Pharmaceutical Quality (Industry)
1.0.0 - STU1

Pharmaceutical Quality (Industry), published by HL7 International / Biomedical Research and Regulation. This guide is not an authorized publication; it is the continuous build for version 1.0.0 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/uv-dx-pq/ and changes regularly. See the Directory of published versions

## : Example: Bundle – Product Composition - TTL Representation

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    @prefix fhir: <http://hl7.org/fhir/> .
    @prefix owl: <http://www.w3.org/2002/07/owl#> .
    @prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
    @prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

    # - resource -------------------------------------------------------------------

     a fhir:Bundle ;
      fhir:nodeRole fhir:treeRoot ;
      fhir:id [ fhir:v "bundle-drug-product-composition-pq-ex1"] ; #
      fhir:meta [
        ( fhir:profile [
    fhir:v "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Bundle-drug-product-composition-pq"^^xsd:anyURI ;
    fhir:link <http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Bundle-drug-product-composition-pq>     ] )
      ] ; #
      fhir:type [ fhir:v "collection"] ; #
      fhir:entry ( [
    fhir:fullUrl [ fhir:v "urn:uuid:a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"^^xsd:anyURI ] ;
        ( fhir:resource <urn:uuid:a0694a7a-aafa-4cbe-8135-c788a9a4d3d5> ) #  Section 1.1 - DP Identification
      ] [
    fhir:fullUrl [ fhir:v "urn:uuid:88a068e2-1d97-337b-3b9c-4b3f14bc3923"^^xsd:anyURI ] ;
        ( fhir:resource <urn:uuid:88a068e2-1d97-337b-3b9c-4b3f14bc3923> )
      ] [
    fhir:fullUrl [ fhir:v "urn:uuid:b89ed9d2-80f9-0cfb-70a1-5a6572e73a65"^^xsd:anyURI ] ;
        ( fhir:resource <urn:uuid:b89ed9d2-80f9-0cfb-70a1-5a6572e73a65> )
      ] [
    fhir:fullUrl [ fhir:v "urn:uuid:b89ed9d3-80f9-0cfb-70a1-5a6572e73a65"^^xsd:anyURI ] ;
        ( fhir:resource <urn:uuid:b89ed9d3-80f9-0cfb-70a1-5a6572e73a65> )
      ] [
    fhir:fullUrl [ fhir:v "urn:uuid:b89ed9d2-80f9-0cfb-71a1-5a6572e73a65"^^xsd:anyURI ] ;
        ( fhir:resource <urn:uuid:b89ed9d2-80f9-0cfb-71a1-5a6572e73a65> )
      ] [
    fhir:fullUrl [ fhir:v "urn:uuid:b89ed9d2-80f9-0cfb-70a1-5a6572e73a66"^^xsd:anyURI ] ;
        ( fhir:resource <urn:uuid:b89ed9d2-80f9-0cfb-70a1-5a6572e73a66> )
      ] [
    fhir:fullUrl [ fhir:v "urn:uuid:b89ed9d3-80f9-0cfb-70a1-5a6572e73a66"^^xsd:anyURI ] ;
        ( fhir:resource <urn:uuid:b89ed9d3-80f9-0cfb-70a1-5a6572e73a66> )
      ] [
    fhir:fullUrl [ fhir:v "urn:uuid:4cf2cbba-33e6-1124-9bf2-1c6756380474"^^xsd:anyURI ] ;
        ( fhir:resource <urn:uuid:4cf2cbba-33e6-1124-9bf2-1c6756380474> )
      ] [
    fhir:fullUrl [ fhir:v "urn:uuid:4cf2cbba-33e6-1124-9bf2-1c6756380475"^^xsd:anyURI ] ;
        ( fhir:resource <urn:uuid:4cf2cbba-33e6-1124-9bf2-1c6756380475> )
      ] [
    fhir:fullUrl [ fhir:v "urn:uuid:4cf2cbba-33e6-1124-9bf2-1c6756380476"^^xsd:anyURI ] ;
        ( fhir:resource <urn:uuid:4cf2cbba-33e6-1124-9bf2-1c6756380476> )
      ] [
    fhir:fullUrl [ fhir:v "urn:uuid:4cf2cbba-33e6-1124-9bf2-1c6756380477"^^xsd:anyURI ] ;
        ( fhir:resource <urn:uuid:4cf2cbba-33e6-1124-9bf2-1c6756380477> )
      ] [
    fhir:fullUrl [ fhir:v "urn:uuid:4cf2cbba-33e6-1124-9bf2-1c6756380478"^^xsd:anyURI ] ;
        ( fhir:resource <urn:uuid:4cf2cbba-33e6-1124-9bf2-1c6756380478> )
      ] ) . #  MedicinalProductDefinition - the main resource in any product scenario

    <urn:uuid:a0694a7a-aafa-4cbe-8135-c788a9a4d3d5> a fhir:MedicinalProductDefinition ;
      fhir:id [ fhir:v "a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"] ; # medicinalproductdefinition-drug-product-dxpq-ex1
      fhir:text [
    fhir:status [ fhir:v "generated" ] ;
    fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"MedicinalProductDefinition_a0694a7a-aafa-4cbe-8135-c788a9a4d3d5\"> </a><p><b>Generated Narrative: MedicinalProductDefinition</b><a name=\"a0694a7a-aafa-4cbe-8135-c788a9a4d3d5\"> </a><a name=\"hca0694a7a-aafa-4cbe-8135-c788a9a4d3d5\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource MedicinalProductDefinition &quot;a0694a7a-aafa-4cbe-8135-c788a9a4d3d5&quot; </p></div><p><b>description</b>: Stelbatalol is formulated as an immediate-release, oral, solid dosage form in strengths of 20 mg of the free base equivalent. The 20 mg strength is presented as an orange, round, film coated tablet, debossed with '175' on one side.</p><h3>Names</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>ProductName</b></td><td><b>Type</b></td></tr><tr><td style=\"display: none\">*</td><td>Stalbatolol</td><td>Proprietary <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-productNameType-pq-example.html\">Product Name Type - example</a>#Proprietary)</span></td></tr></table></div>"
      ] ; #
      fhir:description [ fhir:v "Stelbatalol is formulated as an immediate-release, oral, solid dosage form in strengths of 20 mg of the free base equivalent. The 20 mg strength is presented as an orange, round, film coated tablet, debossed with '175' on one side."] ; #
      fhir:name ( [
    fhir:productName [ fhir:v "Stalbatolol" ] ;
    fhir:type [
          ( fhir:coding [
    fhir:system [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-productNameType-pq-example"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "Proprietary" ] ;
    fhir:display [ fhir:v "Proprietary" ]       ] )     ]
      ] ) . #

    <urn:uuid:88a068e2-1d97-337b-3b9c-4b3f14bc3923> a fhir:PackagedProductDefinition ;
      fhir:id [ fhir:v "88a068e2-1d97-337b-3b9c-4b3f14bc3923"] ; # packagedproductdefinition-dxpq-ex1
      fhir:meta [
        ( fhir:profile [
    fhir:v "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/PackagedProductDefinition-drug-pq"^^xsd:anyURI ;
    fhir:link <http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/PackagedProductDefinition-drug-pq>     ] )
      ] ; #
      fhir:text [
    fhir:status [ fhir:v "generated" ] ;
    fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"PackagedProductDefinition_88a068e2-1d97-337b-3b9c-4b3f14bc3923\"> </a><p><b>Generated Narrative: PackagedProductDefinition</b><a name=\"88a068e2-1d97-337b-3b9c-4b3f14bc3923\"> </a><a name=\"hc88a068e2-1d97-337b-3b9c-4b3f14bc3923\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource PackagedProductDefinition &quot;88a068e2-1d97-337b-3b9c-4b3f14bc3923&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-PackagedProductDefinition-drug-pq.html\">PackagedProductDefinition - Drug PQ</a></p></div><p><b>packageFor</b>: See on this page: MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5</p><p><b>description</b>: The commercial primary pack is a high-density polyethylene (HDPE) bottle with a child-resistant polypropylene (PP) screw cap.  Inside the bottle is a desiccant, containing silica gel. Induction seal membranes provide additional tamper evidence. For further details of the packaging components, see ‘P.7 Container Closure System for Drug Product’.</p></div>"
      ] ; #
      fhir:packageFor ( [
    fhir:reference [ fhir:v "MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5" ] # MedicinalProductDefinition\/medicinalproductdefinition-drug-product-dxpq-ex1
      ] ) ; #
      fhir:description [ fhir:v "The commercial primary pack is a high-density polyethylene (HDPE) bottle with a child-resistant polypropylene (PP) screw cap.  Inside the bottle is a desiccant, containing silica gel. Induction seal membranes provide additional tamper evidence. For further details of the packaging components, see ‘P.7 Container Closure System for Drug Product’."] . #

    <urn:uuid:b89ed9d2-80f9-0cfb-70a1-5a6572e73a65> a fhir:Ingredient ;
      fhir:id [ fhir:v "b89ed9d2-80f9-0cfb-70a1-5a6572e73a65"] ; # ingredient1
      fhir:text [
    fhir:status [ fhir:v "generated" ] ;
    fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Ingredient_b89ed9d2-80f9-0cfb-70a1-5a6572e73a65\"> </a><p><b>Generated Narrative: Ingredient</b><a name=\"b89ed9d2-80f9-0cfb-70a1-5a6572e73a65\"> </a><a name=\"hcb89ed9d2-80f9-0cfb-70a1-5a6572e73a65\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Ingredient &quot;b89ed9d2-80f9-0cfb-70a1-5a6572e73a65&quot; </p></div><p><b>status</b>: active</p><p><b>for</b>: See on this page: MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5</p><p><b>role</b>: Active <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-ingredient-role.html\">Ingredient Role</a>#100000072072)</span></p><blockquote><p><b>substance</b></p><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td>See on this page: SubstanceDefinition/4cf2cbba-33e6-1124-9bf2-1c6756380474: Stelbatolol</td></tr></table><blockquote><p><b>strength</b></p><p><b>presentation</b>: 15.2 mg/1 tablet</p></blockquote><blockquote><p><b>strength</b></p><p><b>concentration</b>: 97.9 % w/w</p></blockquote></blockquote></div>"
      ] ; #
      fhir:status [ fhir:v "active"] ; #
      fhir:for ( [
    fhir:reference [ fhir:v "MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5" ] # MedicinalProductDefinition\/medicinalproductdefinition-drug-product-dxpq-ex1
      ] ) ; #
      fhir:role [
        ( fhir:coding [
    fhir:system [ fhir:v "http://hl7.org/fhir/ingredient-role"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "100000072072" ] ;
    fhir:display [ fhir:v "Active" ]     ] )
      ] ; #
      fhir:substance [
    fhir:code [
    fhir:reference [
    fhir:reference [ fhir:v "SubstanceDefinition/4cf2cbba-33e6-1124-9bf2-1c6756380474" ] ; # SubstanceDefinition\/substance1
    fhir:display [ fhir:v "Stelbatolol" ]       ]     ] ;
        ( fhir:strength [
    fhir:presentation [
    a fhir:Ratio ;
    fhir:numerator [
    fhir:value [ fhir:v "15.2"^^xsd:decimal ] ;
    fhir:unit [ fhir:v "mg" ]         ] ; #  todo add ucum
    fhir:denominator [
    fhir:value [ fhir:v "1"^^xsd:decimal ] ;
    fhir:unit [ fhir:v "tablet" ]         ]       ]     ] [
    fhir:concentration [
    a fhir:Quantity ;
    fhir:value [ fhir:v "97.9"^^xsd:decimal ] ;
    fhir:unit [ fhir:v "% w/w" ]       ]     ] )
      ] . #

    <urn:uuid:b89ed9d3-80f9-0cfb-70a1-5a6572e73a65> a fhir:Ingredient ;
      fhir:id [ fhir:v "b89ed9d3-80f9-0cfb-70a1-5a6572e73a65"] ; # excipient1
      fhir:text [
    fhir:status [ fhir:v "generated" ] ;
    fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Ingredient_b89ed9d3-80f9-0cfb-70a1-5a6572e73a65\"> </a><p><b>Generated Narrative: Ingredient</b><a name=\"b89ed9d3-80f9-0cfb-70a1-5a6572e73a65\"> </a><a name=\"hcb89ed9d3-80f9-0cfb-70a1-5a6572e73a65\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Ingredient &quot;b89ed9d3-80f9-0cfb-70a1-5a6572e73a65&quot; </p></div><p><b>status</b>: active</p><p><b>for</b>: See on this page: MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5</p><p><b>role</b>: Excipient <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-ingredient-role.html\">Ingredient Role</a>#100000072082)</span></p><p><b>function</b>: Diluent <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-ingredient-function.html\">Ingredient Function Codes</a>#diluent)</span></p><blockquote><p><b>substance</b></p><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td>See on this page: SubstanceDefinition/4cf2cbba-33e6-1124-9bf2-1c6756380475: Mannitol</td></tr></table><blockquote><p><b>strength</b></p><p><b>presentation</b>: 145.0 mg/1 tablet</p></blockquote><blockquote><p><b>strength</b></p><p><b>concentration</b>: 1 % w/w</p></blockquote></blockquote></div>"
      ] ; #
      fhir:status [ fhir:v "active"] ; #
      fhir:for ( [
    fhir:reference [ fhir:v "MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5" ] # MedicinalProductDefinition\/medicinalproductdefinition-drug-product-dxpq-ex1
      ] ) ; #
      fhir:role [
        ( fhir:coding [
    fhir:system [ fhir:v "http://hl7.org/fhir/ingredient-role"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "100000072082" ] ;
    fhir:display [ fhir:v "Excipient" ]     ] )
      ] ; #
      fhir:function ( [
        ( fhir:coding [
    fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/ingredient-function"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "diluent" ] ;
    fhir:display [ fhir:v "Diluent" ]     ] )
      ] ) ; #
      fhir:substance [
    fhir:code [
    fhir:reference [
    fhir:reference [ fhir:v "SubstanceDefinition/4cf2cbba-33e6-1124-9bf2-1c6756380475" ] ; # SubstanceDefinition\/sd-excipient1
    fhir:display [ fhir:v "Mannitol" ]       ]     ] ;
        ( fhir:strength [
    fhir:presentation [
    a fhir:Ratio ;
    fhir:numerator [
    fhir:value [ fhir:v "145.0"^^xsd:decimal ] ;
    fhir:unit [ fhir:v "mg" ]         ] ;
    fhir:denominator [
    fhir:value [ fhir:v "1"^^xsd:decimal ] ;
    fhir:unit [ fhir:v "tablet" ]         ]       ]     ] [
    fhir:concentration [
    a fhir:Quantity ;
    fhir:value [ fhir:v "1"^^xsd:decimal ] ;
    fhir:unit [ fhir:v "% w/w" ]       ]     ] )
      ] . #

    <urn:uuid:b89ed9d2-80f9-0cfb-71a1-5a6572e73a65> a fhir:Ingredient ;
      fhir:id [ fhir:v "b89ed9d2-80f9-0cfb-71a1-5a6572e73a65"] ; # excipient2
      fhir:text [
    fhir:status [ fhir:v "generated" ] ;
    fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Ingredient_b89ed9d2-80f9-0cfb-71a1-5a6572e73a65\"> </a><p><b>Generated Narrative: Ingredient</b><a name=\"b89ed9d2-80f9-0cfb-71a1-5a6572e73a65\"> </a><a name=\"hcb89ed9d2-80f9-0cfb-71a1-5a6572e73a65\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Ingredient &quot;b89ed9d2-80f9-0cfb-71a1-5a6572e73a65&quot; </p></div><p><b>status</b>: active</p><p><b>for</b>: See on this page: MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5</p><p><b>role</b>: Excipient <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-ingredient-role.html\">Ingredient Role</a>#100000072082)</span></p><p><b>function</b>: Disintegrant <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-ingredient-function.html\">Ingredient Function Codes</a>#disintegrant)</span></p><blockquote><p><b>substance</b></p><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td>See on this page: SubstanceDefinition/4cf2cbba-33e6-1124-9bf2-1c6756380476: Maize starch</td></tr></table><blockquote><p><b>strength</b></p><p><b>presentation</b>: 13.8 mg/1 tablet</p></blockquote><blockquote><p><b>strength</b></p><p><b>concentration</b>: 0.5 % w/w</p></blockquote></blockquote></div>"
      ] ; #
      fhir:status [ fhir:v "active"] ; #
      fhir:for ( [
    fhir:reference [ fhir:v "MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5" ] # MedicinalProductDefinition\/medicinalproductdefinition-drug-product-dxpq-ex1
      ] ) ; #
      fhir:role [
        ( fhir:coding [
    fhir:system [ fhir:v "http://hl7.org/fhir/ingredient-role"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "100000072082" ] ;
    fhir:display [ fhir:v "Excipient" ]     ] )
      ] ; #
      fhir:function ( [
        ( fhir:coding [
    fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/ingredient-function"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "disintegrant" ] ;
    fhir:display [ fhir:v "Disintegrant" ]     ] )
      ] ) ; #
      fhir:substance [
    fhir:code [
    fhir:reference [
    fhir:reference [ fhir:v "SubstanceDefinition/4cf2cbba-33e6-1124-9bf2-1c6756380476" ] ; # SubstanceDefinition\/sd-excipient2
    fhir:display [ fhir:v "Maize starch" ]       ]     ] ;
        ( fhir:strength [
    fhir:presentation [
    a fhir:Ratio ;
    fhir:numerator [
    fhir:value [ fhir:v "13.8"^^xsd:decimal ] ;
    fhir:unit [ fhir:v "mg" ]         ] ;
    fhir:denominator [
    fhir:value [ fhir:v "1"^^xsd:decimal ] ;
    fhir:unit [ fhir:v "tablet" ]         ]       ]     ] [
    fhir:concentration [
    a fhir:Quantity ;
    fhir:value [ fhir:v "0.5"^^xsd:decimal ] ;
    fhir:unit [ fhir:v "% w/w" ]       ]     ] )
      ] . #

    <urn:uuid:b89ed9d2-80f9-0cfb-70a1-5a6572e73a66> a fhir:Ingredient ;
      fhir:id [ fhir:v "b89ed9d2-80f9-0cfb-70a1-5a6572e73a66"] ; # excipient3
      fhir:text [
    fhir:status [ fhir:v "generated" ] ;
    fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Ingredient_b89ed9d2-80f9-0cfb-70a1-5a6572e73a66\"> </a><p><b>Generated Narrative: Ingredient</b><a name=\"b89ed9d2-80f9-0cfb-70a1-5a6572e73a66\"> </a><a name=\"hcb89ed9d2-80f9-0cfb-70a1-5a6572e73a66\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Ingredient &quot;b89ed9d2-80f9-0cfb-70a1-5a6572e73a66&quot; </p></div><p><b>status</b>: active</p><p><b>for</b>: See on this page: MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5</p><p><b>role</b>: Excipient <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-ingredient-role.html\">Ingredient Role</a>#100000072082)</span></p><p><b>function</b>: Disintegrant <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-ingredient-function.html\">Ingredient Function Codes</a>#disintegrant)</span></p><blockquote><p><b>substance</b></p><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td>See on this page: SubstanceDefinition/4cf2cbba-33e6-1124-9bf2-1c6756380477: Calcium carboxymethylcellulose</td></tr></table><blockquote><p><b>strength</b></p><p><b>presentation</b>: 4.0 mg/1 tablet</p></blockquote><blockquote><p><b>strength</b></p><p><b>concentration</b>: 0.25 % w/w</p></blockquote></blockquote></div>"
      ] ; #
      fhir:status [ fhir:v "active"] ; #
      fhir:for ( [
    fhir:reference [ fhir:v "MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5" ] # MedicinalProductDefinition\/medicinalproductdefinition-drug-product-dxpq-ex1
      ] ) ; #
      fhir:role [
        ( fhir:coding [
    fhir:system [ fhir:v "http://hl7.org/fhir/ingredient-role"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "100000072082" ] ;
    fhir:display [ fhir:v "Excipient" ]     ] )
      ] ; #
      fhir:function ( [
        ( fhir:coding [
    fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/ingredient-function"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "disintegrant" ] ;
    fhir:display [ fhir:v "Disintegrant" ]     ] )
      ] ) ; #
      fhir:substance [
    fhir:code [
    fhir:reference [
    fhir:reference [ fhir:v "SubstanceDefinition/4cf2cbba-33e6-1124-9bf2-1c6756380477" ] ; # SubstanceDefinition\/sd-excipient3
    fhir:display [ fhir:v "Calcium carboxymethylcellulose" ]       ]     ] ;
        ( fhir:strength [
    fhir:presentation [
    a fhir:Ratio ;
    fhir:numerator [
    fhir:value [ fhir:v "4.0"^^xsd:decimal ] ;
    fhir:unit [ fhir:v "mg" ]         ] ;
    fhir:denominator [
    fhir:value [ fhir:v "1"^^xsd:decimal ] ;
    fhir:unit [ fhir:v "tablet" ]         ]       ]     ] [
    fhir:concentration [
    a fhir:Quantity ;
    fhir:value [ fhir:v "0.25"^^xsd:decimal ] ;
    fhir:unit [ fhir:v "% w/w" ]       ]     ] )
      ] . #

    <urn:uuid:b89ed9d3-80f9-0cfb-70a1-5a6572e73a66> a fhir:Ingredient ;
      fhir:id [ fhir:v "b89ed9d3-80f9-0cfb-70a1-5a6572e73a66"] ; # excipient4
      fhir:text [
    fhir:status [ fhir:v "generated" ] ;
    fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Ingredient_b89ed9d3-80f9-0cfb-70a1-5a6572e73a66\"> </a><p><b>Generated Narrative: Ingredient</b><a name=\"b89ed9d3-80f9-0cfb-70a1-5a6572e73a66\"> </a><a name=\"hcb89ed9d3-80f9-0cfb-70a1-5a6572e73a66\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Ingredient &quot;b89ed9d3-80f9-0cfb-70a1-5a6572e73a66&quot; </p></div><p><b>status</b>: active</p><p><b>for</b>: See on this page: MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5</p><p><b>role</b>: Excipient <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-ingredient-role.html\">Ingredient Role</a>#100000072082)</span></p><p><b>function</b>: Lubricant <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-ingredient-function.html\">Ingredient Function Codes</a>#lubricant)</span></p><blockquote><p><b>substance</b></p><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td>See on this page: SubstanceDefinition/4cf2cbba-33e6-1124-9bf2-1c6756380478: Magnesium stearate</td></tr></table><blockquote><p><b>strength</b></p><p><b>presentation</b>: 2.0 mg/1 tablet</p></blockquote><blockquote><p><b>strength</b></p><p><b>concentration</b>: 0.35 % w/w</p></blockquote></blockquote></div>"
      ] ; #
      fhir:status [ fhir:v "active"] ; #
      fhir:for ( [
    fhir:reference [ fhir:v "MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5" ] # MedicinalProductDefinition\/medicinalproductdefinition-drug-product-dxpq-ex1
      ] ) ; #
      fhir:role [
        ( fhir:coding [
    fhir:system [ fhir:v "http://hl7.org/fhir/ingredient-role"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "100000072082" ] ;
    fhir:display [ fhir:v "Excipient" ]     ] )
      ] ; #
      fhir:function ( [
        ( fhir:coding [
    fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/ingredient-function"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "lubricant" ] ;
    fhir:display [ fhir:v "Lubricant" ]     ] )
      ] ) ; #
      fhir:substance [
    fhir:code [
    fhir:reference [
    fhir:reference [ fhir:v "SubstanceDefinition/4cf2cbba-33e6-1124-9bf2-1c6756380478" ] ; # SubstanceDefinition\/sd-excipient4
    fhir:display [ fhir:v "Magnesium stearate" ]       ]     ] ;
        ( fhir:strength [
    fhir:presentation [
    a fhir:Ratio ;
    fhir:numerator [
    fhir:value [ fhir:v "2.0"^^xsd:decimal ] ;
    fhir:unit [ fhir:v "mg" ]         ] ;
    fhir:denominator [
    fhir:value [ fhir:v "1"^^xsd:decimal ] ;
    fhir:unit [ fhir:v "tablet" ]         ]       ]     ] [
    fhir:concentration [
    a fhir:Quantity ;
    fhir:value [ fhir:v "0.35"^^xsd:decimal ] ;
    fhir:unit [ fhir:v "% w/w" ]       ]     ] )
      ] . #

    <urn:uuid:4cf2cbba-33e6-1124-9bf2-1c6756380474> a fhir:SubstanceDefinition ;
      fhir:id [ fhir:v "4cf2cbba-33e6-1124-9bf2-1c6756380474"] ; # substance1
      fhir:text [
    fhir:status [ fhir:v "generated" ] ;
    fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"SubstanceDefinition_4cf2cbba-33e6-1124-9bf2-1c6756380474\"> </a><p><b>Generated Narrative: SubstanceDefinition</b><a name=\"4cf2cbba-33e6-1124-9bf2-1c6756380474\"> </a><a name=\"hc4cf2cbba-33e6-1124-9bf2-1c6756380474\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource SubstanceDefinition &quot;4cf2cbba-33e6-1124-9bf2-1c6756380474&quot; </p></div><p><b>grade</b>: In-house <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-package-grade.html\">Package Grade Codes</a>#in-house)</span></p><h3>Names</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Name</b></td></tr><tr><td style=\"display: none\">*</td><td>Stelbatolol</td></tr></table></div>"
      ] ; #
      fhir:grade ( [
        ( fhir:coding [
    fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/package-grade"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "in-house" ] ;
    fhir:display [ fhir:v "In-house" ]     ] )
      ] ) ; #
      fhir:name ( [
    fhir:name [ fhir:v "Stelbatolol" ]
      ] ) . #

    <urn:uuid:4cf2cbba-33e6-1124-9bf2-1c6756380475> a fhir:SubstanceDefinition ;
      fhir:id [ fhir:v "4cf2cbba-33e6-1124-9bf2-1c6756380475"] ; # sd-excipient1
      fhir:text [
    fhir:status [ fhir:v "generated" ] ;
    fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"SubstanceDefinition_4cf2cbba-33e6-1124-9bf2-1c6756380475\"> </a><p><b>Generated Narrative: SubstanceDefinition</b><a name=\"4cf2cbba-33e6-1124-9bf2-1c6756380475\"> </a><a name=\"hc4cf2cbba-33e6-1124-9bf2-1c6756380475\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource SubstanceDefinition &quot;4cf2cbba-33e6-1124-9bf2-1c6756380475&quot; </p></div><p><b>grade</b>: NF / Ph Eur <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-package-grade.html\">Package Grade Codes</a>#NF-PH-Eur)</span></p><h3>Names</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Name</b></td></tr><tr><td style=\"display: none\">*</td><td>Mannitol</td></tr></table></div>"
      ] ; #
      fhir:grade ( [
        ( fhir:coding [
    fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/package-grade"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "NF-PH-Eur" ] ;
    fhir:display [ fhir:v "NF / Ph Eur" ]     ] )
      ] ) ; #
      fhir:name ( [
    fhir:name [ fhir:v "Mannitol" ]
      ] ) . #

    <urn:uuid:4cf2cbba-33e6-1124-9bf2-1c6756380476> a fhir:SubstanceDefinition ;
      fhir:id [ fhir:v "4cf2cbba-33e6-1124-9bf2-1c6756380476"] ; # sd-excipient2
      fhir:text [
    fhir:status [ fhir:v "generated" ] ;
    fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"SubstanceDefinition_4cf2cbba-33e6-1124-9bf2-1c6756380476\"> </a><p><b>Generated Narrative: SubstanceDefinition</b><a name=\"4cf2cbba-33e6-1124-9bf2-1c6756380476\"> </a><a name=\"hc4cf2cbba-33e6-1124-9bf2-1c6756380476\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource SubstanceDefinition &quot;4cf2cbba-33e6-1124-9bf2-1c6756380476&quot; </p></div><p><b>grade</b>: NF / Ph Eur <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-package-grade.html\">Package Grade Codes</a>#NF-PH-Eur)</span></p><h3>Names</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Name</b></td></tr><tr><td style=\"display: none\">*</td><td>Maize starch</td></tr></table></div>"
      ] ; #
      fhir:grade ( [
        ( fhir:coding [
    fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/package-grade"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "NF-PH-Eur" ] ;
    fhir:display [ fhir:v "NF / Ph Eur" ]     ] )
      ] ) ; #
      fhir:name ( [
    fhir:name [ fhir:v "Maize starch" ]
      ] ) . #

    <urn:uuid:4cf2cbba-33e6-1124-9bf2-1c6756380477> a fhir:SubstanceDefinition ;
      fhir:id [ fhir:v "4cf2cbba-33e6-1124-9bf2-1c6756380477"] ; # sd-excipient3
      fhir:text [
    fhir:status [ fhir:v "generated" ] ;
    fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"SubstanceDefinition_4cf2cbba-33e6-1124-9bf2-1c6756380477\"> </a><p><b>Generated Narrative: SubstanceDefinition</b><a name=\"4cf2cbba-33e6-1124-9bf2-1c6756380477\"> </a><a name=\"hc4cf2cbba-33e6-1124-9bf2-1c6756380477\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource SubstanceDefinition &quot;4cf2cbba-33e6-1124-9bf2-1c6756380477&quot; </p></div><p><b>grade</b>: NF / Ph Eur <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-package-grade.html\">Package Grade Codes</a>#NF-PH-Eur)</span></p><h3>Names</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Name</b></td></tr><tr><td style=\"display: none\">*</td><td>Calcium carboxymethylcellulose</td></tr></table></div>"
      ] ; #
      fhir:grade ( [
        ( fhir:coding [
    fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/package-grade"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "NF-PH-Eur" ] ;
    fhir:display [ fhir:v "NF / Ph Eur" ]     ] )
      ] ) ; #
      fhir:name ( [
    fhir:name [ fhir:v "Calcium carboxymethylcellulose" ]
      ] ) . #

    <urn:uuid:4cf2cbba-33e6-1124-9bf2-1c6756380478> a fhir:SubstanceDefinition ;
      fhir:id [ fhir:v "4cf2cbba-33e6-1124-9bf2-1c6756380478"] ; # sd-excipient4
      fhir:text [
    fhir:status [ fhir:v "generated" ] ;
    fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"SubstanceDefinition_4cf2cbba-33e6-1124-9bf2-1c6756380478\"> </a><p><b>Generated Narrative: SubstanceDefinition</b><a name=\"4cf2cbba-33e6-1124-9bf2-1c6756380478\"> </a><a name=\"hc4cf2cbba-33e6-1124-9bf2-1c6756380478\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource SubstanceDefinition &quot;4cf2cbba-33e6-1124-9bf2-1c6756380478&quot; </p></div><p><b>grade</b>: NF / Ph Eur <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-package-grade.html\">Package Grade Codes</a>#NF-PH-Eur)</span></p><h3>Names</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Name</b></td></tr><tr><td style=\"display: none\">*</td><td>Magnesium stearate</td></tr></table></div>"
      ] ; #
      fhir:grade ( [
        ( fhir:coding [
    fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/package-grade"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "NF-PH-Eur" ] ;
    fhir:display [ fhir:v "NF / Ph Eur" ]     ] )
      ] ) ; #
      fhir:name ( [
    fhir:name [ fhir:v "Magnesium stearate" ]
      ] ) . #