{
  "resourceType" : "CodeSystem",
  "id" : "strand-orientation",
  "language" : "en",
  "text" : {
    "status" : "generated",
    "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: CodeSystem strand-orientation</b></p><a name=\"strand-orientation\"> </a><a name=\"hcstrand-orientation\"> </a><p>This case-sensitive code system <code>http://hl7.org/fhir/uv/molecular-definition-data-types/CodeSystem/strand-orientation</code> defines the following codes:</p><table class=\"codes\"><tr><td style=\"white-space:nowrap\"><b>Code</b></td><td><b>Display</b></td><td><b>Definition</b></td></tr><tr><td style=\"white-space:nowrap\">forward<a name=\"strand-orientation-forward\"> </a></td><td>Forward strand</td><td>5' to 3' for nucleotides or N-to-C for amino acids; also known as positive/plus strand. Single stranded sequences are conventionally represented in forward direction.</td></tr><tr><td style=\"white-space:nowrap\">reverse<a name=\"strand-orientation-reverse\"> </a></td><td>Reverse strand</td><td>3' to 5' orientation; also known as negative/minus strand. Applicable only to double stranded sequences.</td></tr></table></div>"
  },
  "extension" : [{
    "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-wg",
    "valueCode" : "cg"
  },
  {
    "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm",
    "valueInteger" : 0,
    "_valueInteger" : {
      "extension" : [{
        "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom",
        "valueCanonical" : "http://hl7.org/fhir/uv/molecular-definition-data-types/ImplementationGuide/hl7.fhir.uv.molecular-definition-data-types"
      }]
    }
  },
  {
    "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
    "valueCode" : "draft",
    "_valueCode" : {
      "extension" : [{
        "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom",
        "valueCanonical" : "http://hl7.org/fhir/uv/molecular-definition-data-types/ImplementationGuide/hl7.fhir.uv.molecular-definition-data-types"
      }]
    }
  }],
  "url" : "http://hl7.org/fhir/uv/molecular-definition-data-types/CodeSystem/strand-orientation",
  "version" : "1.0.0-ballot1",
  "name" : "StrandOrientation",
  "title" : "Strand Orientation",
  "status" : "draft",
  "experimental" : false,
  "date" : "2026-03-24T17:16:29+00:00",
  "publisher" : "HL7 International / Clinical Genomics",
  "contact" : [{
    "name" : "HL7 International / Clinical Genomics",
    "telecom" : [{
      "system" : "url",
      "value" : "http://www.hl7.org/Special/committees/clingenomics"
    },
    {
      "system" : "email",
      "value" : "cg@lists.HL7.org"
    }]
  }],
  "description" : "Orientation of molecular sequences, indicating directionality for nucleotides (5' to 3' or 3' to 5') or amino acids (N to C terminus)",
  "jurisdiction" : [{
    "coding" : [{
      "system" : "http://unstats.un.org/unsd/methods/m49/m49.htm",
      "code" : "001",
      "display" : "World"
    }]
  }],
  "caseSensitive" : true,
  "content" : "complete",
  "count" : 2,
  "concept" : [{
    "code" : "forward",
    "display" : "Forward strand",
    "definition" : "5' to 3' for nucleotides or N-to-C for amino acids; also known as positive/plus strand. Single stranded sequences are conventionally represented in forward direction."
  },
  {
    "code" : "reverse",
    "display" : "Reverse strand",
    "definition" : "3' to 5' orientation; also known as negative/minus strand. Applicable only to double stranded sequences."
  }]
}