Generated Narrative: Questionnaire F8-1.2 Last updated: 2014-05-15 17:25:15+0000 LinkID Text Cardinality Type Description & Constraints MedicationOrOtherSubstances Questionnaire http://hl7.org/fhir/uv/sdc/Questionnaire/F8-1.2 #xD; Medication/header null 0..1 group #xD; Medication/DE2 Event ID: 1..1 string #xD; Medication/DE30 Initial Report Date (HERF Q1) 1..1 string #xD; Medication/SEC00 Medication or Other Substance 0..1 group #xD; Medication/SEC00.0 Use this form to report any patient safety event or unsafe condition involving a substance such as a medications, biological products, nutritional products, expressed human breast milk, medical gases, or contrast media. Do not complete this form if the event involves appropriateness of therapeutic choice or decision making (e.g., physician decision to prescribe medication despite known drug-drug interaction). If the event involves a device, please also complete the Device or Medical/Surgical Supply including Health Information Technology (HIT) form. Narrative detail can be captured on the Healthcare Event Reporting Form (HERF). 0..1 display #xD; Medication/SEC01/74080-3 null 1..1 group #xD; Medication/DE270 What type of medication/substance was involved? 1..1 open-choice Definition: http://example.org/AHRQ/data_element_identifier#Type%20of%20substance%20involved Value Set: ValueSet D1e551vs #xD; Medication/DE273 What type of medication? 1..1 open-choice Definition: http://example.org/AHRQ/data_element_identifier#Type%20of%20medication%20involved Value Set: ValueSet D1e639vs #xD; Medication/DE276 Please list all ingredients: 0..* string Definition: http://example.org/AHRQ/data_element_identifier#Compounded%20preparation%20ingredients #xD; Medication/DE279 What type of biological product? 0..1 open-choice Value Set: ValueSet D1e910vs #xD; Medication/DE282 What was the lot number of the vaccine? 1..1 string #xD; Medication/DE285 What type of nutritional product? 1..1 open-choice Value Set: ValueSet D1e1125vs #xD; Medication/DE288 Which of the following best characterizes the event? 1..1 open-choice Value Set: ValueSet D1e1558vs #xD; Medication/DE291 What was the incorrect action? 0..1 open-choice Value Set: ValueSet D1e746vs #xD; Medication/DE294 Which best describes the incorrect dose(s)? 1..1 open-choice Value Set: ValueSet D1e863vs #xD; Medication/DE297 Which best describes the incorrect timing? 1..1 open-choice Value Set: ValueSet D1e2109vs #xD; Medication/DE300 Which best describes the incorrect rate? 1..1 open-choice Value Set: ValueSet D1e2272vs #xD; Medication/DE303 Which best describes the incorrect strength or concentration? 1..1 open-choice Value Set: ValueSet D1e2489vs #xD; Medication/DE306 What was the expiration date? 1..1 string #xD; Medication/DE309 Was there a documented history of allergies or sensitivities to the medication/substance administered? 1..1 open-choice Value Set: ValueSet D1e2768vs #xD; Medication/DE312 What was the contraindication (potential or actual interaction)? 1..1 open-choice Value Set: ValueSet D1e2928vs #xD; Medication/DE315 At what stage in the process did the event originate, regardless of the stage at which it was discovered? 1..1 open-choice Value Set: ValueSet D1e3159vs #xD; Medication/SEC02/74078-7 null 1..* group #xD; Medication/SEC02/74078-7.0 Please provide the following medication details for any medications or other substances directly involved in the event. 0..1 display #xD; Medication/DE318 Generic name or investigational drug name 0..1 string #xD; Medication/DE319 Ingredient 0..1 string #xD; Medication/DE321 Brand name 0..1 string #xD; Medication/DE322 Brand name RXCUI 0..1 string #xD; Medication/DE324 Manufacturer 0..1 string #xD; Medication/DE327 Strength or concentration of product 0..1 string #xD; Medication/DE328 Clinical Component RXCUI 0..1 string #xD; Medication/DE330 Dosage form of Product 0..1 string #xD; Medication/DE331 Dose form RXCUI 0..1 string #xD; Medication/DE333 Was this medication/substance prescribed for this patient? 1..1 open-choice Value Set: ValueSet D1e4024vs #xD; Medication/DE336 Was this medication/substance given to this patient? 1..1 open-choice Value Set: ValueSet D1e4118vs #xD; Medication/SEC03 null 0..1 group #xD; Medication/DE348 What was the intended route of administration? 1..1 open-choice Value Set: ValueSet D1e4236vs #xD; Medication/DE351 What was the actual route of administration (attempted or completed)? 1..1 open-choice Value Set: ValueSet D1e4716vs #xD; Medication/SEC04 STOP 0..1 group #xD; Medication/SEC04.0 The form is complete. 0..1 display #xD; Medication/SEC05 Thank you for completing these questions. 0..1 group #xD; Medication/SEC05.0 OMB No. 0935-0143 Exp. Date 10/31/2014 Public reporting burden for the collection of information is estimated to average 10 minutes per response. An agency may not conduct or sponsor, and a person is not required to respond to, a collection of information unless it displays a currently valid OMB control number. Send comments regarding this burden estimate or any other aspect of this collection of information, including suggestions for reducing this burden, to: AHRQ Reports Clearance Officer, Attention: PRA, Paperwork Reduction Project (0935-0143), AHRQ, 540 Gaither Road, Room #5036, Rockville, MD 20850. 0..1 display #xD; Medication/footer null 0..1 group #xD; Medication/footer.0 AHRQ Common Formats - Hospital Version 1.2 - 2012 Medication or Other Substance 0..1 display #xD; Documentation for this format Contained Resources CodeSystem #d1e551-cs url: http://example.org/AHRQ/form/question_identifier#Medication/DE270-cs name: MedicationDE270cs status: Active caseSensitive: true content: Complete concept code: A1197 display: Medications definition: A legal drug that is used to prevent, treat, or relieve symptoms of a disease or abnormal condition. concept code: A1200 display: Biological products definition: Organisms or complex pharmaceutical substances, preparations, or agents of organic origin, usually obtained by biological methods or assay. concept code: A1203 display: Nutritional products concept code: A1206 display: Expressed human breast milk concept code: A1209 display: Medical gases (e.g., oxygen, nitrogen, nitrous oxide) concept code: A1212 display: Contrast media concept code: A1213 display: Radiopharmaceuticals concept code: A1214 display: Patient food (not suspected in drug-food interactions concept code: A1216 display: Drug-drug, drug-food, or adverse drug reaction as a result of a prescription and/or administration of a drug and/or food frior to admission concept code: A1215 display: Other substance: PLEASE SPECIFY ValueSet #d1e551-vs name: D1e551vs status: Active compose Includes - System * http://example.org/AHRQ/form/question_identifier#Medication/DE270-cs CodeSystem #d1e639-cs url: http://example.org/AHRQ/form/question_identifier#Medication/DE273-cs name: MedicationDE273cs status: Active caseSensitive: true content: Complete concept code: A1218 display: Prescription or over-the-counter (including herbal supplements) concept code: A1221 display: Compounded preparations concept code: A1224 display: Investigational drugs concept code: UNK display: Unknown ValueSet #d1e639-vs url: http://hl7.org/fhir/uv/sdc/ValueSet/d1e639-vs name: D1e639vs status: Active compose Includes - System * http://example.org/AHRQ/form/question_identifier#Medication/DE273-cs CodeSystem #d1e910cs url: http://example.org/AHRQ/form/question_identifier#Medication/DE279-cs name: MedicationDE279cs status: Active caseSensitive: true content: Complete concept code: A1233 display: Vaccines concept code: A1236 display: Other biological products (e.g., thrombolytic) ValueSet #d1e910-vs name: D1e910vs status: Active compose Includes - System * http://example.org/AHRQ/form/question_identifier#Medication/DE279-cs CodeSystem #d1e1125-cs url: http://example.org/AHRQ/form/question_identifier#Medication/DE285-cs name: MedicationDE285cs status: Active caseSensitive: true content: Complete concept code: A1242 display: Dietary supplements (other than vitamins or minerals) concept code: A1245 display: Vitamins or minerals concept code: A1248 display: Enteral nutritional products, including infant formula concept code: A1251 display: Parenteral nutritional products concept code: A66 display: Other: PLEASE SPECIFY ValueSet #d1e1125-vs name: D1e1125vs status: Active compose Includes - System * http://example.org/AHRQ/form/question_identifier#Medication/DE285-cs CodeSystem #d1e1558-cs url: http://example.org/AHRQ/form/question_identifier#Medication/DE288-cs name: MedicationDE288cs status: Active caseSensitive: true content: Complete concept code: A1257 display: Incorrect action (process failure or error) (e.g., such as administering overdose or incorrect medication) concept code: A1260 display: Unsafe condition concept code: A1263 display: Adverse reaction in patient to the administered substance without any apparent incorrect action concept code: UNK display: Unknown ValueSet #d1e1558-vs name: D1e1558vs status: Active compose Includes - System * http://example.org/AHRQ/form/question_identifier#Medication/DE288-cs CodeSystem #d1e1746-cs url: http://example.org/AHRQ/form/question_identifier#Medication/DE291-cs name: MedicationDE291cs status: Active caseSensitive: true content: Complete concept code: A585 display: Incorrect patient concept code: A1272 display: Incorrect medication/substance concept code: A1275 display: Incorrect dose(s) concept code: A1278 display: Incorrect route of administration concept code: A1281 display: Incorrect timing concept code: A1284 display: Incorrect rate concept code: A1287 display: Incorrect duration of administration or course of therapy concept code: A1290 display: Incorrect dosage form (e.g., sustained release instead of immediate release) concept code: A1293 display: Incorrect strength or concentration concept code: A1296 display: Incorrect preparation, including inappropriate cutting of tablets, error in compounding, mixing, etc. concept code: A1299 display: Expired or deteriorated medication/substance concept code: A1301 display: Medication/substance that is known to be an allergen to the patient concept code: A1305 display: Medication/substance that is known to be contraindicated for the patient concept code: A1308 display: Incorrect patient/family action (e.g., self-administration error) concept code: A66 display: Other: PLEASE SPECIFY ValueSet #d1e1746-vs name: D1e746vs status: Active compose Includes - System * http://example.org/AHRQ/form/question_identifier#Medication/DE291-cs CodeSystem #d1e1863-cs url: http://example.org/AHRQ/form/question_identifier#Medication/DE294-cs name: MedicationDE294cs status: Active caseSensitive: true content: Complete concept code: A1314 display: Overdose concept code: A1317 display: Underdose concept code: A1320 display: Missed or omitted dose concept code: A1323 display: Extra dose concept code: UNK display: Unknown ValueSet #d1e1863-vs name: D1e863vs status: Active compose Includes - System * http://example.org/AHRQ/form/question_identifier#Medication/DE294-cs CodeSystem #d1e2109-cs url: http://example.org/AHRQ/form/question_identifier#Medication/DE297-cs name: MedicationDE297cs status: Active caseSensitive: true content: Complete concept code: A1329 display: Too early concept code: A1332 display: Too late concept code: UNK display: Unknown ValueSet #d1e2109-vs name: D1e2109vs status: Active compose Includes - System * http://example.org/AHRQ/form/question_identifier#Medication/DE297-cs CodeSystem #d1e2272-cs url: http://example.org/AHRQ/form/question_identifier#Medication/DE300-cs name: MedicationDE300cs status: Active caseSensitive: true content: Complete concept code: A1338 display: Too quickly concept code: A1341 display: Too slowly concept code: UNK display: Unknown ValueSet #d1e2272-vs name: D1e2272vs status: Active compose Includes - System * http://example.org/AHRQ/form/question_identifier#Medication/DE300-cs CodeSystem #d1e2489-cs url: http://example.org/AHRQ/form/question_identifier#Medication/DE303-cs name: MedicationDE303cs status: Active caseSensitive: true content: Complete concept code: A1347 display: Too high concept code: A1350 display: Too low concept code: UNK display: Unknown ValueSet #d1e2489-vs name: D1e2489vs status: Active compose Includes - System * http://example.org/AHRQ/form/question_identifier#Medication/DE303-cs CodeSystem #d1e2768-cs url: http://example.org/AHRQ/form/question_identifier#Medication/DE309-cs name: MedicationDE309cs status: Active caseSensitive: true content: Complete concept code: A15 display: Yes concept code: A18 display: No concept code: UNK display: Unknown ValueSet #d1e2768-vs name: D1e2768vs status: Active compose Includes - System * http://example.org/AHRQ/form/question_identifier#Medication/DE309-cs CodeSystem #d1e2928-cs url: http://example.org/AHRQ/form/question_identifier#Medication/DE312-cs name: MedicationDE312cs status: Active caseSensitive: true content: Complete concept code: A1368 display: Drug-drug concept code: A1371 display: Drug-food concept code: A1374 display: Drug-disease concept code: A66 display: Other: PLEASE SPECIFY ValueSet #d1e2928-vs name: D1e2928vs status: Active compose Includes - System * http://example.org/AHRQ/form/question_identifier#Medication/DE312-cs CodeSystem #d1e3159-cs url: http://example.org/AHRQ/form/question_identifier#Medication/DE315-cs name: MedicationDE315cs status: Active caseSensitive: true content: Complete concept code: A1380 display: Purchasing concept code: A1383 display: Storing concept code: A1386 display: Prescribing/ordering concept code: A1389 display: Transcribing concept code: A1392 display: Preparing concept code: A1395 display: Dispensing concept code: A1398 display: Administering concept code: A1401 display: Monitoring concept code: UNK display: Unknown concept code: A66 display: Other: PLEASE SPECIFY ValueSet #d1e3159-vs name: D1e3159vs status: Active compose Includes - System * http://example.org/AHRQ/form/question_identifier#Medication/DE315-cs CodeSystem #d1e4024-cs url: http://example.org/AHRQ/form/question_identifier#Medication/DE333-cs name: MedicationDE333cs status: Active caseSensitive: true content: Complete concept code: A15 display: Yes concept code: A18 display: No ValueSet #d1e4024-vs name: D1e4024vs status: Active compose Includes - System * http://example.org/AHRQ/form/question_identifier#Medication/DE333-cs CodeSystem #d1e4118-cs url: http://example.org/AHRQ/form/question_identifier#Medication/DE336-cs name: MedicationDE336cs status: Active caseSensitive: true content: Complete concept code: A15 display: Yes concept code: A18 display: No ValueSet #d1e4118-vs name: D1e4118vs status: Active compose Includes - System * http://example.org/AHRQ/form/question_identifier#Medication/DE336-cs CodeSystem #d1e4236-cs url: http://example.org/AHRQ/form/question_identifier#Medication/DE348-cs name: MedicationDE348cs status: Active caseSensitive: true content: Complete concept code: A1440 display: Cutaneous, topical application, including ointment, spray, patch concept code: A1443 display: Subcutaneous concept code: A1444 display: Ophthalmic concept code: A1446 display: Oral, including sublingual or buccal concept code: A1447 display: Otic concept code: A1449 display: Nasal concept code: A1450 display: Inhalation concept code: A1452 display: Intravenous concept code: A1455 display: Intramuscular concept code: A1458 display: Intrathecal concept code: A1461 display: Epidural concept code: A1464 display: Gastric concept code: A1467 display: Rectal concept code: A1470 display: Vaginal concept code: UNK display: Unknown concept code: A66 display: Other: PLEASE SPECIFY ValueSet #d1e4236-vs name: D1e4236vs status: Active compose Includes - System * http://example.org/AHRQ/form/question_identifier#Medication/DE348-cs CodeSystem #d1e4716-cs url: http://example.org/AHRQ/form/question_identifier#Medication/DE351-cs name: MedicationDE351cs status: Active caseSensitive: true content: Complete concept code: A1440 display: Cutaneous, topical application, including ointment, spray, patch concept code: A1443 display: Subcutaneous concept code: A1444 display: Ophthalmic concept code: A1446 display: Oral, including sublingual or buccal concept code: A1447 display: Otic concept code: A1449 display: Nasal concept code: A1450 display: Inhalation concept code: A1452 display: Intravenous concept code: A1455 display: Intramuscular concept code: A1458 display: Intrathecal concept code: A1461 display: Epidural concept code: A1464 display: Gastric concept code: A1467 display: Rectal concept code: A1470 display: Vaginal concept code: UNK display: Unknown concept code: A66 display: Other: PLEASE SPECIFY ValueSet #d1e4716-vs name: D1e4716vs status: Active compose Includes - System * http://example.org/AHRQ/form/question_identifier#Medication/DE351-cs
A legal drug that is used to prevent, treat, or relieve symptoms of a disease or abnormal condition.
Organisms or complex pharmaceutical substances, preparations, or agents of organic origin, usually obtained by biological methods or assay.
Medical gases (e.g., oxygen, nitrogen, nitrous oxide)
Patient food (not suspected in drug-food interactions
Drug-drug, drug-food, or adverse drug reaction as a result of a prescription and/or administration of a drug and/or food frior to admission
Prescription or over-the-counter (including herbal supplements)
Other biological products (e.g., thrombolytic)
Dietary supplements (other than vitamins or minerals)
Enteral nutritional products, including infant formula
Incorrect action (process failure or error) (e.g., such as administering overdose or incorrect medication)
Adverse reaction in patient to the administered substance without any apparent incorrect action
Incorrect duration of administration or course of therapy
Incorrect dosage form (e.g., sustained release instead of immediate release)
Incorrect preparation, including inappropriate cutting of tablets, error in compounding, mixing, etc.
Expired or deteriorated medication/substance
Medication/substance that is known to be an allergen to the patient
Medication/substance that is known to be contraindicated for the patient
Incorrect patient/family action (e.g., self-administration error)
Cutaneous, topical application, including ointment, spray, patch
Agency for Healthcare Research and Quality (AHRQ)
Use this form to report any patient safety event or unsafe condition involving a substance such as a medications, biological products, nutritional products, expressed human breast milk, medical gases, or contrast media. Do not complete this form if the event involves appropriateness of therapeutic choice or decision making (e.g., physician decision to prescribe medication despite known drug-drug interaction). If the event involves a device, please also complete the Device or Medical/Surgical Supply including Health Information Technology (HIT) form. Narrative detail can be captured on the Healthcare Event Reporting Form (HERF).
What type of medication/substance was involved?
Which of the following best characterizes the event?
Which best describes the incorrect dose(s)?
Which best describes the incorrect timing?
Which best describes the incorrect rate?
Which best describes the incorrect strength or concentration?
Was there a documented history of allergies or sensitivities to the medication/substance administered?
What was the contraindication (potential or actual interaction)?
At what stage in the process did the event originate, regardless of the stage at which it was discovered?
Please provide the following medication details for any medications or other substances directly involved in the event.
Generic name or investigational drug name
Was this medication/substance prescribed for this patient?
Was this medication/substance given to this patient?
What was the intended route of administration?
What was the actual route of administration (attempted or completed)?
Thank you for completing these questions.
OMB No. 0935-0143 Exp. Date 10/31/2014 Public reporting burden for the collection of information is estimated to average 10 minutes per response. An agency may not conduct or sponsor, and a person is not required to respond to, a collection of information unless it displays a currently valid OMB control number. Send comments regarding this burden estimate or any other aspect of this collection of information, including suggestions for reducing this burden, to: AHRQ Reports Clearance Officer, Attention: PRA, Paperwork Reduction Project (0935-0143), AHRQ, 540 Gaither Road, Room #5036, Rockville, MD 20850.
AHRQ Common Formats - Hospital Version 1.2 - 2012 Medication or Other Substance
Generated Narrative: Questionnaire HERF-1.2 Last updated: 2014-05-15 17:25:15+0000 LinkID Text Cardinality Type Description & Constraints Questionnaire http://hl7.org/fhir/uv/sdc/Questionnaire/HERF-1.2 #xD; HERF/header null 0..1 group #xD; HERF/DE2 Event ID 1..1 string #xD; HERF/DE30 Initial Report Date 1..1 string #xD; HERF/SEC01 null 0..1 group #xD; HERF/DE30b Report Date 1..1 string #xD; HERF/DE3 What is being reported? 1..1 open-choice Value Set: ValueSet: status = active #xD; HERF/DE15 Briefly describe the event that occurred or unsafe condition 1..* string #xD; HERF/DE18 Briefly describe the location where the event occurred or where the unsafe condition exists 1..* string #xD; HERF/DE21 Which of the following categories are associated with the event or unsafe condition? 1..* open-choice Value Set: ValueSet: status = active #xD; HERF/SEC01.1 PATIENT INFORMATION (COMPLETE ONLY IF INCIDENT) 0..1 group Enable When: HERF/DE3 = #xD; HERF/DE3.0 Please complete the patient identifiers below. Additional patient information is captured on the Patient Information Form (PIF). (When reporting a perinatal incident that affected a mother and a neonate, please complete the patient identifiers below for the mother (Q8 – Q11) and the neonate (Q12 – Q15). Please also complete a separate PIF for the neonate involved.) 0..1 display #xD; HERF/DE9a Event Discovery Date 1..1 string #xD; HERF/DE9b Event Discovery Time 1..1 string #xD; HERF/SEC02 Patient Information (COMPLETE ONLY IF INCIDENT): 0..1 group Enable When: HERF/DE3 = #xD; HERF/SEC02.0 Please complete the patient identifiers below. Additional patient information is captured on the Patient Information Form (PIF). (When reporting a perinatal incident that affected a mother and a neonate, please complete the patient identifiers below for the mother (Q8 – Q11) and the neonate (Q12 – Q15). Please also complete a separate PIF for the neonate involved.) 0..1 display #xD; HERF/DE46 Patient's Name 1..1 string #xD; HERF/DE47 Patient's Date of Birth 0..1 string #xD; HERF/DE49 Patient's Medical Record # 1..1 string #xD; HERF/DE42 Patients' Gender 0..1 open-choice Value Set: ValueSet: status = active #xD; HERF/SEC03 Neonatal Patient Information: 0..1 group #xD; HERF/SEC03.0 COMPLETE ONLY FOR NEONATE AFFECTED BY PERINATAL INCIDENT 0..1 display #xD; HERF/Hidden Is this event a perinatal incident that affected a neonate? 0..1 open-choice Value Set: ValueSet: status = active #xD; HERF/DE34 Neonate's Name 0..1 string #xD; HERF/DE37 Neonate's Date of Birth 0..1 string #xD; HERF/DE40 Neonate's Medical Record # 1..1 string #xD; HERF/DE43 Neonate's Gender 1..1 open-choice Value Set: ValueSet: status = active #xD; HERF/SEC04 REPORT AND EVENT REPORTER INFORMATION 0..1 group #xD; HERF/DE33 Anonymous Reporter 0..1 open-choice Value Set: ValueSet: status = active #xD; HERF/DE50 Reporter's Name 1..1 string #xD; HERF/DE52 Telephone Number 1..1 string #xD; HERF/DE53 Email Address 1..1 string #xD; HERF/DE36 Reporter's Job or Position 0..1 string #xD; HERF/SEC05 Thank you for completing these questions. 0..1 group #xD; HERF/SEC05.0 OMB No. 0935-0143 Exp. Date 10/31/2014 Public reporting burden for the collection of information is estimated to average 10 minutes per response. An agency may not conduct or sponsor, and a person is not required to respond to, a collection of information unless it displays a currently valid OMB control number. Send comments regarding this burden estimate or any other aspect of this collection of information, including suggestions for reducing this burden, to: AHRQ Reports Clearance Officer, Attention: PRA, Paperwork Reduction Project (0935-0143), AHRQ, 540 Gaither Road, Room #5036, Rockville, MD 20850. 0..1 display #xD; HERF/footer null 0..1 group #xD; HERF/footer.0 AHRQ Common Formats - Hospital Version 1.2 - 2012 Medication or Other Substance 0..1 display #xD; Documentation for this format Contained Resources CodeSystem #d1e5879-cs url: http://example.org/AHRQ/form/question_identifier#HERF/DE3-cs status: Active caseSensitive: true content: Complete concept code: A3 display: Incident definition: A patient safety event that reached the patient, whether or not the patient was harmed. concept code: A6 display: Near Miss definition: A patient safety event that did not reach the patient. concept code: A9 display: Unsafe Condition definition: Any circumstance that increases the probability of a patient safety event. ValueSet #d1e5879-vs status: Active compose Includes - System * http://example.org/AHRQ/form/question_identifier#HERF/DE3-cs CodeSystem #d1e6177-cs url: http://example.org/AHRQ/form/question_identifier#HERF/DE21-cs status: Active caseSensitive: true content: Complete concept code: A42 display: Blood or Blood Product concept code: A44 display: Device or Medical/Surgical Supply, including Health Information Technology (HIT) concept code: A48 display: Fall concept code: A51 display: Healthcare-associated Infection concept code: A54 display: Medication or Other Substance concept code: A57 display: Perinatal concept code: A60 display: Pressure Ulcer concept code: A63 display: Surgery or Anesthesia (includes invasive procedure) concept code: A64 display: Venous Thromboembolism concept code: A66 display: Other: PLEASE SPECIFY ValueSet #d1e6177-vs status: Active compose Includes - System * http://example.org/AHRQ/form/question_identifier#HERF/DE21-cs CodeSystem #d1e6853-cs url: http://example.org/AHRQ/form/question_identifier#HERF/DE42-cs status: Active caseSensitive: true content: Complete concept code: M display: Male concept code: F display: Female concept code: UNK display: Unknown ValueSet #d1e6853-vs status: Active compose Includes - System * http://example.org/AHRQ/form/question_identifier#HERF/DE42-cs CodeSystem #d1e7006-cs url: http://example.org/AHRQ/form/question_identifier#HERF/Hidden-cs status: Active caseSensitive: true content: Complete concept code: A15 display: Yes concept code: A18 display: No ValueSet #d1e7006-vs status: Active compose Includes - System * http://example.org/AHRQ/form/question_identifier#HERF/Hidden-cs CodeSystem #d1e7220-cs url: http://example.org/AHRQ/form/question_identifier#HERF/DE43-cs status: Active caseSensitive: true content: Complete concept code: M display: Male concept code: F display: Female concept code: UNK display: Unknown ValueSet #d1e7220-vs status: Active compose Includes - System * http://example.org/AHRQ/form/question_identifier#HERF/DE43-cs CodeSystem #d1e7422-cs url: http://example.org/AHRQ/form/question_identifier#HERF/DE33-cs status: Active caseSensitive: true content: Complete concept code: A15 display: Yes concept code: A18 display: No ValueSet #d1e7422-vs status: Active compose Includes - System * http://example.org/AHRQ/form/question_identifier#HERF/DE33-cs
A patient safety event that reached the patient, whether or not the patient was harmed.
A patient safety event that did not reach the patient.
Any circumstance that increases the probability of a patient safety event.
Device or Medical/Surgical Supply, including Health Information Technology (HIT)
Surgery or Anesthesia (includes invasive procedure)
Healthcare Event Reporting Form (HERF) Hospital Version 1.2
Briefly describe the event that occurred or unsafe condition
Briefly describe the location where the event occurred or where the unsafe condition exists
Which of the following categories are associated with the event or unsafe condition?
PATIENT INFORMATION (COMPLETE ONLY IF INCIDENT)
Please complete the patient identifiers below. Additional patient information is captured on the Patient Information Form (PIF). (When reporting a perinatal incident that affected a mother and a neonate, please complete the patient identifiers below for the mother (Q8 – Q11) and the neonate (Q12 – Q15). Please also complete a separate PIF for the neonate involved.)
Patient Information (COMPLETE ONLY IF INCIDENT):
COMPLETE ONLY FOR NEONATE AFFECTED BY PERINATAL INCIDENT
Is this event a perinatal incident that affected a neonate?
Generated Narrative: Questionnaire 3921052v1.0 Last updated: 2014-05-15 17:25:15+0000; Language: en LinkID Text Cardinality Type Description & Constraints Questionnaire http://hl7.org/fhir/uv/sdc/Questionnaire/3921052v1.0 #xD; 3921053v1.0 Mandatory Diagnosis Questions 1..1 group #xD; 3921053v1.0.0 These items must be included when this data is collected for reporting. 0..1 display #xD; 3921059v1.0 Date of Current Pathologic Diagnosis 0..1 string Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#62667v3.0 #xD; 3921060v1.0 Diagnosis Type 0..1 open-choice Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#3914869v1.0 Value Set: ValueSet D1e8086vs #xD; 3921065v1.0 Primary Site 0..1 string Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#3914972v1.0 #xD; 3921066v1.0 Conditional Diagnosis Questions 0..1 group #xD; 3921066v1.0.0 There are business rules to indicate situations under which these elements should be used on a case report form. 0..1 display #xD; 3921071v1.0 Diagnosis Time Point 0..1 open-choice Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#2816923v1.0 Value Set: ValueSet D1e8407vs #xD; 3921077v1.0 Optional Diagnosis Questions 0..1 group #xD; 3921077v1.0.0 There is no requirement for inclusion of these elements on the case report form. If the design and scientific questions posed in the study dictate the need to collect this type of data, these elements should be included. 0..1 display #xD; 3921079v1.0 Reviewing Pathologist 0..1 string Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#64320v3.0 #xD; 3921080v1.0 MedDRA disease code 0..1 string Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#2004425v4.0 #xD; 3921081v1.0 Assessment Method 0..1 open-choice Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#3914983v1.0 Value Set: ValueSet: status = active #xD; 3921085v1.0 Tumor grade 0..1 open-choice Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#2785839v2.0 Value Set: ValueSet: status = active #xD; Documentation for this format Contained Resources CodeSystem #d1e8086-cs url: http://example.org/nci.nih.gov/xml/owl/cadsr/form/form_design_identifier/3921052v1.0/question_identifier#3921060v1.0-cs name: D1e8086cs status: Active caseSensitive: true content: Complete concept code: Primary display: Primary Diagnosis definition: Occurring first in time or sequence; original; of greatest rank or importance or value.: The investigation, analysis and recognition of the presence and nature of disease, condition, or injury from expressed signs and symptoms; also, the scientific determination of any kind; the concise results of such an investigation. concept code: Secondary display: Secondary Diagnosis definition: Derived as a result of a primary condition; not direct or immediate; of second rank or importance or value.: The investigation, analysis and recognition of the presence and nature of disease, condition, or injury from expressed signs and symptoms; also, the scientific determination of any kind; the concise results of such an investigation. concept code: Treatment-related display: Treatment related secondary malignancy Diagnosis definition: A disorder characterized by development of a malignancy most probably as a result of treatment for a previously existing malignancy.: The investigation, analysis and recognition of the presence and nature of disease, condition, or injury from expressed signs and symptoms; also, the scientific determination of any kind; the concise results of such an investigation. concept code: Unknown display: Unknown definition: Not known, not observed, not recorded, or refused. ValueSet #d1e8086-vs name: D1e8086vs status: Active compose Includes - System * http://example.org/nci.nih.gov/xml/owl/cadsr/form/form_design_identifier/3921052v1.0/question_identifier#3921060v1.0-cs CodeSystem #d1e8407-cs url: http://example.org/nci.nih.gov/xml/owl/cadsr/form/form_design_identifier/3921052v1.0/question_identifier#3921071v1.0-cs name: D1e8407cs status: Active caseSensitive: true content: Complete concept code: Initial same as Current display: Initial diagnosis same as current definition: Initial diagnosis same as current concept code: At Progression display: Disease Progression definition: Cancer that continues to grow or spread. concept code: At Restaging display: Restaging definition: Two or more adjacent copies of an identical pattern.: The extent of a cancer within the body, especially whether the disease has spread from the original site to other parts of the body. concept code: Initial Diagnosis display: First Diagnosis definition: Preceding all others in time or space or degree.: The investigation, analysis and recognition of the presence and nature of disease, condition, or injury from expressed signs and symptoms; also, the scientific determination of any kind; the concise results of such an investigation. concept code: Current Diagnosis display: Current Diagnosis definition: Occurring in or belonging to the present time.: The investigation, analysis and recognition of the presence and nature of disease, condition, or injury from expressed signs and symptoms; also, the scientific determination of any kind; the concise results of such an investigation. ValueSet #d1e8407-vs name: D1e8407vs status: Active compose Includes - System * http://example.org/nci.nih.gov/xml/owl/cadsr/form/form_design_identifier/3921052v1.0/question_identifier#3921071v1.0-cs CodeSystem #d1e8830-cs url: http://example.org/nci.nih.gov/xml/owl/cadsr/form/form_design_identifier/3921052v1.0/question_identifier#3921081v1.0-cs status: Active caseSensitive: true content: Complete concept code: Cytologic display: Cytological Procedure definition: Technique or procedure for manipulation of cells and analysis of cell properties and subcellular features. concept code: Histologic display: Histological Procedure definition: Technique or procedure used for the study of the microanatomy of tissues and their cellular structure; usually involves microscopic examination of tissue slices. concept code: Histologic and Cytologic display: Histologic and Cytologic Procedures definition: Pertaining to the combined microscopic physical features of cells and their surrounding extracellular environment in tissues.: The light microscopic study of normal and abnormal cells in fine needle aspirates (FNAs), body cavity fluids, and smears.: Having been established or verified. ValueSet #d1e8830-vs status: Active compose Includes - System * http://example.org/nci.nih.gov/xml/owl/cadsr/form/form_design_identifier/3921052v1.0/question_identifier#3921081v1.0-cs CodeSystem #d1e9025-cs url: http://example.org/nci.nih.gov/xml/owl/cadsr/form/form_design_identifier/3921052v1.0/question_identifier#3921085v1.0-cs status: Active caseSensitive: true content: Complete concept code: G1 display: Well Differentiated definition: Describes tumor cells that generally retain the appearance of normal cells and tend to grow and spread at a slower rate than undifferentiated or poorly differentiated tumor cells. concept code: G2 display: Moderately Differentiated definition: Definition not available. concept code: G3 display: Poorly Differentiated definition: Describes tumor cells that generally have lost most of the appearance of normal cells. They tend to grow and spread. concept code: G4 display: Undifferentiated definition: A term used to describe cells or tissues that do not have specialized ("mature") structures or functions. Undifferentiated cancer cells often grow and spread quickly. concept code: GB display: Borderline Histologic Grade definition: Straddling the dividing line between two categories.: The degree of abnormality of cancer cells, a measure of differentiation, the extent to which cancer cells are similar in appearance and function to healthy cells of the same tissue type. The degree of differentiation often relates to the clinical behavior of the particular tumor. Based on the microscopic findings, tumor grade is commonly described by one of four degrees of severity. Histopathologic grade of a tumor may be used to plan treatment and estimate the future course, outcome, and overall prognosis of disease. Certain types of cancers, such as soft tissue sarcoma, primary brain tumors, lymphomas, and breast have special grading systems. concept code: GX display: Grade Cannot be Assessed definition: An operation in which a term denies or inverts the meaning of another term or construction.: Having determined the value, significance, or extent of.: The degree of abnormality of cancer cells, a measure of differentiation, the extent to which cancer cells are similar in appearance and function to healthy cells of the same tissue type. The degree of differentiation often relates to the clinical behavior of the particular tumor. Based on the microscopic findings, tumor grade is commonly described by one of four degrees of severity. Histopathologic grade of a tumor may be used to plan treatment and estimate the future course, outcome, and overall prognosis of disease. Certain types of cancers, such as soft tissue sarcoma, primary brain tumors, lymphomas, and breast have special grading systems. concept code: High Grade display: High Grade definition: Used to describe tumor samples that exhibit poorly differentiated or undifferentiated cells. They are generally expected to be fast growing and aggressive. concept code: Low Grade display: Low Grade definition: Used to describe tumor samples that exhibit well to moderately well differentiated cells. They are generally expected to be slow growing and less aggressive. ValueSet #d1e9025-vs status: Active compose Includes - System * http://example.org/nci.nih.gov/xml/owl/cadsr/form/form_design_identifier/3921052v1.0/question_identifier#3921085v1.0-cs
Occurring first in time or sequence; original; of greatest rank or importance or value.: The investigation, analysis and recognition of the presence and nature of disease, condition, or injury from expressed signs and symptoms; also, the scientific determination of any kind; the concise results of such an investigation.
Derived as a result of a primary condition; not direct or immediate; of second rank or importance or value.: The investigation, analysis and recognition of the presence and nature of disease, condition, or injury from expressed signs and symptoms; also, the scientific determination of any kind; the concise results of such an investigation.
Treatment related secondary malignancy Diagnosis
A disorder characterized by development of a malignancy most probably as a result of treatment for a previously existing malignancy.: The investigation, analysis and recognition of the presence and nature of disease, condition, or injury from expressed signs and symptoms; also, the scientific determination of any kind; the concise results of such an investigation.
Not known, not observed, not recorded, or refused.
Cancer that continues to grow or spread.
Two or more adjacent copies of an identical pattern.: The extent of a cancer within the body, especially whether the disease has spread from the original site to other parts of the body.
Preceding all others in time or space or degree.: The investigation, analysis and recognition of the presence and nature of disease, condition, or injury from expressed signs and symptoms; also, the scientific determination of any kind; the concise results of such an investigation.
Occurring in or belonging to the present time.: The investigation, analysis and recognition of the presence and nature of disease, condition, or injury from expressed signs and symptoms; also, the scientific determination of any kind; the concise results of such an investigation.
Technique or procedure for manipulation of cells and analysis of cell properties and subcellular features.
Technique or procedure used for the study of the microanatomy of tissues and their cellular structure; usually involves microscopic examination of tissue slices.
Pertaining to the combined microscopic physical features of cells and their surrounding extracellular environment in tissues.: The light microscopic study of normal and abnormal cells in fine needle aspirates (FNAs), body cavity fluids, and smears.: Having been established or verified.
Describes tumor cells that generally retain the appearance of normal cells and tend to grow and spread at a slower rate than undifferentiated or poorly differentiated tumor cells.
Describes tumor cells that generally have lost most of the appearance of normal cells. They tend to grow and spread.
A term used to describe cells or tissues that do not have specialized ("mature") structures or functions. Undifferentiated cancer cells often grow and spread quickly.
Straddling the dividing line between two categories.: The degree of abnormality of cancer cells, a measure of differentiation, the extent to which cancer cells are similar in appearance and function to healthy cells of the same tissue type. The degree of differentiation often relates to the clinical behavior of the particular tumor. Based on the microscopic findings, tumor grade is commonly described by one of four degrees of severity. Histopathologic grade of a tumor may be used to plan treatment and estimate the future course, outcome, and overall prognosis of disease. Certain types of cancers, such as soft tissue sarcoma, primary brain tumors, lymphomas, and breast have special grading systems.
An operation in which a term denies or inverts the meaning of another term or construction.: Having determined the value, significance, or extent of.: The degree of abnormality of cancer cells, a measure of differentiation, the extent to which cancer cells are similar in appearance and function to healthy cells of the same tissue type. The degree of differentiation often relates to the clinical behavior of the particular tumor. Based on the microscopic findings, tumor grade is commonly described by one of four degrees of severity. Histopathologic grade of a tumor may be used to plan treatment and estimate the future course, outcome, and overall prognosis of disease. Certain types of cancers, such as soft tissue sarcoma, primary brain tumors, lymphomas, and breast have special grading systems.
Used to describe tumor samples that exhibit poorly differentiated or undifferentiated cells. They are generally expected to be fast growing and aggressive.
Used to describe tumor samples that exhibit well to moderately well differentiated cells. They are generally expected to be slow growing and less aggressive.
These items must be included when this data is collected for reporting.
There are business rules to indicate situations under which these elements should be used on a case report form.
There is no requirement for inclusion of these elements on the case report form. If the design and scientific questions posed in the study dictate the need to collect this type of data, these elements should be included.
Generated Narrative: Questionnaire 2674812v4.0 Last updated: 2014-05-15 17:25:15+0000; Language: en LinkID Text Cardinality Type Description & Constraints Questionnaire http://hl7.org/fhir/uv/sdc/Questionnaire/2674812v4.0 #xD; 3702891v4.0 Mandatory Demography Questions 1..1 group #xD; 3702891v4.0.0 These items must be included when this data is collected for reporting 0..1 display #xD; 3702892v4.0 Gender 0..1 open-choice Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#2200604v3.0 Value Set: ValueSet: status = active #xD; 3702904v4.0 Race 0..1 open-choice Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#2192199v1.0 Value Set: ValueSet: status = active #xD; 3702903v4.0 Patient's Date of Birth 0..1 string Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#793v5.1 #xD; 3702898v4.0 Ethnicity 0..1 open-choice Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#2192217v2.0 Value Set: ValueSet: status = active #xD; 3702912v4.0 Conditional Demography Questions 0..1 group #xD; 3702912v4.0.0 There are business rules to indicate situations under which these elements should be used on a case report form. 0..1 display #xD; 3702914v4.0 ZIP Code 0..1 string Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#2179606v2.0 #xD; 3702916v4.0 Payment Method 0..1 open-choice Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#2865130v1.0 Value Set: ValueSet: status = active #xD; 3702932v4.0 Country of Residence 0..1 string Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#315v4.0 #xD; 3702934v4.0 Date Completed 0..1 string Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#2003745v5.0 #xD; 3702936v4.0 CDC Race Code 0..1 string Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#2200286v1.0 #xD; 3702938v4.0 CDC Ethnicity Code 0..1 string Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#2200284v2.0 #xD; 3702940v4.0 Optional Demography Questions 0..1 group #xD; 3702940v4.0.0 There is no requirement for inclusion of these elements on the case report form. If the design and scientific questions posed in the study dictate the need to collect this type of data, these elements should be included. 0..1 display #xD; 3702942v4.0 Highest Education Level 0..1 open-choice Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#2681552v1.0 Value Set: ValueSet: status = active #xD; 3702952v4.0 Country of Birth 0..1 open-choice Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#2001708v5.0 Value Set: ValueSet: status = active #xD; 3702957v4.0 Highest Education Level 0..1 open-choice Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#2674076v2.0 Value Set: ValueSet: status = active #xD; 3702984v4.0 Census Tract Code at Enrollment 0..1 string Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#2943243v1.0 #xD; 3702985v4.0 Marital Status 0..1 open-choice Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#2188083v2.0 Value Set: ValueSet: status = active #xD; Documentation for this format Contained Resources CodeSystem #d1e9892-cs url: http://example.org/nci.nih.gov/xml/owl/cadsr/form/form_design_identifier/2674812v4.0/question_identifier#3702892v4.0-cs status: Active caseSensitive: true content: Complete concept code: Female display: Female Gender definition: An individual who reports belonging to the cultural gender role distinction of female. concept code: Male display: Male Gender definition: An individual who reports belonging to the cultural gender role distinction of male. concept code: Unknown display: Unknown definition: Not known, not observed, not recorded, or refused. concept code: Unspecified display: Unspecified definition: Not stated explicitly or in detail. ValueSet #d1e9892-vs status: Active compose Includes - System * http://example.org/nci.nih.gov/xml/owl/cadsr/form/form_design_identifier/2674812v4.0/question_identifier#3702892v4.0-cs CodeSystem #d1e10146-cs url: http://example.org/nci.nih.gov/xml/owl/cadsr/form/form_design_identifier/2674812v4.0/question_identifier#3702904v4.0-cs status: Active caseSensitive: true content: Complete concept code: American Indian or Alaska Native display: American Indian or Alaska Native definition: A person having origins in any of the original peoples of North and South America (including Central America), and who maintains tribal affiliation or community attachment. concept code: Asian display: Asian definition: A person having origins in any of the original peoples of the Far East, Southeast Asia, or the Indian subcontinent including, for example, Cambodia, China, India, Japan, Korea, Malaysia, Pakistan, the Philippine Islands, Thailand, and Vietnam. concept code: Black or African American display: Black or African American definition: A person having origins in any of the black racial groups of Africa. Terms such as "Haitian" or "Negro" can be used in addition to "Black or African American." concept code: Native Hawaiian or other Pacific Islander display: Native Hawaiian or Other Pacific Islander definition: A person having origins in any of the original peoples of Hawaii, Guam, Samoa, or other Pacific Islands. concept code: Not Reported display: Not Reported definition: Not provided or available concept code: Unknown display: Unknown definition: Could not be determined or unsure concept code: White display: White definition: A person having origins in any of the original peoples of Europe, the Middle East, or North Africa. ValueSet #d1e10146-vs status: Active compose Includes - System * http://example.org/nci.nih.gov/xml/owl/cadsr/form/form_design_identifier/2674812v4.0/question_identifier#3702904v4.0-cs CodeSystem #d1e10593-cs url: http://example.org/nci.nih.gov/xml/owl/cadsr/form/form_design_identifier/2674812v4.0/question_identifier#3702898v4.0-cs status: Active caseSensitive: true content: Complete concept code: Hispanic or Latino display: Hispanic or Latino definition: A person of Mexican, Puerto Rican, Cuban, Central or South American or other Spanish culture or origin, regardless of race. concept code: Not Hispanic or Latino display: Not Hispanic or Latino definition: A person not meeting the definition for Hispanic or Latino. concept code: Not reported display: Not Reported definition: Not provided or available concept code: Unknown display: Unknown definition: Could not be determined or unsure ValueSet #d1e10593-vs status: Active compose Includes - System * http://example.org/nci.nih.gov/xml/owl/cadsr/form/form_design_identifier/2674812v4.0/question_identifier#3702898v4.0-cs CodeSystem #d1e10923-cs url: http://example.org/nci.nih.gov/xml/owl/cadsr/form/form_design_identifier/2674812v4.0/question_identifier#3702916v4.0-cs status: Active caseSensitive: true content: Complete concept code: Managed Care/Medicare display: Managed Care/Medicare definition: An arrangement whereby a third-party payer (e.g., insurance company, federal government, or corporation) mediates between physicians and patients, negotiating fees for service and overseeing the types of treatment given. Managed care has virtually replaced unmanaged indemnity plans, where payment is automatic and oversight procedures are minimal. Whereas 96% of American workers had unmanaged indemnity in 1984, only 28% did in 1988. Typically, in managed care, the third-party payer requires second opinions and pre-certification review for patients requiring hospital admission. They obtain wholesale prices from doctors, and carry out cost-containment measures, including auditing hospitals and reviewing claims. Managed care has figured heavily in the national debate over health care.: A program under the U.S. Social Security Administration that reimburses hospitals and physicians for medical care provided to qualifying people over 65 years old. concept code: Medicaid display: Medicaid definition: A jointly funded program of the United States federal and state governments that provides hospital expense and medical expense coverage to some people with low-income and certain aged and disabled individuals. concept code: Medicaid and Medicare display: Medicare And Medicaid definition: A program under the U.S. Social Security Administration that reimburses hospitals and physicians for medical care provided to qualifying people over 65 years old.: An article which expresses the relation of connection or addition. It is used to conjoin a word with a word, a clause with a clause, or a sentence with a sentence.: A jointly funded program of the United States federal and state governments that provides hospital expense and medical expense coverage to some people with low-income and certain aged and disabled individuals. concept code: Medicare display: Medicare definition: A program under the U.S. Social Security Administration that reimburses hospitals and physicians for medical care provided to qualifying people over 65 years old. concept code: Medicare and Private Insurance display: Medicare And Private Insurance definition: A program under the U.S. Social Security Administration that reimburses hospitals and physicians for medical care provided to qualifying people over 65 years old.: An article which expresses the relation of connection or addition. It is used to conjoin a word with a word, a clause with a clause, or a sentence with a sentence.: Not public; kept secret or restricted.: A mechanism for guarding against financial aspects of risk by making payments in the form of premiums to an insurance company, which pays an agreed-upon sum to the insured in the event of loss. concept code: Military or Veterans Sponsored, NOS display: Military Or Veterans Sponsored Insurance, Not Otherwise Specified definition: The armed forces of a country.: Or; used to connect words, phrases, or clauses representing alternatives; used to connect alternative terms for the same thing; used in correlation; used to correct or rephrase what was previously said; otherwise.: A division of the Executive Branch of the United States government concerned with overall planning, promoting, and administering programs pertaining to veterans. The Department of Veterans Affairs (VA) was established March 15, 1989 as a Cabinet-level position.: A person or organization that supports or champions something.: Not characterized in any other way.: A mechanism for guarding against financial aspects of risk by making payments in the form of premiums to an insurance company, which pays an agreed-upon sum to the insured in the event of loss. concept code: Military Sponsored (Including CHAMPUS & TriCare) display: Military Insurance definition: The armed forces of a country.: A mechanism for guarding against financial aspects of risk by making payments in the form of premiums to an insurance company, which pays an agreed-upon sum to the insured in the event of loss. concept code: No Means of Payment (No Insurance) display: No Insurance definition: The non-affirmative response to a question.: A mechanism for guarding against financial aspects of risk by making payments in the form of premiums to an insurance company, which pays an agreed-upon sum to the insured in the event of loss. concept code: Other display: Other definition: Not otherwise specified. concept code: Private Insurance display: Private Insurance definition: Not public; kept secret or restricted.: A mechanism for guarding against financial aspects of risk by making payments in the form of premiums to an insurance company, which pays an agreed-upon sum to the insured in the event of loss. concept code: Self-Pay (No Insurance) display: Self Payment definition: The individual as the object of his own reflective consciousness.: Payment; a sum of money paid. concept code: State Supplemental Health Insurance display: State Supplemental Health Insurance definition: A U.S. State is any one of the fifty states which is a member of the federation known as the United States of America. Other US geographic areas, such as Puerto Rico and the District of Columbia, are essentially equivalent to State when used in an address. (from Wikipedia and NCI): Something added to complete a thing, make up for a deficiency, or extend or strengthen the whole; serving to complete or make an addition.: The state of the organism when it functions optimally without evidence of disease.: A mechanism for guarding against financial aspects of risk by making payments in the form of premiums to an insurance company, which pays an agreed-upon sum to the insured in the event of loss. concept code: Unknown display: Unknown definition: Not known, not observed, not recorded, or refused. concept code: Veterans Sponsored display: Veterans Administration Sponsor Insurance definition: A division of the Executive Branch of the United States government concerned with overall planning, promoting, and administering programs pertaining to veterans. The Department of Veterans Affairs (VA) was established March 15, 1989 as a Cabinet-level position.: A person or organization that supports or champions something.: A mechanism for guarding against financial aspects of risk by making payments in the form of premiums to an insurance company, which pays an agreed-upon sum to the insured in the event of loss. ValueSet #d1e10923-vs status: Active compose Includes - System * http://example.org/nci.nih.gov/xml/owl/cadsr/form/form_design_identifier/2674812v4.0/question_identifier#3702916v4.0-cs CodeSystem #d1e11887-cs url: http://example.org/nci.nih.gov/xml/owl/cadsr/form/form_design_identifier/2674812v4.0/question_identifier#3702942v4.0-cs status: Active caseSensitive: true content: Complete concept code: Bachelor's Degree display: Bachelor's Degree definition: Bachelor's degree is an award (baccalaureate or equivalent degree, as determined by the Secretary of the U.S. Department of Education) conferred by a college, university, or other postsecondary education institution as official recognition for the successful completion of a program of studies, that normally requires at least four years of full-time equivalent college-level work. This includes bachelor's degrees conferred in a five-year cooperative program. concept code: Doctoral degree or professional degree display: Professional Doctorate or Doctorate Degree definition: A doctorate awarded in certain fields where most holders of the degree are not engaged primarily in scholarly research and academic activities, but rather in a profession, such as law, medicine, music, or ministry.: Or; used to connect words, phrases, or clauses representing alternatives; used to connect alternative terms for the same thing; used in correlation; used to correct or rephrase what was previously said; otherwise.: The Doctor's Degree is the highest award a student can earn for graduate study. The doctor's degree classification includes such degrees in any field. concept code: Grade School display: Grade School definition: A school for young children; usually the first 6 or 8 grades. concept code: Graduate or professional degree display: Graduation Or Professional Degree definition: Conferral or receipt of an academic degree or diploma marking the completion of a defined set of coursework.: Or; used to connect words, phrases, or clauses representing alternatives; used to connect alternative terms for the same thing; used in correlation; used to correct or rephrase what was previously said; otherwise.: An occupation requiring special education, especially in the liberal arts or sciences.: An academic degree is an award conferred by a college, university, or other postsecondary education institution as official recognition for the successful completion of a program of studies. concept code: High school graduate (including equivalency) display: High School Completion or General Equivalency Diploma (GED) Completion definition: Indicates that a person has attended high school and has received a high school diploma.: Or; used to connect words, phrases, or clauses representing alternatives; used to connect alternative terms for the same thing; used in correlation; used to correct or rephrase what was previously said; otherwise.: Indicates that a person has received a General Equivalency Diploma in lieu of a high school diploma. concept code: Master's Degree display: Master's Degree definition: The Master's Degree is an award that requires the successful completion of a program of study of at least the full-time equivalent of 1 but not more than two academic years of work beyond the bachelor's degree. concept code: No formal education display: No Formal Schooling definition: Indicates that a person has never attended an educational program or formal schooling. concept code: Not high school graduate display: Not High School Graduate definition: Indicates a person has attended high school but did not complete high school and did not receive a high school diploma. concept code: Some college or associate degree display: Some College or Associates Degree definition: An institution of higher education created to educate and grant degrees; often a part of a university.: At least a small amount or number of.: Or; used to connect words, phrases, or clauses representing alternatives; used to connect alternative terms for the same thing; used in correlation; used to correct or rephrase what was previously said; otherwise.: A degree granted by a two-year college on successful completion of the undergraduates course of studies. ValueSet #d1e11887-vs status: Active compose Includes - System * http://example.org/nci.nih.gov/xml/owl/cadsr/form/form_design_identifier/2674812v4.0/question_identifier#3702942v4.0-cs CodeSystem #d1e12384-cs url: http://example.org/nci.nih.gov/xml/owl/cadsr/form/form_design_identifier/2674812v4.0/question_identifier#3702952v4.0-cs status: Active caseSensitive: true content: Complete concept code: Other country display: Other country definition: Other country of birth. concept code: Other country, specify display: OTHER COUNTRY, SPECIFY definition: OTHER COUNTRY, SPECIFY concept code: USA display: USA definition: USA concept code: USA, specify the 2 letter State code, eg NY display: USA, SPECIFY THE 2 LETTER STATE CODE, EG NY definition: USA, SPECIFY THE 2 LETTER STATE CODE, EG NY ValueSet #d1e12384-vs status: Active compose Includes - System * http://example.org/nci.nih.gov/xml/owl/cadsr/form/form_design_identifier/2674812v4.0/question_identifier#3702952v4.0-cs CodeSystem #d1e12630-cs url: http://example.org/nci.nih.gov/xml/owl/cadsr/form/form_design_identifier/2674812v4.0/question_identifier#3702957v4.0-cs status: Active caseSensitive: true content: Complete concept code: 10th Grade display: 10th Grade definition: Indicates that 10th grade is the highest level of educational achievement concept code: 11th Grade display: 11th Grade definition: Indicates that 11th grade is the highest level of educational achievement concept code: 12th Grade No Diploma display: 12th Grade definition: Indicates that a person was in school through 12th grade but that they did not receive a high school diploma. concept code: 1st Grade display: 1st Grade definition: Indicates that 1st grade is the highest level of educational achievement. concept code: 2nd Grade display: 2nd Grade definition: Indicates that 2nd grade is the highest level of educational achievement. concept code: 3rd Grade display: 3rd Grade definition: Indicates that 3rd grade is the highest level of educational achievement. concept code: 4th Grade display: 4th Grade definition: Indicates that 4th grade is the highest level of educational achievement. concept code: 5th Grade display: 5th Grade definition: Indicates that 5th grade is the highest level of educational achievement. concept code: 6th Grade display: 6th Grade definition: Indicates that 6th grade is the highest level of educational achievement. concept code: 7th Grade display: 7th Grade definition: Indicates that 7th grade is the highest level of educational achievement concept code: 8th Grade display: 8th Grade definition: Indicates that 8th grade is the highest level of educational achievement concept code: 9th Grade display: 9th Grade definition: Indicates that 9th grade is the highest level of educational achievement concept code: Academic Doctorate Degree display: Academic Doctorate Degree Completion definition: Indicates that a person has received a degree the highest award earned for graduate study. concept code: Associate Degree display: Associate Degree definition: Indicates that a person has received a degree from a 2 year college program. concept code: Bachelor Degree display: Bachelor's Degree Completion definition: Indicates that a person has received a degree for successful completion of a program of studies that normally requires at least 4-5 years of full-time equivalent college-level work. concept code: Don't Know display: Does Not Know definition: The answer is not known by the person answering. concept code: General Equivalency Diploma display: General Equivalency Diploma definition: Indicates that a person has received a General Equivalency Diploma in lieu of a high school diploma. concept code: High School Graduate display: High School Graduate definition: Indicates that a person has attended high school and has received a high school diploma. concept code: Kindergarten display: Kindergarten Completion definition: Indicates that kindergarten is the highest level of education achievement. concept code: Master's Degree display: Master's Degree Completion definition: Indicates that a person has received a degree for completion of at least one year of prescribed study beyond the bachelor's degree. concept code: No Formal Schooling display: Never Attended definition: Indicates that a person never attended school or only attended kindergarten. concept code: Preschool display: Preschool Completion definition: Indicates that preschool is the highest level of education achievement. concept code: Professional Doctorate Degree display: Professional Doctorate Degree Completion definition: Indicates that a person has received a degree allowing them to practice a profession, such as law, medicine, music, or ministry. concept code: Refused display: Refuse definition: To decline to do, accept, give, or allow something. concept code: Some College, No Degree display: Some College definition: Indicates that a person has attended college but that they did not receive any degree. concept code: VoTech Program display: Vocational Degree definition: Indicates that a person has received a degree from a occupational, technical, or vocational program. ValueSet #d1e12630-vs status: Active compose Includes - System * http://example.org/nci.nih.gov/xml/owl/cadsr/form/form_design_identifier/2674812v4.0/question_identifier#3702957v4.0-cs CodeSystem #d1e14027-cs url: http://example.org/nci.nih.gov/xml/owl/cadsr/form/form_design_identifier/2674812v4.0/question_identifier#3702985v4.0-cs status: Active caseSensitive: true content: Complete concept code: Divorced display: Divorced: C51776 definition: A person whose marriage has been legally dissolved and has not remarried. concept code: Domestic Partnership display: Domestic Partner definition: A person who is a member of an unmarried couple, including same sex couples, living together in longstanding relationships, that are registered or unregistered. concept code: Married display: Married: C51773 definition: A person currently joined in matrimony. Classify common law marriage as married. Includes married couples living together and not living together. concept code: Never Married display: Never married definition: A person who has never been married or whose only marriages have been annulled. concept code: Separated display: SEPARATED definition: A person living apart from his/her spouse by legal arrangement. concept code: Widowed display: WIDOWED definition: A person who is no longer married because of the death of his/her spouse and who has not remarried. ValueSet #d1e14027-vs status: Active compose Includes - System * http://example.org/nci.nih.gov/xml/owl/cadsr/form/form_design_identifier/2674812v4.0/question_identifier#3702985v4.0-cs
An individual who reports belonging to the cultural gender role distinction of female.
An individual who reports belonging to the cultural gender role distinction of male.
A person having origins in any of the original peoples of North and South America (including Central America), and who maintains tribal affiliation or community attachment.
A person having origins in any of the original peoples of the Far East, Southeast Asia, or the Indian subcontinent including, for example, Cambodia, China, India, Japan, Korea, Malaysia, Pakistan, the Philippine Islands, Thailand, and Vietnam.
A person having origins in any of the black racial groups of Africa. Terms such as "Haitian" or "Negro" can be used in addition to "Black or African American."
Native Hawaiian or other Pacific Islander
A person having origins in any of the original peoples of Hawaii, Guam, Samoa, or other Pacific Islands.
A person having origins in any of the original peoples of Europe, the Middle East, or North Africa.
A person of Mexican, Puerto Rican, Cuban, Central or South American or other Spanish culture or origin, regardless of race.
A person not meeting the definition for Hispanic or Latino.
An arrangement whereby a third-party payer (e.g., insurance company, federal government, or corporation) mediates between physicians and patients, negotiating fees for service and overseeing the types of treatment given. Managed care has virtually replaced unmanaged indemnity plans, where payment is automatic and oversight procedures are minimal. Whereas 96% of American workers had unmanaged indemnity in 1984, only 28% did in 1988. Typically, in managed care, the third-party payer requires second opinions and pre-certification review for patients requiring hospital admission. They obtain wholesale prices from doctors, and carry out cost-containment measures, including auditing hospitals and reviewing claims. Managed care has figured heavily in the national debate over health care.: A program under the U.S. Social Security Administration that reimburses hospitals and physicians for medical care provided to qualifying people over 65 years old.
A jointly funded program of the United States federal and state governments that provides hospital expense and medical expense coverage to some people with low-income and certain aged and disabled individuals.
A program under the U.S. Social Security Administration that reimburses hospitals and physicians for medical care provided to qualifying people over 65 years old.: An article which expresses the relation of connection or addition. It is used to conjoin a word with a word, a clause with a clause, or a sentence with a sentence.: A jointly funded program of the United States federal and state governments that provides hospital expense and medical expense coverage to some people with low-income and certain aged and disabled individuals.
A program under the U.S. Social Security Administration that reimburses hospitals and physicians for medical care provided to qualifying people over 65 years old.
A program under the U.S. Social Security Administration that reimburses hospitals and physicians for medical care provided to qualifying people over 65 years old.: An article which expresses the relation of connection or addition. It is used to conjoin a word with a word, a clause with a clause, or a sentence with a sentence.: Not public; kept secret or restricted.: A mechanism for guarding against financial aspects of risk by making payments in the form of premiums to an insurance company, which pays an agreed-upon sum to the insured in the event of loss.
Military Or Veterans Sponsored Insurance, Not Otherwise Specified
The armed forces of a country.: Or; used to connect words, phrases, or clauses representing alternatives; used to connect alternative terms for the same thing; used in correlation; used to correct or rephrase what was previously said; otherwise.: A division of the Executive Branch of the United States government concerned with overall planning, promoting, and administering programs pertaining to veterans. The Department of Veterans Affairs (VA) was established March 15, 1989 as a Cabinet-level position.: A person or organization that supports or champions something.: Not characterized in any other way.: A mechanism for guarding against financial aspects of risk by making payments in the form of premiums to an insurance company, which pays an agreed-upon sum to the insured in the event of loss.
Military Sponsored (Including CHAMPUS & TriCare)
The armed forces of a country.: A mechanism for guarding against financial aspects of risk by making payments in the form of premiums to an insurance company, which pays an agreed-upon sum to the insured in the event of loss.
The non-affirmative response to a question.: A mechanism for guarding against financial aspects of risk by making payments in the form of premiums to an insurance company, which pays an agreed-upon sum to the insured in the event of loss.
Not public; kept secret or restricted.: A mechanism for guarding against financial aspects of risk by making payments in the form of premiums to an insurance company, which pays an agreed-upon sum to the insured in the event of loss.
The individual as the object of his own reflective consciousness.: Payment; a sum of money paid.
A U.S. State is any one of the fifty states which is a member of the federation known as the United States of America. Other US geographic areas, such as Puerto Rico and the District of Columbia, are essentially equivalent to State when used in an address. (from Wikipedia and NCI): Something added to complete a thing, make up for a deficiency, or extend or strengthen the whole; serving to complete or make an addition.: The state of the organism when it functions optimally without evidence of disease.: A mechanism for guarding against financial aspects of risk by making payments in the form of premiums to an insurance company, which pays an agreed-upon sum to the insured in the event of loss.
Veterans Administration Sponsor Insurance
A division of the Executive Branch of the United States government concerned with overall planning, promoting, and administering programs pertaining to veterans. The Department of Veterans Affairs (VA) was established March 15, 1989 as a Cabinet-level position.: A person or organization that supports or champions something.: A mechanism for guarding against financial aspects of risk by making payments in the form of premiums to an insurance company, which pays an agreed-upon sum to the insured in the event of loss.
Bachelor's degree is an award (baccalaureate or equivalent degree, as determined by the Secretary of the U.S. Department of Education) conferred by a college, university, or other postsecondary education institution as official recognition for the successful completion of a program of studies, that normally requires at least four years of full-time equivalent college-level work. This includes bachelor's degrees conferred in a five-year cooperative program.
Professional Doctorate or Doctorate Degree
A doctorate awarded in certain fields where most holders of the degree are not engaged primarily in scholarly research and academic activities, but rather in a profession, such as law, medicine, music, or ministry.: Or; used to connect words, phrases, or clauses representing alternatives; used to connect alternative terms for the same thing; used in correlation; used to correct or rephrase what was previously said; otherwise.: The Doctor's Degree is the highest award a student can earn for graduate study. The doctor's degree classification includes such degrees in any field.
A school for young children; usually the first 6 or 8 grades.
Conferral or receipt of an academic degree or diploma marking the completion of a defined set of coursework.: Or; used to connect words, phrases, or clauses representing alternatives; used to connect alternative terms for the same thing; used in correlation; used to correct or rephrase what was previously said; otherwise.: An occupation requiring special education, especially in the liberal arts or sciences.: An academic degree is an award conferred by a college, university, or other postsecondary education institution as official recognition for the successful completion of a program of studies.
High school graduate (including equivalency)
High School Completion or General Equivalency Diploma (GED) Completion
Indicates that a person has attended high school and has received a high school diploma.: Or; used to connect words, phrases, or clauses representing alternatives; used to connect alternative terms for the same thing; used in correlation; used to correct or rephrase what was previously said; otherwise.: Indicates that a person has received a General Equivalency Diploma in lieu of a high school diploma.
The Master's Degree is an award that requires the successful completion of a program of study of at least the full-time equivalent of 1 but not more than two academic years of work beyond the bachelor's degree.
Indicates that a person has never attended an educational program or formal schooling.
Indicates a person has attended high school but did not complete high school and did not receive a high school diploma.
An institution of higher education created to educate and grant degrees; often a part of a university.: At least a small amount or number of.: Or; used to connect words, phrases, or clauses representing alternatives; used to connect alternative terms for the same thing; used in correlation; used to correct or rephrase what was previously said; otherwise.: A degree granted by a two-year college on successful completion of the undergraduates course of studies.
USA, specify the 2 letter State code, eg NY
Indicates that 10th grade is the highest level of educational achievement
Indicates that 11th grade is the highest level of educational achievement
Indicates that a person was in school through 12th grade but that they did not receive a high school diploma.
Indicates that 1st grade is the highest level of educational achievement.
Indicates that 2nd grade is the highest level of educational achievement.
Indicates that 3rd grade is the highest level of educational achievement.
Indicates that 4th grade is the highest level of educational achievement.
Indicates that 5th grade is the highest level of educational achievement.
Indicates that 6th grade is the highest level of educational achievement.
Indicates that 7th grade is the highest level of educational achievement
Indicates that 8th grade is the highest level of educational achievement
Indicates that 9th grade is the highest level of educational achievement
Indicates that a person has received a degree the highest award earned for graduate study.
Indicates that a person has received a degree from a 2 year college program.
Indicates that a person has received a degree for successful completion of a program of studies that normally requires at least 4-5 years of full-time equivalent college-level work.
The answer is not known by the person answering.
Indicates that a person has received a General Equivalency Diploma in lieu of a high school diploma.
Indicates that a person has attended high school and has received a high school diploma.
Indicates that kindergarten is the highest level of education achievement.
Indicates that a person has received a degree for completion of at least one year of prescribed study beyond the bachelor's degree.
Indicates that a person never attended school or only attended kindergarten.
Indicates that preschool is the highest level of education achievement.
Professional Doctorate Degree Completion
Indicates that a person has received a degree allowing them to practice a profession, such as law, medicine, music, or ministry.
To decline to do, accept, give, or allow something.
Indicates that a person has attended college but that they did not receive any degree.
Indicates that a person has received a degree from a occupational, technical, or vocational program.
A person whose marriage has been legally dissolved and has not remarried.
A person who is a member of an unmarried couple, including same sex couples, living together in longstanding relationships, that are registered or unregistered.
A person currently joined in matrimony. Classify common law marriage as married. Includes married couples living together and not living together.
A person who has never been married or whose only marriages have been annulled.
A person living apart from his/her spouse by legal arrangement.
A person who is no longer married because of the death of his/her spouse and who has not remarried.
Generated Narrative: Questionnaire 3265657v2.0 Last updated: 2014-05-15 17:25:15+0000; Language: en LinkID Text Cardinality Type Description & Constraints A sample questionnaire example for sdc-questionnaire profile Questionnaire http://hl7.org/fhir/uv/sdc/Questionnaire/3265657v2.0 #xD; 3556213v2.0 Mandatory Adverse Event Questions 1..1 group #xD; 3556213v2.0.0 Must be included when this data is collected for reporting. 0..1 display #xD; 3556214v2.0 Adverse Event Term (v4.0) 0..1 open-choice Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#3125302v1.1 Value Set: ValueSet: status = active #xD; 3557006v2.0 Describe 'Other' Adverse Event 0..1 string Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#2188132v1.0 #xD; 3557008v2.0 Adverse Event Grade 0..1 open-choice Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#2944515v1.0 Value Set: ValueSet: status = active #xD; 3557016v2.0 Conditional Adverse Event Questions 0..1 group #xD; 3557016v2.0.0 There are business rules to indicate situations under which this data element should be used in a CRF. 0..1 display #xD; 3557017v2.0 AE Start Date 0..1 string Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#2744993v1.0 #xD; 3557021v2.0 Was patient hospitalized for toxicity? 0..1 open-choice Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#2552398v1.0 Value Set: ValueSet: status = active #xD; 3557025v2.0 Cycle # 0..1 string Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#2744948v1.0 #xD; 3557027v2.0 Optional Adverse Event Questions 0..1 group #xD; 3557027v2.0.0 No requirement for inclusion of this element on the CRF; if the design and scientific questions posed in the study dictate the need to collect this type of data, this is the element to include on the CRF. 0..1 display #xD; 3557032v2.0 To what is the AE attributed? 0..1 open-choice Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#2179892v2.0 Value Set: ValueSet: status = active #xD; 3557863v2.0 Other Attribution, Specify 0..1 string Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#2201348v1.0 #xD; 3557046v2.0 AE Stop Date 0..1 string Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#2189843v1.0 #xD; 3557869v2.0 MedDRA System Organ Class (SOC) 0..1 open-choice Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#2943864v1.0 Value Set: ValueSet: status = active #xD; 3557050v2.0 MedDRA AE Code (CTCAE v4.0) 0..1 open-choice Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#3133353v1.0 Value Set: ValueSet: status = active #xD; 3557842v2.0 AE Attribution 0..1 open-choice Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#1285v3.0 Value Set: ValueSet: status = active #xD; 3557849v2.0 Reporting Period End Date 0..1 string Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#2006851v4.0 #xD; 3557851v2.0 Were adverse events assessed during most recent period 0..1 open-choice Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#2179971v1.0 Value Set: ValueSet: status = active #xD; 3557856v2.0 Expected? (Yes/No) 0..1 open-choice Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#2183619v1.0 Value Set: ValueSet: status = active #xD; 3557859v2.0 Serious? 0..1 open-choice Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#2199908v1.0 Value Set: ValueSet: status = active #xD; 3557911v2.0 Event Onset Time 0..1 string Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#2585234v1.0 #xD; 3557865v2.0 Course 0..1 string Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#2732184v1.0 #xD; 3557867v2.0 AE Evaluation Period Start Date 0..1 string Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#2744943v1.0 #xD; 3557913v2.0 Pre-existing AE? 0..1 open-choice Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#2746280v1.0 Value Set: ValueSet: status = active #xD; 3557904v2.0 AE Resolved Time 0..1 string Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#2746301v1.0 #xD; 3557028v2.0 AE Ongoing? 0..1 open-choice Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#2746311v1.0 Value Set: ValueSet: status = active #xD; 3557896v2.0 Participant Status/Outcome 0..1 open-choice Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#2746517v1.0 Value Set: ValueSet: status = active #xD; 3557906v2.0 Adverse Event Condition Pattern 0..1 open-choice Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#2008418v1.0 Value Set: ValueSet: status = active #xD; 3557917v2.0 Did event reappear after study agent was reintroduced? 0..1 open-choice Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#2179615v1.0 Value Set: ValueSet: status = active #xD; 3557922v2.0 Comments 0..1 string Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#797v5.0 #xD; 3556197v2.0 Optional Serious Adverse Event Questions 0..1 group #xD; 3556197v2.0.0 The following additional elements are optional on a SAE form. 0..1 display #xD; 3556199v2.0 Why serious? 0..1 open-choice Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#2179679v3.0 Value Set: ValueSet: status = active #xD; 3556209v2.0 Dose-Limiting Toxicity? 0..1 open-choice Definition: http://example.org/nci.nih.gov/xml/owl/cadsr/data_element_scoped_identifier#2004106v3.0 Value Set: ValueSet: status = active #xD; Documentation for this format Contained Resources CodeSystem #d1e14927-cs url: http://example.org/nci.nih.gov/xml/owl/cadsr/form/form_design_identifier/3265657v2.0/question_identifier#3556214v2.0-cs status: Active caseSensitive: true content: Complete concept code: Abdominal distension display: Abdominal distension definition: A disorder characterized by swelling of the abdomen. concept code: Abdominal infection display: Abdominal infection definition: A disorder characterized by an infectious process involving the abdominal cavity. concept code: Abdominal pain display: Abdominal pain definition: A disorder characterized by a sensation of marked discomfort in the abdominal region. concept code: Abdominal soft tissue necrosis display: Abdominal soft tissue necrosis definition: A disorder characterized by a necrotic process occurring in the soft tissues of the abdominal wall. concept code: Abducens nerve disorder display: Abducens nerve disorder definition: A disorder characterized by involvement of the abducens nerve (sixth cranial nerve). concept code: Accessory nerve disorder display: Accessory nerve disorder definition: A disorder characterized by involvement of the accessory nerve (eleventh cranial nerve). concept code: Acidosis display: Acidosis definition: A disorder characterized by abnormally high acidity (high hydrogen-ion concentration) of the blood and other body tissues. concept code: Acoustic nerve disorder NOS display: Acoustic nerve disorder NOS definition: A disorder characterized by involvement of the acoustic nerve (eighth cranial nerve). concept code: Activated partial thromboplastin time prolonged display: Activated partial thromboplastin time prolonged definition: An abnormal laboratory test result in which the partial thromboplastin time is found to be greater than the control value. As a possible indicator of coagulopathy, a prolonged partial thromboplastin time (PTT) may occur in a variety of diseases and disorders, both primary and related to treatment. concept code: Acute coronary syndrome display: Acute coronary syndrome definition: A disorder characterized by signs and symptoms related to acute ischemia of the myocardium secondary to coronary artery disease. The clinical presentation covers a spectrum of heart diseases from unstable angina to myocardial infarction. concept code: Acute kidney injury display: Acute kidney injury definition: A disorder characterized by the acute loss of renal function and is traditionally classified as pre-renal (low blood flow into kidney), renal (kidney damage) and post-renal causes (ureteral or bladder outflow obstruction). concept code: Adrenal insufficiency display: Adrenal insufficiency definition: A disorder that occurs when the adrenal cortex does not produce enough of the hormone cortisol and in some cases, the hormone aldosterone. It may be due to a disorder of the adrenal cortex as in Addison's disease or primary adrenal insufficiency. concept code: Adult respiratory distress syndrome display: Adult respiratory distress syndrome definition: A disorder characterized by progressive and life-threatening pulmonary distress in the absence of an underlying pulmonary condition, usually following major trauma or surgery. concept code: Agitation display: Agitation definition: A disorder characterized by a state of restlessness associated with unpleasant feelings of irritability and tension. concept code: Akathisia display: Akathisia definition: A disorder characterized by an uncomfortable feeling of inner restlessness and inability to stay still; this is a side effect of some psychotropic drugs. concept code: Alanine aminotransferase increased display: Alanine aminotransferase increased definition: A finding based on laboratory test results that indicate an increase in the level of alanine aminotransferase (ALT or SGPT) in the blood specimen. concept code: Alcohol intolerance display: Alcohol intolerance definition: A disorder characterized by an increase in sensitivity to the adverse effects of alcohol, which can include nasal congestion, skin flushes, heart dysrhythmias, nausea, vomiting, indigestion and headaches. concept code: Alkaline phosphatase increased display: Alkaline phosphatase increased definition: A finding based on laboratory test results that indicate an increase in the level of alkaline phosphatase in a blood specimen. concept code: Alkalosis display: Alkalosis definition: A disorder characterized by abnormally high alkalinity (low hydrogen-ion concentration) of the blood and other body tissues. concept code: Allergic reaction display: Allergic reaction definition: A disorder characterized by an adverse local or general response from exposure to an allergen. concept code: Allergic rhinitis display: Allergic rhinitis definition: A disorder characterized by an inflammation of the nasal mucous membranes caused by an IgE-mediated response to external allergens. The inflammation may also involve the mucous membranes of the sinuses, eyes, middle ear, and pharynx. Symptoms include sneezing, nasal congestion, rhinorrhea and itching. concept code: Alopecia display: Alopecia definition: A disorder characterized by a decrease in density of hair compared to normal for a given individual at a given age and body location. concept code: Amnesia display: Amnesia definition: A disorder characterized by systematic and extensive loss of memory. concept code: Anal fistula display: Anal fistula definition: A disorder characterized by an abnormal communication between the opening in the anal canal to the perianal skin. concept code: Anal hemorrhage display: Anal hemorrhage definition: A disorder characterized by bleeding from the anal region. concept code: Anal mucositis display: Anal mucositis definition: A disorder characterized by inflammation of the mucous membrane of the anus. concept code: Anal necrosis display: Anal necrosis definition: A disorder characterized by a necrotic process occurring in the anal region. concept code: Anal pain display: Anal pain definition: A disorder characterized by a sensation of marked discomfort in the anal region. concept code: Anal stenosis display: Anal stenosis definition: A disorder characterized by a narrowing of the lumen of the anal canal. concept code: Anal ulcer display: Anal ulcer definition: A disorder characterized by a circumscribed, inflammatory and necrotic erosive lesion on the mucosal surface of the anal canal. concept code: Anaphylaxis display: Anaphylaxis definition: A disorder characterized by an acute inflammatory reaction resulting from the release of histamine and histamine-like substances from mast cells, causing a hypersensitivity immune response. Clinically, it presents with breathing difficulty, dizziness, hypotension, cyanosis and loss of consciousness and may lead to death. concept code: Anemia display: Anemia definition: A disorder characterized by an reduction in the amount of hemoglobin in 100 ml of blood. Signs and symptoms of anemia may include pallor of the skin and mucous membranes, shortness of breath, palpitations of the heart, soft systolic murmurs, lethargy, and fatigability. concept code: Ankle fracture display: Ankle fracture definition: A finding of damage to the ankle joint characterized by a break in the continuity of the ankle bone. Symptoms include marked discomfort, swelling and difficulty moving the affected leg and foot. concept code: Anorectal infection display: Anorectal infection definition: A disorder characterized by an infectious process involving the anal area and the rectum. concept code: Anorexia display: Anorexia definition: A disorder characterized by a loss of appetite. concept code: Anorgasmia display: Anorgasmia definition: A disorder characterized by an inability to achieve orgasm. concept code: Anxiety display: Anxiety definition: A disorder characterized by apprehension of danger and dread accompanied by restlessness, tension, tachycardia, and dyspnea unattached to a clearly identifiable stimulus. concept code: Aortic injury display: Aortic injury definition: A finding of damage to the aorta. concept code: Aortic valve disease display: Aortic valve disease definition: A disorder characterized by a defect in aortic valve function or structure. concept code: Aphonia display: Aphonia definition: A disorder characterized by the inability to speak. It may result from injuries to the vocal cords or may be functional (psychogenic). concept code: Apnea display: Apnea definition: A disorder characterized by cessation of breathing. concept code: Appendicitis display: Appendicitis definition: A disorder characterized by acute inflammation to the vermiform appendix caused by a pathogenic agent. concept code: Appendicitis perforated display: Appendicitis perforated definition: A disorder characterized by acute inflammation to the vermiform appendix caused by a pathogenic agent with gangrenous changes resulting in the rupture of the appendiceal wall. The appendiceal wall rupture causes the release of inflammatory and bacterial contents from the appendiceal lumen into the abdominal cavity. concept code: Arachnoiditis display: Arachnoiditis definition: A disorder characterized by inflammation of the arachnoid membrane and adjacent subarachnoid space. concept code: Arterial injury display: Arterial injury definition: A finding of damage to an artery. concept code: Arteritis infective display: Arteritis infective definition: A disorder characterized by an infectious process involving an artery. concept code: Arthralgia display: Arthralgia definition: A disorder characterized by a sensation of marked discomfort in a joint. concept code: Arthritis display: Arthritis definition: A disorder characterized by inflammation involving a joint. concept code: Ascites display: Ascites definition: A disorder characterized by accumulation of serous or hemorrhagic fluid in the peritoneal cavity. concept code: Aspartate aminotransferase increased display: Aspartate aminotransferase increased definition: A finding based on laboratory test results that indicate an increase in the level of aspartate aminotransferase (AST or SGOT) in a blood specimen. concept code: Aspiration display: Aspiration definition: A disorder characterized by inhalation of solids or liquids into the lungs. concept code: Asystole display: Asystole definition: A disorder characterized by a dysrhythmia without cardiac electrical activity. Typically, this is accompanied by cessation of the pumping function of the heart. concept code: Ataxia display: Ataxia definition: A disorder characterized by lack of coordination of muscle movements resulting in the impairment or inability to perform voluntary activities. concept code: Atelectasis display: Atelectasis definition: A disorder characterized by the collapse of part or the entire lung. concept code: Atrial fibrillation display: Atrial fibrillation definition: A disorder characterized by a dysrhythmia without discernible P waves and an irregular ventricular response due to multiple reentry circuits. The rhythm disturbance originates above the ventricles. concept code: Atrial flutter display: Atrial flutter definition: A disorder characterized by a dysrhythmia with organized rhythmic atrial contractions with a rate of 200-300 beats per minute. The rhythm disturbance originates in the atria. concept code: Atrioventricular block complete display: Atrioventricular block complete definition: A disorder characterized by a dysrhythmia with complete failure of atrial electrical impulse conduction through the AV node to the ventricles. concept code: Atrioventricular block first degree display: Atrioventricular block first degree definition: A disorder characterized by a dysrhythmia with a delay in the time required for the conduction of an electrical impulse through the atrioventricular (AV) node beyond 0.2 seconds; prolongation of the PR interval greater than 200 milliseconds. concept code: Autoimmune disorder display: Autoimmune disorder definition: A disorder resulting from loss of function or tissue destruction of an organ or multiple organs, arising from humoral or cellular immune responses of the individual to his own tissue constituents. concept code: Avascular necrosis display: Avascular necrosis definition: A disorder characterized by necrotic changes in the bone tissue due to interruption of blood supply. Most often affecting the epiphysis of the long bones, the necrotic changes result in the collapse and the destruction of the bone structure. concept code: Azoospermia display: Azoospermia definition: A disorder characterized by laboratory test results that indicate complete absence of spermatozoa in the semen. concept code: Back pain display: Back pain definition: A disorder characterized by marked discomfort sensation in the back region. concept code: Bile duct stenosis display: Bile duct stenosis definition: A disorder characterized by a narrowing of the lumen of the bile duct. concept code: Biliary anastomotic leak display: Biliary anastomotic leak definition: A finding of leakage of bile due to breakdown of a biliary anastomosis (surgical connection of two separate anatomic structures). concept code: Biliary fistula display: Biliary fistula definition: A disorder characterized by an abnormal communication between the bile ducts and another organ or anatomic site. concept code: Biliary tract infection display: Biliary tract infection definition: A disorder characterized by an infectious process involving the biliary tract. concept code: Bladder anastomotic leak display: Bladder anastomotic leak definition: A finding of leakage of urine due to breakdown of a bladder anastomosis (surgical connection of two separate anatomic structures). concept code: Bladder infection display: Bladder infection definition: A disorder characterized by an infectious process involving the bladder. concept code: Bladder perforation display: Bladder perforation definition: A disorder characterized by a rupture in the bladder wall. concept code: Bladder spasm display: Bladder spasm definition: A disorder characterized by a sudden and involuntary contraction of the bladder wall. concept code: Bloating display: Bloating definition: A disorder characterized by subject-reported feeling of uncomfortable fullness of the abdomen. concept code: Blood and lymphatic system disorders - Other, Specify display: Blood and lymphatic system disorders - Other, specify definition: No Value Exists concept code: Blood antidiuretic hormone abnormal display: Blood antidiuretic hormone abnormal definition: A finding based on laboratory test results that indicate abnormal levels of antidiuretic hormone in the blood specimen. concept code: Blood bilirubin increased display: Blood bilirubin increased definition: A finding based on laboratory test results that indicate an abnormally high level of bilirubin in the blood. Excess bilirubin is associated with jaundice. concept code: Blood corticotrophin decreased display: Blood corticotrophin decreased definition: A finding based on laboratory test results that indicate an decrease in levels of corticotrophin in a blood specimen. concept code: Blood gonadotrophin abnormal display: Blood gonadotrophin abnormal definition: A finding based on laboratory test results that indicate abnormal levels of gonadotrophin hormone in a blood specimen. concept code: Blood prolactin abnormal display: Blood prolactin abnormal definition: A finding based on laboratory test results that indicate abnormal levels of prolactin hormone in a blood specimen. concept code: Blurred vision display: Blurred vision definition: A disorder characterized by visual perception of unclear or fuzzy images. concept code: Body odor display: Body odor definition: A disorder characterized by an abnormal body smell resulting from the growth of bacteria on the body. concept code: Bone infection display: Bone infection definition: A disorder characterized by an infectious process involving the bones. concept code: Bone marrow hypocellular display: Bone marrow hypocellular definition: A disorder characterized by the inability of the bone marrow to produce hematopoietic elements. concept code: Bone pain display: Bone pain definition: A disorder characterized by marked discomfort sensation in the bones. concept code: Brachial plexopathy display: Brachial plexopathy definition: A disorder characterized by regional paresthesia of the brachial plexus, marked discomfort and muscle weakness, and limited movement in the arm or hand. concept code: Breast atrophy display: Breast atrophy definition: A disorder characterized by underdevelopment of the breast. concept code: Breast infection display: Breast infection definition: A disorder characterized by an infectious process involving the breast. concept code: Breast pain display: Breast pain definition: A disorder characterized by marked discomfort sensation in the breast region. concept code: Bronchial fistula display: Bronchial fistula definition: A disorder characterized by an abnormal communication between the bronchus and another organ or anatomic site. concept code: Bronchial infection display: Bronchial infection definition: A disorder characterized by an infectious process involving the bronchi. concept code: Bronchial obstruction display: Bronchial obstruction definition: A disorder characterized by blockage of a bronchus passage, most often by bronchial secretions and exudates. concept code: Bronchial stricture display: Bronchial stricture definition: A disorder characterized by a narrowing of the bronchial tube. concept code: Bronchopleural fistula display: Bronchopleural fistula definition: A disorder characterized by an abnormal communication between a bronchus and the pleural cavity. concept code: Bronchopulmonary hemorrhage display: Bronchopulmonary hemorrhage definition: A disorder characterized by bleeding from the bronchial wall and/or lung parenchyma. concept code: Bronchospasm display: Bronchospasm definition: A disorder characterized by a sudden contraction of the smooth muscles of the bronchial wall. concept code: Bruising display: Bruising definition: A finding of injury of the soft tissues or bone characterized by leakage of blood into surrounding tissues. concept code: Bullous dermatitis display: Bullous dermatitis definition: A disorder characterized by inflammation of the skin characterized by the presence of bullae which are filled with fluid. concept code: Burn display: Burn definition: A finding of impaired integrity to the anatomic site of an adverse thermal reaction. Burns can be caused by exposure to chemicals, direct heat, electricity, flames and radiation. The extent of damage depends on the length and intensity of exposure and time until provision of treatment. concept code: Buttock pain display: Buttock pain definition: A disorder characterized by marked discomfort sensation in the buttocks. concept code: Capillary leak syndrome display: Capillary leak syndrome definition: A disorder characterized by leakage of intravascular fluids into the extravascular space. This syndrome is observed in patients who demonstrate a state of generalized leaky capillaries following shock syndromes, low-flow states, ischemia-reperfusion injuries, toxemias, medications, or poisoning. It can lead to generalized edema and multiple organ failure. concept code: Carbon monoxide diffusing capacity decreased display: Carbon monoxide diffusing capacity decreased definition: A finding based on lung function test results that indicate a decrease in the lung capacity to absorb carbon monoxide. concept code: Cardiac arrest display: Cardiac arrest definition: A disorder characterized by cessation of the pumping function of the heart. concept code: Cardiac disorders - Other, Specify display: Cardiac disorders - Other, specify definition: No Value Exists concept code: Cardiac troponin I increased display: Cardiac troponin I increased definition: A laboratory test result which indicates increased levels of cardiac troponin I in a biological specimen. concept code: Cardiac troponin T increased display: Cardiac troponin T increased definition: A laboratory test result which indicates increased levels of cardiac troponin T in a biological specimen. concept code: Cataract display: Cataract definition: A disorder characterized by partial or complete opacity of the crystalline lens of one or both eyes. This results in a decrease in visual acuity and eventual blindness if untreated. concept code: Catheter related infection display: Catheter related infection definition: A disorder characterized by an infectious process that arises secondary to catheter use. concept code: CD4 lymphocytes decreased display: CD4 lymphocytes decreased definition: A finding based on laboratory test results that indicate an decrease in levels of CD4 lymphocytes in a blood specimen. concept code: Cecal hemorrhage display: Cecal hemorrhage definition: A disorder characterized by bleeding from the cecum. concept code: Cecal infection display: Cecal infection definition: A disorder characterized by an infectious process involving the cecum. concept code: Central nervous system necrosis display: Central nervous system necrosis definition: A disorder characterized by a necrotic process occurring in the brain and/or spinal cord. concept code: Cerebrospinal fluid leakage display: Cerebrospinal fluid leakage definition: A disorder characterized by loss of cerebrospinal fluid into the surrounding tissues. concept code: Cervicitis infection display: Cervicitis infection definition: A disorder characterized by an infectious process involving the uterine cervix. concept code: Cheilitis display: Cheilitis definition: A disorder characterized by inflammation of the lip. concept code: Chest pain - cardiac display: Chest pain - cardiac definition: A disorder characterized by substernal discomfort due to insufficient myocardial oxygenation. concept code: Chest wall pain display: Chest wall pain definition: A disorder characterized by marked discomfort sensation in the chest wall region. concept code: Chills display: Chills definition: A disorder characterized by a sensation of cold that often marks a physiologic response to sweating after a fever. concept code: Cholecystitis display: Cholecystitis definition: A disorder characterized by inflammation involving the gallbladder. It may be associated with the presence of gallstones. concept code: Cholesterol high display: Cholesterol high definition: A finding based on laboratory test results that indicate higher than normal levels of cholesterol in a blood specimen. concept code: Chronic kidney disease display: Chronic kidney disease definition: A disorder characterized by gradual and usually permanent loss of kidney function resulting in renal failure. concept code: Chylothorax display: Chylothorax definition: A disorder characterized by milky pleural effusion (abnormal collection of fluid) resulting from accumulation of lymph fluid in the pleural cavity. concept code: Cognitive disturbance display: Cognitive disturbance definition: A disorder characterized by a conspicuous change in cognitive function. concept code: Colitis display: Colitis definition: A disorder characterized by inflammation of the colon. concept code: Colonic fistula display: Colonic fistula definition: A disorder characterized by an abnormal communication between the large intestine and another organ or anatomic site. concept code: Colonic hemorrhage display: Colonic hemorrhage definition: A disorder characterized by bleeding from the colon. concept code: Colonic obstruction display: Colonic obstruction definition: A disorder characterized by blockage of the normal flow of the intestinal contents in the colon. concept code: Colonic perforation display: Colonic perforation definition: A disorder characterized by a rupture in the colonic wall. concept code: Colonic stenosis display: Colonic stenosis definition: A disorder characterized by a narrowing of the lumen of the colon. concept code: Colonic ulcer display: Colonic ulcer definition: A disorder characterized by a circumscribed, inflammatory and necrotic erosive lesion on the mucosal surface of the colon. concept code: Concentration impairment display: Concentration impairment definition: A disorder characterized by a deterioration in the ability to concentrate. concept code: Conduction disorder display: Conduction disorder definition: A disorder characterized by pathological irregularities in the cardiac conduction system. concept code: Confusion display: Confusion definition: A disorder characterized by a lack of clear and orderly thought and behavior. concept code: Congenital, familial and genetic disorders - Other, Specify display: Congenital, familial and genetic disorders - Other, specify definition: No Value Exists concept code: Conjunctivitis display: Conjunctivitis definition: A disorder characterized by inflammation, swelling and redness to the conjunctiva of the eye. concept code: Conjunctivitis infective display: Conjunctivitis infective definition: A disorder characterized by an infectious process involving the conjunctiva. Clinical manifestations include pink or red color in the eyes. concept code: Constipation display: Constipation definition: A disorder characterized by irregular and infrequent or difficult evacuation of the bowels. concept code: Constrictive pericarditis display: Constrictive pericarditis definition: A disorder characterized by a thickened and fibrotic pericardial sac; these fibrotic changes impede normal myocardial function by restricting myocardial muscle action. concept code: Corneal infection display: Corneal infection definition: A disorder characterized by an infectious process involving the cornea. concept code: Corneal ulcer display: Corneal ulcer definition: A disorder characterized by an area of epithelial tissue loss on the surface of the cornea. It is associated with inflammatory cells in the cornea and anterior chamber. concept code: Cough display: Cough definition: A disorder characterized by sudden, often repetitive, spasmodic contraction of the thoracic cavity, resulting in violent release of air from the lungs and usually accompanied by a distinctive sound. concept code: CPK increased display: CPK increased definition: A finding based on laboratory test results that indicate an increase in levels of creatine phosphokinase in a blood specimen. concept code: Cranial nerve infection display: Cranial nerve infection definition: A disorder characterized by an infectious process involving a cranial nerve. concept code: Creatinine increased display: Creatinine increased definition: A finding based on laboratory test results that indicate increased levels of creatinine in a biological specimen. concept code: Cushingoid display: Cushingoid definition: A disorder characterized by signs and symptoms that resemble Cushing's disease or syndrome: buffalo hump obesity, striations, adiposity, hypertension, diabetes, and osteoporosis, usually due to exogenous corticosteroids. concept code: Cystitis noninfective display: Cystitis noninfective definition: A disorder characterized by inflammation of the bladder which is not caused by an infection of the urinary tract. concept code: Cytokine release syndrome display: Cytokine release syndrome definition: A disorder characterized by nausea, headache, tachycardia, hypotension, rash, and shortness of breath; it is caused by the release of cytokines from the cells. concept code: Death neonatal display: Death neonatal definition: A disorder characterized by cessation of life occurring during the first 28 days of life. concept code: Death NOS display: Death NOS definition: A cessation of life that cannot be attributed to a CTCAE term associated with Grade 5. concept code: Dehydration display: Dehydration definition: A disorder characterized by excessive loss of water from the body. It is usually caused by severe diarrhea, vomiting or diaphoresis. concept code: Delayed orgasm display: Delayed orgasm definition: A disorder characterized by sexual dysfunction characterized by a delay in climax. concept code: Delayed puberty display: Delayed puberty definition: A disorder characterized by unusually late sexual maturity. concept code: Delirium display: Delirium definition: A disorder characterized by the acute and sudden development of confusion, illusions, movement changes, inattentiveness, agitation, and hallucinations. Usually, it is a reversible condition. concept code: Delusions display: Delusions definition: A disorder characterized by false personal beliefs held contrary to reality, despite contradictory evidence and common sense. concept code: Dental caries display: Dental caries definition: A disorder characterized by the decay of a tooth, in which it becomes softened, discolored and/or porous. concept code: Depressed level of consciousness display: Depressed level of consciousness definition: A disorder characterized by a decrease in ability to perceive and respond. concept code: Depression display: Depression definition: A disorder characterized by melancholic feelings of grief or unhappiness. concept code: Dermatitis radiation display: Dermatitis radiation definition: A finding of cutaneous inflammatory reaction occurring as a result of exposure to biologically effective levels of ionizing radiation. concept code: Device related infection display: Device related infection definition: A disorder characterized by an infectious process involving the use of a medical device. concept code: Diarrhea display: Diarrhea definition: A disorder characterized by frequent and watery bowel movements. concept code: Disseminated intravascular coagulation display: Disseminated intravascular coagulation definition: A disorder characterized by systemic pathological activation of blood clotting mechanisms which results in clot formation throughout the body. There is an increase in the risk of hemorrhage as the body is depleted of platelets and coagulation factors. concept code: Dizziness display: Dizziness definition: A disorder characterized by a disturbing sensation of lightheadedness, unsteadiness, giddiness, spinning or rocking. concept code: Dry eye display: Dry eye definition: A disorder characterized by dryness of the cornea and conjunctiva. concept code: Dry mouth display: Dry mouth definition: A disorder characterized by reduced salivary flow in the oral cavity. concept code: Dry skin display: Dry skin definition: A disorder characterized by flaky and dull skin; the pores are generally fine, the texture is a papery thin texture. concept code: Duodenal fistula display: Duodenal fistula definition: A disorder characterized by an abnormal communication between the duodenum and another organ or anatomic site. concept code: Duodenal hemorrhage display: Duodenal hemorrhage definition: A disorder characterized by bleeding from the duodenum. concept code: Duodenal infection display: Duodenal infection definition: A disorder characterized by an infectious process involving the duodenum. concept code: Duodenal obstruction display: Duodenal obstruction definition: A disorder characterized by blockage of the normal flow of stomach contents through the duodenum. concept code: Duodenal perforation display: Duodenal perforation definition: A disorder characterized by a rupture in the duodenal wall. concept code: Duodenal stenosis display: Duodenal stenosis definition: A disorder characterized by a narrowing of the lumen of the duodenum. concept code: Duodenal ulcer display: Duodenal ulcer definition: A disorder characterized by a circumscribed, inflammatory and necrotic erosive lesion on the mucosal surface of the duodenal wall. concept code: Dysarthria display: Dysarthria definition: A disorder characterized by slow and slurred speech resulting from an inability to coordinate the muscles used in speech. concept code: Dysesthesia display: Dysesthesia definition: A disorder characterized by distortion of sensory perception, resulting in an abnormal and unpleasant sensation. concept code: Dysgeusia display: Dysgeusia definition: A disorder characterized by abnormal sensual experience with the taste of foodstuffs; it can be related to a decrease in the sense of smell. concept code: Dysmenorrhea display: Dysmenorrhea definition: A disorder characterized by abnormally painful abdominal cramps during menses. concept code: Dyspareunia display: Dyspareunia definition: A disorder characterized by painful or difficult coitus. concept code: Dyspepsia display: Dyspepsia definition: A disorder characterized by an uncomfortable, often painful feeling in the stomach, resulting from impaired digestion. Symptoms include burning stomach, bloating, heartburn, nausea and vomiting. concept code: Dysphagia display: Dysphagia definition: A disorder characterized by difficulty in swallowing. concept code: Dysphasia display: Dysphasia definition: A disorder characterized by impairment of verbal communication skills, often resulting from brain damage. concept code: Dyspnea display: Dyspnea definition: A disorder characterized by an uncomfortable sensation of difficulty breathing. concept code: Ear and labyrinth disorders - Other, Specify display: Ear and labyrinth disorders - Other, specify definition: No Value Exists concept code: Ear pain display: Ear pain definition: A disorder characterized by a sensation of marked discomfort in the ear. concept code: Edema cerebral display: Edema cerebral definition: A disorder characterized by swelling due to an excessive accumulation of fluid in the brain. concept code: Edema face display: Edema face definition: A disorder characterized by swelling due to excessive fluid accumulation in facial tissues. concept code: Edema limbs display: Edema limbs definition: A disorder characterized by swelling due to excessive fluid accumulation in the upper or lower extremities. concept code: Edema trunk display: Edema trunk definition: A disorder characterized by swelling due to excessive fluid accumulation in the trunk area. concept code: Ejaculation disorder display: Ejaculation disorder definition: A disorder characterized by problems related to ejaculation. This category includes premature, delayed, retrograde and painful ejaculation. concept code: Ejection fraction decreased display: Ejection fraction decreased definition: The percentage computed when the amount of blood ejected during a ventricular contraction of the heart is compared to the amount that was present prior to the contraction. concept code: Electrocardiogram QT corrected interval prolonged display: Electrocardiogram QT corrected interval prolonged definition: A finding of a cardiac dysrhythmia characterized by an abnormally long corrected QT interval. concept code: Encephalitis infection display: Encephalitis infection definition: A disorder characterized by an infectious process involving the brain tissue. concept code: Encephalomyelitis infection display: Encephalomyelitis infection definition: A disorder characterized by an infectious process involving the brain and spinal cord tissues. concept code: Encephalopathy display: Encephalopathy definition: A disorder characterized by a pathologic process involving the brain. concept code: Endocarditis infective display: Endocarditis infective definition: A disorder characterized by an infectious process involving the endocardial layer of the heart. concept code: Endocrine disorders - Other, Specify display: Endocrine disorders - Other, specify definition: No Value Exists concept code: Endophthalmitis display: Endophthalmitis definition: A disorder characterized by an infectious process involving the internal structures of the eye. concept code: Enterocolitis display: Enterocolitis definition: A disorder characterized by inflammation of the small and large intestines. concept code: Enterocolitis infectious display: Enterocolitis infectious definition: A disorder characterized by an infectious process involving the small and large intestines. concept code: Enterovesical fistula display: Enterovesical fistula definition: A disorder characterized by an abnormal communication between the urinary bladder and the intestine. concept code: Epistaxis display: Epistaxis definition: A disorder characterized by bleeding from the nose. concept code: Erectile dysfunction display: Erectile dysfunction definition: A disorder characterized by the persistent or recurrent inability to achieve or to maintain an erection during sexual activity. concept code: Erythema multiforme display: Erythema multiforme definition: A disorder characterized by target lesions (a pink-red ring around a pale center). concept code: Erythroderma display: Erythroderma definition: A disorder characterized by generalized inflammatory erythema and exfoliation. The inflammatory process involves > 90% of the body surface area. concept code: Esophageal anastomotic leak display: Esophageal anastomotic leak definition: A finding of leakage due to breakdown of an esophageal anastomosis (surgical connection of two separate anatomic structures). concept code: Esophageal fistula display: Esophageal fistula definition: A disorder characterized by an abnormal communication between the esophagus and another organ or anatomic site. concept code: Esophageal hemorrhage display: Esophageal hemorrhage definition: A disorder characterized by bleeding from the esophagus. concept code: Esophageal infection display: Esophageal infection definition: A disorder characterized by an infectious process involving the esophagus. concept code: Esophageal necrosis display: Esophageal necrosis definition: A disorder characterized by a necrotic process occurring in the esophageal wall. concept code: Esophageal obstruction display: Esophageal obstruction definition: A disorder characterized by blockage of the normal flow of the contents in the esophagus. concept code: Esophageal pain display: Esophageal pain definition: A disorder characterized by a sensation of marked discomfort in the esophageal region. concept code: Esophageal perforation display: Esophageal perforation definition: A disorder characterized by a rupture in the wall of the esophagus. concept code: Esophageal stenosis display: Esophageal stenosis definition: A disorder characterized by a narrowing of the lumen of the esophagus. concept code: Esophageal ulcer display: Esophageal ulcer definition: A disorder characterized by a circumscribed, inflammatory and necrotic erosive lesion on the mucosal surface of the esophageal wall. concept code: Esophageal varices hemorrhage display: Esophageal varices hemorrhage definition: A disorder characterized by bleeding from esophageal varices. concept code: Esophagitis display: Esophagitis definition: A disorder characterized by inflammation of the esophageal wall. concept code: Euphoria display: Euphoria definition: A disorder characterized by an exaggerated feeling of well-being which is disproportionate to events and stimuli. concept code: Exostosis display: Exostosis definition: A disorder characterized by non-neoplastic overgrowth of bone. concept code: External ear inflammation display: External ear inflammation definition: A disorder characterized by inflammation, swelling and redness to the outer ear and ear canal. concept code: External ear pain display: External ear pain definition: A disorder characterized by a sensation of marked discomfort in the external ear region. concept code: Extraocular muscle paresis display: Extraocular muscle paresis definition: A disorder characterized by incomplete paralysis of an extraocular muscle. concept code: Extrapyramidal disorder display: Extrapyramidal disorder definition: A disorder characterized by abnormal, repetitive, involuntary muscle movements, frenzied speech and extreme restlessness. concept code: Eye disorders - Other, Specify display: Eye disorders - Other, specify definition: No Value Exists concept code: Eye infection display: Eye infection definition: A disorder characterized by an infectious process involving the eye. concept code: Eye pain display: Eye pain definition: A disorder characterized by a sensation of marked discomfort in the eye. concept code: Eyelid function disorder display: Eyelid function disorder definition: A disorder characterized by impaired eyelid function. concept code: Facial muscle weakness display: Facial muscle weakness definition: A disorder characterized by a reduction in the strength of the facial muscles. concept code: Facial nerve disorder display: Facial nerve disorder definition: A disorder characterized by involvement of the facial nerve (seventh cranial nerve). concept code: Facial pain display: Facial pain definition: A disorder characterized by a sensation of marked discomfort in the face. concept code: Fall display: Fall definition: A finding of sudden movement downward, usually resulting in injury. concept code: Fallopian tube anastomotic leak display: Fallopian tube anastomotic leak definition: A finding of leakage due to breakdown of a fallopian tube anastomosis (surgical connection of two separate anatomic structures). concept code: Fallopian tube obstruction display: Fallopian tube obstruction definition: A disorder characterized by blockage of the normal flow of the contents in the fallopian tube. concept code: Fallopian tube perforation display: Fallopian tube perforation definition: A finding of rupture of the fallopian tube wall. concept code: Fallopian tube stenosis display: Fallopian tube stenosis definition: A disorder characterized by a narrowing of the fallopian tube lumen. concept code: Fat atrophy display: Fat atrophy definition: A disorder characterized by shrinking of adipose tissue. concept code: Fatigue display: Fatigue definition: A disorder characterized by a state of generalized weakness with a pronounced inability to summon sufficient energy to accomplish daily activities. concept code: Febrile neutropenia display: Febrile neutropenia definition: A disorder characterized by a decrease in neutrophils associated with fever. concept code: Fecal incontinence display: Fecal incontinence definition: A disorder characterized by inability to control the escape of stool from the rectum. concept code: Female genital tract fistula display: Female genital tract fistula definition: A disorder characterized by an abnormal communication between a female reproductive system organ and another organ or anatomic site. concept code: Feminization acquired display: Feminization acquired definition: A disorder characterized by the development of secondary female sex characteristics in males due to extrinsic factors. concept code: Fetal death display: Fetal death definition: A disorder characterized by death in utero; failure of the product of conception to show evidence of respiration, heartbeat, or definite movement of a voluntary muscle after expulsion from the uterus, without possibility of resuscitation. concept code: Fetal growth retardation display: Fetal growth retardation definition: A disorder characterized by inhibition of fetal growth resulting in the inability of the fetus to achieve its potential weight. concept code: Fever display: Fever definition: A disorder characterized by elevation of the body's temperature above the upper limit of normal. concept code: Fibrinogen decreased display: Fibrinogen decreased definition: A finding based on laboratory test results that indicate an decrease in levels of fibrinogen in a blood specimen. concept code: Fibrosis deep connective tissue display: Fibrosis deep connective tissue definition: A disorder characterized by fibrotic degeneration of the deep connective tissues. concept code: Flank pain display: Flank pain definition: A disorder characterized by marked discomfort sensation on the lateral side of the body in the region below the ribs and above the hip. concept code: Flashing lights display: Flashing lights definition: A disorder characterized by a sudden or brief burst of light. concept code: Flatulence display: Flatulence definition: A disorder characterized by a state of excessive gas in the alimentary canal. concept code: Floaters display: Floaters definition: A disorder characterized by an individual seeing spots before their eyes. The spots are shadows of opaque cell fragments in the vitreous humor or lens. concept code: Flu like symptoms display: Flu like symptoms definition: A disorder characterized by a group of symptoms similar to those observed in patients with the flu. It includes fever, chills, body aches, malaise, loss of appetite and dry cough. concept code: Flushing display: Flushing definition: A disorder characterized by episodic reddening of the face. concept code: Forced expiratory volume decreased display: Forced expiratory volume decreased definition: A finding based on test results that indicate a relative decrease in the fraction of the forced vital capacity that is exhaled in a specific number of seconds. concept code: Fracture display: Fracture definition: A finding of traumatic injury to the bone in which the continuity of the bone is broken. concept code: Gait disturbance display: Gait disturbance definition: A disorder characterized by walking difficulties. concept code: Gallbladder fistula display: Gallbladder fistula definition: A disorder characterized by an abnormal communication between the gallbladder and another organ or anatomic site. concept code: Gallbladder infection display: Gallbladder infection definition: A disorder characterized by an infectious process involving the gallbladder. concept code: Gallbladder necrosis display: Gallbladder necrosis definition: A disorder characterized by a necrotic process occurring in the gallbladder. concept code: Gallbladder obstruction display: Gallbladder obstruction definition: A disorder characterized by blockage of the normal flow of the contents of the gallbladder. concept code: Gallbladder pain display: Gallbladder pain definition: A disorder characterized by a sensation of marked discomfort in the gallbladder region. concept code: Gallbladder perforation display: Gallbladder perforation definition: A disorder characterized by a rupture in the gallbladder wall. concept code: Gastric anastomotic leak display: Gastric anastomotic leak definition: A finding of leakage due to breakdown of a gastric anastomosis (surgical connection of two separate anatomic structures). concept code: Gastric fistula display: Gastric fistula definition: A disorder characterized by an abnormal communication between the stomach and another organ or anatomic site. concept code: Gastric hemorrhage display: Gastric hemorrhage definition: A disorder characterized by bleeding from the gastric wall. concept code: Gastric necrosis display: Gastric necrosis definition: A disorder characterized by a necrotic process occurring in the gastric wall. concept code: Gastric perforation display: Gastric perforation definition: A disorder characterized by a rupture in the stomach wall. concept code: Gastric stenosis display: Gastric stenosis definition: A disorder characterized by a narrowing of the lumen of the stomach. concept code: Gastric ulcer display: Gastric ulcer definition: A disorder characterized by a circumscribed, inflammatory and necrotic erosive lesion on the mucosal surface of the stomach. concept code: Gastritis display: Gastritis definition: A disorder characterized by inflammation of the stomach. concept code: Gastroesophageal reflux disease display: Gastroesophageal reflux disease definition: A disorder characterized by reflux of the gastric and/or duodenal contents into the distal esophagus. It is chronic in nature and usually caused by incompetence of the lower esophageal sphincter, and may result in injury to the esophageal mucosal. Symptoms include heartburn and acid indigestion. concept code: Gastrointestinal anastomotic leak display: Gastrointestinal anastomotic leak definition: A finding of leakage due to breakdown of a gastrointestinal anastomosis (surgical connection of two separate anatomic structures). concept code: Gastrointestinal disorders - Other, Specify display: Gastrointestinal disorders - Other, specify definition: No Value Exists concept code: Gastrointestinal fistula display: Gastrointestinal fistula definition: A disorder characterized by an abnormal communication between any part of the gastrointestinal system and another organ or anatomic site. concept code: Gastrointestinal pain display: Gastrointestinal pain definition: A disorder characterized by a sensation of marked discomfort in the gastrointestinal region. concept code: Gastrointestinal stoma necrosis display: Gastrointestinal stoma necrosis definition: A finding of a necrotic process occurring in the gastrointestinal tract stoma. concept code: Gastroparesis display: Gastroparesis definition: A disorder characterized by an incomplete paralysis of the muscles of the stomach wall resulting in delayed emptying of the gastric contents into the small intestine. concept code: General disorders and administration site conditions - Other, Specify display: General disorders and administration site conditions - Other, specify definition: No Value Exists concept code: Generalized muscle weakness display: Generalized muscle weakness definition: A disorder characterized by a reduction in the strength of muscles in multiple anatomic sites. concept code: Genital edema display: Genital edema definition: A disorder characterized by swelling due to an excessive accumulation of fluid in the genitals. concept code: GGT increased display: GGT increased definition: A finding based on laboratory test results that indicate higher than normal levels of the enzyme gamma-glutamyltransferase in the blood specimen. GGT (gamma-glutamyltransferase ) catalyzes the transfer of a gamma glutamyl group from a gamma glutamyl peptide to another peptide, amino acids or water. concept code: Gingival pain display: Gingival pain definition: A disorder characterized by a sensation of marked discomfort in the gingival region. concept code: Glaucoma display: Glaucoma definition: A disorder characterized by an increase in pressure in the eyeball due to obstruction of the aqueous humor outflow. concept code: Glossopharyngeal nerve disorder display: Glossopharyngeal nerve disorder definition: A disorder characterized by involvement of the glossopharyngeal nerve (ninth cranial nerve). concept code: Glucose intolerance display: Glucose intolerance definition: A disorder characterized by an inability to properly metabolize glucose. concept code: Growth accelerated display: Growth accelerated definition: A disorder characterized by greater growth than expected for age. concept code: Growth hormone abnormal display: Growth hormone abnormal definition: A finding based on laboratory test results that indicate abnormal levels of growth hormone in a biological specimen. concept code: Growth suppression display: Growth suppression definition: A disorder characterized by of stature that is smaller than normal as expected for age. concept code: Gum infection display: Gum infection definition: A disorder characterized by an infectious process involving the gums. concept code: Gynecomastia display: Gynecomastia definition: A disorder characterized by excessive development of the breasts in males. concept code: Hallucinations display: Hallucinations definition: A disorder characterized by a false sensory perception in the absence of an external stimulus. concept code: Haptoglobin decreased display: Haptoglobin decreased definition: A finding based on laboratory test results that indicate an decrease in levels of haptoglobin in a blood specimen. concept code: Head soft tissue necrosis display: Head soft tissue necrosis definition: A disorder characterized by a necrotic process occurring in the soft tissues of the head. concept code: Headache display: Headache definition: A disorder characterized by a sensation of marked discomfort in various parts of the head, not confined to the area of distribution of any nerve. concept code: Hearing impaired display: Hearing impaired definition: A disorder characterized by partial or complete loss of the ability to detect or understand sounds resulting from damage to ear structures. concept code: Heart failure display: Heart failure definition: A disorder characterized by the inability of the heart to pump blood at an adequate volume to meet tissue metabolic requirements, or, the ability to do so only at an elevation in the filling pressure. concept code: Hematoma display: Hematoma definition: A disorder characterized by a localized collection of blood, usually clotted, in an organ, space, or tissue, due to a break in the wall of a blood vessel. concept code: Hematosalpinx display: Hematosalpinx definition: A disorder characterized by the presence of blood in a fallopian tube. concept code: Hematuria display: Hematuria definition: A disorder characterized by laboratory test results that indicate blood in the urine. concept code: Hemoglobin increased display: Hemoglobin increased definition: A finding based on laboratory test results that indicate increased levels of hemoglobin in a biological specimen. concept code: Hemoglobinuria display: Hemoglobinuria definition: A disorder characterized by laboratory test results that indicate the presence of free hemoglobin in the urine. concept code: Hemolysis display: Hemolysis definition: A disorder characterized by laboratory test results that indicate widespread erythrocyte cell membrane destruction. concept code: Hemolytic uremic syndrome display: Hemolytic uremic syndrome definition: A disorder characterized by a form of thrombotic microangiopathy with renal failure, hemolytic anemia, and severe thrombocytopenia. concept code: Hemorrhoidal hemorrhage display: Hemorrhoidal hemorrhage definition: A disorder characterized by bleeding from the hemorrhoids. concept code: Hemorrhoids display: Hemorrhoids definition: A disorder characterized by the presence of dilated veins in the rectum and surrounding area. concept code: Hepatic failure display: Hepatic failure definition: A disorder characterized by the inability of the liver to metabolize chemicals in the body. Laboratory test results reveal abnormal plasma levels of ammonia, bilirubin, lactic dehydrogenase, and alkaline phosphatase. concept code: Hepatic hemorrhage display: Hepatic hemorrhage definition: A disorder characterized by bleeding from the liver. concept code: Hepatic infection display: Hepatic infection definition: A disorder characterized by an infectious process involving the liver. concept code: Hepatic necrosis display: Hepatic necrosis definition: A disorder characterized by a necrotic process occurring in the hepatic parenchyma. concept code: Hepatic pain display: Hepatic pain definition: A disorder characterized by a sensation of marked discomfort in the liver region. concept code: Hepatitis viral display: Hepatitis viral definition: A disorder characterized by a viral pathologic process involving the liver parenchyma. concept code: Hepatobiliary disorders - Other, Specify display: Hepatobiliary disorders - Other, specify definition: No Value Exists concept code: Hiccups display: Hiccups definition: A disorder characterized by repeated gulp sounds that result from an involuntary opening and closing of the glottis. This is attributed to a spasm of the diaphragm. concept code: Hip fracture display: Hip fracture definition: A finding of traumatic injury to the hip in which the continuity of either the femoral head, femoral neck, intertrochanteric or subtrochanteric regions is broken. concept code: Hirsutism display: Hirsutism definition: A disorder characterized by the presence of excess hair growth in women in anatomic sites where growth is considered to be a secondary male characteristic and under androgen control (beard, moustache, chest, abdomen) concept code: Hoarseness display: Hoarseness definition: A disorder characterized by harsh and raspy voice arising from or spreading to the larynx. concept code: Hot flashes display: Hot flashes definition: A disorder characterized by an uncomfortable and temporary sensation of intense body warmth, flushing, sometimes accompanied by sweating upon cooling. concept code: Hydrocephalus display: Hydrocephalus definition: A disorder characterized by an abnormal increase of cerebrospinal fluid in the ventricles of the brain. concept code: Hypercalcemia display: Hypercalcemia definition: A disorder characterized by laboratory test results that indicate an elevation in the concentration of calcium in blood. concept code: Hyperglycemia display: Hyperglycemia definition: A disorder characterized by laboratory test results that indicate an elevation in the concentration of blood sugar. It is usually an indication of diabetes mellitus or glucose intolerance. concept code: Hyperhidrosis display: Hyperhidrosis definition: A disorder characterized by excessive perspiration. concept code: Hyperkalemia display: Hyperkalemia definition: A disorder characterized by laboratory test results that indicate an elevation in the concentration of potassium in the blood; associated with kidney failure or sometimes with the use of diuretic drugs. concept code: Hypermagnesemia display: Hypermagnesemia definition: A disorder characterized by laboratory test results that indicate an elevation in the concentration of magnesium in the blood. concept code: Hypernatremia display: Hypernatremia definition: A disorder characterized by laboratory test results that indicate an elevation in the concentration of sodium in the blood. concept code: Hyperparathyroidism display: Hyperparathyroidism definition: A disorder characterized by an increase in production of parathyroid hormone by the parathyroid glands. This results in hypercalcemia (abnormally high levels of calcium in the blood). concept code: Hypersomnia display: Hypersomnia definition: A disorder characterized by characterized by excessive sleepiness during the daytime. concept code: Hypertension display: Hypertension definition: A disorder characterized by a pathological increase in blood pressure; a repeatedly elevation in the blood pressure exceeding 140 over 90 mm Hg. concept code: Hyperthyroidism display: Hyperthyroidism definition: A disorder characterized by excessive levels of thyroid hormone in the body. Common causes include an overactive thyroid gland or thyroid hormone overdose. concept code: Hypertrichosis display: Hypertrichosis definition: A disorder characterized by hair density or length beyond the accepted limits of normal in a particular body region, for a particular age or race. concept code: Hypertriglyceridemia display: Hypertriglyceridemia definition: A disorder characterized by laboratory test results that indicate an elevation in the concentration of triglyceride concentration in the blood. concept code: Hyperuricemia display: Hyperuricemia definition: A disorder characterized by laboratory test results that indicate an elevation in the concentration of uric acid. concept code: Hypoalbuminemia display: Hypoalbuminemia definition: A disorder characterized by laboratory test results that indicate a low concentration of albumin in the blood. concept code: Hypocalcemia display: Hypocalcemia definition: A disorder characterized by laboratory test results that indicate a low concentration of calcium in the blood. concept code: Hypoglossal nerve disorder display: Hypoglossal nerve disorder definition: A disorder characterized by involvement of the hypoglossal nerve (twelfth cranial nerve). concept code: Hypoglycemia display: Hypoglycemia definition: A disorder characterized by laboratory test results that indicate a low concentration of glucose in the blood. concept code: Hypohidrosis display: Hypohidrosis definition: A disorder characterized by reduced sweating. concept code: Hypokalemia display: Hypokalemia definition: A disorder characterized by laboratory test results that indicate a low concentration of potassium in the blood. concept code: Hypomagnesemia display: Hypomagnesemia definition: A disorder characterized by laboratory test results that indicate a low concentration of magnesium in the blood. concept code: Hyponatremia display: Hyponatremia definition: A disorder characterized by laboratory test results that indicate a low concentration of sodium in the blood. concept code: Hypoparathyroidism display: Hypoparathyroidism definition: A disorder characterized by a decrease in production of parathyroid hormone by the parathyroid glands. concept code: Hypophosphatemia display: Hypophosphatemia definition: A disorder characterized by laboratory test results that indicate a low concentration of phosphates in the blood. concept code: Hypotension display: Hypotension definition: A disorder characterized by a blood pressure that is below the normal expected for an individual in a given environment. concept code: Hypothermia display: Hypothermia definition: A disorder characterized by an abnormally low body temperature. Treatment is required when the body temperature is 35C (95F) or below. concept code: Hypothyroidism display: Hypothyroidism definition: A disorder characterized by a decrease in production of thyroid hormone by the thyroid gland. concept code: Hypoxia display: Hypoxia definition: A disorder characterized by a decrease in the level of oxygen in the body. concept code: Ileal fistula display: Ileal fistula definition: A disorder characterized by an abnormal communication between the ileum and another organ or anatomic site. concept code: Ileal hemorrhage display: Ileal hemorrhage definition: A disorder characterized by bleeding from the ileal wall. concept code: Ileal obstruction display: Ileal obstruction definition: A disorder characterized by blockage of the normal flow of the intestinal contents in the ileum. concept code: Ileal perforation display: Ileal perforation definition: A disorder characterized by a rupture in the ileal wall. concept code: Ileal stenosis display: Ileal stenosis definition: A disorder characterized by a narrowing of the lumen of the ileum. concept code: Ileal ulcer display: Ileal ulcer definition: A disorder characterized by a circumscribed, inflammatory and necrotic erosive lesion on the mucosal surface of the ileum. concept code: Ileus display: Ileus definition: A disorder characterized by failure of the ileum to transport intestinal contents. concept code: Immune system disorders - Other, Specify display: Immune system disorders - Other, specify definition: No Value Exists concept code: Infections and infestations - Other, Specify display: Infections and infestations - Other, specify definition: No Value Exists concept code: Infective myositis display: Infective myositis definition: A disorder characterized by an infectious process involving the skeletal muscles. concept code: Infusion related reaction display: Infusion related reaction definition: A disorder characterized by adverse reaction to the infusion of pharmacological or biological substances. concept code: Infusion site extravasation display: Infusion site extravasation definition: A disorder characterized by leakage of a pharmacologic or a biologic substance from the infusion site into the surrounding tissue. Signs and symptoms include induration, erythema, swelling, burning sensation and marked discomfort at the infusion site. concept code: Injection site reaction display: Injection site reaction definition: A disorder characterized by an intense adverse reaction (usually immunologic) developing at the site of an injection. concept code: Injury to carotid artery display: Injury to carotid artery definition: A finding of damage to the carotid artery. concept code: Injury to inferior vena cava display: Injury to inferior vena cava definition: A finding of damage to the inferior vena cava. concept code: Injury to jugular vein display: Injury to jugular vein definition: A finding of damage to the jugular vein. concept code: Injury to superior vena cava display: Injury to superior vena cava definition: A finding of damage to the superior vena cava. concept code: Injury, poisoning and procedural complications - Other, Specify display: Injury, poisoning and procedural complications - Other, specify definition: No Value Exists concept code: INR increased display: INR increased definition: A finding based on laboratory test results that indicate an increase in the ratio of the patient's prothrombin time to a control sample in the blood. concept code: Insomnia display: Insomnia definition: A disorder characterized by difficulty in falling asleep and/or remaining asleep. concept code: Intestinal stoma leak display: Intestinal stoma leak definition: A finding of leakage of contents from an intestinal stoma (surgically created opening on the surface of the body). concept code: Intestinal stoma obstruction display: Intestinal stoma obstruction definition: A finding of blockage of the normal flow of the contents of the intestinal stoma. concept code: Intestinal stoma site bleeding display: Intestinal stoma site bleeding definition: A finding of blood leakage from the intestinal stoma. concept code: Intra-abdominal hemorrhage display: Intra-abdominal hemorrhage definition: A disorder characterized by bleeding in the abdominal cavity. concept code: Intracranial hemorrhage display: Intracranial hemorrhage definition: A disorder characterized by bleeding from the cranium. concept code: Intraoperative arterial injury display: Intraoperative arterial injury definition: A finding of damage to an artery during a surgical procedure. concept code: Intraoperative breast injury display: Intraoperative breast injury definition: A finding of damage to the breast parenchyma during a surgical procedure. concept code: Intraoperative cardiac injury display: Intraoperative cardiac injury definition: A finding of damage to the heart during a surgical procedure. concept code: Intraoperative ear injury display: Intraoperative ear injury definition: A finding of damage to the ear during a surgical procedure. concept code: Intraoperative endocrine injury display: Intraoperative endocrine injury definition: A finding of damage to the endocrine gland during a surgical procedure. concept code: Intraoperative gastrointestinal injury display: Intraoperative gastrointestinal injury definition: A finding of damage to the gastrointestinal system during a surgical procedure. concept code: Intraoperative head and neck injury display: Intraoperative head and neck injury definition: A finding of damage to the head and neck during a surgical procedure. concept code: Intraoperative hemorrhage display: Intraoperative hemorrhage definition: A finding of uncontrolled bleeding during a surgical procedure. concept code: Intraoperative hepatobiliary injury display: Intraoperative hepatobiliary injury definition: A finding of damage to the hepatic parenchyma and/or biliary tract during a surgical procedure. concept code: Intraoperative musculoskeletal injury display: Intraoperative musculoskeletal injury definition: A finding of damage to the musculoskeletal system during a surgical procedure. concept code: Intraoperative neurological injury display: Intraoperative neurological injury definition: A finding of damage to the nervous system during a surgical procedure. concept code: Intraoperative ocular injury display: Intraoperative ocular injury definition: A finding of damage to the eye during a surgical procedure. concept code: Intraoperative renal injury display: Intraoperative renal injury definition: A finding of damage to the kidney during a surgical procedure. concept code: Intraoperative reproductive tract injury display: Intraoperative reproductive tract injury definition: A finding of damage to the reproductive organs during a surgical procedure. concept code: Intraoperative respiratory injury display: Intraoperative respiratory injury definition: A finding of damage to the respiratory system during a surgical procedure. concept code: Intraoperative skin injury display: Intraoperative skin injury definition: A finding of damage to the skin during a surgical procedure. concept code: Intraoperative splenic injury display: Intraoperative splenic injury definition: A finding of damage to the spleen during a surgical procedure. concept code: Intraoperative urinary injury display: Intraoperative urinary injury definition: A finding of damage to the urinary system during a surgical procedure. concept code: Intraoperative venous injury display: Intraoperative venous injury definition: A finding of damage to a vein during a surgical procedure. concept code: Investigations - Other, Specify display: Investigations - Other, specify definition: No Value Exists concept code: Iron overload display: Iron overload definition: A disorder characterized by accumulation of iron in the tissues. concept code: Irregular menstruation display: Irregular menstruation definition: A disorder characterized by irregular cycle or duration of menses. concept code: Irritability display: Irritability definition: A disorder characterized by an abnormal responsiveness to stimuli or physiological arousal; may be in response to pain, fright, a drug, an emotional situation or a medical condition. concept code: Ischemia cerebrovascular display: Ischemia cerebrovascular definition: A disorder characterized by a decrease or absence of blood supply to the brain caused by obstruction (thrombosis or embolism) of an artery resulting in neurological damage. concept code: IVth nerve disorder display: IVth nerve disorder definition: A disorder characterized by involvement of the trochlear nerve (fourth cranial nerve). concept code: Jejunal fistula display: Jejunal fistula definition: A disorder characterized by an abnormal communication between the jejunum and another organ or anatomic site. concept code: Jejunal hemorrhage display: Jejunal hemorrhage definition: A disorder characterized by bleeding from the jejunal wall. concept code: Jejunal obstruction display: Jejunal obstruction definition: A disorder characterized by blockage of the normal flow of the intestinal contents in the jejunum. concept code: Jejunal perforation display: Jejunal perforation definition: A disorder characterized by a rupture in the jejunal wall. concept code: Jejunal stenosis display: Jejunal stenosis definition: A disorder characterized by a narrowing of the lumen of the jejunum. concept code: Jejunal ulcer display: Jejunal ulcer definition: A disorder characterized by a circumscribed, inflammatory and necrotic erosive lesion on the mucosal surface of the jejunum. concept code: Joint effusion display: Joint effusion definition: A disorder characterized by excessive fluid in a joint, usually as a result of joint inflammation. concept code: Joint infection display: Joint infection definition: A disorder characterized by an infectious process involving a joint. concept code: Joint range of motion decreased display: Joint range of motion decreased definition: A disorder characterized by a decrease in joint flexibility of any joint. concept code: Joint range of motion decreased cervical spine display: Joint range of motion decreased cervical spine definition: A disorder characterized by a decrease in flexibility of a cervical spine joint. concept code: Joint range of motion decreased lumbar spine display: Joint range of motion decreased lumbar spine definition: A disorder characterized by a decrease in flexibility of a lumbar spine joint. concept code: Keratitis display: Keratitis definition: A disorder characterized by inflammation to the cornea of the eye. concept code: Kidney anastomotic leak display: Kidney anastomotic leak definition: A finding of leakage of urine due to breakdown of a kidney anastomosis (surgical connection of two separate anatomic structures). concept code: Kidney infection display: Kidney infection definition: A disorder characterized by an infectious process involving the kidney. concept code: Kyphosis display: Kyphosis definition: A disorder characterized by an abnormal increase in the curvature of the thoracic portion of the spine. concept code: Lactation disorder display: Lactation disorder definition: A disorder characterized by disturbances of milk secretion. It is not necessarily related to pregnancy that is observed in females and can be observed in males. concept code: Large intestinal anastomotic leak display: Large intestinal anastomotic leak definition: A finding of leakage due to breakdown of an anastomosis (surgical connection of two separate anatomic structures) in the large intestine. concept code: Laryngeal edema display: Laryngeal edema definition: A disorder characterized by swelling due to an excessive accumulation of fluid in the larynx. concept code: Laryngeal fistula display: Laryngeal fistula definition: A disorder characterized by an abnormal communication between the larynx and another organ or anatomic site. concept code: Laryngeal hemorrhage display: Laryngeal hemorrhage definition: A disorder characterized by bleeding from the larynx. concept code: Laryngeal inflammation display: Laryngeal inflammation definition: A disorder characterized by an inflammation involving the larynx. concept code: Laryngeal mucositis display: Laryngeal mucositis definition: A disorder characterized by an inflammation involving the mucous membrane of the larynx. concept code: Laryngeal obstruction display: Laryngeal obstruction definition: A disorder characterized by blockage of the laryngeal airway. concept code: Laryngeal stenosis display: Laryngeal stenosis definition: A disorder characterized by a narrowing of the laryngeal airway. concept code: Laryngitis display: Laryngitis definition: A disorder characterized by an inflammatory process involving the larynx. concept code: Laryngopharyngeal dysesthesia display: Laryngopharyngeal dysesthesia definition: A disorder characterized by an uncomfortable persistent sensation in the area of the laryngopharynx. concept code: Laryngospasm display: Laryngospasm definition: A disorder characterized by paroxysmal spasmodic muscular contraction of the vocal cords. concept code: Left ventricular systolic dysfunction display: Left ventricular systolic dysfunction definition: A disorder characterized by failure of the left ventricle to produce adequate output despite an increase in distending pressure and in end-diastolic volume. Clinical manifestations mayinclude dyspnea, orthopnea, and other signs and symptoms of pulmonary congestion and edema. concept code: Lethargy display: Lethargy definition: A disorder characterized by a decrease in consciousness characterized by mental and physical inertness. concept code: Leukemia secondary to oncology chemotherapy display: Leukemia secondary to oncology chemotherapy definition: A disorder characterized by leukemia arising as a result of the mutagenic effect of chemotherapy agents. concept code: Leukocytosis display: Leukocytosis definition: A disorder characterized by laboratory test results that indicate an increased number of white blood cells in the blood. concept code: Leukoencephalopathy display: Leukoencephalopathy definition: A disorder characterized by diffuse reactive astrocytosis with multiple areas of necrotic foci without inflammation. concept code: Libido decreased display: Libido decreased definition: A disorder characterized by a decrease in sexual desire. concept code: Libido increased display: Libido increased definition: A disorder characterized by an increase in sexual desire. concept code: Lip infection display: Lip infection definition: A disorder characterized by an infectious process involving the lips. concept code: Lip pain display: Lip pain definition: A disorder characterized by a sensation of marked discomfort of the lip. concept code: Lipase increased display: Lipase increased definition: A finding based on laboratory test results that indicate an increase in the level of lipase in a biological specimen. concept code: Lipohypertrophy display: Lipohypertrophy definition: A disorder characterized by hypertrophy of the subcutaneous adipose tissue at the site of multiple subcutaneous injections of insulin. concept code: Localized edema display: Localized edema definition: A disorder characterized by swelling due to excessive fluid accumulation at a specific anatomic site. concept code: Lordosis display: Lordosis definition: A disorder characterized by an abnormal increase in the curvature of the lumbar portion of the spine. concept code: Lower gastrointestinal hemorrhage display: Lower gastrointestinal hemorrhage definition: A disorder characterized by bleeding from the lower gastrointestinal tract (small intestine, large intestine, and anus). concept code: Lung infection display: Lung infection definition: A disorder characterized by an infectious process involving the lungs. concept code: Lymph gland infection display: Lymph gland infection definition: A disorder characterized by an infectious process involving the lymph nodes. concept code: Lymph leakage display: Lymph leakage definition: A disorder characterized by the loss of lymph fluid into the surrounding tissue or body cavity. concept code: Lymph node pain display: Lymph node pain definition: A disorder characterized by a sensation of marked discomfort in a lymph node. concept code: Lymphedema display: Lymphedema definition: A disorder characterized by excessive fluid collection in tissues that causes swelling. concept code: Lymphocele display: Lymphocele definition: A disorder characterized by a cystic lesion containing lymph. concept code: Lymphocyte count decreased display: Lymphocyte count decreased definition: A finding based on laboratory test results that indicate a decrease in number of lymphocytes in a blood specimen. concept code: Lymphocyte count increased display: Lymphocyte count increased definition: A finding based on laboratory test results that indicate an abnormal increase in the number of lymphocytes in the blood, effusions or bone marrow. concept code: Malabsorption display: Malabsorption definition: A disorder characterized by inadequate absorption of nutrients in the small intestine. Symptoms include abdominal marked discomfort, bloating and diarrhea. concept code: Malaise display: Malaise definition: A disorder characterized by a feeling of general discomfort or uneasiness, an out-of-sorts feeling. concept code: Mania display: Mania definition: A disorder characterized by excitement of psychotic proportions manifested by mental and physical hyperactivity, disorganization of behavior and elevation of mood. concept code: Mediastinal hemorrhage display: Mediastinal hemorrhage definition: A disorder characterized by bleeding from the mediastinum. concept code: Mediastinal infection display: Mediastinal infection definition: A disorder characterized by an infectious process involving the mediastinum. concept code: Memory impairment display: Memory impairment definition: A disorder characterized by a deterioration in memory function. concept code: Meningismus display: Meningismus definition: A disorder characterized by neck stiffness, headache, and photophobia resulting from irritation of the cerebral meninges. concept code: Meningitis display: Meningitis definition: A disorder characterized by acute inflammation of the meninges of the brain and/or spinal cord. concept code: Menopause display: Menopause definition: A disorder characterized by the permanent cessation of menses, usually defined by 12 consecutive months of amenorrhea in a woman over 45 years of age. concept code: Menorrhagia display: Menorrhagia definition: A disorder characterized by abnormally heavy vaginal bleeding during menses. concept code: Metabolism and nutrition disorders - Other, Specify display: Metabolism and nutrition disorders - Other, specify definition: No Value Exists concept code: Middle ear inflammation display: Middle ear inflammation definition: A disorder characterized by inflammation (physiologic response to irritation), swelling and redness to the middle ear. concept code: Mitral valve disease display: Mitral valve disease definition: A disorder characterized by a defect in mitral valve function or structure. concept code: Mobitz (type) II atrioventricular block display: Mobitz (type) II atrioventricular block definition: A disorder characterized by a dysrhythmia with relatively constant PR interval prior to the block of an atrial impulse. This is the result of intermittent failure of atrial electrical impulse conduction through the atrioventricular (AV) node to the ventricles. concept code: Mobitz type I display: Mobitz type I definition: A disorder characterized by a dysrhythmia with a progressively lengthening PR interval prior to the blocking of an atrial impulse. This is the result of intermittent failure of atrial electrical impulse conduction through the atrioventricular (AV) node to the ventricles. concept code: Movements involuntary display: Movements involuntary definition: A disorder characterized by uncontrolled and purposeless movements. concept code: Mucosal infection display: Mucosal infection definition: A disorder characterized by an infectious process involving a mucosal surface. concept code: Mucositis oral display: Mucositis oral definition: A disorder characterized by inflammation of the oral mucosal. concept code: Multi-organ failure display: Multi-organ failure definition: A disorder characterized by progressive deterioration of the lungs, liver, kidney and clotting mechanisms. concept code: Muscle weakness left-sided display: Muscle weakness left-sided definition: A disorder characterized by a reduction in the strength of the muscles on the left side of the body. concept code: Muscle weakness lower limb display: Muscle weakness lower limb definition: A disorder characterized by a reduction in the strength of the lower limb muscles. concept code: Muscle weakness right-sided display: Muscle weakness right-sided definition: A disorder characterized by a reduction in the strength of the muscles on the right side of the body. concept code: Muscle weakness trunk display: Muscle weakness trunk definition: A disorder characterized by a reduction in the strength of the trunk muscles. concept code: Muscle weakness upper limb display: Muscle weakness upper limb definition: A disorder characterized by a reduction in the strength of the upper limb muscles. concept code: Musculoskeletal and connective tissue disorders - Other, Specify display: Musculoskeletal and connective tissue disorder - Other, specify definition: No Value Exists concept code: Musculoskeletal deformity display: Musculoskeletal deformity definition: A disorder characterized by of a malformation of the musculoskeletal system. concept code: Myalgia display: Myalgia definition: A disorder characterized by marked discomfort sensation originating from a muscle or group of muscles. concept code: Myelitis display: Myelitis definition: A disorder characterized by inflammation involving the spinal cord. Symptoms include weakness, paresthesia, sensory loss, marked discomfort and incontinence. concept code: Myelodysplastic syndrome display: Myelodysplastic syndrome definition: A disorder characterized by insufficiently healthy hematapoietic cell production by the bone marrow. concept code: Myocardial infarction display: Myocardial infarction definition: A disorder characterized by gross necrosis of the myocardium; this is due to an interruption of blood supply to the area. concept code: Myocarditis display: Myocarditis definition: A disorder characterized by inflammation of the muscle tissue of the heart. concept code: Myositis display: Myositis definition: A disorder characterized by inflammation involving the skeletal muscles. concept code: Nail discoloration display: Nail discoloration definition: A disorder characterized by a change in the color of the nail plate. concept code: Nail infection display: Nail infection definition: A disorder characterized by an infectious process involving the nail. concept code: Nail loss display: Nail loss definition: A disorder characterized by loss of all or a portion of the nail. concept code: Nail ridging display: Nail ridging definition: A disorder characterized by vertical or horizontal ridges on the nails. concept code: Nasal congestion display: Nasal congestion definition: A disorder characterized by obstruction of the nasal passage due to mucosal edema. concept code: Nausea display: Nausea definition: A disorder characterized by a queasy sensation and/or the urge to vomit. concept code: Neck edema display: Neck edema definition: A disorder characterized by swelling due to an accumulation of excessive fluid in the neck. concept code: Neck pain display: Neck pain definition: A disorder characterized by marked discomfort sensation in the neck area. concept code: Neck soft tissue necrosis display: Neck soft tissue necrosis definition: A disorder characterized by a necrotic process occurring in the soft tissues of the neck. concept code: Neoplasms benign, malignant and unspecified (incl cysts and polyps) - Other, Specify display: Neoplasms benign, malignant and unspecified (incl cysts and polyps) - Other, specify definition: No Value Exists concept code: Nervous system disorders - Other, Specify display: Nervous system disorders - Other, specify definition: No Value Exists concept code: Neuralgia display: Neuralgia definition: A disorder characterized by intense painful sensation along a nerve or group of nerves. concept code: Neutrophil count decreased display: Neutrophil count decreased definition: A finding based on laboratory test results that indicate a decrease in number of neutrophils in a blood specimen. concept code: Night blindness display: Night blindness definition: A disorder characterized by an inability to see clearly in dim light. concept code: Nipple deformity display: Nipple deformity definition: A disorder characterized by a malformation of the nipple. concept code: Non-cardiac chest pain display: Non-cardiac chest pain definition: A disorder characterized by discomfort in the chest unrelated to a heart disorder. concept code: Nystagmus display: Nystagmus definition: A disorder characterized by involuntary movements of the eyeballs. concept code: Obesity display: Obesity definition: A disorder characterized by having a high amount of body fat. concept code: Obstruction gastric display: Obstruction gastric definition: A disorder characterized by blockage of the normal flow of the contents in the stomach. concept code: Oculomotor nerve disorder display: Oculomotor nerve disorder definition: A disorder characterized by involvement of the oculomotor nerve (third cranial nerve). concept code: Olfactory nerve disorder display: Olfactory nerve disorder definition: A disorder characterized by involvement of the olfactory nerve (first cranial nerve). concept code: Oligospermia display: Oligospermia definition: A disorder characterized by a decrease in the number of spermatozoa in the semen. concept code: Optic nerve disorder display: Optic nerve disorder definition: A disorder characterized by involvement of the optic nerve (second cranial nerve). concept code: Oral cavity fistula display: Oral cavity fistula definition: A disorder characterized by an abnormal communication between the oral cavity and another organ or anatomic site. concept code: Oral dysesthesia display: Oral dysesthesia definition: A disorder characterized by a burning or tingling sensation on the lips, tongue or entire mouth. concept code: Oral hemorrhage display: Oral hemorrhage definition: A disorder characterized by bleeding from the mouth. concept code: Oral pain display: Oral pain definition: A disorder characterized by a sensation of marked discomfort in the mouth, tongue or lips. concept code: Osteonecrosis of jaw display: Osteonecrosis of jaw definition: A disorder characterized by a necrotic process occurring in the bone of the mandible. concept code: Osteoporosis display: Osteoporosis definition: A disorder characterized by reduced bone mass, with a decrease in cortical thickness and in the number and size of the trabeculae of cancellous bone (but normal chemical composition), resulting in increased fracture incidence. concept code: Otitis externa display: Otitis externa definition: A disorder characterized by an infectious process involving the outer ear and ear canal. Contributory factors include excessive water exposure (swimmer's ear infection) and cuts in the ear canal. Symptoms include fullness, itching, swelling and marked discomfort in the ear and ear drainage. concept code: Otitis media display: Otitis media definition: A disorder characterized by an infectious process involving the middle ear. concept code: Ovarian hemorrhage display: Ovarian hemorrhage definition: A disorder characterized by bleeding from the ovary. concept code: Ovarian infection display: Ovarian infection definition: A disorder characterized by an infectious process involving the ovary. concept code: Ovarian rupture display: Ovarian rupture definition: A disorder characterized by tearing or disruption of the ovarian tissue. concept code: Ovulation pain display: Ovulation pain definition: A disorder characterized by marked discomfort sensation in one side of the abdomen between menstrual cycles, around the time of the discharge of the ovum from the ovarian follicle. concept code: Pain display: Pain definition: A disorder characterized by the sensation of marked discomfort, distress or agony. concept code: Pain in extremity display: Pain in extremity definition: A disorder characterized by marked discomfort sensation in the upper or lower extremities. concept code: Pain of skin display: Pain of skin definition: A disorder characterized by marked discomfort sensation in the skin. concept code: Palmar-plantar erythrodysesthesia syndrome display: Palmar-plantar erythrodysesthesia syndrome definition: A disorder characterized by redness, marked discomfort, swelling, and tingling in the palms of the hands or the soles of the feet. concept code: Palpitations display: Palpitations definition: A disorder characterized by an unpleasant sensation of irregular and/or forceful beating of the heart. concept code: Pancreas infection display: Pancreas infection definition: A disorder characterized by an infectious process involving the pancreas. concept code: Pancreatic anastomotic leak display: Pancreatic anastomotic leak definition: A finding of leakage due to breakdown of a pancreatic anastomosis (surgical connection of two separate anatomic structures). concept code: Pancreatic duct stenosis display: Pancreatic duct stenosis definition: A disorder characterized by a narrowing of the lumen of the pancreatic duct. concept code: Pancreatic enzymes decreased display: Pancreatic enzymes decreased definition: A finding based on laboratory test results that indicate an decrease in levels of pancreatic enzymes in a biological specimen. concept code: Pancreatic fistula display: Pancreatic fistula definition: A disorder characterized by an abnormal communication between the pancreas and another organ or anatomic site. concept code: Pancreatic hemorrhage display: Pancreatic hemorrhage definition: A disorder characterized by bleeding from the pancreas. concept code: Pancreatic necrosis display: Pancreatic necrosis definition: A disorder characterized by a necrotic process occurring in the pancreas. concept code: Pancreatitis display: Pancreatitis definition: A disorder characterized by inflammation of the pancreas. concept code: Papilledema display: Papilledema definition: A disorder characterized by swelling around the optic disc. concept code: Papulopustular rash display: Papulopustular rash definition: A disorder characterized by an eruption consisting of papules (a small, raised pimple) and pustules (a small pus filled blister), typically appearing in face, scalp, and upper chest and back Unlike acne, this rash does not present with whiteheads or blackheads, and can be symptomatic, with itchy or tender lesions. concept code: Paresthesia display: Paresthesia definition: A disorder characterized by functional disturbances of sensory neurons resulting in abnormal cutaneous sensations of tingling, numbness, pressure, cold, and warmth that are experienced in the absence of a stimulus. concept code: Paronychia display: Paronychia definition: A disorder characterized by an infectious process involving the soft tissues around the nail. concept code: Paroxysmal atrial tachycardia display: Paroxysmal atrial tachycardia definition: A disorder characterized by a dysrhythmia with abrupt onset and sudden termination of atrial contractions with a rate of 150-250 beats per minute. The rhythm disturbance originates in the atria. concept code: Pelvic floor muscle weakness display: Pelvic floor muscle weakness definition: A disorder characterized by a reduction in the strength of the muscles of the pelvic floor. concept code: Pelvic infection display: Pelvic infection definition: A disorder characterized by an infectious process involving the pelvic cavity. concept code: Pelvic pain display: Pelvic pain definition: A disorder characterized by marked discomfort sensation in the pelvis. concept code: Pelvic soft tissue necrosis display: Pelvic soft tissue necrosis definition: A disorder characterized by a necrotic process occurring in the soft tissues of the pelvis. concept code: Penile infection display: Penile infection definition: A disorder characterized by an infectious process involving the penis. concept code: Penile pain display: Penile pain definition: A disorder characterized by marked discomfort sensation in the penis. concept code: Perforation bile duct display: Perforation bile duct definition: A disorder characterized by a rupture in the wall of the extrahepatic or intrahepatic bile duct. concept code: Pericardial effusion display: Pericardial effusion definition: A disorder characterized by fluid collection within the pericardial sac, usually due to inflammation. concept code: Pericardial tamponade display: Pericardial tamponade definition: A disorder characterized by an increase in intrapericardial pressure due to the collection of blood or fluid in the pericardium. concept code: Pericarditis display: Pericarditis definition: A disorder characterized by irritation to the layers of the pericardium (the protective sac around the heart). concept code: Perineal pain display: Perineal pain definition: A disorder characterized by a sensation of marked discomfort in the area between the genital organs and the anus. concept code: Periodontal disease display: Periodontal disease definition: A disorder in the gingival tissue around the teeth. concept code: Periorbital edema display: Periorbital edema definition: A disorder characterized by swelling due to an excessive accumulation of fluid around the orbits of the face. concept code: Periorbital infection display: Periorbital infection definition: A disorder characterized by an infectious process involving the orbit of the eye. concept code: Peripheral ischemia display: Peripheral ischemia definition: A disorder characterized by impaired circulation to an extremity. concept code: Peripheral motor neuropathy display: Peripheral motor neuropathy definition: A disorder characterized by inflammation or degeneration of the peripheral motor nerves. concept code: Peripheral nerve infection display: Peripheral nerve infection definition: A disorder characterized by an infectious process involving the peripheral nerves. concept code: Peripheral sensory neuropathy display: Peripheral sensory neuropathy definition: A disorder characterized by inflammation or degeneration of the peripheral sensory nerves. concept code: Peritoneal infection display: Peritoneal infection definition: A disorder characterized by an infectious process involving the peritoneum. concept code: Peritoneal necrosis display: Peritoneal necrosis definition: A disorder characterized by a necrotic process occurring in the peritoneum. concept code: Personality change display: Personality change definition: A disorder characterized by a conspicuous change in a person's behavior and thinking. concept code: Phantom pain display: Phantom pain definition: A disorder characterized by marked discomfort related to a limb or an organ that is removed from or is not physically part of the body. concept code: Pharyngeal anastomotic leak display: Pharyngeal anastomotic leak definition: A finding of leakage due to breakdown of a pharyngeal anastomosis (surgical connection of two separate anatomic structures). concept code: Pharyngeal fistula display: Pharyngeal fistula definition: A disorder characterized by an abnormal communication between the pharynx and another organ or anatomic site. concept code: Pharyngeal hemorrhage display: Pharyngeal hemorrhage definition: A disorder characterized by bleeding from the pharynx. concept code: Pharyngeal mucositis display: Pharyngeal mucositis definition: A disorder characterized by an inflammation involving the mucous membrane of the pharynx. concept code: Pharyngeal necrosis display: Pharyngeal necrosis definition: A disorder characterized by a necrotic process occurring in the pharynx. concept code: Pharyngeal stenosis display: Pharyngeal stenosis definition: A disorder characterized by a narrowing of the pharyngeal airway. concept code: Pharyngitis display: Pharyngitis definition: A disorder characterized by inflammation of the throat. concept code: Pharyngolaryngeal pain display: Pharyngolaryngeal pain definition: A disorder characterized by marked discomfort sensation in the pharyngolaryngeal region. concept code: Phlebitis display: Phlebitis definition: A disorder characterized by inflammation of the wall of a vein. concept code: Phlebitis infective display: Phlebitis infective definition: A disorder characterized by an infectious process involving the vein. Clinical manifestations include erythema, marked discomfort, swelling, and induration along the course of the infected vein. concept code: Photophobia display: Photophobia definition: A disorder characterized by fear and avoidance of light. concept code: Photosensitivity display: Photosensitivity definition: A disorder characterized by an increase in sensitivity of the skin to light. concept code: Platelet count decreased display: Platelet count decreased definition: A finding based on laboratory test results that indicate a decrease in number of platelets in a blood specimen. concept code: Pleural effusion display: Pleural effusion definition: A disorder characterized by an increase in amounts of fluid within the pleural cavity. Symptoms include shortness of breath, cough and marked chest discomfort. concept code: Pleural hemorrhage display: Pleural hemorrhage definition: A disorder characterized by bleeding from the pleural cavity. concept code: Pleural infection display: Pleural infection definition: A disorder characterized by an infectious process involving the pleura. concept code: Pleuritic pain display: Pleuritic pain definition: A disorder characterized by marked discomfort sensation in the pleura. concept code: Pneumonitis display: Pneumonitis definition: A disorder characterized by inflammation focally or diffusely affecting the lung parenchyma. concept code: Pneumothorax display: Pneumothorax definition: A disorder characterized by abnormal presence of air in the pleural cavity resulting in the collapse of the lung. concept code: Portal hypertension display: Portal hypertension definition: A disorder characterized by an increase in blood pressure in the portal venous system. concept code: Portal vein thrombosis display: Portal vein thrombosis definition: A disorder characterized by the formation of a thrombus (blood clot) in the portal vein. concept code: Postnasal drip display: Postnasal drip definition: A disorder characterized by excessive mucous secretion in the back of the nasal cavity or throat, causing sore throat and/or coughing. concept code: Postoperative hemorrhage display: Postoperative hemorrhage definition: A finding of bleeding occurring after a surgical procedure. concept code: Postoperative thoracic procedure complication display: Postoperative thoracic procedure complication definition: A finding of a previously undocumented problem that occurs after a thoracic procedure. concept code: Precocious puberty display: Precocious puberty definition: A disorder characterized by unusually early development of secondary sexual features; the onset of sexual maturation begins usually before age 8 for girls and before age 9 for boys. concept code: Pregnancy, puerperium and perinatal conditions - Other, Specify display: Pregnancy, puerperium and perinatal conditions - Other, specify definition: No Value Exists concept code: Premature delivery display: Premature delivery definition: A disorder characterized by delivery of a viable infant before the normal end of gestation. Typically, viability is achievable between the twentieth and thirty-seventh week of gestation. concept code: Premature menopause display: Premature menopause definition: A disorder characterized by ovarian failure before the age of 40. Symptoms include hot flashes, night sweats, mood swings and a decrease in sex drive. concept code: Presyncope display: Presyncope definition: A disorder characterized by an episode of lightheadedness and dizziness which may precede an episode of syncope. concept code: Proctitis display: Proctitis definition: A disorder characterized by inflammation of the rectum. concept code: Productive cough display: Productive cough definition: A disorder characterized by expectorated secretions upon coughing. concept code: Prolapse of intestinal stoma display: Prolapse of intestinal stoma definition: A finding of protrusion of the intestinal stoma (surgically created opening on the surface of the body) above the abdominal surface. concept code: Prolapse of urostomy display: Prolapse of urostomy definition: A finding of displacement of the urostomy. concept code: Prostate infection display: Prostate infection definition: A disorder characterized by an infectious process involving the prostate gland. concept code: Prostatic hemorrhage display: Prostatic hemorrhage definition: A disorder characterized by bleeding from the prostate gland. concept code: Prostatic obstruction display: Prostatic obstruction definition: A disorder characterized by compression of the urethra secondary to enlargement of the prostate gland. This results in voiding difficulties (straining to void, slow urine stream, and incomplete emptying of the bladder). concept code: Prostatic pain display: Prostatic pain definition: A disorder characterized by a sensation of marked discomfort in the prostate gland. concept code: Proteinuria display: Proteinuria definition: A disorder characterized by laboratory test results that indicate the presence of excessive protein in the urine. It is predominantly albumin, but also globulin. concept code: Pruritus display: Pruritus definition: A disorder characterized by an intense itching sensation. concept code: Psychiatric disorders - Other, Specify display: Psychiatric disorders - Other, specify definition: No Value Exists concept code: Psychosis display: Psychosis definition: A disorder characterized by personality change, impaired functioning, and loss of touch with reality. It may be a manifestation of schizophrenia, bipolar disorder or brain tumor. concept code: Pulmonary edema display: Pulmonary edema definition: A disorder characterized by accumulation of fluid in the lung tissues that causes a disturbance of the gas exchange that may lead to respiratory failure. concept code: Pulmonary fibrosis display: Pulmonary fibrosis definition: A disorder characterized by the replacement of the lung tissue by connective tissue, leading to progressive dyspnea, respiratory failure or right heart failure. concept code: Pulmonary fistula display: Pulmonary fistula definition: A disorder characterized by an abnormal communication between the lung and another organ or anatomic site. concept code: Pulmonary hypertension display: Pulmonary hypertension definition: A disorder characterized by an increase in pressure within the pulmonary circulation due to lung or heart disorder. concept code: Pulmonary valve disease display: Pulmonary valve disease definition: A disorder characterized by a defect in pulmonary valve function or structure. concept code: Purpura display: Purpura definition: A disorder characterized by hemorrhagic areas of the skin and mucous membrane. Newer lesions appear reddish in color. Older lesions are usually a darker purple color and eventually become a brownish-yellow color. concept code: Pyramidal tract syndrome display: Pyramidal tract syndrome definition: A disorder characterized by dysfunction of the corticospinal (pyramidal) tracts of the spinal cord. Symptoms include an increase in the muscle tone in the lower extremities, hyperreflexia, positive Babinski and a decrease in fine motor coordination. concept code: Radiation recall reaction (dermatologic) display: Radiation recall reaction (dermatologic) definition: A finding of acute skin inflammatory reaction caused by drugs, especially chemotherapeutic agents, for weeks or months following radiotherapy. The inflammatory reaction is confined to the previously irradiated skin and the symptoms disappear after the removal of the pharmaceutical agent. concept code: Radiculitis display: Radiculitis definition: A disorder characterized by inflammation involving a nerve root. Patients experience marked discomfort radiating along a nerve path because of spinal pressure on the connecting nerve root. concept code: Rash acneiform display: Rash acneiform definition: A disorder characterized by an eruption of papules and pustules, typically appearing in face, scalp, upper chest and back. concept code: Rash maculo-papular display: Rash maculo-papular definition: A disorder characterized by the presence of macules (flat) and papules (elevated). Also known as morbillform rash, it is one of the most common cutaneous adverse events, frequently affecting the upper trunk, spreading centripetally and associated with pruritus. concept code: Rash pustular display: Rash pustular definition: A disorder characterized by a circumscribed and elevated skin lesion filled with pus. concept code: Rectal anastomotic leak display: Rectal anastomotic leak definition: A finding of leakage due to breakdown of a rectal anastomosis (surgical connection of two separate anatomic structures). concept code: Rectal fistula display: Rectal fistula definition: A disorder characterized by an abnormal communication between the rectum and another organ or anatomic site. concept code: Rectal hemorrhage display: Rectal hemorrhage definition: A disorder characterized by bleeding from the rectal wall and discharged from the anus. concept code: Rectal mucositis display: Rectal mucositis definition: A disorder characterized by inflammation of the mucous membrane of the rectum. concept code: Rectal necrosis display: Rectal necrosis definition: A disorder characterized by a necrotic process occurring in the rectal wall. concept code: Rectal obstruction display: Rectal obstruction definition: A disorder characterized by blockage of the normal flow of the intestinal contents in the rectum. concept code: Rectal pain display: Rectal pain definition: A disorder characterized by a sensation of marked discomfort in the rectal region. concept code: Rectal perforation display: Rectal perforation definition: A disorder characterized by a rupture in the rectal wall. concept code: Rectal stenosis display: Rectal stenosis definition: A disorder characterized by a narrowing of the lumen of the rectum. concept code: Rectal ulcer display: Rectal ulcer definition: A disorder characterized by a circumscribed, inflammatory and necrotic erosive lesion on the mucosal surface of the rectum. concept code: Recurrent laryngeal nerve palsy display: Recurrent laryngeal nerve palsy definition: A disorder characterized by paralysis of the recurrent laryngeal nerve. concept code: Renal and urinary disorders - Other, Specify display: Renal and urinary disorders - Other, specify definition: No Value Exists concept code: Renal calculi display: Renal calculi definition: A disorder characterized by the formation of crystals in the pelvis of the kidney. concept code: Renal colic display: Renal colic definition: A disorder characterized by paroxysmal and severe flank marked discomfort radiating to the inguinal area. Often, the cause is the passage of kidney stones. concept code: Renal hemorrhage display: Renal hemorrhage definition: A disorder characterized by bleeding from the kidney. concept code: Reproductive system and breast disorders - Other, Specify display: Reproductive system and breast disorders - Other, specify definition: No Value Exists concept code: Respiratory failure display: Respiratory failure definition: A disorder characterized by impaired gas exchange by the respiratory system resulting in hypoxemia and a decrease in oxygenation of the tissues that may be associated with an increase in arterial levels of carbon dioxide. concept code: Respiratory, thoracic and mediastinal disorders - Other, Specify display: Respiratory, thoracic and mediastinal disorders - Other, specify definition: No Value Exists concept code: Restlessness display: Restlessness definition: A disorder characterized by an inability to rest, relax or be still. concept code: Restrictive cardiomyopathy display: Restrictive cardiomyopathy definition: A disorder characterized by an inability of the ventricles to fill with blood because the myocardium (heart muscle) stiffens and loses its flexibility. concept code: Retinal detachment display: Retinal detachment definition: A disorder characterized by the separation of the inner retina layers from the underlying pigment epithelium. concept code: Retinal tear display: Retinal tear definition: A disorder characterized by a small laceration of the retina, this occurs when the vitreous separates from the retina. Symptoms include flashes and floaters. concept code: Retinal vascular disorder display: Retinal vascular disorder definition: A disorder characterized by pathological retinal blood vessels that adversely affects vision. concept code: Retinoic acid syndrome display: Retinoic acid syndrome definition: A disorder characterized by weight gain, dyspnea, pleural and pericardial effusions, leukocytosis and/or renal failure originally described in patients treated with all-trans retinoic acid. concept code: Retinopathy display: Retinopathy definition: A disorder involving the retina. concept code: Retroperitoneal hemorrhage display: Retroperitoneal hemorrhage definition: A disorder characterized by bleeding from the retroperitoneal area. concept code: Reversible posterior leukoencephalopathy syndrome display: Reversible posterior leukoencephalopathy syndrome definition: A disorder characterized by headaches, mental status changes, visual disturbances, and seizures associated with imaging findings of posterior leukoencephalopathy. It has been observed in association with hypertensive encephalopathy, eclampsia, and immunosuppressive and cytotoxic drug treatment. It is an acute or subacute reversible condition. concept code: Rhinitis infective display: Rhinitis infective definition: A disorder characterized by an infectious process involving the nasal mucosal. concept code: Right ventricular dysfunction display: Right ventricular dysfunction definition: A disorder characterized by impairment of right ventricular function associated with low ejection fraction and a decrease in motility of the right ventricular wall. concept code: Salivary duct inflammation display: Salivary duct inflammation definition: A disorder characterized by inflammation of the salivary duct. concept code: Salivary gland fistula display: Salivary gland fistula definition: A disorder characterized by an abnormal communication between a salivary gland and another organ or anatomic site. concept code: Salivary gland infection display: Salivary gland infection definition: A disorder characterized by an infectious process involving the salivary gland. concept code: Scalp pain display: Scalp pain definition: A disorder characterized by marked discomfort sensation in the skin covering the top and the back of the head. concept code: Scleral disorder display: Scleral disorder definition: A disorder characterized by involvement of the sclera of the eye. concept code: Scoliosis display: Scoliosis definition: A disorder characterized by a malformed, lateral curvature of the spine. concept code: Scrotal infection display: Scrotal infection definition: A disorder characterized by an infectious process involving the scrotum. concept code: Scrotal pain display: Scrotal pain definition: A disorder characterized by marked discomfort sensation in the scrotal area. concept code: Seizure display: Seizure definition: A disorder characterized by a sudden, involuntary skeletal muscular contractions of cerebral or brain stem origin. concept code: Sepsis display: Sepsis definition: A disorder characterized by the presence of pathogenic microorganisms in the blood stream that cause a rapidly progressing systemic reaction that may lead to shock. concept code: Seroma display: Seroma definition: A finding of tumor-like collection of serum in the tissues. concept code: Serum amylase increased display: Serum amylase increased definition: A finding based on laboratory test results that indicate an increase in the levels of amylase in a serum specimen. concept code: Serum sickness display: Serum sickness definition: A disorder characterized by a delayed-type hypersensitivity reaction to foreign proteins derived from an animal serum. It occurs approximately six to twenty-one days following the administration of the foreign antigen. Symptoms include fever, arthralgias, myalgias, skin eruptions, lymphadenopathy, chest marked discomfort and dyspnea. concept code: Sick sinus syndrome display: Sick sinus syndrome definition: A disorder characterized by a dysrhythmia with alternating periods of bradycardia and atrial tachycardia accompanied by syncope, fatigue and dizziness. concept code: Sinus bradycardia display: Sinus bradycardia definition: A disorder characterized by a dysrhythmia with a heart rate less than 60 beats per minute that originates in the sinus node. concept code: Sinus disorder display: Sinus disorder definition: A disorder characterized by involvement of the paranasal sinuses. concept code: Sinus pain display: Sinus pain definition: A disorder characterized by marked discomfort in the face, between the eyes, or upper teeth originating from the sinuses. concept code: Sinus tachycardia display: Sinus tachycardia definition: A disorder characterized by a dysrhythmia with a heart rate greater than 100 beats per minute that originates in the sinus node. concept code: Sinusitis display: Sinusitis definition: A disorder characterized by an infectious process involving the mucous membranes of the paranasal sinuses. concept code: Skin and subcutaneous tissue disorders - Other, Specify display: Skin and subcutaneous tissue disorders - Other, specify definition: No Value Exists concept code: Skin atrophy display: Skin atrophy definition: A disorder characterized by the degeneration and thinning of the epidermis and dermis. concept code: Skin hyperpigmentation display: Skin hyperpigmentation definition: A disorder characterized by darkening of the skin due to excessive melanin deposition. concept code: Skin hypopigmentation display: Skin hypopigmentation definition: A disorder characterized by loss of skin pigment. concept code: Skin induration display: Skin induration definition: A disorder characterized by an area of hardness in the skin. concept code: Skin infection display: Skin infection definition: A disorder characterized by an infectious process involving the skin. concept code: Skin ulceration display: Skin ulceration definition: A disorder characterized by circumscribed, inflammatory and necrotic erosive lesion on the skin. concept code: Sleep apnea display: Sleep apnea definition: A disorder characterized by cessation of breathing for short periods during sleep. concept code: Small intestinal anastomotic leak display: Small intestinal anastomotic leak definition: A finding of leakage due to breakdown of an anastomosis (surgical connection of two separate anatomic structures) in the small bowel. concept code: Small intestinal mucositis display: Small intestinal mucositis definition: A disorder characterized by inflammation of the mucous membrane of the small intestine. concept code: Small intestinal obstruction display: Small intestinal obstruction definition: A disorder characterized by blockage of the normal flow of the intestinal contents. concept code: Small intestinal perforation display: Small intestinal perforation definition: A disorder characterized by a rupture in the small intestine wall. concept code: Small intestinal stenosis display: Small intestinal stenosis definition: A disorder characterized by a narrowing of the lumen of the small intestine. concept code: Small intestine infection display: Small intestine infection definition: A disorder characterized by an infectious process involving the small intestine. concept code: Small intestine ulcer display: Small intestine ulcer definition: A disorder characterized by a circumscribed, inflammatory and necrotic erosive lesion on the mucosal surface of the small intestine. concept code: Sneezing display: Sneezing definition: A disorder characterized by the involuntary expulsion of air from the nose. concept code: Social circumstances - Other, Specify display: Social circumstances - Other, specify definition: No Value Exists concept code: Soft tissue infection display: Soft tissue infection definition: A disorder characterized by an infectious process involving soft tissues. concept code: Soft tissue necrosis lower limb display: Soft tissue necrosis lower limb definition: A disorder characterized by a necrotic process occurring in the soft tissues of the lower extremity. concept code: Soft tissue necrosis upper limb display: Soft tissue necrosis upper limb definition: A disorder characterized by a necrotic process occurring in the soft tissues of the upper extremity. concept code: Somnolence display: Somnolence definition: A disorder characterized by characterized by excessive sleepiness and drowsiness. concept code: Sore throat display: Sore throat definition: A disorder characterized by of marked discomfort in the throat concept code: Spasticity display: Spasticity definition: A disorder characterized by increased involuntary muscle tone that affects the regions interfering with voluntary movement. It results in gait, movement, and speech disturbances. concept code: Spermatic cord anastomotic leak display: Spermatic cord anastomotic leak definition: A finding of leakage due to breakdown of a spermatic cord anastomosis (surgical connection of two separate anatomic structures). concept code: Spermatic cord hemorrhage display: Spermatic cord hemorrhage definition: A disorder characterized by bleeding from the spermatic cord. concept code: Spermatic cord obstruction display: Spermatic cord obstruction definition: A disorder characterized by blockage of the normal flow of the contents of the spermatic cord. concept code: Spinal fracture display: Spinal fracture definition: A finding of traumatic injury to the spine in which the continuity of a vertebral bone is broken. concept code: Spleen disorder display: Spleen disorder definition: A disorder of the spleen. concept code: Splenic infection display: Splenic infection definition: A disorder characterized by an infectious process involving the spleen. concept code: Stenosis of gastrointestinal stoma display: Stenosis of gastrointestinal stoma definition: A finding of narrowing of the gastrointestinal stoma (surgically created opening on the surface of the body). concept code: Stevens-Johnson syndrome display: Stevens-Johnson syndrome definition: A disorder characterized by less than 10% total body skin area separation of dermis. The syndrome is thought to be a hypersensitivity complex affecting the skin and the mucous membranes. concept code: Stoma site infection display: Stoma site infection definition: A disorder characterized by an infectious process involving a stoma (surgically created opening on the surface of the body). concept code: Stomach pain display: Stomach pain definition: A disorder characterized by a sensation of marked discomfort in the stomach. concept code: Stomal ulcer display: Stomal ulcer definition: A disorder characterized by a circumscribed, inflammatory and necrotic erosive lesion on the jejunal mucosal surface close to the anastomosis site following a gastroenterostomy procedure. concept code: Stridor display: Stridor definition: A disorder characterized by a high pitched breathing sound due to laryngeal or upper airway obstruction. concept code: Stroke display: Stroke definition: A disorder characterized by a sudden loss of sensory function due to an intracranial vascular event. concept code: Sudden death NOS display: Sudden death NOS definition: An unexpected cessation of life that cannot be attributed to a CTCAE term associated with Grade 5. concept code: Suicidal ideation display: Suicidal ideation definition: A disorder characterized by thoughts of taking one's own life. concept code: Suicide attempt display: Suicide attempt definition: A disorder characterized by self-inflicted harm in an attempt to end one's own life. concept code: Superficial soft tissue fibrosis display: Superficial soft tissue fibrosis definition: A disorder characterized by fibrotic degeneration of the superficial soft tissues. concept code: Superficial thrombophlebitis display: Superficial thrombophlebitis definition: A disorder characterized by a blood clot and inflammation involving a superficial vein of the extremities. concept code: Superior vena cava syndrome display: Superior vena cava syndrome definition: A disorder characterized by obstruction of the blood flow in the superior vena cava. Signs and symptoms include swelling and cyanosis of the face, neck, and upper arms, cough, orthopnea and headache. concept code: Supraventricular tachycardia display: Supraventricular tachycardia definition: A disorder characterized by a dysrhythmia with a heart rate greater than 100 beats per minute that originates above the ventricles. concept code: Surgical and medical procedures - Other, Specify display: Surgical and medical procedures - Other, specify definition: No Value Exists concept code: Syncope display: Syncope definition: A disorder characterized by spontaneous loss of consciousness caused by insufficient blood supply to the brain. concept code: Telangiectasia display: Telangiectasia definition: A disorder characterized by local dilatation of small vessels resulting in red discoloration of the skin or mucous membranes. concept code: Testicular disorder display: Testicular disorder definition: A disorder characterized by involvement of the testis. concept code: Testicular hemorrhage display: Testicular hemorrhage definition: A disorder characterized by bleeding from the testis. concept code: Testicular pain display: Testicular pain definition: A disorder characterized by a sensation of marked discomfort in the testis. concept code: Thromboembolic event display: Thromboembolic event definition: A disorder characterized by occlusion of a vessel by a thrombus that has migrated from a distal site via the blood stream. concept code: Thrombotic thrombocytopenic purpura display: Thrombotic thrombocytopenic purpura definition: A disorder characterized by the presence of microangiopathic hemolytic anemia, thrombocytopenic purpura, fever, renal abnormalities and neurological abnormalities such as seizures, hemiplegia, and visual disturbances. It is an acute or subacute condition. concept code: Tinnitus display: Tinnitus definition: A disorder characterized by noise in the ears, such as ringing, buzzing, roaring or clicking. concept code: Tooth development disorder display: Tooth development disorder definition: A disorder characterized by a pathological process of the teeth occurring during tooth development. concept code: Tooth discoloration display: Tooth discoloration definition: A disorder characterized by a change in tooth hue or tint. concept code: Tooth infection display: Tooth infection definition: A disorder characterized by an infectious process involving a tooth. concept code: Toothache display: Toothache definition: A disorder characterized by a sensation of marked discomfort in the tooth. concept code: Toxic epidermal necrolysis display: Toxic epidermal necrolysis definition: A disorder characterized by greater than 30% total body skin area separation of dermis. The syndrome is thought to be a hypersensitivity complex affecting the skin and the mucous membranes. concept code: Tracheal fistula display: Tracheal fistula definition: A disorder characterized by an abnormal communication between the trachea and another organ or anatomic site. concept code: Tracheal hemorrhage display: Tracheal hemorrhage definition: A finding of bleeding from the trachea. concept code: Tracheal mucositis display: Tracheal mucositis definition: A disorder characterized by an inflammation involving the mucous membrane of the trachea. concept code: Tracheal obstruction display: Tracheal obstruction definition: A finding of blockage of the lumen of the trachea. concept code: Tracheal stenosis display: Tracheal stenosis definition: A disorder characterized by a narrowing of the trachea. concept code: Tracheitis display: Tracheitis definition: A disorder characterized by an infectious process involving the trachea. concept code: Tracheostomy site bleeding display: Tracheostomy site bleeding definition: A finding of blood leakage from the tracheostomy site. concept code: Transient ischemic attacks display: Transient ischemic attacks definition: A disorder characterized by a brief attack (less than 24 hours) of cerebral dysfunction of vascular origin, with no persistent neurological deficit. concept code: Treatment related secondary malignancy display: Treatment related secondary malignancy definition: A disorder characterized by development of a malignancy most probably as a result of treatment for a previously existing malignancy. concept code: Tremor display: Tremor definition: A disorder characterized by the uncontrolled shaking movement of the whole body or individual parts. concept code: Tricuspid valve disease display: Tricuspid valve disease definition: A disorder characterized by a defect in tricuspid valve function or structure. concept code: Trigeminal nerve disorder display: Trigeminal nerve disorder definition: A disorder characterized by involvement of the trigeminal nerve (fifth cranial nerve). concept code: Trismus display: Trismus definition: A disorder characterized by lack of ability to open the mouth fully due to a decrease in the range of motion of the muscles of mastication. concept code: Tumor lysis syndrome display: Tumor lysis syndrome definition: A disorder characterized by metabolic abnormalities that result from a spontaneous or therapy-related cytolysis of tumor cells. concept code: Tumor pain display: Tumor pain definition: A disorder characterized by marked discomfort from a neoplasm that may be pressing on a nerve, blocking blood vessels, inflamed or fractured from metastasis. concept code: Typhlitis display: Typhlitis definition: A disorder characterized by inflammation of the cecum. concept code: Unequal limb length display: Unequal limb length definition: A disorder characterized by of a discrepancy between the lengths of the lower or upper extremities. concept code: Unintended pregnancy display: Unintended pregnancy definition: A disorder characterized by an unexpected pregnancy at the time of conception. concept code: Upper gastrointestinal hemorrhage display: Upper gastrointestinal hemorrhage definition: A disorder characterized by bleeding from the upper gastrointestinal tract (oral cavity, pharynx, esophagus, and stomach). concept code: Upper respiratory infection display: Upper respiratory infection definition: A disorder characterized by an infectious process involving the upper respiratory tract (nose, paranasal sinuses, pharynx, larynx, or trachea). concept code: Ureteric anastomotic leak display: Ureteric anastomotic leak definition: A finding of leakage due to breakdown of a ureteral anastomosis (surgical connection of two separate anatomic structures). concept code: Urethral anastomotic leak display: Urethral anastomotic leak definition: A finding of leakage due to breakdown of a urethral anastomosis (surgical connection of two separate anatomic structures). concept code: Urethral infection display: Urethral infection definition: A disorder characterized by an infectious process involving the urethra. concept code: Urinary fistula display: Urinary fistula definition: A disorder characterized by an abnormal communication between any part of the urinary system and another organ or anatomic site. concept code: Urinary frequency display: Urinary frequency definition: A disorder characterized by urination at short intervals. concept code: Urinary incontinence display: Urinary incontinence definition: A disorder characterized by inability to control the flow of urine from the bladder. concept code: Urinary retention display: Urinary retention definition: A disorder characterized by accumulation of urine within the bladder because of the inability to urinate. concept code: Urinary tract infection display: Urinary tract infection definition: A disorder characterized by an infectious process involving the urinary tract, most commonly the bladder and the urethra. concept code: Urinary tract obstruction display: Urinary tract obstruction definition: A disorder characterized by blockage of the normal flow of contents of the urinary tract. concept code: Urinary tract pain display: Urinary tract pain definition: A disorder characterized by a sensation of marked discomfort in the urinary tract. concept code: Urinary urgency display: Urinary urgency definition: A disorder characterized by a sudden compelling urge to urinate. concept code: Urine discoloration display: Urine discoloration definition: A disorder characterized by a change in the color of the urine. concept code: Urine output decreased display: Urine output decreased definition: A finding based on test results that indicate urine production is less relative to previous output. concept code: Urostomy leak display: Urostomy leak definition: A finding of leakage of contents from a urostomy. concept code: Urostomy obstruction display: Urostomy obstruction definition: A finding of blockage of the urostomy. concept code: Urostomy site bleeding display: Urostomy site bleeding definition: A finding of bleeding from the urostomy site. concept code: Urostomy stenosis display: Urostomy stenosis definition: A finding of narrowing of the opening of a urostomy. concept code: Urticaria display: Urticaria definition: A disorder characterized by an itchy skin eruption characterized by wheals with pale interiors and well-defined red margins. concept code: Uterine anastomotic leak display: Uterine anastomotic leak definition: A finding of leakage due to breakdown of a uterine anastomosis (surgical connection of two separate anatomic structures). concept code: Uterine fistula display: Uterine fistula definition: A disorder characterized by an abnormal communication between the uterus and another organ or anatomic site. concept code: Uterine hemorrhage display: Uterine hemorrhage definition: A disorder characterized by bleeding from the uterus. concept code: Uterine infection display: Uterine infection definition: A disorder characterized by an infectious process involving the endometrium. It may extend to the myometrium and parametrial tissues. concept code: Uterine obstruction display: Uterine obstruction definition: A disorder characterized by blockage of the uterine outlet. concept code: Uterine pain display: Uterine pain definition: A disorder characterized by a sensation of marked discomfort in the uterus. concept code: Uterine perforation display: Uterine perforation definition: A disorder characterized by a rupture in the uterine wall. concept code: Uveitis display: Uveitis definition: A disorder characterized by inflammation to the uvea of the eye. concept code: Vaginal anastomotic leak display: Vaginal anastomotic leak definition: A finding of leakage due to breakdown of a vaginal anastomosis (surgical connection of two separate anatomic structures). concept code: Vaginal discharge display: Vaginal discharge definition: A disorder characterized by vaginal secretions. Mucus produced by the cervical glands is discharged from the vagina naturally, especially during the childbearing years. concept code: Vaginal dryness display: Vaginal dryness definition: A disorder characterized by an uncomfortable feeling of itching and burning in the vagina. concept code: Vaginal fistula display: Vaginal fistula definition: A disorder characterized by an abnormal communication between the vagina and another organ or anatomic site. concept code: Vaginal hemorrhage display: Vaginal hemorrhage definition: A disorder characterized by bleeding from the vagina. concept code: Vaginal infection display: Vaginal infection definition: A disorder characterized by an infectious process involving the vagina. concept code: Vaginal inflammation display: Vaginal inflammation definition: A disorder characterized by inflammation involving the vagina. Symptoms may include redness, edema, marked discomfort and an increase in vaginal discharge. concept code: Vaginal obstruction display: Vaginal obstruction definition: A disorder characterized by blockage of vaginal canal. concept code: Vaginal pain display: Vaginal pain definition: A disorder characterized by a sensation of marked discomfort in the vagina. concept code: Vaginal perforation display: Vaginal perforation definition: A disorder characterized by a rupture in the vaginal wall. concept code: Vaginal stricture display: Vaginal stricture definition: A disorder characterized by a narrowing of the vaginal canal. concept code: Vaginismus display: Vaginismus definition: A disorder characterized by involuntary spasms of the pelvic floor muscles, resulting in pathologic tightness of the vaginal wall during penetration such as during sexual intercourse. concept code: Vagus nerve disorder display: Vagus nerve disorder definition: A disorder characterized by involvement of the vagus nerve (tenth cranial nerve). concept code: Vas deferens anastomotic leak display: Vas deferens anastomotic leak definition: A finding of leakage due to breakdown of a vas deferens anastomosis (surgical connection of two separate anatomic structures). concept code: Vascular access complication display: Vascular access complication definition: A finding of a previously undocumented problem related to the vascular access site. concept code: Vascular disorders - Other, Specify display: Vascular disorders - Other, specify definition: No Value Exists concept code: Vasculitis display: Vasculitis definition: A disorder characterized by inflammation involving the wall of a vessel. concept code: Vasovagal reaction display: Vasovagal reaction definition: A disorder characterized by a sudden drop of the blood pressure, bradycardia, and peripheral vasodilation that may lead to loss of consciousness. It results from an increase in the stimulation of the vagus nerve. concept code: Venous injury display: Venous injury definition: A finding of damage to a vein. concept code: Ventricular arrhythmia display: Ventricular arrhythmia definition: A disorder characterized by a dysrhythmia that originates in the ventricles. concept code: Ventricular fibrillation display: Ventricular fibrillation definition: A disorder characterized by a dysrhythmia without discernible QRS complexes due to rapid repetitive excitation of myocardial fibers without coordinated contraction of the ventricles. concept code: Ventricular tachycardia display: Ventricular tachycardia definition: A disorder characterized by a dysrhythmia with a heart rate greater than 100 beats per minute that originates distal to the bundle of His. concept code: Vertigo display: Vertigo definition: A disorder characterized by a sensation as if the external world were revolving around the patient (objective vertigo) or as if he himself were revolving in space (subjective vertigo). concept code: Vestibular disorder display: Vestibular disorder definition: A disorder characterized by dizziness, imbalance, nausea, and vision problems. concept code: Virilization display: Virilization definition: A disorder characterized by inappropriate masculinization occurring in a female or prepubertal male. concept code: Visceral arterial ischemia display: Visceral arterial ischemia definition: A disorder characterized by a decrease in blood supply due to narrowing or blockage of a visceral (mesenteric) artery. concept code: Vital capacity abnormal display: Vital capacity abnormal definition: A finding based on pulmonary function test results that indicate an abnormal vital capacity (amount of exhaled after a maximum inhalation) when compared to the predicted value. concept code: Vitreous hemorrhage display: Vitreous hemorrhage definition: A disorder characterized by blood extravasation into the vitreous humor. concept code: Voice alteration display: Voice alteration definition: A disorder characterized by a change in the sound and/or speed of the voice. concept code: Vomiting display: Vomiting definition: A disorder characterized by the reflexive act of ejecting the contents of the stomach through the mouth. concept code: Vulval infection display: Vulval infection definition: A disorder characterized by an infectious process involving the vulva. concept code: Watering eyes display: Watering eyes definition: A disorder of excessive tearing in the eyes; it can be caused by overproduction of tears or impaired drainage of the tear duct. concept code: Weight gain display: Weight gain definition: A finding characterized by an increase in overall body weight; for pediatrics, greater than the baseline growth curve. concept code: Weight loss display: Weight loss definition: A finding characterized by a decrease in overall body weight; for pediatrics, less than the baseline growth curve. concept code: Wheezing display: Wheezing definition: A disorder characterized by a high-pitched, whistling sound during breathing. It results from the narrowing or obstruction of the respiratory airways. concept code: White blood cell decreased display: White blood cell decreased definition: A finding based on laboratory test results that indicate an decrease in number of white blood cells in a blood specimen. concept code: Wolff-Parkinson-White syndrome display: Wolff-Parkinson-White syndrome definition: A disorder characterized by the presence of an accessory conductive pathway between the atria and the ventricles that causes premature ventricular activation. concept code: Wound complication display: Wound complication definition: A finding of development of a new problem at the site of an existing wound. concept code: Wound dehiscence display: Wound dehiscence definition: A finding of separation of the approximated margins of a surgical wound. concept code: Wound infection display: Wound infection definition: A disorder characterized by an infectious process involving the wound. concept code: Wrist fracture display: Wrist fracture definition: A finding of traumatic injury to the wrist joint in which the continuity of a wrist bone is broken. ValueSet #d1e14927-vs status: Active compose Includes - System * http://example.org/nci.nih.gov/xml/owl/cadsr/form/form_design_identifier/3265657v2.0/question_identifier#3556214v2.0-cs CodeSystem #d1e54652-cs url: http://example.org/nci.nih.gov/xml/owl/cadsr/form/form_design_identifier/3265657v2.0/question_identifier#3557008v2.0-cs status: Active caseSensitive: true content: Complete concept code: 1 display: Mild Adverse Event definition: An adverse event that is asymptomatic; or involves mild or minor symptoms; or is of marginal clinical relevance; or consists of clinical or diagnostic observations alone; or for which intervention is not indicated; or for which only non-prescription intervention is indicated. concept code: 2 display: Moderate Adverse Event definition: An adverse event for which only minimal, local, or noninvasive intervention (e.g. packing, cautery) is indicated; or that limits instrumental activities of daily living (ADLs, e.g., shopping, laundry, transportation, or ability to conduct finances). concept code: 3 display: Severe Adverse Event definition: An adverse event that is medically significant but not life-threatening; or for which inpatient care or prolongation of hospitalization are indicated; or that is an important medical event that does not result in hospitalization, but may jeopardize the patient or may require intervention either to prevent hospitalization, to prevent the AE from becoming life-threatening or causing death; or that is disabling; or that results in persistent or significant disability, incapcity, or limitation of self care activities of daily living (ADLs, e.g., getting in and our of bed, dressing, eating, getting around inside, bathing, or using the toilet). concept code: 4 display: Life Threatening Adverse Event definition: An adverse event that has life-threatening consequences; for which urgent intervention is indicated; that puts the patient at risk of death at the time of the event if immediate intervention is not undertaken; or that causes blindness or deafness. concept code: 5 display: Death Related to Adverse Event definition: The termination of life associated with an adverse event. ValueSet #d1e54652-vs status: Active compose Includes - System * http://example.org/nci.nih.gov/xml/owl/cadsr/form/form_design_identifier/3265657v2.0/question_identifier#3557008v2.0-cs CodeSystem #d1e55041-cs url: http://example.org/nci.nih.gov/xml/owl/cadsr/form/form_design_identifier/3265657v2.0/question_identifier#3557021v2.0-cs status: Active caseSensitive: true content: Complete concept code: Yes display: Yes definition: The affirmative response to a question or activity. concept code: No display: No definition: The non-affirmative response to a question. ValueSet #d1e55041-vs status: Active compose Includes - System * http://example.org/nci.nih.gov/xml/owl/cadsr/form/form_design_identifier/3265657v2.0/question_identifier#3557021v2.0-cs CodeSystem #d1e55265-cs url: http://example.org/nci.nih.gov/xml/owl/cadsr/form/form_design_identifier/3265657v2.0/question_identifier#3557032v2.0-cs status: Active caseSensitive: true content: Complete concept code: Biological Therapy display: Biological Therapy definition: Biological therapy is a form of treatment that implies the administration of substances which produce a biological reaction in the organism enhancing or restoring the host immune response, modifying the behavior of cancer cells, blocking the pathways of cell neoplastic transformation and tumor ability to metastasize, or facilitating the repairment of cells damaged by aggressive forms of cancer treatment. It includes the use of sera, antitoxins, vaccines, genes, cells, tissues, and organs concept code: Chemotherapy display: CHEMOTHERAPY definition: CHEMOTHERAPY concept code: Combined modality display: combined modality definition: combined modality concept code: Concomitant medication display: Concomitant Agent definition: A pharmaceutical agent other than agent(s) tested in a given protocol that is administered to or used by a subject either prior to or during the study. Supportive care and essential ancillary medications required by a treatment regimen should be clearly identified. A protocol complete instructions including appropriate indication, dosage, administration route, schedule, restrictions to use, and any other relevant data should be explicitly stated. Concept also refers to substance(s) used prior or during the study that are not specified by the protocol. concept code: Device display: Medical_Device definition: Medical device - any machinery designed to aid diagnostic and medical therapies. Medical device has to be designed with rigorous safety standards. There are several basic types of medical devices: life support equipment used to maintain a patient's body functions; therapeutic equipment; monitors and detectors to measure the indexes of a patient's state; imagine machines and laboratory equipment used with diagnostic and status monitoring purposes. In insurance parlance, the term is usually synonymous with assistive device, although it may include medical supplies. concept code: Disease display: disease definition: disease concept code: Endocrine Therapy display: Endocrine Therapy definition: Various treatment modalities that produce the desired therapeutic effect by means of change of hormone/hormones level. The treatment may include administration of hormones or hormone analogs to the patient, or decreasing the level of hormones in the body by using hormone antagonists, or hormone ablation therapy. The concept covers but not limited to: intermittent or permanent hormone suppression or ablation in treatment of hormone-dependent tumors, hormone replacement therapy of any kind, hormonal component of gender reassignment therapy, hormonal contraception, surgical and radiation castration. concept code: Immunotherapy display: Immunotherapy definition: (IM-yoo-no-THER-a-pee) Treatment to stimulate or restore the ability of the immune system to fight infections and other diseases. Also used to lessen side effects that may be caused by some cancer treatments. concept code: Investigational agent display: Investigational Agent definition: In the process of being studied; experimental. (NCI): An active power or cause (as principle, substance, physical or biological factor, etc.) that produces a specific effect. (NCI) concept code: Other display: Other definition: Not otherwise specified. concept code: Radiation therapy display: Radiation Therapy definition: use PHOTOTHERAPY, LASER THERAPY, or ULTRAVIOLET THERAPY for therapeutic radiation with visible, laser, or ultraviolet light, respectively. concept code: Surgery display: Surgery definition: A specialty in which manual or operative procedures are used in the treatment of disease, injuries, or deformities. ValueSet #d1e55265-vs status: Active compose Includes - System * http://example.org/nci.nih.gov/xml/owl/cadsr/form/form_design_identifier/3265657v2.0/question_identifier#3557032v2.0-cs CodeSystem #d1e56008-cs url: http://example.org/nci.nih.gov/xml/owl/cadsr/form/form_design_identifier/3265657v2.0/question_identifier#3557869v2.0-cs status: Active caseSensitive: true content: Complete concept code: Blood and lymphatic system disorders display: Hematopoietic and Lymphoid System Disorder definition: Any deviation from the normal structure or function of the blood or lymphatic system that is manifested by a characteristic set of symptoms and signs. concept code: Cardiac disorders display: Cardiac disorders definition: Any deviation from the normal structure or function of the cardiac system that is manifested by a characteristic set of symptoms and signs. concept code: Congenital, familial and genetic disorders display: Congenital, Familial and Genetic Disorder Class definition: A class of disorders that encompasses conditions resulting from a congenital, familial hereditary trait or genetic abnormality as is manifested by a characterstic set of symptoms and signs. concept code: Ear and labyrinth disorders display: Ear and Labyrinth Disorder Class definition: Any deviation from the normal structure or function of the ear or labyrinth that is manifested by a characteristic set of symptoms and signs. concept code: Endocrine disorders display: Endocrine Disorder definition: Any deviation from the normal structure or function of the endocrine system that is manifested by a characteristic set of symptoms and signs. concept code: Eye disorders display: Eye Disorder definition: Any deviation from the normal structure or function of the eye that is manifested by a characteristic set of symptoms and signs. concept code: Gastrointestinal disorders display: Gastrointestinal Disorder definition: Diseases of the digestive tract (oral cavity to anus) and associated organs (salivary glands, liver, pancreas). concept code: General disorders and administration site conditions display: General Disorders and Administration Site Conditions Class definition: A class of disorders that encompasses conditions of a general kind that result from a disease, the treatment of disease or administration of treatment at a particular site and are manifested by a characteristic set of symptoms and signs. concept code: Hepatobiliary disorders display: Liver and Biliary Tract Disorder definition: Any deviation from the normal structure or function of the liver or biliary tract that is manifested by a characteristic set of symptoms and signs. concept code: Immune system disorders display: Immune System Disorder definition: A disorder resulting from an abnormality in the immune system. -- 2003 concept code: Infections and infestations display: Infection and infestation definition: A disorder resulting from the presence and activity of a microbial, viral, or parasitic agent. It can be transmitted by direct or indirect contact. -- 2003 concept code: Injury, poisoning and procedural complications display: Injury, Poisoning and Procedural Complication Class definition: A class of disorders that encompasses conditions resulting from an injury, poisoning or procedure. concept code: Investigations display: Investigation definition: The act or process of a systematic and thorough examination; research, study; the process of inquiring into or following up, intended to develop facts. concept code: Metabolism and nutrition disorders display: Metabolism and Nutrition Disorder Class definition: A class of disorders that encompasses conditions occurring as a result of metabolic dysfunction or deviation from the normal nutritional requirements. concept code: Musculoskeletal and connective tissue disorders display: Connective and Soft Tissue Disorder definition: Any deviation from the normal structure or function of the musculoskeletal or connective tissue that is manifested by a characteristic set of symptoms and signs. concept code: Neoplasms benign, malignant and unspecified (incl cysts and polyps) display: Neoplasm definition: An abnormal tissue growth resulted from uncontrolled cell proliferation. Benign neoplastic cells resemble normal cells without exhibiting significant cytologic atypia, while malignant ones exhibit overt signs such as dysplastic features, atypical mitotic figures, necrosis, nuclear pleomorphism, and anaplasia. Representative examples of benign neoplasms include papillomas, cystadenomas, and lipomas; malignant neoplasms include carcinomas, sarcomas, lymphomas, and leukemias. concept code: Nervous system disorders display: Nervous System Disorder definition: Any deviation from the normal structure or function of the nervous system that is manifested by a characteristic set of symptoms and signs. concept code: Pregnancy, puerperium and perinatal conditions display: Pregnancy, Puerperium and Perinatal Condition Class definition: A class of conditions associated with pregnancy, puerperium and perinatal status. concept code: Psychiatric disorders display: Psychiatric Disorder definition: Any deviation from the normal structure or function of the brain and a psychiatric condition, that results in an impairment of an individual's normal cognitive, emotional, or behavioral functioning, and is caused by physiological or psychosocial factors. concept code: Renal and urinary disorders display: Urinary Tract Disorder definition: Disorders of any part of the urologic system. concept code: Reproductive system and breast disorders display: Reproductive System and Breast Disorder Class definition: Any deviation from the normal structure or function of the reproductive system or breast that is manifested by a characteristic set of symptoms and signs. concept code: Respiratory, thoracic and mediastinal disorders display: Respiratory and Thoracic Disorder definition: Any deviation from the normal structure or function of the respiratory system including the thorax and mediastinum that is manifested by a characteristic set of symptoms and signs. concept code: Skin and subcutaneous tissue disorders display: Skin Disorder definition: Any deviation from the normal structure or function of the skin or subcutaneous tissue that is manifested by a characteristic set of symptoms and signs. concept code: Social circumstances display: Social Circumstances definition: A set of concepts that results from or is influenced by criteria or activities associated with the social environment of a person. concept code: Surgical and medical procedures display: Intervention or Procedure definition: An activity that produces an effect, or that is intended to alter the course of a disease in a patient or population. This is a general term that encompasses the medical, social, behavioral, and environmnetal acts that can have preventive, therapeutic, or palliative effects. concept code: Vascular disorders display: Vascular Disorder definition: Any deviation from the normal structure or function of the vascular system that is manifested by a characteristic set of symptoms and signs. ValueSet #d1e56008-vs status: Active compose Includes - System * http://example.org/nci.nih.gov/xml/owl/cadsr/form/form_design_identifier/3265657v2.0/question_identifier#3557869v2.0-cs CodeSystem #d1e57358-cs url: http://example.org/nci.nih.gov/xml/owl/cadsr/form/form_design_identifier/3265657v2.0/question_identifier#3557050v2.0-cs status: Active caseSensitive: true content: Complete concept code: 10000060 display: Abdominal distension definition: A disorder characterized by swelling of the abdomen. concept code: 10000081 display: Abdominal pain definition: A disorder characterized by a sensation of marked discomfort in the abdominal region. concept code: 10000486 display: Acidosis definition: A disorder characterized by abnormally high acidity (high hydrogen-ion concentration) of the blood and other body tissues. concept code: 10000521 display: Acoustic nerve disorder NOS definition: A disorder characterized by involvement of the acoustic nerve (eighth cranial nerve). concept code: 10000636 display: Activated partial thromboplastin time prolonged definition: An abnormal laboratory test result in which the partial thromboplastin time is found to be greater than the control value. As a possible indicator of coagulopathy, a prolonged partial thromboplastin time (PTT) may occur in a variety of diseases and disorders, both primary and related to treatment. concept code: 10001367 display: Adrenal insufficiency definition: A disorder that occurs when the adrenal cortex does not produce enough of the hormone cortisol and in some cases, the hormone aldosterone. It may be due to a disorder of the adrenal cortex as in Addison's disease or primary adrenal insufficiency. concept code: 10001409 display: Adult respiratory distress syndrome definition: A disorder characterized by progressive and life-threatening pulmonary distress in the absence of an underlying pulmonary condition, usually following major trauma or surgery. concept code: 10001497 display: Agitation definition: A disorder characterized by a state of restlessness associated with unpleasant feelings of irritability and tension. concept code: 10001540 display: Akathisia definition: A disorder characterized by an uncomfortable feeling of inner restlessness and inability to stay still; this is a side effect of some psychotropic drugs. concept code: 10001551 display: Alanine aminotransferase increased definition: A finding based on laboratory test results that indicate an increase in the level of alanine aminotransferase (ALT or SGPT) in the blood specimen. concept code: 10001598 display: Alcohol intolerance definition: A disorder characterized by an increase in sensitivity to the adverse effects of alcohol, which can include nasal congestion, skin flushes, heart dysrhythmias, nausea, vomiting, indigestion and headaches. concept code: 10001675 display: Alkaline phosphatase increased definition: A finding based on laboratory test results that indicate an increase in the level of alkaline phosphatase in a blood specimen. concept code: 10001680 display: Alkalosis definition: A disorder characterized by abnormally high alkalinity (low hydrogen-ion concentration) of the blood and other body tissues. concept code: 10001718 display: Allergic reaction definition: A disorder characterized by an adverse local or general response from exposure to an allergen. concept code: 10001723 display: Allergic rhinitis definition: A disorder characterized by an inflammation of the nasal mucous membranes caused by an IgE-mediated response to external allergens. The inflammation may also involve the mucous membranes of the sinuses, eyes, middle ear, and pharynx. Symptoms include sneezing, nasal congestion, rhinorrhea and itching. concept code: 10001760 display: Alopecia definition: A disorder characterized by a decrease in density of hair compared to normal for a given individual at a given age and body location. concept code: 10001949 display: Amnesia definition: A disorder characterized by systematic and extensive loss of memory. concept code: 10002156 display: Anal fistula definition: A disorder characterized by an abnormal communication between the opening in the anal canal to the perianal skin. concept code: 10002167 display: Anal pain definition: A disorder characterized by a sensation of marked discomfort in the anal region. concept code: 10002176 display: Anal stenosis definition: A disorder characterized by a narrowing of the lumen of the anal canal. concept code: 10002180 display: Anal ulcer definition: A disorder characterized by a circumscribed, inflammatory and necrotic erosive lesion on the mucosal surface of the anal canal. concept code: 10002218 display: Anaphylaxis definition: A disorder characterized by an acute inflammatory reaction resulting from the release of histamine and histamine-like substances from mast cells, causing a hypersensitivity immune response. Clinically, it presents with breathing difficulty, dizziness, hypotension, cyanosis and loss of consciousness and may lead to death. concept code: 10002272 display: Anemia definition: A disorder characterized by an reduction in the amount of hemoglobin in 100 ml of blood. Signs and symptoms of anemia may include pallor of the skin and mucous membranes, shortness of breath, palpitations of the heart, soft systolic murmurs, lethargy, and fatigability. concept code: 10002544 display: Ankle fracture definition: A finding of damage to the ankle joint characterized by a break in the continuity of the ankle bone. Symptoms include marked discomfort, swelling and difficulty moving the affected leg and foot. concept code: 10002646 display: Anorexia definition: A disorder characterized by a loss of appetite. concept code: 10002652 display: Anorgasmia definition: A disorder characterized by an inability to achieve orgasm. concept code: 10002855 display: Anxiety definition: A disorder characterized by apprehension of danger and dread accompanied by restlessness, tension, tachycardia, and dyspnea unattached to a clearly identifiable stimulus. concept code: 10002899 display: Aortic injury definition: A finding of damage to the aorta. concept code: 10002953 display: Aphonia definition: A disorder characterized by the inability to speak. It may result from injuries to the vocal cords or may be functional (psychogenic). concept code: 10002972 display: Apnea definition: A disorder characterized by cessation of breathing. concept code: 10003011 display: Appendicitis definition: A disorder characterized by acute inflammation to the vermiform appendix caused by a pathogenic agent. concept code: 10003012 display: Appendicitis perforated definition: A disorder characterized by acute inflammation to the vermiform appendix caused by a pathogenic agent with gangrenous changes resulting in the rupture of the appendiceal wall. The appendiceal wall rupture causes the release of inflammatory and bacterial contents from the appendiceal lumen into the abdominal cavity. concept code: 10003074 display: Arachnoiditis definition: A disorder characterized by inflammation of the arachnoid membrane and adjacent subarachnoid space. concept code: 10003162 display: Arterial injury definition: A finding of damage to an artery. concept code: 10003239 display: Arthralgia definition: A disorder characterized by a sensation of marked discomfort in a joint. concept code: 10003246 display: Arthritis definition: A disorder characterized by inflammation involving a joint. concept code: 10003445 display: Ascites definition: A disorder characterized by accumulation of serous or hemorrhagic fluid in the peritoneal cavity. concept code: 10003481 display: Aspartate aminotransferase increased definition: A finding based on laboratory test results that indicate an increase in the level of aspartate aminotransferase (AST or SGOT) in a blood specimen. concept code: 10003504 display: Aspiration definition: A disorder characterized by inhalation of solids or liquids into the lungs. concept code: 10003586 display: Asystole definition: A disorder characterized by a dysrhythmia without cardiac electrical activity. Typically, this is accompanied by cessation of the pumping function of the heart. concept code: 10003591 display: Ataxia definition: A disorder characterized by lack of coordination of muscle movements resulting in the impairment or inability to perform voluntary activities. concept code: 10003598 display: Atelectasis definition: A disorder characterized by the collapse of part or the entire lung. concept code: 10003658 display: Atrial fibrillation definition: A disorder characterized by a dysrhythmia without discernible P waves and an irregular ventricular response due to multiple reentry circuits. The rhythm disturbance originates above the ventricles. concept code: 10003662 display: Atrial flutter definition: A disorder characterized by a dysrhythmia with organized rhythmic atrial contractions with a rate of 200-300 beats per minute. The rhythm disturbance originates in the atria. concept code: 10003673 display: Atrioventricular block complete definition: A disorder characterized by a dysrhythmia with complete failure of atrial electrical impulse conduction through the AV node to the ventricles. concept code: 10003674 display: Atrioventricular block first degree definition: A disorder characterized by a dysrhythmia with a delay in the time required for the conduction of an electrical impulse through the atrioventricular (AV) node beyond 0.2 seconds; prolongation of the PR interval greater than 200 milliseconds. concept code: 10003883 display: Azoospermia definition: A disorder characterized by laboratory test results that indicate complete absence of spermatozoa in the semen. concept code: 10003988 display: Back pain definition: A disorder characterized by marked discomfort sensation in the back region. concept code: 10004665 display: Biliary fistula definition: A disorder characterized by an abnormal communication between the bile ducts and another organ or anatomic site. concept code: 10005047 display: Bladder infection definition: A disorder characterized by an infectious process involving the bladder. concept code: 10005265 display: Bloating definition: A disorder characterized by subject-reported feeling of uncomfortable fullness of the abdomen. concept code: 10005329 display: Blood and lymphatic system disorders - Other, specify definition: No Value Exists concept code: 10005332 display: Blood antidiuretic hormone abnormal definition: A finding based on laboratory test results that indicate abnormal levels of antidiuretic hormone in the blood specimen. concept code: 10005364 display: Blood bilirubin increased definition: A finding based on laboratory test results that indicate an abnormally high level of bilirubin in the blood. Excess bilirubin is associated with jaundice. concept code: 10005452 display: Blood corticotrophin decreased definition: A finding based on laboratory test results that indicate an decrease in levels of corticotrophin in a blood specimen. concept code: 10005561 display: Blood gonadotrophin abnormal definition: A finding based on laboratory test results that indicate abnormal levels of gonadotrophin hormone in a blood specimen. concept code: 10005778 display: Blood prolactin abnormal definition: A finding based on laboratory test results that indicate abnormal levels of prolactin hormone in a blood specimen. concept code: 10005886 display: Blurred vision definition: A disorder characterized by visual perception of unclear or fuzzy images. concept code: 10005901 display: Body odor definition: A disorder characterized by an abnormal body smell resulting from the growth of bacteria on the body. concept code: 10006002 display: Bone pain definition: A disorder characterized by marked discomfort sensation in the bones. concept code: 10006179 display: Breast atrophy definition: A disorder characterized by underdevelopment of the breast. concept code: 10006259 display: Breast infection definition: A disorder characterized by an infectious process involving the breast. concept code: 10006298 display: Breast pain definition: A disorder characterized by marked discomfort sensation in the breast region. concept code: 10006437 display: Bronchial fistula definition: A disorder characterized by an abnormal communication between the bronchus and another organ or anatomic site. concept code: 10006440 display: Bronchial obstruction definition: A disorder characterized by blockage of a bronchus passage, most often by bronchial secretions and exudates. concept code: 10006482 display: Bronchospasm definition: A disorder characterized by a sudden contraction of the smooth muscles of the bronchial wall. concept code: 10006504 display: Bruising definition: A finding of injury of the soft tissues or bone characterized by leakage of blood into surrounding tissues. concept code: 10006556 display: Bullous dermatitis definition: A disorder characterized by inflammation of the skin characterized by the presence of bullae which are filled with fluid. concept code: 10006634 display: Burn definition: A finding of impaired integrity to the anatomic site of an adverse thermal reaction. Burns can be caused by exposure to chemicals, direct heat, electricity, flames and radiation. The extent of damage depends on the length and intensity of exposure and time until provision of treatment. concept code: 10007196 display: Capillary leak syndrome definition: A disorder characterized by leakage of intravascular fluids into the extravascular space. This syndrome is observed in patients who demonstrate a state of generalized leaky capillaries following shock syndromes, low-flow states, ischemia-reperfusion injuries, toxemias, medications, or poisoning. It can lead to generalized edema and multiple organ failure. concept code: 10007515 display: Cardiac arrest definition: A disorder characterized by cessation of the pumping function of the heart. concept code: 10007541 display: Cardiac disorders - Other, specify definition: No Value Exists concept code: 10007612 display: Cardiac troponin I increased definition: A laboratory test result which indicates increased levels of cardiac troponin I in a biological specimen. concept code: 10007613 display: Cardiac troponin T increased definition: A laboratory test result which indicates increased levels of cardiac troponin T in a biological specimen. concept code: 10007739 display: Cataract definition: A disorder characterized by partial or complete opacity of the crystalline lens of one or both eyes. This results in a decrease in visual acuity and eventual blindness if untreated. concept code: 10007810 display: Catheter related infection definition: A disorder characterized by an infectious process that arises secondary to catheter use. concept code: 10007839 display: CD4 lymphocytes decreased definition: A finding based on laboratory test results that indicate an decrease in levels of CD4 lymphocytes in a blood specimen. concept code: 10008164 display: Cerebrospinal fluid leakage definition: A disorder characterized by loss of cerebrospinal fluid into the surrounding tissues. concept code: 10008330 display: Cervicitis infection definition: A disorder characterized by an infectious process involving the uterine cervix. concept code: 10008417 display: Cheilitis definition: A disorder characterized by inflammation of the lip. concept code: 10008481 display: Chest pain - cardiac definition: A disorder characterized by substernal discomfort due to insufficient myocardial oxygenation. concept code: 10008496 display: Chest wall pain definition: A disorder characterized by marked discomfort sensation in the chest wall region. concept code: 10008531 display: Chills definition: A disorder characterized by a sensation of cold that often marks a physiologic response to sweating after a fever. concept code: 10008612 display: Cholecystitis definition: A disorder characterized by inflammation involving the gallbladder. It may be associated with the presence of gallstones. concept code: 10008661 display: Cholesterol high definition: A finding based on laboratory test results that indicate higher than normal levels of cholesterol in a blood specimen. concept code: 10009845 display: Cognitive disturbance definition: A disorder characterized by a conspicuous change in cognitive function. concept code: 10009887 display: Colitis definition: A disorder characterized by inflammation of the colon. concept code: 10009995 display: Colonic fistula definition: A disorder characterized by an abnormal communication between the large intestine and another organ or anatomic site. concept code: 10009998 display: Colonic hemorrhage definition: A disorder characterized by bleeding from the colon. concept code: 10010000 display: Colonic obstruction definition: A disorder characterized by blockage of the normal flow of the intestinal contents in the colon. concept code: 10010001 display: Colonic perforation definition: A disorder characterized by a rupture in the colonic wall. concept code: 10010004 display: Colonic stenosis definition: A disorder characterized by a narrowing of the lumen of the colon. concept code: 10010006 display: Colonic ulcer definition: A disorder characterized by a circumscribed, inflammatory and necrotic erosive lesion on the mucosal surface of the colon. concept code: 10010250 display: Concentration impairment definition: A disorder characterized by a deterioration in the ability to concentrate. concept code: 10010276 display: Conduction disorder definition: A disorder characterized by pathological irregularities in the cardiac conduction system. concept code: 10010300 display: Confusion definition: A disorder characterized by a lack of clear and orderly thought and behavior. concept code: 10010331 display: Congenital, familial and genetic disorders - Other, specify definition: No Value Exists concept code: 10010741 display: Conjunctivitis definition: A disorder characterized by inflammation, swelling and redness to the conjunctiva of the eye. concept code: 10010742 display: Conjunctivitis infective definition: A disorder characterized by an infectious process involving the conjunctiva. Clinical manifestations include pink or red color in the eyes. concept code: 10010774 display: Constipation definition: A disorder characterized by irregular and infrequent or difficult evacuation of the bowels. concept code: 10010783 display: Constrictive pericarditis definition: A disorder characterized by a thickened and fibrotic pericardial sac; these fibrotic changes impede normal myocardial function by restricting myocardial muscle action. concept code: 10011224 display: Cough definition: A disorder characterized by sudden, often repetitive, spasmodic contraction of the thoracic cavity, resulting in violent release of air from the lungs and usually accompanied by a distinctive sound. concept code: 10011268 display: CPK increased definition: A finding based on laboratory test results that indicate an increase in levels of creatine phosphokinase in a blood specimen. concept code: 10011368 display: Creatinine increased definition: A finding based on laboratory test results that indicate increased levels of creatinine in a biological specimen. concept code: 10011655 display: Cushingoid definition: A disorder characterized by signs and symptoms that resemble Cushing's disease or syndrome: buffalo hump obesity, striations, adiposity, hypertension, diabetes, and osteoporosis, usually due to exogenous corticosteroids. concept code: 10011912 display: Death neonatal definition: A disorder characterized by cessation of life occurring during the first 28 days of life. concept code: 10011914 display: Death NOS definition: A cessation of life that cannot be attributed to a CTCAE term associated with Grade 5. concept code: 10012174 display: Dehydration definition: A disorder characterized by excessive loss of water from the body. It is usually caused by severe diarrhea, vomiting or diaphoresis. concept code: 10012205 display: Delayed puberty definition: A disorder characterized by unusually late sexual maturity. concept code: 10012218 display: Delirium definition: A disorder characterized by the acute and sudden development of confusion, illusions, movement changes, inattentiveness, agitation, and hallucinations. Usually, it is a reversible condition. concept code: 10012260 display: Delusions definition: A disorder characterized by false personal beliefs held contrary to reality, despite contradictory evidence and common sense. concept code: 10012318 display: Dental caries definition: A disorder characterized by the decay of a tooth, in which it becomes softened, discolored and/or porous. concept code: 10012373 display: Depressed level of consciousness definition: A disorder characterized by a decrease in ability to perceive and respond. concept code: 10012378 display: Depression definition: A disorder characterized by melancholic feelings of grief or unhappiness. concept code: 10012727 display: Diarrhea definition: A disorder characterized by frequent and watery bowel movements. concept code: 10013442 display: Disseminated intravascular coagulation definition: A disorder characterized by systemic pathological activation of blood clotting mechanisms which results in clot formation throughout the body. There is an increase in the risk of hemorrhage as the body is depleted of platelets and coagulation factors. concept code: 10013573 display: Dizziness definition: A disorder characterized by a disturbing sensation of lightheadedness, unsteadiness, giddiness, spinning or rocking. concept code: 10013774 display: Dry eye definition: A disorder characterized by dryness of the cornea and conjunctiva. concept code: 10013781 display: Dry mouth definition: A disorder characterized by reduced salivary flow in the oral cavity. concept code: 10013786 display: Dry skin definition: A disorder characterized by flaky and dull skin; the pores are generally fine, the texture is a papery thin texture. concept code: 10013828 display: Duodenal fistula definition: A disorder characterized by an abnormal communication between the duodenum and another organ or anatomic site. concept code: 10013830 display: Duodenal obstruction definition: A disorder characterized by blockage of the normal flow of stomach contents through the duodenum. concept code: 10013832 display: Duodenal perforation definition: A disorder characterized by a rupture in the duodenal wall. concept code: 10013836 display: Duodenal ulcer definition: A disorder characterized by a circumscribed, inflammatory and necrotic erosive lesion on the mucosal surface of the duodenal wall. concept code: 10013887 display: Dysarthria definition: A disorder characterized by slow and slurred speech resulting from an inability to coordinate the muscles used in speech. concept code: 10013911 display: Dysgeusia definition: A disorder characterized by abnormal sensual experience with the taste of foodstuffs; it can be related to a decrease in the sense of smell. concept code: 10013934 display: Dysmenorrhea definition: A disorder characterized by abnormally painful abdominal cramps during menses. concept code: 10013941 display: Dyspareunia definition: A disorder characterized by painful or difficult coitus. concept code: 10013946 display: Dyspepsia definition: A disorder characterized by an uncomfortable, often painful feeling in the stomach, resulting from impaired digestion. Symptoms include burning stomach, bloating, heartburn, nausea and vomiting. concept code: 10013950 display: Dysphagia definition: A disorder characterized by difficulty in swallowing. concept code: 10013951 display: Dysphasia definition: A disorder characterized by impairment of verbal communication skills, often resulting from brain damage. concept code: 10013963 display: Dyspnea definition: A disorder characterized by an uncomfortable sensation of difficulty breathing. concept code: 10013993 display: Ear and labyrinth disorders - Other, specify definition: No Value Exists concept code: 10014020 display: Ear pain definition: A disorder characterized by a sensation of marked discomfort in the ear. concept code: 10014217 display: Edema cerebral definition: A disorder characterized by swelling due to an excessive accumulation of fluid in the brain. concept code: 10014222 display: Edema face definition: A disorder characterized by swelling due to excessive fluid accumulation in facial tissues. concept code: 10014326 display: Ejaculation disorder definition: A disorder characterized by problems related to ejaculation. This category includes premature, delayed, retrograde and painful ejaculation. concept code: 10014383 display: Electrocardiogram QT corrected interval prolonged definition: A finding of a cardiac dysrhythmia characterized by an abnormally long corrected QT interval. concept code: 10014594 display: Encephalitis infection definition: A disorder characterized by an infectious process involving the brain tissue. concept code: 10014621 display: Encephalomyelitis infection definition: A disorder characterized by an infectious process involving the brain and spinal cord tissues. concept code: 10014625 display: Encephalopathy definition: A disorder characterized by a pathologic process involving the brain. concept code: 10014678 display: Endocarditis infective definition: A disorder characterized by an infectious process involving the endocardial layer of the heart. concept code: 10014698 display: Endocrine disorders - Other, specify definition: No Value Exists concept code: 10014801 display: Endophthalmitis definition: A disorder characterized by an infectious process involving the internal structures of the eye. concept code: 10014893 display: Enterocolitis definition: A disorder characterized by inflammation of the small and large intestines. concept code: 10015090 display: Epistaxis definition: A disorder characterized by bleeding from the nose. concept code: 10015218 display: Erythema multiforme definition: A disorder characterized by target lesions (a pink-red ring around a pale center). concept code: 10015277 display: Erythroderma definition: A disorder characterized by generalized inflammatory erythema and exfoliation. The inflammatory process involves > 90% of the body surface area. concept code: 10015384 display: Esophageal hemorrhage definition: A disorder characterized by bleeding from the esophagus. concept code: 10015387 display: Esophageal obstruction definition: A disorder characterized by blockage of the normal flow of the contents in the esophagus. concept code: 10015388 display: Esophageal pain definition: A disorder characterized by a sensation of marked discomfort in the esophageal region. concept code: 10015448 display: Esophageal stenosis definition: A disorder characterized by a narrowing of the lumen of the esophagus. concept code: 10015451 display: Esophageal ulcer definition: A disorder characterized by a circumscribed, inflammatory and necrotic erosive lesion on the mucosal surface of the esophageal wall. concept code: 10015453 display: Esophageal varices hemorrhage definition: A disorder characterized by bleeding from esophageal varices. concept code: 10015461 display: Esophagitis definition: A disorder characterized by inflammation of the esophageal wall. concept code: 10015533 display: Euphoria definition: A disorder characterized by an exaggerated feeling of well-being which is disproportionate to events and stimuli. concept code: 10015688 display: Exostosis definition: A disorder characterized by non-neoplastic overgrowth of bone. concept code: 10015829 display: Extraocular muscle paresis definition: A disorder characterized by incomplete paralysis of an extraocular muscle. concept code: 10015832 display: Extrapyramidal disorder definition: A disorder characterized by abnormal, repetitive, involuntary muscle movements, frenzied speech and extreme restlessness. concept code: 10015919 display: Eye disorders - Other, specify definition: No Value Exists concept code: 10015929 display: Eye infection definition: A disorder characterized by an infectious process involving the eye. concept code: 10015958 display: Eye pain definition: A disorder characterized by a sensation of marked discomfort in the eye. concept code: 10016059 display: Facial pain definition: A disorder characterized by a sensation of marked discomfort in the face. concept code: 10016173 display: Fall definition: A finding of sudden movement downward, usually resulting in injury. concept code: 10016241 display: Fat atrophy definition: A disorder characterized by shrinking of adipose tissue. concept code: 10016256 display: Fatigue definition: A disorder characterized by a state of generalized weakness with a pronounced inability to summon sufficient energy to accomplish daily activities. concept code: 10016288 display: Febrile neutropenia definition: A disorder characterized by a decrease in neutrophils associated with fever. concept code: 10016296 display: Fecal incontinence definition: A disorder characterized by inability to control the escape of stool from the rectum. concept code: 10016479 display: Fetal death definition: A disorder characterized by death in utero; failure of the product of conception to show evidence of respiration, heartbeat, or definite movement of a voluntary muscle after expulsion from the uterus, without possibility of resuscitation. concept code: 10016558 display: Fever definition: A disorder characterized by elevation of the body's temperature above the upper limit of normal. concept code: 10016596 display: Fibrinogen decreased definition: A finding based on laboratory test results that indicate an decrease in levels of fibrinogen in a blood specimen. concept code: 10016750 display: Flank pain definition: A disorder characterized by marked discomfort sensation on the lateral side of the body in the region below the ribs and above the hip. concept code: 10016757 display: Flashing lights definition: A disorder characterized by a sudden or brief burst of light. concept code: 10016766 display: Flatulence definition: A disorder characterized by a state of excessive gas in the alimentary canal. concept code: 10016778 display: Floaters definition: A disorder characterized by an individual seeing spots before their eyes. The spots are shadows of opaque cell fragments in the vitreous humor or lens. concept code: 10016791 display: Flu like symptoms definition: A disorder characterized by a group of symptoms similar to those observed in patients with the flu. It includes fever, chills, body aches, malaise, loss of appetite and dry cough. concept code: 10016825 display: Flushing definition: A disorder characterized by episodic reddening of the face. concept code: 10016987 display: Forced expiratory volume decreased definition: A finding based on test results that indicate a relative decrease in the fraction of the forced vital capacity that is exhaled in a specific number of seconds. concept code: 10017076 display: Fracture definition: A finding of traumatic injury to the bone in which the continuity of the bone is broken. concept code: 10017577 display: Gait disturbance definition: A disorder characterized by walking difficulties. concept code: 10017631 display: Gallbladder fistula definition: A disorder characterized by an abnormal communication between the gallbladder and another organ or anatomic site. concept code: 10017636 display: Gallbladder obstruction definition: A disorder characterized by blockage of the normal flow of the contents of the gallbladder. concept code: 10017638 display: Gallbladder pain definition: A disorder characterized by a sensation of marked discomfort in the gallbladder region. concept code: 10017639 display: Gallbladder perforation definition: A disorder characterized by a rupture in the gallbladder wall. concept code: 10017789 display: Gastric hemorrhage definition: A disorder characterized by bleeding from the gastric wall. concept code: 10017815 display: Gastric perforation definition: A disorder characterized by a rupture in the stomach wall. concept code: 10017822 display: Gastric ulcer definition: A disorder characterized by a circumscribed, inflammatory and necrotic erosive lesion on the mucosal surface of the stomach. concept code: 10017853 display: Gastritis definition: A disorder characterized by inflammation of the stomach. concept code: 10017877 display: Gastrointestinal fistula definition: A disorder characterized by an abnormal communication between any part of the gastrointestinal system and another organ or anatomic site. concept code: 10017947 display: Gastrointestinal disorders - Other, specify definition: No Value Exists concept code: 10017999 display: Gastrointestinal pain definition: A disorder characterized by a sensation of marked discomfort in the gastrointestinal region. concept code: 10018043 display: Gastroparesis definition: A disorder characterized by an incomplete paralysis of the muscles of the stomach wall resulting in delayed emptying of the gastric contents into the small intestine. concept code: 10018065 display: General disorders and administration site conditions - Other, specify definition: No Value Exists concept code: 10018146 display: Genital edema definition: A disorder characterized by swelling due to an excessive accumulation of fluid in the genitals. concept code: 10018286 display: Gingival pain definition: A disorder characterized by a sensation of marked discomfort in the gingival region. concept code: 10018304 display: Glaucoma definition: A disorder characterized by an increase in pressure in the eyeball due to obstruction of the aqueous humor outflow. concept code: 10018746 display: Growth accelerated definition: A disorder characterized by greater growth than expected for age. concept code: 10018748 display: Growth hormone abnormal definition: A finding based on laboratory test results that indicate abnormal levels of growth hormone in a biological specimen. concept code: 10018761 display: Growth suppression definition: A disorder characterized by of stature that is smaller than normal as expected for age. concept code: 10018784 display: Gum infection definition: A disorder characterized by an infectious process involving the gums. concept code: 10018801 display: Gynecomastia definition: A disorder characterized by excessive development of the breasts in males. concept code: 10019077 display: Hallucinations definition: A disorder characterized by a false sensory perception in the absence of an external stimulus. concept code: 10019150 display: Haptoglobin decreased definition: A finding based on laboratory test results that indicate an decrease in levels of haptoglobin in a blood specimen. concept code: 10019211 display: Headache definition: A disorder characterized by a sensation of marked discomfort in various parts of the head, not confined to the area of distribution of any nerve. concept code: 10019245 display: Hearing impaired definition: A disorder characterized by partial or complete loss of the ability to detect or understand sounds resulting from damage to ear structures. concept code: 10019279 display: Heart failure definition: A disorder characterized by the inability of the heart to pump blood at an adequate volume to meet tissue metabolic requirements, or, the ability to do so only at an elevation in the filling pressure. concept code: 10019428 display: Hematoma definition: A disorder characterized by a localized collection of blood, usually clotted, in an organ, space, or tissue, due to a break in the wall of a blood vessel. concept code: 10019450 display: Hematuria definition: A disorder characterized by laboratory test results that indicate blood in the urine. concept code: 10019489 display: Hemoglobinuria definition: A disorder characterized by laboratory test results that indicate the presence of free hemoglobin in the urine. concept code: 10019491 display: Hemolysis definition: A disorder characterized by laboratory test results that indicate widespread erythrocyte cell membrane destruction. concept code: 10019515 display: Hemolytic uremic syndrome definition: A disorder characterized by a form of thrombotic microangiopathy with renal failure, hemolytic anemia, and severe thrombocytopenia. concept code: 10019611 display: Hemorrhoids definition: A disorder characterized by the presence of dilated veins in the rectum and surrounding area. concept code: 10019663 display: Hepatic failure definition: A disorder characterized by the inability of the liver to metabolize chemicals in the body. Laboratory test results reveal abnormal plasma levels of ammonia, bilirubin, lactic dehydrogenase, and alkaline phosphatase. concept code: 10019678 display: Hepatic hemorrhage definition: A disorder characterized by bleeding from the liver. concept code: 10019692 display: Hepatic necrosis definition: A disorder characterized by a necrotic process occurring in the hepatic parenchyma. concept code: 10019705 display: Hepatic pain definition: A disorder characterized by a sensation of marked discomfort in the liver region. concept code: 10019799 display: Hepatitis viral definition: A disorder characterized by a viral pathologic process involving the liver parenchyma. concept code: 10019805 display: Hepatobiliary disorders - Other, specify definition: No Value Exists concept code: 10020039 display: Hiccups definition: A disorder characterized by repeated gulp sounds that result from an involuntary opening and closing of the glottis. This is attributed to a spasm of the diaphragm. concept code: 10020100 display: Hip fracture definition: A finding of traumatic injury to the hip in which the continuity of either the femoral head, femoral neck, intertrochanteric or subtrochanteric regions is broken. concept code: 10020112 display: Hirsutism definition: A disorder characterized by the presence of excess hair growth in women in anatomic sites where growth is considered to be a secondary male characteristic and under androgen control (beard, moustache, chest, abdomen) concept code: 10020201 display: Hoarseness definition: A disorder characterized by harsh and raspy voice arising from or spreading to the larynx. concept code: 10020407 display: Hot flashes definition: A disorder characterized by an uncomfortable and temporary sensation of intense body warmth, flushing, sometimes accompanied by sweating upon cooling. concept code: 10020508 display: Hydrocephalus definition: A disorder characterized by an abnormal increase of cerebrospinal fluid in the ventricles of the brain. concept code: 10020587 display: Hypercalcemia definition: A disorder characterized by laboratory test results that indicate an elevation in the concentration of calcium in blood. concept code: 10020639 display: Hyperglycemia definition: A disorder characterized by laboratory test results that indicate an elevation in the concentration of blood sugar. It is usually an indication of diabetes mellitus or glucose intolerance. concept code: 10020642 display: Hyperhidrosis definition: A disorder characterized by excessive perspiration. concept code: 10020647 display: Hyperkalemia definition: A disorder characterized by laboratory test results that indicate an elevation in the concentration of potassium in the blood; associated with kidney failure or sometimes with the use of diuretic drugs. concept code: 10020670 display: Hypermagnesemia definition: A disorder characterized by laboratory test results that indicate an elevation in the concentration of magnesium in the blood. concept code: 10020680 display: Hypernatremia definition: A disorder characterized by laboratory test results that indicate an elevation in the concentration of sodium in the blood. concept code: 10020705 display: Hyperparathyroidism definition: A disorder characterized by an increase in production of parathyroid hormone by the parathyroid glands. This results in hypercalcemia (abnormally high levels of calcium in the blood). concept code: 10020765 display: Hypersomnia definition: A disorder characterized by characterized by excessive sleepiness during the daytime. concept code: 10020772 display: Hypertension definition: A disorder characterized by a pathological increase in blood pressure; a repeatedly elevation in the blood pressure exceeding 140 over 90 mm Hg. concept code: 10020850 display: Hyperthyroidism definition: A disorder characterized by excessive levels of thyroid hormone in the body. Common causes include an overactive thyroid gland or thyroid hormone overdose. concept code: 10020864 display: Hypertrichosis definition: A disorder characterized by hair density or length beyond the accepted limits of normal in a particular body region, for a particular age or race. concept code: 10020870 display: Hypertriglyceridemia definition: A disorder characterized by laboratory test results that indicate an elevation in the concentration of triglyceride concentration in the blood. concept code: 10020907 display: Hyperuricemia definition: A disorder characterized by laboratory test results that indicate an elevation in the concentration of uric acid. concept code: 10020943 display: Hypoalbuminemia definition: A disorder characterized by laboratory test results that indicate a low concentration of albumin in the blood. concept code: 10020949 display: Hypocalcemia definition: A disorder characterized by laboratory test results that indicate a low concentration of calcium in the blood. concept code: 10021005 display: Hypoglycemia definition: A disorder characterized by laboratory test results that indicate a low concentration of glucose in the blood. concept code: 10021013 display: Hypohidrosis definition: A disorder characterized by reduced sweating. concept code: 10021018 display: Hypokalemia definition: A disorder characterized by laboratory test results that indicate a low concentration of potassium in the blood. concept code: 10021028 display: Hypomagnesemia definition: A disorder characterized by laboratory test results that indicate a low concentration of magnesium in the blood. concept code: 10021038 display: Hyponatremia definition: A disorder characterized by laboratory test results that indicate a low concentration of sodium in the blood. concept code: 10021041 display: Hypoparathyroidism definition: A disorder characterized by a decrease in production of parathyroid hormone by the parathyroid glands. concept code: 10021059 display: Hypophosphatemia definition: A disorder characterized by laboratory test results that indicate a low concentration of phosphates in the blood. concept code: 10021097 display: Hypotension definition: A disorder characterized by a blood pressure that is below the normal expected for an individual in a given environment. concept code: 10021113 display: Hypothermia definition: A disorder characterized by an abnormally low body temperature. Treatment is required when the body temperature is 35C (95F) or below. concept code: 10021114 display: Hypothyroidism definition: A disorder characterized by a decrease in production of thyroid hormone by the thyroid gland. concept code: 10021143 display: Hypoxia definition: A disorder characterized by a decrease in the level of oxygen in the body. concept code: 10021305 display: Ileal perforation definition: A disorder characterized by a rupture in the ileal wall. concept code: 10021307 display: Ileal stenosis definition: A disorder characterized by a narrowing of the lumen of the ileum. concept code: 10021309 display: Ileal ulcer definition: A disorder characterized by a circumscribed, inflammatory and necrotic erosive lesion on the mucosal surface of the ileum. concept code: 10021328 display: Ileus definition: A disorder characterized by failure of the ileum to transport intestinal contents. concept code: 10021428 display: Immune system disorders - Other, specify definition: No Value Exists concept code: 10021881 display: Infections and infestations - Other, specify definition: No Value Exists concept code: 10021918 display: Infective myositis definition: A disorder characterized by an infectious process involving the skeletal muscles. concept code: 10022095 display: Injection site reaction definition: A disorder characterized by an intense adverse reaction (usually immunologic) developing at the site of an injection. concept code: 10022117 display: Injury, poisoning and procedural complications - Other, specify definition: No Value Exists concept code: 10022161 display: Injury to carotid artery definition: A finding of damage to the carotid artery. concept code: 10022213 display: Injury to inferior vena cava definition: A finding of damage to the inferior vena cava. concept code: 10022356 display: Injury to superior vena cava definition: A finding of damage to the superior vena cava. concept code: 10022402 display: INR increased definition: A finding based on laboratory test results that indicate an increase in the ratio of the patient's prothrombin time to a control sample in the blood. concept code: 10022437 display: Insomnia definition: A disorder characterized by difficulty in falling asleep and/or remaining asleep. concept code: 10022763 display: Intracranial hemorrhage definition: A disorder characterized by bleeding from the cranium. concept code: 10022891 display: Investigations - Other, specify definition: No Value Exists concept code: 10022992 display: Irregular menstruation definition: A disorder characterized by irregular cycle or duration of menses. concept code: 10022998 display: Irritability definition: A disorder characterized by an abnormal responsiveness to stimuli or physiological arousal; may be in response to pain, fright, a drug, an emotional situation or a medical condition. concept code: 10023030 display: Ischemia cerebrovascular definition: A disorder characterized by a decrease or absence of blood supply to the brain caused by obstruction (thrombosis or embolism) of an artery resulting in neurological damage. concept code: 10023174 display: Jejunal perforation definition: A disorder characterized by a rupture in the jejunal wall. concept code: 10023176 display: Jejunal stenosis definition: A disorder characterized by a narrowing of the lumen of the jejunum. concept code: 10023177 display: Jejunal ulcer definition: A disorder characterized by a circumscribed, inflammatory and necrotic erosive lesion on the mucosal surface of the jejunum. concept code: 10023215 display: Joint effusion definition: A disorder characterized by excessive fluid in a joint, usually as a result of joint inflammation. concept code: 10023216 display: Joint infection definition: A disorder characterized by an infectious process involving a joint. concept code: 10023332 display: Keratitis definition: A disorder characterized by inflammation to the cornea of the eye. concept code: 10023424 display: Kidney infection definition: A disorder characterized by an infectious process involving the kidney. concept code: 10023509 display: Kyphosis definition: A disorder characterized by an abnormal increase in the curvature of the thoracic portion of the spine. concept code: 10023838 display: Laryngeal edema definition: A disorder characterized by swelling due to an excessive accumulation of fluid in the larynx. concept code: 10023862 display: Laryngeal stenosis definition: A disorder characterized by a narrowing of the laryngeal airway. concept code: 10023874 display: Laryngitis definition: A disorder characterized by an inflammatory process involving the larynx. concept code: 10023891 display: Laryngospasm definition: A disorder characterized by paroxysmal spasmodic muscular contraction of the vocal cords. concept code: 10024264 display: Lethargy definition: A disorder characterized by a decrease in consciousness characterized by mental and physical inertness. concept code: 10024378 display: Leukocytosis definition: A disorder characterized by laboratory test results that indicate an increased number of white blood cells in the blood. concept code: 10024382 display: Leukoencephalopathy definition: A disorder characterized by diffuse reactive astrocytosis with multiple areas of necrotic foci without inflammation. concept code: 10024419 display: Libido decreased definition: A disorder characterized by a decrease in sexual desire. concept code: 10024421 display: Libido increased definition: A disorder characterized by an increase in sexual desire. concept code: 10024561 display: Lip pain definition: A disorder characterized by a sensation of marked discomfort of the lip. concept code: 10024574 display: Lipase increased definition: A finding based on laboratory test results that indicate an increase in the level of lipase in a biological specimen. concept code: 10024842 display: Lordosis definition: A disorder characterized by an abnormal increase in the curvature of the lumbar portion of the spine. concept code: 10025182 display: Lymph node pain definition: A disorder characterized by a sensation of marked discomfort in a lymph node. concept code: 10025233 display: Lymphedema definition: A disorder characterized by excessive fluid collection in tissues that causes swelling. concept code: 10025256 display: Lymphocyte count decreased definition: A finding based on laboratory test results that indicate a decrease in number of lymphocytes in a blood specimen. concept code: 10025258 display: Lymphocyte count increased definition: A finding based on laboratory test results that indicate an abnormal increase in the number of lymphocytes in the blood, effusions or bone marrow. concept code: 10025476 display: Malabsorption definition: A disorder characterized by inadequate absorption of nutrients in the small intestine. Symptoms include abdominal marked discomfort, bloating and diarrhea. concept code: 10025482 display: Malaise definition: A disorder characterized by a feeling of general discomfort or uneasiness, an out-of-sorts feeling. concept code: 10026749 display: Mania definition: A disorder characterized by excitement of psychotic proportions manifested by mental and physical hyperactivity, disorganization of behavior and elevation of mood. concept code: 10027175 display: Memory impairment definition: A disorder characterized by a deterioration in memory function. concept code: 10027198 display: Meningismus definition: A disorder characterized by neck stiffness, headache, and photophobia resulting from irritation of the cerebral meninges. concept code: 10027199 display: Meningitis definition: A disorder characterized by acute inflammation of the meninges of the brain and/or spinal cord. concept code: 10027308 display: Menopause definition: A disorder characterized by the permanent cessation of menses, usually defined by 12 consecutive months of amenorrhea in a woman over 45 years of age. concept code: 10027313 display: Menorrhagia definition: A disorder characterized by abnormally heavy vaginal bleeding during menses. concept code: 10027433 display: Metabolism and nutrition disorders - Other, specify definition: No Value Exists concept code: 10027786 display: Mobitz (type) II atrioventricular block definition: A disorder characterized by a dysrhythmia with relatively constant PR interval prior to the block of an atrial impulse. This is the result of intermittent failure of atrial electrical impulse conduction through the atrioventricular (AV) node to the ventricles. concept code: 10027787 display: Mobitz type I definition: A disorder characterized by a dysrhythmia with a progressively lengthening PR interval prior to the blocking of an atrial impulse. This is the result of intermittent failure of atrial electrical impulse conduction through the atrioventricular (AV) node to the ventricles. concept code: 10028041 display: Movements involuntary definition: A disorder characterized by uncontrolled and purposeless movements. concept code: 10028130 display: Mucositis oral definition: A disorder characterized by inflammation of the oral mucosal. concept code: 10028154 display: Multi-organ failure definition: A disorder characterized by progressive deterioration of the lungs, liver, kidney and clotting mechanisms. concept code: 10028395 display: Musculoskeletal and connective tissue disorder - Other, specify definition: No Value Exists concept code: 10028411 display: Myalgia definition: A disorder characterized by marked discomfort sensation originating from a muscle or group of muscles. concept code: 10028524 display: Myelitis definition: A disorder characterized by inflammation involving the spinal cord. Symptoms include weakness, paresthesia, sensory loss, marked discomfort and incontinence. concept code: 10028533 display: Myelodysplastic syndrome definition: A disorder characterized by insufficiently healthy hematapoietic cell production by the bone marrow. concept code: 10028596 display: Myocardial infarction definition: A disorder characterized by gross necrosis of the myocardium; this is due to an interruption of blood supply to the area. concept code: 10028606 display: Myocarditis definition: A disorder characterized by inflammation of the muscle tissue of the heart. concept code: 10028653 display: Myositis definition: A disorder characterized by inflammation involving the skeletal muscles. concept code: 10028691 display: Nail discoloration definition: A disorder characterized by a change in the color of the nail plate. concept code: 10028735 display: Nasal congestion definition: A disorder characterized by obstruction of the nasal passage due to mucosal edema. concept code: 10028813 display: Nausea definition: A disorder characterized by a queasy sensation and/or the urge to vomit. concept code: 10028836 display: Neck pain definition: A disorder characterized by marked discomfort sensation in the neck area. concept code: 10029104 display: Neoplasms benign, malignant and unspecified (incl cysts and polyps) - Other, specify definition: No Value Exists concept code: 10029205 display: Nervous system disorders - Other, specify definition: No Value Exists concept code: 10029223 display: Neuralgia definition: A disorder characterized by intense painful sensation along a nerve or group of nerves. concept code: 10029366 display: Neutrophil count decreased definition: A finding based on laboratory test results that indicate a decrease in number of neutrophils in a blood specimen. concept code: 10029404 display: Night blindness definition: A disorder characterized by an inability to see clearly in dim light. concept code: 10029864 display: Nystagmus definition: A disorder characterized by involuntary movements of the eyeballs. concept code: 10029883 display: Obesity definition: A disorder characterized by having a high amount of body fat. concept code: 10029957 display: Obstruction gastric definition: A disorder characterized by blockage of the normal flow of the contents in the stomach. concept code: 10030300 display: Oligospermia definition: A disorder characterized by a decrease in the number of spermatozoa in the semen. concept code: 10030980 display: Oral hemorrhage definition: A disorder characterized by bleeding from the mouth. concept code: 10031009 display: Oral pain definition: A disorder characterized by a sensation of marked discomfort in the mouth, tongue or lips. concept code: 10031282 display: Osteoporosis definition: A disorder characterized by reduced bone mass, with a decrease in cortical thickness and in the number and size of the trabeculae of cancellous bone (but normal chemical composition), resulting in increased fracture incidence. concept code: 10033072 display: Otitis externa definition: A disorder characterized by an infectious process involving the outer ear and ear canal. Contributory factors include excessive water exposure (swimmer's ear infection) and cuts in the ear canal. Symptoms include fullness, itching, swelling and marked discomfort in the ear and ear drainage. concept code: 10033078 display: Otitis media definition: A disorder characterized by an infectious process involving the middle ear. concept code: 10033279 display: Ovarian rupture definition: A disorder characterized by tearing or disruption of the ovarian tissue. concept code: 10033314 display: Ovulation pain definition: A disorder characterized by marked discomfort sensation in one side of the abdomen between menstrual cycles, around the time of the discharge of the ovum from the ovarian follicle. concept code: 10033371 display: Pain definition: A disorder characterized by the sensation of marked discomfort, distress or agony. concept code: 10033425 display: Pain in extremity definition: A disorder characterized by marked discomfort sensation in the upper or lower extremities. concept code: 10033474 display: Pain of skin definition: A disorder characterized by marked discomfort sensation in the skin. concept code: 10033557 display: Palpitations definition: A disorder characterized by an unpleasant sensation of irregular and/or forceful beating of the heart. concept code: 10033626 display: Pancreatic hemorrhage definition: A disorder characterized by bleeding from the pancreas. concept code: 10033645 display: Pancreatitis definition: A disorder characterized by inflammation of the pancreas. concept code: 10033703 display: Papilledema definition: A disorder characterized by swelling around the optic disc. concept code: 10033987 display: Paresthesia definition: A disorder characterized by functional disturbances of sensory neurons resulting in abnormal cutaneous sensations of tingling, numbness, pressure, cold, and warmth that are experienced in the absence of a stimulus. concept code: 10034016 display: Paronychia definition: A disorder characterized by an infectious process involving the soft tissues around the nail. concept code: 10034040 display: Paroxysmal atrial tachycardia definition: A disorder characterized by a dysrhythmia with abrupt onset and sudden termination of atrial contractions with a rate of 150-250 beats per minute. The rhythm disturbance originates in the atria. concept code: 10034263 display: Pelvic pain definition: A disorder characterized by marked discomfort sensation in the pelvis. concept code: 10034310 display: Penile pain definition: A disorder characterized by marked discomfort sensation in the penis. concept code: 10034405 display: Perforation bile duct definition: A disorder characterized by a rupture in the wall of the extrahepatic or intrahepatic bile duct. concept code: 10034474 display: Pericardial effusion definition: A disorder characterized by fluid collection within the pericardial sac, usually due to inflammation. concept code: 10034484 display: Pericarditis definition: A disorder characterized by irritation to the layers of the pericardium (the protective sac around the heart). concept code: 10034536 display: Periodontal disease definition: A disorder in the gingival tissue around the teeth. concept code: 10034578 display: Peripheral ischemia definition: A disorder characterized by impaired circulation to an extremity. concept code: 10034580 display: Peripheral motor neuropathy definition: A disorder characterized by inflammation or degeneration of the peripheral motor nerves. concept code: 10034620 display: Peripheral sensory neuropathy definition: A disorder characterized by inflammation or degeneration of the peripheral sensory nerves. concept code: 10034719 display: Personality change definition: A disorder characterized by a conspicuous change in a person's behavior and thinking. concept code: 10034825 display: Pharyngeal fistula definition: A disorder characterized by an abnormal communication between the pharynx and another organ or anatomic site. concept code: 10034835 display: Pharyngitis definition: A disorder characterized by inflammation of the throat. concept code: 10034844 display: Pharyngolaryngeal pain definition: A disorder characterized by marked discomfort sensation in the pharyngolaryngeal region. concept code: 10034879 display: Phlebitis definition: A disorder characterized by inflammation of the wall of a vein. concept code: 10034960 display: Photophobia definition: A disorder characterized by fear and avoidance of light. concept code: 10034966 display: Photosensitivity definition: A disorder characterized by an increase in sensitivity of the skin to light. concept code: 10035528 display: Platelet count decreased definition: A finding based on laboratory test results that indicate a decrease in number of platelets in a blood specimen. concept code: 10035598 display: Pleural effusion definition: A disorder characterized by an increase in amounts of fluid within the pleural cavity. Symptoms include shortness of breath, cough and marked chest discomfort. concept code: 10035623 display: Pleuritic pain definition: A disorder characterized by marked discomfort sensation in the pleura. concept code: 10035742 display: Pneumonitis definition: A disorder characterized by inflammation focally or diffusely affecting the lung parenchyma. concept code: 10035759 display: Pneumothorax definition: A disorder characterized by abnormal presence of air in the pleural cavity resulting in the collapse of the lung. concept code: 10036200 display: Portal hypertension definition: A disorder characterized by an increase in blood pressure in the portal venous system. concept code: 10036206 display: Portal vein thrombosis definition: A disorder characterized by the formation of a thrombus (blood clot) in the portal vein. concept code: 10036402 display: Postnasal drip definition: A disorder characterized by excessive mucous secretion in the back of the nasal cavity or throat, causing sore throat and/or coughing. concept code: 10036585 display: Pregnancy, puerperium and perinatal conditions - Other, specify definition: No Value Exists concept code: 10036595 display: Premature delivery definition: A disorder characterized by delivery of a viable infant before the normal end of gestation. Typically, viability is achievable between the twentieth and thirty-seventh week of gestation. concept code: 10036601 display: Premature menopause definition: A disorder characterized by ovarian failure before the age of 40. Symptoms include hot flashes, night sweats, mood swings and a decrease in sex drive. concept code: 10036653 display: Presyncope definition: A disorder characterized by an episode of lightheadedness and dizziness which may precede an episode of syncope. concept code: 10036774 display: Proctitis definition: A disorder characterized by inflammation of the rectum. concept code: 10036790 display: Productive cough definition: A disorder characterized by expectorated secretions upon coughing. concept code: 10036968 display: Prostatic pain definition: A disorder characterized by a sensation of marked discomfort in the prostate gland. concept code: 10037032 display: Proteinuria definition: A disorder characterized by laboratory test results that indicate the presence of excessive protein in the urine. It is predominantly albumin, but also globulin. concept code: 10037087 display: Pruritus definition: A disorder characterized by an intense itching sensation. concept code: 10037175 display: Psychiatric disorders - Other, specify definition: No Value Exists concept code: 10037234 display: Psychosis definition: A disorder characterized by personality change, impaired functioning, and loss of touch with reality. It may be a manifestation of schizophrenia, bipolar disorder or brain tumor. concept code: 10037375 display: Pulmonary edema definition: A disorder characterized by accumulation of fluid in the lung tissues that causes a disturbance of the gas exchange that may lead to respiratory failure. concept code: 10037383 display: Pulmonary fibrosis definition: A disorder characterized by the replacement of the lung tissue by connective tissue, leading to progressive dyspnea, respiratory failure or right heart failure. concept code: 10037400 display: Pulmonary hypertension definition: A disorder characterized by an increase in pressure within the pulmonary circulation due to lung or heart disorder. concept code: 10037549 display: Purpura definition: A disorder characterized by hemorrhagic areas of the skin and mucous membrane. Newer lesions appear reddish in color. Older lesions are usually a darker purple color and eventually become a brownish-yellow color. concept code: 10037767 display: Radiation recall reaction (dermatologic) definition: A finding of acute skin inflammatory reaction caused by drugs, especially chemotherapeutic agents, for weeks or months following radiotherapy. The inflammatory reaction is confined to the previously irradiated skin and the symptoms disappear after the removal of the pharmaceutical agent. concept code: 10037847 display: Rash acneiform definition: A disorder characterized by an eruption of papules and pustules, typically appearing in face, scalp, upper chest and back. concept code: 10037868 display: Rash maculo-papular definition: A disorder characterized by the presence of macules (flat) and papules (elevated). Also known as morbillform rash, it is one of the most common cutaneous adverse events, frequently affecting the upper trunk, spreading centripetally and associated with pruritus. concept code: 10037888 display: Rash pustular definition: A disorder characterized by a circumscribed and elevated skin lesion filled with pus. concept code: 10038062 display: Rectal fistula definition: A disorder characterized by an abnormal communication between the rectum and another organ or anatomic site. concept code: 10038064 display: Rectal hemorrhage definition: A disorder characterized by bleeding from the rectal wall and discharged from the anus. concept code: 10038072 display: Rectal pain definition: A disorder characterized by a sensation of marked discomfort in the rectal region. concept code: 10038073 display: Rectal perforation definition: A disorder characterized by a rupture in the rectal wall. concept code: 10038079 display: Rectal stenosis definition: A disorder characterized by a narrowing of the lumen of the rectum. concept code: 10038080 display: Rectal ulcer definition: A disorder characterized by a circumscribed, inflammatory and necrotic erosive lesion on the mucosal surface of the rectum. concept code: 10038130 display: Recurrent laryngeal nerve palsy definition: A disorder characterized by paralysis of the recurrent laryngeal nerve. concept code: 10038359 display: Renal and urinary disorders - Other, specify definition: No Value Exists concept code: 10038385 display: Renal calculi definition: A disorder characterized by the formation of crystals in the pelvis of the kidney. concept code: 10038419 display: Renal colic definition: A disorder characterized by paroxysmal and severe flank marked discomfort radiating to the inguinal area. Often, the cause is the passage of kidney stones. concept code: 10038463 display: Renal hemorrhage definition: A disorder characterized by bleeding from the kidney. concept code: 10038604 display: Reproductive system and breast disorders - Other, specify definition: No Value Exists concept code: 10038695 display: Respiratory failure definition: A disorder characterized by impaired gas exchange by the respiratory system resulting in hypoxemia and a decrease in oxygenation of the tissues that may be associated with an increase in arterial levels of carbon dioxide. concept code: 10038738 display: Respiratory, thoracic and mediastinal disorders - Other, specify definition: No Value Exists concept code: 10038743 display: Restlessness definition: A disorder characterized by an inability to rest, relax or be still. concept code: 10038748 display: Restrictive cardiomyopathy definition: A disorder characterized by an inability of the ventricles to fill with blood because the myocardium (heart muscle) stiffens and loses its flexibility. concept code: 10038848 display: Retinal detachment definition: A disorder characterized by the separation of the inner retina layers from the underlying pigment epithelium. concept code: 10038897 display: Retinal tear definition: A disorder characterized by a small laceration of the retina, this occurs when the vitreous separates from the retina. Symptoms include flashes and floaters. concept code: 10038901 display: Retinal vascular disorder definition: A disorder characterized by pathological retinal blood vessels that adversely affects vision. concept code: 10038921 display: Retinoic acid syndrome definition: A disorder characterized by weight gain, dyspnea, pleural and pericardial effusions, leukocytosis and/or renal failure originally described in patients treated with all-trans retinoic acid. concept code: 10038923 display: Retinopathy definition: A disorder involving the retina. concept code: 10038981 display: Retroperitoneal hemorrhage definition: A disorder characterized by bleeding from the retroperitoneal area. concept code: 10039411 display: Salivary gland fistula definition: A disorder characterized by an abnormal communication between a salivary gland and another organ or anatomic site. concept code: 10039413 display: Salivary gland infection definition: A disorder characterized by an infectious process involving the salivary gland. concept code: 10039722 display: Scoliosis definition: A disorder characterized by a malformed, lateral curvature of the spine. concept code: 10039757 display: Scrotal pain definition: A disorder characterized by marked discomfort sensation in the scrotal area. concept code: 10039906 display: Seizure definition: A disorder characterized by a sudden, involuntary skeletal muscular contractions of cerebral or brain stem origin. concept code: 10040047 display: Sepsis definition: A disorder characterized by the presence of pathogenic microorganisms in the blood stream that cause a rapidly progressing systemic reaction that may lead to shock. concept code: 10040102 display: Seroma definition: A finding of tumor-like collection of serum in the tissues. concept code: 10040139 display: Serum amylase increased definition: A finding based on laboratory test results that indicate an increase in the levels of amylase in a serum specimen. concept code: 10040400 display: Serum sickness definition: A disorder characterized by a delayed-type hypersensitivity reaction to foreign proteins derived from an animal serum. It occurs approximately six to twenty-one days following the administration of the foreign antigen. Symptoms include fever, arthralgias, myalgias, skin eruptions, lymphadenopathy, chest marked discomfort and dyspnea. concept code: 10040639 display: Sick sinus syndrome definition: A disorder characterized by a dysrhythmia with alternating periods of bradycardia and atrial tachycardia accompanied by syncope, fatigue and dizziness. concept code: 10040741 display: Sinus bradycardia definition: A disorder characterized by a dysrhythmia with a heart rate less than 60 beats per minute that originates in the sinus node. concept code: 10040747 display: Sinus pain definition: A disorder characterized by marked discomfort in the face, between the eyes, or upper teeth originating from the sinuses. concept code: 10040752 display: Sinus tachycardia definition: A disorder characterized by a dysrhythmia with a heart rate greater than 100 beats per minute that originates in the sinus node. concept code: 10040753 display: Sinusitis definition: A disorder characterized by an infectious process involving the mucous membranes of the paranasal sinuses. concept code: 10040785 display: Skin and subcutaneous tissue disorders - Other, specify definition: No Value Exists concept code: 10040799 display: Skin atrophy definition: A disorder characterized by the degeneration and thinning of the epidermis and dermis. concept code: 10040865 display: Skin hyperpigmentation definition: A disorder characterized by darkening of the skin due to excessive melanin deposition. concept code: 10040868 display: Skin hypopigmentation definition: A disorder characterized by loss of skin pigment. concept code: 10040872 display: Skin infection definition: A disorder characterized by an infectious process involving the skin. concept code: 10040947 display: Skin ulceration definition: A disorder characterized by circumscribed, inflammatory and necrotic erosive lesion on the skin. concept code: 10040975 display: Sleep apnea definition: A disorder characterized by cessation of breathing for short periods during sleep. concept code: 10041101 display: Small intestinal obstruction definition: A disorder characterized by blockage of the normal flow of the intestinal contents. concept code: 10041103 display: Small intestinal perforation definition: A disorder characterized by a rupture in the small intestine wall. concept code: 10041133 display: Small intestine ulcer definition: A disorder characterized by a circumscribed, inflammatory and necrotic erosive lesion on the mucosal surface of the small intestine. concept code: 10041232 display: Sneezing definition: A disorder characterized by the involuntary expulsion of air from the nose. concept code: 10041244 display: Social circumstances - Other, specify definition: No Value Exists concept code: 10041349 display: Somnolence definition: A disorder characterized by characterized by excessive sleepiness and drowsiness. concept code: 10041367 display: Sore throat definition: A disorder characterized by of marked discomfort in the throat concept code: 10041416 display: Spasticity definition: A disorder characterized by increased involuntary muscle tone that affects the regions interfering with voluntary movement. It results in gait, movement, and speech disturbances. concept code: 10041569 display: Spinal fracture definition: A finding of traumatic injury to the spine in which the continuity of a vertebral bone is broken. concept code: 10041633 display: Spleen disorder definition: A disorder of the spleen. concept code: 10042033 display: Stevens-Johnson syndrome definition: A disorder characterized by less than 10% total body skin area separation of dermis. The syndrome is thought to be a hypersensitivity complex affecting the skin and the mucous membranes. concept code: 10042112 display: Stomach pain definition: A disorder characterized by a sensation of marked discomfort in the stomach. concept code: 10042127 display: Stomal ulcer definition: A disorder characterized by a circumscribed, inflammatory and necrotic erosive lesion on the jejunal mucosal surface close to the anastomosis site following a gastroenterostomy procedure. concept code: 10042241 display: Stridor definition: A disorder characterized by a high pitched breathing sound due to laryngeal or upper airway obstruction. concept code: 10042244 display: Stroke definition: A disorder characterized by a sudden loss of sensory function due to an intracranial vascular event. concept code: 10042435 display: Sudden death NOS definition: An unexpected cessation of life that cannot be attributed to a CTCAE term associated with Grade 5. concept code: 10042458 display: Suicidal ideation definition: A disorder characterized by thoughts of taking one's own life. concept code: 10042464 display: Suicide attempt definition: A disorder characterized by self-inflicted harm in an attempt to end one's own life. concept code: 10042554 display: Superficial thrombophlebitis definition: A disorder characterized by a blood clot and inflammation involving a superficial vein of the extremities. concept code: 10042569 display: Superior vena cava syndrome definition: A disorder characterized by obstruction of the blood flow in the superior vena cava. Signs and symptoms include swelling and cyanosis of the face, neck, and upper arms, cough, orthopnea and headache. concept code: 10042604 display: Supraventricular tachycardia definition: A disorder characterized by a dysrhythmia with a heart rate greater than 100 beats per minute that originates above the ventricles. concept code: 10042613 display: Surgical and medical procedures - Other, specify definition: No Value Exists concept code: 10042772 display: Syncope definition: A disorder characterized by spontaneous loss of consciousness caused by insufficient blood supply to the brain. concept code: 10043189 display: Telangiectasia definition: A disorder characterized by local dilatation of small vessels resulting in red discoloration of the skin or mucous membranes. concept code: 10043306 display: Testicular disorder definition: A disorder characterized by involvement of the testis. concept code: 10043345 display: Testicular pain definition: A disorder characterized by a sensation of marked discomfort in the testis. concept code: 10043565 display: Thromboembolic event definition: A disorder characterized by occlusion of a vessel by a thrombus that has migrated from a distal site via the blood stream. concept code: 10043648 display: Thrombotic thrombocytopenic purpura definition: A disorder characterized by the presence of microangiopathic hemolytic anemia, thrombocytopenic purpura, fever, renal abnormalities and neurological abnormalities such as seizures, hemiplegia, and visual disturbances. It is an acute or subacute condition. concept code: 10043882 display: Tinnitus definition: A disorder characterized by noise in the ears, such as ringing, buzzing, roaring or clicking. concept code: 10044030 display: Tooth development disorder definition: A disorder characterized by a pathological process of the teeth occurring during tooth development. concept code: 10044031 display: Tooth discoloration definition: A disorder characterized by a change in tooth hue or tint. concept code: 10044055 display: Toothache definition: A disorder characterized by a sensation of marked discomfort in the tooth. concept code: 10044223 display: Toxic epidermal necrolysis definition: A disorder characterized by greater than 30% total body skin area separation of dermis. The syndrome is thought to be a hypersensitivity complex affecting the skin and the mucous membranes. concept code: 10044291 display: Tracheal obstruction definition: A finding of blockage of the lumen of the trachea. concept code: 10044302 display: Tracheitis definition: A disorder characterized by an infectious process involving the trachea. concept code: 10044391 display: Transient ischemic attacks definition: A disorder characterized by a brief attack (less than 24 hours) of cerebral dysfunction of vascular origin, with no persistent neurological deficit. concept code: 10044565 display: Tremor definition: A disorder characterized by the uncontrolled shaking movement of the whole body or individual parts. concept code: 10044684 display: Trismus definition: A disorder characterized by lack of ability to open the mouth fully due to a decrease in the range of motion of the muscles of mastication. concept code: 10045152 display: Tumor lysis syndrome definition: A disorder characterized by metabolic abnormalities that result from a spontaneous or therapy-related cytolysis of tumor cells. concept code: 10045158 display: Tumor pain definition: A disorder characterized by marked discomfort from a neoplasm that may be pressing on a nerve, blocking blood vessels, inflamed or fractured from metastasis. concept code: 10045271 display: Typhlitis definition: A disorder characterized by inflammation of the cecum. concept code: 10045542 display: Unintended pregnancy definition: A disorder characterized by an unexpected pregnancy at the time of conception. concept code: 10046300 display: Upper respiratory infection definition: A disorder characterized by an infectious process involving the upper respiratory tract (nose, paranasal sinuses, pharynx, larynx, or trachea). concept code: 10046539 display: Urinary frequency definition: A disorder characterized by urination at short intervals. concept code: 10046543 display: Urinary incontinence definition: A disorder characterized by inability to control the flow of urine from the bladder. concept code: 10046555 display: Urinary retention definition: A disorder characterized by accumulation of urine within the bladder because of the inability to urinate. concept code: 10046571 display: Urinary tract infection definition: A disorder characterized by an infectious process involving the urinary tract, most commonly the bladder and the urethra. concept code: 10046593 display: Urinary urgency definition: A disorder characterized by a sudden compelling urge to urinate. concept code: 10046628 display: Urine discoloration definition: A disorder characterized by a change in the color of the urine. concept code: 10046735 display: Urticaria definition: A disorder characterized by an itchy skin eruption characterized by wheals with pale interiors and well-defined red margins. concept code: 10046789 display: Uterine hemorrhage definition: A disorder characterized by bleeding from the uterus. concept code: 10046809 display: Uterine pain definition: A disorder characterized by a sensation of marked discomfort in the uterus. concept code: 10046810 display: Uterine perforation definition: A disorder characterized by a rupture in the uterine wall. concept code: 10046851 display: Uveitis definition: A disorder characterized by inflammation to the uvea of the eye. concept code: 10046901 display: Vaginal discharge definition: A disorder characterized by vaginal secretions. Mucus produced by the cervical glands is discharged from the vagina naturally, especially during the childbearing years. concept code: 10046904 display: Vaginal dryness definition: A disorder characterized by an uncomfortable feeling of itching and burning in the vagina. concept code: 10046912 display: Vaginal hemorrhage definition: A disorder characterized by bleeding from the vagina. concept code: 10046914 display: Vaginal infection definition: A disorder characterized by an infectious process involving the vagina. concept code: 10046916 display: Vaginal inflammation definition: A disorder characterized by inflammation involving the vagina. Symptoms may include redness, edema, marked discomfort and an increase in vaginal discharge. concept code: 10046937 display: Vaginal pain definition: A disorder characterized by a sensation of marked discomfort in the vagina. concept code: 10046947 display: Vaginismus definition: A disorder characterized by involuntary spasms of the pelvic floor muscles, resulting in pathologic tightness of the vaginal wall during penetration such as during sexual intercourse. concept code: 10047065 display: Vascular disorders - Other, specify definition: No Value Exists concept code: 10047115 display: Vasculitis definition: A disorder characterized by inflammation involving the wall of a vessel. concept code: 10047166 display: Vasovagal reaction definition: A disorder characterized by a sudden drop of the blood pressure, bradycardia, and peripheral vasodilation that may lead to loss of consciousness. It results from an increase in the stimulation of the vagus nerve. concept code: 10047228 display: Venous injury definition: A finding of damage to a vein. concept code: 10047281 display: Ventricular arrhythmia definition: A disorder characterized by a dysrhythmia that originates in the ventricles. concept code: 10047290 display: Ventricular fibrillation definition: A disorder characterized by a dysrhythmia without discernible QRS complexes due to rapid repetitive excitation of myocardial fibers without coordinated contraction of the ventricles. concept code: 10047302 display: Ventricular tachycardia definition: A disorder characterized by a dysrhythmia with a heart rate greater than 100 beats per minute that originates distal to the bundle of His. concept code: 10047340 display: Vertigo definition: A disorder characterized by a sensation as if the external world were revolving around the patient (objective vertigo) or as if he himself were revolving in space (subjective vertigo). concept code: 10047386 display: Vestibular disorder definition: A disorder characterized by dizziness, imbalance, nausea, and vision problems. concept code: 10047488 display: Virilization definition: A disorder characterized by inappropriate masculinization occurring in a female or prepubertal male. concept code: 10047580 display: Vital capacity abnormal definition: A finding based on pulmonary function test results that indicate an abnormal vital capacity (amount of exhaled after a maximum inhalation) when compared to the predicted value. concept code: 10047656 display: Vitreous hemorrhage definition: A disorder characterized by blood extravasation into the vitreous humor. concept code: 10047681 display: Voice alteration definition: A disorder characterized by a change in the sound and/or speed of the voice. concept code: 10047700 display: Vomiting definition: A disorder characterized by the reflexive act of ejecting the contents of the stomach through the mouth. concept code: 10047848 display: Watering eyes definition: A disorder of excessive tearing in the eyes; it can be caused by overproduction of tears or impaired drainage of the tear duct. concept code: 10047896 display: Weight gain definition: A finding characterized by an increase in overall body weight; for pediatrics, greater than the baseline growth curve. concept code: 10047900 display: Weight loss definition: A finding characterized by a decrease in overall body weight; for pediatrics, less than the baseline growth curve. concept code: 10047924 display: Wheezing definition: A disorder characterized by a high-pitched, whistling sound during breathing. It results from the narrowing or obstruction of the respiratory airways. concept code: 10048015 display: Wolff-Parkinson-White syndrome definition: A disorder characterized by the presence of an accessory conductive pathway between the atria and the ventricles that causes premature ventricular activation. concept code: 10048031 display: Wound dehiscence definition: A finding of separation of the approximated margins of a surgical wound. concept code: 10048038 display: Wound infection definition: A disorder characterized by an infectious process involving the wound. concept code: 10048049 display: Wrist fracture definition: A finding of traumatic injury to the wrist joint in which the continuity of a wrist bone is broken. concept code: 10048293 display: Leukemia secondary to oncology chemotherapy definition: A disorder characterized by leukemia arising as a result of the mutagenic effect of chemotherapy agents. concept code: 10048492 display: Corneal ulcer definition: A disorder characterized by an area of epithelial tissue loss on the surface of the cornea. It is associated with inflammatory cells in the cornea and anterior chamber. concept code: 10048580 display: Bone marrow hypocellular definition: A disorder characterized by the inability of the bone marrow to produce hematopoietic elements. concept code: 10048642 display: Lymphocele definition: A disorder characterized by a cystic lesion containing lymph. concept code: 10048677 display: Buttock pain definition: A disorder characterized by marked discomfort sensation in the buttocks. concept code: 10048706 display: Joint range of motion decreased definition: A disorder characterized by a decrease in joint flexibility of any joint. concept code: 10048762 display: Tooth infection definition: A disorder characterized by an infectious process involving a tooth. concept code: 10048994 display: Bladder spasm definition: A disorder characterized by a sudden and involuntary contraction of the bladder wall. concept code: 10049120 display: Scalp pain definition: A disorder characterized by marked discomfort sensation in the skin covering the top and the back of the head. concept code: 10049182 display: White blood cell decreased definition: A finding based on laboratory test results that indicate an decrease in number of white blood cells in a blood specimen. concept code: 10049192 display: Pancreatic fistula definition: A disorder characterized by an abnormal communication between the pancreas and another organ or anatomic site. concept code: 10049281 display: Nail loss definition: A disorder characterized by loss of all or a portion of the nail. concept code: 10049468 display: Intestinal stoma site bleeding definition: A finding of blood leakage from the intestinal stoma. concept code: 10049737 display: Treatment related secondary malignancy definition: A disorder characterized by development of a malignancy most probably as a result of treatment for a previously existing malignancy. concept code: 10050028 display: Pharyngeal stenosis definition: A disorder characterized by a narrowing of the pharyngeal airway. concept code: 10050068 display: Edema limbs definition: A disorder characterized by swelling due to excessive fluid accumulation in the upper or lower extremities. concept code: 10050094 display: Duodenal stenosis definition: A disorder characterized by a narrowing of the lumen of the duodenum. concept code: 10050457 display: Pancreatic anastomotic leak definition: A finding of leakage due to breakdown of a pancreatic anastomosis (surgical connection of two separate anatomic structures). concept code: 10050458 display: Biliary anastomotic leak definition: A finding of leakage of bile due to breakdown of a biliary anastomosis (surgical connection of two separate anatomic structures). concept code: 10050528 display: Ejection fraction decreased definition: The percentage computed when the amount of blood ejected during a ventricular contraction of the heart is compared to the amount that was present prior to the contraction. concept code: 10050662 display: Prostate infection definition: A disorder characterized by an infectious process involving the prostate gland. concept code: 10050816 display: Tracheal stenosis definition: A disorder characterized by a narrowing of the trachea. concept code: 10050823 display: Lymph gland infection definition: A disorder characterized by an infectious process involving the lymph nodes. concept code: 10051228 display: Chylothorax definition: A disorder characterized by milky pleural effusion (abnormal collection of fluid) resulting from accumulation of lymph fluid in the pleural cavity. concept code: 10051272 display: Facial muscle weakness definition: A disorder characterized by a reduction in the strength of the facial muscles. concept code: 10051341 display: Bile duct stenosis definition: A disorder characterized by a narrowing of the lumen of the bile duct. concept code: 10051472 display: Periorbital infection definition: A disorder characterized by an infectious process involving the orbit of the eye. concept code: 10051592 display: Acute coronary syndrome definition: A disorder characterized by signs and symptoms related to acute ischemia of the myocardium secondary to coronary artery disease. The clinical presentation covers a spectrum of heart diseases from unstable angina to myocardial infarction. concept code: 10051741 display: Pancreas infection definition: A disorder characterized by an infectious process involving the pancreas. concept code: 10051746 display: Lower gastrointestinal hemorrhage definition: A disorder characterized by bleeding from the lower gastrointestinal tract (small intestine, large intestine, and anus). concept code: 10051792 display: Infusion related reaction definition: A disorder characterized by adverse reaction to the infusion of pharmacological or biological substances. concept code: 10051837 display: Skin induration definition: A disorder characterized by an area of hardness in the skin. concept code: 10051886 display: Gastric necrosis definition: A disorder characterized by a necrotic process occurring in the gastric wall. concept code: 10052015 display: Cytokine release syndrome definition: A disorder characterized by nausea, headache, tachycardia, hypotension, rash, and shortness of breath; it is caused by the release of cytokines from the cells. concept code: 10052298 display: Urethral infection definition: A disorder characterized by an infectious process involving the urethra. concept code: 10052426 display: Glucose intolerance definition: A disorder characterized by an inability to properly metabolize glucose. concept code: 10053481 display: Bronchopleural fistula definition: A disorder characterized by an abnormal communication between a bronchus and the pleural cavity. concept code: 10053496 display: Vaginal stricture definition: A disorder characterized by a narrowing of the vaginal canal. concept code: 10053565 display: Pericardial tamponade definition: A disorder characterized by an increase in intrapericardial pressure due to the collection of blood or fluid in the pericardium. concept code: 10053661 display: Oculomotor nerve disorder definition: A disorder characterized by involvement of the oculomotor nerve (third cranial nerve). concept code: 10053662 display: Abducens nerve disorder definition: A disorder characterized by involvement of the abducens nerve (sixth cranial nerve). concept code: 10053692 display: Wound complication definition: A finding of development of a new problem at the site of an existing wound. concept code: 10054382 display: Feminization acquired definition: A disorder characterized by the development of secondary female sex characteristics in males due to extrinsic factors. concept code: 10054482 display: Neck edema definition: A disorder characterized by swelling due to an accumulation of excessive fluid in the neck. concept code: 10054520 display: Oral dysesthesia definition: A disorder characterized by a burning or tingling sensation on the lips, tongue or entire mouth. concept code: 10054524 display: Palmar-plantar erythrodysesthesia syndrome definition: A disorder characterized by redness, marked discomfort, swelling, and tingling in the palms of the hands or the soles of the feet. concept code: 10054541 display: Periorbital edema definition: A disorder characterized by swelling due to an excessive accumulation of fluid around the orbits of the face. concept code: 10054692 display: Visceral arterial ischemia definition: A disorder characterized by a decrease in blood supply due to narrowing or blockage of a visceral (mesenteric) artery. concept code: 10054746 display: Fetal growth retardation definition: A disorder characterized by inhibition of fetal growth resulting in the inability of the fetus to achieve its potential weight. concept code: 10055005 display: Ovarian infection definition: A disorder characterized by an infectious process involving the ovary. concept code: 10055026 display: Prostatic obstruction definition: A disorder characterized by compression of the urethra secondary to enlargement of the prostate gland. This results in voiding difficulties (straining to void, slow urine stream, and incomplete emptying of the bladder). concept code: 10055078 display: Bronchial infection definition: A disorder characterized by an infectious process involving the bronchi. concept code: 10055226 display: Anal hemorrhage definition: A disorder characterized by bleeding from the anal region. concept code: 10055242 display: Duodenal hemorrhage definition: A disorder characterized by bleeding from the duodenum. concept code: 10055287 display: Ileal hemorrhage definition: A disorder characterized by bleeding from the ileal wall. concept code: 10055291 display: Intra-abdominal hemorrhage definition: A disorder characterized by bleeding in the abdominal cavity. concept code: 10055298 display: Intraoperative hemorrhage definition: A finding of uncontrolled bleeding during a surgical procedure. concept code: 10055300 display: Jejunal hemorrhage definition: A disorder characterized by bleeding from the jejunal wall. concept code: 10055315 display: Pharyngeal hemorrhage definition: A disorder characterized by bleeding from the pharynx. concept code: 10055319 display: Pleural hemorrhage definition: A disorder characterized by bleeding from the pleural cavity. concept code: 10055322 display: Postoperative hemorrhage definition: A finding of bleeding occurring after a surgical procedure. concept code: 10055325 display: Prostatic hemorrhage definition: A disorder characterized by bleeding from the prostate gland. concept code: 10055347 display: Testicular hemorrhage definition: A disorder characterized by bleeding from the testis. concept code: 10055356 display: Upper gastrointestinal hemorrhage definition: A disorder characterized by bleeding from the upper gastrointestinal tract (oral cavity, pharynx, esophagus, and stomach). concept code: 10055472 display: Esophageal perforation definition: A disorder characterized by a rupture in the wall of the esophagus. concept code: 10055599 display: Hemoglobin increased definition: A finding based on laboratory test results that indicate increased levels of hemoglobin in a biological specimen. concept code: 10056238 display: Phantom pain definition: A disorder characterized by marked discomfort related to a limb or an organ that is removed from or is not physically part of the body. concept code: 10056356 display: Mediastinal hemorrhage definition: A disorder characterized by bleeding from the mediastinum. concept code: 10056388 display: Olfactory nerve disorder definition: A disorder characterized by involvement of the olfactory nerve (first cranial nerve). concept code: 10056519 display: Abdominal infection definition: A disorder characterized by an infectious process involving the abdominal cavity. concept code: 10056522 display: Hepatic infection definition: A disorder characterized by an infectious process involving the liver. concept code: 10056627 display: Phlebitis infective definition: A disorder characterized by an infectious process involving the vein. Clinical manifestations include erythema, marked discomfort, swelling, and induration along the course of the infected vein. concept code: 10056681 display: Salivary duct inflammation definition: A disorder characterized by inflammation of the salivary duct. concept code: 10056745 display: Postoperative thoracic procedure complication definition: A finding of a previously undocumented problem that occurs after a thoracic procedure. concept code: 10056910 display: GGT increased definition: A finding based on laboratory test results that indicate higher than normal levels of the enzyme gamma-glutamyltransferase in the blood specimen. GGT (gamma-glutamyltransferase ) catalyzes the transfer of a gamma glutamyl group from a gamma glutamyl peptide to another peptide, amino acids or water. concept code: 10057066 display: Delayed orgasm definition: A disorder characterized by sexual dysfunction characterized by a delay in climax. concept code: 10057262 display: Peritoneal infection definition: A disorder characterized by an infectious process involving the peritoneum. concept code: 10057483 display: Mediastinal infection definition: A disorder characterized by an infectious process involving the mediastinum. concept code: 10058084 display: Precocious puberty definition: A disorder characterized by unusually early development of secondary sexual features; the onset of sexual maturation begins usually before age 8 for girls and before age 9 for boys. concept code: 10058096 display: Pancreatic necrosis definition: A disorder characterized by a necrotic process occurring in the pancreas. concept code: 10058597 display: Right ventricular dysfunction definition: A disorder characterized by impairment of right ventricular function associated with low ejection fraction and a decrease in motility of the right ventricular wall. concept code: 10058674 display: Pelvic infection definition: A disorder characterized by an infectious process involving the pelvic cavity. concept code: 10058720 display: Edema trunk definition: A disorder characterized by swelling due to excessive fluid accumulation in the trunk area. concept code: 10058804 display: Esophageal infection definition: A disorder characterized by an infectious process involving the esophagus. concept code: 10058838 display: Enterocolitis infectious definition: A disorder characterized by an infectious process involving the small and large intestines. concept code: 10059094 display: Intestinal stoma obstruction definition: A finding of blockage of the normal flow of the contents of the intestinal stoma. concept code: 10059095 display: Intestinal stoma leak definition: A finding of leakage of contents from an intestinal stoma (surgically created opening on the surface of the body). concept code: 10059446 display: Gallbladder necrosis definition: A disorder characterized by a necrotic process occurring in the gallbladder. concept code: 10059639 display: Laryngeal obstruction definition: A disorder characterized by blockage of the laryngeal airway. concept code: 10059827 display: Rhinitis infective definition: A disorder characterized by an infectious process involving the nasal mucosal. concept code: 10059895 display: Urine output decreased definition: A finding based on test results that indicate urine production is less relative to previous output. concept code: 10060602 display: Hematosalpinx definition: A disorder characterized by the presence of blood in a fallopian tube. concept code: 10060640 display: Hemorrhoidal hemorrhage definition: A disorder characterized by bleeding from the hemorrhoids. concept code: 10060890 display: Trigeminal nerve disorder definition: A disorder characterized by involvement of the trigeminal nerve (fifth cranial nerve). concept code: 10060929 display: Accessory nerve disorder definition: A disorder characterized by involvement of the accessory nerve (eleventh cranial nerve). concept code: 10061017 display: Bone infection definition: A disorder characterized by an infectious process involving the bones. concept code: 10061103 display: Dermatitis radiation definition: A finding of cutaneous inflammatory reaction occurring as a result of exposure to biologically effective levels of ionizing radiation. concept code: 10061145 display: Eyelid function disorder definition: A disorder characterized by impaired eyelid function. concept code: 10061149 display: Female genital tract fistula definition: A disorder characterized by an abnormal communication between a female reproductive system organ and another organ or anatomic site. concept code: 10061185 display: Glossopharyngeal nerve disorder definition: A disorder characterized by involvement of the glossopharyngeal nerve (ninth cranial nerve). concept code: 10061212 display: Hypoglossal nerve disorder definition: A disorder characterized by involvement of the hypoglossal nerve (twelfth cranial nerve). concept code: 10061229 display: Lung infection definition: A disorder characterized by an infectious process involving the lungs. concept code: 10061261 display: Lactation disorder definition: A disorder characterized by disturbances of milk secretion. It is not necessarily related to pregnancy that is observed in females and can be observed in males. concept code: 10061304 display: Nail infection definition: A disorder characterized by an infectious process involving the nail. concept code: 10061322 display: Optic nerve disorder definition: A disorder characterized by involvement of the optic nerve (second cranial nerve). concept code: 10061339 display: Perineal pain definition: A disorder characterized by a sensation of marked discomfort in the area between the genital organs and the anus. concept code: 10061351 display: Pleural infection definition: A disorder characterized by an infectious process involving the pleura. concept code: 10061389 display: Tricuspid valve disease definition: A disorder characterized by a defect in tricuspid valve function or structure. concept code: 10061403 display: Vagus nerve disorder definition: A disorder characterized by involvement of the vagus nerve (tenth cranial nerve). concept code: 10061457 display: Facial nerve disorder definition: A disorder characterized by involvement of the facial nerve (seventh cranial nerve). concept code: 10061461 display: Erectile dysfunction definition: A disorder characterized by the persistent or recurrent inability to achieve or to maintain an erection during sexual activity. concept code: 10061510 display: Scleral disorder definition: A disorder characterized by involvement of the sclera of the eye. concept code: 10061532 display: Mitral valve disease definition: A disorder characterized by a defect in mitral valve function or structure. concept code: 10061541 display: Pulmonary valve disease definition: A disorder characterized by a defect in pulmonary valve function or structure. concept code: 10061574 display: Urinary tract obstruction definition: A disorder characterized by blockage of the normal flow of contents of the urinary tract. concept code: 10061589 display: Aortic valve disease definition: A disorder characterized by a defect in aortic valve function or structure. concept code: 10061640 display: Anorectal infection definition: A disorder characterized by an infectious process involving the anal area and the rectum. concept code: 10061664 display: Autoimmune disorder definition: A disorder resulting from loss of function or tissue destruction of an organ or multiple organs, arising from humoral or cellular immune responses of the individual to his own tissue constituents. concept code: 10061695 display: Biliary tract infection definition: A disorder characterized by an infectious process involving the biliary tract. concept code: 10061788 display: Corneal infection definition: A disorder characterized by an infectious process involving the cornea. concept code: 10061912 display: Penile infection definition: A disorder characterized by an infectious process involving the penis. concept code: 10061928 display: Radiculitis definition: A disorder characterized by inflammation involving a nerve root. Patients experience marked discomfort radiating along a nerve path because of spinal pressure on the connecting nerve root. concept code: 10061970 display: Gastric stenosis definition: A disorder characterized by a narrowing of the lumen of the stomach. concept code: 10062112 display: Splenic infection definition: A disorder characterized by an infectious process involving the spleen. concept code: 10062156 display: Scrotal infection definition: A disorder characterized by an infectious process involving the scrotum. concept code: 10062169 display: Vascular access complication definition: A finding of a previously undocumented problem related to the vascular access site. concept code: 10062225 display: Urinary tract pain definition: A disorder characterized by a sensation of marked discomfort in the urinary tract. concept code: 10062233 display: Uterine infection definition: A disorder characterized by an infectious process involving the endometrium. It may extend to the myometrium and parametrial tissues. concept code: 10062244 display: Sinus disorder definition: A disorder characterized by involvement of the paranasal sinuses. concept code: 10062255 display: Soft tissue infection definition: A disorder characterized by an infectious process involving soft tissues. concept code: 10062263 display: Small intestinal stenosis definition: A disorder characterized by a narrowing of the lumen of the small intestine. concept code: 10062283 display: Nail ridging definition: A disorder characterized by vertical or horizontal ridges on the nails. concept code: 10062315 display: Lipohypertrophy definition: A disorder characterized by hypertrophy of the subcutaneous adipose tissue at the site of multiple subcutaneous injections of insulin. concept code: 10062466 display: Localized edema definition: A disorder characterized by swelling due to excessive fluid accumulation at a specific anatomic site. concept code: 10062501 display: Non-cardiac chest pain definition: A disorder characterized by discomfort in the chest unrelated to a heart disorder. concept code: 10062548 display: Tracheal hemorrhage definition: A finding of bleeding from the trachea. concept code: 10062570 display: Enterovesical fistula definition: A disorder characterized by an abnormal communication between the urinary bladder and the intestine. concept code: 10062572 display: Generalized muscle weakness definition: A disorder characterized by a reduction in the strength of muscles in multiple anatomic sites. concept code: 10062632 display: Gallbladder infection definition: A disorder characterized by an infectious process involving the gallbladder. concept code: 10062646 display: Pancreatic enzymes decreased definition: A finding based on laboratory test results that indicate an decrease in levels of pancreatic enzymes in a biological specimen. concept code: 10062667 display: Laryngopharyngeal dysesthesia definition: A disorder characterized by an uncomfortable persistent sensation in the area of the laryngopharynx. concept code: 10062872 display: Dysesthesia definition: A disorder characterized by distortion of sensory perception, resulting in an abnormal and unpleasant sensation. concept code: 10063057 display: Cystitis noninfective definition: A disorder characterized by inflammation of the bladder which is not caused by an infection of the urinary tract. concept code: 10063190 display: Rectal mucositis definition: A disorder characterized by inflammation of the mucous membrane of the rectum. concept code: 10063524 display: Bronchial stricture definition: A disorder characterized by a narrowing of the bronchial tube. concept code: 10063575 display: Bladder perforation definition: A disorder characterized by a rupture in the bladder wall. concept code: 10063636 display: Pyramidal tract syndrome definition: A disorder characterized by dysfunction of the corticospinal (pyramidal) tracts of the spinal cord. Symptoms include an increase in the muscle tone in the lower extremities, hyperreflexia, positive Babinski and a decrease in fine motor coordination. concept code: 10063761 display: Reversible posterior leukoencephalopathy syndrome definition: A disorder characterized by headaches, mental status changes, visual disturbances, and seizures associated with imaging findings of posterior leukoencephalopathy. It has been observed in association with hypertensive encephalopathy, eclampsia, and immunosuppressive and cytotoxic drug treatment. It is an acute or subacute reversible condition. concept code: 10064026 display: Pelvic floor muscle weakness definition: A disorder characterized by a reduction in the strength of the muscles of the pelvic floor. concept code: 10064505 display: Stoma site infection definition: A disorder characterized by an infectious process involving a stoma (surgically created opening on the surface of the body). concept code: 10064658 display: Osteonecrosis of jaw definition: A disorder characterized by a necrotic process occurring in the bone of the mandible. concept code: 10064687 display: Device related infection definition: A disorder characterized by an infectious process involving the use of a medical device. concept code: 10064774 display: Infusion site extravasation definition: A disorder characterized by leakage of a pharmacologic or a biologic substance from the infusion site into the surrounding tissue. Signs and symptoms include induration, erythema, swelling, burning sensation and marked discomfort at the infusion site. concept code: 10064848 display: Chronic kidney disease definition: A disorder characterized by gradual and usually permanent loss of kidney function resulting in renal failure. concept code: 10065368 display: Urinary fistula definition: A disorder characterized by an abnormal communication between any part of the urinary system and another organ or anatomic site. concept code: 10065417 display: Brachial plexopathy definition: A disorder characterized by regional paresthesia of the brachial plexus, marked discomfort and muscle weakness, and limited movement in the arm or hand. concept code: 10065703 display: Pancreatic duct stenosis definition: A disorder characterized by a narrowing of the lumen of the pancreatic duct. concept code: 10065704 display: Peritoneal necrosis definition: A disorder characterized by a necrotic process occurring in the peritoneum. concept code: 10065705 display: Pharyngeal anastomotic leak definition: A finding of leakage due to breakdown of a pharyngeal anastomosis (surgical connection of two separate anatomic structures). concept code: 10065706 display: Pharyngeal necrosis definition: A disorder characterized by a necrotic process occurring in the pharynx. concept code: 10065707 display: Rectal obstruction definition: A disorder characterized by blockage of the normal flow of the intestinal contents in the rectum. concept code: 10065709 display: Rectal necrosis definition: A disorder characterized by a necrotic process occurring in the rectal wall. concept code: 10065710 display: Small intestinal mucositis definition: A disorder characterized by inflammation of the mucous membrane of the small intestine. concept code: 10065712 display: Gastrointestinal stoma necrosis definition: A finding of a necrotic process occurring in the gastrointestinal tract stoma. concept code: 10065713 display: Gastric fistula definition: A disorder characterized by an abnormal communication between the stomach and another organ or anatomic site. concept code: 10065719 display: Jejunal fistula definition: A disorder characterized by an abnormal communication between the jejunum and another organ or anatomic site. concept code: 10065720 display: Oral cavity fistula definition: A disorder characterized by an abnormal communication between the oral cavity and another organ or anatomic site. concept code: 10065721 display: Anal mucositis definition: A disorder characterized by inflammation of the mucous membrane of the anus. concept code: 10065722 display: Anal necrosis definition: A disorder characterized by a necrotic process occurring in the anal region. concept code: 10065727 display: Esophageal necrosis definition: A disorder characterized by a necrotic process occurring in the esophageal wall. concept code: 10065728 display: Ileal fistula definition: A disorder characterized by an abnormal communication between the ileum and another organ or anatomic site. concept code: 10065730 display: Ileal obstruction definition: A disorder characterized by blockage of the normal flow of the intestinal contents in the ileum. concept code: 10065732 display: Jejunal obstruction definition: A disorder characterized by blockage of the normal flow of the intestinal contents in the jejunum. concept code: 10065735 display: Laryngeal inflammation definition: A disorder characterized by an inflammation involving the larynx. concept code: 10065738 display: Unequal limb length definition: A disorder characterized by of a discrepancy between the lengths of the lower or upper extremities. concept code: 10065744 display: Arteritis infective definition: A disorder characterized by an infectious process involving an artery. concept code: 10065745 display: Prolapse of intestinal stoma definition: A finding of protrusion of the intestinal stoma (surgically created opening on the surface of the body) above the abdominal surface. concept code: 10065746 display: Bronchopulmonary hemorrhage definition: A disorder characterized by bleeding from the bronchial wall and/or lung parenchyma. concept code: 10065747 display: Cecal hemorrhage definition: A disorder characterized by bleeding from the cecum. concept code: 10065748 display: Urostomy site bleeding definition: A finding of bleeding from the urostomy site. concept code: 10065749 display: Tracheostomy site bleeding definition: A finding of blood leakage from the tracheostomy site. concept code: 10065752 display: Duodenal infection definition: A disorder characterized by an infectious process involving the duodenum. concept code: 10065755 display: Lip infection definition: A disorder characterized by an infectious process involving the lips. concept code: 10065759 display: Laryngeal hemorrhage definition: A disorder characterized by bleeding from the larynx. concept code: 10065761 display: Cecal infection definition: A disorder characterized by an infectious process involving the cecum. concept code: 10065762 display: Spermatic cord hemorrhage definition: A disorder characterized by bleeding from the spermatic cord. concept code: 10065763 display: Ovarian hemorrhage definition: A disorder characterized by bleeding from the ovary. concept code: 10065764 display: Mucosal infection definition: A disorder characterized by an infectious process involving a mucosal surface. concept code: 10065765 display: Cranial nerve infection definition: A disorder characterized by an infectious process involving a cranial nerve. concept code: 10065766 display: Peripheral nerve infection definition: A disorder characterized by an infectious process involving the peripheral nerves. concept code: 10065771 display: Small intestine infection definition: A disorder characterized by an infectious process involving the small intestine. concept code: 10065772 display: Vulval infection definition: A disorder characterized by an infectious process involving the vulva. concept code: 10065773 display: Lymph leakage definition: A disorder characterized by the loss of lymph fluid into the surrounding tissue or body cavity. concept code: 10065775 display: Abdominal soft tissue necrosis definition: A disorder characterized by a necrotic process occurring in the soft tissues of the abdominal wall. concept code: 10065776 display: Muscle weakness lower limb definition: A disorder characterized by a reduction in the strength of the lower limb muscles. concept code: 10065777 display: Soft tissue necrosis lower limb definition: A disorder characterized by a necrotic process occurring in the soft tissues of the lower extremity. concept code: 10065778 display: Soft tissue necrosis upper limb definition: A disorder characterized by a necrotic process occurring in the soft tissues of the upper extremity. concept code: 10065779 display: Head soft tissue necrosis definition: A disorder characterized by a necrotic process occurring in the soft tissues of the head. concept code: 10065780 display: Muscle weakness left-sided definition: A disorder characterized by a reduction in the strength of the muscles on the left side of the body. concept code: 10065781 display: Neck soft tissue necrosis definition: A disorder characterized by a necrotic process occurring in the soft tissues of the neck. concept code: 10065783 display: Musculoskeletal deformity definition: A disorder characterized by of a malformation of the musculoskeletal system. concept code: 10065784 display: Central nervous system necrosis definition: A disorder characterized by a necrotic process occurring in the brain and/or spinal cord. concept code: 10065785 display: External ear pain definition: A disorder characterized by a sensation of marked discomfort in the external ear region. concept code: 10065786 display: Laryngeal fistula definition: A disorder characterized by an abnormal communication between the larynx and another organ or anatomic site. concept code: 10065787 display: Tracheal fistula definition: A disorder characterized by an abnormal communication between the trachea and another organ or anatomic site. concept code: 10065788 display: Fallopian tube anastomotic leak definition: A finding of leakage due to breakdown of a fallopian tube anastomosis (surgical connection of two separate anatomic structures). concept code: 10065789 display: Fallopian tube obstruction definition: A disorder characterized by blockage of the normal flow of the contents in the fallopian tube. concept code: 10065790 display: Fallopian tube perforation definition: A finding of rupture of the fallopian tube wall. concept code: 10065791 display: Fallopian tube stenosis definition: A disorder characterized by a narrowing of the fallopian tube lumen. concept code: 10065793 display: Pelvic soft tissue necrosis definition: A disorder characterized by a necrotic process occurring in the soft tissues of the pelvis. concept code: 10065794 display: Muscle weakness right-sided definition: A disorder characterized by a reduction in the strength of the muscles on the right side of the body. concept code: 10065795 display: Muscle weakness trunk definition: A disorder characterized by a reduction in the strength of the trunk muscles. concept code: 10065796 display: Joint range of motion decreased cervical spine definition: A disorder characterized by a decrease in flexibility of a cervical spine joint. concept code: 10065798 display: Superficial soft tissue fibrosis definition: A disorder characterized by fibrotic degeneration of the superficial soft tissues. concept code: 10065799 display: Fibrosis deep connective tissue definition: A disorder characterized by fibrotic degeneration of the deep connective tissues. concept code: 10065800 display: Joint range of motion decreased lumbar spine definition: A disorder characterized by a decrease in flexibility of a lumbar spine joint. concept code: 10065802 display: Bladder anastomotic leak definition: A finding of leakage of urine due to breakdown of a bladder anastomosis (surgical connection of two separate anatomic structures). concept code: 10065803 display: Kidney anastomotic leak definition: A finding of leakage of urine due to breakdown of a kidney anastomosis (surgical connection of two separate anatomic structures). concept code: 10065805 display: Spermatic cord obstruction definition: A disorder characterized by blockage of the normal flow of the contents of the spermatic cord. concept code: 10065811 display: Uterine fistula definition: A disorder characterized by an abnormal communication between the uterus and another organ or anatomic site. concept code: 10065813 display: Vaginal fistula definition: A disorder characterized by an abnormal communication between the vagina and another organ or anatomic site. concept code: 10065814 display: Ureteric anastomotic leak definition: A finding of leakage due to breakdown of a ureteral anastomosis (surgical connection of two separate anatomic structures). concept code: 10065815 display: Urethral anastomotic leak definition: A finding of leakage due to breakdown of a urethral anastomosis (surgical connection of two separate anatomic structures). concept code: 10065817 display: Vaginal obstruction definition: A disorder characterized by blockage of vaginal canal. concept code: 10065818 display: Vaginal perforation definition: A disorder characterized by a rupture in the vaginal wall. concept code: 10065822 display: Prolapse of urostomy definition: A finding of displacement of the urostomy. concept code: 10065823 display: Nipple deformity definition: A disorder characterized by a malformation of the nipple. concept code: 10065825 display: Intraoperative gastrointestinal injury definition: A finding of damage to the gastrointestinal system during a surgical procedure. concept code: 10065826 display: Intraoperative arterial injury definition: A finding of damage to an artery during a surgical procedure. concept code: 10065827 display: Intraoperative hepatobiliary injury definition: A finding of damage to the hepatic parenchyma and/or biliary tract during a surgical procedure. concept code: 10065828 display: Intraoperative urinary injury definition: A finding of damage to the urinary system during a surgical procedure. concept code: 10065829 display: Intraoperative musculoskeletal injury definition: A finding of damage to the musculoskeletal system during a surgical procedure. concept code: 10065830 display: Intraoperative neurological injury definition: A finding of damage to the nervous system during a surgical procedure. concept code: 10065831 display: Intraoperative breast injury definition: A finding of damage to the breast parenchyma during a surgical procedure. concept code: 10065832 display: Intraoperative respiratory injury definition: A finding of damage to the respiratory system during a surgical procedure. concept code: 10065834 display: Intraoperative endocrine injury definition: A finding of damage to the endocrine gland during a surgical procedure. concept code: 10065836 display: IVth nerve disorder definition: A disorder characterized by involvement of the trochlear nerve (fourth cranial nerve). concept code: 10065837 display: External ear inflammation definition: A disorder characterized by inflammation, swelling and redness to the outer ear and ear canal. concept code: 10065838 display: Middle ear inflammation definition: A disorder characterized by inflammation (physiologic response to irritation), swelling and redness to the middle ear. concept code: 10065840 display: Intraoperative reproductive tract injury definition: A finding of damage to the reproductive organs during a surgical procedure. concept code: 10065841 display: Intraoperative ocular injury definition: A finding of damage to the eye during a surgical procedure. concept code: 10065842 display: Intraoperative head and neck injury definition: A finding of damage to the head and neck during a surgical procedure. concept code: 10065843 display: Intraoperative cardiac injury definition: A finding of damage to the heart during a surgical procedure. concept code: 10065844 display: Intraoperative ear injury definition: A finding of damage to the ear during a surgical procedure. concept code: 10065845 display: Intraoperative renal injury definition: A finding of damage to the kidney during a surgical procedure. concept code: 10065846 display: Intraoperative skin injury definition: A finding of damage to the skin during a surgical procedure. concept code: 10065847 display: Intraoperative splenic injury definition: A finding of damage to the spleen during a surgical procedure. concept code: 10065848 display: Intraoperative venous injury definition: A finding of damage to a vein during a surgical procedure. concept code: 10065849 display: Injury to jugular vein definition: A finding of damage to the jugular vein. concept code: 10065851 display: Esophageal fistula definition: A disorder characterized by an abnormal communication between the esophagus and another organ or anatomic site. concept code: 10065873 display: Pulmonary fistula definition: A disorder characterized by an abnormal communication between the lung and another organ or anatomic site. concept code: 10065879 display: Gastrointestinal anastomotic leak definition: A finding of leakage due to breakdown of a gastrointestinal anastomosis (surgical connection of two separate anatomic structures). concept code: 10065880 display: Laryngeal mucositis definition: A disorder characterized by an inflammation involving the mucous membrane of the larynx. concept code: 10065881 display: Pharyngeal mucositis definition: A disorder characterized by an inflammation involving the mucous membrane of the pharynx. concept code: 10065882 display: Urostomy leak definition: A finding of leakage of contents from a urostomy. concept code: 10065883 display: Urostomy obstruction definition: A finding of blockage of the urostomy. concept code: 10065885 display: Urostomy stenosis definition: A finding of narrowing of the opening of a urostomy. concept code: 10065886 display: Uterine anastomotic leak definition: A finding of leakage due to breakdown of a uterine anastomosis (surgical connection of two separate anatomic structures). concept code: 10065887 display: Vaginal anastomotic leak definition: A finding of leakage due to breakdown of a vaginal anastomosis (surgical connection of two separate anatomic structures). concept code: 10065888 display: Vas deferens anastomotic leak definition: A finding of leakage due to breakdown of a vas deferens anastomosis (surgical connection of two separate anatomic structures). concept code: 10065891 display: Large intestinal anastomotic leak definition: A finding of leakage due to breakdown of an anastomosis (surgical connection of two separate anatomic structures) in the large intestine. concept code: 10065892 display: Small intestinal anastomotic leak definition: A finding of leakage due to breakdown of an anastomosis (surgical connection of two separate anatomic structures) in the small bowel. concept code: 10065893 display: Gastric anastomotic leak definition: A finding of leakage due to breakdown of a gastric anastomosis (surgical connection of two separate anatomic structures). concept code: 10065894 display: Rectal anastomotic leak definition: A finding of leakage due to breakdown of a rectal anastomosis (surgical connection of two separate anatomic structures). concept code: 10065895 display: Muscle weakness upper limb definition: A disorder characterized by a reduction in the strength of the upper limb muscles. concept code: 10065897 display: Spermatic cord anastomotic leak definition: A finding of leakage due to breakdown of a spermatic cord anastomosis (surgical connection of two separate anatomic structures). concept code: 10065898 display: Stenosis of gastrointestinal stoma definition: A finding of narrowing of the gastrointestinal stoma (surgically created opening on the surface of the body). concept code: 10065900 display: Tracheal mucositis definition: A disorder characterized by an inflammation involving the mucous membrane of the trachea. concept code: 10065906 display: Carbon monoxide diffusing capacity decreased definition: A finding based on lung function test results that indicate a decrease in the lung capacity to absorb carbon monoxide. concept code: 10065928 display: Uterine obstruction definition: A disorder characterized by blockage of the uterine outlet. concept code: 10065961 display: Esophageal anastomotic leak definition: A finding of leakage due to breakdown of an esophageal anastomosis (surgical connection of two separate anatomic structures). concept code: 10065973 display: Iron overload definition: A disorder characterized by accumulation of iron in the tissues. concept code: 10066480 display: Avascular necrosis definition: A disorder characterized by necrotic changes in the bone tissue due to interruption of blood supply. Most often affecting the epiphysis of the long bones, the necrotic changes result in the collapse and the destruction of the bone structure. concept code: 10066874 display: Gastroesophageal reflux disease definition: A disorder characterized by reflux of the gastric and/or duodenal contents into the distal esophagus. It is chronic in nature and usually caused by incompetence of the lower esophageal sphincter, and may result in injury to the esophageal mucosal. Symptoms include heartburn and acid indigestion. concept code: 10069138 display: Papulopustular rash definition: A disorder characterized by an eruption consisting of papules (a small, raised pimple) and pustules (a small pus filled blister), typically appearing in face, scalp, and upper chest and back Unlike acne, this rash does not present with whiteheads or blackheads, and can be symptomatic, with itchy or tender lesions. concept code: 10069339 display: Acute kidney injury definition: A disorder characterized by the acute loss of renal function and is traditionally classified as pre-renal (low blood flow into kidney), renal (kidney damage) and post-renal causes (ureteral or bladder outflow obstruction). concept code: 10069501 display: Left ventricular systolic dysfunction definition: A disorder characterized by failure of the left ventricle to produce adequate output despite an increase in distending pressure and in end-diastolic volume. Clinical manifestations mayinclude dyspnea, orthopnea, and other signs and symptoms of pulmonary congestion and edema. 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A disorder characterized by swelling of the abdomen.
A disorder characterized by an infectious process involving the abdominal cavity.
A disorder characterized by a sensation of marked discomfort in the abdominal region.
A disorder characterized by a necrotic process occurring in the soft tissues of the abdominal wall.
A disorder characterized by involvement of the abducens nerve (sixth cranial nerve).
A disorder characterized by involvement of the accessory nerve (eleventh cranial nerve).
A disorder characterized by abnormally high acidity (high hydrogen-ion concentration) of the blood and other body tissues.
A disorder characterized by involvement of the acoustic nerve (eighth cranial nerve).
Activated partial thromboplastin time prolonged
An abnormal laboratory test result in which the partial thromboplastin time is found to be greater than the control value. As a possible indicator of coagulopathy, a prolonged partial thromboplastin time (PTT) may occur in a variety of diseases and disorders, both primary and related to treatment.
A disorder characterized by signs and symptoms related to acute ischemia of the myocardium secondary to coronary artery disease. The clinical presentation covers a spectrum of heart diseases from unstable angina to myocardial infarction.
A disorder characterized by the acute loss of renal function and is traditionally classified as pre-renal (low blood flow into kidney), renal (kidney damage) and post-renal causes (ureteral or bladder outflow obstruction).
A disorder that occurs when the adrenal cortex does not produce enough of the hormone cortisol and in some cases, the hormone aldosterone. It may be due to a disorder of the adrenal cortex as in Addison's disease or primary adrenal insufficiency.
A disorder characterized by progressive and life-threatening pulmonary distress in the absence of an underlying pulmonary condition, usually following major trauma or surgery.
A disorder characterized by a state of restlessness associated with unpleasant feelings of irritability and tension.
A disorder characterized by an uncomfortable feeling of inner restlessness and inability to stay still; this is a side effect of some psychotropic drugs.
A finding based on laboratory test results that indicate an increase in the level of alanine aminotransferase (ALT or SGPT) in the blood specimen.
A disorder characterized by an increase in sensitivity to the adverse effects of alcohol, which can include nasal congestion, skin flushes, heart dysrhythmias, nausea, vomiting, indigestion and headaches.
A finding based on laboratory test results that indicate an increase in the level of alkaline phosphatase in a blood specimen.
A disorder characterized by abnormally high alkalinity (low hydrogen-ion concentration) of the blood and other body tissues.
A disorder characterized by an adverse local or general response from exposure to an allergen.
A disorder characterized by an inflammation of the nasal mucous membranes caused by an IgE-mediated response to external allergens. The inflammation may also involve the mucous membranes of the sinuses, eyes, middle ear, and pharynx. Symptoms include sneezing, nasal congestion, rhinorrhea and itching.
A disorder characterized by a decrease in density of hair compared to normal for a given individual at a given age and body location.
A disorder characterized by systematic and extensive loss of memory.
A disorder characterized by an abnormal communication between the opening in the anal canal to the perianal skin.
A disorder characterized by bleeding from the anal region.
A disorder characterized by inflammation of the mucous membrane of the anus.
A disorder characterized by a necrotic process occurring in the anal region.
A disorder characterized by a sensation of marked discomfort in the anal region.
A disorder characterized by a narrowing of the lumen of the anal canal.
A disorder characterized by a circumscribed, inflammatory and necrotic erosive lesion on the mucosal surface of the anal canal.
A disorder characterized by an acute inflammatory reaction resulting from the release of histamine and histamine-like substances from mast cells, causing a hypersensitivity immune response. Clinically, it presents with breathing difficulty, dizziness, hypotension, cyanosis and loss of consciousness and may lead to death.
A disorder characterized by an reduction in the amount of hemoglobin in 100 ml of blood. Signs and symptoms of anemia may include pallor of the skin and mucous membranes, shortness of breath, palpitations of the heart, soft systolic murmurs, lethargy, and fatigability.
A finding of damage to the ankle joint characterized by a break in the continuity of the ankle bone. Symptoms include marked discomfort, swelling and difficulty moving the affected leg and foot.
A disorder characterized by an infectious process involving the anal area and the rectum.
A disorder characterized by a loss of appetite.
A disorder characterized by an inability to achieve orgasm.
A disorder characterized by apprehension of danger and dread accompanied by restlessness, tension, tachycardia, and dyspnea unattached to a clearly identifiable stimulus.
A disorder characterized by a defect in aortic valve function or structure.
A disorder characterized by the inability to speak. It may result from injuries to the vocal cords or may be functional (psychogenic).
A disorder characterized by cessation of breathing.
A disorder characterized by acute inflammation to the vermiform appendix caused by a pathogenic agent.
A disorder characterized by acute inflammation to the vermiform appendix caused by a pathogenic agent with gangrenous changes resulting in the rupture of the appendiceal wall. The appendiceal wall rupture causes the release of inflammatory and bacterial contents from the appendiceal lumen into the abdominal cavity.
A disorder characterized by inflammation of the arachnoid membrane and adjacent subarachnoid space.
A disorder characterized by an infectious process involving an artery.
A disorder characterized by a sensation of marked discomfort in a joint.
A disorder characterized by inflammation involving a joint.
A disorder characterized by accumulation of serous or hemorrhagic fluid in the peritoneal cavity.
A finding based on laboratory test results that indicate an increase in the level of aspartate aminotransferase (AST or SGOT) in a blood specimen.
A disorder characterized by inhalation of solids or liquids into the lungs.
A disorder characterized by a dysrhythmia without cardiac electrical activity. Typically, this is accompanied by cessation of the pumping function of the heart.
A disorder characterized by lack of coordination of muscle movements resulting in the impairment or inability to perform voluntary activities.
A disorder characterized by the collapse of part or the entire lung.
A disorder characterized by a dysrhythmia without discernible P waves and an irregular ventricular response due to multiple reentry circuits. The rhythm disturbance originates above the ventricles.
A disorder characterized by a dysrhythmia with organized rhythmic atrial contractions with a rate of 200-300 beats per minute. The rhythm disturbance originates in the atria.
A disorder characterized by a dysrhythmia with complete failure of atrial electrical impulse conduction through the AV node to the ventricles.
A disorder characterized by a dysrhythmia with a delay in the time required for the conduction of an electrical impulse through the atrioventricular (AV) node beyond 0.2 seconds; prolongation of the PR interval greater than 200 milliseconds.
A disorder resulting from loss of function or tissue destruction of an organ or multiple organs, arising from humoral or cellular immune responses of the individual to his own tissue constituents.
A disorder characterized by necrotic changes in the bone tissue due to interruption of blood supply. Most often affecting the epiphysis of the long bones, the necrotic changes result in the collapse and the destruction of the bone structure.
A disorder characterized by laboratory test results that indicate complete absence of spermatozoa in the semen.
A disorder characterized by marked discomfort sensation in the back region.
A disorder characterized by a narrowing of the lumen of the bile duct.
A finding of leakage of bile due to breakdown of a biliary anastomosis (surgical connection of two separate anatomic structures).
A disorder characterized by an abnormal communication between the bile ducts and another organ or anatomic site.
A disorder characterized by an infectious process involving the biliary tract.
A finding of leakage of urine due to breakdown of a bladder anastomosis (surgical connection of two separate anatomic structures).
A disorder characterized by an infectious process involving the bladder.
A disorder characterized by a rupture in the bladder wall.
A disorder characterized by a sudden and involuntary contraction of the bladder wall.
A disorder characterized by subject-reported feeling of uncomfortable fullness of the abdomen.
Blood and lymphatic system disorders - Other, Specify
A finding based on laboratory test results that indicate abnormal levels of antidiuretic hormone in the blood specimen.
A finding based on laboratory test results that indicate an abnormally high level of bilirubin in the blood. Excess bilirubin is associated with jaundice.
A finding based on laboratory test results that indicate an decrease in levels of corticotrophin in a blood specimen.
A finding based on laboratory test results that indicate abnormal levels of gonadotrophin hormone in a blood specimen.
A finding based on laboratory test results that indicate abnormal levels of prolactin hormone in a blood specimen.
A disorder characterized by visual perception of unclear or fuzzy images.
A disorder characterized by an abnormal body smell resulting from the growth of bacteria on the body.
A disorder characterized by an infectious process involving the bones.
A disorder characterized by the inability of the bone marrow to produce hematopoietic elements.
A disorder characterized by marked discomfort sensation in the bones.
A disorder characterized by regional paresthesia of the brachial plexus, marked discomfort and muscle weakness, and limited movement in the arm or hand.
A disorder characterized by underdevelopment of the breast.
A disorder characterized by an infectious process involving the breast.
A disorder characterized by marked discomfort sensation in the breast region.
A disorder characterized by an abnormal communication between the bronchus and another organ or anatomic site.
A disorder characterized by an infectious process involving the bronchi.
A disorder characterized by blockage of a bronchus passage, most often by bronchial secretions and exudates.
A disorder characterized by a narrowing of the bronchial tube.
A disorder characterized by an abnormal communication between a bronchus and the pleural cavity.
A disorder characterized by bleeding from the bronchial wall and/or lung parenchyma.
A disorder characterized by a sudden contraction of the smooth muscles of the bronchial wall.
A finding of injury of the soft tissues or bone characterized by leakage of blood into surrounding tissues.
A disorder characterized by inflammation of the skin characterized by the presence of bullae which are filled with fluid.
A finding of impaired integrity to the anatomic site of an adverse thermal reaction. Burns can be caused by exposure to chemicals, direct heat, electricity, flames and radiation. The extent of damage depends on the length and intensity of exposure and time until provision of treatment.
A disorder characterized by marked discomfort sensation in the buttocks.
A disorder characterized by leakage of intravascular fluids into the extravascular space. This syndrome is observed in patients who demonstrate a state of generalized leaky capillaries following shock syndromes, low-flow states, ischemia-reperfusion injuries, toxemias, medications, or poisoning. It can lead to generalized edema and multiple organ failure.
Carbon monoxide diffusing capacity decreased
A finding based on lung function test results that indicate a decrease in the lung capacity to absorb carbon monoxide.
A disorder characterized by cessation of the pumping function of the heart.
A laboratory test result which indicates increased levels of cardiac troponin I in a biological specimen.
A laboratory test result which indicates increased levels of cardiac troponin T in a biological specimen.
A disorder characterized by partial or complete opacity of the crystalline lens of one or both eyes. This results in a decrease in visual acuity and eventual blindness if untreated.
A disorder characterized by an infectious process that arises secondary to catheter use.
A finding based on laboratory test results that indicate an decrease in levels of CD4 lymphocytes in a blood specimen.
A disorder characterized by bleeding from the cecum.
A disorder characterized by an infectious process involving the cecum.
A disorder characterized by a necrotic process occurring in the brain and/or spinal cord.
A disorder characterized by loss of cerebrospinal fluid into the surrounding tissues.
A disorder characterized by an infectious process involving the uterine cervix.
A disorder characterized by inflammation of the lip.
A disorder characterized by substernal discomfort due to insufficient myocardial oxygenation.
A disorder characterized by marked discomfort sensation in the chest wall region.
A disorder characterized by a sensation of cold that often marks a physiologic response to sweating after a fever.
A disorder characterized by inflammation involving the gallbladder. It may be associated with the presence of gallstones.
A finding based on laboratory test results that indicate higher than normal levels of cholesterol in a blood specimen.
A disorder characterized by gradual and usually permanent loss of kidney function resulting in renal failure.
A disorder characterized by milky pleural effusion (abnormal collection of fluid) resulting from accumulation of lymph fluid in the pleural cavity.
A disorder characterized by a conspicuous change in cognitive function.
A disorder characterized by inflammation of the colon.
A disorder characterized by an abnormal communication between the large intestine and another organ or anatomic site.
A disorder characterized by bleeding from the colon.
A disorder characterized by blockage of the normal flow of the intestinal contents in the colon.
A disorder characterized by a rupture in the colonic wall.
A disorder characterized by a narrowing of the lumen of the colon.
A disorder characterized by a circumscribed, inflammatory and necrotic erosive lesion on the mucosal surface of the colon.
A disorder characterized by a deterioration in the ability to concentrate.
A disorder characterized by pathological irregularities in the cardiac conduction system.
A disorder characterized by a lack of clear and orderly thought and behavior.
Congenital, familial and genetic disorders - Other, Specify
A disorder characterized by inflammation, swelling and redness to the conjunctiva of the eye.
A disorder characterized by an infectious process involving the conjunctiva. Clinical manifestations include pink or red color in the eyes.
A disorder characterized by irregular and infrequent or difficult evacuation of the bowels.
A disorder characterized by a thickened and fibrotic pericardial sac; these fibrotic changes impede normal myocardial function by restricting myocardial muscle action.
A disorder characterized by an infectious process involving the cornea.
A disorder characterized by an area of epithelial tissue loss on the surface of the cornea. It is associated with inflammatory cells in the cornea and anterior chamber.
A disorder characterized by sudden, often repetitive, spasmodic contraction of the thoracic cavity, resulting in violent release of air from the lungs and usually accompanied by a distinctive sound.
A finding based on laboratory test results that indicate an increase in levels of creatine phosphokinase in a blood specimen.
A disorder characterized by an infectious process involving a cranial nerve.
A finding based on laboratory test results that indicate increased levels of creatinine in a biological specimen.
A disorder characterized by signs and symptoms that resemble Cushing's disease or syndrome: buffalo hump obesity, striations, adiposity, hypertension, diabetes, and osteoporosis, usually due to exogenous corticosteroids.
A disorder characterized by inflammation of the bladder which is not caused by an infection of the urinary tract.
A disorder characterized by nausea, headache, tachycardia, hypotension, rash, and shortness of breath; it is caused by the release of cytokines from the cells.
A disorder characterized by cessation of life occurring during the first 28 days of life.
A cessation of life that cannot be attributed to a CTCAE term associated with Grade 5.
A disorder characterized by excessive loss of water from the body. It is usually caused by severe diarrhea, vomiting or diaphoresis.
A disorder characterized by sexual dysfunction characterized by a delay in climax.
A disorder characterized by unusually late sexual maturity.
A disorder characterized by the acute and sudden development of confusion, illusions, movement changes, inattentiveness, agitation, and hallucinations. Usually, it is a reversible condition.
A disorder characterized by false personal beliefs held contrary to reality, despite contradictory evidence and common sense.
A disorder characterized by the decay of a tooth, in which it becomes softened, discolored and/or porous.
A disorder characterized by a decrease in ability to perceive and respond.
A disorder characterized by melancholic feelings of grief or unhappiness.
A finding of cutaneous inflammatory reaction occurring as a result of exposure to biologically effective levels of ionizing radiation.
A disorder characterized by an infectious process involving the use of a medical device.
A disorder characterized by frequent and watery bowel movements.
A disorder characterized by systemic pathological activation of blood clotting mechanisms which results in clot formation throughout the body. There is an increase in the risk of hemorrhage as the body is depleted of platelets and coagulation factors.
A disorder characterized by a disturbing sensation of lightheadedness, unsteadiness, giddiness, spinning or rocking.
A disorder characterized by dryness of the cornea and conjunctiva.
A disorder characterized by reduced salivary flow in the oral cavity.
A disorder characterized by flaky and dull skin; the pores are generally fine, the texture is a papery thin texture.
A disorder characterized by an abnormal communication between the duodenum and another organ or anatomic site.
A disorder characterized by bleeding from the duodenum.
A disorder characterized by an infectious process involving the duodenum.
A disorder characterized by blockage of the normal flow of stomach contents through the duodenum.
A disorder characterized by a rupture in the duodenal wall.
A disorder characterized by a narrowing of the lumen of the duodenum.
A disorder characterized by a circumscribed, inflammatory and necrotic erosive lesion on the mucosal surface of the duodenal wall.
A disorder characterized by slow and slurred speech resulting from an inability to coordinate the muscles used in speech.
A disorder characterized by distortion of sensory perception, resulting in an abnormal and unpleasant sensation.
A disorder characterized by abnormal sensual experience with the taste of foodstuffs; it can be related to a decrease in the sense of smell.
A disorder characterized by abnormally painful abdominal cramps during menses.
A disorder characterized by painful or difficult coitus.
A disorder characterized by an uncomfortable, often painful feeling in the stomach, resulting from impaired digestion. Symptoms include burning stomach, bloating, heartburn, nausea and vomiting.
A disorder characterized by difficulty in swallowing.
A disorder characterized by impairment of verbal communication skills, often resulting from brain damage.
A disorder characterized by an uncomfortable sensation of difficulty breathing.
Ear and labyrinth disorders - Other, Specify
A disorder characterized by a sensation of marked discomfort in the ear.
A disorder characterized by swelling due to an excessive accumulation of fluid in the brain.
A disorder characterized by swelling due to excessive fluid accumulation in facial tissues.
A disorder characterized by swelling due to excessive fluid accumulation in the upper or lower extremities.
A disorder characterized by swelling due to excessive fluid accumulation in the trunk area.
A disorder characterized by problems related to ejaculation. This category includes premature, delayed, retrograde and painful ejaculation.
The percentage computed when the amount of blood ejected during a ventricular contraction of the heart is compared to the amount that was present prior to the contraction.
Electrocardiogram QT corrected interval prolonged
A finding of a cardiac dysrhythmia characterized by an abnormally long corrected QT interval.
A disorder characterized by an infectious process involving the brain tissue.
A disorder characterized by an infectious process involving the brain and spinal cord tissues.
A disorder characterized by a pathologic process involving the brain.
A disorder characterized by an infectious process involving the endocardial layer of the heart.
A disorder characterized by an infectious process involving the internal structures of the eye.
A disorder characterized by inflammation of the small and large intestines.
A disorder characterized by an infectious process involving the small and large intestines.
A disorder characterized by an abnormal communication between the urinary bladder and the intestine.
A disorder characterized by bleeding from the nose.
A disorder characterized by the persistent or recurrent inability to achieve or to maintain an erection during sexual activity.
A disorder characterized by target lesions (a pink-red ring around a pale center).
A disorder characterized by generalized inflammatory erythema and exfoliation. The inflammatory process involves > 90% of the body surface area.
A finding of leakage due to breakdown of an esophageal anastomosis (surgical connection of two separate anatomic structures).
A disorder characterized by an abnormal communication between the esophagus and another organ or anatomic site.
A disorder characterized by bleeding from the esophagus.
A disorder characterized by an infectious process involving the esophagus.
A disorder characterized by a necrotic process occurring in the esophageal wall.
A disorder characterized by blockage of the normal flow of the contents in the esophagus.
A disorder characterized by a sensation of marked discomfort in the esophageal region.
A disorder characterized by a rupture in the wall of the esophagus.
A disorder characterized by a narrowing of the lumen of the esophagus.
A disorder characterized by a circumscribed, inflammatory and necrotic erosive lesion on the mucosal surface of the esophageal wall.
A disorder characterized by bleeding from esophageal varices.
A disorder characterized by inflammation of the esophageal wall.
A disorder characterized by an exaggerated feeling of well-being which is disproportionate to events and stimuli.
A disorder characterized by non-neoplastic overgrowth of bone.
A disorder characterized by inflammation, swelling and redness to the outer ear and ear canal.
A disorder characterized by a sensation of marked discomfort in the external ear region.
A disorder characterized by incomplete paralysis of an extraocular muscle.
A disorder characterized by abnormal, repetitive, involuntary muscle movements, frenzied speech and extreme restlessness.
A disorder characterized by an infectious process involving the eye.
A disorder characterized by a sensation of marked discomfort in the eye.
A disorder characterized by impaired eyelid function.
A disorder characterized by a reduction in the strength of the facial muscles.
A disorder characterized by involvement of the facial nerve (seventh cranial nerve).
A disorder characterized by a sensation of marked discomfort in the face.
A finding of sudden movement downward, usually resulting in injury.
A finding of leakage due to breakdown of a fallopian tube anastomosis (surgical connection of two separate anatomic structures).
A disorder characterized by blockage of the normal flow of the contents in the fallopian tube.
A finding of rupture of the fallopian tube wall.
A disorder characterized by a narrowing of the fallopian tube lumen.
A disorder characterized by shrinking of adipose tissue.
A disorder characterized by a state of generalized weakness with a pronounced inability to summon sufficient energy to accomplish daily activities.
A disorder characterized by a decrease in neutrophils associated with fever.
A disorder characterized by inability to control the escape of stool from the rectum.
A disorder characterized by an abnormal communication between a female reproductive system organ and another organ or anatomic site.
A disorder characterized by the development of secondary female sex characteristics in males due to extrinsic factors.
A disorder characterized by death in utero; failure of the product of conception to show evidence of respiration, heartbeat, or definite movement of a voluntary muscle after expulsion from the uterus, without possibility of resuscitation.
A disorder characterized by inhibition of fetal growth resulting in the inability of the fetus to achieve its potential weight.
A disorder characterized by elevation of the body's temperature above the upper limit of normal.
A finding based on laboratory test results that indicate an decrease in levels of fibrinogen in a blood specimen.
A disorder characterized by fibrotic degeneration of the deep connective tissues.
A disorder characterized by marked discomfort sensation on the lateral side of the body in the region below the ribs and above the hip.
A disorder characterized by a sudden or brief burst of light.
A disorder characterized by a state of excessive gas in the alimentary canal.
A disorder characterized by an individual seeing spots before their eyes. The spots are shadows of opaque cell fragments in the vitreous humor or lens.
A disorder characterized by a group of symptoms similar to those observed in patients with the flu. It includes fever, chills, body aches, malaise, loss of appetite and dry cough.
A disorder characterized by episodic reddening of the face.
A finding based on test results that indicate a relative decrease in the fraction of the forced vital capacity that is exhaled in a specific number of seconds.
A finding of traumatic injury to the bone in which the continuity of the bone is broken.
A disorder characterized by walking difficulties.
A disorder characterized by an abnormal communication between the gallbladder and another organ or anatomic site.
A disorder characterized by an infectious process involving the gallbladder.
A disorder characterized by a necrotic process occurring in the gallbladder.
A disorder characterized by blockage of the normal flow of the contents of the gallbladder.
A disorder characterized by a sensation of marked discomfort in the gallbladder region.
A disorder characterized by a rupture in the gallbladder wall.
A finding of leakage due to breakdown of a gastric anastomosis (surgical connection of two separate anatomic structures).
A disorder characterized by an abnormal communication between the stomach and another organ or anatomic site.
A disorder characterized by bleeding from the gastric wall.
A disorder characterized by a necrotic process occurring in the gastric wall.
A disorder characterized by a rupture in the stomach wall.
A disorder characterized by a narrowing of the lumen of the stomach.
A disorder characterized by a circumscribed, inflammatory and necrotic erosive lesion on the mucosal surface of the stomach.
A disorder characterized by inflammation of the stomach.
A disorder characterized by reflux of the gastric and/or duodenal contents into the distal esophagus. It is chronic in nature and usually caused by incompetence of the lower esophageal sphincter, and may result in injury to the esophageal mucosal. Symptoms include heartburn and acid indigestion.
A finding of leakage due to breakdown of a gastrointestinal anastomosis (surgical connection of two separate anatomic structures).
Gastrointestinal disorders - Other, Specify
A disorder characterized by an abnormal communication between any part of the gastrointestinal system and another organ or anatomic site.
A disorder characterized by a sensation of marked discomfort in the gastrointestinal region.
A finding of a necrotic process occurring in the gastrointestinal tract stoma.
A disorder characterized by an incomplete paralysis of the muscles of the stomach wall resulting in delayed emptying of the gastric contents into the small intestine.
General disorders and administration site conditions - Other, Specify
A disorder characterized by a reduction in the strength of muscles in multiple anatomic sites.
A disorder characterized by swelling due to an excessive accumulation of fluid in the genitals.
A finding based on laboratory test results that indicate higher than normal levels of the enzyme gamma-glutamyltransferase in the blood specimen. GGT (gamma-glutamyltransferase ) catalyzes the transfer of a gamma glutamyl group from a gamma glutamyl peptide to another peptide, amino acids or water.
A disorder characterized by a sensation of marked discomfort in the gingival region.
A disorder characterized by an increase in pressure in the eyeball due to obstruction of the aqueous humor outflow.
A disorder characterized by involvement of the glossopharyngeal nerve (ninth cranial nerve).
A disorder characterized by an inability to properly metabolize glucose.
A disorder characterized by greater growth than expected for age.
A finding based on laboratory test results that indicate abnormal levels of growth hormone in a biological specimen.
A disorder characterized by of stature that is smaller than normal as expected for age.
A disorder characterized by an infectious process involving the gums.
A disorder characterized by excessive development of the breasts in males.
A disorder characterized by a false sensory perception in the absence of an external stimulus.
A finding based on laboratory test results that indicate an decrease in levels of haptoglobin in a blood specimen.
A disorder characterized by a necrotic process occurring in the soft tissues of the head.
A disorder characterized by a sensation of marked discomfort in various parts of the head, not confined to the area of distribution of any nerve.
A disorder characterized by partial or complete loss of the ability to detect or understand sounds resulting from damage to ear structures.
A disorder characterized by the inability of the heart to pump blood at an adequate volume to meet tissue metabolic requirements, or, the ability to do so only at an elevation in the filling pressure.
A disorder characterized by a localized collection of blood, usually clotted, in an organ, space, or tissue, due to a break in the wall of a blood vessel.
A disorder characterized by the presence of blood in a fallopian tube.
A disorder characterized by laboratory test results that indicate blood in the urine.
A finding based on laboratory test results that indicate increased levels of hemoglobin in a biological specimen.
A disorder characterized by laboratory test results that indicate the presence of free hemoglobin in the urine.
A disorder characterized by laboratory test results that indicate widespread erythrocyte cell membrane destruction.
A disorder characterized by a form of thrombotic microangiopathy with renal failure, hemolytic anemia, and severe thrombocytopenia.
A disorder characterized by bleeding from the hemorrhoids.
A disorder characterized by the presence of dilated veins in the rectum and surrounding area.
A disorder characterized by the inability of the liver to metabolize chemicals in the body. Laboratory test results reveal abnormal plasma levels of ammonia, bilirubin, lactic dehydrogenase, and alkaline phosphatase.
A disorder characterized by bleeding from the liver.
A disorder characterized by an infectious process involving the liver.
A disorder characterized by a necrotic process occurring in the hepatic parenchyma.
A disorder characterized by a sensation of marked discomfort in the liver region.
A disorder characterized by a viral pathologic process involving the liver parenchyma.
Hepatobiliary disorders - Other, Specify
A disorder characterized by repeated gulp sounds that result from an involuntary opening and closing of the glottis. This is attributed to a spasm of the diaphragm.
A finding of traumatic injury to the hip in which the continuity of either the femoral head, femoral neck, intertrochanteric or subtrochanteric regions is broken.
A disorder characterized by the presence of excess hair growth in women in anatomic sites where growth is considered to be a secondary male characteristic and under androgen control (beard, moustache, chest, abdomen)
A disorder characterized by harsh and raspy voice arising from or spreading to the larynx.
A disorder characterized by an uncomfortable and temporary sensation of intense body warmth, flushing, sometimes accompanied by sweating upon cooling.
A disorder characterized by an abnormal increase of cerebrospinal fluid in the ventricles of the brain.
A disorder characterized by laboratory test results that indicate an elevation in the concentration of calcium in blood.
A disorder characterized by laboratory test results that indicate an elevation in the concentration of blood sugar. It is usually an indication of diabetes mellitus or glucose intolerance.
A disorder characterized by excessive perspiration.
A disorder characterized by laboratory test results that indicate an elevation in the concentration of potassium in the blood; associated with kidney failure or sometimes with the use of diuretic drugs.
A disorder characterized by laboratory test results that indicate an elevation in the concentration of magnesium in the blood.
A disorder characterized by laboratory test results that indicate an elevation in the concentration of sodium in the blood.
A disorder characterized by an increase in production of parathyroid hormone by the parathyroid glands. This results in hypercalcemia (abnormally high levels of calcium in the blood).
A disorder characterized by characterized by excessive sleepiness during the daytime.
A disorder characterized by a pathological increase in blood pressure; a repeatedly elevation in the blood pressure exceeding 140 over 90 mm Hg.
A disorder characterized by excessive levels of thyroid hormone in the body. Common causes include an overactive thyroid gland or thyroid hormone overdose.
A disorder characterized by hair density or length beyond the accepted limits of normal in a particular body region, for a particular age or race.
A disorder characterized by laboratory test results that indicate an elevation in the concentration of triglyceride concentration in the blood.
A disorder characterized by laboratory test results that indicate an elevation in the concentration of uric acid.
A disorder characterized by laboratory test results that indicate a low concentration of albumin in the blood.
A disorder characterized by laboratory test results that indicate a low concentration of calcium in the blood.
A disorder characterized by involvement of the hypoglossal nerve (twelfth cranial nerve).
A disorder characterized by laboratory test results that indicate a low concentration of glucose in the blood.
A disorder characterized by reduced sweating.
A disorder characterized by laboratory test results that indicate a low concentration of potassium in the blood.
A disorder characterized by laboratory test results that indicate a low concentration of magnesium in the blood.
A disorder characterized by laboratory test results that indicate a low concentration of sodium in the blood.
A disorder characterized by a decrease in production of parathyroid hormone by the parathyroid glands.
A disorder characterized by laboratory test results that indicate a low concentration of phosphates in the blood.
A disorder characterized by a blood pressure that is below the normal expected for an individual in a given environment.
A disorder characterized by an abnormally low body temperature. Treatment is required when the body temperature is 35C (95F) or below.
A disorder characterized by a decrease in production of thyroid hormone by the thyroid gland.
A disorder characterized by a decrease in the level of oxygen in the body.
A disorder characterized by an abnormal communication between the ileum and another organ or anatomic site.
A disorder characterized by bleeding from the ileal wall.
A disorder characterized by blockage of the normal flow of the intestinal contents in the ileum.
A disorder characterized by a rupture in the ileal wall.
A disorder characterized by a narrowing of the lumen of the ileum.
A disorder characterized by a circumscribed, inflammatory and necrotic erosive lesion on the mucosal surface of the ileum.
A disorder characterized by failure of the ileum to transport intestinal contents.
Immune system disorders - Other, Specify
Infections and infestations - Other, Specify
A disorder characterized by an infectious process involving the skeletal muscles.
A disorder characterized by adverse reaction to the infusion of pharmacological or biological substances.
A disorder characterized by leakage of a pharmacologic or a biologic substance from the infusion site into the surrounding tissue. Signs and symptoms include induration, erythema, swelling, burning sensation and marked discomfort at the infusion site.
A disorder characterized by an intense adverse reaction (usually immunologic) developing at the site of an injection.
A finding of damage to the carotid artery.
A finding of damage to the inferior vena cava.
A finding of damage to the jugular vein.
A finding of damage to the superior vena cava.
Injury, poisoning and procedural complications - Other, Specify
A finding based on laboratory test results that indicate an increase in the ratio of the patient's prothrombin time to a control sample in the blood.
A disorder characterized by difficulty in falling asleep and/or remaining asleep.
A finding of leakage of contents from an intestinal stoma (surgically created opening on the surface of the body).
A finding of blockage of the normal flow of the contents of the intestinal stoma.
A finding of blood leakage from the intestinal stoma.
A disorder characterized by bleeding in the abdominal cavity.
A disorder characterized by bleeding from the cranium.
A finding of damage to an artery during a surgical procedure.
A finding of damage to the breast parenchyma during a surgical procedure.
A finding of damage to the heart during a surgical procedure.
A finding of damage to the ear during a surgical procedure.
A finding of damage to the endocrine gland during a surgical procedure.
A finding of damage to the gastrointestinal system during a surgical procedure.
A finding of damage to the head and neck during a surgical procedure.
A finding of uncontrolled bleeding during a surgical procedure.
A finding of damage to the hepatic parenchyma and/or biliary tract during a surgical procedure.
A finding of damage to the musculoskeletal system during a surgical procedure.
A finding of damage to the nervous system during a surgical procedure.
A finding of damage to the eye during a surgical procedure.
A finding of damage to the kidney during a surgical procedure.
Intraoperative reproductive tract injury
A finding of damage to the reproductive organs during a surgical procedure.
A finding of damage to the respiratory system during a surgical procedure.
A finding of damage to the skin during a surgical procedure.
A finding of damage to the spleen during a surgical procedure.
A finding of damage to the urinary system during a surgical procedure.
A finding of damage to a vein during a surgical procedure.
A disorder characterized by accumulation of iron in the tissues.
A disorder characterized by irregular cycle or duration of menses.
A disorder characterized by an abnormal responsiveness to stimuli or physiological arousal; may be in response to pain, fright, a drug, an emotional situation or a medical condition.
A disorder characterized by a decrease or absence of blood supply to the brain caused by obstruction (thrombosis or embolism) of an artery resulting in neurological damage.
A disorder characterized by involvement of the trochlear nerve (fourth cranial nerve).
A disorder characterized by an abnormal communication between the jejunum and another organ or anatomic site.
A disorder characterized by bleeding from the jejunal wall.
A disorder characterized by blockage of the normal flow of the intestinal contents in the jejunum.
A disorder characterized by a rupture in the jejunal wall.
A disorder characterized by a narrowing of the lumen of the jejunum.
A disorder characterized by a circumscribed, inflammatory and necrotic erosive lesion on the mucosal surface of the jejunum.
A disorder characterized by excessive fluid in a joint, usually as a result of joint inflammation.
A disorder characterized by an infectious process involving a joint.
A disorder characterized by a decrease in joint flexibility of any joint.
Joint range of motion decreased cervical spine
A disorder characterized by a decrease in flexibility of a cervical spine joint.
Joint range of motion decreased lumbar spine
A disorder characterized by a decrease in flexibility of a lumbar spine joint.
A disorder characterized by inflammation to the cornea of the eye.
A finding of leakage of urine due to breakdown of a kidney anastomosis (surgical connection of two separate anatomic structures).
A disorder characterized by an infectious process involving the kidney.
A disorder characterized by an abnormal increase in the curvature of the thoracic portion of the spine.
A disorder characterized by disturbances of milk secretion. It is not necessarily related to pregnancy that is observed in females and can be observed in males.
A finding of leakage due to breakdown of an anastomosis (surgical connection of two separate anatomic structures) in the large intestine.
A disorder characterized by swelling due to an excessive accumulation of fluid in the larynx.
A disorder characterized by an abnormal communication between the larynx and another organ or anatomic site.
A disorder characterized by bleeding from the larynx.
A disorder characterized by an inflammation involving the larynx.
A disorder characterized by an inflammation involving the mucous membrane of the larynx.
A disorder characterized by blockage of the laryngeal airway.
A disorder characterized by a narrowing of the laryngeal airway.
A disorder characterized by an inflammatory process involving the larynx.
A disorder characterized by an uncomfortable persistent sensation in the area of the laryngopharynx.
A disorder characterized by paroxysmal spasmodic muscular contraction of the vocal cords.
A disorder characterized by failure of the left ventricle to produce adequate output despite an increase in distending pressure and in end-diastolic volume. Clinical manifestations mayinclude dyspnea, orthopnea, and other signs and symptoms of pulmonary congestion and edema.
A disorder characterized by a decrease in consciousness characterized by mental and physical inertness.
Leukemia secondary to oncology chemotherapy
A disorder characterized by leukemia arising as a result of the mutagenic effect of chemotherapy agents.
A disorder characterized by laboratory test results that indicate an increased number of white blood cells in the blood.
A disorder characterized by diffuse reactive astrocytosis with multiple areas of necrotic foci without inflammation.
A disorder characterized by a decrease in sexual desire.
A disorder characterized by an increase in sexual desire.
A disorder characterized by an infectious process involving the lips.
A disorder characterized by a sensation of marked discomfort of the lip.
A finding based on laboratory test results that indicate an increase in the level of lipase in a biological specimen.
A disorder characterized by hypertrophy of the subcutaneous adipose tissue at the site of multiple subcutaneous injections of insulin.
A disorder characterized by swelling due to excessive fluid accumulation at a specific anatomic site.
A disorder characterized by an abnormal increase in the curvature of the lumbar portion of the spine.
A disorder characterized by bleeding from the lower gastrointestinal tract (small intestine, large intestine, and anus).
A disorder characterized by an infectious process involving the lungs.
A disorder characterized by an infectious process involving the lymph nodes.
A disorder characterized by the loss of lymph fluid into the surrounding tissue or body cavity.
A disorder characterized by a sensation of marked discomfort in a lymph node.
A disorder characterized by excessive fluid collection in tissues that causes swelling.
A disorder characterized by a cystic lesion containing lymph.
A finding based on laboratory test results that indicate a decrease in number of lymphocytes in a blood specimen.
A finding based on laboratory test results that indicate an abnormal increase in the number of lymphocytes in the blood, effusions or bone marrow.
A disorder characterized by inadequate absorption of nutrients in the small intestine. Symptoms include abdominal marked discomfort, bloating and diarrhea.
A disorder characterized by a feeling of general discomfort or uneasiness, an out-of-sorts feeling.
A disorder characterized by excitement of psychotic proportions manifested by mental and physical hyperactivity, disorganization of behavior and elevation of mood.
A disorder characterized by bleeding from the mediastinum.
A disorder characterized by an infectious process involving the mediastinum.
A disorder characterized by a deterioration in memory function.
A disorder characterized by neck stiffness, headache, and photophobia resulting from irritation of the cerebral meninges.
A disorder characterized by acute inflammation of the meninges of the brain and/or spinal cord.
A disorder characterized by the permanent cessation of menses, usually defined by 12 consecutive months of amenorrhea in a woman over 45 years of age.
A disorder characterized by abnormally heavy vaginal bleeding during menses.
Metabolism and nutrition disorders - Other, Specify
A disorder characterized by inflammation (physiologic response to irritation), swelling and redness to the middle ear.
A disorder characterized by a defect in mitral valve function or structure.
A disorder characterized by a dysrhythmia with relatively constant PR interval prior to the block of an atrial impulse. This is the result of intermittent failure of atrial electrical impulse conduction through the atrioventricular (AV) node to the ventricles.
A disorder characterized by a dysrhythmia with a progressively lengthening PR interval prior to the blocking of an atrial impulse. This is the result of intermittent failure of atrial electrical impulse conduction through the atrioventricular (AV) node to the ventricles.
A disorder characterized by uncontrolled and purposeless movements.
A disorder characterized by an infectious process involving a mucosal surface.
A disorder characterized by inflammation of the oral mucosal.
A disorder characterized by progressive deterioration of the lungs, liver, kidney and clotting mechanisms.
A disorder characterized by a reduction in the strength of the muscles on the left side of the body.
A disorder characterized by a reduction in the strength of the lower limb muscles.
A disorder characterized by a reduction in the strength of the muscles on the right side of the body.
A disorder characterized by a reduction in the strength of the trunk muscles.
A disorder characterized by a reduction in the strength of the upper limb muscles.
Musculoskeletal and connective tissue disorders - Other, Specify
Musculoskeletal and connective tissue disorder - Other, specify
A disorder characterized by of a malformation of the musculoskeletal system.
A disorder characterized by marked discomfort sensation originating from a muscle or group of muscles.
A disorder characterized by inflammation involving the spinal cord. Symptoms include weakness, paresthesia, sensory loss, marked discomfort and incontinence.
A disorder characterized by insufficiently healthy hematapoietic cell production by the bone marrow.
A disorder characterized by gross necrosis of the myocardium; this is due to an interruption of blood supply to the area.
A disorder characterized by inflammation of the muscle tissue of the heart.
A disorder characterized by inflammation involving the skeletal muscles.
A disorder characterized by a change in the color of the nail plate.
A disorder characterized by an infectious process involving the nail.
A disorder characterized by loss of all or a portion of the nail.
A disorder characterized by vertical or horizontal ridges on the nails.
A disorder characterized by obstruction of the nasal passage due to mucosal edema.
A disorder characterized by a queasy sensation and/or the urge to vomit.
A disorder characterized by swelling due to an accumulation of excessive fluid in the neck.
A disorder characterized by marked discomfort sensation in the neck area.
A disorder characterized by a necrotic process occurring in the soft tissues of the neck.
Neoplasms benign, malignant and unspecified (incl cysts and polyps) - Other, Specify
Nervous system disorders - Other, Specify
A disorder characterized by intense painful sensation along a nerve or group of nerves.
A finding based on laboratory test results that indicate a decrease in number of neutrophils in a blood specimen.
A disorder characterized by an inability to see clearly in dim light.
A disorder characterized by a malformation of the nipple.
A disorder characterized by discomfort in the chest unrelated to a heart disorder.
A disorder characterized by involuntary movements of the eyeballs.
A disorder characterized by having a high amount of body fat.
A disorder characterized by blockage of the normal flow of the contents in the stomach.
A disorder characterized by involvement of the oculomotor nerve (third cranial nerve).
A disorder characterized by involvement of the olfactory nerve (first cranial nerve).
A disorder characterized by a decrease in the number of spermatozoa in the semen.
A disorder characterized by involvement of the optic nerve (second cranial nerve).
A disorder characterized by an abnormal communication between the oral cavity and another organ or anatomic site.
A disorder characterized by a burning or tingling sensation on the lips, tongue or entire mouth.
A disorder characterized by bleeding from the mouth.
A disorder characterized by a sensation of marked discomfort in the mouth, tongue or lips.
A disorder characterized by a necrotic process occurring in the bone of the mandible.
A disorder characterized by reduced bone mass, with a decrease in cortical thickness and in the number and size of the trabeculae of cancellous bone (but normal chemical composition), resulting in increased fracture incidence.
A disorder characterized by an infectious process involving the outer ear and ear canal. Contributory factors include excessive water exposure (swimmer's ear infection) and cuts in the ear canal. Symptoms include fullness, itching, swelling and marked discomfort in the ear and ear drainage.
A disorder characterized by an infectious process involving the middle ear.
A disorder characterized by bleeding from the ovary.
A disorder characterized by an infectious process involving the ovary.
A disorder characterized by tearing or disruption of the ovarian tissue.
A disorder characterized by marked discomfort sensation in one side of the abdomen between menstrual cycles, around the time of the discharge of the ovum from the ovarian follicle.
A disorder characterized by the sensation of marked discomfort, distress or agony.
A disorder characterized by marked discomfort sensation in the upper or lower extremities.
A disorder characterized by marked discomfort sensation in the skin.
Palmar-plantar erythrodysesthesia syndrome
A disorder characterized by redness, marked discomfort, swelling, and tingling in the palms of the hands or the soles of the feet.
A disorder characterized by an unpleasant sensation of irregular and/or forceful beating of the heart.
A disorder characterized by an infectious process involving the pancreas.
A finding of leakage due to breakdown of a pancreatic anastomosis (surgical connection of two separate anatomic structures).
A disorder characterized by a narrowing of the lumen of the pancreatic duct.
A finding based on laboratory test results that indicate an decrease in levels of pancreatic enzymes in a biological specimen.
A disorder characterized by an abnormal communication between the pancreas and another organ or anatomic site.
A disorder characterized by bleeding from the pancreas.
A disorder characterized by a necrotic process occurring in the pancreas.
A disorder characterized by inflammation of the pancreas.
A disorder characterized by swelling around the optic disc.
A disorder characterized by an eruption consisting of papules (a small, raised pimple) and pustules (a small pus filled blister), typically appearing in face, scalp, and upper chest and back Unlike acne, this rash does not present with whiteheads or blackheads, and can be symptomatic, with itchy or tender lesions.
A disorder characterized by functional disturbances of sensory neurons resulting in abnormal cutaneous sensations of tingling, numbness, pressure, cold, and warmth that are experienced in the absence of a stimulus.
A disorder characterized by an infectious process involving the soft tissues around the nail.
A disorder characterized by a dysrhythmia with abrupt onset and sudden termination of atrial contractions with a rate of 150-250 beats per minute. The rhythm disturbance originates in the atria.
A disorder characterized by a reduction in the strength of the muscles of the pelvic floor.
A disorder characterized by an infectious process involving the pelvic cavity.
A disorder characterized by marked discomfort sensation in the pelvis.
A disorder characterized by a necrotic process occurring in the soft tissues of the pelvis.
A disorder characterized by an infectious process involving the penis.
A disorder characterized by marked discomfort sensation in the penis.
A disorder characterized by a rupture in the wall of the extrahepatic or intrahepatic bile duct.
A disorder characterized by fluid collection within the pericardial sac, usually due to inflammation.
A disorder characterized by an increase in intrapericardial pressure due to the collection of blood or fluid in the pericardium.
A disorder characterized by irritation to the layers of the pericardium (the protective sac around the heart).
A disorder characterized by a sensation of marked discomfort in the area between the genital organs and the anus.
A disorder in the gingival tissue around the teeth.
A disorder characterized by swelling due to an excessive accumulation of fluid around the orbits of the face.
A disorder characterized by an infectious process involving the orbit of the eye.
A disorder characterized by impaired circulation to an extremity.
A disorder characterized by inflammation or degeneration of the peripheral motor nerves.
A disorder characterized by an infectious process involving the peripheral nerves.
A disorder characterized by inflammation or degeneration of the peripheral sensory nerves.
A disorder characterized by an infectious process involving the peritoneum.
A disorder characterized by a necrotic process occurring in the peritoneum.
A disorder characterized by a conspicuous change in a person's behavior and thinking.
A disorder characterized by marked discomfort related to a limb or an organ that is removed from or is not physically part of the body.
A finding of leakage due to breakdown of a pharyngeal anastomosis (surgical connection of two separate anatomic structures).
A disorder characterized by an abnormal communication between the pharynx and another organ or anatomic site.
A disorder characterized by bleeding from the pharynx.
A disorder characterized by an inflammation involving the mucous membrane of the pharynx.
A disorder characterized by a necrotic process occurring in the pharynx.
A disorder characterized by a narrowing of the pharyngeal airway.
A disorder characterized by inflammation of the throat.
A disorder characterized by marked discomfort sensation in the pharyngolaryngeal region.
A disorder characterized by inflammation of the wall of a vein.
A disorder characterized by an infectious process involving the vein. Clinical manifestations include erythema, marked discomfort, swelling, and induration along the course of the infected vein.
A disorder characterized by fear and avoidance of light.
A disorder characterized by an increase in sensitivity of the skin to light.
A finding based on laboratory test results that indicate a decrease in number of platelets in a blood specimen.
A disorder characterized by an increase in amounts of fluid within the pleural cavity. Symptoms include shortness of breath, cough and marked chest discomfort.
A disorder characterized by bleeding from the pleural cavity.
A disorder characterized by an infectious process involving the pleura.
A disorder characterized by marked discomfort sensation in the pleura.
A disorder characterized by inflammation focally or diffusely affecting the lung parenchyma.
A disorder characterized by abnormal presence of air in the pleural cavity resulting in the collapse of the lung.
A disorder characterized by an increase in blood pressure in the portal venous system.
A disorder characterized by the formation of a thrombus (blood clot) in the portal vein.
A disorder characterized by excessive mucous secretion in the back of the nasal cavity or throat, causing sore throat and/or coughing.
A finding of bleeding occurring after a surgical procedure.
Postoperative thoracic procedure complication
A finding of a previously undocumented problem that occurs after a thoracic procedure.
A disorder characterized by unusually early development of secondary sexual features; the onset of sexual maturation begins usually before age 8 for girls and before age 9 for boys.
Pregnancy, puerperium and perinatal conditions - Other, Specify
A disorder characterized by delivery of a viable infant before the normal end of gestation. Typically, viability is achievable between the twentieth and thirty-seventh week of gestation.
A disorder characterized by ovarian failure before the age of 40. Symptoms include hot flashes, night sweats, mood swings and a decrease in sex drive.
A disorder characterized by an episode of lightheadedness and dizziness which may precede an episode of syncope.
A disorder characterized by inflammation of the rectum.
A disorder characterized by expectorated secretions upon coughing.
A finding of protrusion of the intestinal stoma (surgically created opening on the surface of the body) above the abdominal surface.
A finding of displacement of the urostomy.
A disorder characterized by an infectious process involving the prostate gland.
A disorder characterized by bleeding from the prostate gland.
A disorder characterized by compression of the urethra secondary to enlargement of the prostate gland. This results in voiding difficulties (straining to void, slow urine stream, and incomplete emptying of the bladder).
A disorder characterized by a sensation of marked discomfort in the prostate gland.
A disorder characterized by laboratory test results that indicate the presence of excessive protein in the urine. It is predominantly albumin, but also globulin.
A disorder characterized by an intense itching sensation.
A disorder characterized by personality change, impaired functioning, and loss of touch with reality. It may be a manifestation of schizophrenia, bipolar disorder or brain tumor.
A disorder characterized by accumulation of fluid in the lung tissues that causes a disturbance of the gas exchange that may lead to respiratory failure.
A disorder characterized by the replacement of the lung tissue by connective tissue, leading to progressive dyspnea, respiratory failure or right heart failure.
A disorder characterized by an abnormal communication between the lung and another organ or anatomic site.
A disorder characterized by an increase in pressure within the pulmonary circulation due to lung or heart disorder.
A disorder characterized by a defect in pulmonary valve function or structure.
A disorder characterized by hemorrhagic areas of the skin and mucous membrane. Newer lesions appear reddish in color. Older lesions are usually a darker purple color and eventually become a brownish-yellow color.
A disorder characterized by dysfunction of the corticospinal (pyramidal) tracts of the spinal cord. Symptoms include an increase in the muscle tone in the lower extremities, hyperreflexia, positive Babinski and a decrease in fine motor coordination.
Radiation recall reaction (dermatologic)
A finding of acute skin inflammatory reaction caused by drugs, especially chemotherapeutic agents, for weeks or months following radiotherapy. The inflammatory reaction is confined to the previously irradiated skin and the symptoms disappear after the removal of the pharmaceutical agent.
A disorder characterized by inflammation involving a nerve root. Patients experience marked discomfort radiating along a nerve path because of spinal pressure on the connecting nerve root.
A disorder characterized by an eruption of papules and pustules, typically appearing in face, scalp, upper chest and back.
A disorder characterized by the presence of macules (flat) and papules (elevated). Also known as morbillform rash, it is one of the most common cutaneous adverse events, frequently affecting the upper trunk, spreading centripetally and associated with pruritus.
A disorder characterized by a circumscribed and elevated skin lesion filled with pus.
A finding of leakage due to breakdown of a rectal anastomosis (surgical connection of two separate anatomic structures).
A disorder characterized by an abnormal communication between the rectum and another organ or anatomic site.
A disorder characterized by bleeding from the rectal wall and discharged from the anus.
A disorder characterized by inflammation of the mucous membrane of the rectum.
A disorder characterized by a necrotic process occurring in the rectal wall.
A disorder characterized by blockage of the normal flow of the intestinal contents in the rectum.
A disorder characterized by a sensation of marked discomfort in the rectal region.
A disorder characterized by a rupture in the rectal wall.
A disorder characterized by a narrowing of the lumen of the rectum.
A disorder characterized by a circumscribed, inflammatory and necrotic erosive lesion on the mucosal surface of the rectum.
A disorder characterized by paralysis of the recurrent laryngeal nerve.
Renal and urinary disorders - Other, Specify
A disorder characterized by the formation of crystals in the pelvis of the kidney.
A disorder characterized by paroxysmal and severe flank marked discomfort radiating to the inguinal area. Often, the cause is the passage of kidney stones.
A disorder characterized by bleeding from the kidney.
Reproductive system and breast disorders - Other, Specify
A disorder characterized by impaired gas exchange by the respiratory system resulting in hypoxemia and a decrease in oxygenation of the tissues that may be associated with an increase in arterial levels of carbon dioxide.
Respiratory, thoracic and mediastinal disorders - Other, Specify
A disorder characterized by an inability to rest, relax or be still.
A disorder characterized by an inability of the ventricles to fill with blood because the myocardium (heart muscle) stiffens and loses its flexibility.
A disorder characterized by the separation of the inner retina layers from the underlying pigment epithelium.
A disorder characterized by a small laceration of the retina, this occurs when the vitreous separates from the retina. Symptoms include flashes and floaters.
A disorder characterized by pathological retinal blood vessels that adversely affects vision.
A disorder characterized by weight gain, dyspnea, pleural and pericardial effusions, leukocytosis and/or renal failure originally described in patients treated with all-trans retinoic acid.
A disorder characterized by bleeding from the retroperitoneal area.
Reversible posterior leukoencephalopathy syndrome
A disorder characterized by headaches, mental status changes, visual disturbances, and seizures associated with imaging findings of posterior leukoencephalopathy. It has been observed in association with hypertensive encephalopathy, eclampsia, and immunosuppressive and cytotoxic drug treatment. It is an acute or subacute reversible condition.
A disorder characterized by an infectious process involving the nasal mucosal.
A disorder characterized by impairment of right ventricular function associated with low ejection fraction and a decrease in motility of the right ventricular wall.
A disorder characterized by inflammation of the salivary duct.
A disorder characterized by an abnormal communication between a salivary gland and another organ or anatomic site.
A disorder characterized by an infectious process involving the salivary gland.
A disorder characterized by marked discomfort sensation in the skin covering the top and the back of the head.
A disorder characterized by involvement of the sclera of the eye.
A disorder characterized by a malformed, lateral curvature of the spine.
A disorder characterized by an infectious process involving the scrotum.
A disorder characterized by marked discomfort sensation in the scrotal area.
A disorder characterized by a sudden, involuntary skeletal muscular contractions of cerebral or brain stem origin.
A disorder characterized by the presence of pathogenic microorganisms in the blood stream that cause a rapidly progressing systemic reaction that may lead to shock.
A finding of tumor-like collection of serum in the tissues.
A finding based on laboratory test results that indicate an increase in the levels of amylase in a serum specimen.
A disorder characterized by a delayed-type hypersensitivity reaction to foreign proteins derived from an animal serum. It occurs approximately six to twenty-one days following the administration of the foreign antigen. Symptoms include fever, arthralgias, myalgias, skin eruptions, lymphadenopathy, chest marked discomfort and dyspnea.
A disorder characterized by a dysrhythmia with alternating periods of bradycardia and atrial tachycardia accompanied by syncope, fatigue and dizziness.
A disorder characterized by a dysrhythmia with a heart rate less than 60 beats per minute that originates in the sinus node.
A disorder characterized by involvement of the paranasal sinuses.
A disorder characterized by marked discomfort in the face, between the eyes, or upper teeth originating from the sinuses.
A disorder characterized by a dysrhythmia with a heart rate greater than 100 beats per minute that originates in the sinus node.
A disorder characterized by an infectious process involving the mucous membranes of the paranasal sinuses.
Skin and subcutaneous tissue disorders - Other, Specify
A disorder characterized by the degeneration and thinning of the epidermis and dermis.
A disorder characterized by darkening of the skin due to excessive melanin deposition.
A disorder characterized by loss of skin pigment.
A disorder characterized by an area of hardness in the skin.
A disorder characterized by an infectious process involving the skin.
A disorder characterized by circumscribed, inflammatory and necrotic erosive lesion on the skin.
A disorder characterized by cessation of breathing for short periods during sleep.
A finding of leakage due to breakdown of an anastomosis (surgical connection of two separate anatomic structures) in the small bowel.
A disorder characterized by inflammation of the mucous membrane of the small intestine.
A disorder characterized by blockage of the normal flow of the intestinal contents.
A disorder characterized by a rupture in the small intestine wall.
A disorder characterized by a narrowing of the lumen of the small intestine.
A disorder characterized by an infectious process involving the small intestine.
A disorder characterized by a circumscribed, inflammatory and necrotic erosive lesion on the mucosal surface of the small intestine.
A disorder characterized by the involuntary expulsion of air from the nose.
A disorder characterized by an infectious process involving soft tissues.
A disorder characterized by a necrotic process occurring in the soft tissues of the lower extremity.
A disorder characterized by a necrotic process occurring in the soft tissues of the upper extremity.
A disorder characterized by characterized by excessive sleepiness and drowsiness.
A disorder characterized by of marked discomfort in the throat
A disorder characterized by increased involuntary muscle tone that affects the regions interfering with voluntary movement. It results in gait, movement, and speech disturbances.
A finding of leakage due to breakdown of a spermatic cord anastomosis (surgical connection of two separate anatomic structures).
A disorder characterized by bleeding from the spermatic cord.
A disorder characterized by blockage of the normal flow of the contents of the spermatic cord.
A finding of traumatic injury to the spine in which the continuity of a vertebral bone is broken.
A disorder characterized by an infectious process involving the spleen.
A finding of narrowing of the gastrointestinal stoma (surgically created opening on the surface of the body).
A disorder characterized by less than 10% total body skin area separation of dermis. The syndrome is thought to be a hypersensitivity complex affecting the skin and the mucous membranes.
A disorder characterized by an infectious process involving a stoma (surgically created opening on the surface of the body).
A disorder characterized by a sensation of marked discomfort in the stomach.
A disorder characterized by a circumscribed, inflammatory and necrotic erosive lesion on the jejunal mucosal surface close to the anastomosis site following a gastroenterostomy procedure.
A disorder characterized by a high pitched breathing sound due to laryngeal or upper airway obstruction.
A disorder characterized by a sudden loss of sensory function due to an intracranial vascular event.
An unexpected cessation of life that cannot be attributed to a CTCAE term associated with Grade 5.
A disorder characterized by thoughts of taking one's own life.
A disorder characterized by self-inflicted harm in an attempt to end one's own life.
A disorder characterized by fibrotic degeneration of the superficial soft tissues.
A disorder characterized by a blood clot and inflammation involving a superficial vein of the extremities.
A disorder characterized by obstruction of the blood flow in the superior vena cava. Signs and symptoms include swelling and cyanosis of the face, neck, and upper arms, cough, orthopnea and headache.
A disorder characterized by a dysrhythmia with a heart rate greater than 100 beats per minute that originates above the ventricles.
Surgical and medical procedures - Other, Specify
A disorder characterized by spontaneous loss of consciousness caused by insufficient blood supply to the brain.
A disorder characterized by local dilatation of small vessels resulting in red discoloration of the skin or mucous membranes.
A disorder characterized by involvement of the testis.
A disorder characterized by bleeding from the testis.
A disorder characterized by a sensation of marked discomfort in the testis.
A disorder characterized by occlusion of a vessel by a thrombus that has migrated from a distal site via the blood stream.
A disorder characterized by the presence of microangiopathic hemolytic anemia, thrombocytopenic purpura, fever, renal abnormalities and neurological abnormalities such as seizures, hemiplegia, and visual disturbances. It is an acute or subacute condition.
A disorder characterized by noise in the ears, such as ringing, buzzing, roaring or clicking.
A disorder characterized by a pathological process of the teeth occurring during tooth development.
A disorder characterized by a change in tooth hue or tint.
A disorder characterized by an infectious process involving a tooth.
A disorder characterized by a sensation of marked discomfort in the tooth.
A disorder characterized by greater than 30% total body skin area separation of dermis. The syndrome is thought to be a hypersensitivity complex affecting the skin and the mucous membranes.
A disorder characterized by an abnormal communication between the trachea and another organ or anatomic site.
A disorder characterized by an inflammation involving the mucous membrane of the trachea.
A finding of blockage of the lumen of the trachea.
A disorder characterized by a narrowing of the trachea.
A disorder characterized by an infectious process involving the trachea.
A finding of blood leakage from the tracheostomy site.
A disorder characterized by a brief attack (less than 24 hours) of cerebral dysfunction of vascular origin, with no persistent neurological deficit.
A disorder characterized by development of a malignancy most probably as a result of treatment for a previously existing malignancy.
A disorder characterized by the uncontrolled shaking movement of the whole body or individual parts.
A disorder characterized by a defect in tricuspid valve function or structure.
A disorder characterized by involvement of the trigeminal nerve (fifth cranial nerve).
A disorder characterized by lack of ability to open the mouth fully due to a decrease in the range of motion of the muscles of mastication.
A disorder characterized by metabolic abnormalities that result from a spontaneous or therapy-related cytolysis of tumor cells.
A disorder characterized by marked discomfort from a neoplasm that may be pressing on a nerve, blocking blood vessels, inflamed or fractured from metastasis.
A disorder characterized by inflammation of the cecum.
A disorder characterized by of a discrepancy between the lengths of the lower or upper extremities.
A disorder characterized by an unexpected pregnancy at the time of conception.
A disorder characterized by bleeding from the upper gastrointestinal tract (oral cavity, pharynx, esophagus, and stomach).
A disorder characterized by an infectious process involving the upper respiratory tract (nose, paranasal sinuses, pharynx, larynx, or trachea).
A finding of leakage due to breakdown of a ureteral anastomosis (surgical connection of two separate anatomic structures).
A finding of leakage due to breakdown of a urethral anastomosis (surgical connection of two separate anatomic structures).
A disorder characterized by an infectious process involving the urethra.
A disorder characterized by an abnormal communication between any part of the urinary system and another organ or anatomic site.
A disorder characterized by urination at short intervals.
A disorder characterized by inability to control the flow of urine from the bladder.
A disorder characterized by accumulation of urine within the bladder because of the inability to urinate.
A disorder characterized by an infectious process involving the urinary tract, most commonly the bladder and the urethra.
A disorder characterized by blockage of the normal flow of contents of the urinary tract.
A disorder characterized by a sensation of marked discomfort in the urinary tract.
A disorder characterized by a sudden compelling urge to urinate.
A disorder characterized by a change in the color of the urine.
A finding based on test results that indicate urine production is less relative to previous output.
A finding of leakage of contents from a urostomy.
A finding of bleeding from the urostomy site.
A finding of narrowing of the opening of a urostomy.
A disorder characterized by an itchy skin eruption characterized by wheals with pale interiors and well-defined red margins.
A finding of leakage due to breakdown of a uterine anastomosis (surgical connection of two separate anatomic structures).
A disorder characterized by an abnormal communication between the uterus and another organ or anatomic site.
A disorder characterized by bleeding from the uterus.
A disorder characterized by an infectious process involving the endometrium. It may extend to the myometrium and parametrial tissues.
A disorder characterized by blockage of the uterine outlet.
A disorder characterized by a sensation of marked discomfort in the uterus.
A disorder characterized by a rupture in the uterine wall.
A disorder characterized by inflammation to the uvea of the eye.
A finding of leakage due to breakdown of a vaginal anastomosis (surgical connection of two separate anatomic structures).
A disorder characterized by vaginal secretions. Mucus produced by the cervical glands is discharged from the vagina naturally, especially during the childbearing years.
A disorder characterized by an uncomfortable feeling of itching and burning in the vagina.
A disorder characterized by an abnormal communication between the vagina and another organ or anatomic site.
A disorder characterized by bleeding from the vagina.
A disorder characterized by an infectious process involving the vagina.
A disorder characterized by inflammation involving the vagina. Symptoms may include redness, edema, marked discomfort and an increase in vaginal discharge.
A disorder characterized by blockage of vaginal canal.
A disorder characterized by a sensation of marked discomfort in the vagina.
A disorder characterized by a rupture in the vaginal wall.
A disorder characterized by a narrowing of the vaginal canal.
A disorder characterized by involuntary spasms of the pelvic floor muscles, resulting in pathologic tightness of the vaginal wall during penetration such as during sexual intercourse.
A disorder characterized by involvement of the vagus nerve (tenth cranial nerve).
A finding of leakage due to breakdown of a vas deferens anastomosis (surgical connection of two separate anatomic structures).
A finding of a previously undocumented problem related to the vascular access site.
A disorder characterized by inflammation involving the wall of a vessel.
A disorder characterized by a sudden drop of the blood pressure, bradycardia, and peripheral vasodilation that may lead to loss of consciousness. It results from an increase in the stimulation of the vagus nerve.
A disorder characterized by a dysrhythmia that originates in the ventricles.
A disorder characterized by a dysrhythmia without discernible QRS complexes due to rapid repetitive excitation of myocardial fibers without coordinated contraction of the ventricles.
A disorder characterized by a dysrhythmia with a heart rate greater than 100 beats per minute that originates distal to the bundle of His.
A disorder characterized by a sensation as if the external world were revolving around the patient (objective vertigo) or as if he himself were revolving in space (subjective vertigo).
A disorder characterized by dizziness, imbalance, nausea, and vision problems.
A disorder characterized by inappropriate masculinization occurring in a female or prepubertal male.
A disorder characterized by a decrease in blood supply due to narrowing or blockage of a visceral (mesenteric) artery.
A finding based on pulmonary function test results that indicate an abnormal vital capacity (amount of exhaled after a maximum inhalation) when compared to the predicted value.
A disorder characterized by blood extravasation into the vitreous humor.
A disorder characterized by a change in the sound and/or speed of the voice.
A disorder characterized by the reflexive act of ejecting the contents of the stomach through the mouth.
A disorder characterized by an infectious process involving the vulva.
A disorder of excessive tearing in the eyes; it can be caused by overproduction of tears or impaired drainage of the tear duct.
A finding characterized by an increase in overall body weight; for pediatrics, greater than the baseline growth curve.
A finding characterized by a decrease in overall body weight; for pediatrics, less than the baseline growth curve.
A disorder characterized by a high-pitched, whistling sound during breathing. It results from the narrowing or obstruction of the respiratory airways.
A finding based on laboratory test results that indicate an decrease in number of white blood cells in a blood specimen.
A disorder characterized by the presence of an accessory conductive pathway between the atria and the ventricles that causes premature ventricular activation.
A finding of development of a new problem at the site of an existing wound.
A finding of separation of the approximated margins of a surgical wound.
A disorder characterized by an infectious process involving the wound.
A finding of traumatic injury to the wrist joint in which the continuity of a wrist bone is broken.
An adverse event that is asymptomatic; or involves mild or minor symptoms; or is of marginal clinical relevance; or consists of clinical or diagnostic observations alone; or for which intervention is not indicated; or for which only non-prescription intervention is indicated.
An adverse event for which only minimal, local, or noninvasive intervention (e.g. packing, cautery) is indicated; or that limits instrumental activities of daily living (ADLs, e.g., shopping, laundry, transportation, or ability to conduct finances).
An adverse event that is medically significant but not life-threatening; or for which inpatient care or prolongation of hospitalization are indicated; or that is an important medical event that does not result in hospitalization, but may jeopardize the patient or may require intervention either to prevent hospitalization, to prevent the AE from becoming life-threatening or causing death; or that is disabling; or that results in persistent or significant disability, incapcity, or limitation of self care activities of daily living (ADLs, e.g., getting in and our of bed, dressing, eating, getting around inside, bathing, or using the toilet).
An adverse event that has life-threatening consequences; for which urgent intervention is indicated; that puts the patient at risk of death at the time of the event if immediate intervention is not undertaken; or that causes blindness or deafness.
The termination of life associated with an adverse event.
The affirmative response to a question or activity.
The non-affirmative response to a question.
Biological therapy is a form of treatment that implies the administration of substances which produce a biological reaction in the organism enhancing or restoring the host immune response, modifying the behavior of cancer cells, blocking the pathways of cell neoplastic transformation and tumor ability to metastasize, or facilitating the repairment of cells damaged by aggressive forms of cancer treatment. It includes the use of sera, antitoxins, vaccines, genes, cells, tissues, and organs
A pharmaceutical agent other than agent(s) tested in a given protocol that is administered to or used by a subject either prior to or during the study. Supportive care and essential ancillary medications required by a treatment regimen should be clearly identified. A protocol complete instructions including appropriate indication, dosage, administration route, schedule, restrictions to use, and any other relevant data should be explicitly stated. Concept also refers to substance(s) used prior or during the study that are not specified by the protocol.
Medical device - any machinery designed to aid diagnostic and medical therapies. Medical device has to be designed with rigorous safety standards. There are several basic types of medical devices: life support equipment used to maintain a patient's body functions; therapeutic equipment; monitors and detectors to measure the indexes of a patient's state; imagine machines and laboratory equipment used with diagnostic and status monitoring purposes. In insurance parlance, the term is usually synonymous with assistive device, although it may include medical supplies.
Various treatment modalities that produce the desired therapeutic effect by means of change of hormone/hormones level. The treatment may include administration of hormones or hormone analogs to the patient, or decreasing the level of hormones in the body by using hormone antagonists, or hormone ablation therapy. The concept covers but not limited to: intermittent or permanent hormone suppression or ablation in treatment of hormone-dependent tumors, hormone replacement therapy of any kind, hormonal component of gender reassignment therapy, hormonal contraception, surgical and radiation castration.
(IM-yoo-no-THER-a-pee) Treatment to stimulate or restore the ability of the immune system to fight infections and other diseases. Also used to lessen side effects that may be caused by some cancer treatments.
In the process of being studied; experimental. (NCI): An active power or cause (as principle, substance, physical or biological factor, etc.) that produces a specific effect. (NCI)
use PHOTOTHERAPY, LASER THERAPY, or ULTRAVIOLET THERAPY for therapeutic radiation with visible, laser, or ultraviolet light, respectively.
A specialty in which manual or operative procedures are used in the treatment of disease, injuries, or deformities.
Hematopoietic and Lymphoid System Disorder
Any deviation from the normal structure or function of the blood or lymphatic system that is manifested by a characteristic set of symptoms and signs.
Any deviation from the normal structure or function of the cardiac system that is manifested by a characteristic set of symptoms and signs.
Congenital, familial and genetic disorders
Congenital, Familial and Genetic Disorder Class
A class of disorders that encompasses conditions resulting from a congenital, familial hereditary trait or genetic abnormality as is manifested by a characterstic set of symptoms and signs.
Any deviation from the normal structure or function of the ear or labyrinth that is manifested by a characteristic set of symptoms and signs.
Any deviation from the normal structure or function of the endocrine system that is manifested by a characteristic set of symptoms and signs.
Any deviation from the normal structure or function of the eye that is manifested by a characteristic set of symptoms and signs.
Diseases of the digestive tract (oral cavity to anus) and associated organs (salivary glands, liver, pancreas).
General disorders and administration site conditions
General Disorders and Administration Site Conditions Class
A class of disorders that encompasses conditions of a general kind that result from a disease, the treatment of disease or administration of treatment at a particular site and are manifested by a characteristic set of symptoms and signs.
Any deviation from the normal structure or function of the liver or biliary tract that is manifested by a characteristic set of symptoms and signs.
A disorder resulting from an abnormality in the immune system. -- 2003
A disorder resulting from the presence and activity of a microbial, viral, or parasitic agent. It can be transmitted by direct or indirect contact. -- 2003
Injury, poisoning and procedural complications
Injury, Poisoning and Procedural Complication Class
A class of disorders that encompasses conditions resulting from an injury, poisoning or procedure.
The act or process of a systematic and thorough examination; research, study; the process of inquiring into or following up, intended to develop facts.
A class of disorders that encompasses conditions occurring as a result of metabolic dysfunction or deviation from the normal nutritional requirements.
Musculoskeletal and connective tissue disorders
Any deviation from the normal structure or function of the musculoskeletal or connective tissue that is manifested by a characteristic set of symptoms and signs.
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
An abnormal tissue growth resulted from uncontrolled cell proliferation. Benign neoplastic cells resemble normal cells without exhibiting significant cytologic atypia, while malignant ones exhibit overt signs such as dysplastic features, atypical mitotic figures, necrosis, nuclear pleomorphism, and anaplasia. Representative examples of benign neoplasms include papillomas, cystadenomas, and lipomas; malignant neoplasms include carcinomas, sarcomas, lymphomas, and leukemias.
Any deviation from the normal structure or function of the nervous system that is manifested by a characteristic set of symptoms and signs.
Pregnancy, puerperium and perinatal conditions
Pregnancy, Puerperium and Perinatal Condition Class
A class of conditions associated with pregnancy, puerperium and perinatal status.
Any deviation from the normal structure or function of the brain and a psychiatric condition, that results in an impairment of an individual's normal cognitive, emotional, or behavioral functioning, and is caused by physiological or psychosocial factors.
Disorders of any part of the urologic system.
Reproductive system and breast disorders
Reproductive System and Breast Disorder Class
Any deviation from the normal structure or function of the reproductive system or breast that is manifested by a characteristic set of symptoms and signs.
Respiratory, thoracic and mediastinal disorders
Any deviation from the normal structure or function of the respiratory system including the thorax and mediastinum that is manifested by a characteristic set of symptoms and signs.
Any deviation from the normal structure or function of the skin or subcutaneous tissue that is manifested by a characteristic set of symptoms and signs.
A set of concepts that results from or is influenced by criteria or activities associated with the social environment of a person.
An activity that produces an effect, or that is intended to alter the course of a disease in a patient or population. This is a general term that encompasses the medical, social, behavioral, and environmnetal acts that can have preventive, therapeutic, or palliative effects.
Any deviation from the normal structure or function of the vascular system that is manifested by a characteristic set of symptoms and signs.
The absence of life or state of being dead.
One of the possible results of an adverse event outcome that indicates that the event has not improved or recuperated.
One of the possible results of an adverse event outcome that indicates that the event has improved or recuperated.
One of the possible results of an adverse event outcome where the subject recuperated but retained pathological conditions resulting from the prior disease or injury.
One of the possible results of an adverse event outcome that indicates that the event is improving.
Existing in time or space without stop or interruption.
Determination of a value is not relevant in the current context.
Requires inpatient hospitalization or prolongation of existing hospitalization
Results in persistent or significant disability/incapacity
In the medical judgment of the treating physician and/or investigator, it may jeopardize the participant or require intervention to prevent one of these outcomes
Meets criteria per protocol but does not meet other criterion (above)
Adverse Event/Serious Adverse Event CTCAE v4 NCI Standard Template
A sample questionnaire example for sdc-questionnaire profile
Must be included when this data is collected for reporting.
There are business rules to indicate situations under which this data element should be used in a CRF.
No requirement for inclusion of this element on the CRF; if the design and scientific questions posed in the study dictate the need to collect this type of data, this is the element to include on the CRF.
Were adverse events assessed during most recent period
Did event reappear after study agent was reintroduced?
Optional Serious Adverse Event Questions
The following additional elements are optional on a SAE form.