Molecular Definition Implementation Guide for Molecular Data Types
1.0.0-ballot1 - ci-build International flag

Molecular Definition Implementation Guide for Molecular Data Types, published by HL7 International / Clinical Genomics. This guide is not an authorized publication; it is the continuous build for version 1.0.0-ballot1 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/molecular-definition-data-types/ and changes regularly. See the Directory of published versions

ValueSet: Normalization Method ValueSet (Experimental)

Official URL: http://hl7.org/fhir/uv/molecular-definition-data-types/ValueSet/normalization-method Version: 1.0.0-ballot1
Standards status: Informative Draft as of 2026-03-24 Computable Name: NormalizationMethodVS

Normalization method of genomic sequence, e.g., left or right shift.

References

Logical Definition (CLD)

 

Expansion

Expansion performed internally based on codesystem Normalization Method v1.0.0-ballot1 (CodeSystem)

This value set contains 3 concepts

SystemCodeDisplay (en)DefinitionJSONXML
http://hl7.org/fhir/uv/molecular-definition-data-types/CodeSystem/normalization-method  left-shiftLeft shiftVariant coordinates normalized by shifting bases to the left, as per VCF specifications
http://hl7.org/fhir/uv/molecular-definition-data-types/CodeSystem/normalization-method  right-shiftRight shiftVariant coordinates normalized by shifting bases to the right, as per HGVS specifications
http://hl7.org/fhir/uv/molecular-definition-data-types/CodeSystem/normalization-method  fully-justifiedFully justifiedVariant coordinates normalized by full justification, as per VOCA specifications

Description of the above table(s).