## Union of http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/SubstanceDefinition-component-substance-drug-pq and http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/SubstanceDefinition-component-substance-drug-pq

This is the set of resources that conform to either of the profiles SubstanceDefinition - Component Substance Drug PQ (http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/SubstanceDefinition-component-substance-drug-pq) and SubstanceDefinition - Component Substance Drug PQ (http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/SubstanceDefinition-component-substance-drug-pq). E.g. what you have to deal with if you get resources conforming to one of them

### Structure

Name | Flags | Card. | Type | Description & Constraints
--- | --- | --- | --- | ---
SubstanceDefinition |  | 0..* |  | The detailed description of a substance, typically at a level beyond what is used for prescribing dom-2: If the resource is contained in another resource, it SHALL NOT contain nested Resources dom-3: If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource dom-4: If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated dom-5: If a resource is contained in another resource, it SHALL NOT have a security label dom-6: A resource should have narrative for robust management
meta | Σ | 0..1 | Meta | Metadata about the resource ele-1: All FHIR elements must have a @value or children
implicitRules | ?!Σ | 0..1 | uri | A set of rules under which this content was created ele-1: All FHIR elements must have a @value or children
language |  | 0..1 | code | Language of the resource content Binding: ?? (required): IETF language tag for a human language ele-1: All FHIR elements must have a @value or children
text |  | 0..1 | Narrative | Text summary of the resource, for human interpretation ele-1: All FHIR elements must have a @value or children
contained |  | 0..* | Resource | Contained, inline Resources
extension |  | 0..* | Extension | Additional content defined by implementations ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
modifierExtension | ?!Σ | 0..* | Extension | Extensions that cannot be ignored ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
identifier | Σ | 0..* | Identifier | Identifier by which this substance is known ele-1: All FHIR elements must have a @value or children
version | Σ | 0..1 | string | A business level version identifier of the substance ele-1: All FHIR elements must have a @value or children
status | Σ | 0..1 | CodeableConcept | Status of substance within the catalogue e.g. active, retired Binding: ?? (preferred): The lifecycle status of an artifact. ele-1: All FHIR elements must have a @value or children
classification | Σ | 0..* | CodeableConcept | A categorization, high level e.g. polymer or nucleic acid, or food, chemical, biological, or lower e.g. polymer linear or branch chain, or type of impurity ele-1: All FHIR elements must have a @value or children
domain | Σ | 0..1 | CodeableConcept | If the substance applies to human or veterinary use Binding: ?? (example): Applicable domain for this product (e.g. human, veterinary). ele-1: All FHIR elements must have a @value or children
grade | S Σ | 0..* | CodeableConcept | The quality standard, established benchmark, to which substance complies (e.g. USP/NF, BP) Binding: ?? (example): The quality standard, established benchmark, to which a substance complies ele-1: All FHIR elements must have a @value or children
description | Σ | 0..1 | markdown | Textual description of the substance ele-1: All FHIR elements must have a @value or children
informationSource | S Σ | 0..* | Reference(Citation) | Supporting literature ele-1: All FHIR elements must have a @value or children
note | Σ | 0..* | Annotation | Textual comment about the substance's catalogue or registry record ele-1: All FHIR elements must have a @value or children
manufacturer | S Σ | 0..* | Reference(Organization - Drug PQ | #sd-Organization-drug-pq-Organization-drug-pq) | The entity that creates, makes, produces or fabricates the substance ele-1: All FHIR elements must have a @value or children
extension |  | 0..* | Extension | Extension Slice: Unordered, Open by value:url ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
reference | Σ C | 0..1 | string | Literal reference, Relative, internal or absolute URL ele-1: All FHIR elements must have a @value or children
type | Σ | 0..1 | uri | Type the reference refers to (e.g. "Patient") - must be a resource in resources Binding: ?? (extensible): Aa resource (or, for logical models, the URI of the logical model). ele-1: All FHIR elements must have a @value or children
identifier | Σ C | 0..1 | Identifier | Logical reference, when literal reference is not known ele-1: All FHIR elements must have a @value or children
display | Σ C | 0..1 | string | Text alternative for the resource ele-1: All FHIR elements must have a @value or children
supplier | Σ | 0..* | Reference(Organization) | An entity that is the source for the substance. It may be different from the manufacturer ele-1: All FHIR elements must have a @value or children
moiety | Σ | 0..* | BackboneElement | Moiety, for structural modifications ele-1: All FHIR elements must have a @value or children
extension |  | 0..* | Extension | Additional content defined by implementations ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
modifierExtension | ?!Σ | 0..* | Extension | Extensions that cannot be ignored even if unrecognized ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
role | Σ | 0..1 | CodeableConcept | Role that the moiety is playing ele-1: All FHIR elements must have a @value or children
identifier | Σ | 0..1 | Identifier | Identifier by which this moiety substance is known ele-1: All FHIR elements must have a @value or children
name | Σ | 0..1 | string | Textual name for this moiety substance ele-1: All FHIR elements must have a @value or children
stereochemistry | Σ | 0..1 | CodeableConcept | Stereochemistry type Binding: ?? (example): The optical rotation type of a substance. ele-1: All FHIR elements must have a @value or children
opticalActivity | Σ | 0..1 | CodeableConcept | Optical activity type Binding: ?? (example): The optical rotation type of a substance. ele-1: All FHIR elements must have a @value or children
molecularFormula | Σ | 0..1 | string | Molecular formula for this moiety (e.g. with the Hill system) ele-1: All FHIR elements must have a @value or children
amount[x] | Σ | 0..1 |  | Quantitative value for this moiety ele-1: All FHIR elements must have a @value or children
amountQuantity |  |  | Quantity |
amountString |  |  | string |
measurementType | Σ | 0..1 | CodeableConcept | The measurement type of the quantitative value Binding: ?? (example): The relationship between two substance types. ele-1: All FHIR elements must have a @value or children
characterization | Σ | 0..* | BackboneElement | General specifications for this substance ele-1: All FHIR elements must have a @value or children
extension |  | 0..* | Extension | Additional content defined by implementations ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
modifierExtension | ?!Σ | 0..* | Extension | Extensions that cannot be ignored even if unrecognized ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
technique | Σ | 0..1 | CodeableConcept | The method used to find the characterization e.g. HPLC Binding: ?? (example): The method used to elucidate the characterization of the drug substance. ele-1: All FHIR elements must have a @value or children
form | Σ | 0..1 | CodeableConcept | Describes the nature of the chemical entity and explains, for instance, whether this is a base or a salt form Binding: ?? (example) ele-1: All FHIR elements must have a @value or children
description | Σ | 0..1 | markdown | The description or justification in support of the interpretation of the data file ele-1: All FHIR elements must have a @value or children
file | Σ | 0..* | Attachment | The data produced by the analytical instrument or a pictorial representation of that data. Examples: a JCAMP, JDX, or ADX file, or a chromatogram or spectrum analysis ele-1: All FHIR elements must have a @value or children
property | S Σ | 0..* | BackboneElement | General specifications for this substance ele-1: All FHIR elements must have a @value or children
extension |  | 0..* | Extension | left: Additional content defined by implementations; right: Extension ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
modifierExtension | ?!Σ | 0..* | Extension | Extensions that cannot be ignored even if unrecognized ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
type | S Σ | 1..1 | CodeableConcept | A code expressing the type of property Binding: ?? (example): This value set includes all observable entity codes from SNOMED CT - provided as an exemplar value set. ele-1: All FHIR elements must have a @value or children
value[x] | S Σ | 0..1 |  | A value for the property Binding: ?? (example) ele-1: All FHIR elements must have a @value or children
valueCodeableConcept |  |  | CodeableConcept |
valueQuantity |  |  | Quantity |
valueDate |  |  | date |
valueBoolean |  |  | boolean |
valueAttachment |  |  | Attachment |
referenceInformation | Σ | 0..1 | Reference(SubstanceReferenceInformation) | General information detailing this substance ele-1: All FHIR elements must have a @value or children
molecularWeight | Σ | 0..* | BackboneElement | The average mass of a molecule of a compound ele-1: All FHIR elements must have a @value or children
extension |  | 0..* | Extension | Additional content defined by implementations ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
modifierExtension | ?!Σ | 0..* | Extension | Extensions that cannot be ignored even if unrecognized ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
method | Σ | 0..1 | CodeableConcept | The method by which the weight was determined Binding: ?? (example): The method by which the substance weight was measured. ele-1: All FHIR elements must have a @value or children
type | Σ | 0..1 | CodeableConcept | Type of molecular weight e.g. exact, average, weight average Binding: ?? (example): The type of substance weight measurement. ele-1: All FHIR elements must have a @value or children
amount | Σ | 1..1 | Quantity | Used to capture quantitative values for a variety of elements ele-1: All FHIR elements must have a @value or children
structure | Σ | 0..1 | BackboneElement | Structural information ele-1: All FHIR elements must have a @value or children
extension |  | 0..* | Extension | Additional content defined by implementations ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
modifierExtension | ?!Σ | 0..* | Extension | Extensions that cannot be ignored even if unrecognized ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
stereochemistry | Σ | 0..1 | CodeableConcept | Stereochemistry type Binding: ?? (example): The optical rotation type of a substance. ele-1: All FHIR elements must have a @value or children
opticalActivity | Σ | 0..1 | CodeableConcept | Optical activity type Binding: ?? (example): The optical rotation type of a substance. ele-1: All FHIR elements must have a @value or children
molecularFormula | Σ | 0..1 | string | An expression which states the number and type of atoms present in a molecule of a substance ele-1: All FHIR elements must have a @value or children
molecularFormulaByMoiety | Σ | 0..1 | string | Specified per moiety according to the Hill system ele-1: All FHIR elements must have a @value or children
molecularWeight | Σ | 0..1 |  | The molecular weight or weight range ele-1: All FHIR elements must have a @value or children
technique | Σ | 0..* | CodeableConcept | The method used to find the structure e.g. X-ray, NMR Binding: ?? (example): The method used to elucidate the structure of the drug substance. ele-1: All FHIR elements must have a @value or children
sourceDocument | Σ | 0..* | Reference(DocumentReference) | Source of information for the structure ele-1: All FHIR elements must have a @value or children
representation | Σ | 0..* | BackboneElement | A depiction of the structure of the substance ele-1: All FHIR elements must have a @value or children
extension |  | 0..* | Extension | Additional content defined by implementations ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
modifierExtension | ?!Σ | 0..* | Extension | Extensions that cannot be ignored even if unrecognized ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
type | Σ | 0..1 | CodeableConcept | The kind of structural representation (e.g. full, partial) Binding: ?? (example): A format of a substance representation. ele-1: All FHIR elements must have a @value or children
representation | Σ | 0..1 | string | The structural representation as a text string in a standard format ele-1: All FHIR elements must have a @value or children
format | Σ | 0..1 | CodeableConcept | The format of the representation e.g. InChI, SMILES, MOLFILE (note: not the physical file format) Binding: ?? (example): A format of a substance representation. ele-1: All FHIR elements must have a @value or children
document | Σ | 0..1 | Reference(DocumentReference) | An attachment with the structural representation e.g. a structure graphic or AnIML file ele-1: All FHIR elements must have a @value or children
code | Σ | 0..* | BackboneElement | Codes associated with the substance ele-1: All FHIR elements must have a @value or children
extension |  | 0..* | Extension | Additional content defined by implementations ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
modifierExtension | ?!Σ | 0..* | Extension | Extensions that cannot be ignored even if unrecognized ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
code | Σ | 0..1 | CodeableConcept | The specific code ele-1: All FHIR elements must have a @value or children
status | Σ | 0..1 | CodeableConcept | Status of the code assignment, for example 'provisional', 'approved' Binding: ?? (preferred): The lifecycle status of an artifact. ele-1: All FHIR elements must have a @value or children
statusDate | Σ | 0..1 | dateTime | The date at which the code status was changed ele-1: All FHIR elements must have a @value or children
note | Σ | 0..* | Annotation | Any comment can be provided in this field ele-1: All FHIR elements must have a @value or children
source | Σ | 0..* | Reference(DocumentReference) | Supporting literature ele-1: All FHIR elements must have a @value or children
name | S Σ | 0..* | BackboneElement | Names applicable to this substance ele-1: All FHIR elements must have a @value or children
extension |  | 0..* | Extension | Additional content defined by implementations ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
modifierExtension | ?!Σ | 0..* | Extension | Extensions that cannot be ignored even if unrecognized ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
name | Σ | 1..1 | string | The actual name ele-1: All FHIR elements must have a @value or children
type | Σ | 0..1 | CodeableConcept | Name type e.g. 'systematic', 'scientific, 'brand' Binding: ?? (example): The type of a name given to a substance. ele-1: All FHIR elements must have a @value or children
status | Σ | 0..1 | CodeableConcept | The status of the name e.g. 'current', 'proposed' Binding: ?? (preferred): The lifecycle status of an artifact. ele-1: All FHIR elements must have a @value or children
preferred | Σ | 0..1 | boolean | If this is the preferred name for this substance ele-1: All FHIR elements must have a @value or children
language | Σ | 0..* | CodeableConcept | Human language that the name is written in Binding: ?? (required): IETF language tag for a human language ele-1: All FHIR elements must have a @value or children
domain | Σ | 0..* | CodeableConcept | The use context of this name e.g. as an active ingredient or as a food colour additive Binding: ?? (example): The use context of a substance name for example if there is a different name when used as a drug active ingredient as opposed to a food colour additive. ele-1: All FHIR elements must have a @value or children
jurisdiction | Σ | 0..* | CodeableConcept | The jurisdiction where this name applies Binding: ?? (example): Jurisdiction codes ele-1: All FHIR elements must have a @value or children
synonym | Σ | 0..* |  | A synonym of this particular name, by which the substance is also known ele-1: All FHIR elements must have a @value or children
translation | Σ | 0..* |  | A translation for this name into another human language ele-1: All FHIR elements must have a @value or children
official | Σ | 0..* | BackboneElement | Details of the official nature of this name ele-1: All FHIR elements must have a @value or children
extension |  | 0..* | Extension | Additional content defined by implementations ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
modifierExtension | ?!Σ | 0..* | Extension | Extensions that cannot be ignored even if unrecognized ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
authority | Σ | 0..1 | CodeableConcept | Which authority uses this official name Binding: ?? (preferred): An authority that officates substance names. ele-1: All FHIR elements must have a @value or children
status | Σ | 0..1 | CodeableConcept | The status of the official name, for example 'draft', 'active' Binding: ?? (preferred): The lifecycle status of an artifact. ele-1: All FHIR elements must have a @value or children
date | Σ | 0..1 | dateTime | Date of official name change ele-1: All FHIR elements must have a @value or children
source | Σ | 0..* | Reference(DocumentReference) | Supporting literature ele-1: All FHIR elements must have a @value or children
relationship | S Σ | 0..* | BackboneElement | A link between this substance and another ele-1: All FHIR elements must have a @value or children
extension |  | 0..* | Extension | left: Additional content defined by implementations; right: Extension ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
modifierExtension | ?!Σ | 0..* | Extension | Extensions that cannot be ignored even if unrecognized ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
substanceDefinition[x] | Σ | 0..1 |  | A pointer to another substance, as a resource or a representational code ele-1: All FHIR elements must have a @value or children
substanceDefinitionReference |  |  | Reference(SubstanceDefinition) |
substanceDefinitionCodeableConcept |  |  | CodeableConcept |
type | S Σ | 1..1 | CodeableConcept | For example "salt to parent", "active moiety" Binding: ?? (example): The relationship between two substance types. ele-1: All FHIR elements must have a @value or children
isDefining | Σ | 0..1 | boolean | For example where an enzyme strongly bonds with a particular substance, this is a defining relationship for that enzyme, out of several possible relationships ele-1: All FHIR elements must have a @value or children
amount[x] | Σ | 0..1 |  | A numeric factor for the relationship, e.g. that a substance salt has some percentage of active substance in relation to some other ele-1: All FHIR elements must have a @value or children
amountQuantity |  |  | Quantity |
amountRatio |  |  | Ratio |
amountString |  |  | string |
ratioHighLimitAmount | Σ | 0..1 | Ratio | For use when the numeric has an uncertain range ele-1: All FHIR elements must have a @value or children
comparator | Σ | 0..1 | CodeableConcept | An operator for the amount, for example "average", "approximately", "less than" Binding: ?? (example): The relationship between two substance types. ele-1: All FHIR elements must have a @value or children
source | Σ | 0..* | Reference(DocumentReference) | Supporting literature ele-1: All FHIR elements must have a @value or children
nucleicAcid | Σ | 0..1 | Reference(SubstanceNucleicAcid) | Data items specific to nucleic acids ele-1: All FHIR elements must have a @value or children
polymer | Σ | 0..1 | Reference(SubstancePolymer) | Data items specific to polymers ele-1: All FHIR elements must have a @value or children
protein | Σ | 0..1 | Reference(SubstanceProtein) | Data items specific to proteins ele-1: All FHIR elements must have a @value or children
sourceMaterial | S Σ | 0..1 | BackboneElement | Material or taxonomic/anatomical source ele-1: All FHIR elements must have a @value or children
extension |  | 0..* | Extension | Additional content defined by implementations ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
modifierExtension | ?!Σ | 0..* | Extension | Extensions that cannot be ignored even if unrecognized ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
type | Σ | 0..1 | CodeableConcept | Classification of the origin of the raw material. e.g. cat hair is an Animal source type Binding: ?? (example): A classification that provides the origin of the substance raw material. ele-1: All FHIR elements must have a @value or children
genus | Σ | 0..1 | CodeableConcept | The genus of an organism e.g. the Latin epithet of the plant/animal scientific name Binding: ?? (example): The genus of an organism, typically referring to the Latin epithet of the genus element of the plant/animal scientific name. ele-1: All FHIR elements must have a @value or children
species | Σ | 0..1 | CodeableConcept | The species of an organism e.g. the Latin epithet of the species of the plant/animal Binding: ?? (example): A species of origin a substance raw material. ele-1: All FHIR elements must have a @value or children
part | Σ | 0..1 | CodeableConcept | An anatomical origin of the source material within an organism Binding: ?? (example): An anatomical origin of the source material within an organism. ele-1: All FHIR elements must have a @value or children
countryOfOrigin | Σ | 0..* | CodeableConcept | The country or countries where the material is harvested Binding: ?? (required): Jurisdiction codes ele-1: All FHIR elements must have a @value or children
Documentation for this format