{
  "resourceType" : "CodeSystem",
  "id" : "nucleotide-dna",
  "language" : "en",
  "text" : {
    "status" : "generated",
    "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: CodeSystem nucleotide-dna</b></p><a name=\"nucleotide-dna\"> </a><a name=\"hcnucleotide-dna\"> </a><p>This case-sensitive code system <code>http://hl7.org/fhir/uv/molecular-definition-data-types/CodeSystem/nucleotide-dna</code> defines the following codes:</p><table class=\"codes\"><tr><td style=\"white-space:nowrap\"><b>Code</b></td><td><b>Display</b></td><td><b>Definition</b></td></tr><tr><td style=\"white-space:nowrap\">G<a name=\"nucleotide-dna-G\"> </a></td><td>Guanine</td><td>G</td></tr><tr><td style=\"white-space:nowrap\">A<a name=\"nucleotide-dna-A\"> </a></td><td>Adenine</td><td>A</td></tr><tr><td style=\"white-space:nowrap\">T<a name=\"nucleotide-dna-T\"> </a></td><td>Thymine</td><td>T</td></tr><tr><td style=\"white-space:nowrap\">C<a name=\"nucleotide-dna-C\"> </a></td><td>Cytosine</td><td>C</td></tr><tr><td style=\"white-space:nowrap\">R<a name=\"nucleotide-dna-R\"> </a></td><td>Purine</td><td>G or A</td></tr><tr><td style=\"white-space:nowrap\">Y<a name=\"nucleotide-dna-Y\"> </a></td><td>Pyrimidine</td><td>T or C</td></tr><tr><td style=\"white-space:nowrap\">M<a name=\"nucleotide-dna-M\"> </a></td><td>Amino</td><td>A or C</td></tr><tr><td style=\"white-space:nowrap\">K<a name=\"nucleotide-dna-K\"> </a></td><td>Keto</td><td>G or T</td></tr><tr><td style=\"white-space:nowrap\">S<a name=\"nucleotide-dna-S\"> </a></td><td>Strong interaction (3 H bonds)</td><td>G or C</td></tr><tr><td style=\"white-space:nowrap\">W<a name=\"nucleotide-dna-W\"> </a></td><td>Weak interaction (2 H bonds)</td><td>A or T</td></tr><tr><td style=\"white-space:nowrap\">H<a name=\"nucleotide-dna-H\"> </a></td><td>not-G, H follows G in the alphabet</td><td>A or C or T</td></tr><tr><td style=\"white-space:nowrap\">B<a name=\"nucleotide-dna-B\"> </a></td><td>not-A, B follows A</td><td>G or T or C</td></tr><tr><td style=\"white-space:nowrap\">V<a name=\"nucleotide-dna-V\"> </a></td><td>not-T (not-U), V follows U</td><td>G or C or A</td></tr><tr><td style=\"white-space:nowrap\">D<a name=\"nucleotide-dna-D\"> </a></td><td>not-C, D follows C</td><td>G or A or T</td></tr><tr><td style=\"white-space:nowrap\">N<a name=\"nucleotide-dna-N\"> </a></td><td>Any nucleotide</td><td>G or A or T or C</td></tr></table></div>"
  },
  "extension" : [{
    "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-wg",
    "valueCode" : "cg"
  },
  {
    "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm",
    "valueInteger" : 0,
    "_valueInteger" : {
      "extension" : [{
        "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom",
        "valueCanonical" : "http://hl7.org/fhir/uv/molecular-definition-data-types/ImplementationGuide/hl7.fhir.uv.molecular-definition-data-types"
      }]
    }
  },
  {
    "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
    "valueCode" : "draft",
    "_valueCode" : {
      "extension" : [{
        "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom",
        "valueCanonical" : "http://hl7.org/fhir/uv/molecular-definition-data-types/ImplementationGuide/hl7.fhir.uv.molecular-definition-data-types"
      }]
    }
  }],
  "url" : "http://hl7.org/fhir/uv/molecular-definition-data-types/CodeSystem/nucleotide-dna",
  "version" : "1.0.0-ballot1",
  "name" : "NucleotideDNA",
  "title" : "Nucleotide DNA Symbols",
  "status" : "draft",
  "experimental" : false,
  "date" : "2026-03-24T17:16:29+00:00",
  "publisher" : "HL7 International / Clinical Genomics",
  "contact" : [{
    "name" : "HL7 International / Clinical Genomics",
    "telecom" : [{
      "system" : "url",
      "value" : "http://www.hl7.org/Special/committees/clingenomics"
    },
    {
      "system" : "email",
      "value" : "cg@lists.HL7.org"
    }]
  }],
  "description" : "Single-letter symbols for DNA residues, including unambiguous, ambiguous, and N symbols.",
  "jurisdiction" : [{
    "coding" : [{
      "system" : "http://unstats.un.org/unsd/methods/m49/m49.htm",
      "code" : "001",
      "display" : "World"
    }]
  }],
  "caseSensitive" : true,
  "content" : "complete",
  "count" : 15,
  "concept" : [{
    "code" : "G",
    "display" : "Guanine",
    "definition" : "G"
  },
  {
    "code" : "A",
    "display" : "Adenine",
    "definition" : "A"
  },
  {
    "code" : "T",
    "display" : "Thymine",
    "definition" : "T"
  },
  {
    "code" : "C",
    "display" : "Cytosine",
    "definition" : "C"
  },
  {
    "code" : "R",
    "display" : "Purine",
    "definition" : "G or A"
  },
  {
    "code" : "Y",
    "display" : "Pyrimidine",
    "definition" : "T or C"
  },
  {
    "code" : "M",
    "display" : "Amino",
    "definition" : "A or C"
  },
  {
    "code" : "K",
    "display" : "Keto",
    "definition" : "G or T"
  },
  {
    "code" : "S",
    "display" : "Strong interaction (3 H bonds)",
    "definition" : "G or C"
  },
  {
    "code" : "W",
    "display" : "Weak interaction (2 H bonds)",
    "definition" : "A or T"
  },
  {
    "code" : "H",
    "display" : "not-G, H follows G in the alphabet",
    "definition" : "A or C or T"
  },
  {
    "code" : "B",
    "display" : "not-A, B follows A",
    "definition" : "G or T or C"
  },
  {
    "code" : "V",
    "display" : "not-T (not-U), V follows U",
    "definition" : "G or C or A"
  },
  {
    "code" : "D",
    "display" : "not-C, D follows C",
    "definition" : "G or A or T"
  },
  {
    "code" : "N",
    "display" : "Any nucleotide",
    "definition" : "G or A or T or C"
  }]
}