/kg"
                  }
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:74515a3c-5034-448a-9c19-938ce1958424",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "74515a3c-5034-448a-9c19-938ce1958424",
            "text" : // ThawingTemp
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_74515a3c-5034-448a-9c19-938ce1958424\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"74515a3c-5034-448a-9c19-938ce1958424\"> </a><a name=\"hc74515a3c-5034-448a-9c19-938ce1958424\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;74515a3c-5034-448a-9c19-938ce1958424&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/74515a3c-5034-448a-9c19-938ce1958424</code></p><p><b>title</b>: Thawing Temp</p><p><b>status</b>: active</p><p><b>code</b>: Thawing Temp (°C) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Thawing Temp &quot;Thawing Temp&quot;)</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>20-24 °C</td></tr></table></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/74515a3c-5034-448a-9c19-938ce1958424",
            "title" : "Thawing Temp",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/74515a3c-5034-448a-9c19-938ce1958424
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Thawing Temp",
                  "display" : "Thawing Temp"
                }
              ],
              "text" : "Thawing Temp (°C)"
            },
            "qualifiedValue" : [
              {
                "range" : {
                  "low" : //  todo UCUM
                  {
                    "value" : 20,
                    "unit" : "°C"
                  },
                  "high" : //  todo UCUM
                  {
                    "value" : 24,
                    "unit" : "°C"
                  }
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:64515a3c-5134-448a-9c19-939ce1958424",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "64515a3c-5134-448a-9c19-939ce1958424",
            "text" : // Conductivity
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_64515a3c-5134-448a-9c19-939ce1958424\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"64515a3c-5134-448a-9c19-939ce1958424\"> </a><a name=\"hc64515a3c-5134-448a-9c19-939ce1958424\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;64515a3c-5134-448a-9c19-939ce1958424&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/64515a3c-5134-448a-9c19-939ce1958424</code></p><p><b>title</b>: Conductivity</p><p><b>status</b>: active</p><p><b>code</b>: Conductivity (μS/cm) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Conductivity (μS/cm))</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>150-200 μS/cm</td></tr></table></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/64515a3c-5134-448a-9c19-939ce1958424",
            "title" : "Conductivity",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/64515a3c-5134-448a-9c19-939ce1958424
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Conductivity (μS/cm)",
                  "display" : "Conductivity (μS/cm)"
                }
              ]
            },
            "qualifiedValue" : [
              {
                "range" : {
                  "low" : //  todo UCUM
                  {
                    "value" : 150,
                    "unit" : "μS/cm"
                  },
                  "high" : //  todo UCUM
                  {
                    "value" : 200,
                    "unit" : "μS/cm"
                  }
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:74515a3c-5134-448a-9c19-939ce1958424",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "74515a3c-5134-448a-9c19-939ce1958424",
            "text" : // ThawingConductivity
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_74515a3c-5134-448a-9c19-939ce1958424\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"74515a3c-5134-448a-9c19-939ce1958424\"> </a><a name=\"hc74515a3c-5134-448a-9c19-939ce1958424\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;74515a3c-5134-448a-9c19-939ce1958424&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/74515a3c-5134-448a-9c19-939ce1958424</code></p><p><b>title</b>: Conductivity</p><p><b>status</b>: active</p><p><b>code</b>: Conductivity (μS/cm) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Conductivity (μS/cm))</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>150-200 μS/cm</td></tr></table></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/74515a3c-5134-448a-9c19-939ce1958424",
            "title" : "Conductivity",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/74515a3c-5134-448a-9c19-939ce1958424
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Conductivity (μS/cm)",
                  "display" : "Conductivity (μS/cm)"
                }
              ]
            },
            "qualifiedValue" : [
              {
                "range" : {
                  "low" : //  todo UCUM
                  {
                    "value" : 150,
                    "unit" : "μS/cm"
                  },
                  "high" : //  todo UCUM
                  {
                    "value" : 200,
                    "unit" : "μS/cm"
                  }
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:64515b3c-5134-448a-9c19-939ce1958424",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "64515b3c-5134-448a-9c19-939ce1958424",
            "text" : // Bioburden
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_64515b3c-5134-448a-9c19-939ce1958424\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"64515b3c-5134-448a-9c19-939ce1958424\"> </a><a name=\"hc64515b3c-5134-448a-9c19-939ce1958424\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;64515b3c-5134-448a-9c19-939ce1958424&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9c19-939ce1958424</code></p><p><b>title</b>: Bioburden</p><p><b>status</b>: active</p><p><b>code</b>: Bioburden (CFU/ 100 mL) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Bioburden (CFU/ 100 mL))</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>50-150 CFU/ 100 mL</td></tr></table></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9c19-939ce1958424",
            "title" : "Bioburden",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9c19-939ce1958424
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Bioburden (CFU/ 100 mL)",
                  "display" : "Bioburden (CFU/ 100 mL)"
                }
              ]
            },
            "qualifiedValue" : [
              {
                "range" : {
                  "low" : //  todo UCUM
                  {
                    "value" : 50,
                    "unit" : "CFU/ 100 mL"
                  },
                  "high" : //  todo UCUM
                  {
                    "value" : 150,
                    "unit" : "CFU/ 100 mL"
                  }
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:64515b3c-5134-448a-9c19-939ce1958524",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "64515b3c-5134-448a-9c19-939ce1958524",
            "text" : // MediaBioburden
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_64515b3c-5134-448a-9c19-939ce1958524\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"64515b3c-5134-448a-9c19-939ce1958524\"> </a><a name=\"hc64515b3c-5134-448a-9c19-939ce1958524\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;64515b3c-5134-448a-9c19-939ce1958524&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9c19-939ce1958524</code></p><p><b>title</b>: Bioburden</p><p><b>status</b>: active</p><p><b>code</b>: Bioburden (CFU/ 100 mL) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Bioburden (CFU/ 100 mL))</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>?-10</td></tr></table><blockquote><p><b>component</b></p><p><b>code</b>: Bioburden - Beginning <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Bioburden - Beginning)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Bioburden - End <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Bioburden - End)</span></p></blockquote></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9c19-939ce1958524",
            "title" : "Bioburden",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9c19-939ce1958524
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Bioburden (CFU/ 100 mL)",
                  "display" : "Bioburden (CFU/ 100 mL)"
                }
              ]
            },
            "qualifiedValue" : [
              {
                "range" : {
                  "high" : //  todo UCUM
                  {
                    "value" : 10,
                    "unit" : "CFU/100 mL"
                  }
                }
              }
            ],
            "component" : [
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Bioburden - Beginning",
                      "display" : "Bioburden - Beginning"
                    }
                  ]
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Bioburden - End",
                      "display" : "Bioburden - End"
                    }
                  ]
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:74515b3c-5234-448a-9c19-939ce1958524",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "74515b3c-5234-448a-9c19-939ce1958524",
            "text" : // Polysorbate80Concentration
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_74515b3c-5234-448a-9c19-939ce1958524\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"74515b3c-5234-448a-9c19-939ce1958524\"> </a><a name=\"hc74515b3c-5234-448a-9c19-939ce1958524\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;74515b3c-5234-448a-9c19-939ce1958524&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/74515b3c-5234-448a-9c19-939ce1958524</code></p><p><b>title</b>: Polysorbate 80 Concentration</p><p><b>status</b>: active</p><p><b>code</b>: Polysorbate 80 concentration - Middle - Max <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Polysorbate 80 concentration - Middle - Max)</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>0.5-1.5 % w/v</td></tr></table><blockquote><p><b>component</b></p><p><b>code</b>: Polysorbate 80 concentration - Beginning - Min <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Polysorbate 80 concentration - Beginning - Min)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Polysorbate 80 concentration - Beginning - Max <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Polysorbate 80 concentration - Beginning - Max)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Polysorbate 80 concentration - Middle - Min <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Polysorbate 80 concentration - Middle - Min)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Polysorbate 80 concentration - Middle - Max <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Polysorbate 80 concentration - Middle - Max)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Polysorbate 80 concentration - End - Min <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Polysorbate 80 concentration - End - Min)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Polysorbate 80 concentration - End - Max <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Polysorbate 80 concentration - End - Max)</span></p></blockquote></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/74515b3c-5234-448a-9c19-939ce1958524",
            "title" : "Polysorbate 80 Concentration",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/74515b3c-5234-448a-9c19-939ce1958524
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Polysorbate 80 concentration - Middle - Max",
                  "display" : "Polysorbate 80 concentration - Middle - Max"
                }
              ]
            },
            "qualifiedValue" : [
              {
                "range" : {
                  "low" : //  todo UCUM
                  {
                    "value" : 0.5,
                    "unit" : "% w/v"
                  },
                  "high" : //  todo UCUM
                  {
                    "value" : 1.5,
                    "unit" : "% w/v"
                  }
                }
              }
            ],
            "component" : [
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Polysorbate 80 concentration - Beginning - Min",
                      "display" : "Polysorbate 80 concentration - Beginning - Min"
                    }
                  ]
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Polysorbate 80 concentration - Beginning - Max",
                      "display" : "Polysorbate 80 concentration - Beginning - Max"
                    }
                  ]
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Polysorbate 80 concentration - Middle - Min",
                      "display" : "Polysorbate 80 concentration - Middle - Min"
                    }
                  ]
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Polysorbate 80 concentration - Middle - Max",
                      "display" : "Polysorbate 80 concentration - Middle - Max"
                    }
                  ]
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Polysorbate 80 concentration - End - Min",
                      "display" : "Polysorbate 80 concentration - End - Min"
                    }
                  ]
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Polysorbate 80 concentration - End - Max",
                      "display" : "Polysorbate 80 concentration - End - Max"
                    }
                  ]
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:74515b3c-5134-448a-9c19-939ce1958524",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "74515b3c-5134-448a-9c19-939ce1958524",
            "text" : // ProteinConcentration
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_74515b3c-5134-448a-9c19-939ce1958524\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"74515b3c-5134-448a-9c19-939ce1958524\"> </a><a name=\"hc74515b3c-5134-448a-9c19-939ce1958524\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;74515b3c-5134-448a-9c19-939ce1958524&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/74515b3c-5134-448a-9c19-939ce1958524</code></p><p><b>title</b>: Protein Concentration</p><p><b>status</b>: active</p><p><b>code</b>: Protein Concentration (mg/mL) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Protein Concentration (mg/mL))</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>8-10 (mg/mL)</td></tr></table><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Beginning - Min <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Protein Concentration - Beginning - Min)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Beginning - Max <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Protein Concentration - Beginning - Max)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Middle - Min <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Protein Concentration - Middle - Min)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Middle - Max <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Protein Concentration - Middle - Max)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - End - Min <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Protein Concentration - End - Min)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - End - Max <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Protein Concentration - End - Max)</span></p></blockquote></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/74515b3c-5134-448a-9c19-939ce1958524",
            "title" : "Protein Concentration",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/74515b3c-5134-448a-9c19-939ce1958524
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Protein Concentration (mg/mL)",
                  "display" : "Protein Concentration (mg/mL)"
                }
              ]
            },
            "qualifiedValue" : [
              {
                "range" : {
                  "low" : //  todo UCUM
                  {
                    "value" : 8,
                    "unit" : "(mg/mL)"
                  },
                  "high" : //  todo UCUM
                  {
                    "value" : 10,
                    "unit" : "(mg/mL)"
                  }
                }
              }
            ],
            "component" : [
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Protein Concentration - Beginning - Min",
                      "display" : "Protein Concentration - Beginning - Min"
                    }
                  ]
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Protein Concentration - Beginning - Max",
                      "display" : "Protein Concentration - Beginning - Max"
                    }
                  ]
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Protein Concentration - Middle - Min",
                      "display" : "Protein Concentration - Middle - Min"
                    }
                  ]
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Protein Concentration - Middle - Max",
                      "display" : "Protein Concentration - Middle - Max"
                    }
                  ]
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Protein Concentration - End - Min",
                      "display" : "Protein Concentration - End - Min"
                    }
                  ]
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Protein Concentration - End - Max",
                      "display" : "Protein Concentration - End - Max"
                    }
                  ]
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:74515b3c-5134-448a-9c19-939ce1958534",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "74515b3c-5134-448a-9c19-939ce1958534",
            "text" : // ProteinConcentrationStats
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_74515b3c-5134-448a-9c19-939ce1958534\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"74515b3c-5134-448a-9c19-939ce1958534\"> </a><a name=\"hc74515b3c-5134-448a-9c19-939ce1958534\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;74515b3c-5134-448a-9c19-939ce1958534&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/74515b3c-5134-448a-9c19-939ce1958534</code></p><p><b>title</b>: Protein Concentration Stats</p><p><b>status</b>: active</p><p><b>code</b>: Protein Concentration Statistics <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Protein Concentration Statistics)</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>8-10 (mg/mL)</td></tr></table><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Beginning - Middle - Mean <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Protein Concentration - Beginning - Middle - Mean)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Beginning - End - Mean <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Protein Concentration - Beginning - End - Mean)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Middle - End - Mean <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Protein Concentration - Middle - End - Mean)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Beginning - Middle - Lower <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Protein Concentration - Beginning - Middle - Lower)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Beginning - End - Lower <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Protein Concentration - Beginning - End - Lower)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Middle - End - Lower <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Protein Concentration - Middle - End - Lower)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Beginning - Middle - Higher <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Protein Concentration - Beginning - Middle - Higher)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Beginning - End - Higher <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Protein Concentration - Beginning - End - Higher)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Middle - End - Higher <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Protein Concentration - Middle - End - Higher)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Conclusion <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Protein Concentration - Conclusion)</span></p></blockquote></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/74515b3c-5134-448a-9c19-939ce1958534",
            "title" : "Protein Concentration Stats",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/74515b3c-5134-448a-9c19-939ce1958534
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Protein Concentration Statistics",
                  "display" : "Protein Concentration Statistics"
                }
              ]
            },
            "qualifiedValue" : [
              {
                "range" : {
                  "low" : //  todo UCUM
                  {
                    "value" : 8,
                    "unit" : "(mg/mL)"
                  },
                  "high" : //  todo UCUM
                  {
                    "value" : 10,
                    "unit" : "(mg/mL)"
                  }
                }
              }
            ],
            "component" : [
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Protein Concentration - Beginning - Middle - Mean",
                      "display" : "Protein Concentration - Beginning - Middle - Mean"
                    }
                  ]
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Protein Concentration - Beginning - End - Mean",
                      "display" : "Protein Concentration - Beginning - End - Mean"
                    }
                  ]
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Protein Concentration - Middle - End - Mean",
                      "display" : "Protein Concentration - Middle - End - Mean"
                    }
                  ]
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Protein Concentration - Beginning - Middle - Lower",
                      "display" : "Protein Concentration - Beginning - Middle - Lower"
                    }
                  ]
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Protein Concentration - Beginning - End - Lower",
                      "display" : "Protein Concentration - Beginning - End - Lower"
                    }
                  ]
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Protein Concentration - Middle - End - Lower",
                      "display" : "Protein Concentration - Middle - End - Lower"
                    }
                  ]
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Protein Concentration - Beginning - Middle - Higher",
                      "display" : "Protein Concentration - Beginning - Middle - Higher"
                    }
                  ]
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Protein Concentration - Beginning - End - Higher",
                      "display" : "Protein Concentration - Beginning - End - Higher"
                    }
                  ]
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Protein Concentration - Middle - End - Higher",
                      "display" : "Protein Concentration - Middle - End - Higher"
                    }
                  ]
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Protein Concentration - Conclusion",
                      "display" : "Protein Concentration - Conclusion"
                    }
                  ]
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:64515b3c-5134-448a-9c19-939ce2958524",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "64515b3c-5134-448a-9c19-939ce2958524",
            "text" : // FillWeight
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_64515b3c-5134-448a-9c19-939ce2958524\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"64515b3c-5134-448a-9c19-939ce2958524\"> </a><a name=\"hc64515b3c-5134-448a-9c19-939ce2958524\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;64515b3c-5134-448a-9c19-939ce2958524&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9c19-939ce2958524</code></p><p><b>title</b>: Fill Weight</p><p><b>status</b>: active</p><p><b>code</b>: Fill Weight <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Fill Weight)</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td/><td>95-105 g</td></tr></table><blockquote><p><b>component</b></p><p><b>code</b>: Bioburden - Beginning <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Bioburden - Beginning)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Bioburden - End <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Bioburden - End)</span></p></blockquote></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9c19-939ce2958524",
            "title" : "Fill Weight",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9c19-939ce2958524
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Fill Weight",
                  "display" : "Fill Weight"
                }
              ]
            },
            "qualifiedValue" : [
              {
                "extension" : [
                  {
                    "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-target-pq",
                    "valueQuantity" : //  todo UCUM
                    {
                      "value" : 100,
                      "unit" : "g"
                    }
                  }
                ],
                "range" : {
                  "low" : //  todo UCUM
                  {
                    "value" : 95,
                    "unit" : "g"
                  },
                  "high" : //  todo UCUM
                  {
                    "value" : 105,
                    "unit" : "g"
                  }
                }
              }
            ],
            "component" : [
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Bioburden - Beginning",
                      "display" : "Bioburden - Beginning"
                    }
                  ]
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Bioburden - End",
                      "display" : "Bioburden - End"
                    }
                  ]
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:64515b3c-5134-448a-9d19-939ce1958524",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "64515b3c-5134-448a-9d19-939ce1958524",
            "text" : // GrowthPromotion
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_64515b3c-5134-448a-9d19-939ce1958524\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"64515b3c-5134-448a-9d19-939ce1958524\"> </a><a name=\"hc64515b3c-5134-448a-9d19-939ce1958524\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;64515b3c-5134-448a-9d19-939ce1958524&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9d19-939ce1958524</code></p><p><b>title</b>: Growth Promotion</p><p><b>status</b>: active</p><p><b>code</b>: Growth Promotion <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#GrowthPromotion)</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td></tr><tr><td style=\"display: none\">*</td><td/></tr></table><blockquote><p><b>component</b></p><p><b>code</b>: Growth Promotion - Beginning <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Growth Promotion - Beginning)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Growth Promotion - End <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Growth Promotion - End)</span></p></blockquote></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9d19-939ce1958524",
            "title" : "Growth Promotion",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9d19-939ce1958524
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "GrowthPromotion",
                  "display" : "Growth Promotion"
                }
              ]
            },
            "qualifiedValue" : [
              {
                "extension" : [
                  {
                    "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-text-pq",
                    "valueString" : "Pass"
                  }
                ]
              }
            ],
            "component" : [
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Growth Promotion - Beginning",
                      "display" : "Growth Promotion - Beginning"
                    }
                  ]
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Growth Promotion - End",
                      "display" : "Growth Promotion - End"
                    }
                  ]
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:64515b3c-5134-448a-9c19-939ce1958434",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "64515b3c-5134-448a-9c19-939ce1958434",
            "text" : // PreFiltrationBioburden
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_64515b3c-5134-448a-9c19-939ce1958434\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"64515b3c-5134-448a-9c19-939ce1958434\"> </a><a name=\"hc64515b3c-5134-448a-9c19-939ce1958434\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;64515b3c-5134-448a-9c19-939ce1958434&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9c19-939ce1958434</code></p><p><b>title</b>: Pre-filtration Bioburden</p><p><b>status</b>: active</p><p><b>code</b>: Pre-filtration Bioburden (CFU/ 100 mL) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Pre-filtration Bioburden (CFU/ 100 mL))</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>?-150</td></tr></table></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9c19-939ce1958434",
            "title" : "Pre-filtration Bioburden",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9c19-939ce1958434
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Pre-filtration Bioburden (CFU/ 100 mL)",
                  "display" : "Pre-filtration Bioburden (CFU/ 100 mL)"
                }
              ]
            },
            "qualifiedValue" : [
              {
                "range" : {
                  "high" : //  todo UCUM
                  {
                    "value" : 150,
                    "unit" : "CFU/ 100 mL"
                  }
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:64515b3c-5134-448a-9c19-949ce1958424",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "64515b3c-5134-448a-9c19-949ce1958424",
            "text" : // BacterialEndotoxins
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_64515b3c-5134-448a-9c19-949ce1958424\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"64515b3c-5134-448a-9c19-949ce1958424\"> </a><a name=\"hc64515b3c-5134-448a-9c19-949ce1958424\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;64515b3c-5134-448a-9c19-949ce1958424&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9c19-949ce1958424</code></p><p><b>title</b>: Bacterial Endotoxins</p><p><b>status</b>: active</p><p><b>code</b>: Bacterial Endotoxins (EU/mL) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Bacterial Endotoxins (EU/mL))</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>40-120 EU/mL</td></tr></table></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9c19-949ce1958424",
            "title" : "Bacterial Endotoxins",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9c19-949ce1958424
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Bacterial Endotoxins (EU/mL)",
                  "display" : "Bacterial Endotoxins (EU/mL)"
                }
              ]
            },
            "qualifiedValue" : [
              {
                "range" : {
                  "low" : //  todo UCUM
                  {
                    "value" : 40,
                    "unit" : "EU/mL"
                  },
                  "high" : //  todo UCUM
                  {
                    "value" : 120,
                    "unit" : "EU/mL"
                  }
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:64515b4c-5134-448a-9c19-949ce1958424",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "64515b4c-5134-448a-9c19-949ce1958424",
            "text" : // ThawingBacterialEndotoxins
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_64515b4c-5134-448a-9c19-949ce1958424\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"64515b4c-5134-448a-9c19-949ce1958424\"> </a><a name=\"hc64515b4c-5134-448a-9c19-949ce1958424\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;64515b4c-5134-448a-9c19-949ce1958424&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/64515b4c-5134-448a-9c19-949ce1958424</code></p><p><b>title</b>: Bacterial Endotoxins</p><p><b>status</b>: active</p><p><b>code</b>: Bacterial Endotoxins (EU/mL) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Bacterial Endotoxins (EU/mL))</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>50-110 EU/mL</td></tr></table></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/64515b4c-5134-448a-9c19-949ce1958424",
            "title" : "Bacterial Endotoxins",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/64515b4c-5134-448a-9c19-949ce1958424
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Bacterial Endotoxins (EU/mL)",
                  "display" : "Bacterial Endotoxins (EU/mL)"
                }
              ]
            },
            "qualifiedValue" : [
              {
                "range" : {
                  "low" : //  todo UCUM
                  {
                    "value" : 50,
                    "unit" : "EU/mL"
                  },
                  "high" : //  todo UCUM
                  {
                    "value" : 110,
                    "unit" : "EU/mL"
                  }
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:74515b3c-5134-448a-9c19-949ce1958434",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "74515b3c-5134-448a-9c19-949ce1958434",
            "text" : // FiltrationPressure
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_74515b3c-5134-448a-9c19-949ce1958434\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"74515b3c-5134-448a-9c19-949ce1958434\"> </a><a name=\"hc74515b3c-5134-448a-9c19-949ce1958434\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;74515b3c-5134-448a-9c19-949ce1958434&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/74515b3c-5134-448a-9c19-949ce1958434</code></p><p><b>title</b>: Filtration Pressure</p><p><b>status</b>: active</p><p><b>code</b>: FiltrationPressure (psig) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#FiltrationPressure (psig))</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>100-150 psig</td></tr></table></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/74515b3c-5134-448a-9c19-949ce1958434",
            "title" : "Filtration Pressure",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/74515b3c-5134-448a-9c19-949ce1958434
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "FiltrationPressure (psig)",
                  "display" : "FiltrationPressure (psig)"
                }
              ]
            },
            "qualifiedValue" : [
              {
                "range" : {
                  "low" : //  todo UCUM
                  {
                    "value" : 100,
                    "unit" : "psig"
                  },
                  "high" : //  todo UCUM
                  {
                    "value" : 150,
                    "unit" : "psig"
                  }
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:75515b3c-5134-448a-9c19-949ce1958434",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "75515b3c-5134-448a-9c19-949ce1958434",
            "text" : // PostFiltrationFilterIntegrity
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_75515b3c-5134-448a-9c19-949ce1958434\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"75515b3c-5134-448a-9c19-949ce1958434\"> </a><a name=\"hc75515b3c-5134-448a-9c19-949ce1958434\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;75515b3c-5134-448a-9c19-949ce1958434&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/75515b3c-5134-448a-9c19-949ce1958434</code></p><p><b>title</b>: Post-filtration Filter Integrity (psig)</p><p><b>status</b>: active</p><p><b>code</b>: Post-filtration Filter Integrity (psig) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Post-filtration Filter Integrity (psig))</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>100-? psig</td></tr></table><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td></tr><tr><td style=\"display: none\">*</td><td>Test Success <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#test-success)</span></td></tr></table></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/75515b3c-5134-448a-9c19-949ce1958434",
            "title" : "Post-filtration Filter Integrity (psig)",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/75515b3c-5134-448a-9c19-949ce1958434
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Post-filtration Filter Integrity (psig)",
                  "display" : "Post-filtration Filter Integrity (psig)"
                }
              ]
            },
            "qualifiedValue" : [
              {
                "range" : {
                  "low" : //  todo UCUM
                  {
                    "value" : 100,
                    "unit" : "psig"
                  }
                }
              }
            ],
            "component" : [
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "test-success",
                      "display" : "Test Success"
                    }
                  ]
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:75515c3c-5134-448a-9c19-949ce1958434",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "75515c3c-5134-448a-9c19-949ce1958434",
            "text" : // MediaHoldTime
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_75515c3c-5134-448a-9c19-949ce1958434\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"75515c3c-5134-448a-9c19-949ce1958434\"> </a><a name=\"hc75515c3c-5134-448a-9c19-949ce1958434\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;75515c3c-5134-448a-9c19-949ce1958434&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/75515c3c-5134-448a-9c19-949ce1958434</code></p><p><b>title</b>: Media Challenge Hold Times (hours)</p><p><b>status</b>: active</p><p><b>code</b>: Media Challenge Hold Times <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Media Challenge Hold Times)</span></p></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/75515c3c-5134-448a-9c19-949ce1958434",
            "title" : "Media Challenge Hold Times (hours)",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/75515c3c-5134-448a-9c19-949ce1958434
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Media Challenge Hold Times",
                  "display" : "Media Challenge Hold Times"
                }
              ]
            }
          }
        },
        {
          "fullUrl" : "urn:uuid:64515b3c-5134-448a-9c19-949ce1958434",
          "resource" : {
            "resourceType" : "ObservationDefinition",
            "id" : "64515b3c-5134-448a-9c19-949ce1958434",
            "text" : // Polysorbate
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ObservationDefinition_64515b3c-5134-448a-9c19-949ce1958434\"> </a><p><b>Generated Narrative: ObservationDefinition</b><a name=\"64515b3c-5134-448a-9c19-949ce1958434\"> </a><a name=\"hc64515b3c-5134-448a-9c19-949ce1958434\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ObservationDefinition &quot;64515b3c-5134-448a-9c19-949ce1958434&quot; </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9c19-949ce1958434</code></p><p><b>title</b>: Polysorbate 80</p><p><b>status</b>: active</p><p><b>code</b>: Polysorbate 80 (% w/v) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Polysorbate 80 (% w/v))</span></p><h3>QualifiedValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>25-55 % w/v</td></tr></table></div>"
            },
            "url" : "http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9c19-949ce1958434",
            "title" : "Polysorbate 80",
            "status" : "active",
            "code" : // http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9c19-949ce1958434
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Polysorbate 80 (% w/v)",
                  "display" : "Polysorbate 80 (% w/v)"
                }
              ]
            },
            "qualifiedValue" : [
              {
                "range" : {
                  "low" : //  todo UCUM
                  {
                    "value" : 25,
                    "unit" : "% w/v"
                  },
                  "high" : //  todo UCUM
                  {
                    "value" : 55,
                    "unit" : "% w/v"
                  }
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51",
          "resource" : {
            "resourceType" : "Medication",
            "id" : "339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51",
            "text" : // medication-batch-information-drug-pq-ex1
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Medication_339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51\"> </a><p><b>Generated Narrative: Medication</b><a name=\"339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51\"> </a><a name=\"hc339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Medication &quot;339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51&quot; </p></div><p><b>code</b>:  <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>Batches</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td><td><b>LotNumber</b></td></tr><tr><td style=\"display: none\">*</td><td>, , , , , , , , , , , , </td><td>999909</td></tr></table><hr/><blockquote><p><b>Generated Narrative: PackagedProductDefinition #ppd1-nosubject</b><a name=\"ppd1-nosubject\"> </a><a name=\"hcppd1-nosubject\"> </a></p><p><b>containedItemQuantity</b>: 20 ml</p></blockquote></div>"
            },
            "contained" : [
              {
                "resourceType" : "PackagedProductDefinition",
                "id" : "ppd1-nosubject",
                "containedItemQuantity" : [
                  {
                    "value" : 20,
                    "unit" : "ml"
                  }
                ]
              }
            ],
            "code" : {
              "extension" : [
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-medication-definition-pq",
                  "valueReference" : {
                    "reference" : "MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"
                  }
                },
                //  todo consider change this be the MID?
                // MedicinalProductDefinition/medicinalproductdefinition-drug-product-pq-ex1
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-package-definition-pq",
                  "valueReference" : {
                    "reference" : "#ppd1-nosubject"
                  }
                }
              ]
            },
            "batch" : // totalVolume
            //  considered this as presentation (package size). Unclear how to use it, esp. for non-liquids
            {
              "extension" : [
                {
                  "url" : "http://hl7.org/fhir/StructureDefinition/medication-manufacturingBatch",
                  "extension" : [
                    {
                      "url" : "manufacturingDate",
                      "valueDateTime" : "2020-06-01"
                    },
                    {
                      "url" : "batchQuantity",
                      "valueQuantity" : {
                        "value" : 100100,
                        "unit" : "tablets"
                      }
                    },
                    {
                      "url" : "batchUtilization",
                      "valueCodeableConcept" : {
                        "coding" : [
                          {
                            "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                            "code" : "C185328",
                            "display" : "Stability Study"
                          }
                        ],
                        "text" : "PPQ / Stability"
                      }
                    },
                    {
                      "url" : "assignedManufacturer",
                      "valueReference" : {
                        "reference" : "Organization/0102bca4-46c1-a6bf-1025-cd403fee710a"
                      }
                    },
                    // Organization/manufacturer
                    {
                      "url" : "container",
                      "extension" : [
                        {
                          "url" : "closureSystemDescription",
                          "valueString" : "100 cc HDPE Bottle 2 g desiccant"
                        }
                      ]
                    }
                  ]
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-release-date-pq",
                  "valueDateTime" : "2019-09-08"
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-formulation-number-pq",
                  "valueString" : "1333224444"
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-designation-pq",
                  "valueCodeableConcept" : {
                    "coding" : [
                      {
                        "system" : "http://terminology.hl7.org/CodeSystem/batch-designation",
                        "code" : "minimum",
                        "display" : "Minimum"
                      }
                    ],
                    "text" : "Minimum"
                  }
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-number-of-vials-pq",
                  "valuePositiveInt" : 3
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-number-of-full-shelves-pq",
                  "valuePositiveInt" : 4
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-number-of-partial-shelves-pq",
                  "valuePositiveInt" : 5
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-substance-batch-pq",
                  "valueReference" : {
                    "reference" : "Substance/fc078762-81c5-5656-9744-13c7ad1e595b"
                  }
                },
                // Substance/substance-dxpq-ex1
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-packaging-date-pq",
                  "valueDateTime" : "2020-08"
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-packaging-site-pq",
                  "valueReference" : {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b07"
                  }
                },
                // Organization/packaging
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-pq",
                  "valueQuantity" : {
                    "value" : 4.81,
                    "unit" : "kg"
                  }
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-unfiltered-pq",
                  "valueQuantity" : {
                    "value" : 4.91,
                    "unit" : "kg"
                  }
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-target-fill-weight-pq",
                  "valueQuantity" : {
                    "value" : 30,
                    "unit" : "g"
                  }
                }
              ],
              "lotNumber" : "999909"
            }
          }
        },
        //  local extensions
        {
          "fullUrl" : "urn:uuid:339b69fd-4ab1-a1e9-9ea5-1973ba2f6b51",
          "resource" : {
            "resourceType" : "Medication",
            "id" : "339b69fd-4ab1-a1e9-9ea5-1973ba2f6b51",
            "text" : // medication-batch-information-drug-pq-ex1b-unlinked
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Medication_339b69fd-4ab1-a1e9-9ea5-1973ba2f6b51\"> </a><p><b>Generated Narrative: Medication</b><a name=\"339b69fd-4ab1-a1e9-9ea5-1973ba2f6b51\"> </a><a name=\"hc339b69fd-4ab1-a1e9-9ea5-1973ba2f6b51\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Medication &quot;339b69fd-4ab1-a1e9-9ea5-1973ba2f6b51&quot; </p></div><p><b>code</b>:  <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>Batches</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td><td><b>LotNumber</b></td></tr><tr><td style=\"display: none\">*</td><td>, , , , , , , , , , </td><td>999910</td></tr></table><hr/><blockquote><p><b>Generated Narrative: PackagedProductDefinition #ppd1-nosubject</b><a name=\"ppd1-nosubject\"> </a><a name=\"hcppd1-nosubject\"> </a></p><p><b>containedItemQuantity</b>: 50 ml</p></blockquote></div>"
            },
            "contained" : [
              {
                "resourceType" : "PackagedProductDefinition",
                "id" : "ppd1-nosubject",
                "containedItemQuantity" : [
                  {
                    "value" : 50,
                    "unit" : "ml"
                  }
                ]
              }
            ],
            "code" : {
              "extension" : [
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-medication-definition-pq",
                  "valueReference" : {
                    "reference" : "MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"
                  }
                },
                //  todo consider change this be the MID?
                // MedicinalProductDefinition/medicinalproductdefinition-drug-product-pq-ex1
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-package-definition-pq",
                  "valueReference" : {
                    "reference" : "#ppd1-nosubject"
                  }
                }
              ]
            },
            "batch" : {
              "extension" : [
                {
                  "url" : "http://hl7.org/fhir/StructureDefinition/medication-manufacturingBatch",
                  "extension" : [
                    {
                      "url" : "manufacturingDate",
                      "valueDateTime" : "2020-06-02"
                    },
                    {
                      "url" : "batchQuantity",
                      "valueQuantity" : {
                        "value" : 100100,
                        "unit" : "tablets"
                      }
                    },
                    {
                      "url" : "batchUtilization",
                      "valueCodeableConcept" : {
                        "coding" : [
                          {
                            "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                            "code" : "C185328",
                            "display" : "Stability Study"
                          }
                        ],
                        "text" : "PPQ / Stability"
                      }
                    },
                    {
                      "url" : "assignedManufacturer",
                      "valueReference" : {
                        "reference" : "Organization/0102bca4-46c1-a6bf-1025-cd403fee710a"
                      }
                    },
                    // Organization/manufacturer
                    {
                      "url" : "container",
                      "extension" : [
                        {
                          "url" : "closureSystemDescription",
                          "valueString" : "100 cc HDPE Bottle 2 g desiccant"
                        }
                      ]
                    }
                  ]
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-release-date-pq",
                  "valueDateTime" : "2019-09-08"
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-formulation-number-pq",
                  "valueString" : "1333224444"
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-designation-pq",
                  "valueCodeableConcept" : {
                    "coding" : [
                      {
                        "system" : "http://terminology.hl7.org/CodeSystem/batch-designation",
                        "code" : "maximum",
                        "display" : "Maximum"
                      }
                    ],
                    "text" : "Maximum"
                  }
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-number-of-vials-pq",
                  "valuePositiveInt" : 3
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-substance-batch-pq",
                  "valueReference" : {
                    "reference" : "Substance/fc078762-81c5-5656-9744-13c7ad1e595b"
                  }
                },
                // Substance/substance-dxpq-ex1
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-packaging-date-pq",
                  "valueDateTime" : "2020-08"
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-packaging-site-pq",
                  "valueReference" : {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b07"
                  }
                },
                // Organization/packaging
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-pq",
                  "valueQuantity" : {
                    "value" : 4.81,
                    "unit" : "kg"
                  }
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-unfiltered-pq",
                  "valueQuantity" : {
                    "value" : 4.91,
                    "unit" : "kg"
                  }
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-target-fill-weight-pq",
                  "valueQuantity" : {
                    "value" : 30,
                    "unit" : "g"
                  }
                }
              ],
              "lotNumber" : "999910"
            }
          }
        },
        //  local extensions
        {
          "fullUrl" : "urn:uuid:a9dfda53-734b-045f-7ae4-94a6281d53bc",
          "resource" : {
            "resourceType" : "Medication",
            "id" : "a9dfda53-734b-045f-7ae4-94a6281d53bc",
            "text" : // medication-actual-batch-2
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Medication_a9dfda53-734b-045f-7ae4-94a6281d53bc\"> </a><p><b>Generated Narrative: Medication</b><a name=\"a9dfda53-734b-045f-7ae4-94a6281d53bc\"> </a><a name=\"hca9dfda53-734b-045f-7ae4-94a6281d53bc\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Medication &quot;a9dfda53-734b-045f-7ae4-94a6281d53bc&quot; </p></div><p><b>code</b>:  <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>Batches</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td><td><b>LotNumber</b></td></tr><tr><td style=\"display: none\">*</td><td>, , , , , , , , , , </td><td>999911</td></tr></table><hr/><blockquote><p><b>Generated Narrative: PackagedProductDefinition #ppd1-nosubject</b><a name=\"ppd1-nosubject\"> </a><a name=\"hcppd1-nosubject\"> </a></p><p><b>containedItemQuantity</b>: 20 ml</p></blockquote></div>"
            },
            "contained" : [
              {
                "resourceType" : "PackagedProductDefinition",
                "id" : "ppd1-nosubject",
                "containedItemQuantity" : [
                  {
                    "value" : 20,
                    "unit" : "ml"
                  }
                ]
              }
            ],
            "code" : {
              "extension" : [
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-medication-definition-pq",
                  "valueReference" : {
                    "reference" : "MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"
                  }
                },
                // MedicinalProductDefinition/medicinalproductdefinition-drug-product-pq-ex1
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-package-definition-pq",
                  "valueReference" : {
                    "reference" : "#ppd1-nosubject"
                  }
                }
              ]
            },
            "batch" : {
              "extension" : [
                {
                  "url" : "http://hl7.org/fhir/StructureDefinition/medication-manufacturingBatch",
                  "extension" : [
                    {
                      "url" : "manufacturingDate",
                      "valueDateTime" : "2020-06-01"
                    },
                    {
                      "url" : "batchQuantity",
                      "valueQuantity" : {
                        "value" : 100050,
                        "unit" : "tablets"
                      }
                    },
                    {
                      "url" : "batchUtilization",
                      "valueCodeableConcept" : {
                        "coding" : [
                          {
                            "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                            "code" : "C185328",
                            "display" : "Stability Study"
                          }
                        ],
                        "text" : "PPQ / Stability"
                      }
                    },
                    {
                      "url" : "assignedManufacturer",
                      "valueReference" : {
                        "reference" : "Organization/0102bca4-46c1-a6bf-1025-cd403fee710a"
                      }
                    },
                    // Organization/manufacturer
                    {
                      "url" : "container",
                      "extension" : [
                        {
                          "url" : "closureSystemDescription",
                          "valueString" : "100 cc HDPE Bottle 2 g desiccant"
                        }
                      ]
                    }
                  ]
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-release-date-pq",
                  "valueDateTime" : "2019-09-08"
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-formulation-number-pq",
                  "valueString" : "1333225555"
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-designation-pq",
                  "valueCodeableConcept" : {
                    "coding" : [
                      {
                        "system" : "http://terminology.hl7.org/CodeSystem/batch-designation",
                        "code" : "maximum",
                        "display" : "Maximum"
                      }
                    ],
                    "text" : "Maximum"
                  }
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-number-of-vials-pq",
                  "valuePositiveInt" : 4
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-substance-batch-pq",
                  "valueReference" : {
                    "reference" : "Substance/cb31d747-2338-88d5-342c-8e9c097e4dad"
                  }
                },
                // Substance/actual-batch-substance-2
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-packaging-date-pq",
                  "valueDateTime" : "2020-08"
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-packaging-site-pq",
                  "valueReference" : {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b07"
                  }
                },
                // Organization/packaging
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-pq",
                  "valueQuantity" : {
                    "value" : 4.82,
                    "unit" : "kg"
                  }
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-unfiltered-pq",
                  "valueQuantity" : {
                    "value" : 4.92,
                    "unit" : "kg"
                  }
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-target-fill-weight-pq",
                  "valueQuantity" : {
                    "value" : 30,
                    "unit" : "g"
                  }
                }
              ],
              "lotNumber" : "999911"
            }
          }
        },
        //  local extensions
        {
          "fullUrl" : "urn:uuid:a9dfda53-734b-045f-7ae5-94a6281d53bc",
          "resource" : {
            "resourceType" : "Medication",
            "id" : "a9dfda53-734b-045f-7ae5-94a6281d53bc",
            "text" : // medication-actual-batch-2b-unlinked
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Medication_a9dfda53-734b-045f-7ae5-94a6281d53bc\"> </a><p><b>Generated Narrative: Medication</b><a name=\"a9dfda53-734b-045f-7ae5-94a6281d53bc\"> </a><a name=\"hca9dfda53-734b-045f-7ae5-94a6281d53bc\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Medication &quot;a9dfda53-734b-045f-7ae5-94a6281d53bc&quot; </p></div><p><b>code</b>:  <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>Batches</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td><td><b>LotNumber</b></td></tr><tr><td style=\"display: none\">*</td><td>, , , , , , , , , , </td><td>999912</td></tr></table><hr/><blockquote><p><b>Generated Narrative: PackagedProductDefinition #ppd1-nosubject</b><a name=\"ppd1-nosubject\"> </a><a name=\"hcppd1-nosubject\"> </a></p><p><b>containedItemQuantity</b>: 50 ml</p></blockquote></div>"
            },
            "contained" : [
              {
                "resourceType" : "PackagedProductDefinition",
                "id" : "ppd1-nosubject",
                "containedItemQuantity" : [
                  {
                    "value" : 50,
                    "unit" : "ml"
                  }
                ]
              }
            ],
            "code" : {
              "extension" : [
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-medication-definition-pq",
                  "valueReference" : {
                    "reference" : "MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"
                  }
                },
                // MedicinalProductDefinition/medicinalproductdefinition-drug-product-pq-ex1
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-package-definition-pq",
                  "valueReference" : {
                    "reference" : "#ppd1-nosubject"
                  }
                }
              ]
            },
            "batch" : {
              "extension" : [
                {
                  "url" : "http://hl7.org/fhir/StructureDefinition/medication-manufacturingBatch",
                  "extension" : [
                    {
                      "url" : "manufacturingDate",
                      "valueDateTime" : "2020-06-02"
                    },
                    {
                      "url" : "batchQuantity",
                      "valueQuantity" : {
                        "value" : 100050,
                        "unit" : "tablets"
                      }
                    },
                    {
                      "url" : "batchUtilization",
                      "valueCodeableConcept" : {
                        "coding" : [
                          {
                            "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                            "code" : "C185328",
                            "display" : "Stability Study"
                          }
                        ],
                        "text" : "PPQ / Stability"
                      }
                    },
                    {
                      "url" : "assignedManufacturer",
                      "valueReference" : {
                        "reference" : "Organization/0102bca4-46c1-a6bf-1025-cd403fee710a"
                      }
                    },
                    // Organization/manufacturer
                    {
                      "url" : "container",
                      "extension" : [
                        {
                          "url" : "closureSystemDescription",
                          "valueString" : "100 cc HDPE Bottle 2 g desiccant"
                        }
                      ]
                    }
                  ]
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-release-date-pq",
                  "valueDateTime" : "2019-09-08"
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-formulation-number-pq",
                  "valueString" : "1333225555"
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-designation-pq",
                  "valueCodeableConcept" : {
                    "coding" : [
                      {
                        "system" : "http://terminology.hl7.org/CodeSystem/batch-designation",
                        "code" : "maximum",
                        "display" : "Maximum"
                      }
                    ],
                    "text" : "Maximum"
                  }
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-number-of-vials-pq",
                  "valuePositiveInt" : 4
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-substance-batch-pq",
                  "valueReference" : {
                    "reference" : "Substance/cb31d747-2338-88d5-342c-8e9c097e4dad"
                  }
                },
                // Substance/actual-batch-substance-2
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-packaging-date-pq",
                  "valueDateTime" : "2020-08"
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-packaging-site-pq",
                  "valueReference" : {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b07"
                  }
                },
                // Organization/packaging
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-pq",
                  "valueQuantity" : {
                    "value" : 4.82,
                    "unit" : "kg"
                  }
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-unfiltered-pq",
                  "valueQuantity" : {
                    "value" : 4.92,
                    "unit" : "kg"
                  }
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-target-fill-weight-pq",
                  "valueQuantity" : {
                    "value" : 30,
                    "unit" : "g"
                  }
                }
              ],
              "lotNumber" : "999912"
            }
          }
        },
        //  local extensions
        {
          "fullUrl" : "urn:uuid:c6f5fadd-62e6-3a01-93d9-b3b182f67d06",
          "resource" : {
            "resourceType" : "Medication",
            "id" : "c6f5fadd-62e6-3a01-93d9-b3b182f67d06",
            "text" : // medication-actual-batch-3
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Medication_c6f5fadd-62e6-3a01-93d9-b3b182f67d06\"> </a><p><b>Generated Narrative: Medication</b><a name=\"c6f5fadd-62e6-3a01-93d9-b3b182f67d06\"> </a><a name=\"hcc6f5fadd-62e6-3a01-93d9-b3b182f67d06\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Medication &quot;c6f5fadd-62e6-3a01-93d9-b3b182f67d06&quot; </p></div><p><b>code</b>:  <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>Batches</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td><td><b>LotNumber</b></td></tr><tr><td style=\"display: none\">*</td><td>, , , , , , , , , , </td><td>999913</td></tr></table><hr/><blockquote><p><b>Generated Narrative: PackagedProductDefinition #ppd1-nosubject</b><a name=\"ppd1-nosubject\"> </a><a name=\"hcppd1-nosubject\"> </a></p><p><b>containedItemQuantity</b>: 20 ml</p></blockquote></div>"
            },
            "contained" : [
              {
                "resourceType" : "PackagedProductDefinition",
                "id" : "ppd1-nosubject",
                "containedItemQuantity" : [
                  {
                    "value" : 20,
                    "unit" : "ml"
                  }
                ]
              }
            ],
            "code" : {
              "extension" : [
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-medication-definition-pq",
                  "valueReference" : {
                    "reference" : "MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"
                  }
                },
                // MedicinalProductDefinition/medicinalproductdefinition-drug-product-pq-ex1
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-package-definition-pq",
                  "valueReference" : {
                    "reference" : "#ppd1-nosubject"
                  }
                }
              ]
            },
            "batch" : {
              "extension" : [
                {
                  "url" : "http://hl7.org/fhir/StructureDefinition/medication-manufacturingBatch",
                  "extension" : [
                    {
                      "url" : "manufacturingDate",
                      "valueDateTime" : "2020-06-01"
                    },
                    {
                      "url" : "batchQuantity",
                      "valueQuantity" : {
                        "value" : 100125,
                        "unit" : "tablets"
                      }
                    },
                    {
                      "url" : "batchUtilization",
                      "valueCodeableConcept" : {
                        "coding" : [
                          {
                            "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                            "code" : "C185328",
                            "display" : "Stability Study"
                          }
                        ],
                        "text" : "PPQ / Stability"
                      }
                    },
                    {
                      "url" : "assignedManufacturer",
                      "valueReference" : {
                        "reference" : "Organization/0102bca4-46c1-a6bf-1025-cd403fee710a"
                      }
                    },
                    // Organization/manufacturer
                    {
                      "url" : "container",
                      "extension" : [
                        {
                          "url" : "closureSystemDescription",
                          "valueString" : "100 cc HDPE Bottle 2 g desiccant"
                        }
                      ]
                    }
                  ]
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-release-date-pq",
                  "valueDateTime" : "2019-09-08"
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-formulation-number-pq",
                  "valueString" : "1333226666"
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-designation-pq",
                  "valueCodeableConcept" : {
                    "coding" : [
                      {
                        "system" : "http://terminology.hl7.org/CodeSystem/batch-designation",
                        "code" : "maximum",
                        "display" : "Maximum"
                      }
                    ],
                    "text" : "Maximum"
                  }
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-number-of-vials-pq",
                  "valuePositiveInt" : 3
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-substance-batch-pq",
                  "valueReference" : {
                    "reference" : "Substance/1551f97b-6f6d-825e-1fb3-44b0b090808c"
                  }
                },
                // Substance/actual-batch-substance-3
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-packaging-date-pq",
                  "valueDateTime" : "2020-08"
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-packaging-site-pq",
                  "valueReference" : {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b07"
                  }
                },
                // Organization/packaging
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-pq",
                  "valueQuantity" : {
                    "value" : 4.83,
                    "unit" : "kg"
                  }
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-unfiltered-pq",
                  "valueQuantity" : {
                    "value" : 4.93,
                    "unit" : "kg"
                  }
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-target-fill-weight-pq",
                  "valueQuantity" : {
                    "value" : 30,
                    "unit" : "g"
                  }
                }
              ],
              "lotNumber" : "999913"
            }
          }
        },
        //  local extension
        {
          "fullUrl" : "urn:uuid:c6f5fadd-62e6-3a11-93d9-b3b182f67d06",
          "resource" : {
            "resourceType" : "Medication",
            "id" : "c6f5fadd-62e6-3a11-93d9-b3b182f67d06",
            "text" : // medication-actual-batch-3b-unlinked
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Medication_c6f5fadd-62e6-3a11-93d9-b3b182f67d06\"> </a><p><b>Generated Narrative: Medication</b><a name=\"c6f5fadd-62e6-3a11-93d9-b3b182f67d06\"> </a><a name=\"hcc6f5fadd-62e6-3a11-93d9-b3b182f67d06\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Medication &quot;c6f5fadd-62e6-3a11-93d9-b3b182f67d06&quot; </p></div><p><b>code</b>:  <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>Batches</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td><td><b>LotNumber</b></td></tr><tr><td style=\"display: none\">*</td><td>, , , , , , , , , , </td><td>999914</td></tr></table><hr/><blockquote><p><b>Generated Narrative: PackagedProductDefinition #ppd1-nosubject</b><a name=\"ppd1-nosubject\"> </a><a name=\"hcppd1-nosubject\"> </a></p><p><b>containedItemQuantity</b>: 50 ml</p></blockquote></div>"
            },
            "contained" : [
              {
                "resourceType" : "PackagedProductDefinition",
                "id" : "ppd1-nosubject",
                "containedItemQuantity" : [
                  {
                    "value" : 50,
                    "unit" : "ml"
                  }
                ]
              }
            ],
            "code" : {
              "extension" : [
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-medication-definition-pq",
                  "valueReference" : {
                    "reference" : "MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"
                  }
                },
                // MedicinalProductDefinition/medicinalproductdefinition-drug-product-pq-ex1
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-package-definition-pq",
                  "valueReference" : {
                    "reference" : "#ppd1-nosubject"
                  }
                }
              ]
            },
            "batch" : {
              "extension" : [
                {
                  "url" : "http://hl7.org/fhir/StructureDefinition/medication-manufacturingBatch",
                  "extension" : [
                    {
                      "url" : "manufacturingDate",
                      "valueDateTime" : "2020-06-02"
                    },
                    {
                      "url" : "batchQuantity",
                      "valueQuantity" : {
                        "value" : 100125,
                        "unit" : "tablets"
                      }
                    },
                    {
                      "url" : "batchUtilization",
                      "valueCodeableConcept" : {
                        "coding" : [
                          {
                            "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                            "code" : "C185328",
                            "display" : "Stability Study"
                          }
                        ],
                        "text" : "PPQ / Stability"
                      }
                    },
                    {
                      "url" : "assignedManufacturer",
                      "valueReference" : {
                        "reference" : "Organization/0102bca4-46c1-a6bf-1025-cd403fee710a"
                      }
                    },
                    // Organization/manufacturer
                    {
                      "url" : "container",
                      "extension" : [
                        {
                          "url" : "closureSystemDescription",
                          "valueString" : "100 cc HDPE Bottle 2 g desiccant"
                        }
                      ]
                    }
                  ]
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-release-date-pq",
                  "valueDateTime" : "2019-09-08"
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-formulation-number-pq",
                  "valueString" : "1333226666"
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-designation-pq",
                  "valueCodeableConcept" : {
                    "coding" : [
                      {
                        "system" : "http://terminology.hl7.org/CodeSystem/batch-designation",
                        "code" : "intermediate",
                        "display" : "Intermediate"
                      }
                    ],
                    "text" : "Intermediate"
                  }
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-number-of-vials-pq",
                  "valuePositiveInt" : 3
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-substance-batch-pq",
                  "valueReference" : {
                    "reference" : "Substance/1551f97b-6f6d-825e-1fb3-44b0b090808c"
                  }
                },
                // Substance/actual-batch-substance-3
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-packaging-date-pq",
                  "valueDateTime" : "2020-08"
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-packaging-site-pq",
                  "valueReference" : {
                    "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b07"
                  }
                },
                // Organization/packaging
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-pq",
                  "valueQuantity" : {
                    "value" : 4.83,
                    "unit" : "kg"
                  }
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-unfiltered-pq",
                  "valueQuantity" : {
                    "value" : 4.93,
                    "unit" : "kg"
                  }
                },
                {
                  "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-target-fill-weight-pq",
                  "valueQuantity" : {
                    "value" : 30,
                    "unit" : "g"
                  }
                }
              ],
              "lotNumber" : "999914"
            }
          }
        },
        //  local extension
        {
          "fullUrl" : "urn:uuid:0102bca4-46c1-a6bf-1025-cd403fee710a",
          "resource" : {
            "resourceType" : "Organization",
            "id" : "0102bca4-46c1-a6bf-1025-cd403fee710a",
            "text" : // manufacturer
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Organization_0102bca4-46c1-a6bf-1025-cd403fee710a\"> </a><p><b>Generated Narrative: Organization</b><a name=\"0102bca4-46c1-a6bf-1025-cd403fee710a\"> </a><a name=\"hc0102bca4-46c1-a6bf-1025-cd403fee710a\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Organization &quot;0102bca4-46c1-a6bf-1025-cd403fee710a&quot; </p></div><p><b>identifier</b>: <code>urn:oid:2.16.840.1.113883.4.82</code>/3010027650</p><p><b>active</b>: true</p><p><b>type</b>: Drug Product Manufacture <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-organization-type.html\">Pharmaceutical Organization Type Codes</a>#drug-product-manufacture)</span></p><p><b>name</b>: AAA Pharmaceutical, Inc.</p><h3>Contacts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Address</b></td></tr><tr><td style=\"display: none\">*</td><td>681 Main Street Lumberton New Jersey 08048 USA </td></tr></table></div>"
            },
            "identifier" : [
              {
                "system" : "urn:oid:2.16.840.1.113883.4.82",
                "value" : "3010027650"
              }
            ],
            "active" : true,
            "type" : [
              //  FDA establishment identifier
              {
                "coding" : [
                  {
                    "system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-organization-type",
                    "code" : "drug-product-manufacture",
                    "display" : "Drug Product Manufacture"
                  }
                ]
              }
            ],
            "name" : "AAA Pharmaceutical, Inc.",
            "contact" : [
              {
                "address" : {
                  "line" : [
                    "681 Main Street"
                  ],
                  "city" : "Lumberton",
                  "state" : "New Jersey",
                  "postalCode" : "08048",
                  "country" : "USA"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:378fbe5f-5926-3a5c-4c64-5428df877b07",
          "resource" : {
            "resourceType" : "Organization",
            "id" : "378fbe5f-5926-3a5c-4c64-5428df877b07",
            "text" : // packaging
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Organization_378fbe5f-5926-3a5c-4c64-5428df877b07\"> </a><p><b>Generated Narrative: Organization</b><a name=\"378fbe5f-5926-3a5c-4c64-5428df877b07\"> </a><a name=\"hc378fbe5f-5926-3a5c-4c64-5428df877b07\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Organization &quot;378fbe5f-5926-3a5c-4c64-5428df877b07&quot; </p></div><p><b>identifier</b>: <code>urn:oid:2.16.840.1.113883.4.82</code>/3008816891</p><p><b>active</b>: true</p><p><b>type</b>: Packaging <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-organization-type.html\">Pharmaceutical Organization Type Codes</a>#packaging)</span></p><p><b>name</b>: MySite</p></div>"
            },
            "identifier" : [
              {
                "system" : "urn:oid:2.16.840.1.113883.4.82",
                "value" : "3008816891"
              }
            ],
            "active" : true,
            "type" : [
              {
                "coding" : [
                  {
                    "system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-organization-type",
                    "code" : "packaging",
                    "display" : "Packaging"
                  }
                ]
              }
            ],
            "name" : "MySite"
          }
        },
        {
          "fullUrl" : "urn:uuid:9c56948a-2a39-6609-1c01-4d197ea57a33",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "9c56948a-2a39-6609-1c01-4d197ea57a33",
            "text" : // bufferVesselMixingSpeed1
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_9c56948a-2a39-6609-1c01-4d197ea57a33\"> </a><p><b>Generated Narrative: Observation</b><a name=\"9c56948a-2a39-6609-1c01-4d197ea57a33\"> </a><a name=\"hc9c56948a-2a39-6609-1c01-4d197ea57a33\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;9c56948a-2a39-6609-1c01-4d197ea57a33&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/fd17b5d6-9fe1-91c2-2d06-47cb5b295e72</p><p><b>status</b>: final</p><p><b>code</b>: Buffer vessel mixing speed (rpm) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Buffer vessel mixing speed (rpm))</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 205 rpm</p></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/fd17b5d6-9fe1-91c2-2d06-47cb5b295e72"
            },
            "status" : "final",
            "code" : // ObservationDefinition/bufferVesselMixingSpeed
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Buffer vessel mixing speed (rpm)",
                  "display" : "Buffer vessel mixing speed (rpm)"
                }
              ],
              "text" : "Buffer vessel mixing speed (rpm)"
            },
            "subject" : {
              "reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Medication/medication-batch-information-drug-pq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 205,
              "unit" : "rpm"
            }
          }
        },
        {
          "fullUrl" : "urn:uuid:9c56948a-3a39-6609-1c01-4d197ea57a33",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "9c56948a-3a39-6609-1c01-4d197ea57a33",
            "text" : // bufferVesselMixingSpeed2
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_9c56948a-3a39-6609-1c01-4d197ea57a33\"> </a><p><b>Generated Narrative: Observation</b><a name=\"9c56948a-3a39-6609-1c01-4d197ea57a33\"> </a><a name=\"hc9c56948a-3a39-6609-1c01-4d197ea57a33\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;9c56948a-3a39-6609-1c01-4d197ea57a33&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/fd17b5d6-9fe1-91c2-2d06-47cb5b295e72</p><p><b>status</b>: final</p><p><b>code</b>: Buffer vessel mixing speed (rpm) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Buffer vessel mixing speed (rpm))</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 210 rpm</p></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/fd17b5d6-9fe1-91c2-2d06-47cb5b295e72"
            },
            "status" : "final",
            "code" : // ObservationDefinition/bufferVesselMixingSpeed
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Buffer vessel mixing speed (rpm)",
                  "display" : "Buffer vessel mixing speed (rpm)"
                }
              ],
              "text" : "Buffer vessel mixing speed (rpm)"
            },
            "subject" : {
              "reference" : "Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Medication/medication-actual-batch-2
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 210,
              "unit" : "rpm"
            }
          }
        },
        {
          "fullUrl" : "urn:uuid:9c56948a-4a39-6609-1c01-4d197ea57a33",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "9c56948a-4a39-6609-1c01-4d197ea57a33",
            "text" : // bufferVesselMixingSpeed3
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_9c56948a-4a39-6609-1c01-4d197ea57a33\"> </a><p><b>Generated Narrative: Observation</b><a name=\"9c56948a-4a39-6609-1c01-4d197ea57a33\"> </a><a name=\"hc9c56948a-4a39-6609-1c01-4d197ea57a33\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;9c56948a-4a39-6609-1c01-4d197ea57a33&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/fd17b5d6-9fe1-91c2-2d06-47cb5b295e72</p><p><b>status</b>: final</p><p><b>code</b>: Buffer vessel mixing speed (rpm) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Buffer vessel mixing speed (rpm))</span></p><p><b>subject</b>: See on this page: Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 198 rpm</p></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/fd17b5d6-9fe1-91c2-2d06-47cb5b295e72"
            },
            "status" : "final",
            "code" : // ObservationDefinition/bufferVesselMixingSpeed
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Buffer vessel mixing speed (rpm)",
                  "display" : "Buffer vessel mixing speed (rpm)"
                }
              ],
              "text" : "Buffer vessel mixing speed (rpm)"
            },
            "subject" : {
              "reference" : "Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Medication/medication-actual-batch-3
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 198,
              "unit" : "rpm"
            }
          }
        },
        {
          "fullUrl" : "urn:uuid:9c56948a-2a39-6609-2c01-4d197ea57a33",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "9c56948a-2a39-6609-2c01-4d197ea57a33",
            "text" : // bufferVesselMixingTime1
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_9c56948a-2a39-6609-2c01-4d197ea57a33\"> </a><p><b>Generated Narrative: Observation</b><a name=\"9c56948a-2a39-6609-2c01-4d197ea57a33\"> </a><a name=\"hc9c56948a-2a39-6609-2c01-4d197ea57a33\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;9c56948a-2a39-6609-2c01-4d197ea57a33&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e73</p><p><b>status</b>: final</p><p><b>code</b>: Buffer vessel mixing time (min) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Buffer vessel mixing time (min))</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 51 mins</p></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e73"
            },
            "status" : "final",
            "code" : // ObservationDefinition/bufferVesselMixingTime
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Buffer vessel mixing time (min)",
                  "display" : "Buffer vessel mixing time (min)"
                }
              ],
              "text" : "Buffer vessel mixing time (min)"
            },
            "subject" : {
              "reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Medication/medication-batch-information-drug-pq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 51,
              "unit" : "mins"
            }
          }
        },
        {
          "fullUrl" : "urn:uuid:9c56948a-3a39-6609-2c01-4d197ea57a33",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "9c56948a-3a39-6609-2c01-4d197ea57a33",
            "text" : // bufferVesselMixingTime2
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_9c56948a-3a39-6609-2c01-4d197ea57a33\"> </a><p><b>Generated Narrative: Observation</b><a name=\"9c56948a-3a39-6609-2c01-4d197ea57a33\"> </a><a name=\"hc9c56948a-3a39-6609-2c01-4d197ea57a33\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;9c56948a-3a39-6609-2c01-4d197ea57a33&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e73</p><p><b>status</b>: final</p><p><b>code</b>: Buffer vessel mixing time (min) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Buffer vessel mixing time (min))</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 49 mins</p></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e73"
            },
            "status" : "final",
            "code" : // ObservationDefinition/bufferVesselMixingTime
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Buffer vessel mixing time (min)",
                  "display" : "Buffer vessel mixing time (min)"
                }
              ],
              "text" : "Buffer vessel mixing time (min)"
            },
            "subject" : {
              "reference" : "Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Medication/medication-actual-batch-2
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 49,
              "unit" : "mins"
            }
          }
        },
        {
          "fullUrl" : "urn:uuid:9c56948a-4a39-6609-3c01-4d197ea57a33",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "9c56948a-4a39-6609-3c01-4d197ea57a33",
            "text" : // bufferVesselMixingTime3
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_9c56948a-4a39-6609-3c01-4d197ea57a33\"> </a><p><b>Generated Narrative: Observation</b><a name=\"9c56948a-4a39-6609-3c01-4d197ea57a33\"> </a><a name=\"hc9c56948a-4a39-6609-3c01-4d197ea57a33\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;9c56948a-4a39-6609-3c01-4d197ea57a33&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e73</p><p><b>status</b>: final</p><p><b>code</b>: Buffer vessel mixing time (min) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Buffer vessel mixing time (min))</span></p><p><b>subject</b>: See on this page: Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 52 mins</p></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e73"
            },
            "status" : "final",
            "code" : // ObservationDefinition/bufferVesselMixingTime
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Buffer vessel mixing time (min)",
                  "display" : "Buffer vessel mixing time (min)"
                }
              ],
              "text" : "Buffer vessel mixing time (min)"
            },
            "subject" : {
              "reference" : "Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Medication/medication-actual-batch-3
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 52,
              "unit" : "mins"
            }
          }
        },
        {
          "fullUrl" : "urn:uuid:44aa47fd-8964-4f96-6495-b2bec7f160e7",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "44aa47fd-8964-4f96-6495-b2bec7f160e7",
            "text" : // ph1
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_44aa47fd-8964-4f96-6495-b2bec7f160e7\"> </a><p><b>Generated Narrative: Observation</b><a name=\"44aa47fd-8964-4f96-6495-b2bec7f160e7\"> </a><a name=\"hc44aa47fd-8964-4f96-6495-b2bec7f160e7\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;44aa47fd-8964-4f96-6495-b2bec7f160e7&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/fc17b5d6-9fe1-91c2-2d16-47cb5b295e72</p><p><b>status</b>: final</p><p><b>code</b>: pH <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#pH)</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 6.9 pH</p></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/fc17b5d6-9fe1-91c2-2d16-47cb5b295e72"
            },
            "status" : "final",
            "code" : // ObservationDefinition/FBPPIpH
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "pH",
                  "display" : "pH"
                }
              ],
              "text" : "pH"
            },
            "subject" : {
              "reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Medication/medication-batch-information-drug-pq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 6.9,
              "unit" : "pH"
            }
          }
        },
        {
          "fullUrl" : "urn:uuid:54aa47fd-8964-4f96-6495-b2bec7f160e7",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "54aa47fd-8964-4f96-6495-b2bec7f160e7",
            "text" : // ph2
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_54aa47fd-8964-4f96-6495-b2bec7f160e7\"> </a><p><b>Generated Narrative: Observation</b><a name=\"54aa47fd-8964-4f96-6495-b2bec7f160e7\"> </a><a name=\"hc54aa47fd-8964-4f96-6495-b2bec7f160e7\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;54aa47fd-8964-4f96-6495-b2bec7f160e7&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/fc17b5d6-9fe1-91c2-2d16-47cb5b295e72</p><p><b>status</b>: final</p><p><b>code</b>: pH <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#pH)</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 7.1 pH</p></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/fc17b5d6-9fe1-91c2-2d16-47cb5b295e72"
            },
            "status" : "final",
            "code" : // ObservationDefinition/FBPPIpH
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "pH",
                  "display" : "pH"
                }
              ],
              "text" : "pH"
            },
            "subject" : {
              "reference" : "Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Medication/medication-actual-batch-2
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 7.1,
              "unit" : "pH"
            }
          }
        },
        {
          "fullUrl" : "urn:uuid:54aa48fd-8964-4f96-6495-b2bec7f160e7",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "54aa48fd-8964-4f96-6495-b2bec7f160e7",
            "text" : // ph3
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_54aa48fd-8964-4f96-6495-b2bec7f160e7\"> </a><p><b>Generated Narrative: Observation</b><a name=\"54aa48fd-8964-4f96-6495-b2bec7f160e7\"> </a><a name=\"hc54aa48fd-8964-4f96-6495-b2bec7f160e7\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;54aa48fd-8964-4f96-6495-b2bec7f160e7&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/fc17b5d6-9fe1-91c2-2d16-47cb5b295e72</p><p><b>status</b>: final</p><p><b>code</b>: pH <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#pH)</span></p><p><b>subject</b>: See on this page: Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 7.2 pH</p></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/fc17b5d6-9fe1-91c2-2d16-47cb5b295e72"
            },
            "status" : "final",
            "code" : // ObservationDefinition/FBPPIpH
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "pH",
                  "display" : "pH"
                }
              ],
              "text" : "pH"
            },
            "subject" : {
              "reference" : "Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Medication/medication-actual-batch-3
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 7.2,
              "unit" : "pH"
            }
          }
        },
        {
          "fullUrl" : "urn:uuid:44aa47fd-9964-5f96-6495-b2bec7f161e8",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "44aa47fd-9964-5f96-6495-b2bec7f161e8",
            "text" : // mediaChallengeHoldTimesStep1
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_44aa47fd-9964-5f96-6495-b2bec7f161e8\"> </a><p><b>Generated Narrative: Observation</b><a name=\"44aa47fd-9964-5f96-6495-b2bec7f161e8\"> </a><a name=\"hc44aa47fd-9964-5f96-6495-b2bec7f161e8\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;44aa47fd-9964-5f96-6495-b2bec7f161e8&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/75515c3c-5134-448a-9c19-949ce1958434</p><p><b>status</b>: final</p><p><b>code</b>: Hold Time (hr) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Hold Time &quot;Hold Time&quot;)</span></p><p><b>subject</b>: See on this page: Procedure/44aa47fd-8964-5f96-8495-b2bec7f161a8</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 1.25 hours</p></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/75515c3c-5134-448a-9c19-949ce1958434"
            },
            "status" : "final",
            "code" : // ObservationDefinition/MediaHoldTime
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Hold Time",
                  "display" : "Hold Time"
                }
              ],
              "text" : "Hold Time (hr)"
            },
            "subject" : {
              "reference" : "Procedure/44aa47fd-8964-5f96-8495-b2bec7f161a8"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Procedure/procedure-drug-pq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 1.25,
              "unit" : "hours"
            }
          }
        },
        {
          "fullUrl" : "urn:uuid:44aa47fd-8964-5f96-6495-b2bec7f161e8",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "44aa47fd-8964-5f96-6495-b2bec7f161e8",
            "text" : // mediaChallengeHoldTimesStep2
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_44aa47fd-8964-5f96-6495-b2bec7f161e8\"> </a><p><b>Generated Narrative: Observation</b><a name=\"44aa47fd-8964-5f96-6495-b2bec7f161e8\"> </a><a name=\"hc44aa47fd-8964-5f96-6495-b2bec7f161e8\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;44aa47fd-8964-5f96-6495-b2bec7f161e8&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/75515c3c-5134-448a-9c19-949ce1958434</p><p><b>status</b>: final</p><p><b>code</b>: Hold Time (hr) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Hold Time &quot;Hold Time&quot;)</span></p><p><b>subject</b>: See on this page: Procedure/44aa47fd-8964-5f96-6495-b2bec7f162a8</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 1.5 hours</p></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/75515c3c-5134-448a-9c19-949ce1958434"
            },
            "status" : "final",
            "code" : // ObservationDefinition/MediaHoldTime
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Hold Time",
                  "display" : "Hold Time"
                }
              ],
              "text" : "Hold Time (hr)"
            },
            "subject" : {
              "reference" : "Procedure/44aa47fd-8964-5f96-6495-b2bec7f162a8"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Procedure/procedure-run-2
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 1.5,
              "unit" : "hours"
            }
          }
        },
        {
          "fullUrl" : "urn:uuid:44aa47fd-8964-5f96-7495-b2bec7f161e8",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "44aa47fd-8964-5f96-7495-b2bec7f161e8",
            "text" : // mediaChallengeHoldTimesStep3
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_44aa47fd-8964-5f96-7495-b2bec7f161e8\"> </a><p><b>Generated Narrative: Observation</b><a name=\"44aa47fd-8964-5f96-7495-b2bec7f161e8\"> </a><a name=\"hc44aa47fd-8964-5f96-7495-b2bec7f161e8\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;44aa47fd-8964-5f96-7495-b2bec7f161e8&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/75515c3c-5134-448a-9c19-949ce1958434</p><p><b>status</b>: final</p><p><b>code</b>: Hold Time (hr) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Hold Time &quot;Hold Time&quot;)</span></p><p><b>subject</b>: See on this page: Procedure/44aa47fd-8964-5f96-6495-b2bec7f163a8</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 1.75 hours</p></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/75515c3c-5134-448a-9c19-949ce1958434"
            },
            "status" : "final",
            "code" : // ObservationDefinition/MediaHoldTime
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Hold Time",
                  "display" : "Hold Time"
                }
              ],
              "text" : "Hold Time (hr)"
            },
            "subject" : {
              "reference" : "Procedure/44aa47fd-8964-5f96-6495-b2bec7f163a8"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Procedure/procedure-run-3
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 1.75,
              "unit" : "hours"
            }
          }
        },
        {
          "fullUrl" : "urn:uuid:44aa47fd-9964-5f97-6495-b2bec7f161e8",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "44aa47fd-9964-5f97-6495-b2bec7f161e8",
            "text" : // mediaChallengeBioburden1
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_44aa47fd-9964-5f97-6495-b2bec7f161e8\"> </a><p><b>Generated Narrative: Observation</b><a name=\"44aa47fd-9964-5f97-6495-b2bec7f161e8\"> </a><a name=\"hc44aa47fd-9964-5f97-6495-b2bec7f161e8\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;44aa47fd-9964-5f97-6495-b2bec7f161e8&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/64515b3c-5134-448a-9c19-939ce1958524</p><p><b>status</b>: final</p><p><b>code</b>: Bioburden (CFU/ 100 mL) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Bioburden (CFU/ 100 mL))</span></p><p><b>subject</b>: See on this page: Procedure/44aa47fd-8964-5f96-8495-b2bec7f161a8</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><blockquote><p><b>component</b></p><p><b>code</b>: Bioburden - Beginning <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Bioburden - Beginning)</span></p><p><b>value</b>: 8.0 CFU/100 mL</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Bioburden - End <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Bioburden - End)</span></p><p><b>value</b>: 9.0 CFU/100 mL</p></blockquote></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/64515b3c-5134-448a-9c19-939ce1958524"
            },
            "status" : "final",
            "code" : // ObservationDefinition/MediaBioburden
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Bioburden (CFU/ 100 mL)",
                  "display" : "Bioburden (CFU/ 100 mL)"
                }
              ]
            },
            "subject" : {
              "reference" : "Procedure/44aa47fd-8964-5f96-8495-b2bec7f161a8"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Procedure/procedure-drug-pq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "component" : [
              // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Bioburden - Beginning",
                      "display" : "Bioburden - Beginning"
                    }
                  ]
                },
                "valueQuantity" : //  todo UCUM
                {
                  "value" : 8.0,
                  "unit" : "CFU/100 mL"
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Bioburden - End",
                      "display" : "Bioburden - End"
                    }
                  ]
                },
                "valueQuantity" : //  todo UCUM
                {
                  "value" : 9.0,
                  "unit" : "CFU/100 mL"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:44aa47fd-8964-5f98-6495-b2bec7f161e8",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "44aa47fd-8964-5f98-6495-b2bec7f161e8",
            "text" : // mediaChallengeBioburden2
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_44aa47fd-8964-5f98-6495-b2bec7f161e8\"> </a><p><b>Generated Narrative: Observation</b><a name=\"44aa47fd-8964-5f98-6495-b2bec7f161e8\"> </a><a name=\"hc44aa47fd-8964-5f98-6495-b2bec7f161e8\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;44aa47fd-8964-5f98-6495-b2bec7f161e8&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/64515b3c-5134-448a-9c19-939ce1958524</p><p><b>status</b>: final</p><p><b>code</b>: Bioburden (CFU/ 100 mL) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Bioburden (CFU/ 100 mL))</span></p><p><b>subject</b>: See on this page: Procedure/44aa47fd-8964-5f96-6495-b2bec7f162a8</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><blockquote><p><b>component</b></p><p><b>code</b>: Bioburden - Beginning <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Bioburden - Beginning)</span></p><p><b>value</b>: 8.5 CFU/100 mL</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Bioburden - End <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Bioburden - End)</span></p><p><b>value</b>: 8.6 CFU/100 mL</p></blockquote></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/64515b3c-5134-448a-9c19-939ce1958524"
            },
            "status" : "final",
            "code" : // ObservationDefinition/MediaBioburden
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Bioburden (CFU/ 100 mL)",
                  "display" : "Bioburden (CFU/ 100 mL)"
                }
              ]
            },
            "subject" : {
              "reference" : "Procedure/44aa47fd-8964-5f96-6495-b2bec7f162a8"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Procedure/procedure-run-2
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "component" : [
              // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Bioburden - Beginning",
                      "display" : "Bioburden - Beginning"
                    }
                  ]
                },
                "valueQuantity" : //  todo UCUM
                {
                  "value" : 8.5,
                  "unit" : "CFU/100 mL"
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Bioburden - End",
                      "display" : "Bioburden - End"
                    }
                  ]
                },
                "valueQuantity" : //  todo UCUM
                {
                  "value" : 8.6,
                  "unit" : "CFU/100 mL"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:44aa47fd-8964-5f99-7495-b2bec7f161e8",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "44aa47fd-8964-5f99-7495-b2bec7f161e8",
            "text" : // mediaChallengeBioburden3
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_44aa47fd-8964-5f99-7495-b2bec7f161e8\"> </a><p><b>Generated Narrative: Observation</b><a name=\"44aa47fd-8964-5f99-7495-b2bec7f161e8\"> </a><a name=\"hc44aa47fd-8964-5f99-7495-b2bec7f161e8\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;44aa47fd-8964-5f99-7495-b2bec7f161e8&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/64515b3c-5134-448a-9c19-939ce1958524</p><p><b>status</b>: final</p><p><b>code</b>: Bioburden (CFU/ 100 mL) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Bioburden (CFU/ 100 mL))</span></p><p><b>subject</b>: See on this page: Procedure/44aa47fd-8964-5f96-6495-b2bec7f163a8</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><blockquote><p><b>component</b></p><p><b>code</b>: Bioburden - Beginning <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Bioburden - Beginning)</span></p><p><b>value</b>: 9.5 CFU/100 mL</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Bioburden - End <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Bioburden - End)</span></p><p><b>value</b>: 10.1 CFU/100 mL</p></blockquote></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/64515b3c-5134-448a-9c19-939ce1958524"
            },
            "status" : "final",
            "code" : // ObservationDefinition/MediaBioburden
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Bioburden (CFU/ 100 mL)",
                  "display" : "Bioburden (CFU/ 100 mL)"
                }
              ]
            },
            "subject" : {
              "reference" : "Procedure/44aa47fd-8964-5f96-6495-b2bec7f163a8"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Procedure/procedure-run-3
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "component" : [
              // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Bioburden - Beginning",
                      "display" : "Bioburden - Beginning"
                    }
                  ]
                },
                "valueQuantity" : //  todo UCUM
                {
                  "value" : 9.5,
                  "unit" : "CFU/100 mL"
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Bioburden - End",
                      "display" : "Bioburden - End"
                    }
                  ]
                },
                "valueQuantity" : //  todproteinConcentration1o UCUM
                {
                  "value" : 10.1,
                  "unit" : "CFU/100 mL"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:54aa47fd-9965-5f97-6495-b2bec8f161e8",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "54aa47fd-9965-5f97-6495-b2bec8f161e8",
            "text" : // proteinConcentrationStats1
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_54aa47fd-9965-5f97-6495-b2bec8f161e8\"> </a><p><b>Generated Narrative: Observation</b><a name=\"54aa47fd-9965-5f97-6495-b2bec8f161e8\"> </a><a name=\"hc54aa47fd-9965-5f97-6495-b2bec8f161e8\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;54aa47fd-9965-5f97-6495-b2bec8f161e8&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/74515b3c-5134-448a-9c19-939ce1958534</p><p><b>status</b>: final</p><p><b>code</b>: Protein Concentration (mg/mL) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Protein Concentration (mg/mL))</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Beginning - Middle - Mean <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Protein Concentration - Beginning - Middle - Mean)</span></p><p><b>value</b>: 8.0 mg/mL</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Beginning - End - Mean <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Protein Concentration - Beginning - End - Mean)</span></p><p><b>value</b>: 8.05 mg/mL</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Middle - End - Mean <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Protein Concentration - Middle - End - Mean)</span></p><p><b>value</b>: 8.10 mg/mL</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Beginning - Middle - Lower <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Protein Concentration - Beginning - Middle - Lower)</span></p><p><b>value</b>: 8.15 mg/mL</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Beginning - End - Lower <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Protein Concentration - Beginning - End - Lower)</span></p><p><b>value</b>: 8.2 mg/mL</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Middle - End - Lower <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Protein Concentration - Middle - End - Lower)</span></p><p><b>value</b>: 8.25 mg/mL</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Beginning - Middle - Higher <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Protein Concentration - Beginning - Middle - Higher)</span></p><p><b>value</b>: 8.45 mg/mL</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Beginning - End - Higher <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Protein Concentration - Beginning - End - Higher)</span></p><p><b>value</b>: 8.3 mg/mL</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Middle - End - Higher <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Protein Concentration - Middle - End - Higher)</span></p><p><b>value</b>: 8.35 mg/mL</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Conclusion <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Protein Concentration - Conclusion)</span></p><p><b>value</b>: Pass</p></blockquote></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/74515b3c-5134-448a-9c19-939ce1958534"
            },
            "status" : "final",
            "code" : // ObservationDefinition/ProteinConcentrationStats
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Protein Concentration (mg/mL)",
                  "display" : "Protein Concentration (mg/mL)"
                }
              ]
            },
            "subject" : {
              "reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Medication/medication-batch-information-drug-pq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "component" : [
              // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Protein Concentration - Beginning - Middle - Mean",
                      "display" : "Protein Concentration - Beginning - Middle - Mean"
                    }
                  ]
                },
                "valueQuantity" : //  todo UCUM
                {
                  "value" : 8.0,
                  "unit" : "mg/mL"
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Protein Concentration - Beginning - End - Mean",
                      "display" : "Protein Concentration - Beginning - End - Mean"
                    }
                  ]
                },
                "valueQuantity" : //  todo UCUM
                {
                  "value" : 8.05,
                  "unit" : "mg/mL"
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Protein Concentration - Middle - End - Mean",
                      "display" : "Protein Concentration - Middle - End - Mean"
                    }
                  ]
                },
                "valueQuantity" : //  todo UCUM
                {
                  "value" : 8.10,
                  "unit" : "mg/mL"
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Protein Concentration - Beginning - Middle - Lower",
                      "display" : "Protein Concentration - Beginning - Middle - Lower"
                    }
                  ]
                },
                "valueQuantity" : //  todo UCUM
                {
                  "value" : 8.15,
                  "unit" : "mg/mL"
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Protein Concentration - Beginning - End - Lower",
                      "display" : "Protein Concentration - Beginning - End - Lower"
                    }
                  ]
                },
                "valueQuantity" : //  todo UCUM
                {
                  "value" : 8.2,
                  "unit" : "mg/mL"
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Protein Concentration - Middle - End - Lower",
                      "display" : "Protein Concentration - Middle - End - Lower"
                    }
                  ]
                },
                "valueQuantity" : //  todo UCUM
                {
                  "value" : 8.25,
                  "unit" : "mg/mL"
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Protein Concentration - Beginning - Middle - Higher",
                      "display" : "Protein Concentration - Beginning - Middle - Higher"
                    }
                  ]
                },
                "valueQuantity" : //  todo UCUM
                {
                  "value" : 8.45,
                  "unit" : "mg/mL"
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Protein Concentration - Beginning - End - Higher",
                      "display" : "Protein Concentration - Beginning - End - Higher"
                    }
                  ]
                },
                "valueQuantity" : //  todo UCUM
                {
                  "value" : 8.3,
                  "unit" : "mg/mL"
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Protein Concentration - Middle - End - Higher",
                      "display" : "Protein Concentration - Middle - End - Higher"
                    }
                  ]
                },
                "valueQuantity" : //  todo UCUM
                {
                  "value" : 8.35,
                  "unit" : "mg/mL"
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Protein Concentration - Conclusion",
                      "display" : "Protein Concentration - Conclusion"
                    }
                  ]
                },
                "valueString" : "Pass"
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:54aa47fd-9964-5f97-6495-b2bec8f161e8",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "54aa47fd-9964-5f97-6495-b2bec8f161e8",
            "text" : // proteinConcentration1
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_54aa47fd-9964-5f97-6495-b2bec8f161e8\"> </a><p><b>Generated Narrative: Observation</b><a name=\"54aa47fd-9964-5f97-6495-b2bec8f161e8\"> </a><a name=\"hc54aa47fd-9964-5f97-6495-b2bec8f161e8\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;54aa47fd-9964-5f97-6495-b2bec8f161e8&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/74515b3c-5134-448a-9c19-939ce1958524</p><p><b>status</b>: final</p><p><b>code</b>: Protein Concentration (mg/mL) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Protein Concentration (mg/mL))</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Beginning - Min <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Protein Concentration - Beginning - Min)</span></p><p><b>value</b>: 8.00 mg/mL</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Beginning - Max <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Protein Concentration - Beginning - Max)</span></p><p><b>value</b>: 8.05 mg/mL</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Middle - Min <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Protein Concentration - Middle - Min)</span></p><p><b>value</b>: 8.10 mg/mL</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Middle - Max <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Protein Concentration - Middle - Max)</span></p><p><b>value</b>: 8.15 mg/mL</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - End - Min <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Protein Concentration - End - Min)</span></p><p><b>value</b>: 8.2 mg/mL</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - End - Max <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Protein Concentration - End - Max)</span></p><p><b>value</b>: 8.25 mg/mL</p></blockquote></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/74515b3c-5134-448a-9c19-939ce1958524"
            },
            "status" : "final",
            "code" : // ObservationDefinition/ProteinConcentration
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Protein Concentration (mg/mL)",
                  "display" : "Protein Concentration (mg/mL)"
                }
              ]
            },
            "subject" : {
              "reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Medication/medication-batch-information-drug-pq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "component" : [
              // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Protein Concentration - Beginning - Min",
                      "display" : "Protein Concentration - Beginning - Min"
                    }
                  ]
                },
                "valueQuantity" : //  todo UCUM
                {
                  "value" : 8.00,
                  "unit" : "mg/mL"
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Protein Concentration - Beginning - Max",
                      "display" : "Protein Concentration - Beginning - Max"
                    }
                  ]
                },
                "valueQuantity" : //  todo UCUM
                {
                  "value" : 8.05,
                  "unit" : "mg/mL"
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Protein Concentration - Middle - Min",
                      "display" : "Protein Concentration - Middle - Min"
                    }
                  ]
                },
                "valueQuantity" : //  todo UCUM
                {
                  "value" : 8.10,
                  "unit" : "mg/mL"
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Protein Concentration - Middle - Max",
                      "display" : "Protein Concentration - Middle - Max"
                    }
                  ]
                },
                "valueQuantity" : //  todo UCUM
                {
                  "value" : 8.15,
                  "unit" : "mg/mL"
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Protein Concentration - End - Min",
                      "display" : "Protein Concentration - End - Min"
                    }
                  ]
                },
                "valueQuantity" : //  todo UCUM
                {
                  "value" : 8.2,
                  "unit" : "mg/mL"
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Protein Concentration - End - Max",
                      "display" : "Protein Concentration - End - Max"
                    }
                  ]
                },
                "valueQuantity" : //  todo UCUM
                {
                  "value" : 8.25,
                  "unit" : "mg/mL"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:54aa47fd-9964-5f97-6495-b2bec8f162e8",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "54aa47fd-9964-5f97-6495-b2bec8f162e8",
            "text" : // polysorbate2
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_54aa47fd-9964-5f97-6495-b2bec8f162e8\"> </a><p><b>Generated Narrative: Observation</b><a name=\"54aa47fd-9964-5f97-6495-b2bec8f162e8\"> </a><a name=\"hc54aa47fd-9964-5f97-6495-b2bec8f162e8\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;54aa47fd-9964-5f97-6495-b2bec8f162e8&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/74515b3c-5234-448a-9c19-939ce1958524</p><p><b>status</b>: final</p><p><b>code</b>: Polysorbate 80 concentration (% w/v) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Polysorbate 80 concentration (% w/v))</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><blockquote><p><b>component</b></p><p><b>code</b>: Polysorbate 80 concentration - Beginning - Min <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Polysorbate 80 concentration - Beginning - Min)</span></p><p><b>value</b>: 1.0 % w/v</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Polysorbate 80 concentration - Beginning - Max <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Polysorbate 80 concentration - Beginning - Max)</span></p><p><b>value</b>: 1.05 % w/v</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Polysorbate 80 concentration - Middle - Min <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Polysorbate 80 concentration - Middle - Min)</span></p><p><b>value</b>: 1.10 % w/v</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Polysorbate 80 concentration - Middle - Max <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Polysorbate 80 concentration - Middle - Max)</span></p><p><b>value</b>: 1.15 % w/v</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Polysorbate 80 concentration - End - Min <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Polysorbate 80 concentration - End - Min)</span></p><p><b>value</b>: 1.2 % w/v</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Polysorbate 80 concentration - End - Max <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Polysorbate 80 concentration - End - Max)</span></p><p><b>value</b>: 1.25 % w/v</p></blockquote></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/74515b3c-5234-448a-9c19-939ce1958524"
            },
            "status" : "final",
            "code" : // ObservationDefinition/Polysorbate80Concentration
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Polysorbate 80 concentration (% w/v)",
                  "display" : "Polysorbate 80 concentration (% w/v)"
                }
              ]
            },
            "subject" : {
              "reference" : "Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Medication/medication-actual-batch-2
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "component" : [
              // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Polysorbate 80 concentration - Beginning - Min",
                      "display" : "Polysorbate 80 concentration - Beginning - Min"
                    }
                  ]
                },
                "valueQuantity" : //  todo UCUM
                {
                  "value" : 1.0,
                  "unit" : "% w/v"
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Polysorbate 80 concentration - Beginning - Max",
                      "display" : "Polysorbate 80 concentration - Beginning - Max"
                    }
                  ]
                },
                "valueQuantity" : //  todo UCUM
                {
                  "value" : 1.05,
                  "unit" : "% w/v"
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Polysorbate 80 concentration - Middle - Min",
                      "display" : "Polysorbate 80 concentration - Middle - Min"
                    }
                  ]
                },
                "valueQuantity" : //  todo UCUM
                {
                  "value" : 1.10,
                  "unit" : "% w/v"
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Polysorbate 80 concentration - Middle - Max",
                      "display" : "Polysorbate 80 concentration - Middle - Max"
                    }
                  ]
                },
                "valueQuantity" : //  todo UCUM
                {
                  "value" : 1.15,
                  "unit" : "% w/v"
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Polysorbate 80 concentration - End - Min",
                      "display" : "Polysorbate 80 concentration - End - Min"
                    }
                  ]
                },
                "valueQuantity" : //  todo UCUM
                {
                  "value" : 1.2,
                  "unit" : "% w/v"
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Polysorbate 80 concentration - End - Max",
                      "display" : "Polysorbate 80 concentration - End - Max"
                    }
                  ]
                },
                "valueQuantity" : //  todo UCUM
                {
                  "value" : 1.25,
                  "unit" : "% w/v"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:54aa47fd-9964-5f97-6495-b2bec7f161e8",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "54aa47fd-9964-5f97-6495-b2bec7f161e8",
            "text" : // growthPromotion1
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_54aa47fd-9964-5f97-6495-b2bec7f161e8\"> </a><p><b>Generated Narrative: Observation</b><a name=\"54aa47fd-9964-5f97-6495-b2bec7f161e8\"> </a><a name=\"hc54aa47fd-9964-5f97-6495-b2bec7f161e8\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;54aa47fd-9964-5f97-6495-b2bec7f161e8&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/64515b3c-5134-448a-9d19-939ce1958524</p><p><b>status</b>: final</p><p><b>code</b>: Growth Promotion <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#GrowthPromotion)</span></p><p><b>subject</b>: See on this page: Procedure/44aa47fd-8964-5f96-8495-b2bec7f161a8</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><blockquote><p><b>component</b></p><p><b>code</b>: Growth Promotion - Beginning <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Growth Promotion - Beginning)</span></p><p><b>value</b>: Pass</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Growth Promotion - End <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Growth Promotion - End)</span></p><p><b>value</b>: Pass</p></blockquote></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/64515b3c-5134-448a-9d19-939ce1958524"
            },
            "status" : "final",
            "code" : // ObservationDefinition/GrowthPromotion
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "GrowthPromotion",
                  "display" : "Growth Promotion"
                }
              ]
            },
            "subject" : {
              "reference" : "Procedure/44aa47fd-8964-5f96-8495-b2bec7f161a8"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Procedure/procedure-drug-pq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "component" : [
              // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Growth Promotion - Beginning",
                      "display" : "Growth Promotion - Beginning"
                    }
                  ]
                },
                "valueString" : "Pass"
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Growth Promotion - End",
                      "display" : "Growth Promotion - End"
                    }
                  ]
                },
                "valueString" : "Pass"
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:64aa47fd-8964-5f98-6495-b2bec7f161e8",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "64aa47fd-8964-5f98-6495-b2bec7f161e8",
            "text" : // growthPromotion2
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_64aa47fd-8964-5f98-6495-b2bec7f161e8\"> </a><p><b>Generated Narrative: Observation</b><a name=\"64aa47fd-8964-5f98-6495-b2bec7f161e8\"> </a><a name=\"hc64aa47fd-8964-5f98-6495-b2bec7f161e8\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;64aa47fd-8964-5f98-6495-b2bec7f161e8&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/64515b3c-5134-448a-9d19-939ce1958524</p><p><b>status</b>: final</p><p><b>code</b>: Growth Promotion <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#GrowthPromotion)</span></p><p><b>subject</b>: See on this page: Procedure/44aa47fd-8964-5f96-6495-b2bec7f162a8</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><blockquote><p><b>component</b></p><p><b>code</b>: Growth Promotion - Beginning <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Growth Promotion - Beginning)</span></p><p><b>value</b>: Pass</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Growth Promotion - End <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Growth Promotion - End)</span></p><p><b>value</b>: Pass</p></blockquote></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/64515b3c-5134-448a-9d19-939ce1958524"
            },
            "status" : "final",
            "code" : // ObservationDefinition/GrowthPromotion
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "GrowthPromotion",
                  "display" : "Growth Promotion"
                }
              ]
            },
            "subject" : {
              "reference" : "Procedure/44aa47fd-8964-5f96-6495-b2bec7f162a8"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Procedure/procedure-run-2
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "component" : [
              // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Growth Promotion - Beginning",
                      "display" : "Growth Promotion - Beginning"
                    }
                  ]
                },
                "valueString" : "Pass"
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Growth Promotion - End",
                      "display" : "Growth Promotion - End"
                    }
                  ]
                },
                "valueString" : "Pass"
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:74aa47fd-8964-5f99-7495-b2bec7f161e8",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "74aa47fd-8964-5f99-7495-b2bec7f161e8",
            "text" : // growthPromotion3
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_74aa47fd-8964-5f99-7495-b2bec7f161e8\"> </a><p><b>Generated Narrative: Observation</b><a name=\"74aa47fd-8964-5f99-7495-b2bec7f161e8\"> </a><a name=\"hc74aa47fd-8964-5f99-7495-b2bec7f161e8\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;74aa47fd-8964-5f99-7495-b2bec7f161e8&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/64515b3c-5134-448a-9d19-939ce1958524</p><p><b>status</b>: final</p><p><b>code</b>: Growth Promotion <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#GrowthPromotion)</span></p><p><b>subject</b>: See on this page: Procedure/44aa47fd-8964-5f96-6495-b2bec7f163a8</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><blockquote><p><b>component</b></p><p><b>code</b>: Growth Promotion - Beginning <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Growth Promotion - Beginning)</span></p><p><b>value</b>: Pass</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Growth Promotion - End <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Growth Promotion - End)</span></p><p><b>value</b>: Fail</p></blockquote></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/64515b3c-5134-448a-9d19-939ce1958524"
            },
            "status" : "final",
            "code" : // ObservationDefinition/GrowthPromotion
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "GrowthPromotion",
                  "display" : "Growth Promotion"
                }
              ]
            },
            "subject" : {
              "reference" : "Procedure/44aa47fd-8964-5f96-6495-b2bec7f163a8"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Procedure/procedure-run-3
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "component" : [
              // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Growth Promotion - Beginning",
                      "display" : "Growth Promotion - Beginning"
                    }
                  ]
                },
                "valueString" : "Pass"
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Growth Promotion - End",
                      "display" : "Growth Promotion - End"
                    }
                  ]
                },
                "valueString" : "Fail"
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:44aa47fd-8964-5f96-8495-b2bec7f161a8",
          "resource" : {
            "resourceType" : "Procedure",
            "id" : "44aa47fd-8964-5f96-8495-b2bec7f161a8",
            "text" : // procedure-drug-pq-ex1
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Procedure_44aa47fd-8964-5f96-8495-b2bec7f161a8\"> </a><p><b>Generated Narrative: Procedure</b><a name=\"44aa47fd-8964-5f96-8495-b2bec7f161a8\"> </a><a name=\"hc44aa47fd-8964-5f96-8495-b2bec7f161a8\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Procedure &quot;44aa47fd-8964-5f96-8495-b2bec7f161a8&quot; </p></div><p><b>identifier</b>: Run 1</p><p><b>status</b>: completed</p><p><b>code</b>: Media Challenge Run <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#MediaChallengeRun)</span></p><p><b>subject</b>: <span>: Drug product</span></p></div>"
            },
            "identifier" : [
              // <meta>
                        <profile value="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Procedure-drug-pq"/>
                    </meta>
              {
                "value" : "Run 1"
              }
            ],
            "status" : "completed",
            "code" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "MediaChallengeRun",
                  "display" : "Media Challenge Run"
                }
              ]
            },
            "subject" : //  only needed to suppress IG warning
            {
              "extension" : [
                {
                  "url" : "http://hl7.org/fhir/StructureDefinition/alternate-reference",
                  "valueReference" : {
                    "reference" : "MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"
                  }
                }
              ],
              "display" : "Drug product"
            }
          }
        },
        // MedicinalProductDefinition/medicinalproductdefinition-drug-product-pq-ex1
        {
          "fullUrl" : "urn:uuid:44aa47fd-8964-5f96-6495-b2bec7f162a8",
          "resource" : {
            "resourceType" : "Procedure",
            "id" : "44aa47fd-8964-5f96-6495-b2bec7f162a8",
            "text" : // procedure-run-2
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Procedure_44aa47fd-8964-5f96-6495-b2bec7f162a8\"> </a><p><b>Generated Narrative: Procedure</b><a name=\"44aa47fd-8964-5f96-6495-b2bec7f162a8\"> </a><a name=\"hc44aa47fd-8964-5f96-6495-b2bec7f162a8\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Procedure &quot;44aa47fd-8964-5f96-6495-b2bec7f162a8&quot; </p></div><p><b>identifier</b>: Run 2</p><p><b>status</b>: completed</p><p><b>code</b>: Media Challenge Run <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#MediaChallengeRun)</span></p><p><b>subject</b>: <span>: Drug product</span></p></div>"
            },
            "identifier" : [
              {
                "value" : "Run 2"
              }
            ],
            "status" : "completed",
            "code" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "MediaChallengeRun",
                  "display" : "Media Challenge Run"
                }
              ]
            },
            "subject" : //  only needed to suppress IG warning
            {
              "extension" : [
                {
                  "url" : "http://hl7.org/fhir/StructureDefinition/alternate-reference",
                  "valueReference" : {
                    "reference" : "MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"
                  }
                }
              ],
              "display" : "Drug product"
            }
          }
        },
        // MedicinalProductDefinition/medicinalproductdefinition-drug-product-pq-ex1
        {
          "fullUrl" : "urn:uuid:44aa47fd-8964-5f96-6495-b2bec7f163a8",
          "resource" : {
            "resourceType" : "Procedure",
            "id" : "44aa47fd-8964-5f96-6495-b2bec7f163a8",
            "text" : // procedure-run-3
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Procedure_44aa47fd-8964-5f96-6495-b2bec7f163a8\"> </a><p><b>Generated Narrative: Procedure</b><a name=\"44aa47fd-8964-5f96-6495-b2bec7f163a8\"> </a><a name=\"hc44aa47fd-8964-5f96-6495-b2bec7f163a8\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Procedure &quot;44aa47fd-8964-5f96-6495-b2bec7f163a8&quot; </p></div><p><b>identifier</b>: Run 3</p><p><b>status</b>: completed</p><p><b>code</b>: Media Challenge Run <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#MediaChallengeRun)</span></p><p><b>subject</b>: <span>: Drug product</span></p></div>"
            },
            "identifier" : [
              {
                "value" : "Run 3"
              }
            ],
            "status" : "completed",
            "code" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "MediaChallengeRun",
                  "display" : "Media Challenge Run"
                }
              ]
            },
            "subject" : //  only needed to suppress IG warning
            {
              "extension" : [
                {
                  "url" : "http://hl7.org/fhir/StructureDefinition/alternate-reference",
                  "valueReference" : {
                    "reference" : "MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"
                  }
                }
              ],
              "display" : "Drug product"
            }
          }
        },
        // MedicinalProductDefinition/medicinalproductdefinition-drug-product-pq-ex1
        {
          "fullUrl" : "urn:uuid:44aa47fd-8964-5f96-6495-c2bec7f163a8",
          "resource" : {
            "resourceType" : "Procedure",
            "id" : "44aa47fd-8964-5f96-6495-c2bec7f163a8",
            "text" : // procedure-drug-pq-ex2
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Procedure_44aa47fd-8964-5f96-6495-c2bec7f163a8\"> </a><p><b>Generated Narrative: Procedure</b><a name=\"44aa47fd-8964-5f96-6495-c2bec7f163a8\"> </a><a name=\"hc44aa47fd-8964-5f96-6495-c2bec7f163a8\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Procedure &quot;44aa47fd-8964-5f96-6495-c2bec7f163a8&quot; </p></div><p><b>status</b>: completed</p><p><b>code</b>: Lyophilization Homogeneneity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#LyophilizationHomogeneneity)</span></p><p><b>subject</b>: <span>: Drug batch</span></p><h3>Performers</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Actor</b></td></tr><tr><td style=\"display: none\">*</td><td><a name=\"hcdevice-nosubject\"> </a><blockquote><p/><p><a name=\"device-nosubject\"> </a></p><p><a name=\"hcdevice-nosubject\"> </a></p><h3>Definitions</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td>#DDLyo1</td></tr></table></blockquote></td></tr></table><hr/><blockquote><p><b>Generated Narrative: Device #device-nosubject</b><a name=\"device-nosubject\"> </a><a name=\"hcdevice-nosubject\"> </a></p><h3>Definitions</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td>#DDLyo1</td></tr></table></blockquote><hr/><blockquote><p><b>Generated Narrative: DeviceDefinition #DDLyo1</b><a name=\"DDLyo1\"> </a><a name=\"hcDDLyo1\"> </a></p><p><b>identifier</b>: Lyo 1</p></blockquote></div>"
            },
            "contained" : [
              {
                "resourceType" : "Device",
                "id" : "device-nosubject",
                "definition" : {
                  "reference" : {
                    "reference" : "#DDLyo1"
                  }
                }
              },
              {
                "resourceType" : "DeviceDefinition",
                "id" : "DDLyo1",
                "identifier" : [
                  {
                    "value" : "Lyo 1"
                  }
                ]
              }
            ],
            "status" : "completed",
            "code" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "LyophilizationHomogeneneity",
                  "display" : "Lyophilization Homogeneneity"
                }
              ]
            },
            "subject" : //  only needed to suppress IG warning
            {
              "extension" : [
                {
                  "url" : "http://hl7.org/fhir/StructureDefinition/alternate-reference",
                  "valueReference" : {
                    "reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
                  }
                }
              ],
              "display" : "Drug batch"
            },
            "performer" : [
              // Medication/medication-batch-information-drug-pq-ex1
              {
                "actor" : {
                  "reference" : "#device-nosubject",
                  "display" : "Lyo 1"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:44aa47fd-8964-5f96-6495-b2bec7f161e7",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "44aa47fd-8964-5f96-6495-b2bec7f161e7",
            "text" : // postFiltrationFilterIntegrity1
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_44aa47fd-8964-5f96-6495-b2bec7f161e7\"> </a><p><b>Generated Narrative: Observation</b><a name=\"44aa47fd-8964-5f96-6495-b2bec7f161e7\"> </a><a name=\"hc44aa47fd-8964-5f96-6495-b2bec7f161e7\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;44aa47fd-8964-5f96-6495-b2bec7f161e7&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/75515b3c-5134-448a-9c19-949ce1958434</p><p><b>status</b>: final</p><p><b>code</b>: Post-filtration Filter Integrity (psig) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Post-filtration Filter Integrity (psig))</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 280 mOsm/kg</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Test Success <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#test-success)</span></td><td>Pass <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/75515b3c-5134-448a-9c19-949ce1958434"
            },
            "status" : "final",
            "code" : // ObservationDefinition/PostFiltrationFilterIntegrity
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Post-filtration Filter Integrity (psig)",
                  "display" : "Post-filtration Filter Integrity (psig)"
                }
              ],
              "text" : "Post-filtration Filter Integrity (psig)"
            },
            "subject" : {
              "reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Medication/medication-batch-information-drug-pq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 280,
              "unit" : "mOsm/kg"
            },
            "component" : [
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "test-success",
                      "display" : "Test Success"
                    }
                  ]
                },
                "valueCodeableConcept" : //  consider a boolean
                {
                  "text" : "Pass"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:44aa47fd-8964-4f96-6495-b2bec7f161e7",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "44aa47fd-8964-4f96-6495-b2bec7f161e7",
            "text" : // osmolality1
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_44aa47fd-8964-4f96-6495-b2bec7f161e7\"> </a><p><b>Generated Narrative: Observation</b><a name=\"44aa47fd-8964-4f96-6495-b2bec7f161e7\"> </a><a name=\"hc44aa47fd-8964-4f96-6495-b2bec7f161e7\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;44aa47fd-8964-4f96-6495-b2bec7f161e7&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/64525a3c-5034-448a-9c19-938ce1958424</p><p><b>status</b>: final</p><p><b>code</b>: osmolality <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Osmolality &quot;Osmolality&quot;)</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 280 mOsm/kg</p></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/64525a3c-5034-448a-9c19-938ce1958424"
            },
            "status" : "final",
            "code" : // ObservationDefinition/Osmolality
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Osmolality",
                  "display" : "Osmolality"
                }
              ],
              "text" : "osmolality"
            },
            "subject" : {
              "reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Medication/medication-batch-information-drug-pq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 280,
              "unit" : "mOsm/kg"
            }
          }
        },
        {
          "fullUrl" : "urn:uuid:54aa47fd-8964-4f96-6495-b2bec7f162e7",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "54aa47fd-8964-4f96-6495-b2bec7f162e7",
            "text" : // osmolality2
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_54aa47fd-8964-4f96-6495-b2bec7f162e7\"> </a><p><b>Generated Narrative: Observation</b><a name=\"54aa47fd-8964-4f96-6495-b2bec7f162e7\"> </a><a name=\"hc54aa47fd-8964-4f96-6495-b2bec7f162e7\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;54aa47fd-8964-4f96-6495-b2bec7f162e7&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/64525a3c-5034-448a-9c19-938ce1958424</p><p><b>status</b>: final</p><p><b>code</b>: osmolality <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Osmolality &quot;Osmolality&quot;)</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 285 mOsm/kg</p></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/64525a3c-5034-448a-9c19-938ce1958424"
            },
            "status" : "final",
            "code" : // ObservationDefinition/Osmolality
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Osmolality",
                  "display" : "Osmolality"
                }
              ],
              "text" : "osmolality"
            },
            "subject" : {
              "reference" : "Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Medication/medication-actual-batch-2
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 285,
              "unit" : "mOsm/kg"
            }
          }
        },
        {
          "fullUrl" : "urn:uuid:54aa48fd-8964-4f96-6495-b2bec7f163e7",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "54aa48fd-8964-4f96-6495-b2bec7f163e7",
            "text" : // osmolality3
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_54aa48fd-8964-4f96-6495-b2bec7f163e7\"> </a><p><b>Generated Narrative: Observation</b><a name=\"54aa48fd-8964-4f96-6495-b2bec7f163e7\"> </a><a name=\"hc54aa48fd-8964-4f96-6495-b2bec7f163e7\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;54aa48fd-8964-4f96-6495-b2bec7f163e7&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/64525a3c-5034-448a-9c19-938ce1958424</p><p><b>status</b>: final</p><p><b>code</b>: osmolality <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Osmolality &quot;Osmolality&quot;)</span></p><p><b>subject</b>: See on this page: Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 290 mOsm/kg</p></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/64525a3c-5034-448a-9c19-938ce1958424"
            },
            "status" : "final",
            "code" : // ObservationDefinition/Osmolality
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Osmolality",
                  "display" : "Osmolality"
                }
              ],
              "text" : "osmolality"
            },
            "subject" : {
              "reference" : "Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Medication/medication-actual-batch-3
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 290,
              "unit" : "mOsm/kg"
            }
          }
        },
        {
          "fullUrl" : "urn:uuid:44ba47fd-8964-4f96-6495-b2bec7f161e8",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "44ba47fd-8964-4f96-6495-b2bec7f161e8",
            "text" : // residualMoisture1
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_44ba47fd-8964-4f96-6495-b2bec7f161e8\"> </a><p><b>Generated Narrative: Observation</b><a name=\"44ba47fd-8964-4f96-6495-b2bec7f161e8\"> </a><a name=\"hc44ba47fd-8964-4f96-6495-b2bec7f161e8\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;44ba47fd-8964-4f96-6495-b2bec7f161e8&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/fc27b6d6-9fe2-91c2-2d16-47cb5b295e72</p><p><b>status</b>: final</p><p><b>code</b>: Residual Moisture (%) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Residual Moisture &quot;Residual Moisture&quot;)</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><blockquote><p><b>component</b></p><p><b>code</b>: Residual Moisture - Min <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Residual Moisture - Min)</span></p><p><b>value</b>: 3.1 %</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Residual Moisture - Max <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Residual Moisture - Max)</span></p><p><b>value</b>: 3.2 %</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Number of Samples <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SAMP)</span></p><p><b>value</b>: 2</p></blockquote></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/fc27b6d6-9fe2-91c2-2d16-47cb5b295e72"
            },
            "status" : "final",
            "code" : // ObservationDefinition/ResidualMoisture
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Residual Moisture",
                  "display" : "Residual Moisture"
                }
              ],
              "text" : "Residual Moisture (%)"
            },
            "subject" : {
              "reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Medication/medication-batch-information-drug-pq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "component" : [
              // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Residual Moisture - Min",
                      "display" : "Residual Moisture - Min"
                    }
                  ]
                },
                "valueQuantity" : {
                  "value" : 3.1,
                  "unit" : "%"
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Residual Moisture - Max",
                      "display" : "Residual Moisture - Max"
                    }
                  ]
                },
                "valueQuantity" : {
                  "value" : 3.2,
                  "unit" : "%"
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "SAMP",
                      "display" : "Number of Samples"
                    }
                  ]
                },
                "valueInteger" : 2
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:44ba47fd-9964-4f96-6495-b2bec7f161e8",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "44ba47fd-9964-4f96-6495-b2bec7f161e8",
            "text" : // residualMoisture2
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_44ba47fd-9964-4f96-6495-b2bec7f161e8\"> </a><p><b>Generated Narrative: Observation</b><a name=\"44ba47fd-9964-4f96-6495-b2bec7f161e8\"> </a><a name=\"hc44ba47fd-9964-4f96-6495-b2bec7f161e8\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;44ba47fd-9964-4f96-6495-b2bec7f161e8&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/fc27b6d6-9fe2-91c2-2d16-47cb5b295e72</p><p><b>status</b>: final</p><p><b>code</b>: Residual Moisture (%) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Residual Moisture &quot;Residual Moisture&quot;)</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 4.2 %</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Number of Samples <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SAMP)</span></td><td>3</td></tr></table></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/fc27b6d6-9fe2-91c2-2d16-47cb5b295e72"
            },
            "status" : "final",
            "code" : // ObservationDefinition/ResidualMoisture
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Residual Moisture",
                  "display" : "Residual Moisture"
                }
              ],
              "text" : "Residual Moisture (%)"
            },
            "subject" : {
              "reference" : "Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Medication/medication-actual-batch-2
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 4.2,
              "unit" : "%"
            },
            "component" : [
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "SAMP",
                      "display" : "Number of Samples"
                    }
                  ]
                },
                "valueInteger" : 3
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:44ba47fd-9964-4f96-6496-b2bec7f161e8",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "44ba47fd-9964-4f96-6496-b2bec7f161e8",
            "text" : // residualMoisture3
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_44ba47fd-9964-4f96-6496-b2bec7f161e8\"> </a><p><b>Generated Narrative: Observation</b><a name=\"44ba47fd-9964-4f96-6496-b2bec7f161e8\"> </a><a name=\"hc44ba47fd-9964-4f96-6496-b2bec7f161e8\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;44ba47fd-9964-4f96-6496-b2bec7f161e8&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/fc27b6d6-9fe2-91c2-2d16-47cb5b295e72</p><p><b>status</b>: final</p><p><b>code</b>: Residual Moisture (%) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Residual Moisture &quot;Residual Moisture&quot;)</span></p><p><b>subject</b>: See on this page: Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 4.4 %</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Number of Samples <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SAMP)</span></td><td>3</td></tr></table></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/fc27b6d6-9fe2-91c2-2d16-47cb5b295e72"
            },
            "status" : "final",
            "code" : // ObservationDefinition/ResidualMoisture
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Residual Moisture",
                  "display" : "Residual Moisture"
                }
              ],
              "text" : "Residual Moisture (%)"
            },
            "subject" : {
              "reference" : "Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Medication/medication-actual-batch-3
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 4.4,
              "unit" : "%"
            },
            "component" : [
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "SAMP",
                      "display" : "Number of Samples"
                    }
                  ]
                },
                "valueInteger" : 3
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:44ba47fd-8964-4f96-6495-b2bec7f161e7",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "44ba47fd-8964-4f96-6495-b2bec7f161e7",
            "text" : // SE-UHPLCMainPeak1
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_44ba47fd-8964-4f96-6495-b2bec7f161e7\"> </a><p><b>Generated Narrative: Observation</b><a name=\"44ba47fd-8964-4f96-6495-b2bec7f161e7\"> </a><a name=\"hc44ba47fd-8964-4f96-6495-b2bec7f161e7\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;44ba47fd-8964-4f96-6495-b2bec7f161e7&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/64525a3d-5034-448a-9c19-938ce1958424</p><p><b>status</b>: final</p><p><b>code</b>: SE-UHPLC Main Peak (%) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SE-UHPLCMainPeak &quot;SE-UHPLC Main Peak&quot;)</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><blockquote><p><b>component</b></p><p><b>code</b>: SE-UHPLC Main Peak - Beginning <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SE-UHPLC Main Peak - Beginning)</span></p><p><b>value</b>: 8.0 %</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: SE-UHPLC Main Peak - End <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SE-UHPLC Main Peak - End)</span></p><p><b>value</b>: 8.5 %</p></blockquote></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/64525a3d-5034-448a-9c19-938ce1958424"
            },
            "status" : "final",
            "code" : // ObservationDefinition/SE-UHPLCMainPeak
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "SE-UHPLCMainPeak",
                  "display" : "SE-UHPLC Main Peak"
                }
              ],
              "text" : "SE-UHPLC Main Peak (%)"
            },
            "subject" : {
              "reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Medication/medication-batch-information-drug-pq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "component" : [
              // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "SE-UHPLC Main Peak - Beginning",
                      "display" : "SE-UHPLC Main Peak - Beginning"
                    }
                  ]
                },
                "valueQuantity" : {
                  "value" : 8.0,
                  "unit" : "%"
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "SE-UHPLC Main Peak - End",
                      "display" : "SE-UHPLC Main Peak - End"
                    }
                  ]
                },
                "valueQuantity" : {
                  "value" : 8.5,
                  "unit" : "%"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:54ca47fd-8964-4f96-6495-b2bec7f162e7",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "54ca47fd-8964-4f96-6495-b2bec7f162e7",
            "text" : // SE-UHPLCMainPeak2
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_54ca47fd-8964-4f96-6495-b2bec7f162e7\"> </a><p><b>Generated Narrative: Observation</b><a name=\"54ca47fd-8964-4f96-6495-b2bec7f162e7\"> </a><a name=\"hc54ca47fd-8964-4f96-6495-b2bec7f162e7\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;54ca47fd-8964-4f96-6495-b2bec7f162e7&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/64525a3d-5034-448a-9c19-938ce1958424</p><p><b>status</b>: final</p><p><b>code</b>: SE-UHPLC Main Peak (%) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SE-UHPLCMainPeak &quot;SE-UHPLC Main Peak&quot;)</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><blockquote><p><b>component</b></p><p><b>code</b>: SE-UHPLC Main Peak - Beginning <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SE-UHPLC Main Peak - Beginning)</span></p><p><b>value</b>: 9.0 %</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: SE-UHPLC Main Peak - End <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SE-UHPLC Main Peak - End)</span></p><p><b>value</b>: 9.5 %</p></blockquote></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/64525a3d-5034-448a-9c19-938ce1958424"
            },
            "status" : "final",
            "code" : // ObservationDefinition/SE-UHPLCMainPeak
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "SE-UHPLCMainPeak",
                  "display" : "SE-UHPLC Main Peak"
                }
              ],
              "text" : "SE-UHPLC Main Peak (%)"
            },
            "subject" : {
              "reference" : "Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Medication/medication-actual-batch-2
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "component" : [
              // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "SE-UHPLC Main Peak - Beginning",
                      "display" : "SE-UHPLC Main Peak - Beginning"
                    }
                  ]
                },
                "valueQuantity" : {
                  "value" : 9.0,
                  "unit" : "%"
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "SE-UHPLC Main Peak - End",
                      "display" : "SE-UHPLC Main Peak - End"
                    }
                  ]
                },
                "valueQuantity" : {
                  "value" : 9.5,
                  "unit" : "%"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:54da48fd-8964-4f96-6495-b2bec7f163e7",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "54da48fd-8964-4f96-6495-b2bec7f163e7",
            "text" : // SE-UHPLCMainPeak3
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_54da48fd-8964-4f96-6495-b2bec7f163e7\"> </a><p><b>Generated Narrative: Observation</b><a name=\"54da48fd-8964-4f96-6495-b2bec7f163e7\"> </a><a name=\"hc54da48fd-8964-4f96-6495-b2bec7f163e7\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;54da48fd-8964-4f96-6495-b2bec7f163e7&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/64525a3d-5034-448a-9c19-938ce1958424</p><p><b>status</b>: final</p><p><b>code</b>: SE-UHPLC Main Peak (%) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SE-UHPLCMainPeak &quot;SE-UHPLC Main Peak&quot;)</span></p><p><b>subject</b>: See on this page: Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><blockquote><p><b>component</b></p><p><b>code</b>: SE-UHPLC Main Peak - Beginning <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SE-UHPLC Main Peak - Beginning)</span></p><p><b>value</b>: 10.0 %</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: SE-UHPLC Main Peak - End <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SE-UHPLC Main Peak - End)</span></p><p><b>value</b>: 10.5 %</p></blockquote></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/64525a3d-5034-448a-9c19-938ce1958424"
            },
            "status" : "final",
            "code" : // ObservationDefinition/SE-UHPLCMainPeak
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "SE-UHPLCMainPeak",
                  "display" : "SE-UHPLC Main Peak"
                }
              ],
              "text" : "SE-UHPLC Main Peak (%)"
            },
            "subject" : {
              "reference" : "Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Medication/medication-actual-batch-3
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "component" : [
              // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "SE-UHPLC Main Peak - Beginning",
                      "display" : "SE-UHPLC Main Peak - Beginning"
                    }
                  ]
                },
                "valueQuantity" : {
                  "value" : 10.0,
                  "unit" : "%"
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "SE-UHPLC Main Peak - End",
                      "display" : "SE-UHPLC Main Peak - End"
                    }
                  ]
                },
                "valueQuantity" : {
                  "value" : 10.5,
                  "unit" : "%"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:44ba47fd-8964-5f96-6495-b2bec7f161e7",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "44ba47fd-8964-5f96-6495-b2bec7f161e7",
            "text" : // SE-UHPLCMainPeakGraph1
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_44ba47fd-8964-5f96-6495-b2bec7f161e7\"> </a><p><b>Generated Narrative: Observation</b><a name=\"44ba47fd-8964-5f96-6495-b2bec7f161e7\"> </a><a name=\"hc44ba47fd-8964-5f96-6495-b2bec7f161e7\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;44ba47fd-8964-5f96-6495-b2bec7f161e7&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/64525a4d-5034-448a-9c19-938ce1958424</p><p><b>status</b>: final</p><p><b>code</b>: SE-UHPLC Main Peak (Graph) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SE-UHPLCMainPeak &quot;SE-UHPLC Main Peak&quot;)</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: </p></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/64525a4d-5034-448a-9c19-938ce1958424"
            },
            "status" : "final",
            "code" : // ObservationDefinition/SE-UHPLCMainPeakGraph
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "SE-UHPLCMainPeak",
                  "display" : "SE-UHPLC Main Peak"
                }
              ],
              "text" : "SE-UHPLC Main Peak (Graph)"
            },
            "subject" : {
              "reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Medication/medication-batch-information-drug-pq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueAttachment" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "contentType" : "image/png",
              "data" : " "
            }
          }
        },
        {
          "fullUrl" : "urn:uuid:54ba47fd-8964-4f96-6495-b2bec7f161e7",
          "resource" : // component> these are now done in another non-batch specific obs
          {
            "resourceType" : "Observation",
            "id" : "54ba47fd-8964-4f96-6495-b2bec7f161e7",
            "text" : // SE-UHPLCMainPeakLyoph1
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_54ba47fd-8964-4f96-6495-b2bec7f161e7\"> </a><p><b>Generated Narrative: Observation</b><a name=\"54ba47fd-8964-4f96-6495-b2bec7f161e7\"> </a><a name=\"hc54ba47fd-8964-4f96-6495-b2bec7f161e7\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;54ba47fd-8964-4f96-6495-b2bec7f161e7&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/64525a3d-5134-448a-9c19-938ce1958424</p><p><b>status</b>: final</p><p><b>code</b>: SE-UHPLC Main Peak (%) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SE-UHPLCMainPeak &quot;SE-UHPLC Main Peak&quot;)</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 91 %</p></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/64525a3d-5134-448a-9c19-938ce1958424"
            },
            "status" : "final",
            "code" : // ObservationDefinition/SE-UHPLCMainPeakLyoph
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "SE-UHPLCMainPeak",
                  "display" : "SE-UHPLC Main Peak"
                }
              ],
              "text" : "SE-UHPLC Main Peak (%)"
            },
            "subject" : {
              "reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Medication/medication-batch-information-drug-pq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 91,
              "unit" : "%"
            }
          }
        },
        {
          "fullUrl" : "urn:uuid:54ba47fd-8964-4f96-6495-b2bec7f161e8",
          "resource" : // component> these are now done in another non-batch specific obs
          {
            "resourceType" : "Observation",
            "id" : "54ba47fd-8964-4f96-6495-b2bec7f161e8",
            "text" : // SE-UHPLCMainPeakLyoph2
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_54ba47fd-8964-4f96-6495-b2bec7f161e8\"> </a><p><b>Generated Narrative: Observation</b><a name=\"54ba47fd-8964-4f96-6495-b2bec7f161e8\"> </a><a name=\"hc54ba47fd-8964-4f96-6495-b2bec7f161e8\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;54ba47fd-8964-4f96-6495-b2bec7f161e8&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/64525a3d-5134-448a-9c19-938ce1958424</p><p><b>status</b>: final</p><p><b>code</b>: SE-UHPLC Main Peak (%) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SE-UHPLCMainPeak &quot;SE-UHPLC Main Peak&quot;)</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 89 %</p></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/64525a3d-5134-448a-9c19-938ce1958424"
            },
            "status" : "final",
            "code" : // ObservationDefinition/SE-UHPLCMainPeakLyoph
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "SE-UHPLCMainPeak",
                  "display" : "SE-UHPLC Main Peak"
                }
              ],
              "text" : "SE-UHPLC Main Peak (%)"
            },
            "subject" : {
              "reference" : "Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Medication/medication-actual-batch-2
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 89,
              "unit" : "%"
            }
          }
        },
        {
          "fullUrl" : "urn:uuid:54ba47fd-8964-4f96-6495-b2bec7f161e9",
          "resource" : // component> these are now done in another non-batch specific obs
          {
            "resourceType" : "Observation",
            "id" : "54ba47fd-8964-4f96-6495-b2bec7f161e9",
            "text" : // SE-UHPLCMainPeakLyoph3
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_54ba47fd-8964-4f96-6495-b2bec7f161e9\"> </a><p><b>Generated Narrative: Observation</b><a name=\"54ba47fd-8964-4f96-6495-b2bec7f161e9\"> </a><a name=\"hc54ba47fd-8964-4f96-6495-b2bec7f161e9\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;54ba47fd-8964-4f96-6495-b2bec7f161e9&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/64525a3d-5134-448a-9c19-938ce1958424</p><p><b>status</b>: final</p><p><b>code</b>: SE-UHPLC Main Peak (%) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SE-UHPLCMainPeak &quot;SE-UHPLC Main Peak&quot;)</span></p><p><b>subject</b>: See on this page: Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 92 %</p></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/64525a3d-5134-448a-9c19-938ce1958424"
            },
            "status" : "final",
            "code" : // ObservationDefinition/SE-UHPLCMainPeakLyoph
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "SE-UHPLCMainPeak",
                  "display" : "SE-UHPLC Main Peak"
                }
              ],
              "text" : "SE-UHPLC Main Peak (%)"
            },
            "subject" : {
              "reference" : "Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Medication/medication-actual-batch-3
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 92,
              "unit" : "%"
            }
          }
        },
        {
          "fullUrl" : "urn:uuid:54ba48fd-8964-4f96-6495-b2bec7f161e7",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "54ba48fd-8964-4f96-6495-b2bec7f161e7",
            "text" : // SE-UHPLCMainPeakLyophConclusionObs
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_54ba48fd-8964-4f96-6495-b2bec7f161e7\"> </a><p><b>Generated Narrative: Observation</b><a name=\"54ba48fd-8964-4f96-6495-b2bec7f161e7\"> </a><a name=\"hc54ba48fd-8964-4f96-6495-b2bec7f161e7\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;54ba48fd-8964-4f96-6495-b2bec7f161e7&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/64525a3d-5134-448a-9c19-938ce1958424</p><p><b>status</b>: final</p><p><b>code</b>: SE-UHPLC Main Peak (%) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SE-UHPLCMainPeak &quot;SE-UHPLC Main Peak&quot;)</span></p><p><b>subject</b>: <span>: Product</span></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><blockquote><p><b>component</b></p><p><b>code</b>: Number of Samples <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SAMP)</span></p><p><b>value</b>: 12</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: SE-UHPLC Main Peak Conclusion <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SE-UHPLCMainPeak - Conclusion &quot;SE-UHPLC Main Peak - Conclusion&quot;)</span></p><p><b>value</b>: Pass</p></blockquote></div>"
            },
            "instantiatesReference" : //  not using a separate one, % and conclusion are in one definition
            {
              "reference" : "ObservationDefinition/64525a3d-5134-448a-9c19-938ce1958424"
            },
            "status" : "final",
            "code" : // ObservationDefinition/SE-UHPLCMainPeakLyoph
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "SE-UHPLCMainPeak",
                  "display" : "SE-UHPLC Main Peak"
                }
              ],
              "text" : "SE-UHPLC Main Peak (%)"
            },
            "subject" : //  note no value here, because the code us the %. But this obs is really about the conclusion
            //  note no subject here because there is not one specific batch
            //  added only to keep IG happy
            {
              "extension" : [
                {
                  "url" : "http://hl7.org/fhir/StructureDefinition/data-absent-reason",
                  "valueCode" : "unsupported"
                }
              ],
              "display" : "Product"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "component" : [
              // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "SAMP",
                      "display" : "Number of Samples"
                    }
                  ]
                },
                "valueInteger" : 12
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "SE-UHPLCMainPeak - Conclusion",
                      "display" : "SE-UHPLC Main Peak - Conclusion"
                    }
                  ],
                  "text" : "SE-UHPLC Main Peak Conclusion"
                },
                "valueString" : "Pass"
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:54bb47fd-8964-4f96-6495-b2bec7f161e7",
          "resource" : // component> these are now done in another non-batch specific obs
          {
            "resourceType" : "Observation",
            "id" : "54bb47fd-8964-4f96-6495-b2bec7f161e7",
            "text" : // SE-UHPLCHMWLyoph1
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_54bb47fd-8964-4f96-6495-b2bec7f161e7\"> </a><p><b>Generated Narrative: Observation</b><a name=\"54bb47fd-8964-4f96-6495-b2bec7f161e7\"> </a><a name=\"hc54bb47fd-8964-4f96-6495-b2bec7f161e7\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;54bb47fd-8964-4f96-6495-b2bec7f161e7&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/64525a3d-5144-448a-9c19-938ce1958424</p><p><b>status</b>: final</p><p><b>code</b>: SE-UHPLC HMW (%) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SE-UHPLCHMW &quot;SE-UHPLC HMW&quot;)</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 88 %</p></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/64525a3d-5144-448a-9c19-938ce1958424"
            },
            "status" : "final",
            "code" : // ObservationDefinition/SE-UHPLCHMWLyoph
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "SE-UHPLCHMW",
                  "display" : "SE-UHPLC HMW"
                }
              ],
              "text" : "SE-UHPLC HMW (%)"
            },
            "subject" : {
              "reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Medication/medication-batch-information-drug-pq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 88,
              "unit" : "%"
            }
          }
        },
        {
          "fullUrl" : "urn:uuid:54ba47fd-9964-4f96-6495-b2bec7f161e8",
          "resource" : // component> these are now done in another non-batch specific obs
          {
            "resourceType" : "Observation",
            "id" : "54ba47fd-9964-4f96-6495-b2bec7f161e8",
            "text" : // SE-UHPLCHMWLyoph2
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_54ba47fd-9964-4f96-6495-b2bec7f161e8\"> </a><p><b>Generated Narrative: Observation</b><a name=\"54ba47fd-9964-4f96-6495-b2bec7f161e8\"> </a><a name=\"hc54ba47fd-9964-4f96-6495-b2bec7f161e8\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;54ba47fd-9964-4f96-6495-b2bec7f161e8&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/64525a3d-5144-448a-9c19-938ce1958424</p><p><b>status</b>: final</p><p><b>code</b>: SE-UHPLC HMW (%) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SE-UHPLCHMW &quot;SE-UHPLC HMW&quot;)</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 93 %</p></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/64525a3d-5144-448a-9c19-938ce1958424"
            },
            "status" : "final",
            "code" : // ObservationDefinition/SE-UHPLCHMWLyoph
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "SE-UHPLCHMW",
                  "display" : "SE-UHPLC HMW"
                }
              ],
              "text" : "SE-UHPLC HMW (%)"
            },
            "subject" : {
              "reference" : "Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Medication/medication-actual-batch-2
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 93,
              "unit" : "%"
            }
          }
        },
        {
          "fullUrl" : "urn:uuid:54ba47fe-8964-4f96-6495-b2bec7f161e9",
          "resource" : // component> these are now done in another non-batch specific obs
          {
            "resourceType" : "Observation",
            "id" : "54ba47fe-8964-4f96-6495-b2bec7f161e9",
            "text" : // SE-UHPLCHMWLyoph3
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_54ba47fe-8964-4f96-6495-b2bec7f161e9\"> </a><p><b>Generated Narrative: Observation</b><a name=\"54ba47fe-8964-4f96-6495-b2bec7f161e9\"> </a><a name=\"hc54ba47fe-8964-4f96-6495-b2bec7f161e9\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;54ba47fe-8964-4f96-6495-b2bec7f161e9&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/64525a3d-5144-448a-9c19-938ce1958424</p><p><b>status</b>: final</p><p><b>code</b>: SE-UHPLC HMW (%) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SE-UHPLCHMW &quot;SE-UHPLC HMW&quot;)</span></p><p><b>subject</b>: See on this page: Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><p><b>value</b>: 99 %</p></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/64525a3d-5144-448a-9c19-938ce1958424"
            },
            "status" : "final",
            "code" : // ObservationDefinition/SE-UHPLCHMWLyoph
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "SE-UHPLCHMW",
                  "display" : "SE-UHPLC HMW"
                }
              ],
              "text" : "SE-UHPLC HMW (%)"
            },
            "subject" : {
              "reference" : "Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Medication/medication-actual-batch-3
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "valueQuantity" : // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
            {
              "value" : 99,
              "unit" : "%"
            }
          }
        },
        {
          "fullUrl" : "urn:uuid:64ba48fd-8964-4f96-6495-b2bec7f161e7",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "64ba48fd-8964-4f96-6495-b2bec7f161e7",
            "text" : // SE-UHPLCHMWLyophConclusionObs
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_64ba48fd-8964-4f96-6495-b2bec7f161e7\"> </a><p><b>Generated Narrative: Observation</b><a name=\"64ba48fd-8964-4f96-6495-b2bec7f161e7\"> </a><a name=\"hc64ba48fd-8964-4f96-6495-b2bec7f161e7\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;64ba48fd-8964-4f96-6495-b2bec7f161e7&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/64525a3d-5144-448a-9c19-938ce1958424</p><p><b>status</b>: final</p><p><b>code</b>: SE-UHPLC HMW (%) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SE-UHPLCHMW &quot;SE-UHPLC HMW&quot;)</span></p><p><b>subject</b>: <span>: Product</span></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><blockquote><p><b>component</b></p><p><b>code</b>: Number of Samples <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SAMP)</span></p><p><b>value</b>: 9</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: SE-UHPLC HMW Conclusion <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SE-UHPLCHMWPeak - Conclusion &quot;SE-UHPLC HMW Peak - Conclusion&quot;)</span></p><p><b>value</b>: Fail</p></blockquote></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/64525a3d-5144-448a-9c19-938ce1958424"
            },
            "status" : "final",
            "code" : // ObservationDefinition/SE-UHPLCHMWLyoph
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "SE-UHPLCHMW",
                  "display" : "SE-UHPLC HMW"
                }
              ],
              "text" : "SE-UHPLC HMW (%)"
            },
            "subject" : //  note no value here, because the code us the %. But this obs is really about the conclusion
            //  not one specific batch
            //  no subject because it applies to all the samples
            //  added only to keep IG happy
            {
              "extension" : [
                {
                  "url" : "http://hl7.org/fhir/StructureDefinition/data-absent-reason",
                  "valueCode" : "unsupported"
                }
              ],
              "display" : "Product"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "component" : [
              // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "SAMP",
                      "display" : "Number of Samples"
                    }
                  ]
                },
                "valueInteger" : 9
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "SE-UHPLCHMWPeak - Conclusion",
                      "display" : "SE-UHPLC HMW Peak - Conclusion"
                    }
                  ],
                  "text" : "SE-UHPLC HMW Conclusion"
                },
                "valueString" : "Fail"
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:44ba47fd-8964-4f97-6495-b2bec7f161e7",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "44ba47fd-8964-4f97-6495-b2bec7f161e7",
            "text" : // SE-UHPLCHMW1
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_44ba47fd-8964-4f97-6495-b2bec7f161e7\"> </a><p><b>Generated Narrative: Observation</b><a name=\"44ba47fd-8964-4f97-6495-b2bec7f161e7\"> </a><a name=\"hc44ba47fd-8964-4f97-6495-b2bec7f161e7\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;44ba47fd-8964-4f97-6495-b2bec7f161e7&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/64525a33-5034-448a-9c19-938ce1958424</p><p><b>status</b>: final</p><p><b>code</b>: SE-UHPLC HMW (%) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SE-UHPLCHMW &quot;SE-UHPLC HMW&quot;)</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><blockquote><p><b>component</b></p><p><b>code</b>: SE-UHPLC HMW - Beginning <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SE-UHPLCHMW - Beginning)</span></p><p><b>value</b>: 7.0 %</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: SE-UHPLC HMW - End <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SE-UHPLCHMW - End)</span></p><p><b>value</b>: 7.5 %</p></blockquote></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/64525a33-5034-448a-9c19-938ce1958424"
            },
            "status" : "final",
            "code" : // ObservationDefinition/SE-UHPLCHMW
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "SE-UHPLCHMW",
                  "display" : "SE-UHPLC HMW"
                }
              ],
              "text" : "SE-UHPLC HMW (%)"
            },
            "subject" : {
              "reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Medication/medication-batch-information-drug-pq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "component" : [
              // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "SE-UHPLCHMW - Beginning",
                      "display" : "SE-UHPLC HMW - Beginning"
                    }
                  ]
                },
                "valueQuantity" : {
                  "value" : 7.0,
                  "unit" : "%"
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "SE-UHPLCHMW - End",
                      "display" : "SE-UHPLC HMW - End"
                    }
                  ]
                },
                "valueQuantity" : {
                  "value" : 7.5,
                  "unit" : "%"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:54ca47fd-8964-4f98-6495-b2bec7f162e7",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "54ca47fd-8964-4f98-6495-b2bec7f162e7",
            "text" : // SE-UHPLCHMW2
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_54ca47fd-8964-4f98-6495-b2bec7f162e7\"> </a><p><b>Generated Narrative: Observation</b><a name=\"54ca47fd-8964-4f98-6495-b2bec7f162e7\"> </a><a name=\"hc54ca47fd-8964-4f98-6495-b2bec7f162e7\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;54ca47fd-8964-4f98-6495-b2bec7f162e7&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/64525a33-5034-448a-9c19-938ce1958424</p><p><b>status</b>: final</p><p><b>code</b>: SE-UHPLC HMW (%) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SE-UHPLCHMW &quot;SE-UHPLC HMW&quot;)</span></p><p><b>subject</b>: See on this page: Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><blockquote><p><b>component</b></p><p><b>code</b>: SE-UHPLC HMW - Beginning <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SE-UHPLCHMW - Beginning)</span></p><p><b>value</b>: 8.0 %</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: SE-UHPLC HMW - End <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SE-UHPLCHMW - End)</span></p><p><b>value</b>: 8.5 %</p></blockquote></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/64525a33-5034-448a-9c19-938ce1958424"
            },
            "status" : "final",
            "code" : // ObservationDefinition/SE-UHPLCHMW
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "SE-UHPLCHMW",
                  "display" : "SE-UHPLC HMW"
                }
              ],
              "text" : "SE-UHPLC HMW (%)"
            },
            "subject" : {
              "reference" : "Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Medication/medication-actual-batch-2
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "component" : [
              // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "SE-UHPLCHMW - Beginning",
                      "display" : "SE-UHPLC HMW - Beginning"
                    }
                  ]
                },
                "valueQuantity" : {
                  "value" : 8.0,
                  "unit" : "%"
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "SE-UHPLCHMW - End",
                      "display" : "SE-UHPLC HMW - End"
                    }
                  ]
                },
                "valueQuantity" : {
                  "value" : 8.5,
                  "unit" : "%"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:54da48fd-8964-4f99-6495-b2bec7f163e7",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "54da48fd-8964-4f99-6495-b2bec7f163e7",
            "text" : // SE-UHPLCHMW3
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_54da48fd-8964-4f99-6495-b2bec7f163e7\"> </a><p><b>Generated Narrative: Observation</b><a name=\"54da48fd-8964-4f99-6495-b2bec7f163e7\"> </a><a name=\"hc54da48fd-8964-4f99-6495-b2bec7f163e7\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;54da48fd-8964-4f99-6495-b2bec7f163e7&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/64525a33-5034-448a-9c19-938ce1958424</p><p><b>status</b>: final</p><p><b>code</b>: SE-UHPLC Main Peak (%) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SE-UHPLCHMW &quot;SE-UHPLC HMW&quot;)</span></p><p><b>subject</b>: See on this page: Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><blockquote><p><b>component</b></p><p><b>code</b>: SE-UHPLC HMW - Beginning <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SE-UHPLCHMW - Beginning)</span></p><p><b>value</b>: 9.0 %</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: SE-UHPLC HMW - End <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#SE-UHPLCHMW - End)</span></p><p><b>value</b>: 9.5 %</p></blockquote></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/64525a33-5034-448a-9c19-938ce1958424"
            },
            "status" : "final",
            "code" : // ObservationDefinition/SE-UHPLCHMW
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "SE-UHPLCHMW",
                  "display" : "SE-UHPLC HMW"
                }
              ],
              "text" : "SE-UHPLC Main Peak (%)"
            },
            "subject" : {
              "reference" : "Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Medication/medication-actual-batch-3
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "component" : [
              // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "SE-UHPLCHMW - Beginning",
                      "display" : "SE-UHPLC HMW - Beginning"
                    }
                  ]
                },
                "valueQuantity" : {
                  "value" : 9.0,
                  "unit" : "%"
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "SE-UHPLCHMW - End",
                      "display" : "SE-UHPLC HMW - End"
                    }
                  ]
                },
                "valueQuantity" : {
                  "value" : 9.5,
                  "unit" : "%"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:55aa47fd-9964-5f97-6495-b2bec7f161e8",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "55aa47fd-9964-5f97-6495-b2bec7f161e8",
            "text" : // fillWeight1
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Observation_55aa47fd-9964-5f97-6495-b2bec7f161e8\"> </a><p><b>Generated Narrative: Observation</b><a name=\"55aa47fd-9964-5f97-6495-b2bec7f161e8\"> </a><a name=\"hc55aa47fd-9964-5f97-6495-b2bec7f161e8\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;55aa47fd-9964-5f97-6495-b2bec7f161e8&quot; </p></div><p><b>instantiates</b>: See on this page: ObservationDefinition/64515b3c-5134-448a-9c19-939ce2958524</p><p><b>status</b>: final</p><p><b>code</b>: Fill Weight <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Fill Weight)</span></p><p><b>subject</b>: See on this page: Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51</p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: See on this page: Organization/378fbe5f-5926-3a5c-4c64-5428df877b08</p><blockquote><p><b>component</b></p><p><b>code</b>: Fill Weight - Minimum <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Fill Weight - Minimum)</span></p><p><b>value</b>: 9.90 g</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Fill Weight - Maximum <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Fill Weight - Maximum)</span></p><p><b>value</b>: 9.92 g</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Fill Weight - Mean <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#Fill Weight - Mean)</span></p><p><b>value</b>: 9.91 CFU/100 mL</p></blockquote></div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/64515b3c-5134-448a-9c19-939ce2958524"
            },
            "status" : "final",
            "code" : // ObservationDefinition/FillWeight
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "Fill Weight",
                  "display" : "Fill Weight"
                }
              ]
            },
            "subject" : {
              "reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              // Medication/medication-batch-information-drug-pq-ex1
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ],
            "component" : [
              // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Fill Weight - Minimum",
                      "display" : "Fill Weight - Minimum"
                    }
                  ]
                },
                "valueQuantity" : //  todo UCUM
                {
                  "value" : 9.90,
                  "unit" : "g"
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Fill Weight - Maximum",
                      "display" : "Fill Weight - Maximum"
                    }
                  ]
                },
                "valueQuantity" : //  todo UCUM
                {
                  "value" : 9.92,
                  "unit" : "g"
                }
              },
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                      "code" : "Fill Weight - Mean",
                      "display" : "Fill Weight - Mean"
                    }
                  ]
                },
                "valueQuantity" : //  todo UCUM
                {
                  "value" : 9.91,
                  "unit" : "CFU/100 mL"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:45aa47fd-8964-4f96-6495-b2bec7f160f7",
          "resource" : {
            "resourceType" : "Observation",
            "id" : "45aa47fd-8964-4f96-6495-b2bec7f160f7",
            "text" : // fillingHomogeneityConclusion-nosubject
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">\n                  <table>\n                     <tr>\n                        <th>Quality Attribute</th>\n                        <th>Justification</th>\n                        <th>Analytical Method</th>\n                     </tr>\n                     <tr>\n                        <td>Quantity</td>\n                        <td>Demonstrates that the drug product content is maintained throughout the filling process</td>\n                        <td>Protein concentration</td>\n                     </tr>\n                     <tr>\n                        <td>Purity</td>\n                        <td>Demonstrates the product quality is not adversely impacted over the duration of the fill through aggregation and / or oxidation</td>\n                        <td>SE-UHPLC</td>\n                     </tr>\n                     <tr>\n                        <td>Subvisible Particles</td>\n                        <td>Quantitatively determines that subvisible particle content is maintained within specification throughout the filling process</td>\n                        <td>Light obscuration</td>\n                     </tr>\n                  </table>\n               </div>"
            },
            "instantiatesReference" : {
              "reference" : "ObservationDefinition/22525a3c-5035-448a-9c19-938ce1958424"
            },
            "status" : "final",
            "code" : // ObservationDefinition/conclusionHomogeneity
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                  "code" : "CONC",
                  "display" : "Conclusion"
                }
              ],
              "text" : "Conclusion"
            },
            "subject" : //  no subject because it applies to all the samples
            //  added only to keep IG happy
            {
              "extension" : [
                {
                  "url" : "http://hl7.org/fhir/StructureDefinition/data-absent-reason",
                  "valueCode" : "unsupported"
                }
              ],
              "display" : "Product"
            },
            "effectiveDateTime" : "2023-01-01T12:00:00Z",
            "performer" : [
              {
                "reference" : "Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"
              }
            ]
          }
        },
        // Organization/378fbe5f-5926-3a5c-4c64-5428df877b08
        {
          "fullUrl" : "urn:uuid:a0694a7a-aafa-4cbe-8135-c788a9a4d3d5",
          "resource" : //  Section 1.1 - DP Identification
          {
            "resourceType" : "MedicinalProductDefinition",
            "id" : "a0694a7a-aafa-4cbe-8135-c788a9a4d3d5",
            "text" : // medicinalproductdefinition-drug-product-pq-ex1
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"MedicinalProductDefinition_a0694a7a-aafa-4cbe-8135-c788a9a4d3d5\"> </a><p><b>Generated Narrative: MedicinalProductDefinition</b><a name=\"a0694a7a-aafa-4cbe-8135-c788a9a4d3d5\"> </a><a name=\"hca0694a7a-aafa-4cbe-8135-c788a9a4d3d5\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource MedicinalProductDefinition &quot;a0694a7a-aafa-4cbe-8135-c788a9a4d3d5&quot; </p></div><p><b>description</b>: Textual description of the product</p><p><b>combinedPharmaceuticalDoseForm</b>: Gastro-resistant tablet <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (standardterms.edqm.eu#10225000)</span></p><p><b>route</b>: Oral use <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (standardterms.edqm.eu#20053000)</span></p><blockquote><p><b>name</b></p><p><b>productName</b>: Biocure</p><p><b>type</b>: Proprietary <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-productNameType-pq-example.html\">Product Name Type - example</a>#Proprietary)</span></p><h3>Parts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Part</b></td><td><b>Type</b></td></tr><tr><td style=\"display: none\">*</td><td>20mg</td><td>Strength part <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-medicinal-product-name-part-type.html\">Product Name Part Type</a>#StrengthPart)</span></td></tr></table></blockquote></div>"
            },
            "description" : "Textual description of the product",
            "combinedPharmaceuticalDoseForm" : {
              "coding" : [
                {
                  "system" : "http://standardterms.edqm.eu",
                  "code" : "10225000",
                  "display" : "Gastro-resistant tablet"
                }
              ]
            },
            "route" : [
              {
                "coding" : [
                  {
                    "system" : "http://standardterms.edqm.eu",
                    "code" : "20053000",
                    "display" : "Oral use"
                  }
                ]
              }
            ],
            "name" : [
              {
                "productName" : "Biocure",
                "type" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-productNameType-pq-example",
                      "code" : "Proprietary",
                      "display" : "Proprietary"
                    }
                  ]
                },
                "part" : [
                  {
                    "part" : "20mg",
                    "type" : {
                      "coding" : [
                        {
                          "system" : "http://hl7.org/fhir/medicinal-product-name-part-type",
                          "code" : "StrengthPart",
                          "display" : "Strength part"
                        }
                      ]
                    }
                  }
                ]
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:a0694a7a-aafa-4cbe-8135-c788a9a4d3d6",
          "resource" : {
            "resourceType" : "Ingredient",
            "id" : "a0694a7a-aafa-4cbe-8135-c788a9a4d3d6",
            "text" : // productIngredient
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Ingredient_a0694a7a-aafa-4cbe-8135-c788a9a4d3d6\"> </a><p><b>Generated Narrative: Ingredient</b><a name=\"a0694a7a-aafa-4cbe-8135-c788a9a4d3d6\"> </a><a name=\"hca0694a7a-aafa-4cbe-8135-c788a9a4d3d6\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Ingredient &quot;a0694a7a-aafa-4cbe-8135-c788a9a4d3d6&quot; </p></div><p><b>status</b>: active</p><p><b>for</b>: See on this page: MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5</p><p><b>role</b>: Active <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-ingredient-role.html\">Ingredient Role</a>#100000072072)</span></p><blockquote><p><b>substance</b></p><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td>See on this page: SubstanceDefinition/57a9af63-315d-1585-a261-0e337b289390</td></tr></table></blockquote></div>"
            },
            "status" : "active",
            "for" : [
              {
                "reference" : "MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"
              }
            ],
            "role" : // MedicinalProductDefinition/medicinalproductdefinition-drug-product-pq-ex1
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/ingredient-role",
                  "code" : "100000072072",
                  "display" : "Active"
                }
              ]
            },
            "substance" : {
              "code" : {
                "reference" : {
                  "reference" : "SubstanceDefinition/57a9af63-315d-1585-a261-0e337b289390"
                }
              }
            }
          }
        },
        // SubstanceDefinition/substancedefinition-component-substance-dxpq-ex1
        {
          "fullUrl" : "urn:uuid:57a9af63-315d-1585-a261-0e337b289390",
          "resource" : {
            "resourceType" : "SubstanceDefinition",
            "id" : "57a9af63-315d-1585-a261-0e337b289390",
            "text" : // substancedefinition-component-substance-dxpq-ex1
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"SubstanceDefinition_57a9af63-315d-1585-a261-0e337b289390\"> </a><p><b>Generated Narrative: SubstanceDefinition</b><a name=\"57a9af63-315d-1585-a261-0e337b289390\"> </a><a name=\"hc57a9af63-315d-1585-a261-0e337b289390\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource SubstanceDefinition &quot;57a9af63-315d-1585-a261-0e337b289390&quot; </p></div><p><b>manufacturer</b>: See on this page: Organization/49d2f0c0-4b28-9271-8aaf-2996a8b9739c</p><h3>Names</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Name</b></td></tr><tr><td style=\"display: none\">*</td><td>Biocurolol</td></tr></table></div>"
            },
            "manufacturer" : [
              // <meta>
                        <profile value="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/SubstanceDefinition-component-substance-pq"/>
                    </meta>
              {
                "reference" : "Organization/49d2f0c0-4b28-9271-8aaf-2996a8b9739c"
              }
            ],
            "name" : [
              // Organization/organization-dxpq-ex1
              {
                "name" : "Biocurolol"
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:49d2f0c0-4b28-9271-8aaf-2996a8b9739c",
          "resource" : {
            "resourceType" : "Organization",
            "id" : "49d2f0c0-4b28-9271-8aaf-2996a8b9739c",
            "text" : // id value="substance-manufacturer"/
            // organization-dxpq-ex1
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Organization_49d2f0c0-4b28-9271-8aaf-2996a8b9739c\"> </a><p><b>Generated Narrative: Organization</b><a name=\"49d2f0c0-4b28-9271-8aaf-2996a8b9739c\"> </a><a name=\"hc49d2f0c0-4b28-9271-8aaf-2996a8b9739c\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Organization &quot;49d2f0c0-4b28-9271-8aaf-2996a8b9739c&quot; </p></div><p><b>identifier</b>: <code>urn:oid:2.16.840.1.113883.4.82</code>/3003040516</p><p><b>active</b>: true</p><p><b>type</b>: Drug Substance Manufacture <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-organization-type.html\">Pharmaceutical Organization Type Codes</a>#drug-substance-manufacture)</span></p><p><b>name</b>: AAA Molybdenum Products, Inc.</p><h3>Contacts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Address</b></td></tr><tr><td style=\"display: none\">*</td><td>7233 W 116th Pl Ste C Broomfield Colorado 80020 USA </td></tr></table></div>"
            },
            "identifier" : [
              // <meta>
                        <profile value="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Organization-pq"/>
                    </meta>
              {
                "system" : "urn:oid:2.16.840.1.113883.4.82",
                "value" : "3003040516"
              }
            ],
            "active" : true,
            "type" : [
              //  FDA establishment identifier
              {
                "coding" : [
                  {
                    "system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-organization-type",
                    "code" : "drug-substance-manufacture",
                    "display" : "Drug Substance Manufacture"
                  }
                ]
              }
            ],
            "name" : "AAA Molybdenum Products, Inc.",
            "contact" : [
              {
                "address" : {
                  "line" : [
                    "7233 W 116th Pl",
                    "Ste C"
                  ],
                  "city" : "Broomfield",
                  "state" : "Colorado",
                  "postalCode" : "80020",
                  "country" : "USA"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:bf6b038b-1334-3dd4-a552-65c169e2265a",
          "resource" : //  another outer action can be the whole thing, if needed
          //  removed the main actions for brevity (see manufacturing example)
          {
            "resourceType" : "PlanDefinition",
            "id" : "bf6b038b-1334-3dd4-a552-65c169e2265a",
            "meta" : // manufacturingProcess-subset-unlinked
            //  indicate this is as subset of the resource. In practice it would have it all
            {
              "profile" : [
                🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/PlanDefinition-drug-pq"
              ],
              "tag" : [
                {
                  "system" : "http://terminology.hl7.org/CodeSystem/v3-ObservationValue",
                  "code" : "SUBSETTED"
                }
              ]
            },
            "text" : {
              "status" : "extensions",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"PlanDefinition_bf6b038b-1334-3dd4-a552-65c169e2265a\"> </a><p><b>Generated Narrative: PlanDefinition</b><a name=\"bf6b038b-1334-3dd4-a552-65c169e2265a\"> </a><a name=\"hcbf6b038b-1334-3dd4-a552-65c169e2265a\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource PlanDefinition &quot;bf6b038b-1334-3dd4-a552-65c169e2265a&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-PlanDefinition-drug-pq.html\">PlanDefinition - Drug PQ</a></p><p style=\"margin-bottom: 0px\">Tag: <span title=\"{http://terminology.hl7.org/CodeSystem/v3-ObservationValue http://terminology.hl7.org/CodeSystem/v3-ObservationValue}\">http://terminology.hl7.org/CodeSystem/v3-ObservationValue</span></p></div><p><b>Extension - History of Process PQ</b>: This can be text about the history</p><p><b>url</b>: <code>http://example-server.com/fhir/PlanDefinition/bf6b038b-1334-3dd4-a552-65c169e2265a</code></p><p><b>title</b>: Process 1.0</p><p><b>type</b>: Workflow Definition <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.0.0/CodeSystem-plan-definition-type.html\">PlanDefinitionType</a>#workflow-definition; <a href=\"CodeSystem-pharmaceutical-plan-type.html\">Pharmaceutical Plan Type Codes</a>#manufacturing-process &quot;Manufacturing Process&quot;)</span></p><p><b>status</b>: active</p><p><b>subject</b>: See on this page: MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5</p><p><b>description</b>: Narrative description of manufacturing process (5)</p><blockquote><p><b>goal</b></p><blockquote><p><b>id</b></p>goal-control-pH</blockquote><p><b>category</b>: Physical Property <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-test-category.html\">Pharmaceutical Test Category Codes</a>#C123456)</span></p><p><b>description</b>: Controls - pH <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>priority</b>: Critical <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-goalPriority-pq-example.html\">Goal Priority - example</a>#critical)</span></p><h3>Targets</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Measure</b></td><td><b>Detail[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>pH must be in range 6.9 to 7.1 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#pH &quot;pH&quot;)</span></td><td>6.9-7.1 pH</td></tr></table></blockquote><blockquote><p><b>goal</b></p><blockquote><p><b>id</b></p>goal-control-water-content</blockquote><p><b>category</b>: Physical Property <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-test-category.html\">Pharmaceutical Test Category Codes</a>#C123456)</span></p><p><b>description</b>: Controls - Water Content <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>priority</b>: Critical <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-goalPriority-pq-example.html\">Goal Priority - example</a>#critical)</span></p><h3>Targets</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Measure</b></td><td><b>Detail[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Under 2% <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#WaterContent &quot;Water content&quot;)</span></td><td>?-2</td></tr></table></blockquote><blockquote><p><b>goal</b></p><blockquote><p><b>id</b></p>goal-control-particle-size</blockquote><p><b>category</b>: Physical Property <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-test-category.html\">Pharmaceutical Test Category Codes</a>#C123456)</span></p><p><b>description</b>: Controls - Particle Size <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>priority</b>: Critical <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-goalPriority-pq-example.html\">Goal Priority - example</a>#critical)</span></p><h3>Targets</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Measure</b></td><td><b>Detail[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Under 200 microns <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq-example.html\">Example Local Codes - Drug</a>#particle-size &quot;Particle Size&quot;)</span></td><td>?-200</td></tr></table></blockquote><blockquote><p><b>actor</b></p><h3>Options</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>TypeReference</b></td><td><b>Role</b></td></tr><tr><td style=\"display: none\">*</td><td>See on this page: DeviceDefinition/82a39a18-91cf-a29d-76c1-a9e8bad9494d</td><td>Mixing Vessel <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-manufacturing-equipment-class.html\">Pharmaceutical Manufacturing Equipment Class Codes</a>#mixing-vessel)</span></td></tr></table></blockquote><blockquote><p><b>actor</b></p><h3>Options</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>TypeReference</b></td><td><b>Role</b></td></tr><tr><td style=\"display: none\">*</td><td>See on this page: DeviceDefinition/82a39a18-91cf-b29d-76c1-a9e8bad9494d</td><td>Receiving Vessel <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-manufacturing-equipment-class.html\">Pharmaceutical Manufacturing Equipment Class Codes</a>#receiving-vessel)</span></td></tr></table></blockquote></div>"
            },
            "extension" : [
              {
                "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-history-of-process-pq",
                "valueMarkdown" : "This can be text about the history"
              }
            ],
            "url" : "http://example-server.com/fhir/PlanDefinition/bf6b038b-1334-3dd4-a552-65c169e2265a",
            "title" : "Process 1.0",
            "type" : // http://example-server.com/fhir/PlanDefinition/bf6b038b-1334-3dd4-a552-65c169e2265a
            {
              "coding" : [
                {
                  "system" : "http://terminology.hl7.org/CodeSystem/plan-definition-type",
                  "code" : "workflow-definition",
                  "display" : "Workflow Definition"
                },
                {
                  "system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-plan-type",
                  "code" : "manufacturing-process",
                  "display" : "Manufacturing Process"
                }
              ]
            },
            "status" : "active",
            "subjectReference" : {
              "reference" : "MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"
            },
            "description" : "Narrative description of manufacturing process (5)",
            "goal" : [
              // MedicinalProductDefinition/medicinalproductdefinition-drug-product-pq-ex1
              {
                "id" : "goal-control-pH",
                "category" : {
                  "coding" : [
                    {
                      "system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-test-category",
                      "code" : "C123456",
                      "display" : "Physical Property"
                    }
                  ]
                },
                "description" : //  this is mandatory, even though we don't really want it
                {
                  "text" : "Controls - pH"
                },
                "priority" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-goalPriority-pq-example",
                      "code" : "critical",
                      "display" : "Critical"
                    }
                  ]
                },
                "target" : [
                  {
                    "measure" : {
                      "coding" : [
                        {
                          "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                          "code" : "pH",
                          "display" : "pH"
                        }
                      ],
                      "text" : "pH must be in range 6.9 to 7.1"
                    },
                    "detailRange" : // detailString value="can also be a string"
                    {
                      "low" : {
                        "value" : 6.9,
                        "unit" : "pH"
                      },
                      "high" : {
                        "value" : 7.1,
                        "unit" : "pH"
                      }
                    }
                  }
                ]
              },
              {
                "id" : "goal-control-water-content",
                "category" : {
                  "coding" : [
                    {
                      "system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-test-category",
                      "code" : "C123456",
                      "display" : "Physical Property"
                    }
                  ]
                },
                "description" : //  this is mandatory, even though we don't really want it
                {
                  "text" : "Controls - Water Content"
                },
                "priority" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-goalPriority-pq-example",
                      "code" : "critical",
                      "display" : "Critical"
                    }
                  ]
                },
                "target" : [
                  {
                    "measure" : {
                      "coding" : [
                        {
                          "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                          "code" : "WaterContent",
                          "display" : "Water content"
                        }
                      ],
                      "text" : "Under 2%"
                    },
                    "detailRange" : // detailString value="can also be a string"
                    {
                      "high" : {
                        "value" : 2,
                        "unit" : "%"
                      }
                    }
                  }
                ]
              },
              {
                "id" : "goal-control-particle-size",
                "category" : {
                  "coding" : [
                    {
                      "system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-test-category",
                      "code" : "C123456",
                      "display" : "Physical Property"
                    }
                  ]
                },
                "description" : {
                  "text" : "Controls - Particle Size"
                },
                "priority" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-goalPriority-pq-example",
                      "code" : "critical",
                      "display" : "Critical"
                    }
                  ]
                },
                "target" : [
                  {
                    "measure" : {
                      "coding" : [
                        {
                          "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq-example",
                          "code" : "particle-size",
                          "display" : "Particle Size"
                        }
                      ],
                      "text" : "Under 200 microns"
                    },
                    "detailRange" : // detailString value="can also be a string"
                    {
                      "high" : {
                        "value" : 200,
                        "unit" : "microns"
                      }
                    }
                  }
                ]
              }
            ],
            "actor" : [
              {
                "option" : [
                  {
                    "typeReference" : {
                      "reference" : "DeviceDefinition/82a39a18-91cf-a29d-76c1-a9e8bad9494d"
                    },
                    "role" : // DeviceDefinition/mixing-vessel
                    {
                      "coding" : [
                        {
                          "system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-manufacturing-equipment-class",
                          "code" : "mixing-vessel",
                          "display" : "Mixing Vessel"
                        }
                      ]
                    }
                  }
                ]
              },
              {
                "option" : [
                  {
                    "typeReference" : {
                      "reference" : "DeviceDefinition/82a39a18-91cf-b29d-76c1-a9e8bad9494d"
                    },
                    "role" : // DeviceDefinition/receiving-tank
                    {
                      "coding" : [
                        {
                          "system" : "http://terminology.hl7.org/CodeSystem/pharmaceutical-manufacturing-equipment-class",
                          "code" : "receiving-vessel",
                          "display" : "Receiving Vessel"
                        }
                      ]
                    }
                  }
                ]
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:82a39a18-91cf-a29d-76c1-a9e8bad9494d",
          "resource" : {
            "resourceType" : "DeviceDefinition",
            "id" : "82a39a18-91cf-a29d-76c1-a9e8bad9494d",
            "text" : // mixing-vessel
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"DeviceDefinition_82a39a18-91cf-a29d-76c1-a9e8bad9494d\"> </a><p><b>Generated Narrative: DeviceDefinition</b><a name=\"82a39a18-91cf-a29d-76c1-a9e8bad9494d\"> </a><a name=\"hc82a39a18-91cf-a29d-76c1-a9e8bad9494d\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource DeviceDefinition &quot;82a39a18-91cf-a29d-76c1-a9e8bad9494d&quot; </p></div><h3>DeviceNames</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Name</b></td><td><b>Type</b></td></tr><tr><td style=\"display: none\">*</td><td>Mixing Vessel</td><td>registered-name</td></tr></table><h3>Classifications</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td></tr><tr><td style=\"display: none\">*</td><td>Mixing Vessel <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-deviceType-pq-example.html\">Device Type - example</a>#mixing-vessel)</span></td></tr></table><h3>Properties</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Capacity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-device-property.html\">Device Property Codes</a>#Capacity)</span></td><td>1000 litres</td></tr></table></div>"
            },
            "deviceName" : [
              {
                "name" : "Mixing Vessel",
                "type" : "registered-name"
              }
            ],
            "classification" : [
              {
                "type" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-deviceType-pq-example",
                      "code" : "mixing-vessel",
                      "display" : "Mixing Vessel"
                    }
                  ]
                }
              }
            ],
            "property" : [
              {
                "type" : {
                  "coding" : [
                    //  seems a little different to "maximum capacity
                    {
                      "system" : "http://terminology.hl7.org/CodeSystem/device-property",
                      "code" : "Capacity",
                      "display" : "Capacity"
                    }
                  ]
                },
                "valueQuantity" : {
                  "value" : 1000,
                  "unit" : "litres"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:82a39a18-91cf-b29d-76c1-a9e8bad9494d",
          "resource" : {
            "resourceType" : "DeviceDefinition",
            "id" : "82a39a18-91cf-b29d-76c1-a9e8bad9494d",
            "text" : // receiving-tank
            {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"DeviceDefinition_82a39a18-91cf-b29d-76c1-a9e8bad9494d\"> </a><p><b>Generated Narrative: DeviceDefinition</b><a name=\"82a39a18-91cf-b29d-76c1-a9e8bad9494d\"> </a><a name=\"hc82a39a18-91cf-b29d-76c1-a9e8bad9494d\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource DeviceDefinition &quot;82a39a18-91cf-b29d-76c1-a9e8bad9494d&quot; </p></div><h3>DeviceNames</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Name</b></td><td><b>Type</b></td></tr><tr><td style=\"display: none\">*</td><td>Receiving Tank</td><td>registered-name</td></tr></table><h3>Classifications</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td></tr><tr><td style=\"display: none\">*</td><td>Receiving Tank <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-deviceType-pq-example.html\">Device Type - example</a>#receiving-tank)</span></td></tr></table><h3>Properties</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Capacity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-device-property.html\">Device Property Codes</a>#Capacity)</span></td><td>1200 litres</td></tr></table></div>"
            },
            "deviceName" : [
              {
                "name" : "Receiving Tank",
                "type" : "registered-name"
              }
            ],
            "classification" : [
              {
                "type" : {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-deviceType-pq-example",
                      "code" : "receiving-tank",
                      "display" : "Receiving Tank"
                    }
                  ]
                }
              }
            ],
            "property" : [
              {
                "type" : {
                  "coding" : [
                    //  seems a little different to "maximum capacity
                    {
                      "system" : "http://terminology.hl7.org/CodeSystem/device-property",
                      "code" : "Capacity",
                      "display" : "Capacity"
                    }
                  ]
                },
                "valueQuantity" : {
                  "value" : 1200,
                  "unit" : "litres"
                }
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:fc078762-81c5-5656-9744-13c7ad1e595b",
          "resource" : {
            "resourceType" : "Substance",
            "id" : "fc078762-81c5-5656-9744-13c7ad1e595b",
            "text" : // <id value="actual-batch-substance"/>
            // substance-dxpq-ex1
            {
              "status" : "extensions",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Substance_fc078762-81c5-5656-9744-13c7ad1e595b\"> </a><p><b>Generated Narrative: Substance</b><a name=\"fc078762-81c5-5656-9744-13c7ad1e595b\"> </a><a name=\"hcfc078762-81c5-5656-9744-13c7ad1e595b\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Substance &quot;fc078762-81c5-5656-9744-13c7ad1e595b&quot; </p></div><blockquote><p><b>Medication Manufacturing Batch</b></p><blockquote><p><b>url</b></p><code>manufacturingDate</code></blockquote><p><b>value</b>: 2019-09-07</p><blockquote><p><b>url</b></p><code>batchQuantity</code></blockquote><p><b>value</b>: 5 kg</p><blockquote><p><b>url</b></p><code>batchUtilization</code></blockquote><p><b>value</b>: Development <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.0.0/CodeSystem-v3-nciThesaurus.html\">NCI Thesaurus</a>#C133991)</span></p><blockquote><p><b>url</b></p><code>assignedManufacturer</code></blockquote><p><b>value</b>: See on this page: Organization/49d2f0c0-4b28-9271-8aaf-2996a8b9739c</p></blockquote><p><b>Extension - Batch Release Date PQ</b>: 2019-09-08</p><p><b>Extension - Batch Retest Date PQ</b>: 2022-09-08</p><p><b>Extension - Actual Yield PQ</b>: 4.8 kg</p><p><b>identifier</b>: CAT1</p><p><b>instance</b>: true</p><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td>See on this page: SubstanceDefinition/57a9af63-315d-1585-a261-0e337b289390</td></tr></table></div>"
            },
            "extension" : [
              // <meta>
                        <profile value="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Substance-pq"/>
                    </meta>
              {
                "url" : "http://hl7.org/fhir/StructureDefinition/medication-manufacturingBatch",
                "extension" : [
                  {
                    "url" : "manufacturingDate",
                    "valueDateTime" : "2019-09-07"
                  },
                  {
                    "url" : "batchQuantity",
                    "valueQuantity" : {
                      "value" : 5,
                      "unit" : "kg"
                    }
                  },
                  {
                    "url" : "batchUtilization",
                    "valueCodeableConcept" : {
                      "coding" : [
                        {
                          "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                          "code" : "C133991",
                          "display" : "Development"
                        }
                      ]
                    }
                  },
                  {
                    "url" : "assignedManufacturer",
                    "valueReference" : {
                      "reference" : "Organization/49d2f0c0-4b28-9271-8aaf-2996a8b9739c"
                    }
                  }
                ]
              },
              // Organization/organization-dxpq-ex1
              {
                "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-release-date-pq",
                "valueDateTime" : "2019-09-08"
              },
              {
                "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-retest-date-pq",
                "valueDateTime" : "2022-09-08"
              },
              {
                "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-pq",
                "valueQuantity" : {
                  "value" : 4.8,
                  "unit" : "kg"
                }
              }
            ],
            "identifier" : [
              //  local extensions
              {
                "value" : "CAT1"
              }
            ],
            "instance" : true,
            "code" : {
              "reference" : {
                "reference" : "SubstanceDefinition/57a9af63-315d-1585-a261-0e337b289390"
              }
            }
          }
        },
        // SubstanceDefinition/substancedefinition-component-substance-dxpq-ex1
        {
          "fullUrl" : "urn:uuid:cb31d747-2338-88d5-342c-8e9c097e4dad",
          "resource" : {
            "resourceType" : "Substance",
            "id" : "cb31d747-2338-88d5-342c-8e9c097e4dad",
            "text" : // actual-batch-substance-2
            {
              "status" : "extensions",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Substance_cb31d747-2338-88d5-342c-8e9c097e4dad\"> </a><p><b>Generated Narrative: Substance</b><a name=\"cb31d747-2338-88d5-342c-8e9c097e4dad\"> </a><a name=\"hccb31d747-2338-88d5-342c-8e9c097e4dad\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Substance &quot;cb31d747-2338-88d5-342c-8e9c097e4dad&quot; </p></div><blockquote><p><b>Medication Manufacturing Batch</b></p><blockquote><p><b>url</b></p><code>manufacturingDate</code></blockquote><p><b>value</b>: 2019-09-07</p><blockquote><p><b>url</b></p><code>batchQuantity</code></blockquote><p><b>value</b>: 5 kg</p><blockquote><p><b>url</b></p><code>batchUtilization</code></blockquote><p><b>value</b>: Development <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.0.0/CodeSystem-v3-nciThesaurus.html\">NCI Thesaurus</a>#C133991)</span></p><blockquote><p><b>url</b></p><code>assignedManufacturer</code></blockquote><p><b>value</b>: See on this page: Organization/49d2f0c0-4b28-9271-8aaf-2996a8b9739c</p></blockquote><p><b>Extension - Batch Release Date PQ</b>: 2019-09-08</p><p><b>Extension - Batch Retest Date PQ</b>: 2022-09-08</p><p><b>Extension - Actual Yield PQ</b>: 4.8 kg</p><p><b>identifier</b>: SUB2</p><p><b>instance</b>: true</p><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td>See on this page: SubstanceDefinition/57a9af63-315d-1585-a261-0e337b289390</td></tr></table></div>"
            },
            "extension" : [
              {
                "url" : "http://hl7.org/fhir/StructureDefinition/medication-manufacturingBatch",
                "extension" : [
                  {
                    "url" : "manufacturingDate",
                    "valueDateTime" : "2019-09-07"
                  },
                  {
                    "url" : "batchQuantity",
                    "valueQuantity" : {
                      "value" : 5,
                      "unit" : "kg"
                    }
                  },
                  {
                    "url" : "batchUtilization",
                    "valueCodeableConcept" : {
                      "coding" : [
                        {
                          "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                          "code" : "C133991",
                          "display" : "Development"
                        }
                      ]
                    }
                  },
                  {
                    "url" : "assignedManufacturer",
                    "valueReference" : {
                      "reference" : "Organization/49d2f0c0-4b28-9271-8aaf-2996a8b9739c"
                    }
                  }
                ]
              },
              // Organization/organization-dxpq-ex1
              {
                "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-release-date-pq",
                "valueDateTime" : "2019-09-08"
              },
              {
                "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-retest-date-pq",
                "valueDateTime" : "2022-09-08"
              },
              {
                "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-pq",
                "valueQuantity" : {
                  "value" : 4.8,
                  "unit" : "kg"
                }
              }
            ],
            "identifier" : [
              //  local extensions
              {
                "value" : "SUB2"
              }
            ],
            "instance" : true,
            "code" : {
              "reference" : {
                "reference" : "SubstanceDefinition/57a9af63-315d-1585-a261-0e337b289390"
              }
            }
          }
        },
        // SubstanceDefinition/substancedefinition-component-substance-dxpq-ex1
        {
          "fullUrl" : "urn:uuid:1551f97b-6f6d-825e-1fb3-44b0b090808c",
          "resource" : {
            "resourceType" : "Substance",
            "id" : "1551f97b-6f6d-825e-1fb3-44b0b090808c",
            "text" : // actual-batch-substance-3
            {
              "status" : "extensions",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Substance_1551f97b-6f6d-825e-1fb3-44b0b090808c\"> </a><p><b>Generated Narrative: Substance</b><a name=\"1551f97b-6f6d-825e-1fb3-44b0b090808c\"> </a><a name=\"hc1551f97b-6f6d-825e-1fb3-44b0b090808c\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Substance &quot;1551f97b-6f6d-825e-1fb3-44b0b090808c&quot; </p></div><blockquote><p><b>Medication Manufacturing Batch</b></p><blockquote><p><b>url</b></p><code>manufacturingDate</code></blockquote><p><b>value</b>: 2019-09-07</p><blockquote><p><b>url</b></p><code>batchQuantity</code></blockquote><p><b>value</b>: 5 kg</p><blockquote><p><b>url</b></p><code>batchUtilization</code></blockquote><p><b>value</b>: Development <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.0.0/CodeSystem-v3-nciThesaurus.html\">NCI Thesaurus</a>#C133991)</span></p><blockquote><p><b>url</b></p><code>assignedManufacturer</code></blockquote><p><b>value</b>: See on this page: Organization/49d2f0c0-4b28-9271-8aaf-2996a8b9739c</p></blockquote><p><b>Extension - Batch Release Date PQ</b>: 2019-09-08</p><p><b>Extension - Batch Retest Date PQ</b>: 2022-09-08</p><p><b>Extension - Actual Yield PQ</b>: 4.8 kg</p><p><b>identifier</b>: SUB3</p><p><b>instance</b>: true</p><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td>See on this page: SubstanceDefinition/57a9af63-315d-1585-a261-0e337b289390</td></tr></table></div>"
            },
            "extension" : [
              {
                "url" : "http://hl7.org/fhir/StructureDefinition/medication-manufacturingBatch",
                "extension" : [
                  {
                    "url" : "manufacturingDate",
                    "valueDateTime" : "2019-09-07"
                  },
                  {
                    "url" : "batchQuantity",
                    "valueQuantity" : {
                      "value" : 5,
                      "unit" : "kg"
                    }
                  },
                  {
                    "url" : "batchUtilization",
                    "valueCodeableConcept" : {
                      "coding" : [
                        {
                          "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                          "code" : "C133991",
                          "display" : "Development"
                        }
                      ]
                    }
                  },
                  {
                    "url" : "assignedManufacturer",
                    "valueReference" : {
                      "reference" : "Organization/49d2f0c0-4b28-9271-8aaf-2996a8b9739c"
                    }
                  }
                ]
              },
              // Organization/organization-dxpq-ex1
              {
                "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-release-date-pq",
                "valueDateTime" : "2019-09-08"
              },
              {
                "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-retest-date-pq",
                "valueDateTime" : "2022-09-08"
              },
              {
                "url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-pq",
                "valueQuantity" : {
                  "value" : 4.8,
                  "unit" : "kg"
                }
              }
            ],
            "identifier" : [
              //  local extensions
              {
                "value" : "SUB3"
              }
            ],
            "instance" : true,
            "code" : {
              "reference" : {
                "reference" : "SubstanceDefinition/57a9af63-315d-1585-a261-0e337b289390"
              }
            }
          }
        }
      ]
    }