#1

GET https://tx.fhir.org/r4/metadata HTTP/1.0
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User-Agent: fhir/publisher

200
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date:Fri, 30 Jan 2026 18:25:31 GMT
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{"resourceType" : "CapabilityStatement","id" : "FhirServer","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><h2>Local User Conformance Statement</h2><p>FHIR v4.0.1 released 20251208221453.000Z. Server version 4.0.7 built 20251208221453.000Z</p><table class=\"grid\"><tr><th>Resource Type</th><th>Profile</th><th>Read</th><th>V-Read</th><th>Search</th><th>Update</th><th>Updates</th><th>Create</th><th>Delete</th><th>History</th></tr>\n</table>\n<p>Operations</p>\n<ul>\n <li>expand: see OperationDefinition/fso-expand</li>\n <li>lookup: see OperationDefinition/fso-lookup</li>\n <li>subsumes: see OperationDefinition/fso-subsumes</li>\n <li>validate-code: see OperationDefinition/fso-validate-code</li>\n <li>batch-validate-code: see OperationDefinition/fso-batch-validate-code</li>\n <li>translate: see OperationDefinition/fso-translate</li>\n <li>closure: see OperationDefinition/fso-closure</li>\n <li>versions: see OperationDefinition/fso-versions</li>\n</ul>\n</div>"},"extension" : [{"extension" : [{"url" : "definition","valueCanonical" : "http://hl7.org/fhir/uv/tx-tests/FeatureDefinition/test-version"},{"url" : "value","valueCode" : "1.8.0"},{"extension" : [{"url" : "name","valueCode" : "mode"},{"url" : "value","valueCode" : "tx.fhir.org"}],"url" : "qualifier"}],"url" : "http://hl7.org/fhir/uv/application-feature/StructureDefinition/feature"},{"extension" : [{"url" : "definition","valueCanonical" : "http://hl7.org/fhir/uv/tx-ecosystem/FeatureDefinition/CodeSystemAsParameter"},{"url" : "value","valueBoolean" : true}],"url" : "http://hl7.org/fhir/uv/application-feature/StructureDefinition/feature"}],"url" : "http://tx.fhir.org/r4/CapabilityStatement/tx","version" : "4.0.1-4.0.7","name" : "FHIRReferenceServer","title" : "FHIR Reference Server Conformance Statement","status" : "active","date" : "2026-01-30T18:25:31.724Z","contact" : [{"telecom" : [{"system" : "other","value" : "http://healthintersections.com.au/"}]}],"description" : "Standard Conformance Statement for the open source Reference FHIR Server provided by Health Intersections","kind" : "instance","instantiates" : ["http://hl7.org/fhir/CapabilityStatement/terminology-server","http://hl7.org/fhir/CapabilityStatement/terminology-server"],"software" : {"name" : "HealthIntersections Server","version" : "4.0.7","releaseDate" : "2025-12-08T22:14:53.000Z"},"implementation" : {"description" : "FHIR Server running at http://tx.fhir.org/r4","url" : "http://tx.fhir.org/r4"},"fhirVersion" : "4.0.1","format" : ["application/fhir+xml","application/fhir+json"],"rest" : [{"mode" : "server","security" : {"cors" : true},"resource" : [{"type" : "CodeSystem","interaction" : [{"code" : "read","documentation" : "Read a code system"},{"code" : "search-type","documentation" : "Search the code systems. Not that there a few major code systems that are not available through this API (SCT, LOINC etc)"}],"operation" : [{"name" : "validate-code","definition" : "http://hl7.org/fhir/OperationDefinition/CodeSystem-validate-code"},{"name" : "lookup","definition" : "http://hl7.org/fhir/OperationDefinition/CodeSystem-lookup"}]},{"type" : "ValueSet","interaction" : [{"code" : "read","documentation" : "Read a ValueSet"},{"code" : "search-type","documentation" : "Search the value sets"}],"operation" : [{"name" : "validate-code","definition" : "http://hl7.org/fhir/OperationDefinition/ValueSet-validate-code"},{"name" : "expand","definition" : "http://hl7.org/fhir/OperationDefinition/ValueSet-expand"}]}],"interaction" : [{"code" : "transaction"}],"operation" : [{"name" : "expand","definition" : "http://hl7.org/fhir/OperationDefinition/ValueSet-expand"},{"name" : "lookup","definition" : "http://hl7.org/fhir/OperationDefinition/ValueSet-lookup"},{"name" : "subsumes","definition" : "http://hl7.org/fhir/OperationDefinition/CodeSystem-subsumes"},{"name" : "validate-code","definition" : "http://hl7.org/fhir/OperationDefinition/Resource-validate-code"},{"name" : "batch-validate-code","definition" : "http://hl7.org/fhir/OperationDefinition/Resource-batch-validate-code"},{"name" : "translate","definition" : "http://hl7.org/fhir/OperationDefinition/ConceptMap-translate"},{"name" : "closure","definition" : "http://hl7.org/fhir/OperationDefinition/ConceptMap-closure"},{"name" : "versions","definition" : "http://tx.fhir.org/r4/OperationDefinition/fso-versions"}]}]}

#2

GET https://tx.fhir.org/r4/metadata?mode=terminology HTTP/1.0
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200
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date:Fri, 30 Jan 2026 18:25:32 GMT
server:nginx
x-request-id:253-23566336

{"resourceType" : "TerminologyCapabilities","id" : "FhirServer","url" : "http://tx.fhir.org/r4/TerminologyCapabilities/tx","version" : "2.0.0","name" : "FHIRReferenceServerTerminologyCapabilities","title" : "FHIR Reference Server Terminology Capability Statement","status" : "active","date" : "2026-01-26T20:57:33.083Z","contact" : [{"telecom" : [{"system" : "other","value" : "http://healthintersections.com.au/"}]}],"description" : "Standard Terminology Capability Statement for the open source Reference FHIR Server provided by Health Intersections","kind" : "instance","codeSystem" : [{"uri" : "http://cap.org/eCP","version" : [{"code" : "4.000.001"}]},{"uri" : "http://cds-hooks.hl7.org/CodeSystem/indicator","version" : [{"code" : "4.0.1"}]},{"uri" : "http://devices.fhir.org/CodeSystem/MDC-concept-status"},{"uri" : "http://devices.fhir.org/CodeSystem/MDC-designation-use"},{"uri" : "http://dicom.nema.org/resources/ontology/DCM","version" : [{"code" : "01"}]},{"uri" : "http://dicom.nema.org/resources/ontology/DCM","version" : [{"code" : "2025.3.20250714"}]},{"uri" : "http://fdasis.nlm.nih.gov","version" : [{"code" : "2024-06-22"}]},{"uri" : "http://healthit.gov/nhin/purposeofuse","version" : [{"code" : "2.0"}]},{"uri" : "http://hl7.org/fhir/abstract-types","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/account-status","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/action-cardinality-behavior","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/action-condition-kind","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/action-grouping-behavior","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/action-participant-type","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/action-precheck-behavior","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/action-relationship-type","version" : [{"code" : "4.0.1"}]},{"uri" : 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#3

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#4

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://glstring.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://glstring.org"},{"name" : "code","valueCode" : "hla#3.23.0#HLA-B*15:01:01G+HLA-B*57:01:01G"},{"name" : "version","valueString" : "1.0"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://glstring.org|1.0#hla#3.23.0#HLA-B*15:01:01G+HLA-B*57:01:01G (\"\")]\"\r\n0 0     : 0ms  : Check \"http://glstring.org|1.0#hla#3.23.0#HLA-B*15:01:01G+HLA-B*57:01:01G\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://glstring.org|1.0\"\r\n"}]}

#5

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://glstring.org","version":"1.0","code":"hla#3.23.0#HLA-C*01:02:01G+HLA-C*03:04:01G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:26:09 GMT
last-modified:Fri, 30 Jan 2026 18:26:09 GMT
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server:nginx
x-request-id:253-23566839

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://glstring.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://glstring.org"},{"name" : "code","valueCode" : "hla#3.23.0#HLA-C*01:02:01G+HLA-C*03:04:01G"},{"name" : "version","valueString" : "1.0"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://glstring.org|1.0#hla#3.23.0#HLA-C*01:02:01G+HLA-C*03:04:01G (\"\")]\"\r\n0 0     : 0ms  : Check \"http://glstring.org|1.0#hla#3.23.0#HLA-C*01:02:01G+HLA-C*03:04:01G\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://glstring.org|1.0\"\r\n"}]}

#6

GET https://tx-nordics.fhir.org/fhir/r4/metadata HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
User-Agent: fhir/publisher

200
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content-location:https://tx-nordics.fhir.org/fhir/r4/CapabilityStatement/ec6091ce-55cb-4ce5-b5fa-03d2ce68648f
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:10 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:48fd409e-888b-4da0-af22-435c2f3277c5
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:48fd409e-888b-4da0-af22-435c2f3277c5
x-xss-protection:0

{"resourceType":"CapabilityStatement","id":"ec6091ce-55cb-4ce5-b5fa-03d2ce68648f","text":{"status":"generated","div":"<div xmlns=\"http://www.w3.org/1999/xhtml\">HAPI FHIR Server</div>"},"extension":[{"url":"http://hl7.org/fhir/uv/application-feature/StructureDefinition/feature","extension":[{"url":"definition","valueCanonical":"http://hl7.org/fhir/uv/tx-tests/FeatureDefinition/test-version"},{"url":"value","valueCode":"1.7.6"},{"url":"qualifier","extension":[{"url":"name","valueCode":"mode"},{"url":"value","valueCode":"ontoserver"},{"url":"value","valueCode":"flat"}]}]},{"url":"http://hl7.org/fhir/uv/application-feature/StructureDefinition/feature","extension":[{"url":"definition","valueCanonical":"http://hl7.org/fhir/uv/tx-ecosystem/FeatureDefinition/CodeSystemAsParameter"},{"url":"value","valueBoolean":true}]}],"url":"https://tx-nordics.fhir.org/fhir/r4/metadata","version":"6.23.0.1766071102118","name":"FHIR_Conformance_statement_for_Ontoserver","title":"FHIR Conformance statement 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#7

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date:Fri, 30 Jan 2026 18:26:10 GMT
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#8

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#9

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{"resourceType":"CodeSystem","id":"7cbe5509-3594-4900-a19d-2eceba4e74b3","meta":{"versionId":"1","lastUpdated":"2025-10-26T18:16:51.581+01:00"},"text":{"status":"generated","div":"<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: CodeSystem v3-refSeq</b></p><a name=\"v3-refSeq\"/><a name=\"hcv3-refSeq\"/><p>This case-sensitive code system <code>http://www.ncbi.nlm.nih.gov/refseq</code> defines codes, but no codes are represented here</p></div>"},"url":"http://www.ncbi.nlm.nih.gov/refseq","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.6.280"}],"version":"2.0.1","name":"RefSeq","title":"Gene Reference Sequence Collection","status":"retired","experimental":false,"date":"2021-11-09T10:00:00+10:00","publisher":"NCBI","contact":[{"name":"National Center for Biotechnology Information,National Center for Biotechnology Information"}],"description":"The Reference Sequence (RefSeq) is one of the NCBI projects, the RefSeq collection aims to provide a comprehensive, integrated, non-redundant, well-annotated set of sequences, including genomic DNA, transcripts, and proteins. ReqSeq is accessible via BLAST, Entrez, and the NCBI FTP site. Information is also available in Entrez Genomes and Entrez Gene, and for some genomes additional information is available in the Map Viewer.\r\n\r\nRefSeq entries can be used with the HL7 coded data type. For example, in the HL7 messages specified according to the HL7 V2 Clinical Genomics Fully LOINC-Qualified Genetic Variation Model, RefSeq entries can be used to as the observation values for genomic reference sequence identifiers (LOINC \\#: 48013-7).\r\n\r\nMore information may be found at: http://www.ncbi.nlm.nih.gov/RefSeq\r\n\r\nVersioning informaiton: The latest release of RefSeq was released on May 13, 2009 with the release number of 35.\r\n\r\nRefSeq generates new releases roughly every two months. The dates of the three previous releases were: Release 34, March 12, 2009 Release 33, January 20, 2009 Release 32, November 17, 2008\r\n\r\nRefSeq is a free database for the public.","caseSensitive":true,"content":"not-present"}

#10

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:12 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
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x-request-id:9c54dd10-e2a0-4385-8922-faeeecebf3e9
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#11

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA30102-0"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:763
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:26:13 GMT
last-modified:Fri, 30 Jan 2026 18:26:13 GMT
pragma:no-cache
server:nginx
x-request-id:253-23566886

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA30102-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "1-based character counting"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA30102-0 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA30102-0\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#12

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81254-5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:755
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:26:14 GMT
last-modified:Fri, 30 Jan 2026 18:26:14 GMT
pragma:no-cache
server:nginx
x-request-id:253-23566893

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81254-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic allele start-end"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81254-5 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81254-5\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#13

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:15 GMT
server:nginx
vary:Origin
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x-content-type-options:nosniff
x-correlation-id:4efa1049-f2b8-4bdd-b3ce-a5e7c5d5c622
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x-request-id:4efa1049-f2b8-4bdd-b3ce-a5e7c5d5c622
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#14

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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date:Fri, 30 Jan 2026 18:26:15 GMT
server:nginx
vary:Origin
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x-request-id:189f7130-e4f7-451b-bc8f-ee18db5a37be
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#15

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:16 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:26b029f5-b37b-495e-b46a-a341c2dc487b
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x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:26b029f5-b37b-495e-b46a-a341c2dc487b
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#16

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:16 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
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x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:0c1cc9b1-e252-4fe0-b1fa-35a7e4199d9f
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#17

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:17 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:43b1873c-bc8d-4bb1-b8bf-5c01afbc5f1c
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x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:43b1873c-bc8d-4bb1-b8bf-5c01afbc5f1c
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#18

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:17 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:ea11241f-e4ce-4c27-94b5-d72bb1b099b4
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#19

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:18 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:8f3141b0-c265-4601-9f49-89af925db4f6
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:8f3141b0-c265-4601-9f49-89af925db4f6
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#20

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:18 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:e64c7b87-3b09-4ded-956c-10c90211344b
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:e64c7b87-3b09-4ded-956c-10c90211344b
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#21

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:19 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:67ea14bf-60fe-4988-aca4-e5dce4eb593d
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:67ea14bf-60fe-4988-aca4-e5dce4eb593d
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#22

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:19 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:d9287e1e-8b94-4f9a-944c-323a253faa36
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:d9287e1e-8b94-4f9a-944c-323a253faa36
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#23

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:20 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:21317e4a-5b1e-4326-9860-429e6f1f7307
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:21317e4a-5b1e-4326-9860-429e6f1f7307
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#24

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:21 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:86fcffe6-c875-4cfe-8a2e-5ecd46b6cacf
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:86fcffe6-c875-4cfe-8a2e-5ecd46b6cacf
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#25

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:21 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:d499365b-4a91-4550-8f00-61823483dc05
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:d499365b-4a91-4550-8f00-61823483dc05
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#26

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:22 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:8bd0908a-7c82-4cc7-b67e-9348ed6ffd18
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:8bd0908a-7c82-4cc7-b67e-9348ed6ffd18
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#27

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:22 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:9fb3b972-a8f7-49e9-8a22-896696e082d1
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:9fb3b972-a8f7-49e9-8a22-896696e082d1
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#28

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:23 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:7fb3837b-463a-4ebb-8e90-2670d6fa0307
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:7fb3837b-463a-4ebb-8e90-2670d6fa0307
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#29

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:23 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:076a4b50-2bc3-4147-a047-5ee524436c9f
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:076a4b50-2bc3-4147-a047-5ee524436c9f
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#30

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:24 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:d1299dbd-3986-4ed4-a1a5-620c81baa29a
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:d1299dbd-3986-4ed4-a1a5-620c81baa29a
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#31

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:24 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:fcdb6bf7-fe92-4105-9c01-43865445c9f4
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:fcdb6bf7-fe92-4105-9c01-43865445c9f4
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#32

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:25 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:41885448-0176-469a-ad02-505df1644e3c
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:41885448-0176-469a-ad02-505df1644e3c
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#33

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:25 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:e152e05c-7394-4b27-b37e-fc3ea61b2064
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:e152e05c-7394-4b27-b37e-fc3ea61b2064
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#34

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:26 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:64b87b88-1600-46e0-955c-d5716dc68c32
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:64b87b88-1600-46e0-955c-d5716dc68c32
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#35

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:26 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:feca8f06-1290-4fab-ad32-211344318791
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:feca8f06-1290-4fab-ad32-211344318791
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#36

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:27 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:c082c943-6acf-447a-8450-b70d3bd7e8bb
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:c082c943-6acf-447a-8450-b70d3bd7e8bb
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#37

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:28 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:2d2600ef-2d93-4700-89ce-ec552d33aa83
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:2d2600ef-2d93-4700-89ce-ec552d33aa83
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#38

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:28 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:b69f528c-f3e4-411a-855e-78e7d9d6d9d8
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:b69f528c-f3e4-411a-855e-78e7d9d6d9d8
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#39

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:29 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:c7ef5fc1-e999-4ed0-a304-ff8b81029a25
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:c7ef5fc1-e999-4ed0-a304-ff8b81029a25
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#40

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:29 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:12d28b74-b488-4a02-8189-ae76ff6955a2
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:12d28b74-b488-4a02-8189-ae76ff6955a2
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#41

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:30 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:89c63e4f-38a2-4287-9735-024d49864ced
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:89c63e4f-38a2-4287-9735-024d49864ced
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#42

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:30 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:dada0caf-92e2-4641-a70a-0e6c3c05551b
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:dada0caf-92e2-4641-a70a-0e6c3c05551b
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#43

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:31 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:1f7c1f94-3261-40fd-a7d9-b3ff06cac982
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:1f7c1f94-3261-40fd-a7d9-b3ff06cac982
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#44

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:31 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:0e85713a-3a02-46c9-ad83-13eb8baace1f
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:0e85713a-3a02-46c9-ad83-13eb8baace1f
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#45

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:32 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:51724daf-dc90-43aa-b5dd-77ab6578ff51
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:51724daf-dc90-43aa-b5dd-77ab6578ff51
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#46

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:32 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:7e55ed8d-9841-4d7b-9056-da1dcfea78ac
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:7e55ed8d-9841-4d7b-9056-da1dcfea78ac
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#47

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:33 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:e2271ea1-a49c-450e-9df2-b02d066c9037
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:e2271ea1-a49c-450e-9df2-b02d066c9037
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#48

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:33 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:a190f557-1011-487b-a0d1-46f29ac1a4ec
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:a190f557-1011-487b-a0d1-46f29ac1a4ec
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#49

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:34 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:b9667696-eb59-4f2c-89cb-a68f2e682ddb
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:b9667696-eb59-4f2c-89cb-a68f2e682ddb
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#50

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:34 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:22a31e8d-87db-4df9-99cb-24a5e36d4c76
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:22a31e8d-87db-4df9-99cb-24a5e36d4c76
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#51

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:35 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:3776c784-0af2-438d-8c33-b16f18b33e9c
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:3776c784-0af2-438d-8c33-b16f18b33e9c
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#52

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:36 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:8173ea6b-1a6e-43db-aa72-ac4573c6423e
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:8173ea6b-1a6e-43db-aa72-ac4573c6423e
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#53

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:36 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:de80ee42-9a6b-462e-99c8-865f6e02328d
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:de80ee42-9a6b-462e-99c8-865f6e02328d
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#54

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:37 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:d4885cc3-f290-4564-9c58-eed3c2f515ae
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:d4885cc3-f290-4564-9c58-eed3c2f515ae
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#55

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:37 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:331b2798-a70b-48fb-a744-43fe2cd6591a
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:331b2798-a70b-48fb-a744-43fe2cd6591a
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#56

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:38 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:9e8c3f90-75da-4690-afab-baeeda5631cf
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:9e8c3f90-75da-4690-afab-baeeda5631cf
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#57

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:38 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:021155a8-cc2a-4d3e-8799-5d1317362682
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:021155a8-cc2a-4d3e-8799-5d1317362682
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#58

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:39 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:7c25369c-2280-4222-b1e5-d55ce49afb42
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:7c25369c-2280-4222-b1e5-d55ce49afb42
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#59

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:39 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:3d96bc5a-f494-4396-afa4-bc748dc31f42
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:3d96bc5a-f494-4396-afa4-bc748dc31f42
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#60

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:40 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:e59f2ea4-5e33-4184-9583-30c970a01d02
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:e59f2ea4-5e33-4184-9583-30c970a01d02
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#61

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:40 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:40e0662c-4a7b-4b80-9cb7-8ddfaeb99e45
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:40e0662c-4a7b-4b80-9cb7-8ddfaeb99e45
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#62

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:41 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:0c8b3c50-1904-42c0-9a1f-3df827c4b63f
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:0c8b3c50-1904-42c0-9a1f-3df827c4b63f
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#63

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:41 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:f3b75381-685a-416b-afb5-726216c2799d
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:f3b75381-685a-416b-afb5-726216c2799d
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#64

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:42 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:e7fa360d-f581-4c76-a02b-4c8685e9bfa4
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:e7fa360d-f581-4c76-a02b-4c8685e9bfa4
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#65

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:42 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:4609ae25-21db-4f5a-8983-c8dfdb5364f7
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:4609ae25-21db-4f5a-8983-c8dfdb5364f7
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#66

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:43 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:d737b0b6-fb58-4aa0-afde-1a5102a362a8
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:d737b0b6-fb58-4aa0-afde-1a5102a362a8
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#67

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:44 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:30dab1a7-8747-40d0-a860-7b324af8bf40
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:30dab1a7-8747-40d0-a860-7b324af8bf40
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#68

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json;charset=UTF-8
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server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:99b31d2d-ff45-4048-ba79-c49e8a7bfe0d
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:99b31d2d-ff45-4048-ba79-c49e8a7bfe0d
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#69

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:45 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:fab6dcd0-812e-4934-bc5c-56233490acb8
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:fab6dcd0-812e-4934-bc5c-56233490acb8
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#70

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:45 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:4020c29f-4816-44e4-8fa4-c6bd4d3e6ad0
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:4020c29f-4816-44e4-8fa4-c6bd4d3e6ad0
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#71

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:46 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:533eab47-1a3e-4831-bf54-c00a6f88e0ae
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:533eab47-1a3e-4831-bf54-c00a6f88e0ae
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#72

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:46 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:779cd501-cb7f-4305-a415-6c682e344ecf
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:779cd501-cb7f-4305-a415-6c682e344ecf
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#73

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:47 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:813824e6-3ac7-4087-9e27-b3b3a4f7272c
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:813824e6-3ac7-4087-9e27-b3b3a4f7272c
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#74

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:47 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:2e264a6b-a14e-4aa5-abf6-309b4f29ab5f
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:2e264a6b-a14e-4aa5-abf6-309b4f29ab5f
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#75

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:48 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:1f956f76-dada-4452-a385-3a1a175f23fd
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:1f956f76-dada-4452-a385-3a1a175f23fd
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#76

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:48 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:3aad6a76-c449-4a89-b61b-5a46b889f631
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:3aad6a76-c449-4a89-b61b-5a46b889f631
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#77

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:49 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:406ed971-0c95-4cbf-bc84-b07fb8f7ff32
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:406ed971-0c95-4cbf-bc84-b07fb8f7ff32
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#78

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json;charset=UTF-8
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server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:75038ba4-d0ed-4eb1-86e6-21282256bd81
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:75038ba4-d0ed-4eb1-86e6-21282256bd81
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#79

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:50 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:d6ff7d71-5cef-4fc6-b190-505ba720675d
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:d6ff7d71-5cef-4fc6-b190-505ba720675d
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#80

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json;charset=UTF-8
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server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:ba605b9a-b160-47c0-9d2e-e314a6a746ce
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:ba605b9a-b160-47c0-9d2e-e314a6a746ce
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#81

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:51 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:3741d1a1-6b96-4cd3-a7a4-c0b0090e443a
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:3741d1a1-6b96-4cd3-a7a4-c0b0090e443a
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#82

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:52 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:f8e61b51-0181-4183-97be-cb4d2c702e86
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:f8e61b51-0181-4183-97be-cb4d2c702e86
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#83

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json;charset=UTF-8
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server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:5d4ed7ca-e1ba-48f2-a86b-45115f6182cd
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:5d4ed7ca-e1ba-48f2-a86b-45115f6182cd
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#84

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:53 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:2a265cfa-96d4-45cf-8066-03e73476817f
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:2a265cfa-96d4-45cf-8066-03e73476817f
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#85

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:53 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:6386141c-df52-4e67-8d39-fa38ad3edea4
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:6386141c-df52-4e67-8d39-fa38ad3edea4
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#86

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"69548-6"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:757
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:26:54 GMT
last-modified:Fri, 30 Jan 2026 18:26:54 GMT
pragma:no-cache
server:nginx
x-request-id:253-23567456

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69548-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic variant assessment"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#69548-6 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#69548-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#87

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"84414-2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:745
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:26:55 GMT
last-modified:Fri, 30 Jan 2026 18:26:55 GMT
pragma:no-cache
server:nginx
x-request-id:253-23567464

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "84414-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Haplotype name"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#84414-2 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#84414-2\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#88

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","code":"*2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1496
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:26:55 GMT
last-modified:Fri, 30 Jan 2026 18:26:55 GMT
pragma:no-cache
server:nginx
x-request-id:253-23567479

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "*2"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla#*2 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ebi.ac.uk/ipd/imgt/hla#*2\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla\"\r\n"}]}

#89

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"84413-4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:752
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:26:56 GMT
last-modified:Fri, 30 Jan 2026 18:26:56 GMT
pragma:no-cache
server:nginx
x-request-id:253-23567483

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "84413-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genotype display name"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#84413-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#84413-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#90

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48018-6"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:748
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:26:57 GMT
last-modified:Fri, 30 Jan 2026 18:26:57 GMT
pragma:no-cache
server:nginx
x-request-id:253-23567515

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48018-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Gene studied [ID]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48018-6 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48018-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#91

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"51958-7"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:765
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:26:58 GMT
last-modified:Fri, 30 Jan 2026 18:26:58 GMT
pragma:no-cache
server:nginx
x-request-id:253-23567530

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51958-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Transcript reference sequence [ID]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#51958-7 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#51958-7\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#92

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_014049.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:26:59 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:2a1118b6-f12b-4ec9-bd16-b4d3359d3141
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:2a1118b6-f12b-4ec9-bd16-b4d3359d3141
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NM_014049.4"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#93

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48013-7"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:762
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:00 GMT
last-modified:Fri, 30 Jan 2026 18:27:00 GMT
pragma:no-cache
server:nginx
x-request-id:253-23567552

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48013-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic reference sequence [ID]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48013-7 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48013-7\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#94

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NG_017064.1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:27:01 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:80b6ef63-4741-4bcf-8e48-19285adfc09f
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:80b6ef63-4741-4bcf-8e48-19285adfc09f
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NG_017064.1"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#95

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81290-9"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:757
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:02 GMT
last-modified:Fri, 30 Jan 2026 18:27:02 GMT
pragma:no-cache
server:nginx
x-request-id:253-23567592

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81290-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic DNA change (gHGVS)"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81290-9 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81290-9\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#96

GET https://tx.fhir.org/r4/metadata HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
User-Agent: fhir/publisher

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:4378
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:02 GMT
pragma:no-cache
server:nginx
x-request-id:253-23567619

{"resourceType" : "CapabilityStatement","id" : "FhirServer","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><h2>Local User Conformance Statement</h2><p>FHIR v4.0.1 released 20251208221453.000Z. Server version 4.0.7 built 20251208221453.000Z</p><table class=\"grid\"><tr><th>Resource Type</th><th>Profile</th><th>Read</th><th>V-Read</th><th>Search</th><th>Update</th><th>Updates</th><th>Create</th><th>Delete</th><th>History</th></tr>\n</table>\n<p>Operations</p>\n<ul>\n <li>expand: see OperationDefinition/fso-expand</li>\n <li>lookup: see OperationDefinition/fso-lookup</li>\n <li>subsumes: see OperationDefinition/fso-subsumes</li>\n <li>validate-code: see OperationDefinition/fso-validate-code</li>\n <li>batch-validate-code: see OperationDefinition/fso-batch-validate-code</li>\n <li>translate: see OperationDefinition/fso-translate</li>\n <li>closure: see OperationDefinition/fso-closure</li>\n <li>versions: see OperationDefinition/fso-versions</li>\n</ul>\n</div>"},"extension" : [{"extension" : [{"url" : "definition","valueCanonical" : "http://hl7.org/fhir/uv/tx-tests/FeatureDefinition/test-version"},{"url" : "value","valueCode" : "1.8.0"},{"extension" : [{"url" : "name","valueCode" : "mode"},{"url" : "value","valueCode" : "tx.fhir.org"}],"url" : "qualifier"}],"url" : "http://hl7.org/fhir/uv/application-feature/StructureDefinition/feature"},{"extension" : [{"url" : "definition","valueCanonical" : "http://hl7.org/fhir/uv/tx-ecosystem/FeatureDefinition/CodeSystemAsParameter"},{"url" : "value","valueBoolean" : true}],"url" : "http://hl7.org/fhir/uv/application-feature/StructureDefinition/feature"}],"url" : "http://tx.fhir.org/r4/CapabilityStatement/tx","version" : "4.0.1-4.0.7","name" : "FHIRReferenceServer","title" : "FHIR Reference Server Conformance Statement","status" : "active","date" : "2026-01-30T18:27:02.755Z","contact" : [{"telecom" : [{"system" : "other","value" : "http://healthintersections.com.au/"}]}],"description" : "Standard Conformance Statement for the open source Reference FHIR Server provided by Health Intersections","kind" : "instance","instantiates" : ["http://hl7.org/fhir/CapabilityStatement/terminology-server","http://hl7.org/fhir/CapabilityStatement/terminology-server"],"software" : {"name" : "HealthIntersections Server","version" : "4.0.7","releaseDate" : "2025-12-08T22:14:53.000Z"},"implementation" : {"description" : "FHIR Server running at http://tx.fhir.org/r4","url" : "http://tx.fhir.org/r4"},"fhirVersion" : "4.0.1","format" : ["application/fhir+xml","application/fhir+json"],"rest" : [{"mode" : "server","security" : {"cors" : true},"resource" : [{"type" : "CodeSystem","interaction" : [{"code" : "read","documentation" : "Read a code system"},{"code" : "search-type","documentation" : "Search the code systems. Not that there a few major code systems that are not available through this API (SCT, LOINC etc)"}],"operation" : [{"name" : "validate-code","definition" : "http://hl7.org/fhir/OperationDefinition/CodeSystem-validate-code"},{"name" : "lookup","definition" : "http://hl7.org/fhir/OperationDefinition/CodeSystem-lookup"}]},{"type" : "ValueSet","interaction" : [{"code" : "read","documentation" : "Read a ValueSet"},{"code" : "search-type","documentation" : "Search the value sets"}],"operation" : [{"name" : "validate-code","definition" : "http://hl7.org/fhir/OperationDefinition/ValueSet-validate-code"},{"name" : "expand","definition" : "http://hl7.org/fhir/OperationDefinition/ValueSet-expand"}]}],"interaction" : [{"code" : "transaction"}],"operation" : [{"name" : "expand","definition" : "http://hl7.org/fhir/OperationDefinition/ValueSet-expand"},{"name" : "lookup","definition" : "http://hl7.org/fhir/OperationDefinition/ValueSet-lookup"},{"name" : "subsumes","definition" : "http://hl7.org/fhir/OperationDefinition/CodeSystem-subsumes"},{"name" : "validate-code","definition" : "http://hl7.org/fhir/OperationDefinition/Resource-validate-code"},{"name" : "batch-validate-code","definition" : "http://hl7.org/fhir/OperationDefinition/Resource-batch-validate-code"},{"name" : "translate","definition" : "http://hl7.org/fhir/OperationDefinition/ConceptMap-translate"},{"name" : "closure","definition" : "http://hl7.org/fhir/OperationDefinition/ConceptMap-closure"},{"name" : "versions","definition" : "http://tx.fhir.org/r4/OperationDefinition/fso-versions"}]}]}

#97

GET https://tx.fhir.org/r4/CodeSystem?_format=json&url=http%3A%2F%2Fvarnomen.hgvs.org HTTP/1.0
User-Agent: hapi-fhir-tooling-client
Accept: application/fhir+json; fhirVersion=4.0

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:242
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:02 GMT
pragma:no-cache
server:nginx
x-request-id:253-23567622

{"resourceType" : "Bundle","id" : "0bb96caf-35b0-4783-b2f9-594c25dc73","meta" : {"lastUpdated" : "2026-01-30T18:27:02.849Z"},"type" : "searchset","total" : 0,"link" : [{"relation" : "self","url" : "CodeSystem?&url=http://varnomen.hgvs.org"}]}

#98

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000003.11:g.128625063C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:848
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:03 GMT
last-modified:Fri, 30 Jan 2026 18:27:03 GMT
pragma:no-cache
server:nginx
x-request-id:253-23567623

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000003.11:g.128625063C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000003.11:g.128625063C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000003.11:g.128625063C>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000003.11:g.128625063C>T\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#99

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81252-9"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:755
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:04 GMT
last-modified:Fri, 30 Jan 2026 18:27:04 GMT
pragma:no-cache
server:nginx
x-request-id:253-23567629

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81252-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Discrete genetic variant"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81252-9 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81252-9\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#100

GET https://tx-nordics.fhir.org/fhir/r4/CodeSystem?_format=json&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fprojects%2FSNP HTTP/1.0
User-Agent: hapi-fhir-tooling-client
Accept: application/fhir+json; fhirVersion=4.0

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:27:04 GMT
etag:W/"1766517554440"
last-modified:Fri, 30 Jan 2026 18:27:04 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:803b9384-2c80-4882-95d8-52df98633bf4
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:803b9384-2c80-4882-95d8-52df98633bf4
x-xss-protection:0

{"resourceType":"Bundle","id":"5e2c6c2a-1ea7-3875-8f9a-5f69d31c10f3","meta":{"lastUpdated":"2026-01-30T19:27:04.954+01:00","tag":[{"system":"http://terminology.hl7.org/CodeSystem/v3-ObservationValue","code":"SUBSETTED","display":"Resource encoded in summary mode"}]},"type":"searchset","total":1,"link":[{"relation":"self","url":"https://tx-nordics.fhir.org/fhir/r4/CodeSystem?_format=json&_summary=true&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fprojects%2FSNP"}],"entry":[{"fullUrl":"https://tx-nordics.fhir.org/fhir/r4/CodeSystem/f44e2b07-9e17-49d5-a199-d7bb085ca1b4","resource":{"resourceType":"CodeSystem","id":"f44e2b07-9e17-49d5-a199-d7bb085ca1b4","meta":{"versionId":"1","lastUpdated":"2025-10-26T18:16:44.072+01:00","tag":[{"system":"http://terminology.hl7.org/CodeSystem/v3-ObservationValue","code":"SUBSETTED","display":"Resource encoded in summary mode"}]},"url":"http://www.ncbi.nlm.nih.gov/projects/SNP","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.6.284"}],"version":"2.0.1","name":"DbSNP","title":"Genetic Sequence polymorphism database","status":"retired","experimental":false,"date":"2021-11-09T10:00:00+10:00","publisher":"TBD - External Body","caseSensitive":true,"content":"not-present"}}]}

#101

GET https://tx-nordics.fhir.org/fhir/r4/CodeSystem/f44e2b07-9e17-49d5-a199-d7bb085ca1b4 HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
User-Agent: fhir/publisher

200
cache-control:no-cache
content-location:https://tx-nordics.fhir.org/fhir/r4/CodeSystem/f44e2b07-9e17-49d5-a199-d7bb085ca1b4/_history/1
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:27:05 GMT
etag:W/"1"
last-modified:Sun, 26 Oct 2025 17:16:44 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:349c172f-540c-4b01-a88e-8e6425820f25
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:349c172f-540c-4b01-a88e-8e6425820f25
x-xss-protection:0

{"resourceType":"CodeSystem","id":"f44e2b07-9e17-49d5-a199-d7bb085ca1b4","meta":{"versionId":"1","lastUpdated":"2025-10-26T18:16:44.072+01:00"},"text":{"status":"generated","div":"<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: CodeSystem v3-dbSNP</b></p><a name=\"v3-dbSNP\"/><a name=\"hcv3-dbSNP\"/><p>This case-sensitive code system <code>http://www.ncbi.nlm.nih.gov/projects/SNP</code> defines codes, but no codes are represented here</p></div>"},"url":"http://www.ncbi.nlm.nih.gov/projects/SNP","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.6.284"}],"version":"2.0.1","name":"DbSNP","title":"Genetic Sequence polymorphism database","status":"retired","experimental":false,"date":"2021-11-09T10:00:00+10:00","publisher":"TBD - External Body","description":"In collaboration with the National Human Genome Research Institute, The National Center for Biotechnology Information has established the dbSNP database to serve as a central repository for both single base nucleotide substitutions and short deletion and insertion polymorphisms.\r\n\r\nThe entries in the dbSNP database can be used with the HL7 coded data type. For example, in the HL7 messages specified according to the HL7 V2 Clinical Genomics Fully LOINC-Qualified Genetic Variation Model, dbSNP entries can be used to as the observation values for DNA sequence variation identifiers. For example, OBX|1|CWE|48004-6^DNA Sequence Variation Identifier^LN||rs55538123^^dbSNP\r\n\r\nVersioning is identified by the build id. A new build is released approximately every six months or every year. The latest build id is 130, and the dbSNP web query for built 130 was available on Apr 30, 2009.\r\n\r\ndbSNP is a database that can be used freely by the public.\r\n\r\nMore information may be fouond at: http://www.ncbi.nlm.nih.gov/projects/SNP/","caseSensitive":true,"content":"not-present"}

#102

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/projects/SNP","code":"rs368949613"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:27:06 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:173a413c-316d-4c1f-b343-df7344fb1883
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:173a413c-316d-4c1f-b343-df7344fb1883
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"rs368949613"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/projects/SNP was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/projects/SNP was not found"}]}

#103

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48004-6"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:750
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:06 GMT
last-modified:Fri, 30 Jan 2026 18:27:06 GMT
pragma:no-cache
server:nginx
x-request-id:253-23567683

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48004-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "DNA change (c.HGVS)"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48004-6 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48004-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#104

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_014049.4:c.1249C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:824
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:06 GMT
last-modified:Fri, 30 Jan 2026 18:27:06 GMT
pragma:no-cache
server:nginx
x-request-id:253-23567699

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_014049.4:c.1249C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_014049.4:c.1249C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_014049.4:c.1249C>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_014049.4:c.1249C>T\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#105

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48005-3"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:756
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:08 GMT
last-modified:Fri, 30 Jan 2026 18:27:08 GMT
pragma:no-cache
server:nginx
x-request-id:253-23567703

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48005-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Amino acid change (pHGVS)"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48005-3 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48005-3\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#106

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_054768.2:p.Arg417Cys"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:832
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:08 GMT
last-modified:Fri, 30 Jan 2026 18:27:08 GMT
pragma:no-cache
server:nginx
x-request-id:253-23567732

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_054768.2:p.Arg417Cys"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_054768.2:p.Arg417Cys"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_054768.2:p.Arg417Cys (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_054768.2:p.Arg417Cys\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#107

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48019-4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:746
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:09 GMT
last-modified:Fri, 30 Jan 2026 18:27:09 GMT
pragma:no-cache
server:nginx
x-request-id:253-23567734

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48019-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "DNA change type"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48019-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48019-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#108

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"69547-8"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:754
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:10 GMT
last-modified:Fri, 30 Jan 2026 18:27:10 GMT
pragma:no-cache
server:nginx
x-request-id:253-23567743

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69547-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic ref allele [ID]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#69547-8 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#69547-8\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#109

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"69551-0"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:754
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:11 GMT
last-modified:Fri, 30 Jan 2026 18:27:11 GMT
pragma:no-cache
server:nginx
x-request-id:253-23567773

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69551-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic alt allele [ID]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#69551-0 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#69551-0\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#110

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48001-2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:764
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:13 GMT
last-modified:Fri, 30 Jan 2026 18:27:13 GMT
pragma:no-cache
server:nginx
x-request-id:253-23567796

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48001-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Cytogenetic (chromosome) location"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48001-2 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48001-2\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#111

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48002-0"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:758
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:13 GMT
last-modified:Fri, 30 Jan 2026 18:27:13 GMT
pragma:no-cache
server:nginx
x-request-id:253-23567836

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48002-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic source class [Type]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48002-0 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48002-0\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#112

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"53034-5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:744
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:15 GMT
last-modified:Fri, 30 Jan 2026 18:27:15 GMT
pragma:no-cache
server:nginx
x-request-id:253-23567851

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "53034-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic state"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#53034-5 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#53034-5\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#113

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81258-6"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:769
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:16 GMT
last-modified:Fri, 30 Jan 2026 18:27:16 GMT
pragma:no-cache
server:nginx
x-request-id:253-23567880

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81258-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Sample variant allelic frequency [NFr]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81258-6 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81258-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#114

GET https://tx.fhir.org/r4/CodeSystem?_format=json&url=http%3A%2F%2Funitsofmeasure.org HTTP/1.0
User-Agent: hapi-fhir-tooling-client
Accept: application/fhir+json; fhirVersion=4.0

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:243
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:16 GMT
pragma:no-cache
server:nginx
x-request-id:253-23567908

{"resourceType" : "Bundle","id" : "b5b459ec-dfbb-41ec-8c5f-8be252c9e3","meta" : {"lastUpdated" : "2026-01-30T18:27:16.849Z"},"type" : "searchset","total" : 0,"link" : [{"relation" : "self","url" : "CodeSystem?&url=http://unitsofmeasure.org"}]}

#115

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://unitsofmeasure.org","code":"%"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:748
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:16 GMT
last-modified:Fri, 30 Jan 2026 18:27:16 GMT
pragma:no-cache
server:nginx
x-request-id:253-23567910

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://unitsofmeasure.org"},{"name" : "code","valueCode" : "%"},{"name" : "version","valueString" : "2.2"},{"name" : "display","valueString" : "%"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://unitsofmeasure.org#% (\"\")]\"\r\n0 0     : 0ms  : Check \"http://unitsofmeasure.org#%\"\r\n0 0     : 0ms  : Using CodeSystem \"http://unitsofmeasure.org|2.2\" (content = complete)\r\n"}]}

#116

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"82121-5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:749
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:18 GMT
last-modified:Fri, 30 Jan 2026 18:27:18 GMT
pragma:no-cache
server:nginx
x-request-id:253-23567912

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82121-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic read depth"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#82121-5 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#82121-5\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#117

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://unitsofmeasure.org","code":"1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:748
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:18 GMT
last-modified:Fri, 30 Jan 2026 18:27:18 GMT
pragma:no-cache
server:nginx
x-request-id:253-23567943

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://unitsofmeasure.org"},{"name" : "code","valueCode" : "1"},{"name" : "version","valueString" : "2.2"},{"name" : "display","valueString" : "1"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://unitsofmeasure.org#1 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://unitsofmeasure.org#1\"\r\n0 0     : 0ms  : Using CodeSystem \"http://unitsofmeasure.org|2.2\" (content = complete)\r\n"}]}

#118

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"82155-3"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:769
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:20 GMT
last-modified:Fri, 30 Jan 2026 18:27:20 GMT
pragma:no-cache
server:nginx
x-request-id:253-23567944

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82155-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic structural variant copy number"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#82155-3 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#82155-3\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#119

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81301-4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:769
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:21 GMT
last-modified:Fri, 30 Jan 2026 18:27:21 GMT
pragma:no-cache
server:nginx
x-request-id:253-23567970

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81301-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Structural variant outer start and end"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81301-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81301-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#120

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81302-2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:769
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:23 GMT
last-modified:Fri, 30 Jan 2026 18:27:23 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568000

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81302-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Structural variant inner start and end"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81302-2 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81302-2\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#121

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"53037-8"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:776
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:24 GMT
last-modified:Fri, 30 Jan 2026 18:27:24 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568026

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "53037-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic variation clinical significance [Imp]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#53037-8 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#53037-8\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#122

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81259-4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:751
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:26 GMT
last-modified:Fri, 30 Jan 2026 18:27:26 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568050

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81259-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Associated phenotype"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n15 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n15 0    : 0ms  : Prepare include: \"()\"\r\n15 0    : 0ms  : Validate \"[http://loinc.org#81259-4 (\"\")]\"\r\n15 0    : 0ms  : Check \"http://loinc.org#81259-4\"\r\n15 0    : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#123

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_000106.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:27:26 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:59c3a930-24ff-40c7-93e4-89c4e2f3572d
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:59c3a930-24ff-40c7-93e4-89c4e2f3572d
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NM_000106.5"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#124

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000106.5:c.886C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:820
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:26 GMT
last-modified:Fri, 30 Jan 2026 18:27:26 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568094

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000106.5:c.886C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000106.5:c.886C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_000106.5:c.886C>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_000106.5:c.886C>T\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#125

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_000097.3:p.Arg296Cys"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:832
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:27 GMT
last-modified:Fri, 30 Jan 2026 18:27:27 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568102

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_000097.3:p.Arg296Cys"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_000097.3:p.Arg296Cys"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_000097.3:p.Arg296Cys (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_000097.3:p.Arg296Cys\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#126

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_000106.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:27:27 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:bf41295b-8d81-4ec5-a45a-0b788d7a55bb
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:bf41295b-8d81-4ec5-a45a-0b788d7a55bb
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NM_000106.5"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#127

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000106.5:c.1457G>C"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:824
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:27 GMT
last-modified:Fri, 30 Jan 2026 18:27:27 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568114

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000106.5:c.1457G>C"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000106.5:c.1457G>C"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_000106.5:c.1457G>C (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_000106.5:c.1457G>C\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#128

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","code":"*2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1496
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:27 GMT
last-modified:Fri, 30 Jan 2026 18:27:27 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568118

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "*2"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla#*2 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ebi.ac.uk/ipd/imgt/hla#*2\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla\"\r\n"}]}

#129

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"51963-7"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:755
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:29 GMT
last-modified:Fri, 30 Jan 2026 18:27:29 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568119

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51963-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Medication assessed [ID]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#51963-7 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#51963-7\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#130

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"51969-4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:754
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:30 GMT
last-modified:Fri, 30 Jan 2026 18:27:30 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568143

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51969-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic analysis report"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#51969-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#51969-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#131

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","code":"*2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1496
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:30 GMT
last-modified:Fri, 30 Jan 2026 18:27:30 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568165

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "*2"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla#*2 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ebi.ac.uk/ipd/imgt/hla#*2\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla\"\r\n"}]}

#132

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_014049.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:27:31 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:e318d333-c9c7-4d4a-ba92-b99f180b55ce
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:e318d333-c9c7-4d4a-ba92-b99f180b55ce
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NM_014049.4"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#133

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NG_017064.1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:27:31 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:f8f54093-707a-4959-b141-349cbb425b3b
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:f8f54093-707a-4959-b141-349cbb425b3b
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NG_017064.1"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#134

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/projects/SNP","version":"137","code":"rs368949613"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:27:32 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:7e26354a-3da7-40c9-9818-ce594fe30994
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:7e26354a-3da7-40c9-9818-ce594fe30994
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"rs368949613"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name":"version","valueString":"137"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/projects/SNP|137 was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' version '137' could not be found, so the code cannot be validated. Valid versions: [2.0.1]"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/projects/SNP|137"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' version '137' could not be found, so the code cannot be validated. Valid versions: [2.0.1]; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/projects/SNP|137 was not found"}]}

#135

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81299-0"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:773
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:33 GMT
last-modified:Fri, 30 Jan 2026 18:27:33 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568193

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81299-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Structural variant reported arrCGH [Ratio]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81299-0 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81299-0\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#136

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81300-6"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:758
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:35 GMT
last-modified:Fri, 30 Jan 2026 18:27:35 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568210

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81300-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Structural variant [Length]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81300-6 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81300-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#137

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_000106.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:27:35 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:4bc88460-09c6-4ee7-8d67-5ee3f5496e0b
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:4bc88460-09c6-4ee7-8d67-5ee3f5496e0b
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NM_000106.5"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#138

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_000106.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:27:36 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:fdde8a75-aa9d-4990-b8ff-7aa4249845a0
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:fdde8a75-aa9d-4990-b8ff-7aa4249845a0
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NM_000106.5"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#139

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","code":"*2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1496
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:36 GMT
last-modified:Fri, 30 Jan 2026 18:27:36 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568255

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "*2"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla#*2 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ebi.ac.uk/ipd/imgt/hla#*2\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla\"\r\n"}]}

#140

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://unitsofmeasure.org","code":"1/1000000"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:780
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:36 GMT
last-modified:Fri, 30 Jan 2026 18:27:36 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568256

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://unitsofmeasure.org"},{"name" : "code","valueCode" : "1/1000000"},{"name" : "version","valueString" : "2.2"},{"name" : "display","valueString" : "1/1000000"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://unitsofmeasure.org#1/1000000 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://unitsofmeasure.org#1/1000000\"\r\n0 0     : 0ms  : Using CodeSystem \"http://unitsofmeasure.org|2.2\" (content = complete)\r\n"}]}

#141

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://hl7.org/fhir/sid/icd-10-cm","code":"C16.0"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:854
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:36 GMT
last-modified:Fri, 30 Jan 2026 18:27:36 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568261

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://hl7.org/fhir/sid/icd-10-cm"},{"name" : "code","valueCode" : "C16.0"},{"name" : "version","valueString" : "2024"},{"name" : "display","valueString" : "Malignant neoplasm of cardia"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://hl7.org/fhir/sid/icd-10-cm#C16.0 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://hl7.org/fhir/sid/icd-10-cm#C16.0\"\r\n0 0     : 0ms  : Using CodeSystem \"http://hl7.org/fhir/sid/icd-10-cm|2024 (from fhir.tx.support.r4#0.32.0)\" (content = complete)\r\n"}]}

#142

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000077.4:c.9_32del"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:824
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:36 GMT
last-modified:Fri, 30 Jan 2026 18:27:36 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568265

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000077.4:c.9_32del"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000077.4:c.9_32del"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_000077.4:c.9_32del (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_000077.4:c.9_32del\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#143

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_000068.1:p.Ala4_Pro11del"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:848
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:36 GMT
last-modified:Fri, 30 Jan 2026 18:27:36 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568269

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_000068.1:p.Ala4_Pro11del"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_000068.1:p.Ala4_Pro11del"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_000068.1:p.Ala4_Pro11del (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_000068.1:p.Ala4_Pro11del\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#144

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_004260.4:c.2086C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:824
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:37 GMT
last-modified:Fri, 30 Jan 2026 18:27:37 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568273

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_004260.4:c.2086C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_004260.4:c.2086C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_004260.4:c.2086C>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_004260.4:c.2086C>T\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#145

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_004251.4:p.Arg696Cys"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:832
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:37 GMT
last-modified:Fri, 30 Jan 2026 18:27:37 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568278

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_004251.4:p.Arg696Cys"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_004251.4:p.Arg696Cys"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_004251.4:p.Arg696Cys (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_004251.4:p.Arg696Cys\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#146

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000540.3:c.4964G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:824
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:37 GMT
last-modified:Fri, 30 Jan 2026 18:27:37 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568280

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000540.3:c.4964G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000540.3:c.4964G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_000540.3:c.4964G>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_000540.3:c.4964G>A\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#147

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_000531.2:p.Arg1655Leu"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:836
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:37 GMT
last-modified:Fri, 30 Jan 2026 18:27:37 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568282

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_000531.2:p.Arg1655Leu"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_000531.2:p.Arg1655Leu"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_000531.2:p.Arg1655Leu (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_000531.2:p.Arg1655Leu\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#148

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_014363.5:c.12118G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:828
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:37 GMT
last-modified:Fri, 30 Jan 2026 18:27:37 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568287

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_014363.5:c.12118G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_014363.5:c.12118G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_014363.5:c.12118G>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_014363.5:c.12118G>A\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#149

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_004787.3:c.1290C>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:824
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:37 GMT
last-modified:Fri, 30 Jan 2026 18:27:37 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568289

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_004787.3:c.1290C>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_004787.3:c.1290C>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_004787.3:c.1290C>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_004787.3:c.1290C>A\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#150

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_003072.5:c.2372C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:824
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:38 GMT
last-modified:Fri, 30 Jan 2026 18:27:38 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568293

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_003072.5:c.2372C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_003072.5:c.2372C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_003072.5:c.2372C>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_003072.5:c.2372C>T\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#151

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_003063.2:p.Ala791Val"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:832
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:38 GMT
last-modified:Fri, 30 Jan 2026 18:27:38 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568296

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_003063.2:p.Ala791Val"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_003063.2:p.Ala791Val"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_003063.2:p.Ala791Val (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_003063.2:p.Ala791Val\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#152

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"93044-6"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:748
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:39 GMT
last-modified:Fri, 30 Jan 2026 18:27:39 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568300

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "93044-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Level of evidence"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#93044-6 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#93044-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#153

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/projects/SNP","code":"rs12345"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:27:40 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:565f5445-681a-4340-bde4-7a1b1ab16176
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:565f5445-681a-4340-bde4-7a1b1ab16176
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"rs12345"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/projects/SNP was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/projects/SNP was not found"}]}

#154

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NG_007726.3"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:27:40 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:94054bcb-b1cc-4e66-912c-e0ff399345f4
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:94054bcb-b1cc-4e66-912c-e0ff399345f4
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NG_007726.3"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#155

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/projects/SNP","code":"rs233455"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:27:41 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:c45ba5c2-ad74-4bce-8e23-938cf6ce9327
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:c45ba5c2-ad74-4bce-8e23-938cf6ce9327
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"rs233455"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/projects/SNP was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/projects/SNP was not found"}]}

#156

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NG-007726.3"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:27:41 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:3af3dcab-0f4b-4d6e-b5c5-072f7e245709
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:3af3dcab-0f4b-4d6e-b5c5-072f7e245709
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NG-007726.3"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#157

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NG-007726.3"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:27:42 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:5293e582-2d42-42d7-9b4a-a82b38505ffb
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:5293e582-2d42-42d7-9b4a-a82b38505ffb
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NG-007726.3"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#158

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:27:42 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:5aa4cf85-8b46-4dcc-88e0-6f5852d6e580
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:5aa4cf85-8b46-4dcc-88e0-6f5852d6e580
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#159

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:27:43 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:49eed4d9-929e-465a-a509-e65af194ea4f
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:49eed4d9-929e-465a-a509-e65af194ea4f
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#160

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://glstring.org","version":"1.0","code":"hla#3.31.0#HLA-A*03:01:01:01+HLA-A*30:01:01"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
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connection:keep-alive
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date:Fri, 30 Jan 2026 18:27:43 GMT
last-modified:Fri, 30 Jan 2026 18:27:43 GMT
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://glstring.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://glstring.org"},{"name" : "code","valueCode" : "hla#3.31.0#HLA-A*03:01:01:01+HLA-A*30:01:01"},{"name" : "version","valueString" : "1.0"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n15 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n15 0    : 0ms  : Prepare include: \"()\"\r\n15 0    : 0ms  : Validate \"[http://glstring.org|1.0#hla#3.31.0#HLA-A*03:01:01:01+HLA-A*30:01:01 (\"\")]\"\r\n15 0    : 0ms  : Check \"http://glstring.org|1.0#hla#3.31.0#HLA-A*03:01:01:01+HLA-A*30:01:01\"\r\n15 0    : 0ms  : Didn't find CodeSystem \"http://glstring.org|1.0\"\r\n"}]}

#161

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","version":"3.31.0","code":"HLA-A*03:01:01:01"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1741
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:44 GMT
last-modified:Fri, 30 Jan 2026 18:27:44 GMT
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server:nginx
x-request-id:253-23568386

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "HLA-A*03:01:01:01"},{"name" : "version","valueString" : "3.31.0"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.31.0' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.31.0' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla|3.31.0#HLA-A*03:01:01:01 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ebi.ac.uk/ipd/imgt/hla|3.31.0#HLA-A*03:01:01:01\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla|3.31.0\"\r\n"}]}

#162

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_001184.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:27:44 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:b60d638f-5984-4e9c-b043-9d0f8c00659a
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:b60d638f-5984-4e9c-b043-9d0f8c00659a
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NM_001184.4"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#163

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_001184.4:c.2878_2879insAGTAA"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:864
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:44 GMT
last-modified:Fri, 30 Jan 2026 18:27:44 GMT
pragma:no-cache
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x-request-id:253-23568399

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_001184.4:c.2878_2879insAGTAA"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_001184.4:c.2878_2879insAGTAA"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_001184.4:c.2878_2879insAGTAA (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_001184.4:c.2878_2879insAGTAA\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#164

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48000-4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:802
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:46 GMT
last-modified:Fri, 30 Jan 2026 18:27:46 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568402

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48000-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Chromosome [Identifier] in Blood or Tissue by Molecular genetics method"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48000-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48000-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#165

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000003.11"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:27:46 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:323ecae9-a0ef-4f4a-aef7-59094cbf132b
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:323ecae9-a0ef-4f4a-aef7-59094cbf132b
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000003.11"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#166

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000003.11:g.142269071_142269072insTTACT"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:908
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date:Fri, 30 Jan 2026 18:27:47 GMT
last-modified:Fri, 30 Jan 2026 18:27:47 GMT
pragma:no-cache
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x-request-id:253-23568432

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000003.11:g.142269071_142269072insTTACT"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000003.11:g.142269071_142269072insTTACT"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000003.11:g.142269071_142269072insTTACT (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000003.11:g.142269071_142269072insTTACT\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#167

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_005219.2:p.Leu858Arg"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:832
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:47 GMT
last-modified:Fri, 30 Jan 2026 18:27:47 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568435

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_005219.2:p.Leu858Arg"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_005219.2:p.Leu858Arg"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_005219.2:p.Leu858Arg (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_005219.2:p.Leu858Arg\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#168

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_005228.4:c.2573T>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:824
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:47 GMT
last-modified:Fri, 30 Jan 2026 18:27:47 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568438

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_005228.4:c.2573T>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_005228.4:c.2573T>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_005228.4:c.2573T>G (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_005228.4:c.2573T>G\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#169

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000007.13:g.55259515T>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
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content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:47 GMT
last-modified:Fri, 30 Jan 2026 18:27:47 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568441

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000007.13:g.55259515T>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000007.13:g.55259515T>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000007.13:g.55259515T>G (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000007.13:g.55259515T>G\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#170

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000022.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:27:47 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:ae633cea-c703-4c37-90a0-20005e6f26a0
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:ae633cea-c703-4c37-90a0-20005e6f26a0
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000022.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#171

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"92822-6"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:763
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:49 GMT
last-modified:Fri, 30 Jan 2026 18:27:49 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568455

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "92822-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic coordinate system [Type]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#92822-6 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#92822-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#172

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"94186-4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:772
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:51 GMT
last-modified:Fri, 30 Jan 2026 18:27:51 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568476

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "94186-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Origin of germline genetic variant [Type]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#94186-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#94186-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#173

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"82309-6"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:761
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:52 GMT
last-modified:Fri, 30 Jan 2026 18:27:52 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568503

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82309-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Basis for allelic phase [Type]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#82309-6 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#82309-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#174

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000001.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:27:52 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:0e7d06cb-bc76-4444-ba5e-9dd56c77c5b3
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x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:0e7d06cb-bc76-4444-ba5e-9dd56c77c5b3
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000001.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#175

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000001.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:27:53 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:418705e3-dba1-47d1-9219-b694618035be
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:418705e3-dba1-47d1-9219-b694618035be
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000001.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#176

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000022.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:27:53 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:651f701d-6232-4877-bc0d-b36cba29a87f
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x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:651f701d-6232-4877-bc0d-b36cba29a87f
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000022.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#177

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000001.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:27:54 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:3377aab7-963f-4a39-8169-ad856800f130
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:3377aab7-963f-4a39-8169-ad856800f130
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000001.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#178

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000001.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:27:55 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:85e6f985-fc2a-468d-9364-66634742ee1c
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:85e6f985-fc2a-468d-9364-66634742ee1c
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000001.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#179

GET https://tx-nordics.fhir.org/fhir/r4/CodeSystem?_format=json&url=https%3A%2F%2Fiscn.karger.com HTTP/1.0
User-Agent: hapi-fhir-tooling-client
Accept: application/fhir+json; fhirVersion=4.0

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:27:55 GMT
etag:W/"1768325767593"
last-modified:Fri, 30 Jan 2026 18:27:55 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:3ad9de50-254a-4a58-bb2a-0f672b6138e4
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
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#180

GET https://tx-nordics.fhir.org/fhir/r4/CodeSystem/2c8cbd02-f8f2-41c1-8734-c2b5756981f3 HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
User-Agent: fhir/publisher

200
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date:Fri, 30 Jan 2026 18:27:56 GMT
etag:W/"1"
last-modified:Sun, 26 Oct 2025 17:16:32 GMT
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{"resourceType":"CodeSystem","id":"2c8cbd02-f8f2-41c1-8734-c2b5756981f3","meta":{"versionId":"1","lastUpdated":"2025-10-26T18:16:32.080+01:00"},"text":{"status":"generated","div":"<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: CodeSystem ISCN</b></p><a name=\"ISCN\"/><a name=\"hcISCN\"/><p>This case-sensitive code system <code>https://iscn.karger.com</code> defines codes, but no codes are represented here</p></div>"},"url":"https://iscn.karger.com","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.6.299"}],"version":"1.0.1","name":"ISCN","title":"International System for Human Cytogenomic Nomenclature (ISCN)","status":"active","experimental":false,"date":"2022-06-07T00:00:00-00:00","publisher":"S. Karger AG","contact":[{"name":"S. Karger AG; P.O Box, CH-4009 Basel (Switzerland) Allschwilerstrasse 10, CH-4055 Basel","telecom":[{"system":"url","value":"https://www.karger.com/"},{"system":"email","value":"info@signaturegenomics.com"},{"system":"phone","value":"+41 61 306 11 11"}]}],"description":"The International System for Human Cytogenetic Nomenclature (ISCN) was created by the International Standing committee on Human Cytogenetic Nomenclature to represent the outcome of cytogenetic tests. ISCN specifies the nomenclature to describe karyotypes, chromosome abnormalities, in situ hybridization, etc. ISCN provides a list of symbols and abbreviated terms in adjunction with a set of rules, which can be used in the description of chromosomes and chromosome abnormalities, such as p for short arm of chromosome, q for long arm of chromosome, cen for centromere, del for deletion, ish for in situ hybridization, and plus sign (+) for gain, etc.\r\n\r\nA LOINC code is created to represent \"chromosome analysis results in ISCN expression\". In HL7 v2 messages, this LOINC code is used in OBX-3 with a coded result (CWE data type) that will be sent in OBX-5. The value of the coded result is an ISCN expression, and ISCN will be the code system for the coded result.","copyright":"The content on the Website including but not limited to the content of ISCN 2020 in whole or in parts, the title, the logo, graphic designs or adverts are the intellectual property of S. Karger AG (Basel) or published with permission from the legal copyright owner. All rights are reserved. Unless otherwise noted, no part of the content on the Website may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from Karger.\r\n\r\nFor further information or permission requests please see the explanations under Rights and Permissions (https://www.karger.com/Services/RightsPermissions).","caseSensitive":true,"content":"not-present"}

#181

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"https://iscn.karger.com","code":"46,XX,t(9;22)(q34;q4)"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"46,XX,t(9;22)(q34;q4)"},{"name":"system","valueUri":"https://iscn.karger.com"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system https://iscn.karger.com was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'https://iscn.karger.com' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"https://iscn.karger.com"},{"name":"message","valueString":"A definition for CodeSystem 'https://iscn.karger.com' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system https://iscn.karger.com was not found"}]}

#182

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"https://iscn.karger.com","code":"46,XX"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"46,XX"},{"name":"system","valueUri":"https://iscn.karger.com"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system https://iscn.karger.com was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'https://iscn.karger.com' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"https://iscn.karger.com"},{"name":"message","valueString":"A definition for CodeSystem 'https://iscn.karger.com' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system https://iscn.karger.com was not found"}]}

#183

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_006885.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NM_006885.4"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#184

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_060087.3:p.A1931T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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cache-control:public, max-age=600
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content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:58 GMT
last-modified:Fri, 30 Jan 2026 18:27:58 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568602

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_060087.3:p.A1931T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_060087.3:p.A1931T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_060087.3:p.A1931T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_060087.3:p.A1931T\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#185

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
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{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_017617.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NM_017617.5"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#186

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_017617.5:c.5791G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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last-modified:Fri, 30 Jan 2026 18:27:58 GMT
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_017617.5:c.5791G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_017617.5:c.5791G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_017617.5:c.5791G>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_017617.5:c.5791G>A\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#187

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
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{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000009.11"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000009.11"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#188

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000009.11:g.139395147C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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date:Fri, 30 Jan 2026 18:27:59 GMT
last-modified:Fri, 30 Jan 2026 18:27:59 GMT
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server:nginx
x-request-id:253-23568625

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000009.11:g.139395147C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000009.11:g.139395147C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000009.11:g.139395147C>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000009.11:g.139395147C>T\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#189

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_002519.2:p.Trp243Ter"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:832
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:59 GMT
last-modified:Fri, 30 Jan 2026 18:27:59 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568629

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_002519.2:p.Trp243Ter"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_002519.2:p.Trp243Ter"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_002519.2:p.Trp243Ter (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_002519.2:p.Trp243Ter\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#190

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_002528.7:c.728G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:820
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:59 GMT
last-modified:Fri, 30 Jan 2026 18:27:59 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568637

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_002528.7:c.728G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_002528.7:c.728G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_002528.7:c.728G>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_002528.7:c.728G>A\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#191

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000016.10:g.2040196C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:840
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:27:59 GMT
last-modified:Fri, 30 Jan 2026 18:27:59 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568643

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000016.10:g.2040196C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000016.10:g.2040196C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000016.10:g.2040196C>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000016.10:g.2040196C>T\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#192

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000010.10:g.96540410G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:844
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:28:00 GMT
last-modified:Fri, 30 Jan 2026 18:28:00 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568645

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000010.10:g.96540410G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000010.10:g.96540410G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000010.10:g.96540410G>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000010.10:g.96540410G>A\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#193

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000016.9:g.31096368G>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:840
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:28:00 GMT
last-modified:Fri, 30 Jan 2026 18:28:00 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568649

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000016.9:g.31096368G>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000016.9:g.31096368G>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000016.9:g.31096368G>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000016.9:g.31096368G>T\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#194

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000044.6:c.7G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:812
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:28:00 GMT
last-modified:Fri, 30 Jan 2026 18:28:00 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568651

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000044.6:c.7G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000044.6:c.7G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_000044.6:c.7G>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_000044.6:c.7G>A\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#195

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_006594.3:p.S1178*"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:820
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:28:00 GMT
last-modified:Fri, 30 Jan 2026 18:28:00 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568655

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_006594.3:p.S1178*"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_006594.3:p.S1178*"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_006594.3:p.S1178* (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_006594.3:p.S1178*\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#196

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_006603.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:28:01 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:d5bbce54-9b3f-4778-9d07-e81f1211cff0
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:d5bbce54-9b3f-4778-9d07-e81f1211cff0
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NM_006603.5"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#197

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_006603.5:c.3530_3531insGTGACTATTAATAT"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:900
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:28:01 GMT
last-modified:Fri, 30 Jan 2026 18:28:01 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568669

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_006603.5:c.3530_3531insGTGACTATTAATAT"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_006603.5:c.3530_3531insGTGACTATTAATAT"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_006603.5:c.3530_3531insGTGACTATTAATAT (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_006603.5:c.3530_3531insGTGACTATTAATAT\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#198

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000023.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:28:01 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:13911591-7914-4dbf-91cf-697c05faafe9
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:13911591-7914-4dbf-91cf-697c05faafe9
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000023.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#199

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000023.10:g.123227930_123227931insGTGACTATTAATAT"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:944
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:28:02 GMT
last-modified:Fri, 30 Jan 2026 18:28:02 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568682

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000023.10:g.123227930_123227931insGTGACTATTAATAT"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000023.10:g.123227930_123227931insGTGACTATTAATAT"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000023.10:g.123227930_123227931insGTGACTATTAATAT (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000023.10:g.123227930_123227931insGTGACTATTAATAT\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#200

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"82120-7"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:744
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:28:03 GMT
last-modified:Fri, 30 Jan 2026 18:28:03 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568687

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82120-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic phase"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#82120-7 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#82120-7\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#201

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000017.11"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:28:03 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:a374b18e-bce6-409a-bea8-456c65de8185
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:a374b18e-bce6-409a-bea8-456c65de8185
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000017.11"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#202

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA30100-4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:762
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:28:05 GMT
last-modified:Fri, 30 Jan 2026 18:28:05 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568722

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA30100-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "0-based interval counting"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA30100-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA30100-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#203

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:28:06 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:b1ffb7e8-2876-456a-8bb6-8a24ec92dec2
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:b1ffb7e8-2876-456a-8bb6-8a24ec92dec2
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#204

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_008816.3:p.G585S"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:816
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:28:06 GMT
last-modified:Fri, 30 Jan 2026 18:28:06 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568752

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_008816.3:p.G585S"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_008816.3:p.G585S"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_008816.3:p.G585S (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_008816.3:p.G585S\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#205

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_006885.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:28:06 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:2dddcf54-6298-403f-9cb1-8c28773e55cc
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:2dddcf54-6298-403f-9cb1-8c28773e55cc
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NM_006885.4"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#206

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_006885.4:c.1753G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:824
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:28:07 GMT
last-modified:Fri, 30 Jan 2026 18:28:07 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568767

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_006885.4:c.1753G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_006885.4:c.1753G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_006885.4:c.1753G>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_006885.4:c.1753G>A\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#207

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000016.9"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:28:07 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:568a8b3b-4cdd-49fc-859a-8c0cb7433c4f
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:568a8b3b-4cdd-49fc-859a-8c0cb7433c4f
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000016.9"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#208

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000016.9:g.72992292C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:840
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:28:07 GMT
last-modified:Fri, 30 Jan 2026 18:28:07 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568780

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000016.9:g.72992292C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000016.9:g.72992292C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000016.9:g.72992292C>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000016.9:g.72992292C>T\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#209

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000005.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:28:08 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:209468cd-fe24-4fee-8c26-cc504767c65d
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:209468cd-fe24-4fee-8c26-cc504767c65d
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000005.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#210

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000005.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:28:08 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:ff91f6b4-2593-49a9-a3fc-92d51aa6926a
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x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:ff91f6b4-2593-49a9-a3fc-92d51aa6926a
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000005.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#211

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000001.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:28:09 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:45a34a49-2a17-40ab-8c1a-115c47090d4c
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:45a34a49-2a17-40ab-8c1a-115c47090d4c
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000001.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#212

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://example.org/hgsc.bcm.edu/lab-test-codes/","code":"emerge-seq-ngs-pnl"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1642
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:28:09 GMT
last-modified:Fri, 30 Jan 2026 18:28:09 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568813

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://example.org/hgsc.bcm.edu/lab-test-codes/"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://example.org/hgsc.bcm.edu/lab-test-codes/"},{"name" : "code","valueCode" : "emerge-seq-ngs-pnl"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://example.org/hgsc.bcm.edu/lab-test-codes/' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://example.org/hgsc.bcm.edu/lab-test-codes/' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://example.org/hgsc.bcm.edu/lab-test-codes/#emerge-seq-ngs-pnl (\"\")]\"\r\n0 0     : 0ms  : Check \"http://example.org/hgsc.bcm.edu/lab-test-codes/#emerge-seq-ngs-pnl\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://example.org/hgsc.bcm.edu/lab-test-codes/\"\r\n"}]}

#213

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://example.org/hgsc.bcm.edu/lab-test-codes/","code":"emerge-seq-ngs-pnl"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1642
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:28:09 GMT
last-modified:Fri, 30 Jan 2026 18:28:09 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568818

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://example.org/hgsc.bcm.edu/lab-test-codes/"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://example.org/hgsc.bcm.edu/lab-test-codes/"},{"name" : "code","valueCode" : "emerge-seq-ngs-pnl"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://example.org/hgsc.bcm.edu/lab-test-codes/' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://example.org/hgsc.bcm.edu/lab-test-codes/' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://example.org/hgsc.bcm.edu/lab-test-codes/#emerge-seq-ngs-pnl (\"\")]\"\r\n0 0     : 0ms  : Check \"http://example.org/hgsc.bcm.edu/lab-test-codes/#emerge-seq-ngs-pnl\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://example.org/hgsc.bcm.edu/lab-test-codes/\"\r\n"}]}

#214

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA26421-0"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:768
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:28:12 GMT
last-modified:Fri, 30 Jan 2026 18:28:12 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568850

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26421-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Consider alternative medication"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA26421-0 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA26421-0\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#215

GET https://tx-nordics.fhir.org/fhir/r4/CodeSystem?_format=json&url=http%3A%2F%2Fhuman-phenotype-ontology.org HTTP/1.0
User-Agent: hapi-fhir-tooling-client
Accept: application/fhir+json; fhirVersion=4.0

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:28:13 GMT
etag:W/"1766358591982"
last-modified:Fri, 30 Jan 2026 18:28:13 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:71ee8d82-3fb5-4d08-9db4-d21a72fb2bf0
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:71ee8d82-3fb5-4d08-9db4-d21a72fb2bf0
x-xss-protection:0

{"resourceType":"Bundle","id":"4d66ff29-64b7-3a47-b763-8ba8bfced62c","meta":{"lastUpdated":"2026-01-30T19:28:13.368+01:00","tag":[{"system":"http://terminology.hl7.org/CodeSystem/v3-ObservationValue","code":"SUBSETTED","display":"Resource encoded in summary mode"}]},"type":"searchset","total":1,"link":[{"relation":"self","url":"https://tx-nordics.fhir.org/fhir/r4/CodeSystem?_format=json&_summary=true&url=http%3A%2F%2Fhuman-phenotype-ontology.org"}],"entry":[{"fullUrl":"https://tx-nordics.fhir.org/fhir/r4/CodeSystem/d2cd8840-a2e8-439b-ba71-cc6c09083a0a","resource":{"resourceType":"CodeSystem","id":"d2cd8840-a2e8-439b-ba71-cc6c09083a0a","meta":{"versionId":"1","lastUpdated":"2025-10-26T18:16:30.924+01:00","tag":[{"system":"http://terminology.hl7.org/CodeSystem/v3-ObservationValue","code":"SUBSETTED","display":"Resource encoded in summary mode"}]},"url":"http://human-phenotype-ontology.org","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.6.339"}],"version":"1.0.0","name":"HPO","title":"Human Phenotype Ontology","status":"active","experimental":false,"date":"2022-06-02T00:00:00-00:00","contact":[{"name":"Peter Robinson or Melissa Haendel, The Monarch Initiative","telecom":[{"system":"url","value":"http://www.human-phenotype-ontology.org/"}]}],"caseSensitive":true,"content":"not-present"}}]}

#216

GET https://tx-nordics.fhir.org/fhir/r4/CodeSystem/d2cd8840-a2e8-439b-ba71-cc6c09083a0a HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
User-Agent: fhir/publisher

200
cache-control:no-cache
content-location:https://tx-nordics.fhir.org/fhir/r4/CodeSystem/d2cd8840-a2e8-439b-ba71-cc6c09083a0a/_history/1
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:28:13 GMT
etag:W/"1"
last-modified:Sun, 26 Oct 2025 17:16:30 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:a434dd96-5377-4492-af63-23e151fa4727
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:a434dd96-5377-4492-af63-23e151fa4727
x-xss-protection:0

{"resourceType":"CodeSystem","id":"d2cd8840-a2e8-439b-ba71-cc6c09083a0a","meta":{"versionId":"1","lastUpdated":"2025-10-26T18:16:30.924+01:00"},"text":{"status":"generated","div":"<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: CodeSystem HPO</b></p><a name=\"HPO\"/><a name=\"hcHPO\"/><p>This case-sensitive code system <code>http://human-phenotype-ontology.org</code> defines codes, but no codes are represented here</p></div>"},"url":"http://human-phenotype-ontology.org","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.6.339"}],"version":"1.0.0","name":"HPO","title":"Human Phenotype Ontology","status":"active","experimental":false,"date":"2022-06-02T00:00:00-00:00","contact":[{"name":"Peter Robinson or Melissa Haendel, The Monarch Initiative","telecom":[{"system":"url","value":"http://www.human-phenotype-ontology.org/"}]}],"description":"\"The Human Phenotype Ontology (HPO) provides a standardized vocabulary of phenotypic abnormalities encountered in human disease. Each term in the HPO describes a phenotypic abnormality, such as Atrial septal defect. The HPO is currently being developed using the medical literature, Orphanet, DECIPHER, and OMIM. HPO currently contains over 13,000 terms and over 156,000 annotations to hereditary diseases. The HPO project and others have developed software for phenotype-driven differential diagnostics, genomic diagnostics, and translational research. The HPO is a flagship product of the Monarch Initiative, an NIH-supported international consortium dedicated to semantic integration of biomedical and model organism data with the ultimate goal of improving biomedical research. The HPO, as a part of the Monarch Initiative, is a central component of one of the 13 driver projects in the Global Alliance for Genomics and Health (GA4GH) strategic roadmap.\"\r\n\r\nPlease see https://hpo.jax.org/app/download/ontology.\r\n\r\nReleases, produced approximately every 2 months, can be found [here](https://github.com/obophenotype/human-phenotype-ontology/releases).","copyright":"The HPO vocabularies, annotation files, tools and documentation are freely available. \r\n\r\n1. The HPO is copyrighted to protect the integrity of the vocabularies, which means that changes to the HPO vocabularies need to be done by HPO developers. However, anyone can download the HPO and use the ontologies or other HPO files under three conditions:\r\n\r\n* That the Human Phenotype Ontology Consortium is acknowledged and [cited](https://hpo.jax.org/app/citation) properly.\r\n* That any HPO Consortium file(s) displayed publicly include the date(s) and/or version number(s) of the relevant HPO file(s).\r\n* That neither the content of the HPO file(s) nor the logical relationships embedded within the HPO file(s) be altered in any way. (Content additions and modifications have to be suggested using our [issue tracker](https://github.com/obophenotype/human-phenotype-ontology/issues).)\r\n2. Users of the HPO should add the following statement to their online presence. This service/product uses the Human Phenotype Ontology (version information). Find out more at http://www.human-phenotype-ontology.org. We request that the HPO logo be included as well.","caseSensitive":true,"content":"not-present"}

#217

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":false,"include":[{"system":"http://human-phenotype-ontology.org","concept":[{"code":"HP:0000006","display":"Autosomal dominant inheritance"},{"code":"HP:0000007","display":"Autosomal recessive inheritance"},{"code":"HP:0001417","display":"X-linked inheritance"},{"code":"HP:0001419","display":"X-linked recessive inheritance"},{"code":"HP:0001423","display":"X-linked dominant inheritance"},{"code":"HP:0001426","display":"Multifactorial inheritance"},{"code":"HP:0001427","display":"Mitochondrial inheritance"},{"code":"HP:0001442","display":"Typified by somatic mosaicism"},{"code":"HP:0001450","display":"Y-linked inheritance"},{"code":"HP:0001470","display":"Sex-limited expression"},{"code":"HP:0003743","display":"Genetic anticipation"},{"code":"HP:0003745","display":"Sporadic"},{"code":"HP:0010983","display":"Oligogenic inheritance"},{"code":"HP:0012274","display":"Autosomal dominant inheritance with paternal imprinting"},{"code":"HP:0012275","display":"Autosomal dominant inheritance with maternal imprinting"},{"code":"HP:0025352","display":"Typically de novo"},{"code":"HP:0032113","display":"Semidominant inheritance"}]}]}}}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:28:14 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:4d06cad7-7f43-4202-a2fa-710ad512d751
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:4d06cad7-7f43-4202-a2fa-710ad512d751
x-xss-protection:0

{"resourceType":"ValueSet","status":"active","expansion":{"identifier":"urn:uuid:12d39b1f-d227-4b25-8b46-a753759515bc","timestamp":"2026-01-30T19:28:14+01:00","total":0,"offset":0,"parameter":[{"name":"used-codesystem","valueUri":"http://human-phenotype-ontology.org|1.0.0"},{"name":"version","valueUri":"http://human-phenotype-ontology.org|1.0.0"},{"name":"excludeNested","valueBoolean":false},{"name":"offset","valueInteger":0},{"name":"count","valueInteger":1000}]}}

#218

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$batch-validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

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400
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{"resourceType":"OperationOutcome","issue":[{"severity":"error","code":"not-supported","diagnostics":"Invalid request: The FHIR endpoint on this server does not know how to handle POST operation[ValueSet/$batch-validate-code] with parameters [[]]"},{"severity":"information","code":"informational","diagnostics":"X-Request-Id: ce16ae2d-65a6-497b-b716-67c8e10c19be"}]}

#219

GET https://tx-nordics.fhir.org/fhir/r4/CodeSystem?_format=json&url=http%3A%2F%2Fwww.sequenceontology.org HTTP/1.0
User-Agent: hapi-fhir-tooling-client
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200
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{"resourceType":"Bundle","id":"cdba1e05-7bac-3f5d-82c0-e3c9e9893aee","meta":{"lastUpdated":"2026-01-30T19:28:15.715+01:00","tag":[{"system":"http://terminology.hl7.org/CodeSystem/v3-ObservationValue","code":"SUBSETTED","display":"Resource encoded in summary mode"}]},"type":"searchset","total":1,"link":[{"relation":"self","url":"https://tx-nordics.fhir.org/fhir/r4/CodeSystem?_format=json&_summary=true&url=http%3A%2F%2Fwww.sequenceontology.org"}],"entry":[{"fullUrl":"https://tx-nordics.fhir.org/fhir/r4/CodeSystem/cff123ef-92c6-49ec-8363-22fb407eeeb0","resource":{"resourceType":"CodeSystem","id":"cff123ef-92c6-49ec-8363-22fb407eeeb0","meta":{"versionId":"1","lastUpdated":"2025-10-26T18:16:34.295+01:00","tag":[{"system":"http://terminology.hl7.org/CodeSystem/v3-ObservationValue","code":"SUBSETTED","display":"Resource encoded in summary mode"}]},"url":"http://www.sequenceontology.org","version":"1.0.0","name":"SO","title":"Sequence Ontology","status":"active","experimental":false,"date":"2023-12-11T00:00:00-00:00","publisher":"Sequence Ontology","contact":[{"name":"Sequence Ontology; Karen Eilbeck (PI), Barry Moore (Software Developer), Shawn Rynearson (Software Developer)","telecom":[{"system":"url","value":"http://www.sequenceontology.org"},{"system":"email","value":"keilbeck@genetics.utah.edu"},{"system":"email","value":"barry.moore@genetics.utah.edu"},{"system":"email","value":"shawn.rynearson@gmail.com"}]}],"caseSensitive":true,"content":"not-present"}}]}

#220

GET https://tx-nordics.fhir.org/fhir/r4/CodeSystem/cff123ef-92c6-49ec-8363-22fb407eeeb0 HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
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200
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content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:28:16 GMT
etag:W/"1"
last-modified:Sun, 26 Oct 2025 17:16:34 GMT
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{"resourceType":"CodeSystem","id":"cff123ef-92c6-49ec-8363-22fb407eeeb0","meta":{"versionId":"1","lastUpdated":"2025-10-26T18:16:34.295+01:00"},"text":{"status":"generated","div":"<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: CodeSystem SO</b></p><a name=\"SO\"/><a name=\"hcSO\"/><p>This case-sensitive code system <code>http://www.sequenceontology.org</code> defines codes, but no codes are represented here</p></div>"},"url":"http://www.sequenceontology.org","version":"1.0.0","name":"SO","title":"Sequence Ontology","status":"active","experimental":false,"date":"2023-12-11T00:00:00-00:00","publisher":"Sequence Ontology","contact":[{"name":"Sequence Ontology; Karen Eilbeck (PI), Barry Moore (Software Developer), Shawn Rynearson (Software Developer)","telecom":[{"system":"url","value":"http://www.sequenceontology.org"},{"system":"email","value":"keilbeck@genetics.utah.edu"},{"system":"email","value":"barry.moore@genetics.utah.edu"},{"system":"email","value":"shawn.rynearson@gmail.com"}]}],"description":"\"The Sequence Ontology is a set of terms and relationships used to describe the features and attributes of biological sequence. SO includes different kinds of features which can be located on the sequence. Biological features are those which are defined by their disposition to be involved in a biological process.\"\r\n\r\n\"The Sequence Ontologies are provided as a resource to the biological community. They have the following obvious uses:\r\n\r\n* To provide for a structured controlled vocabulary for the description of primary annotations of nucleic acid sequence, e.g. the annotations shared by a DAS server ([BioDAS](http://www.biodas.org/documents/das2/das2_protocol.html), [Biosapiens DAS](http://www.biosapiens.info/page.php?page=das_portal)), or annotations encoded by [GFF3](http://www.sequenceontology.org/gff3.shtml).\"\r\n\r\n* To provide for a structured representation of these annotations within databases. Were genes within model organism databases to be annotated with these terms then it would be possible to query all these databases for, for example, all genes whose transcripts are edited, or trans-spliced, or are bound by a particular protein. One such genomic database is [Chado](http://www.gmod.org/wiki/Chado).\r\n\r\n* To provide a structured controlled vocabulary for the description of mutations at both the sequence and more gross level in the context of genomic databases.\"\r\n\r\n\"The Sequence Ontology is part of [OBO](http://www.obofoundry.org/). It has close links to other ontology projects such as the [RNAO consortium](http://roc.bgsu.edu/), and the [Biosapiens polypeptide features](http://www.ebi.ac.uk/ontology-lookup/browse.do?ontName=BS).\"\r\n\r\nThe content can be browsed [here](http://www.sequenceontology.org/browser/obob.cgi)\r\n\r\nThe content can be downloaded [here](https://github.com/The-Sequence-Ontology/SO-Ontologies)\r\n\r\nFor information on contributing, please see [here](https://github.com/The-Sequence-Ontology/SO-Ontologies#contributing)\r\n\r\nTo request a term or register feedback, see [here](https://github.com/The-Sequence-Ontology/SO-Ontologies/issues)","copyright":"The Sequence Ontology: A tool for the unification of genome annotations. Eilbeck K., Lewis S.E., Mungall C.J., Yandell M., Stein L., Durbin R., Ashburner M. [Genome Biology (2005) 6:R44](http://genomebiology.com/2005/6/5/R44)\r\n\r\nPlease also include the version of SO used.\r\n\r\nSequence Ontology data and data products are licensed under the [Creative Commons Attribution 4.0 Unported License](https://creativecommons.org/licenses/by/4.0/legalcode).","caseSensitive":true,"content":"not-present"}

#221

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
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200
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0002072"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#222

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
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{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001536"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001536"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#223

GET https://tx.fhir.org/r4/CodeSystem?_format=json&url=http%3A%2F%2Floinc.org HTTP/1.0
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Accept: application/fhir+json; fhirVersion=4.0

200
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#224

POST https://tx.fhir.org/r4/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
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server:nginx
x-request-id:253-23568947

{"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:c60f70a3-0d9b-44a9-8d70-f8d2615e7e69","timestamp" : "2026-01-30T18:28:17.521Z","total" : 19,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://loinc.org|2.81"}],"contains" : [{"system" : "http://loinc.org","code" : "LA10315-2","display" : "Ultrarapid metabolizer"},{"system" : "http://loinc.org","code" : "LA25391-6","display" : "Normal metabolizer"},{"system" : "http://loinc.org","code" : "LA25390-8","display" : "Rapid metabolizer"},{"system" : "http://loinc.org","code" : "LA10317-8","display" : "Intermediate metabolizer"},{"system" : "http://loinc.org","code" : "LA9657-3","display" : "Poor metabolizer"},{"system" : "http://loinc.org","code" : "LA19542-2","display" : "Low risk"},{"system" : "http://loinc.org","code" : "LA19541-4","display" : "High risk"},{"system" : "http://loinc.org","code" : "LA6676-6","display" : "Resistant"},{"system" : "http://loinc.org","code" : "LA6677-4","display" : "Responsive"},{"system" : "http://loinc.org","code" : "LA9660-7","display" : "Presumed resistant"},{"system" : "http://loinc.org","code" : "LA9661-5","display" : "Presumed responsive"},{"system" : "http://loinc.org","code" : "LA6682-4","display" : "Unknown Significance"},{"system" : "http://loinc.org","code" : "LA6675-8","display" : "Benign"},{"system" : "http://loinc.org","code" : "LA6674-1","display" : "Presumed Benign"},{"system" : "http://loinc.org","code" : "LA9662-3","display" : "Presumed non-responsive"},{"system" : "http://loinc.org","code" : "LA25392-4","display" : "Increased function"},{"system" : "http://loinc.org","code" : "LA25393-2","display" : "Normal function"},{"system" : "http://loinc.org","code" : "LA25395-7","display" : "Decreased function"},{"system" : "http://loinc.org","code" : "LA25394-0","display" : "Poor function"}]}}

#225

POST https://tx.fhir.org/r4/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":false,"include":[{"system":"http://snomed.info/sct","concept":[{"code":"444734003","display":"Does not meet eligibility criteria for clinical trial (finding)"},{"code":"399223003","display":"Patient eligible for clinical trial (finding)"}]}]}}}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:737
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:28:17 GMT
last-modified:Fri, 30 Jan 2026 18:28:17 GMT
pragma:no-cache
server:nginx
x-request-id:253-23568951

{"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:f461b980-138f-4f22-ad86-3e85d54bad53","timestamp" : "2026-01-30T18:28:17.599Z","total" : 2,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201"}],"contains" : [{"system" : "http://snomed.info/sct","code" : "444734003","display" : "Does not meet eligibility criteria for clinical trial (finding)"},{"system" : "http://snomed.info/sct","code" : "399223003","display" : "Patient eligible for clinical trial (finding)"}]}}

#226

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0002072"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:28:18 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:4464b6aa-8a87-42d6-949d-3728e4ee0245
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:4464b6aa-8a87-42d6-949d-3728e4ee0245
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0002072"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#227

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001060"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:28:18 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:3e13bdd6-71c5-429e-935d-ff9b80669687
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:3e13bdd6-71c5-429e-935d-ff9b80669687
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001060"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#228

GET https://tx-nordics.fhir.org/fhir/r4/CodeSystem?_format=json&url=http%3A%2F%2Fwww.genenames.org HTTP/1.0
User-Agent: hapi-fhir-tooling-client
Accept: application/fhir+json; fhirVersion=4.0

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:28:19 GMT
etag:W/"1767559514802"
last-modified:Fri, 30 Jan 2026 18:28:19 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:d09b591c-4de3-4515-805f-b75a7234e9bb
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:d09b591c-4de3-4515-805f-b75a7234e9bb
x-xss-protection:0

{"resourceType":"Bundle","id":"a6d527f8-99fa-3d97-a9b4-a22f270dc351","meta":{"lastUpdated":"2026-01-30T19:28:19.149+01:00","tag":[{"system":"http://terminology.hl7.org/CodeSystem/v3-ObservationValue","code":"SUBSETTED","display":"Resource encoded in summary mode"}]},"type":"searchset","total":1,"link":[{"relation":"self","url":"https://tx-nordics.fhir.org/fhir/r4/CodeSystem?_format=json&_summary=true&url=http%3A%2F%2Fwww.genenames.org"}],"entry":[{"fullUrl":"https://tx-nordics.fhir.org/fhir/r4/CodeSystem/da87e0c1-0cd3-4626-ae64-e31f6256ec86","resource":{"resourceType":"CodeSystem","id":"da87e0c1-0cd3-4626-ae64-e31f6256ec86","meta":{"versionId":"1","lastUpdated":"2025-10-26T18:16:35.403+01:00","tag":[{"system":"http://terminology.hl7.org/CodeSystem/v3-ObservationValue","code":"SUBSETTED","display":"Resource encoded in summary mode"}]},"url":"http://www.genenames.org","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.6.281"}],"version":"3.1.0","name":"HGNCGenes","title":"HUGO Gene Nomenclature Committee Genes","status":"active","experimental":false,"date":"2024-08-22T00:00:00-00:00","publisher":"HUGO Gene Nomenclature Committee","contact":[{"name":"HUGO Gene Nomenclature Committee","telecom":[{"system":"url","value":"https://www.genenames.org/"},{"system":"email","value":"hgnc@genenames.org"}]}],"caseSensitive":true,"content":"not-present"}}]}

#229

GET https://tx-nordics.fhir.org/fhir/r4/CodeSystem/da87e0c1-0cd3-4626-ae64-e31f6256ec86 HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
User-Agent: fhir/publisher

200
cache-control:no-cache
content-location:https://tx-nordics.fhir.org/fhir/r4/CodeSystem/da87e0c1-0cd3-4626-ae64-e31f6256ec86/_history/1
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:28:19 GMT
etag:W/"1"
last-modified:Sun, 26 Oct 2025 17:16:35 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:c58410ed-3611-4d88-85d1-605922724421
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:c58410ed-3611-4d88-85d1-605922724421
x-xss-protection:0

{"resourceType":"CodeSystem","id":"da87e0c1-0cd3-4626-ae64-e31f6256ec86","meta":{"versionId":"1","lastUpdated":"2025-10-26T18:16:35.403+01:00"},"text":{"status":"generated","div":"<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: CodeSystem v3-hgnc</b></p><a name=\"v3-hgnc\"/><a name=\"hcv3-hgnc\"/><p>This case-sensitive code system <code>http://www.genenames.org</code> defines codes, but no codes are represented here</p></div>"},"url":"http://www.genenames.org","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.6.281"}],"version":"3.1.0","name":"HGNCGenes","title":"HUGO Gene Nomenclature Committee Genes","status":"active","experimental":false,"date":"2024-08-22T00:00:00-00:00","publisher":"HUGO Gene Nomenclature Committee","contact":[{"name":"HUGO Gene Nomenclature Committee","telecom":[{"system":"url","value":"https://www.genenames.org/"},{"system":"email","value":"hgnc@genenames.org"}]}],"description":"\"The HGNC is responsible for approving unique symbols and names for human loci, including protein coding genes, ncRNA genes and pseudogenes, to allow unambiguous scientific communication.\"\r\n\r\nThe HGNC gene table carries gene IDs, gene symbols and full gene names. Guidance from HGNC confirms that gene symbols are not unique across species and have been known to change in some instances. Thus the commonly used gene symbols should be encoded in FHIR as \"displays\" with the corresponding IDs (beginning with \"HGNC:\") as the \"codes\".\r\n\r\n\"For each known human gene we approve a gene name and symbol (short-form abbreviation). All approved symbols are stored in the HGNC database,[www.genenames.org](https://www.genenames.org/tools/search), a curated online repository of HGNC-approved gene nomenclature, gene groups and associated resources including links to genomic, proteomic and phenotypic information. Each symbol is unique and we ensure that each gene is only given one approved gene symbol. It is necessary to provide a unique symbol for each gene so that we and others can talk about them, and this also facilitates electronic data retrieval from publications and databases.\"\r\n\r\nHGNC also provides an index on gene families/groups. GeneGroup IDs do not begin with \"HGNC:\", so care must be made to ensure alignment of concepts when viewing an HGNC ID from an older system that may be referring to the GeneID and not a gene group. For example, 588 refers to the HLA gene family, but HGNC:588 identifies the ATG12 gene. To provide clarity for systems that do not distinguish codes from genes and gene families, use \"http://www.genenames.org\" for genes and \"http://www.genenames.org/genegroup\" for gene families as code system URIs.\r\n\r\nFor more information on HGNC Gene Groups, see [https://terminology.hl7.org/CodeSystem-HGNCGeneGroup.html](https://terminology.hl7.org/CodeSystem-HGNCGeneGroup.html).\r\n\r\nHistorically, HGNC gene symbols were used with the HL7 coded data type. For example, in the HL7 messages specified according to the HL7 V2 Clinical Genomics Fully LOINC-Qualified Genetic Variation Model Implementation Guide, HGNC gene symbols were used as the observation values for gene identifiers. For example, OBX 1 CWE 48018-6^Gene identifier^ BRCA1^HGNC. Please note that gene symbols may be present in legacy systems, but GeneID should be used to exchange HGNC gene information in current implementations.\r\n\r\nHGNC is a free database for the public.\r\n\r\nVersioning Information: The version of the HGNC database is reported using the last updated date. The last updated date is posted on the main HGNC Search screen in the format like \"2024-07-25\".\r\n\r\nCurrent, monthly and quarterly HGNC dataset files are published.\r\n\r\nPlease see https://www.genenames.org/ for more info.","copyright":"It is a condition of HGNC funding from NIH and the Welcome Trust that the nomenclature and information provided is freely available to all. Anyone may use the HGNC data, but we request that they reference the *\"HUGO Gene Nomenclature Committee at the European Bioinformatics Institute\"* and the website where possible.","caseSensitive":true,"content":"not-present"}

#230

GET https://tx-nordics.fhir.org/fhir/r4/CodeSystem?_format=json&url=http%3A%2F%2Fwww.genenames.org%2Fgenegroup HTTP/1.0
User-Agent: hapi-fhir-tooling-client
Accept: application/fhir+json; fhirVersion=4.0

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:28:20 GMT
etag:W/"1765496486211"
last-modified:Fri, 30 Jan 2026 18:28:20 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:9256e059-05c7-4367-88be-3280cf4f60ec
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:9256e059-05c7-4367-88be-3280cf4f60ec
x-xss-protection:0

{"resourceType":"Bundle","id":"2b1d53b8-e225-3978-8ed2-757f828f61e0","meta":{"lastUpdated":"2026-01-30T19:28:20.228+01:00","tag":[{"system":"http://terminology.hl7.org/CodeSystem/v3-ObservationValue","code":"SUBSETTED","display":"Resource encoded in summary mode"}]},"type":"searchset","total":1,"link":[{"relation":"self","url":"https://tx-nordics.fhir.org/fhir/r4/CodeSystem?_format=json&_summary=true&url=http%3A%2F%2Fwww.genenames.org%2Fgenegroup"}],"entry":[{"fullUrl":"https://tx-nordics.fhir.org/fhir/r4/CodeSystem/d5f743be-5535-4d85-8981-8e429b572640","resource":{"resourceType":"CodeSystem","id":"d5f743be-5535-4d85-8981-8e429b572640","meta":{"versionId":"1","lastUpdated":"2025-10-26T18:16:30.787+01:00","tag":[{"system":"http://terminology.hl7.org/CodeSystem/v3-ObservationValue","code":"SUBSETTED","display":"Resource encoded in summary mode"}]},"url":"http://www.genenames.org/genegroup","version":"1.1.0","name":"HGNCGeneGroup","title":"HUGO Gene Nomenclature Committee Gene Group","status":"active","experimental":false,"date":"2024-08-22T00:00:00-00:00","publisher":"HUGO Gene Nomenclature Committee","contact":[{"name":"HUGO Gene Nomenclature Committee","telecom":[{"system":"url","value":"https://www.genenames.org/"},{"system":"email","value":"hgnc@genenames.org"}]}],"caseSensitive":true,"content":"not-present"}}]}

#231

GET https://tx-nordics.fhir.org/fhir/r4/CodeSystem/d5f743be-5535-4d85-8981-8e429b572640 HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
User-Agent: fhir/publisher

200
cache-control:no-cache
content-location:https://tx-nordics.fhir.org/fhir/r4/CodeSystem/d5f743be-5535-4d85-8981-8e429b572640/_history/1
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:28:20 GMT
etag:W/"1"
last-modified:Sun, 26 Oct 2025 17:16:30 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:501831a1-2695-430c-8e0e-8b038a52d310
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:501831a1-2695-430c-8e0e-8b038a52d310
x-xss-protection:0

{"resourceType":"CodeSystem","id":"d5f743be-5535-4d85-8981-8e429b572640","meta":{"versionId":"1","lastUpdated":"2025-10-26T18:16:30.787+01:00"},"text":{"status":"generated","div":"<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: CodeSystem HGNCGeneGroup</b></p><a name=\"HGNCGeneGroup\"/><a name=\"hcHGNCGeneGroup\"/><p>This case-sensitive code system <code>http://www.genenames.org/genegroup</code> defines codes, but no codes are represented here</p></div>"},"url":"http://www.genenames.org/genegroup","version":"1.1.0","name":"HGNCGeneGroup","title":"HUGO Gene Nomenclature Committee Gene Group","status":"active","experimental":false,"date":"2024-08-22T00:00:00-00:00","publisher":"HUGO Gene Nomenclature Committee","contact":[{"name":"HUGO Gene Nomenclature Committee","telecom":[{"system":"url","value":"https://www.genenames.org/"},{"system":"email","value":"hgnc@genenames.org"}]}],"description":"\"The HGNC is responsible for approving unique symbols and names for human loci, including protein coding genes, ncRNA genes and pseudogenes, to allow unambiguous scientific communication.\"\r\n\r\nHGNC Gene Group is an index on gene families/groups. The numeric GeneGroup IDs should be used as codes. GeneGroup IDs do not begin with \"HGNC:\" (like the GeneIDs for genes in HGNC Genes), so care must be made to ensure alignment of concepts when viewing an HGNC ID from an older system that may be referring to the GeneID and not a gene group. For example, 588 refers to the HLA gene family, but HGNC:588 identifies the ATG12 gene. To provide clarity for systems that do not distinguish codes from genes and gene families, use \"http://www.genenames.org\" for genes and \"http://www.genenames.org/genegroup\" for gene families as code system URIs.\r\n\r\n\"For each known human gene we approve a gene name and symbol (short-form abbreviation). All approved symbols are stored in the HGNC database,[www.genenames.org](https://www.genenames.org/tools/search), a curated online repository of HGNC-approved gene nomenclature, gene groups and associated resources including links to genomic, proteomic and phenotypic information. Each symbol is unique and we ensure that each gene is only given one approved gene symbol. It is necessary to provide a unique symbol for each gene so that we and others can talk about them, and this also facilitates electronic data retrieval from publications and databases.\"\r\n\r\nFor more information on the use of HGNC Genes, see [https://terminology.hl7.org/CodeSystem-v3-hgnc.html](https://terminology.hl7.org/CodeSystem-v3-hgnc.html).\r\n\r\nHGNC is a free database for the public.\r\n\r\nPlease see https://www.genenames.org/ for more info.","copyright":"It is a condition of HGNC funding from NIH and the Welcome Trust that the nomenclature and information provided is freely available to all. Anyone may use the HGNC data, but we request that they reference the *\"HUGO Gene Nomenclature Committee at the European Bioinformatics Institute\"* and the website where possible.","caseSensitive":true,"content":"not-present"}

#232

POST https://tx.fhir.org/r4/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
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: "Esophageal fistula"},{"code" : "C143482","display" : "Fecal incontinence"},{"code" : "C57807","display" : "Flatulence"},{"code" : "C143499","display" : "Gastric fistula"},{"code" : "C143500","display" : "Gastric hemorrhage"},{"code" : "C143501","display" : "Gastric necrosis"},{"code" : "C143502","display" : "Gastric perforation"},{"code" : "C143503","display" : "Gastric stenosis"},{"code" : "C143504","display" : "Gastric ulcer"},{"code" : "C57812","display" : "Gastritis"},{"code" : "C143506","display" : "Gastroesophageal reflux disease"},{"code" : "C143508","display" : "Gastrointestinal disorders - Other, specify"},{"code" : "C146637","display" : "Gastrointestinal fistula"},{"code" : "C57814","display" : "Ileus"},{"code" : "C143510","display" : "Gastrointestinal pain"},{"code" : "C143512","display" : "Gastroparesis"},{"code" : "C146626","display" : "Gingival pain"},{"code" : "C143537","display" : "Hemorrhoidal hemorrhage"},{"code" : "C146738","display" : "Hemorrhoids"},{"code" : "C146633","display" : "Ileal perforation"},{"code" : "C143578","display" : "Ileal stenosis"},{"code" : "C57821","display" : "Ileal fistula"},{"code" : "C56542","display" : "Ileal hemorrhage"},{"code" : "C57823","display" : "Ileal obstruction"},{"code" : "C57826","display" : "Ileal ulcer"},{"code" : "C143595","display" : "Intra-abdominal hemorrhage"},{"code" : "C143622","display" : "Jejunal perforation"},{"code" : "C143623","display" : "Jejunal stenosis"},{"code" : "C57827","display" : "Jejunal fistula"},{"code" : "C56543","display" : "Jejunal hemorrhage"},{"code" : "C57829","display" : "Jejunal obstruction"},{"code" : "C57832","display" : "Jejunal ulcer"},{"code" : "C146761","display" : "Lip pain"},{"code" : "C143656","display" : "Lower gastrointestinal hemorrhage"},{"code" : "C57838","display" : "Malabsorption"},{"code" : "C143679","display" : "Mucositis oral"},{"code" : "C146764","display" : "Nausea"},{"code" : "C143710","display" : "Obstruction gastric"},{"code" : "C143715","display" : "Oral cavity fistula"},{"code" : "C56551","display" : "Oral hemorrhage"},{"code" : "C143716","display" : "Oral dysesthesia"},{"code" : "C146627","display" : "Oral pain"},{"code" : "C57845","display" : "Pancreatic fistula"},{"code" : "C56554","display" : "Pancreatic hemorrhage"},{"code" : "C143730","display" : "Pancreatic duct stenosis"},{"code" : "C143732","display" : "Pancreatic necrosis"},{"code" : "C146789","display" : "Pancreatitis"},{"code" : "C57849","display" : "Periodontal disease"},{"code" : "C57850","display" : "Peritoneal necrosis"},{"code" : "C57857","display" : "Proctitis"},{"code" : "C143200","display" : "Rectal fissure"},{"code" : "C143802","display" : "Rectal mucositis"},{"code" : "C146631","display" : "Rectal pain"},{"code" : "C146634","display" : "Rectal perforation"},{"code" : "C143803","display" : "Rectal stenosis"},{"code" : "C57859","display" : "Rectal fistula"},{"code" : "C56560","display" : "Rectal hemorrhage"},{"code" : "C57863","display" : "Rectal necrosis"},{"code" : "C57864","display" : "Rectal obstruction"},{"code" : "C57867","display" : "Rectal ulcer"},{"code" : "C146632","display" : "Retroperitoneal hemorrhage"},{"code" : "C143821","display" : "Salivary duct inflammation"},{"code" : "C57868","display" : "Salivary gland fistula"},{"code" : "C143842","display" : "Small intestinal mucositis"},{"code" : "C143843","display" : "Small intestinal obstruction"},{"code" : "C146635","display" : "Small intestinal perforation"},{"code" : "C143844","display" : "Small intestinal stenosis"},{"code" : "C143846","display" : "Small intestine ulcer"},{"code" : "C146774","display" : "Stomach pain"},{"code" : "C143876","display" : "Tooth development disorder"},{"code" : "C143877","display" : "Tooth discoloration"},{"code" : "C143879","display" : "Toothache"},{"code" : "C146730","display" : "Typhlitis"},{"code" : "C143895","display" : "Upper gastrointestinal hemorrhage"},{"code" : "C143938","display" : "Visceral arterial ischemia"},{"code" : "C57896","display" : "Vomiting"},{"code" : "C143366","display" : "Chills"},{"code" : "C143395","display" : "Death neonatal"},{"code" : "C143396","display" : "Death NOS"},{"code" : "C143201","display" : "Disease progression"},{"code" : "C143432","display" : "Edema face"},{"code" : "C143433","display" : "Edema limbs"},{"code" : "C143434","display" : "Edema trunk"},{"code" : "C143474","display" : "Facial pain"},{"code" : "C146753","display" : "Fatigue"},{"code" : "C143485","display" : "Fever"},{"code" : "C143492","display" : "Flu like symptoms"},{"code" : "C143496","display" : "Gait disturbance"},{"code" : "C143513","display" : "General disorders and administration site conditions - Other, specify"},{"code" : "C143202","display" : "Generalized edema"},{"code" : "C55332","display" : "Hypothermia"},{"code" : "C143584","display" : "Infusion site extravasation"},{"code" : "C143585","display" : "Injection site reaction"},{"code" : "C143654","display" : "Localized edema"},{"code" : "C143665","display" : "Malaise"},{"code" : "C143680","display" : "Multi-organ failure"},{"code" : "C143700","display" : "Neck edema"},{"code" : "C143707","display" : "Non-cardiac chest pain"},{"code" : "C143725","display" : "Pain"},{"code" : "C143863","display" : "Sudden death NOS"},{"code" : "C143203","display" : "Vaccination site lymphadenopathy"},{"code" : "C143314","display" : "Bile duct stenosis"},{"code" : "C143316","display" : "Biliary fistula"},{"code" : "C143204","display" : "Budd-Chiari syndrome"},{"code" : "C57808","display" : "Gallbladder fistula"},{"code" : "C146735","display" : "Gallbladder necrosis"},{"code" : "C57810","display" : "Gallbladder obstruction"},{"code" : "C146755","display" : "Gallbladder pain"},{"code" : "C146708","display" : "Gallbladder perforation"},{"code" : "C143539","display" : "Hepatic failure"},{"code" : "C143540","display" : "Hepatic hemorrhage"},{"code" : "C146736","display" : "Hepatic necrosis"},{"code" : "C143542","display" : "Hepatic pain"},{"code" : "C143544","display" : "Hepatobiliary disorders - Other, specify"},{"code" : "C143742","display" : "Perforation bile duct"},{"code" : "C143769","display" : "Portal hypertension"},{"code" : "C143770","display" : "Portal vein thrombosis"},{"code" : "C143205","display" : "Sinusoidal obstruction syndrome"},{"code" : "C143271","display" : "Allergic reaction"},{"code" : "C143282","display" : "Anaphylaxis"},{"code" : "C143310","display" : "Autoimmune disorder"},{"code" : "C143394","display" : "Cytokine release syndrome"},{"code" : "C143580","display" : "Immune system disorders - Other, specify"},{"code" : "C146642","display" : "Serum sickness"},{"code" : "C143254","display" : "Abdominal infection"},{"code" : "C143285","display" : "Anorectal infection"},{"code" : "C143293","display" : "Appendicitis perforated"},{"code" : "C143294","display" : "Appendicitis"},{"code" : "C143297","display" : "Arteritis infective"},{"code" : "C143206","display" : "Bacteremia"},{"code" : "C143317","display" : "Biliary tract infection"},{"code" : "C143319","display" : "Bladder infection"},{"code" : "C143331","display" : "Bone infection"},{"code" : "C143336","display" : "Breast infection"},{"code" : "C143339","display" : "Bronchial infection"},{"code" : "C143356","display" : "Catheter related infection"},{"code" : "C143359","display" : "Cecal infection"},{"code" : "C143362","display" : "Cervicitis infection"},{"code" : "C143383","display" : "Conjunctivitis infective"},{"code" : "C143384","display" : "Conjunctivitis"},{"code" : "C143386","display" : "Corneal infection"},{"code" : "C143390","display" : "Cranial nerve infection"},{"code" : "C143207","display" : "Cytomegalovirus infection reactivation"},{"code" : "C143406","display" : "Device related infection"},{"code" : "C143415","display" : "Duodenal infection"},{"code" : "C143438","display" : "Encephalitis infection"},{"code" : "C143439","display" : "Encephalomyelitis infection"},{"code" : "C143441","display" : "Endocarditis infective"},{"code" : "C143443","display" : "Endophthalmitis"},{"code" : "C143444","display" : "Enterocolitis infectious"},{"code" : "C143208","display" : "Epstein-Barr virus infection reactivation"},{"code" : "C143454","display" : "Esophageal infection"},{"code" : "C143469","display" : "Eye infection"},{"code" : "C143209","display" : "Folliculitis"},{"code" : "C143210","display" : "Fungemia"},{"code" : "C143497","display" : "Gallbladder infection"},{"code" : "C143523","display" : "Gum infection"},{"code" : "C143541","display" : "Hepatic infection"},{"code" : "C143211","display" : "Hepatitis B reactivation"},{"code" : "C143543","display" : "Hepatitis viral"},{"code" : "C143212","display" : "Herpes simplex reactivation"},{"code" : "C143581","display" : "Infections and infestations - Other, specify"},{"code" : "C143582","display" : "Infective myositis"},{"code" : "C143626","display" : "Joint infection"},{"code" : "C143632","display" : "Kidney infection"},{"code" : "C143641","display" : "Laryngitis"},{"code" : "C143651","display" : "Lip infection"},{"code" : "C143657","display" : "Lung infection"},{"code" : "C143658","display" : "Lymph gland infection"},{"code" : "C143667","display" : "Mediastinal infection"},{"code" : "C143670","display" : "Meningitis"},{"code" : "C143678","display" : "Mucosal infection"},{"code" : "C55459","display" : "Myelitis"},{"code" : "C143695","display" : "Nail infection"},{"code" : "C143719","display" : "Otitis externa"},{"code" : "C143720","display" : "Otitis media"},{"code" : "C143721","display" : "Ovarian infection"},{"code" : "C143728","display" : "Pancreas infection"},{"code" : "C143735","display" : "Papulopustular rash"},{"code" : "C143737","display" : "Paronychia"},{"code" : "C143740","display" : "Pelvic infection"},{"code" : "C143741","display" : "Penile infection"},{"code" : "C143748","display" : "Periorbital infection"},{"code" : "C143751","display" : "Peripheral nerve infection"},{"code" : "C143753","display" : "Peritoneal infection"},{"code" : "C143758","display" : "Pharyngitis"},{"code" : "C143760","display" : "Phlebitis infective"},{"code" : "C143766","display" : "Pleural infection"},{"code" : "C143783","display" : "Prostate infection"},{"code" : "C143800","display" : "Rash pustular"},{"code" : "C143819","display" : "Rhinitis infective"},{"code" : "C143822","display" : "Salivary gland infection"},{"code" : "C143825","display" : "Scrotal infection"},{"code" : "C143827","display" : "Sepsis"},{"code" : "C143213","display" : "Shingles"},{"code" : "C143832","display" : "Sinusitis"},{"code" : "C143838","display" : "Skin infection"},{"code" : "C143845","display" : "Small intestine infection"},{"code" : "C143849","display" : "Soft tissue infection"},{"code" : "C143857","display" : "Splenic infection"},{"code" : "C143860","display" : "Stoma site infection"},{"code" : "C143214","display" : "Thrush"},{"code" : "C143878","display" : "Tooth infection"},{"code" : "C143884","display" : "Tracheitis"},{"code" : "C143896","display" : "Upper respiratory infection"},{"code" : "C143899","display" : "Urethral infection"},{"code" : "C143904","display" : "Urinary tract infection"},{"code" : "C143917","display" : "Uterine infection"},{"code" : "C143924","display" : "Vaginal infection"},{"code" : "C143215","display" : "Viremia"},{"code" : "C143943","display" : "Vulval infection"},{"code" : "C143951","display" : "Wound infection"},{"code" : "C143284","display" : "Ankle fracture"},{"code" : "C143289","display" : "Aortic injury"},{"code" : "C143296","display" : "Arterial injury"},{"code" : "C143315","display" : "Biliary anastomotic leak"},{"code" : "C143318","display" : "Bladder anastomotic leak"},{"code" : "C143345","display" : "Bruising"},{"code" : "C57900","display" : "Burn"},{"code" : "C143405","display" : "Dermatitis radiation"},{"code" : "C143451","display" : "Esophageal anastomotic leak"},{"code" : "C143475","display" : "Fall"},{"code" : "C143476","display" : "Fallopian tube anastomotic leak"},{"code" : "C146714","display" : "Fallopian tube perforation"},{"code" : "C58382","display" : "Fracture"},{"code" : "C143498","display" : "Gastric anastomotic leak"},{"code" : "C143507","display" : "Gastrointestinal anastomotic leak"},{"code" : "C143511","display" : "Gastrointestinal stoma necrosis"},{"code" : "C143546","display" : "Hip fracture"},{"code" : "C56735","display" : "Injury to inferior vena cava"},{"code" : "C143583","display" : "Infusion related reaction"},{"code" : "C143586","display" : "Injury to carotid artery"},{"code" : "C143587","display" : "Injury to jugular vein"},{"code" : "C143588","display" : "Injury to superior vena cava"},{"code" : "C143589","display" : "Injury, poisoning and procedural complications - Other, specify"},{"code" : "C143592","display" : "Intestinal stoma leak"},{"code" : "C143593","display" : "Intestinal stoma obstruction"},{"code" : "C143594","display" : "Intestinal stoma site bleeding"},{"code" : "C143597","display" : "Intraoperative arterial injury"},{"code" : "C143598","display" : "Intraoperative breast injury"},{"code" : "C143599","display" : "Intraoperative cardiac injury"},{"code" : "C143600","display" : "Intraoperative ear injury"},{"code" : "C143601","display" : "Intraoperative endocrine injury"},{"code" : "C143602","display" : "Intraoperative gastrointestinal injury"},{"code" : "C143603","display" : "Intraoperative head and neck injury"},{"code" : "C143604","display" : "Intraoperative hemorrhage"},{"code" : "C143605","display" : "Intraoperative hepatobiliary injury"},{"code" : "C143606","display" : "Intraoperative musculoskeletal injury"},{"code" : "C143607","display" : "Intraoperative neurological injury"},{"code" : "C143608","display" : "Intraoperative ocular injury"},{"code" : "C143609","display" : "Intraoperative renal injury"},{"code" : "C143610","display" : "Intraoperative reproductive tract injury"},{"code" : "C143611","display" : "Intraoperative respiratory injury"},{"code" : "C143612","display" : "Intraoperative splenic injury"},{"code" : "C143613","display" : "Intraoperative urinary injury"},{"code" : "C143614","display" : "Intraoperative venous injury"},{"code" : "C143631","display" : "Kidney anastomotic leak"},{"code" : "C143635","display" : "Large intestinal anastomotic leak"},{"code" : "C143729","display" : "Pancreatic anastomotic leak"},{"code" : "C143755","display" : "Pharyngeal anastomotic leak"},{"code" : "C143772","display" : "Postoperative hemorrhage"},{"code" : "C143773","display" : "Postoperative thoracic procedure complication"},{"code" : "C143781","display" : "Prolapse of intestinal stoma"},{"code" : "C143782","display" : "Prolapse of urostomy"},{"code" : "C143796","display" : "Radiation recall reaction (dermatologic)"},{"code" : "C143801","display" : "Rectal anastomotic leak"},{"code" : "C58401","display" : "Seroma"},{"code" : "C143841","display" : "Small intestinal anastomotic leak"},{"code" : "C143855","display" : "Spermatic cord anastomotic leak"},{"code" : "C143856","display" : "Spinal fracture"},{"code" : "C143858","display" : "Stenosis of gastrointestinal stoma"},{"code" : "C146694","display" : "Stomal ulcer"},{"code" : "C56567","display" : "Tracheal hemorrhage"},{"code" : "C143882","display" : "Tracheal obstruction"},{"code" : "C143885","display" : "Tracheostomy site bleeding"},{"code" : "C143897","display" : "Ureteric anastomotic leak"},{"code" : "C143898","display" : "Urethral anastomotic leak"},{"code" : "C143910","display" : "Urostomy leak"},{"code" : "C143911","display" : "Urostomy obstruction"},{"code" : "C143912","display" : "Urostomy site bleeding"},{"code" : "C143913","display" : "Urostomy stenosis"},{"code" : "C143915","display" : "Uterine anastomotic leak"},{"code" : "C143919","display" : "Uterine perforation"},{"code" : "C143216","display" : "Vaccination complication"},{"code" : "C143921","display" : "Vaginal anastomotic leak"},{"code" : "C143928","display" : "Vas deferens anastomotic leak"},{"code" : "C143929","display" : "Vascular access complication"},{"code" : "C143933","display" : "Venous injury"},{"code" : "C143949","display" : "Wound complication"},{"code" : "C143950","display" : "Wound dehiscence"},{"code" : "C143952","display" : "Wrist fracture"},{"code" : "C143261","display" : "Activated partial thromboplastin time prolonged"},{"code" : "C143267","display" : "Alanine aminotransferase increased"},{"code" : "C143269","display" : "Alkaline phosphatase increased"},{"code" : "C143301","display" : "Aspartate aminotransferase increased"},{"code" : "C143324","display" : "Blood antidiuretic hormone abnormal"},{"code" : "C143217","display" : "Blood bicarbonate decreased"},{"code" : "C143325","display" : "Blood bilirubin increased"},{"code" : "C143326","display" : "Blood corticotrophin decreased"},{"code" : "C143327","display" : "Blood gonadotrophin abnormal"},{"code" : "C143218","display" : "Blood lactate dehydrogenase increased"},{"code" : "C143328","display" : "Blood prolactin abnormal"},{"code" : "C143350","display" : "Carbon monoxide diffusing capacity decreased"},{"code" : "C143353","display" : "Cardiac troponin I increased"},{"code" : "C143354","display" : "Cardiac troponin T increased"},{"code" : "C143357","display" : "CD4 lymphocytes decreased"},{"code" : "C143368","display" : "Cholesterol high"},{"code" : "C143389","display" : "CPK increased"},{"code" : "C143391","display" : "Creatinine increased"},{"code" : "C143436","display" : "Ejection fraction decreased"},{"code" : "C143437","display" : "Electrocardiogram QT corrected interval prolonged"},{"code" : "C143219","display" : "Electrocardiogram T wave abnormal"},{"code" : "C143486","display" : "Fibrinogen decreased"},{"code" : "C143494","display" : "Forced expiratory volume decreased"},{"code" : "C143516","display" : "GGT increased"},{"code" : "C143521","display" : "Growth hormone abnormal"},{"code" : "C143526","display" : "Haptoglobin decreased"},{"code" : "C143533","display" : "Hemoglobin increased"},{"code" : "C143590","display" : "INR increased"},{"code" : "C143615","display" : "Investigations - Other, specify"},{"code" : "C143652","display" : "Lipase increased"},{"code" : "C143662","display" : "Lymphocyte count decreased"},{"code" : "C143663","display" : "Lymphocyte count increased"},{"code" : "C143704","display" : "Neutrophil count decreased"},{"code" : "C143731","display" : "Pancreatic enzymes decreased"},{"code" : "C143764","display" : "Platelet count decreased"},{"code" : "C143829","display" : "Serum amylase increased"},{"code" : "C143220","display" : "Thyroid stimulating hormone increased"},{"code" : "C143909","display" : "Urine output decreased"},{"code" : "C143939","display" : "Vital capacity abnormal"},{"code" : "C55338","display" : "Weight gain"},{"code" : "C55339","display" : "Weight loss"},{"code" : "C143948","display" : "White blood cell decreased"},{"code" : "C143259","display" : "Acidosis"},{"code" : "C143268","display" : "Alcohol intolerance"},{"code" : "C143270","display" : "Alkalosis"},{"code" : "C57118","display" : "Anorexia"},{"code" : "C57787","display" : "Dehydration"},{"code" : "C143519","display" : "Glucose intolerance"},{"code" : "C143551","display" : "Hypercalcemia"},{"code" : "C143552","display" : "Hyperglycemia"},{"code" : "C143554","display" : "Hyperkalemia"},{"code" : "C143221","display" : "Hyperlipidemia"},{"code" : "C143555","display" : "Hypermagnesemia"},{"code" : "C143556","display" : "Hypernatremia"},{"code" : "C143222","display" : "Hyperphosphatemia"},{"code" : "C143562","display" : "Hypertriglyceridemia"},{"code" : "C143563","display" : "Hyperuricemia"},{"code" : "C143564","display" : "Hypoalbuminemia"},{"code" : "C143565","display" : "Hypocalcemia"},{"code" : "C143567","display" : "Hypoglycemia"},{"code" : "C143569","display" : "Hypokalemia"},{"code" : "C143570","display" : "Hypomagnesemia"},{"code" : "C143571","display" : "Hyponatremia"},{"code" : "C143573","display" : "Hypophosphatemia"},{"code" : "C55993","display" : "Iron overload"},{"code" : "C143672","display" : "Metabolism and nutrition disorders - Other, specify"},{"code" : "C55334","display" : "Obesity"},{"code" : "C146688","display" : "Tumor lysis syndrome"},{"code" : "C143256","display" : "Abdominal soft tissue necrosis"},{"code" : "C143298","display" : "Arthralgia"},{"code" : "C143299","display" : "Arthritis"},{"code" : "C143311","display" : "Avascular necrosis"},{"code" : "C146739","display" : "Back pain"},{"code" : "C146741","display" : "Bone pain"},{"code" : "C146744","display" : "Buttock pain"},{"code" : "C143223","display" : "Chest wall necrosis"},{"code" : "C146743","display" : "Chest wall pain"},{"code" : "C146749","display" : "Exostosis"},{"code" : "C143487","display" : "Fibrosis deep connective tissue"},{"code" : "C143488","display" : "Flank pain"},{"code" : "C143514","display" : "Generalized muscle weakness"},{"code" : "C143522","display" : "Growth suppression"},{"code" : "C58383","display" : "Head soft tissue necrosis"},{"code" : "C146760","display" : "Joint effusion"},{"code" : "C143627","display" : "Joint range of motion decreased cervical spine"},{"code" : "C143628","display" : "Joint range of motion decreased lumbar spine"},{"code" : "C143629","display" : "Joint range of motion decreased"},{"code" : "C143633","display" : "Kyphosis"},{"code" : "C143655","display" : "Lordosis"},{"code" : "C143224","display" : "Muscle cramp"},{"code" : "C143682","display" : "Muscle weakness lower limb"},{"code" : "C143684","display" : "Muscle weakness trunk"},{"code" : "C143685","display" : "Muscle weakness upper limb"},{"code" : "C143686","display" : "Musculoskeletal and connective tissue disorder - Other, specify"},{"code" : "C143687","display" : "Musculoskeletal deformity"},{"code" : "C143688","display" : "Myalgia"},{"code" : "C146787","display" : "Myositis"},{"code" : "C146766","display" : "Neck pain"},{"code" : "C58394","display" : "Neck soft tissue 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"C143387","display" : "Corneal ulcer"},{"code" : "C143410","display" : "Dry eye"},{"code" : "C143466","display" : "Extraocular muscle paresis"},{"code" : "C143468","display" : "Eye disorders - Other, specify"},{"code" : "C146751","display" : "Eye pain"},{"code" : "C143471","display" : "Eyelid function disorder"},{"code" : "C143489","display" : "Flashing lights"},{"code" : "C143491","display" : "Floaters"},{"code" : "C55842","display" : "Glaucoma"},{"code" : "C55847","display" : "Keratitis"},{"code" : "C143705","display" : "Night blindness"},{"code" : "C143714","display" : "Optic nerve disorder"},{"code" : "C143734","display" : "Papilledema"},{"code" : "C143747","display" : "Periorbital edema"},{"code" : "C146770","display" : "Photophobia"},{"code" : "C146729","display" : "Retinal detachment"},{"code" : "C143814","display" : "Retinal tear"},{"code" : "C143815","display" : "Retinal vascular disorder"},{"code" : "C55891","display" : "Retinopathy"},{"code" : "C143823","display" : "Scleral disorder"},{"code" : "C55901","display" : "Uveitis"},{"code" : "C143196","display" : "Vision decreased"},{"code" : "C146677","display" : "Vitreous hemorrhage"},{"code" : "C143944","display" : "Watering eyes"},{"code" : "C143253","display" : "Abdominal distension"},{"code" : "C143255","display" : "Abdominal pain"},{"code" : "C143197","display" : "Anal fissure"},{"code" : "C143275","display" : "Anal fistula"},{"code" : "C143276","display" : "Anal hemorrhage"},{"code" : "C143277","display" : "Anal mucositis"},{"code" : "C143278","display" : "Anal necrosis"},{"code" : "C143279","display" : "Anal pain"},{"code" : "C143280","display" : "Anal stenosis"},{"code" : "C143281","display" : "Anal ulcer"},{"code" : "C143300","display" : "Ascites"},{"code" : "C143198","display" : "Belching"},{"code" : "C143322","display" : "Bloating"},{"code" : "C143358","display" : "Cecal hemorrhage"},{"code" : "C57901","display" : "Cheilitis"},{"code" : "C146788","display" : "Cholecystitis"},{"code" : "C143199","display" : "Chylous ascites"},{"code" : "C57134","display" : "Colitis"},{"code" : "C143373","display" : "Colonic fistula"},{"code" : "C143374","display" : "Colonic hemorrhage"},{"code" : "C143375","display" : "Colonic obstruction"},{"code" : "C143376","display" : "Colonic perforation"},{"code" : "C143377","display" : "Colonic stenosis"},{"code" : "C143378","display" : "Colonic ulcer"},{"code" : "C57141","display" : "Constipation"},{"code" : "C143402","display" : "Dental caries"},{"code" : "C57788","display" : "Diarrhea"},{"code" : "C143411","display" : "Dry mouth"},{"code" : "C143414","display" : "Duodenal hemorrhage"},{"code" : "C143416","display" : "Duodenal obstruction"},{"code" : "C143417","display" : "Duodenal perforation"},{"code" : "C143418","display" : "Duodenal stenosis"},{"code" : "C143419","display" : "Duodenal ulcer"},{"code" : "C57789","display" : "Duodenal fistula"},{"code" : "C143425","display" : "Dyspepsia"},{"code" : "C57795","display" : "Dysphagia"},{"code" : "C143445","display" : "Enterocolitis"},{"code" : "C143446","display" : "Enterovesical fistula"},{"code" : "C143453","display" : "Esophageal hemorrhage"},{"code" : "C143455","display" : "Esophageal necrosis"},{"code" : "C143456","display" : "Esophageal obstruction"},{"code" : "C143457","display" : "Esophageal pain"},{"code" : "C143458","display" : "Esophageal perforation"},{"code" : "C143459","display" : "Esophageal stenosis"},{"code" : "C143460","display" : "Esophageal ulcer"},{"code" : "C146710","display" : "Esophageal varices hemorrhage"},{"code" : "C57797","display" : "Esophagitis"},{"code" : "C57798","display" : "Esophageal fistula"},{"code" : "C143482","display" : "Fecal incontinence"},{"code" : "C57807","display" : "Flatulence"},{"code" : "C143499","display" : "Gastric fistula"},{"code" : "C143500","display" : "Gastric hemorrhage"},{"code" : "C143501","display" : "Gastric necrosis"},{"code" : "C143502","display" : "Gastric perforation"},{"code" : "C143503","display" : "Gastric stenosis"},{"code" : "C143504","display" : "Gastric ulcer"},{"code" : "C57812","display" : "Gastritis"},{"code" : "C143506","display" : "Gastroesophageal reflux disease"},{"code" : "C143508","display" : "Gastrointestinal disorders - Other, specify"},{"code" : "C146637","display" : "Gastrointestinal fistula"},{"code" : "C57814","display" : "Ileus"},{"code" : "C143510","display" : "Gastrointestinal pain"},{"code" : "C143512","display" : "Gastroparesis"},{"code" : "C146626","display" : "Gingival pain"},{"code" : "C143537","display" : "Hemorrhoidal hemorrhage"},{"code" : "C146738","display" : "Hemorrhoids"},{"code" : "C146633","display" : "Ileal perforation"},{"code" : "C143578","display" : "Ileal stenosis"},{"code" : "C57821","display" : "Ileal fistula"},{"code" : "C56542","display" : "Ileal hemorrhage"},{"code" : "C57823","display" : "Ileal obstruction"},{"code" : "C57826","display" : "Ileal ulcer"},{"code" : "C143595","display" : "Intra-abdominal hemorrhage"},{"code" : "C143622","display" : "Jejunal perforation"},{"code" : "C143623","display" : "Jejunal stenosis"},{"code" : "C57827","display" : "Jejunal fistula"},{"code" : "C56543","display" : "Jejunal hemorrhage"},{"code" : "C57829","display" : "Jejunal obstruction"},{"code" : "C57832","display" : "Jejunal ulcer"},{"code" : "C146761","display" : "Lip pain"},{"code" : "C143656","display" : "Lower gastrointestinal hemorrhage"},{"code" : "C57838","display" : "Malabsorption"},{"code" : "C143679","display" : "Mucositis oral"},{"code" : "C146764","display" : "Nausea"},{"code" : "C143710","display" : "Obstruction gastric"},{"code" : "C143715","display" : "Oral cavity fistula"},{"code" : "C56551","display" : "Oral hemorrhage"},{"code" : "C143716","display" : "Oral dysesthesia"},{"code" : "C146627","display" : "Oral pain"},{"code" : "C57845","display" : "Pancreatic fistula"},{"code" : "C56554","display" : "Pancreatic hemorrhage"},{"code" : "C143730","display" : "Pancreatic duct stenosis"},{"code" : "C143732","display" : "Pancreatic necrosis"},{"code" : "C146789","display" : "Pancreatitis"},{"code" : "C57849","display" : "Periodontal disease"},{"code" : "C57850","display" : "Peritoneal necrosis"},{"code" : "C57857","display" : "Proctitis"},{"code" : "C143200","display" : "Rectal fissure"},{"code" : "C143802","display" : "Rectal mucositis"},{"code" : "C146631","display" : "Rectal pain"},{"code" : "C146634","display" : "Rectal perforation"},{"code" : "C143803","display" : "Rectal stenosis"},{"code" : "C57859","display" : "Rectal fistula"},{"code" : "C56560","display" : "Rectal hemorrhage"},{"code" : "C57863","display" : "Rectal necrosis"},{"code" : "C57864","display" : "Rectal obstruction"},{"code" : "C57867","display" : "Rectal ulcer"},{"code" : "C146632","display" : "Retroperitoneal hemorrhage"},{"code" : "C143821","display" : "Salivary duct inflammation"},{"code" : "C57868","display" : "Salivary gland fistula"},{"code" : "C143842","display" : "Small intestinal mucositis"},{"code" : "C143843","display" : "Small intestinal obstruction"},{"code" : "C146635","display" : "Small intestinal perforation"},{"code" : "C143844","display" : "Small intestinal stenosis"},{"code" : "C143846","display" : "Small intestine ulcer"},{"code" : "C146774","display" : "Stomach pain"},{"code" : "C143876","display" : "Tooth development disorder"},{"code" : "C143877","display" : "Tooth discoloration"},{"code" : "C143879","display" : "Toothache"},{"code" : "C146730","display" : "Typhlitis"},{"code" : "C143895","display" : "Upper gastrointestinal hemorrhage"},{"code" : "C143938","display" : "Visceral arterial ischemia"},{"code" : "C57896","display" : "Vomiting"},{"code" : "C143366","display" : "Chills"},{"code" : "C143395","display" : "Death neonatal"},{"code" : "C143396","display" : "Death NOS"},{"code" : "C143201","display" : "Disease progression"},{"code" : "C143432","display" : "Edema face"},{"code" : "C143433","display" : "Edema limbs"},{"code" : "C143434","display" : "Edema trunk"},{"code" : "C143474","display" : "Facial pain"},{"code" : "C146753","display" : "Fatigue"},{"code" : "C143485","display" : "Fever"},{"code" : "C143492","display" : "Flu like symptoms"},{"code" : "C143496","display" : "Gait disturbance"},{"code" : "C143513","display" : "General disorders and administration site conditions - Other, specify"},{"code" : "C143202","display" : "Generalized edema"},{"code" : "C55332","display" : "Hypothermia"},{"code" : "C143584","display" : "Infusion site extravasation"},{"code" : "C143585","display" : "Injection site reaction"},{"code" : "C143654","display" : "Localized edema"},{"code" : "C143665","display" : "Malaise"},{"code" : "C143680","display" : "Multi-organ failure"},{"code" : "C143700","display" : "Neck edema"},{"code" : "C143707","display" : "Non-cardiac chest pain"},{"code" : "C143725","display" : "Pain"},{"code" : "C143863","display" : "Sudden death NOS"},{"code" : "C143203","display" : "Vaccination site lymphadenopathy"},{"code" : "C143314","display" : "Bile duct stenosis"},{"code" : "C143316","display" : "Biliary fistula"},{"code" : "C143204","display" : "Budd-Chiari syndrome"},{"code" : "C57808","display" : "Gallbladder fistula"},{"code" : "C146735","display" : "Gallbladder necrosis"},{"code" : "C57810","display" : "Gallbladder obstruction"},{"code" : "C146755","display" : "Gallbladder pain"},{"code" : "C146708","display" : "Gallbladder perforation"},{"code" : "C143539","display" : "Hepatic failure"},{"code" : "C143540","display" : "Hepatic hemorrhage"},{"code" : "C146736","display" : "Hepatic necrosis"},{"code" : "C143542","display" : "Hepatic pain"},{"code" : "C143544","display" : "Hepatobiliary disorders - Other, specify"},{"code" : "C143742","display" : "Perforation bile duct"},{"code" : "C143769","display" : "Portal hypertension"},{"code" : "C143770","display" : "Portal vein thrombosis"},{"code" : "C143205","display" : "Sinusoidal obstruction syndrome"},{"code" : "C143271","display" : "Allergic reaction"},{"code" : "C143282","display" : "Anaphylaxis"},{"code" : "C143310","display" : "Autoimmune disorder"},{"code" : "C143394","display" : "Cytokine release syndrome"},{"code" : "C143580","display" : "Immune system disorders - Other, specify"},{"code" : "C146642","display" : "Serum sickness"},{"code" : "C143254","display" : "Abdominal infection"},{"code" : "C143285","display" : "Anorectal infection"},{"code" : "C143293","display" : "Appendicitis perforated"},{"code" : "C143294","display" : "Appendicitis"},{"code" : "C143297","display" : "Arteritis infective"},{"code" : "C143206","display" : "Bacteremia"},{"code" : "C143317","display" : "Biliary tract infection"},{"code" : "C143319","display" : "Bladder infection"},{"code" : "C143331","display" : "Bone infection"},{"code" : "C143336","display" : "Breast infection"},{"code" : "C143339","display" : "Bronchial infection"},{"code" : "C143356","display" : "Catheter related infection"},{"code" : "C143359","display" : "Cecal infection"},{"code" : "C143362","display" : "Cervicitis infection"},{"code" : "C143383","display" : "Conjunctivitis infective"},{"code" : "C143384","display" : "Conjunctivitis"},{"code" : "C143386","display" : "Corneal infection"},{"code" : "C143390","display" : "Cranial nerve infection"},{"code" : "C143207","display" : "Cytomegalovirus infection reactivation"},{"code" : "C143406","display" : "Device related infection"},{"code" : "C143415","display" : "Duodenal infection"},{"code" : "C143438","display" : "Encephalitis infection"},{"code" : "C143439","display" : "Encephalomyelitis infection"},{"code" : "C143441","display" : "Endocarditis infective"},{"code" : "C143443","display" : "Endophthalmitis"},{"code" : "C143444","display" : "Enterocolitis infectious"},{"code" : "C143208","display" : "Epstein-Barr virus infection reactivation"},{"code" : "C143454","display" : "Esophageal infection"},{"code" : "C143469","display" : "Eye infection"},{"code" : "C143209","display" : "Folliculitis"},{"code" : "C143210","display" : "Fungemia"},{"code" : "C143497","display" : "Gallbladder infection"},{"code" : "C143523","display" : "Gum infection"},{"code" : "C143541","display" : "Hepatic infection"},{"code" : "C143211","display" : "Hepatitis B reactivation"},{"code" : "C143543","display" : "Hepatitis viral"},{"code" : "C143212","display" : "Herpes simplex reactivation"},{"code" : "C143581","display" : "Infections and infestations - Other, specify"},{"code" : "C143582","display" : "Infective myositis"},{"code" : "C143626","display" : "Joint infection"},{"code" : "C143632","display" : "Kidney infection"},{"code" : "C143641","display" : "Laryngitis"},{"code" : "C143651","display" : "Lip infection"},{"code" : "C143657","display" : "Lung infection"},{"code" : "C143658","display" : "Lymph gland infection"},{"code" : "C143667","display" : "Mediastinal infection"},{"code" : "C143670","display" : "Meningitis"},{"code" : "C143678","display" : "Mucosal infection"},{"code" : "C55459","display" : "Myelitis"},{"code" : "C143695","display" : "Nail infection"},{"code" : "C143719","display" : "Otitis externa"},{"code" : "C143720","display" : "Otitis media"},{"code" : "C143721","display" : "Ovarian infection"},{"code" : "C143728","display" : "Pancreas infection"},{"code" : "C143735","display" : "Papulopustular rash"},{"code" : "C143737","display" : "Paronychia"},{"code" : "C143740","display" : "Pelvic infection"},{"code" : "C143741","display" : "Penile infection"},{"code" : "C143748","display" : "Periorbital infection"},{"code" : "C143751","display" : "Peripheral nerve infection"},{"code" : "C143753","display" : "Peritoneal infection"},{"code" : "C143758","display" : "Pharyngitis"},{"code" : "C143760","display" : "Phlebitis infective"},{"code" : "C143766","display" : "Pleural infection"},{"code" : "C143783","display" : "Prostate infection"},{"code" : "C143800","display" : "Rash pustular"},{"code" : "C143819","display" : "Rhinitis infective"},{"code" : "C143822","display" : "Salivary gland infection"},{"code" : "C143825","display" : "Scrotal infection"},{"code" : "C143827","display" : "Sepsis"},{"code" : "C143213","display" : "Shingles"},{"code" : "C143832","display" : "Sinusitis"},{"code" : "C143838","display" : "Skin infection"},{"code" : "C143845","display" : "Small intestine infection"},{"code" : "C143849","display" : "Soft tissue infection"},{"code" : "C143857","display" : "Splenic infection"},{"code" : "C143860","display" : "Stoma site infection"},{"code" : "C143214","display" : "Thrush"},{"code" : "C143878","display" : "Tooth infection"},{"code" : "C143884","display" : "Tracheitis"},{"code" : "C143896","display" : "Upper respiratory infection"},{"code" : "C143899","display" : "Urethral infection"},{"code" : "C143904","display" : "Urinary tract infection"},{"code" : "C143917","display" : "Uterine infection"},{"code" : "C143924","display" : "Vaginal infection"},{"code" : "C143215","display" : "Viremia"},{"code" : "C143943","display" : "Vulval infection"},{"code" : "C143951","display" : "Wound infection"},{"code" : "C143284","display" : "Ankle fracture"},{"code" : "C143289","display" : "Aortic injury"},{"code" : "C143296","display" : "Arterial injury"},{"code" : "C143315","display" : "Biliary anastomotic leak"},{"code" : "C143318","display" : "Bladder anastomotic leak"},{"code" : "C143345","display" : "Bruising"},{"code" : "C57900","display" : "Burn"},{"code" : "C143405","display" : "Dermatitis radiation"},{"code" : "C143451","display" : "Esophageal anastomotic leak"},{"code" : "C143475","display" : "Fall"},{"code" : "C143476","display" : "Fallopian tube anastomotic leak"},{"code" : "C146714","display" : "Fallopian tube perforation"},{"code" : "C58382","display" : "Fracture"},{"code" : "C143498","display" : "Gastric anastomotic leak"},{"code" : "C143507","display" : "Gastrointestinal anastomotic leak"},{"code" : "C143511","display" : "Gastrointestinal stoma necrosis"},{"code" : "C143546","display" : "Hip fracture"},{"code" : "C56735","display" : "Injury to inferior vena cava"},{"code" : "C143583","display" : "Infusion related reaction"},{"code" : "C143586","display" : "Injury to carotid artery"},{"code" : "C143587","display" : "Injury to jugular vein"},{"code" : "C143588","display" : "Injury to superior vena cava"},{"code" : "C143589","display" : "Injury, poisoning and procedural complications - Other, specify"},{"code" : "C143592","display" : "Intestinal stoma leak"},{"code" : "C143593","display" : "Intestinal stoma obstruction"},{"code" : "C143594","display" : "Intestinal stoma site bleeding"},{"code" : "C143597","display" : "Intraoperative arterial injury"},{"code" : "C143598","display" : "Intraoperative breast injury"},{"code" : "C143599","display" : "Intraoperative cardiac injury"},{"code" : "C143600","display" : "Intraoperative ear injury"},{"code" : "C143601","display" : "Intraoperative endocrine injury"},{"code" : "C143602","display" : "Intraoperative 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bleeding"},{"code" : "C143897","display" : "Ureteric anastomotic leak"},{"code" : "C143898","display" : "Urethral anastomotic leak"},{"code" : "C143910","display" : "Urostomy leak"},{"code" : "C143911","display" : "Urostomy obstruction"},{"code" : "C143912","display" : "Urostomy site bleeding"},{"code" : "C143913","display" : "Urostomy stenosis"},{"code" : "C143915","display" : "Uterine anastomotic leak"},{"code" : "C143919","display" : "Uterine perforation"},{"code" : "C143216","display" : "Vaccination complication"},{"code" : "C143921","display" : "Vaginal anastomotic leak"},{"code" : "C143928","display" : "Vas deferens anastomotic leak"},{"code" : "C143929","display" : "Vascular access complication"},{"code" : "C143933","display" : "Venous injury"},{"code" : "C143949","display" : "Wound complication"},{"code" : "C143950","display" : "Wound dehiscence"},{"code" : "C143952","display" : "Wrist fracture"},{"code" : "C143261","display" : "Activated partial thromboplastin time 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NOS"},{"code" : "C143266","display" : "Akathisia"},{"code" : "C143274","display" : "Amnesia"},{"code" : "C143230","display" : "Anosmia"},{"code" : "C143291","display" : "Aphonia"},{"code" : "C143295","display" : "Arachnoiditis"},{"code" : "C146737","display" : "Ataxia"},{"code" : "C146754","display" : "Brachial plexopathy"},{"code" : "C143360","display" : "Central nervous system necrosis"},{"code" : "C143361","display" : "Cerebrospinal fluid leakage"},{"code" : "C146746","display" : "Cognitive disturbance"},{"code" : "C143379","display" : "Concentration impairment"},{"code" : "C143403","display" : "Depressed level of consciousness"},{"code" : "C146747","display" : "Dizziness"},{"code" : "C143420","display" : "Dysarthria"},{"code" : "C143421","display" : "Dysesthesia"},{"code" : "C143422","display" : "Dysgeusia"},{"code" : "C143427","display" : "Dysphasia"},{"code" : "C143431","display" : "Edema cerebral"},{"code" : "C146699","display" : "Encephalopathy"},{"code" : "C143467","display" : 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#237

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"VN-61","display" : "Hải Dương","property" : [{"code" : "country","valueString" : "Viet Nam"},{"code" : "subdivisionType","valueString" : "Province"},{"code" : "countryCode","valueString" : "VN"}]},{"code" : "VN-63","display" : "Hà Nam","property" : [{"code" : "country","valueString" : "Viet Nam"},{"code" : "subdivisionType","valueString" : "Province"},{"code" : "countryCode","valueString" : "VN"}]},{"code" : "VN-66","display" : "Hưng Yên","property" : [{"code" : "country","valueString" : "Viet Nam"},{"code" : "subdivisionType","valueString" : "Province"},{"code" : "countryCode","valueString" : "VN"}]},{"code" : "VN-67","display" : "Nam Ðịnh","property" : [{"code" : "country","valueString" : "Viet Nam"},{"code" : "subdivisionType","valueString" : "Province"},{"code" : "countryCode","valueString" : "VN"}]},{"code" : "VN-68","display" : "Phú Thọ","property" : [{"code" : "country","valueString" : "Viet Nam"},{"code" : "subdivisionType","valueString" : "Province"},{"code" : 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: "country","valueString" : "Viet Nam"},{"code" : "subdivisionType","valueString" : "Municipality"},{"code" : "countryCode","valueString" : "VN"}]},{"code" : "VG-VG","display" : "Virgin Islands","property" : [{"code" : "country","valueString" : "Virgin Islands"},{"code" : "subdivisionType","valueString" : "Country"},{"code" : "countryCode","valueString" : "VG"}]},{"code" : "VI-VI","display" : "Virgin Islands","property" : [{"code" : "country","valueString" : "Virgin Islands"},{"code" : "subdivisionType","valueString" : "Country"},{"code" : "countryCode","valueString" : "VI"}]},{"code" : "WF-WF","display" : "Wallis & Futuna Islands","property" : [{"code" : "country","valueString" : "Wallis & Futuna Islands"},{"code" : "subdivisionType","valueString" : "Country"},{"code" : "countryCode","valueString" : "WF"}]},{"code" : "EH-EH","display" : "Western Sahara","property" : [{"code" : "country","valueString" : "Western Sahara"},{"code" : "subdivisionType","valueString" : "Country"},{"code" : 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"subdivisionType","valueString" : "Governorate"},{"code" : "countryCode","valueString" : "YE"}]},{"code" : "YE-JA","display" : "Al Jawf","property" : [{"code" : "country","valueString" : "Yemen"},{"code" : "subdivisionType","valueString" : "Governorate"},{"code" : "countryCode","valueString" : "YE"}]},{"code" : "YE-LA","display" : "Laḩij","property" : [{"code" : "country","valueString" : "Yemen"},{"code" : "subdivisionType","valueString" : "Governorate"},{"code" : "countryCode","valueString" : "YE"}]},{"code" : "YE-MA","display" : "Ma'rib","property" : [{"code" : "country","valueString" : "Yemen"},{"code" : "subdivisionType","valueString" : "Governorate"},{"code" : "countryCode","valueString" : "YE"}]},{"code" : "YE-MR","display" : "Al Mahrah","property" : [{"code" : "country","valueString" : "Yemen"},{"code" : "subdivisionType","valueString" : "Governorate"},{"code" : "countryCode","valueString" : "YE"}]},{"code" : "YE-MW","display" : "Al Maḩwīt","property" : [{"code" : "country","valueString" : "Yemen"},{"code" : "subdivisionType","valueString" : "Governorate"},{"code" : "countryCode","valueString" : "YE"}]},{"code" : "YE-RA","display" : "Raymah","property" : [{"code" : "country","valueString" : "Yemen"},{"code" : "subdivisionType","valueString" : "Governorate"},{"code" : "countryCode","valueString" : "YE"}]},{"code" : "YE-SA","display" : "Amānat al ‘Āşimah","property" : [{"code" : "country","valueString" : "Yemen"},{"code" : "subdivisionType","valueString" : "Municipality"},{"code" : "countryCode","valueString" : "YE"}]},{"code" : "YE-SD","display" : "Şāʻdah","property" : [{"code" : "country","valueString" : "Yemen"},{"code" : "subdivisionType","valueString" : "Governorate"},{"code" : "countryCode","valueString" : "YE"}]},{"code" : "YE-SH","display" : "Shabwah","property" : [{"code" : "country","valueString" : "Yemen"},{"code" : "subdivisionType","valueString" : "Governorate"},{"code" : "countryCode","valueString" : "YE"}]},{"code" : 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"subdivisionType","valueString" : "Province"},{"code" : "countryCode","valueString" : "ZM"}]},{"code" : "ZM-09","display" : "Lusaka","property" : [{"code" : "country","valueString" : "Zambia"},{"code" : "subdivisionType","valueString" : "Province"},{"code" : "countryCode","valueString" : "ZM"}]},{"code" : "ZM-10","display" : "Muchinga","property" : [{"code" : "country","valueString" : "Zambia"},{"code" : "subdivisionType","valueString" : "Province"},{"code" : "countryCode","valueString" : "ZM"}]},{"code" : "ZW-BU","display" : "Bulawayo","property" : [{"code" : "country","valueString" : "Zimbabwe"},{"code" : "subdivisionType","valueString" : "Province"},{"code" : "countryCode","valueString" : "ZW"}]},{"code" : "ZW-HA","display" : "Harare","property" : [{"code" : "country","valueString" : "Zimbabwe"},{"code" : "subdivisionType","valueString" : "Province"},{"code" : "countryCode","valueString" : "ZW"}]},{"code" : "ZW-MA","display" : "Manicaland","property" : [{"code" : 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#240

GET https://tx.fhir.org/r4/CodeSystem?_format=json&url=http%3A%2F%2Funstats.un.org%2Funsd%2Fmethods%2Fm49%2Fm49.htm HTTP/1.0
User-Agent: hapi-fhir-tooling-client
Accept: application/fhir+json; fhirVersion=4.0

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:264
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:28:24 GMT
pragma:no-cache
server:nginx
x-request-id:253-23569069

{"resourceType" : "Bundle","id" : "8df425c3-a852-4bf7-b6c0-b50b1f4f18","meta" : {"lastUpdated" : "2026-01-30T18:28:24.162Z"},"type" : "searchset","total" : 0,"link" : [{"relation" : "self","url" : "CodeSystem?&url=http://unstats.un.org/unsd/methods/m49/m49.htm"}]}

#241

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:801
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:28:24 GMT
last-modified:Fri, 30 Jan 2026 18:28:24 GMT
pragma:no-cache
server:nginx
x-request-id:253-23569073

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://unstats.un.org/unsd/methods/m49/m49.htm"},{"name" : "code","valueCode" : "001"},{"name" : "display","valueString" : "World"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://unstats.un.org/unsd/methods/m49/m49.htm#001 (\"World\")]\"\r\n0 0     : 0ms  : Check \"http://unstats.un.org/unsd/methods/m49/m49.htm#001\"\r\n0 0     : 0ms  : Using CodeSystem \"http://unstats.un.org/unsd/methods/m49/m49.htm|\" (content = complete)\r\n"}]}

#242

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/ValueSet/jurisdiction--2","version":"4.0.1","status":"active","compose":{"include":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","filter":[{"property":"class","op":"=","value":"region"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1212
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:28:24 GMT
last-modified:Fri, 30 Jan 2026 18:28:24 GMT
pragma:no-cache
server:nginx
x-request-id:253-23569077

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://unstats.un.org/unsd/methods/m49/m49.htm"},{"name" : "code","valueCode" : "001"},{"name" : "display","valueString" : "World"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/jurisdiction--2|4.0.1 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://unstats.un.org/unsd/methods/m49/m49.htm)(class=region)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://unstats.un.org/unsd/methods/m49/m49.htm|\"\r\n0 0     : 0ms  : Validate \"[http://unstats.un.org/unsd/methods/m49/m49.htm#001 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://unstats.un.org/unsd/methods/m49/m49.htm#001\"\r\n0 0     : 0ms  : CodeSystem found: http://unstats.un.org/unsd/methods/m49/m49.htm| for http://unstats.un.org/unsd/methods/m49/m49.htm\r\n0 0     : 0ms  : check code in (http://unstats.un.org/unsd/methods/m49/m49.htm)(class=region) at Coding\r\n0 0     : 0ms  : Filter \"class=region\": Code \"001\" found in http://unstats.un.org/unsd/methods/m49/m49.htm|\r\n"}]}

#243

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0002072"}},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:28:25 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:ae078651-c846-4e90-bd86-d59af27d7639
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:ae078651-c846-4e90-bd86-d59af27d7639
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0002072"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#244

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001536"}},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:28:26 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:38790b3e-cc4e-4fc9-b2e6-7e5a8d50a744
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:38790b3e-cc4e-4fc9-b2e6-7e5a8d50a744
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001536"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#245

GET https://tx.fhir.org/r4/ValueSet?_format=json&url=http%3A%2F%2Floinc.org HTTP/1.0
User-Agent: hapi-fhir-tooling-client
Accept: application/fhir+json; fhirVersion=4.0

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:232
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:28:26 GMT
pragma:no-cache
server:nginx
x-request-id:253-23569106

{"resourceType" : "Bundle","id" : "8a77c1ea-4cb9-48a4-a84d-697d4eab72","meta" : {"lastUpdated" : "2026-01-30T18:28:26.240Z"},"type" : "searchset","total" : 0,"link" : [{"relation" : "self","url" : "ValueSet?&url=http://loinc.org"}]}

#246

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA10315-2","display":"Ultrarapid metabolizer"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"mode","valueString":"lenient-display-validation"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:802
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:28:26 GMT
last-modified:Fri, 30 Jan 2026 18:28:26 GMT
pragma:no-cache
server:nginx
x-request-id:253-23569109

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA10315-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Ultrarapid metabolizer"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest, display-warning\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA10315-2 (\"Ultrarapid metabolizer\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA10315-2\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#247

POST https://tx.fhir.org/r4/ValueSet/$batch-validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA25391-6","display":"Normal metabolizer"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA25390-8","display":"Rapid metabolizer"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA10317-8","display":"Intermediate metabolizer"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA9657-3","display":"Poor metabolizer"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA19542-2","display":"Low Risk"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA19541-4","display":"High Risk"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA6676-6","display":"Resistant"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA6677-4","display":"Responsive"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA9660-7","display":"Presumed resistant"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA9661-5","display":"Presumed responsive"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, 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en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA6674-1","display":"Presumed Benign"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA9662-3","display":"Presumed non-responsive"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA25392-4","display":"Increased function"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA25393-2","display":"Normal function"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA25395-7","display":"Decreased function"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA25394-0","display":"Poor function"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true}]}}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:5840
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:28:26 GMT
last-modified:Fri, 30 Jan 2026 18:28:26 GMT
pragma:no-cache
server:nginx
x-request-id:253-23569110

{"resourceType" : "Parameters","parameter" : [{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA25391-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Normal metabolizer"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA25390-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Rapid metabolizer"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA10317-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Intermediate metabolizer"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA9657-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Poor metabolizer"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA19542-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Low risk"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA19541-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "High risk"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6676-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Resistant"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6677-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Responsive"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA9660-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Presumed resistant"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA9661-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Presumed responsive"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6682-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Unknown Significance"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6675-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Benign"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6674-1"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Presumed Benign"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA9662-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Presumed non-responsive"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA25392-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Increased function"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA25393-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Normal function"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA25395-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Decreased function"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA25394-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Poor function"}]}}]}

#248

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://snomed.info/sct","code":"444734003","display":"Does not meet eligibility criteria for clinical trial (finding)"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"mode","valueString":"lenient-display-validation"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-expose-headers:Content-Location, Location
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connection:keep-alive
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content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:28:26 GMT
last-modified:Fri, 30 Jan 2026 18:28:26 GMT
pragma:no-cache
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x-request-id:253-23569114

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "444734003"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Does not meet eligibility criteria for clinical trial (finding)"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest, display-warning\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://snomed.info/sct#444734003 (\"Does not meet eligibility criteria for clinical trial (finding)\")]\"\r\n0 0     : 0ms  : Check \"http://snomed.info/sct#444734003\"\r\n0 0     : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#249

POST https://tx.fhir.org/r4/ValueSet/$batch-validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://snomed.info/sct","code":"399223003","display":"Patient eligible for clinical trial (finding)"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true}]}}]}

200
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date:Fri, 30 Jan 2026 18:28:26 GMT
last-modified:Fri, 30 Jan 2026 18:28:26 GMT
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x-request-id:253-23569117

{"resourceType" : "Parameters","parameter" : [{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "399223003"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Patient eligible for clinical trial (finding)"}]}}]}

#250

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0002072"}},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"diagnostics","valueBoolean":true}]}

200
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date:Fri, 30 Jan 2026 18:28:27 GMT
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#251

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001060"}},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"diagnostics","valueBoolean":true}]}

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x-request-id:73f585ad-4a3e-4c03-9166-9a616ff20b21
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#252

GET https://tx.fhir.org/r4/ValueSet?_format=json&url=http%3A%2F%2Fvarnomen.hgvs.org HTTP/1.0
User-Agent: hapi-fhir-tooling-client
Accept: application/fhir+json; fhirVersion=4.0

200
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content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:28:28 GMT
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x-request-id:253-23569136

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#253

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"85337-4","display":"Estrogen receptor Ag [Presence] in Breast cancer specimen by Immune stain"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"mode","valueString":"lenient-display-validation"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:28:28 GMT
last-modified:Fri, 30 Jan 2026 18:28:28 GMT
pragma:no-cache
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x-request-id:253-23569141

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#254

POST https://tx.fhir.org/r4/ValueSet/$batch-validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

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last-modified:Fri, 30 Jan 2026 18:28:28 GMT
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"display","valueString" : "Microsatellite instability marker D17S250 in Cancer specimen Qualitative"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "94077-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Tumor mutation burden [Interpretation]"}]}}]}

#255

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001537"}},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"diagnostics","valueBoolean":true}]}

200
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date:Fri, 30 Jan 2026 18:28:28 GMT
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x-request-id:0d56260c-4a96-49d4-bb8e-611389c6c6b7
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001537"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#256

POST https://tx.fhir.org/r4/ValueSet/$batch-validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

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en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA6686-5"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:1000035"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, 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last-modified:Fri, 30 Jan 2026 18:28:29 GMT
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"message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}}]}}]}

#257

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"93044-6"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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cache-control:public, max-age=600
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date:Fri, 30 Jan 2026 18:28:35 GMT
last-modified:Fri, 30 Jan 2026 18:28:35 GMT
pragma:no-cache
server:nginx
x-request-id:253-23569219

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "93044-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Level of evidence"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "93044-6"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#93044-6 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#93044-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#258

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

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date:Fri, 30 Jan 2026 18:28:36 GMT
last-modified:Fri, 30 Jan 2026 18:28:36 GMT
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server:nginx
x-request-id:253-23569244

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "53037-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic variation clinical significance [Imp]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "53037-8"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#53037-8 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#53037-8\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#259

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81259-4"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:871
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:28:38 GMT
last-modified:Fri, 30 Jan 2026 18:28:38 GMT
pragma:no-cache
server:nginx
x-request-id:253-23569278

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81259-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Associated phenotype"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81259-4"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81259-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81259-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#260

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"5792-7"}},{"name":"valueset-membership-only","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL4034-6"}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1261
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:28:38 GMT
last-modified:Fri, 30 Jan 2026 18:28:38 GMT
pragma:no-cache
server:nginx
x-request-id:253-23569307

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "5792-7"},{"name" : "message","valueString" : "The provided code 'http://loinc.org#5792-7' was not found in the value set 'http://loinc.org/vs/LL4034-6'"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "The provided code 'http://loinc.org#5792-7' was not found in the value set 'http://loinc.org/vs/LL4034-6'"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL4034-6 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, membership-only, default-to-latest\r\n0 0     : 0ms  : Validate \"[http://loinc.org#5792-7 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#5792-7\"\r\n"}]}

#261

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48018-6"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:868
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:28:40 GMT
last-modified:Fri, 30 Jan 2026 18:28:40 GMT
pragma:no-cache
server:nginx
x-request-id:253-23569319

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48018-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Gene studied [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48018-6"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48018-6 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48018-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#262

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48001-2"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:884
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:28:40 GMT
last-modified:Fri, 30 Jan 2026 18:28:40 GMT
pragma:no-cache
server:nginx
x-request-id:253-23569349

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48001-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Cytogenetic (chromosome) location"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48001-2"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48001-2 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48001-2\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#263

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"62374-4"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:892
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:28:41 GMT
last-modified:Fri, 30 Jan 2026 18:28:41 GMT
pragma:no-cache
server:nginx
x-request-id:253-23569370

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "62374-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Human reference sequence assembly version"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "62374-4"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#62374-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#62374-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#264

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48000-4"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:922
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:28:42 GMT
last-modified:Fri, 30 Jan 2026 18:28:42 GMT
pragma:no-cache
server:nginx
x-request-id:253-23569386

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48000-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Chromosome [Identifier] in Blood or Tissue by Molecular genetics method"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48000-4"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48000-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48000-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#265

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"92821-8"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:882
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:28:44 GMT
last-modified:Fri, 30 Jan 2026 18:28:44 GMT
pragma:no-cache
server:nginx
x-request-id:253-23569412

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "92821-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic frequency in Population"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "92821-8"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#92821-8 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#92821-8\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#266

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"51969-4"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:874
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:28:47 GMT
last-modified:Fri, 30 Jan 2026 18:28:47 GMT
pragma:no-cache
server:nginx
x-request-id:253-23569451

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51969-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic analysis report"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "51969-4"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#51969-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#51969-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#267

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"84413-4"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:872
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:28:50 GMT
last-modified:Fri, 30 Jan 2026 18:28:50 GMT
pragma:no-cache
server:nginx
x-request-id:253-23569502

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "84413-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genotype display name"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "84413-4"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#84413-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#84413-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#268

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"84414-2"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:865
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:28:51 GMT
last-modified:Fri, 30 Jan 2026 18:28:51 GMT
pragma:no-cache
server:nginx
x-request-id:253-23569518

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "84414-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Haplotype name"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "84414-2"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#84414-2 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#84414-2\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#269

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48004-6"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:870
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:28:55 GMT
last-modified:Fri, 30 Jan 2026 18:28:55 GMT
pragma:no-cache
server:nginx
x-request-id:253-23569561

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48004-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "DNA change (c.HGVS)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48004-6"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48004-6 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48004-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#270

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"51958-7"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:885
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:28:56 GMT
last-modified:Fri, 30 Jan 2026 18:28:56 GMT
pragma:no-cache
server:nginx
x-request-id:253-23569584

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51958-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Transcript reference sequence [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "51958-7"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#51958-7 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#51958-7\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#271

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48005-3"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:876
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:28:58 GMT
last-modified:Fri, 30 Jan 2026 18:28:58 GMT
pragma:no-cache
server:nginx
x-request-id:253-23569605

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48005-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Amino acid change (pHGVS)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48005-3"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48005-3 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48005-3\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#272

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"82120-7"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:864
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:29:00 GMT
last-modified:Fri, 30 Jan 2026 18:29:00 GMT
pragma:no-cache
server:nginx
x-request-id:253-23569632

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82120-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic phase"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "82120-7"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#82120-7 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#82120-7\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#273

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"51963-7"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:875
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:29:02 GMT
last-modified:Fri, 30 Jan 2026 18:29:02 GMT
pragma:no-cache
server:nginx
x-request-id:253-23569668

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51963-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Medication assessed [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "51963-7"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#51963-7 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#51963-7\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#274

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"69548-6"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:877
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:29:04 GMT
last-modified:Fri, 30 Jan 2026 18:29:04 GMT
pragma:no-cache
server:nginx
x-request-id:253-23569692

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69548-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic variant assessment"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "69548-6"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#69548-6 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#69548-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#275

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81290-9"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:877
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:29:06 GMT
last-modified:Fri, 30 Jan 2026 18:29:06 GMT
pragma:no-cache
server:nginx
x-request-id:253-23569716

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81290-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic DNA change (gHGVS)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81290-9"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81290-9 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81290-9\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#276

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81291-7"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:863
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:29:07 GMT
last-modified:Fri, 30 Jan 2026 18:29:07 GMT
pragma:no-cache
server:nginx
x-request-id:253-23569738

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81291-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Variant ISCN"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81291-7"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81291-7 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81291-7\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#277

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48013-7"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:882
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:29:08 GMT
last-modified:Fri, 30 Jan 2026 18:29:08 GMT
pragma:no-cache
server:nginx
x-request-id:253-23569756

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48013-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic reference sequence [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48013-7"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48013-7 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48013-7\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#278

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81254-5"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:875
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:29:09 GMT
last-modified:Fri, 30 Jan 2026 18:29:09 GMT
pragma:no-cache
server:nginx
x-request-id:253-23569768

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81254-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic allele start-end"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81254-5"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81254-5 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81254-5\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#279

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81302-2"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:889
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:29:11 GMT
last-modified:Fri, 30 Jan 2026 18:29:11 GMT
pragma:no-cache
server:nginx
x-request-id:253-23569792

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81302-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Structural variant inner start and end"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81302-2"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81302-2 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81302-2\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#280

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81301-4"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:889
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:29:12 GMT
last-modified:Fri, 30 Jan 2026 18:29:12 GMT
pragma:no-cache
server:nginx
x-request-id:253-23569809

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81301-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Structural variant outer start and end"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81301-4"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81301-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81301-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#281

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"92822-6"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:883
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:29:14 GMT
last-modified:Fri, 30 Jan 2026 18:29:14 GMT
pragma:no-cache
server:nginx
x-request-id:253-23569831

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "92822-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic coordinate system [Type]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "92822-6"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#92822-6 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#92822-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#282

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"69547-8"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:874
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:29:15 GMT
last-modified:Fri, 30 Jan 2026 18:29:15 GMT
pragma:no-cache
server:nginx
x-request-id:253-23569849

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69547-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic ref allele [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "69547-8"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#69547-8 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#69547-8\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#283

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"69551-0"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:874
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:29:17 GMT
last-modified:Fri, 30 Jan 2026 18:29:17 GMT
pragma:no-cache
server:nginx
x-request-id:253-23569873

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69551-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic alt allele [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "69551-0"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#69551-0 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#69551-0\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#284

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48019-4"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:866
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:29:18 GMT
last-modified:Fri, 30 Jan 2026 18:29:18 GMT
pragma:no-cache
server:nginx
x-request-id:253-23569895

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48019-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "DNA change type"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48019-4"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48019-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48019-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#285

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48002-0"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:878
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:29:20 GMT
last-modified:Fri, 30 Jan 2026 18:29:20 GMT
pragma:no-cache
server:nginx
x-request-id:253-23569920

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48002-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic source class [Type]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48002-0"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48002-0 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48002-0\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#286

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81258-6"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:889
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:29:21 GMT
last-modified:Fri, 30 Jan 2026 18:29:21 GMT
pragma:no-cache
server:nginx
x-request-id:253-23569942

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81258-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Sample variant allelic frequency [NFr]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81258-6"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81258-6 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81258-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#287

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"82121-5"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:869
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:29:23 GMT
last-modified:Fri, 30 Jan 2026 18:29:23 GMT
pragma:no-cache
server:nginx
x-request-id:253-23569966

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82121-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic read depth"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "82121-5"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#82121-5 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#82121-5\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#288

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"53034-5"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:864
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:29:24 GMT
last-modified:Fri, 30 Jan 2026 18:29:24 GMT
pragma:no-cache
server:nginx
x-request-id:253-23569990

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "53034-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic state"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "53034-5"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#53034-5 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#53034-5\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#289

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"94186-4"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:892
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:29:26 GMT
last-modified:Fri, 30 Jan 2026 18:29:26 GMT
pragma:no-cache
server:nginx
x-request-id:253-23570012

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "94186-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Origin of germline genetic variant [Type]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "94186-4"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#94186-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#94186-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#290

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"82309-6"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:881
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:29:26 GMT
last-modified:Fri, 30 Jan 2026 18:29:26 GMT
pragma:no-cache
server:nginx
x-request-id:253-23570031

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82309-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Basis for allelic phase [Type]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "82309-6"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#82309-6 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#82309-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#291

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81252-9"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:875
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:29:28 GMT
last-modified:Fri, 30 Jan 2026 18:29:28 GMT
pragma:no-cache
server:nginx
x-request-id:253-23570042

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81252-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Discrete genetic variant"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81252-9"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81252-9 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81252-9\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#292

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"82155-3"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:889
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:29:29 GMT
last-modified:Fri, 30 Jan 2026 18:29:29 GMT
pragma:no-cache
server:nginx
x-request-id:253-23570061

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82155-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic structural variant copy number"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "82155-3"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#82155-3 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#82155-3\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#293

GET https://tx.fhir.org/r4/metadata HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
User-Agent: fhir/publisher

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:4378
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:29:40 GMT
pragma:no-cache
server:nginx
x-request-id:253-23570226

{"resourceType" : "CapabilityStatement","id" : "FhirServer","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><h2>Local User Conformance Statement</h2><p>FHIR v4.0.1 released 20251208221453.000Z. Server version 4.0.7 built 20251208221453.000Z</p><table class=\"grid\"><tr><th>Resource Type</th><th>Profile</th><th>Read</th><th>V-Read</th><th>Search</th><th>Update</th><th>Updates</th><th>Create</th><th>Delete</th><th>History</th></tr>\n</table>\n<p>Operations</p>\n<ul>\n <li>expand: see OperationDefinition/fso-expand</li>\n <li>lookup: see OperationDefinition/fso-lookup</li>\n <li>subsumes: see OperationDefinition/fso-subsumes</li>\n <li>validate-code: see OperationDefinition/fso-validate-code</li>\n <li>batch-validate-code: see OperationDefinition/fso-batch-validate-code</li>\n <li>translate: see OperationDefinition/fso-translate</li>\n <li>closure: see OperationDefinition/fso-closure</li>\n <li>versions: see OperationDefinition/fso-versions</li>\n</ul>\n</div>"},"extension" : [{"extension" : [{"url" : "definition","valueCanonical" : "http://hl7.org/fhir/uv/tx-tests/FeatureDefinition/test-version"},{"url" : "value","valueCode" : "1.8.0"},{"extension" : [{"url" : "name","valueCode" : "mode"},{"url" : "value","valueCode" : "tx.fhir.org"}],"url" : "qualifier"}],"url" : "http://hl7.org/fhir/uv/application-feature/StructureDefinition/feature"},{"extension" : [{"url" : "definition","valueCanonical" : "http://hl7.org/fhir/uv/tx-ecosystem/FeatureDefinition/CodeSystemAsParameter"},{"url" : "value","valueBoolean" : true}],"url" : "http://hl7.org/fhir/uv/application-feature/StructureDefinition/feature"}],"url" : "http://tx.fhir.org/r4/CapabilityStatement/tx","version" : "4.0.1-4.0.7","name" : "FHIRReferenceServer","title" : "FHIR Reference Server Conformance Statement","status" : "active","date" : "2026-01-30T18:29:40.662Z","contact" : [{"telecom" : [{"system" : "other","value" : "http://healthintersections.com.au/"}]}],"description" : "Standard Conformance Statement for the open source Reference FHIR Server provided by Health Intersections","kind" : "instance","instantiates" : ["http://hl7.org/fhir/CapabilityStatement/terminology-server","http://hl7.org/fhir/CapabilityStatement/terminology-server"],"software" : {"name" : "HealthIntersections Server","version" : "4.0.7","releaseDate" : "2025-12-08T22:14:53.000Z"},"implementation" : {"description" : "FHIR Server running at http://tx.fhir.org/r4","url" : "http://tx.fhir.org/r4"},"fhirVersion" : "4.0.1","format" : ["application/fhir+xml","application/fhir+json"],"rest" : [{"mode" : "server","security" : {"cors" : true},"resource" : [{"type" : "CodeSystem","interaction" : [{"code" : "read","documentation" : "Read a code system"},{"code" : "search-type","documentation" : "Search the code systems. Not that there a few major code systems that are not available through this API (SCT, LOINC etc)"}],"operation" : [{"name" : "validate-code","definition" : "http://hl7.org/fhir/OperationDefinition/CodeSystem-validate-code"},{"name" : "lookup","definition" : "http://hl7.org/fhir/OperationDefinition/CodeSystem-lookup"}]},{"type" : "ValueSet","interaction" : [{"code" : "read","documentation" : "Read a ValueSet"},{"code" : "search-type","documentation" : "Search the value sets"}],"operation" : [{"name" : "validate-code","definition" : "http://hl7.org/fhir/OperationDefinition/ValueSet-validate-code"},{"name" : "expand","definition" : "http://hl7.org/fhir/OperationDefinition/ValueSet-expand"}]}],"interaction" : [{"code" : "transaction"}],"operation" : [{"name" : "expand","definition" : "http://hl7.org/fhir/OperationDefinition/ValueSet-expand"},{"name" : "lookup","definition" : "http://hl7.org/fhir/OperationDefinition/ValueSet-lookup"},{"name" : "subsumes","definition" : "http://hl7.org/fhir/OperationDefinition/CodeSystem-subsumes"},{"name" : "validate-code","definition" : "http://hl7.org/fhir/OperationDefinition/Resource-validate-code"},{"name" : "batch-validate-code","definition" : "http://hl7.org/fhir/OperationDefinition/Resource-batch-validate-code"},{"name" : "translate","definition" : "http://hl7.org/fhir/OperationDefinition/ConceptMap-translate"},{"name" : "closure","definition" : "http://hl7.org/fhir/OperationDefinition/ConceptMap-closure"},{"name" : "versions","definition" : "http://tx.fhir.org/r4/OperationDefinition/fso-versions"}]}]}

#294

GET https://tx.fhir.org/r4/metadata?mode=terminology HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
User-Agent: fhir/publisher

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
connection:keep-alive
content-length:196124
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:29:40 GMT
server:nginx
x-request-id:253-23570228

{"resourceType" : "TerminologyCapabilities","id" : "FhirServer","url" : "http://tx.fhir.org/r4/TerminologyCapabilities/tx","version" : "2.0.0","name" : "FHIRReferenceServerTerminologyCapabilities","title" : "FHIR Reference Server Terminology Capability Statement","status" : "active","date" : "2026-01-26T20:57:33.083Z","contact" : [{"telecom" : [{"system" : "other","value" : "http://healthintersections.com.au/"}]}],"description" : "Standard Terminology Capability Statement for the open source Reference FHIR Server provided by Health Intersections","kind" : "instance","codeSystem" : [{"uri" : "http://cap.org/eCP","version" : [{"code" : "4.000.001"}]},{"uri" : "http://cds-hooks.hl7.org/CodeSystem/indicator","version" : [{"code" : "4.0.1"}]},{"uri" : "http://devices.fhir.org/CodeSystem/MDC-concept-status"},{"uri" : "http://devices.fhir.org/CodeSystem/MDC-designation-use"},{"uri" : "http://dicom.nema.org/resources/ontology/DCM","version" : [{"code" : "01"}]},{"uri" : "http://dicom.nema.org/resources/ontology/DCM","version" : [{"code" : "2025.3.20250714"}]},{"uri" : "http://fdasis.nlm.nih.gov","version" : [{"code" : "2024-06-22"}]},{"uri" : "http://healthit.gov/nhin/purposeofuse","version" : [{"code" : "2.0"}]},{"uri" : "http://hl7.org/fhir/abstract-types","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/account-status","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/action-cardinality-behavior","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/action-condition-kind","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/action-grouping-behavior","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/action-participant-type","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/action-precheck-behavior","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/action-relationship-type","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/action-required-behavior","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/action-selection-behavior","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/additionalmaterials","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/address-type","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/address-use","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/administrative-gender","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/adverse-event-actuality","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/allergy-intolerance-category","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/allergy-intolerance-criticality","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/allergy-intolerance-type","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/animal-genderstatus","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/animal-species","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/appointmentstatus","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/assert-direction-codes","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/assert-operator-codes","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/assert-response-code-types","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/asset-availability","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/audit-event-action","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/audit-event-outcome","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/binding-strength","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/bundle-type","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/capability-statement-kind","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/care-plan-activity-status","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/care-team-status","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/chargeitem-status","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/claim-use","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/code-search-support","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/CodeSystem/example","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/CodeSystem/medicationrequest-intent","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/CodeSystem/medicationrequest-status","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/CodeSystem/medication-statement-status","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/CodeSystem/medication-status","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/CodeSystem/status","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/CodeSystem/summary","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/CodeSystem/task-code","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/codesystem-content-mode","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/codesystem-hierarchy-meaning","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/compartment-type","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/composition-attestation-mode","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/composition-status","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/concept-map-equivalence","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/conceptmap-unmapped-mode","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/concept-properties","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/concept-property-type","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/concept-subsumption-outcome","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/conditional-delete-status","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/conditional-read-status","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/consent-data-meaning","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/consentperformer","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/consent-provision-type","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/consent-state-codes","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/constraint-severity","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/contact-point-system","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/contact-point-use","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/contract-action-status","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/contract-asset-context","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/contract-asset-scope","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/contract-asset-subtype","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/contract-asset-type","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/contract-decision-mode","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/contract-definition-subtype","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/contract-definition-type","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/contract-expiration-type","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/contract-legalstate","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/contract-party-role","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/contract-publicationstatus","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/contract-scope","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/contract-security-category","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/contract-security-classification","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/contract-security-control","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/contract-status","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/contributor-type","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/data-types","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/days-of-week","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/definition-resource-types","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/detectedissue-severity","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/device-action","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/device-definition-status","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/device-nametype","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/device-statement-status","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/device-status","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/diagnostic-report-status","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/discriminator-type","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/document-mode","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/document-reference-status","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/document-relationship-type","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/eligibilityrequest-purpose","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/eligibilityresponse-purpose","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/encounter-location-status","version" : [{"code" : "4.0.1"}]},{"uri" : "http://hl7.org/fhir/encounter-status","version" : [{"code" : "4.0.1"}]},{"uri" : 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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "122555007"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Venous blood specimen"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "122555007","display" : "Venous blood specimen"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://snomed.info/sct#122555007 (\"Venous blood specimen\")]\"\r\n0 0     : 0ms  : Check \"http://snomed.info/sct#122555007\"\r\n0 0     : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#296

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"13303-3","display":"HLA-A+B+C (class I) [Type]"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:944
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:30:24 GMT
last-modified:Fri, 30 Jan 2026 18:30:24 GMT
pragma:no-cache
server:nginx
x-request-id:253-23570864

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "13303-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "HLA-A+B+C (class I) [Type]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "13303-3","display" : "HLA-A+B+C (class I) [Type]"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#13303-3 (\"HLA-A+B+C (class I) [Type]\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#13303-3\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#297

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","version":"3.23","code":"HLA00001"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1702
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:30:24 GMT
last-modified:Fri, 30 Jan 2026 18:30:24 GMT
pragma:no-cache
server:nginx
x-request-id:253-23570891

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "HLA00001"},{"name" : "version","valueString" : "3.23"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla|3.23#HLA00001 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23#HLA00001\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23\"\r\n"}]}

#298

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","version":"3.23","code":"HLA00002"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
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cache-control:public, max-age=600
connection:keep-alive
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content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:30:25 GMT
last-modified:Fri, 30 Jan 2026 18:30:25 GMT
pragma:no-cache
server:nginx
x-request-id:253-23570893

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "HLA00002"},{"name" : "version","valueString" : "3.23"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla|3.23#HLA00002 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23#HLA00002\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23\"\r\n"}]}

#299

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"84414-2","display":"Haplotype name"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-length:908
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:30:26 GMT
last-modified:Fri, 30 Jan 2026 18:30:26 GMT
pragma:no-cache
server:nginx
x-request-id:253-23570896

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "84414-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Haplotype name"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "84414-2","display" : "Haplotype name"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#84414-2 (\"Haplotype name\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#84414-2\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#300

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","version":"3.23","code":"HLA-A*01:01:01G","display":"HLA-A*01:01:01G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1738
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:30:26 GMT
last-modified:Fri, 30 Jan 2026 18:30:26 GMT
pragma:no-cache
server:nginx
x-request-id:253-23570917

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "HLA-A*01:01:01G"},{"name" : "version","valueString" : "3.23"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla|3.23#HLA-A*01:01:01G (\"HLA-A*01:01:01G\")]\"\r\n0 0     : 0ms  : Check \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23#HLA-A*01:01:01G\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23\"\r\n"}]}

#301

GET https://tx-nordics.fhir.org/fhir/r4/CodeSystem?_format=json&url=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fgtr HTTP/1.0
User-Agent: hapi-fhir-tooling-client
Accept: application/fhir+json; fhirVersion=4.0

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:30:27 GMT
etag:W/"1767072433202"
last-modified:Fri, 30 Jan 2026 18:30:27 GMT
server:nginx
vary:Origin
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vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:db98a037-5a5c-4eb1-a197-d0a5dc3eb710
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x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:db98a037-5a5c-4eb1-a197-d0a5dc3eb710
x-xss-protection:0

{"resourceType":"Bundle","id":"167526b5-95f6-30ab-ad64-50d1b8318e74","meta":{"lastUpdated":"2026-01-30T19:30:27.079+01:00","tag":[{"system":"http://terminology.hl7.org/CodeSystem/v3-ObservationValue","code":"SUBSETTED","display":"Resource encoded in summary mode"}]},"type":"searchset","total":1,"link":[{"relation":"self","url":"https://tx-nordics.fhir.org/fhir/r4/CodeSystem?_format=json&_summary=true&url=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fgtr"}],"entry":[{"fullUrl":"https://tx-nordics.fhir.org/fhir/r4/CodeSystem/3181adda-0d14-477e-af16-5920d4ae52e5","resource":{"resourceType":"CodeSystem","id":"3181adda-0d14-477e-af16-5920d4ae52e5","meta":{"versionId":"1","lastUpdated":"2025-10-26T18:16:30.713+01:00","tag":[{"system":"http://terminology.hl7.org/CodeSystem/v3-ObservationValue","code":"SUBSETTED","display":"Resource encoded in summary mode"}]},"url":"https://www.ncbi.nlm.nih.gov/gtr","version":"1.0.1","name":"GTR","title":"Genetic Testing Registry","status":"active","experimental":false,"date":"2022-02-03T00:00:00-00:00","publisher":"National Center for Biotechnology Information, U.S. National Library of Medicine","contact":[{"name":"National Center for Biotechnology Information, U.S. National Library of Medicine; 8600 Rockville Pike, Bethesda MD, 20894 USA","telecom":[{"system":"url","value":"https://www.ncbi.nlm.nih.gov/"}]}],"caseSensitive":true,"content":"not-present"}}]}

#302

GET https://tx-nordics.fhir.org/fhir/r4/CodeSystem/3181adda-0d14-477e-af16-5920d4ae52e5 HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
User-Agent: fhir/publisher

200
cache-control:no-cache
content-location:https://tx-nordics.fhir.org/fhir/r4/CodeSystem/3181adda-0d14-477e-af16-5920d4ae52e5/_history/1
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:30:27 GMT
etag:W/"1"
last-modified:Sun, 26 Oct 2025 17:16:30 GMT
server:nginx
vary:Origin
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x-correlation-id:2ffc69d6-f0a0-41eb-b08e-c2278b2b38c1
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x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:2ffc69d6-f0a0-41eb-b08e-c2278b2b38c1
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{"resourceType":"CodeSystem","id":"3181adda-0d14-477e-af16-5920d4ae52e5","meta":{"versionId":"1","lastUpdated":"2025-10-26T18:16:30.713+01:00"},"text":{"status":"generated","div":"<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: CodeSystem GTR</b></p><a name=\"GTR\"/><a name=\"hcGTR\"/><p>This case-sensitive code system <code>https://www.ncbi.nlm.nih.gov/gtr</code> defines codes, but no codes are represented here</p></div>"},"url":"https://www.ncbi.nlm.nih.gov/gtr","version":"1.0.1","name":"GTR","title":"Genetic Testing Registry","status":"active","experimental":false,"date":"2022-02-03T00:00:00-00:00","publisher":"National Center for Biotechnology Information, U.S. National Library of Medicine","contact":[{"name":"National Center for Biotechnology Information, U.S. National Library of Medicine; 8600 Rockville Pike, Bethesda MD, 20894 USA","telecom":[{"system":"url","value":"https://www.ncbi.nlm.nih.gov/"}]}],"description":"The Genetic Testing Registry (GTR) provides a central location for voluntary submission of genetic test information by providers. The scope includes the test's purpose, methodology, validity, evidence of the test's usefulness, and laboratory contacts and credentials. The overarching goal of the GTR is to advance the public health and research into the genetic basis of health and disease.\r\n\r\nEach Test is a specific, orderable test from a particular laboratory, and is assigned a unique GTR accession number. The format is GTR00000001.1, with a leading prefix \"GTR\" followed by 8 digits, a period, then 1 or more digits representing the version. When a laboratory updates a registered test, a new version number is assigned.\r\n\r\nTo find all laboratories in GTR and all registered tests, see here https://www.ncbi.nlm.nih.gov/gtr/all/tests/?term=all%5Bsb%5D","copyright":"NCBI's Disclaimer and Copyright notice must be evident to users of your service.\r\n\r\nInformation that is created by or for the US government on this site is within the public domain. Public domain information on the National Library of Medicine (NLM) Web pages may be freely distributed and copied. However, it is requested that in any subsequent use of this work, NLM be given appropriate acknowledgment.\r\n\r\nNOTE: This site contains resources which incorporate material contributed or licensed by individuals, companies, or organizations that may be protected by U.S. and foreign copyright laws. These include, but are not limited to PubMed Central (PMC) (see PMC Copyright Notice at https://www.ncbi.nlm.nih.gov/pmc/about/copyright/), Bookshelf (see Bookshelf Copyright Notice at https://www.ncbi.nlm.nih.gov/books/about/copyright/), OMIM (see OMIM Copyright Status at https://omim.org/help/copyright), and PubChem. All persons reproducing, redistributing, or making commercial use of this information are expected to adhere to the terms and conditions asserted by the copyright holder. Transmission or reproduction of protected items beyond that allowed by fair use (https://www.copyright.gov/fls/fl102.html)(PDF) as defined in the copyright laws requires the written permission of the copyright owners.\r\n\r\nGeneral copyright, as stated on NCBI's GTR site (https://www.ncbi.nlm.nih.gov/gtr/), is as included in the Copyright Statement.","caseSensitive":true,"content":"not-present"}

#303

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"https://www.ncbi.nlm.nih.gov/gtr","code":"GTR000000000.0"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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date:Fri, 30 Jan 2026 18:30:28 GMT
server:nginx
vary:Origin
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vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:f3d0aca8-bcdd-4f2b-a232-e46b8dd7f9b0
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:f3d0aca8-bcdd-4f2b-a232-e46b8dd7f9b0
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"GTR000000000.0"},{"name":"system","valueUri":"https://www.ncbi.nlm.nih.gov/gtr"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system https://www.ncbi.nlm.nih.gov/gtr was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'https://www.ncbi.nlm.nih.gov/gtr' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"https://www.ncbi.nlm.nih.gov/gtr"},{"name":"message","valueString":"A definition for CodeSystem 'https://www.ncbi.nlm.nih.gov/gtr' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system https://www.ncbi.nlm.nih.gov/gtr was not found"}]}

#304

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48018-6","display":"Gene studied [ID]"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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date:Fri, 30 Jan 2026 18:30:29 GMT
last-modified:Fri, 30 Jan 2026 18:30:29 GMT
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48018-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Gene studied [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48018-6","display" : "Gene studied [ID]"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48018-6 (\"Gene studied [ID]\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48018-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#305

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:4931","display":"HLA-A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:4931"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#306

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"https://www.ncbi.nlm.nih.gov/gtr","code":"GTR000000000.0"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"GTR000000000.0"},{"name":"system","valueUri":"https://www.ncbi.nlm.nih.gov/gtr"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system https://www.ncbi.nlm.nih.gov/gtr was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'https://www.ncbi.nlm.nih.gov/gtr' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"https://www.ncbi.nlm.nih.gov/gtr"},{"name":"message","valueString":"A definition for CodeSystem 'https://www.ncbi.nlm.nih.gov/gtr' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system https://www.ncbi.nlm.nih.gov/gtr was not found"}]}

#307

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:4931","display":"HLA-A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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date:Fri, 30 Jan 2026 18:30:31 GMT
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:4931"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#308

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:4931"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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date:Fri, 30 Jan 2026 18:30:31 GMT
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:4931"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}]}

#309

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","version":"3.23","code":"HLA-A*01:02","display":"HLA-A*01:02"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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date:Fri, 30 Jan 2026 18:30:32 GMT
last-modified:Fri, 30 Jan 2026 18:30:32 GMT
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "HLA-A*01:02"},{"name" : "version","valueString" : "3.23"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"()\"\r\n16 0    : 0ms  : Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla|3.23#HLA-A*01:02 (\"HLA-A*01:02\")]\"\r\n16 0    : 0ms  : Check \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23#HLA-A*01:02\"\r\n16 0    : 0ms  : Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23\"\r\n"}]}

#310

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"84413-4","display":"Genotype display name"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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last-modified:Fri, 30 Jan 2026 18:30:33 GMT
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "84413-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genotype display name"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "84413-4","display" : "Genotype display name"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#84413-4 (\"Genotype display name\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#84413-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#311

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://glstring.org","version":"1.0","code":"hla#3.23.0#HLA-A:01:01G+HLA-A*01:02"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://glstring.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://glstring.org"},{"name" : "code","valueCode" : "hla#3.23.0#HLA-A:01:01G+HLA-A*01:02"},{"name" : "version","valueString" : "1.0"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://glstring.org|1.0#hla#3.23.0#HLA-A:01:01G+HLA-A*01:02 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://glstring.org|1.0#hla#3.23.0#HLA-A:01:01G+HLA-A*01:02\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://glstring.org|1.0\"\r\n"}]}

#312

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"https://www.ncbi.nlm.nih.gov/gtr","code":"GTR000000000.0"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"GTR000000000.0"},{"name":"system","valueUri":"https://www.ncbi.nlm.nih.gov/gtr"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system https://www.ncbi.nlm.nih.gov/gtr was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'https://www.ncbi.nlm.nih.gov/gtr' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"https://www.ncbi.nlm.nih.gov/gtr"},{"name":"message","valueString":"A definition for CodeSystem 'https://www.ncbi.nlm.nih.gov/gtr' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system https://www.ncbi.nlm.nih.gov/gtr was not found"}]}

#313

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","version":"3.23","code":"HLA00162"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
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connection:keep-alive
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content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:30:34 GMT
last-modified:Fri, 30 Jan 2026 18:30:34 GMT
pragma:no-cache
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x-request-id:253-23571053

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "HLA00162"},{"name" : "version","valueString" : "3.23"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla|3.23#HLA00162 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23#HLA00162\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23\"\r\n"}]}

#314

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","version":"3.23","code":"HLA00381"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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date:Fri, 30 Jan 2026 18:30:34 GMT
last-modified:Fri, 30 Jan 2026 18:30:34 GMT
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "HLA00381"},{"name" : "version","valueString" : "3.23"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla|3.23#HLA00381 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23#HLA00381\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23\"\r\n"}]}

#315

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","version":"3.23","code":"HGG00041","display":"HLA-B*15:01:01G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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cache-control:public, max-age=600
connection:keep-alive
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content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:30:34 GMT
last-modified:Fri, 30 Jan 2026 18:30:34 GMT
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "HGG00041"},{"name" : "version","valueString" : "3.23"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla|3.23#HGG00041 (\"HLA-B*15:01:01G\")]\"\r\n0 0     : 0ms  : Check \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23#HGG00041\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23\"\r\n"}]}

#316

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:4932","display":"HLA-B"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:30:35 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:756b395c-509c-4115-92c3-db23c96efd5c
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x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:756b395c-509c-4115-92c3-db23c96efd5c
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:4932"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#317

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:4932","display":"HLA-B"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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date:Fri, 30 Jan 2026 18:30:35 GMT
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:4932"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#318

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:4932"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:30:36 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
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vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:4932"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}]}

#319

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","version":"3.23","code":"HLA-B*57:01:01G","display":"HLA-B*57:01:01G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1738
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:30:36 GMT
last-modified:Fri, 30 Jan 2026 18:30:36 GMT
pragma:no-cache
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x-request-id:253-23571088

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "HLA-B*57:01:01G"},{"name" : "version","valueString" : "3.23"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla|3.23#HLA-B*57:01:01G (\"HLA-B*57:01:01G\")]\"\r\n0 0     : 0ms  : Check \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23#HLA-B*57:01:01G\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23\"\r\n"}]}

#320

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://glstring.org","version":"1.0","code":"hla#3.23.0#HLA-B*15:01:01G+HLA-B*57:01:01G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
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cache-control:public, max-age=600
connection:keep-alive
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date:Fri, 30 Jan 2026 18:30:36 GMT
last-modified:Fri, 30 Jan 2026 18:30:36 GMT
pragma:no-cache
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x-request-id:253-23571093

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://glstring.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://glstring.org"},{"name" : "code","valueCode" : "hla#3.23.0#HLA-B*15:01:01G+HLA-B*57:01:01G"},{"name" : "version","valueString" : "1.0"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"()\"\r\n16 0    : 0ms  : Validate \"[http://glstring.org|1.0#hla#3.23.0#HLA-B*15:01:01G+HLA-B*57:01:01G (\"\")]\"\r\n16 0    : 0ms  : Check \"http://glstring.org|1.0#hla#3.23.0#HLA-B*15:01:01G+HLA-B*57:01:01G\"\r\n16 0    : 0ms  : Didn't find CodeSystem \"http://glstring.org|1.0\"\r\n"}]}

#321

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","version":"3.23","code":"HLA00401"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1702
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:30:36 GMT
last-modified:Fri, 30 Jan 2026 18:30:36 GMT
pragma:no-cache
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x-request-id:253-23571101

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "HLA00401"},{"name" : "version","valueString" : "3.23"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla|3.23#HLA00401 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23#HLA00401\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23\"\r\n"}]}

#322

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","version":"3.23","code":"HLA00413"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1702
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:30:36 GMT
last-modified:Fri, 30 Jan 2026 18:30:36 GMT
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "HLA00413"},{"name" : "version","valueString" : "3.23"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla|3.23#HLA00413 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23#HLA00413\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23\"\r\n"}]}

#323

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","version":"3.23","code":"HLA-C*01:02:01G","display":"HLA-C*01:02:01G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1738
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:30:37 GMT
last-modified:Fri, 30 Jan 2026 18:30:37 GMT
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "HLA-C*01:02:01G"},{"name" : "version","valueString" : "3.23"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla|3.23#HLA-C*01:02:01G (\"HLA-C*01:02:01G\")]\"\r\n0 0     : 0ms  : Check \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23#HLA-C*01:02:01G\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23\"\r\n"}]}

#324

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:4933","display":"HLA-C"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:30:37 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:79526c2a-8507-435c-ab27-2357e47a19b6
x-frame-options:DENY
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x-request-id:79526c2a-8507-435c-ab27-2357e47a19b6
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:4933"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#325

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:4933","display":"HLA-C"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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date:Fri, 30 Jan 2026 18:30:38 GMT
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:4933"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#326

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:4933"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:30:38 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
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vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:4933"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}]}

#327

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://glstring.org","version":"1.0","code":"hla#3.23.0#HLA-C*01:02:01G+HLA-C*03:04:01G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1700
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:30:38 GMT
last-modified:Fri, 30 Jan 2026 18:30:38 GMT
pragma:no-cache
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x-request-id:253-23571132

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://glstring.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://glstring.org"},{"name" : "code","valueCode" : "hla#3.23.0#HLA-C*01:02:01G+HLA-C*03:04:01G"},{"name" : "version","valueString" : "1.0"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://glstring.org|1.0#hla#3.23.0#HLA-C*01:02:01G+HLA-C*03:04:01G (\"\")]\"\r\n0 0     : 0ms  : Check \"http://glstring.org|1.0#hla#3.23.0#HLA-C*01:02:01G+HLA-C*03:04:01G\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://glstring.org|1.0\"\r\n"}]}

#328

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","version":"3.23"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1643
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:30:39 GMT
last-modified:Fri, 30 Jan 2026 18:30:38 GMT
pragma:no-cache
server:nginx
x-request-id:253-23571136

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "version","valueString" : "3.23"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla|3.23# (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23#\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23\"\r\n"}]}

#329

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"51969-4","display":"Genetic analysis report"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"report-codes","meta":{"lastUpdated":"2019-11-01T09:29:23.356+11:00","profile":["http://hl7.org/fhir/StructureDefinition/shareablevalueset"]},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"oo"}],"url":"http://hl7.org/fhir/ValueSet/report-codes","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.233"}],"version":"4.0.1","name":"LOINCDiagnosticReportCodes","title":"LOINC Diagnostic Report Codes","status":"draft","experimental":false,"date":"2019-11-01T09:29:23+11:00","publisher":"FHIR Project team","contact":[{"telecom":[{"system":"url","value":"http://hl7.org/fhir"}]}],"description":"This value set includes LOINC codes that relate to Diagnostic Observations.","copyright":"This content from LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use.","compose":{"include":[{"system":"http://loinc.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1176
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:30:39 GMT
last-modified:Fri, 30 Jan 2026 18:30:39 GMT
pragma:no-cache
server:nginx
x-request-id:253-23571137

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51969-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic analysis report"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "51969-4","display" : "Genetic analysis report"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/report-codes|4.0.1 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#51969-4 (\"Genetic analysis report\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#51969-4\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org) at CodeableConcept.coding[0]\r\n0 0     : 0ms  : Code \"51969-4\" found in http://loinc.org|2.81\r\n"}]}

#330

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"69548-6","display":"Genetic variant assessment"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:944
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:30:41 GMT
last-modified:Fri, 30 Jan 2026 18:30:41 GMT
pragma:no-cache
server:nginx
x-request-id:253-23571156

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69548-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic variant assessment"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "69548-6","display" : "Genetic variant assessment"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#69548-6 (\"Genetic variant assessment\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#69548-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#331

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA9633-4","display":"Present"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:891
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:30:43 GMT
last-modified:Fri, 30 Jan 2026 18:30:43 GMT
pragma:no-cache
server:nginx
x-request-id:253-23571183

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA9633-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Present"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA9633-4","display" : "Present"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA9633-4 (\"Present\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA9633-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#332

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"62374-4","display":"Human reference sequence assembly version"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:989
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:30:43 GMT
last-modified:Fri, 30 Jan 2026 18:30:43 GMT
pragma:no-cache
server:nginx
x-request-id:253-23571209

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "62374-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Human reference sequence assembly version"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "62374-4","display" : "Human reference sequence assembly version"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#62374-4 (\"Human reference sequence assembly version\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#62374-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#333

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA14029-5","display":"GRCh37"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:892
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:30:45 GMT
last-modified:Fri, 30 Jan 2026 18:30:45 GMT
pragma:no-cache
server:nginx
x-request-id:253-23571226

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA14029-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "GRCh37"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA14029-5","display" : "GRCh37"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA14029-5 (\"GRCh37\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA14029-5\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#334

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48013-7","display":"Genomic reference sequence ID"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:955
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:30:46 GMT
last-modified:Fri, 30 Jan 2026 18:30:46 GMT
pragma:no-cache
server:nginx
x-request-id:253-23571249

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48013-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic reference sequence [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48013-7","display" : "Genomic reference sequence ID"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48013-7 (\"Genomic reference sequence ID\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48013-7\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#335

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:30:47 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:8afaef13-ba73-44c7-ba81-d46b0198b3ba
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:8afaef13-ba73-44c7-ba81-d46b0198b3ba
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#336

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"53034-5","display":"Allelic state"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:905
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:30:48 GMT
last-modified:Fri, 30 Jan 2026 18:30:48 GMT
pragma:no-cache
server:nginx
x-request-id:253-23571283

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "53034-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic state"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "53034-5","display" : "Allelic state"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#53034-5 (\"Allelic state\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#53034-5\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#337

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6706-1","display":"heterozygous"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:906
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:30:49 GMT
last-modified:Fri, 30 Jan 2026 18:30:49 GMT
pragma:no-cache
server:nginx
x-request-id:253-23571295

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6706-1"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Heterozygous"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6706-1","display" : "heterozygous"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA6706-1 (\"heterozygous\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA6706-1\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#338

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"69547-8","display":"Ref nucleotide"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:917
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:30:50 GMT
last-modified:Fri, 30 Jan 2026 18:30:50 GMT
pragma:no-cache
server:nginx
x-request-id:253-23571314

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69547-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic ref allele [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "69547-8","display" : "Ref nucleotide"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#69547-8 (\"Ref nucleotide\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#69547-8\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#339

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"69551-0","display":"Alt allele"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:909
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:30:52 GMT
last-modified:Fri, 30 Jan 2026 18:30:52 GMT
pragma:no-cache
server:nginx
x-request-id:253-23571332

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69551-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic alt allele [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "69551-0","display" : "Alt allele"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#69551-0 (\"Alt allele\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#69551-0\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#340

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"92822-6","display":"Genomic coord system"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:938
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:30:53 GMT
last-modified:Fri, 30 Jan 2026 18:30:53 GMT
pragma:no-cache
server:nginx
x-request-id:253-23571349

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "92822-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic coordinate system [Type]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "92822-6","display" : "Genomic coord system"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#92822-6 (\"Genomic coord system\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#92822-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#341

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA30102-0"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:885
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:30:55 GMT
last-modified:Fri, 30 Jan 2026 18:30:55 GMT
pragma:no-cache
server:nginx
x-request-id:253-23571365

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA30102-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "1-based character counting"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA30102-0"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA30102-0 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA30102-0\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#342

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA9633-4","display":"Present"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL1971-2","name":"LOINCAnswersLL1971-2","title":"LOINC Answer Codes for LL1971-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL1971-2"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1173
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:30:57 GMT
last-modified:Fri, 30 Jan 2026 18:30:57 GMT
pragma:no-cache
server:nginx
x-request-id:253-23571387

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA9633-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Present"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA9633-4","display" : "Present"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://loinc.org/vs/LL1971-2 for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL1971-2)\"\r\n16 0    : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n16 0    : 0ms  : Validate \"[http://loinc.org#LA9633-4 (\"Present\")]\"\r\n16 0    : 0ms  : Check \"http://loinc.org#LA9633-4\"\r\n16 0    : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0    : 0ms  : check code in (http://loinc.org)(LIST=LL1971-2) at CodeableConcept.coding[0]\r\n2016 2000: 2000ms : Filter \"LIST=LL1971-2\": Code \"LA9633-4\" found in http://loinc.org|2.81\r\n"}]}

#343

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA14029-5","display":"GRCh37"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL1040-6","name":"LOINCAnswersLL1040-6","title":"LOINC Answer Codes for LL1040-6","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL1040-6"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1175
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:30:59 GMT
last-modified:Fri, 30 Jan 2026 18:30:59 GMT
pragma:no-cache
server:nginx
x-request-id:253-23571420

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA14029-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "GRCh37"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA14029-5","display" : "GRCh37"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL1040-6 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL1040-6)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA14029-5 (\"GRCh37\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA14029-5\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL1040-6) at CodeableConcept.coding[0]\r\n2000 2000: 2000ms : Filter \"LIST=LL1040-6\": Code \"LA14029-5\" found in http://loinc.org|2.81\r\n"}]}

#344

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6706-1","display":"heterozygous"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL381-5","name":"LOINCAnswersLL381-5","title":"LOINC Answer Codes for LL381-5","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL381-5"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1184
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:31:01 GMT
last-modified:Fri, 30 Jan 2026 18:31:01 GMT
pragma:no-cache
server:nginx
x-request-id:253-23571452

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6706-1"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Heterozygous"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6706-1","display" : "heterozygous"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL381-5 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL381-5)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA6706-1 (\"heterozygous\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA6706-1\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL381-5) at CodeableConcept.coding[0]\r\n2015 2015: 2015ms : Filter \"LIST=LL381-5\": Code \"LA6706-1\" found in http://loinc.org|2.81\r\n"}]}

#345

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA30102-0"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL5323-2","name":"LOINCAnswersLL5323-2","title":"LOINC Answer Codes for LL5323-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL5323-2"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1168
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:31:03 GMT
last-modified:Fri, 30 Jan 2026 18:31:03 GMT
pragma:no-cache
server:nginx
x-request-id:253-23571487

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA30102-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "1-based character counting"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA30102-0"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL5323-2 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL5323-2)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n16 16   : 16ms : Validate \"[http://loinc.org#LA30102-0 (\"\")]\"\r\n16 0    : 16ms : Check \"http://loinc.org#LA30102-0\"\r\n16 0    : 16ms : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0    : 16ms : check code in (http://loinc.org)(LIST=LL5323-2) at CodeableConcept.coding[0]\r\n2016 2000: 2016ms : Filter \"LIST=LL5323-2\": Code \"LA30102-0\" found in http://loinc.org|2.81\r\n"}]}

#346

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6705-3","display":"homozygous"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:900
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:31:05 GMT
last-modified:Fri, 30 Jan 2026 18:31:05 GMT
pragma:no-cache
server:nginx
x-request-id:253-23571523

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6705-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Homozygous"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6705-3","display" : "homozygous"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"()\"\r\n16 0    : 0ms  : Validate \"[http://loinc.org#LA6705-3 (\"homozygous\")]\"\r\n16 0    : 0ms  : Check \"http://loinc.org#LA6705-3\"\r\n16 0    : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#347

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6705-3","display":"homozygous"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL381-5","name":"LOINCAnswersLL381-5","title":"LOINC Answer Codes for LL381-5","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL381-5"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1178
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:31:07 GMT
last-modified:Fri, 30 Jan 2026 18:31:07 GMT
pragma:no-cache
server:nginx
x-request-id:253-23571540

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6705-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Homozygous"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6705-3","display" : "homozygous"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL381-5 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL381-5)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA6705-3 (\"homozygous\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA6705-3\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL381-5) at CodeableConcept.coding[0]\r\n2015 2015: 2015ms : Filter \"LIST=LL381-5\": Code \"LA6705-3\" found in http://loinc.org|2.81\r\n"}]}

#348

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

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#349

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
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#350

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
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#351

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
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#352

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
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{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81252-9","display":"Discrete genetic variant"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81252-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Discrete genetic variant"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81252-9","display" : "Discrete genetic variant"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81252-9 (\"Discrete genetic variant\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81252-9\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#353

GET https://tx-nordics.fhir.org/fhir/r4/CodeSystem?_format=json&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fclinvar HTTP/1.0
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200
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{"resourceType":"Bundle","id":"568722e4-f51a-3bcd-ae44-e169fe449a94","meta":{"lastUpdated":"2026-01-30T19:31:20.882+01:00","tag":[{"system":"http://terminology.hl7.org/CodeSystem/v3-ObservationValue","code":"SUBSETTED","display":"Resource encoded in summary mode"}]},"type":"searchset","total":1,"link":[{"relation":"self","url":"https://tx-nordics.fhir.org/fhir/r4/CodeSystem?_format=json&_summary=true&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fclinvar"}],"entry":[{"fullUrl":"https://tx-nordics.fhir.org/fhir/r4/CodeSystem/cbbd278c-71b9-4b25-8f2f-8e4d011621ee","resource":{"resourceType":"CodeSystem","id":"cbbd278c-71b9-4b25-8f2f-8e4d011621ee","meta":{"versionId":"1","lastUpdated":"2025-10-26T18:16:35.028+01:00","tag":[{"system":"http://terminology.hl7.org/CodeSystem/v3-ObservationValue","code":"SUBSETTED","display":"Resource encoded in summary mode"}]},"url":"http://www.ncbi.nlm.nih.gov/clinvar","version":"1.0.1","name":"ClinVarV","title":"ClinVar Variant ID","status":"active","experimental":false,"date":"2022-03-11T00:00:00-00:00","publisher":"National Center for Biotechnology Information, U.S. National Library of Medicine","contact":[{"name":"National Center for Biotechnology Information, U.S. National Library of Medicine; 8600 Rockville Pike, Bethesda MD, 20894 USA","telecom":[{"system":"url","value":"https://www.ncbi.nlm.nih.gov/clinvar/"}]}],"caseSensitive":true,"content":"not-present"}}]}

#354

GET https://tx-nordics.fhir.org/fhir/r4/CodeSystem/cbbd278c-71b9-4b25-8f2f-8e4d011621ee HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
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200
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date:Fri, 30 Jan 2026 18:31:21 GMT
etag:W/"1"
last-modified:Sun, 26 Oct 2025 17:16:35 GMT
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{"resourceType":"CodeSystem","id":"cbbd278c-71b9-4b25-8f2f-8e4d011621ee","meta":{"versionId":"1","lastUpdated":"2025-10-26T18:16:35.028+01:00"},"text":{"status":"generated","div":"<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: CodeSystem ClinVarV</b></p><a name=\"ClinVarV\"/><a name=\"hcClinVarV\"/><p>This case-sensitive code system <code>http://www.ncbi.nlm.nih.gov/clinvar</code> defines codes, but no codes are represented here</p></div>"},"url":"http://www.ncbi.nlm.nih.gov/clinvar","version":"1.0.1","name":"ClinVarV","title":"ClinVar Variant ID","status":"active","experimental":false,"date":"2022-03-11T00:00:00-00:00","publisher":"National Center for Biotechnology Information, U.S. National Library of Medicine","contact":[{"name":"National Center for Biotechnology Information, U.S. National Library of Medicine; 8600 Rockville Pike, Bethesda MD, 20894 USA","telecom":[{"system":"url","value":"https://www.ncbi.nlm.nih.gov/clinvar/"}]}],"description":"ClinVar is a freely accessible, public archive of reports of the relationships among human variations and phenotypes, with supporting evidence. ClinVar thus facilitates access to and communication about the relationships asserted between human variation and observed health status, and the history of that interpretation. ClinVar processes submissions reporting variants found in patient samples, assertions made regarding their clinical significance, information about the submitter, and other supporting data. The alleles described in submissions are mapped to reference sequences, and reported according to the HGVS standard. ClinVar then presents the data for interactive users as well as those wishing to use ClinVar in daily workflows and other local applications. ClinVar works in collaboration with interested organizations to meet the needs of the medical genetics community as efficiently and effectively as possible. Read more about using ClinVar.\r\n\r\nClinVar supports submissions of differing levels of complexity. The submission may be as simple as a representation of an allele and its interpretation (sometimes termed a variant-level submission), or as detailed as providing multiple types of structured observational (case-level) or experimental evidence about the effect of the variation on phenotype. A major goal is to support computational (re)evaluation, both of genotypes and assertions, and to enable the ongoing evolution and development of knowledge regarding variations and associated phenotypes. ClinVar is an active partner of the ClinGen project, providing data for evaluation and archiving the results of interpretation by recognized expert panels and providers of practice guidelines (see https://www.ncbi.nlm.nih.gov/clinvar/docs/review_guidelines/). ClinVar archives and versions submissions which means that when submitters update their records, the previous version is retained for review. Read more about submitting data to ClinVar at https://www.ncbi.nlm.nih.gov/clinvar/docs/submit. \r\n\r\nThe level of confidence in the accuracy of variation calls and assertions of clinical significance depends in large part on the supporting evidence, so this information, when available, is collected and visible to users. Because the availability of supporting evidence may vary, particularly in regard to retrospective data aggregated from published literature, the archive accepts submissions from multiple groups, and aggregates related information, to reflect transparently both consensus and conflicting assertions of clinical significance. A review status is also assigned to any assertion, to support communication about the trustworthiness of any assertion. Domain experts are encouraged to apply for recognition as an expert panel (more info at https://www.ncbi.nlm.nih.gov/clinvar/docs/review_guidelines/). \r\n\r\nAccessions, with the format SCV000000000.0, are assigned to each submitted record. If there are multiple submitted records about the same variation/condition pair, they are aggregated within ClinVar's data flow and reported as a reference accession with the format RCV000000000.0. Because of this model, one variant will be included in multiple RCV accessions whenever different conditions are reported for that variant. Submitted records for the same variation are also aggregated and reported as an accession with the format VCV000000000.0. This aggregation lets a user review all submitted data for a variant, regardless of the condition for which it was interpreted.\r\n\r\nClinVar archives submitted information, and adds identifiers and other data that may be available about a variant or condition from other public resources. However ClinVar neither curates content nor modifies interpretations independent of an explicit submission. If you have data that differs from what is currently represented in ClinVar, we encourage you to submit your data and the evidence supporting your interpretation. There is a submission wizard to guide you through that process. See https://www.ncbi.nlm.nih.gov/variation/clinvar_single_wizard/. \r\n\r\nIf you are submitting variants that were interpreted as part of work funded by the NIH, please consult your program officer about expectations for submissions to ClinVar.","copyright":"Information that is created by or for the US government are within the public domain. Public domain information on the National Library of Medicine (NLM) Web pages may be freely distributed and copied. However, it is requested that in any subsequent use of this work, NLM be given appropriate acknowledgment.\r\n\r\nNOTE: This site contains resources which incorporate material contributed or licensed by individuals, companies, or organizations that may be protected by U.S. and foreign copyright laws. These include, but are not limited to PubMed Central (PMC) (see PMC Copyright Notice via https://www.ncbi.nlm.nih.gov/pmc/about/copyright/), Bookshelf (see Bookshelf Copyright Notice via https://www.ncbi.nlm.nih.gov/books/about/copyright/), OMIM (see OMIM Copyright Status via https://omim.org/help/copyright), and PubChem. All persons reproducing, redistributing, or making commercial use of this information are expected to adhere to the terms and conditions asserted by the copyright holder. Transmission or reproduction of protected items beyond that allowed by fair use (https://www.copyright.gov/fls/fl102.html)(PDF) as defined in the copyright laws requires the written permission of the copyright owners.\r\n\r\nFor information on NCBI's policies and disclaimers for use, see here https://www.ncbi.nlm.nih.gov/home/about/policies/.","caseSensitive":true,"content":"not-present"}

#355

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","code":"30880","display":"NM_014049.4(ACAD9):c.1249C>T (p.Arg417Cys)"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:31:21 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:9ff6fa0f-8b7b-4b8c-92fc-61a17f514099
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:9ff6fa0f-8b7b-4b8c-92fc-61a17f514099
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"30880"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/clinvar"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/clinvar was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/clinvar"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/clinvar was not found"}]}

#356

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:21497","display":"ACAD9"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:31:22 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:b562e54c-7d6d-4158-9b6d-ac4cee5f12a8
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:b562e54c-7d6d-4158-9b6d-ac4cee5f12a8
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:21497"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#357

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_014049.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:31:23 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:91826dfd-7de9-4c8d-8d65-169a1bdc48db
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:91826dfd-7de9-4c8d-8d65-169a1bdc48db
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NM_014049.4"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#358

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NG_017064.1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:31:23 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:23098347-e4b6-4380-8f1c-c9fb86cf57e3
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:23098347-e4b6-4380-8f1c-c9fb86cf57e3
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NG_017064.1"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#359

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000003.11:g.128625063C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:848
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:31:23 GMT
last-modified:Fri, 30 Jan 2026 18:31:23 GMT
pragma:no-cache
server:nginx
x-request-id:253-23571739

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000003.11:g.128625063C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000003.11:g.128625063C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000003.11:g.128625063C>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000003.11:g.128625063C>T\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#360

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/projects/SNP","code":"rs368949613"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:31:24 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:e419d6a2-1b40-47fb-a688-9d2001e2249a
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:e419d6a2-1b40-47fb-a688-9d2001e2249a
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"rs368949613"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/projects/SNP was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/projects/SNP was not found"}]}

#361

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_014049.4:c.1249C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:824
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:31:24 GMT
last-modified:Fri, 30 Jan 2026 18:31:24 GMT
pragma:no-cache
server:nginx
x-request-id:253-23571747

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_014049.4:c.1249C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_014049.4:c.1249C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_014049.4:c.1249C>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_014049.4:c.1249C>T\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#362

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_054768.2:p.Arg417Cys"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:832
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:31:24 GMT
last-modified:Fri, 30 Jan 2026 18:31:24 GMT
pragma:no-cache
server:nginx
x-request-id:253-23571752

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_054768.2:p.Arg417Cys"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_054768.2:p.Arg417Cys"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_054768.2:p.Arg417Cys (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_054768.2:p.Arg417Cys\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#363

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6690-7","display":"Substitution"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:906
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:31:26 GMT
last-modified:Fri, 30 Jan 2026 18:31:26 GMT
pragma:no-cache
server:nginx
x-request-id:253-23571753

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6690-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Substitution"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6690-7","display" : "Substitution"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA6690-7 (\"Substitution\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA6690-7\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#364

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6683-2","display":"Germline"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:894
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:31:27 GMT
last-modified:Fri, 30 Jan 2026 18:31:27 GMT
pragma:no-cache
server:nginx
x-request-id:253-23571770

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6683-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Germline"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6683-2","display" : "Germline"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA6683-2 (\"Germline\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA6683-2\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#365

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6706-1","display":"Heterozygous"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:906
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:31:29 GMT
last-modified:Fri, 30 Jan 2026 18:31:29 GMT
pragma:no-cache
server:nginx
x-request-id:253-23571787

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6706-1"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Heterozygous"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6706-1","display" : "Heterozygous"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA6706-1 (\"Heterozygous\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA6706-1\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#366

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:21497","display":"ACAD9"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:31:29 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:cd753cb9-7576-4911-883d-9a56896c49b7
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:cd753cb9-7576-4911-883d-9a56896c49b7
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:21497"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#367

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:21497"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:31:30 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:9ce9d19b-8eb2-4784-bc26-22bfc9064844
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:9ce9d19b-8eb2-4784-bc26-22bfc9064844
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:21497"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}]}

#368

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000003.11:g.128625063C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1156
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:31:30 GMT
last-modified:Fri, 30 Jan 2026 18:31:30 GMT
pragma:no-cache
server:nginx
x-request-id:253-23571810

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000003.11:g.128625063C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000003.11:g.128625063C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000003.11:g.128625063C>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000003.11:g.128625063C>T\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n78 78   : 78ms : Code \"NC_000003.11:g.128625063C>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#369

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_014049.4:c.1249C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1126
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:31:30 GMT
last-modified:Fri, 30 Jan 2026 18:31:30 GMT
pragma:no-cache
server:nginx
x-request-id:253-23571813

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_014049.4:c.1249C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_014049.4:c.1249C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_014049.4:c.1249C>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_014049.4:c.1249C>T\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n78 78   : 78ms : Code \"NM_014049.4:c.1249C>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#370

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_054768.2:p.Arg417Cys"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1136
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:31:30 GMT
last-modified:Fri, 30 Jan 2026 18:31:30 GMT
pragma:no-cache
server:nginx
x-request-id:253-23571816

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_054768.2:p.Arg417Cys"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_054768.2:p.Arg417Cys"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_054768.2:p.Arg417Cys (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_054768.2:p.Arg417Cys\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n62 62   : 62ms : Code \"NP_054768.2:p.Arg417Cys\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#371

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6690-7","display":"Substitution"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"dna-change-type-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs","version":"4.0.0-cibuild","name":"DNAChangeTypeVS","title":"DNA Change Type","status":"active","experimental":false,"date":"2026-01-30T18:21:39+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"DNA Change Type of a variant.","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0002072"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2193
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:31:30 GMT
last-modified:Fri, 30 Jan 2026 18:31:30 GMT
pragma:no-cache
server:nginx
x-request-id:253-23571817

{"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs|4.0.0-cibuild'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6690-7","display" : "Substitution"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA6690-7 ('Substitution')' was not found in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs|4.0.0-cibuild'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs|4.0.0-cibuild'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15   : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs|4.0.0-cibuild for validation purposes\r\n15 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n15 0    : 0ms  : Prepare include: \"(http://www.sequenceontology.org)(concept<<SO:0002072)\"\r\n15 0    : 0ms  : CodeSystem version  not found: \"http://www.sequenceontology.org\"\r\n15 0    : 0ms  : Validate \"[http://loinc.org#LA6690-7 (\"Substitution\")]\"\r\n15 0    : 0ms  : Check \"http://loinc.org#LA6690-7\"\r\n"}]}

#372

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6683-2","display":"Germline"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL378-1","name":"LOINCAnswersLL378-1","title":"LOINC Answer Codes for LL378-1","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL378-1"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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date:Fri, 30 Jan 2026 18:31:32 GMT
last-modified:Fri, 30 Jan 2026 18:31:32 GMT
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6683-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Germline"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6683-2","display" : "Germline"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL378-1 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL378-1)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA6683-2 (\"Germline\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA6683-2\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL378-1) at CodeableConcept.coding[0]\r\n2016 2016: 2016ms : Filter \"LIST=LL378-1\": Code \"LA6683-2\" found in http://loinc.org|2.81\r\n"}]}

#373

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6706-1","display":"Heterozygous"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL381-5","name":"LOINCAnswersLL381-5","title":"LOINC Answer Codes for LL381-5","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL381-5"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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date:Fri, 30 Jan 2026 18:31:34 GMT
last-modified:Fri, 30 Jan 2026 18:31:34 GMT
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6706-1"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Heterozygous"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6706-1","display" : "Heterozygous"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://loinc.org/vs/LL381-5 for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL381-5)\"\r\n16 0    : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n16 0    : 0ms  : Validate \"[http://loinc.org#LA6706-1 (\"Heterozygous\")]\"\r\n16 0    : 0ms  : Check \"http://loinc.org#LA6706-1\"\r\n16 0    : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0    : 0ms  : check code in (http://loinc.org)(LIST=LL381-5) at CodeableConcept.coding[0]\r\n2016 2000: 2000ms : Filter \"LIST=LL381-5\": Code \"LA6706-1\" found in http://loinc.org|2.81\r\n"}]}

#374

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6668-3","display":"Pathogenic"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
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content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:31:36 GMT
last-modified:Fri, 30 Jan 2026 18:31:36 GMT
pragma:no-cache
server:nginx
x-request-id:253-23571871

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6668-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Pathogenic"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6668-3","display" : "Pathogenic"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA6668-3 (\"Pathogenic\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA6668-3\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#375

GET https://tx-nordics.fhir.org/fhir/r4/CodeSystem?_format=json&url=http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fmondo.owl HTTP/1.0
User-Agent: hapi-fhir-tooling-client
Accept: application/fhir+json; fhirVersion=4.0

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:31:36 GMT
etag:W/"1766942073771"
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server:nginx
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x-content-type-options:nosniff
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x-request-id:33894112-b14d-42c1-95fc-818fbeb67036
x-xss-protection:0

{"resourceType":"Bundle","id":"8f5f53cb-23ef-3bbb-94a0-fc6ae21ae84d","meta":{"lastUpdated":"2026-01-30T19:31:36.774+01:00","tag":[{"system":"http://terminology.hl7.org/CodeSystem/v3-ObservationValue","code":"SUBSETTED","display":"Resource encoded in summary mode"}]},"type":"searchset","total":1,"link":[{"relation":"self","url":"https://tx-nordics.fhir.org/fhir/r4/CodeSystem?_format=json&_summary=true&url=http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2Fmondo.owl"}],"entry":[{"fullUrl":"https://tx-nordics.fhir.org/fhir/r4/CodeSystem/0f5b48de-3ffa-4ade-a097-db7f30bb09b0","resource":{"resourceType":"CodeSystem","id":"0f5b48de-3ffa-4ade-a097-db7f30bb09b0","meta":{"versionId":"1","lastUpdated":"2025-10-26T18:16:32.547+01:00","tag":[{"system":"http://terminology.hl7.org/CodeSystem/v3-ObservationValue","code":"SUBSETTED","display":"Resource encoded in summary mode"}]},"url":"http://purl.obolibrary.org/obo/mondo.owl","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.3.9216"}],"version":"1.0.0","name":"MONDO","title":"Mondo Disease Ontology","status":"active","experimental":false,"date":"2022-11-18T00:00:00-00:00","publisher":"The Monarch Initiative","contact":[{"name":"The Monarch Initiative; Nicole Vasilevsky","telecom":[{"system":"url","value":"http://monarchinitiatve.org/"},{"system":"email","value":"nicole@tislab.org"}]}],"caseSensitive":true,"content":"not-present"}}]}

#376

GET https://tx-nordics.fhir.org/fhir/r4/CodeSystem/0f5b48de-3ffa-4ade-a097-db7f30bb09b0 HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
User-Agent: fhir/publisher

200
cache-control:no-cache
content-location:https://tx-nordics.fhir.org/fhir/r4/CodeSystem/0f5b48de-3ffa-4ade-a097-db7f30bb09b0/_history/1
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:31:37 GMT
etag:W/"1"
last-modified:Sun, 26 Oct 2025 17:16:32 GMT
server:nginx
vary:Origin
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vary:Access-Control-Request-Headers
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x-content-type-options:nosniff
x-correlation-id:99992355-6998-4bd9-98ab-107e884e0408
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x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:99992355-6998-4bd9-98ab-107e884e0408
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{"resourceType":"CodeSystem","id":"0f5b48de-3ffa-4ade-a097-db7f30bb09b0","meta":{"versionId":"1","lastUpdated":"2025-10-26T18:16:32.547+01:00"},"text":{"status":"generated","div":"<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: CodeSystem MONDO</b></p><a name=\"MONDO\"/><a name=\"hcMONDO\"/><p>This case-sensitive code system <code>http://purl.obolibrary.org/obo/mondo.owl</code> defines codes, but no codes are represented here</p></div>"},"url":"http://purl.obolibrary.org/obo/mondo.owl","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.3.9216"}],"version":"1.0.0","name":"MONDO","title":"Mondo Disease Ontology","status":"active","experimental":false,"date":"2022-11-18T00:00:00-00:00","publisher":"The Monarch Initiative","contact":[{"name":"The Monarch Initiative; Nicole Vasilevsky","telecom":[{"system":"url","value":"http://monarchinitiatve.org/"},{"system":"email","value":"nicole@tislab.org"}]}],"description":"The Mondo Disease Ontology is a semi-automatically constructed ontology that merges in multiple disease resources to yield a coherent merged ontology that contains cross-species disease terminology.\r\n\r\nNumerous sources for disease definitions and data models currently exist, which include HPO, OMIM, SNOMED CT, ICD, PhenoDB, MedDRA, MedGen, ORDO, DO, GARD, etc; however, these sources partially overlap and sometimes conflict, making it difficult to know definitively how they relate to each other. This has resulted in a proliferation of mappings between disease entries in different resources; however mappings are problematic: collectively, they are expensive to create and maintain. Most importantly, the mappings lack completeness, accuracy, and precision; as a result, mapping calls are often inconsistent between resources. The UMLS provides intermediate concepts through which other resources can be mapped, but these mappings suffer from the same challenges: they are not guaranteed to be one-to-one, especially in areas with evolving disease concepts such as rare disease.\r\n\r\nIn order to address the lack of a unified disease terminology that provides precise equivalences between disease concepts, we created Mondo, which provides a logic-based structure for unifying multiple disease resources.\r\n\r\nMondo’s development is coordinated with the Human Phenotype Ontology (HPO), which describes the individual phenotypic features that constitute a disease. Like the HPO, Mondo provides a hierarchical structure which can be used for classification or “rolling up” diseases to higher level groupings. It provides mappings to other disease resources, but in contrast to other mappings between ontologies, we precisely annotate each mapping using strict semantics, so that we know when two disease names or identifiers are equivalent or one-to-one, in contrast to simply being closely related.\r\n\r\nFor more information, see [https://mondo.monarchinitiative.org/](https://mondo.monarchinitiative.org/)","copyright":"Copyrights permitted under terms specified by [Creative Commons Attribution 4.0 International (CC BY 4.0) ](https://creativecommons.org/licenses/by/4.0/legalcode).\r\n\r\nConsistent with the terms of CC BY 4.0, HL7 is permitted to  share, copy and redistribute the material in any medium or format and adapt, remix, transform, and build upon the material for its purposes as long as the CC BY 4.0 license terms are upheld.  HL7 must must give appropriate credit, provide a link to the license, and indicate if changes were made. HL7 may do so in any reasonable manner, but not in any way that suggests the licensor endorses HL7 or it's use. And HL7 may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.","caseSensitive":true,"content":"not-present"}

#377

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://purl.obolibrary.org/obo/mondo.owl","code":"MONDO:0012624","display":"acyl-CoA dehydrogenase 9 deficiency"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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date:Fri, 30 Jan 2026 18:31:37 GMT
server:nginx
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vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:29df4b91-fe71-427e-af98-a74b2c086cff
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x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:29df4b91-fe71-427e-af98-a74b2c086cff
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"MONDO:0012624"},{"name":"system","valueUri":"http://purl.obolibrary.org/obo/mondo.owl"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://purl.obolibrary.org/obo/mondo.owl was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://purl.obolibrary.org/obo/mondo.owl' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://purl.obolibrary.org/obo/mondo.owl"},{"name":"message","valueString":"A definition for CodeSystem 'http://purl.obolibrary.org/obo/mondo.owl' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://purl.obolibrary.org/obo/mondo.owl was not found"}]}

#378

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","code":"31934","display":"NM_000106.5(CYP2D6):c.886C>T (p.Arg296Cys)"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:31:38 GMT
server:nginx
vary:Origin
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vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:27ab319b-db8d-4a92-967b-62fb74662599
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x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:27ab319b-db8d-4a92-967b-62fb74662599
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"31934"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/clinvar"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/clinvar was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/clinvar"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/clinvar was not found"}]}

#379

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_000106.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:31:38 GMT
server:nginx
vary:Origin
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vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:188c5f8a-b7b7-4bcb-9154-3a75829b0e81
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x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:188c5f8a-b7b7-4bcb-9154-3a75829b0e81
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NM_000106.5"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#380

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000106.5:c.886C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:820
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:31:39 GMT
last-modified:Fri, 30 Jan 2026 18:31:39 GMT
pragma:no-cache
server:nginx
x-request-id:253-23571913

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000106.5:c.886C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000106.5:c.886C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_000106.5:c.886C>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_000106.5:c.886C>T\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#381

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_000097.3:p.Arg296Cys"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:832
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:31:39 GMT
last-modified:Fri, 30 Jan 2026 18:31:39 GMT
pragma:no-cache
server:nginx
x-request-id:253-23571917

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_000097.3:p.Arg296Cys"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_000097.3:p.Arg296Cys"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"()\"\r\n16 0    : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_000097.3:p.Arg296Cys (\"\")]\"\r\n16 0    : 0ms  : Check \"http://varnomen.hgvs.org#NP_000097.3:p.Arg296Cys\"\r\n16 0    : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#382

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000106.5:c.886C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1121
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:31:39 GMT
last-modified:Fri, 30 Jan 2026 18:31:39 GMT
pragma:no-cache
server:nginx
x-request-id:253-23571922

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000106.5:c.886C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000106.5:c.886C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_000106.5:c.886C>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_000106.5:c.886C>T\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n78 78   : 78ms : Code \"NM_000106.5:c.886C>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#383

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_000097.3:p.Arg296Cys"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1136
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:31:39 GMT
last-modified:Fri, 30 Jan 2026 18:31:39 GMT
pragma:no-cache
server:nginx
x-request-id:253-23571925

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_000097.3:p.Arg296Cys"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_000097.3:p.Arg296Cys"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_000097.3:p.Arg296Cys (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_000097.3:p.Arg296Cys\"\r\n16 16   : 16ms : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n16 0    : 16ms : check code in (http://varnomen.hgvs.org) at Coding\r\n79 63   : 79ms : Code \"NP_000097.3:p.Arg296Cys\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#384

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","code":"38486","display":"NM_000106.5(CYP2D6):c.1457G>C (p.Ser486Thr)"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:31:40 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:ec1d7734-adbf-44e9-ac05-558210d9fd6f
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:ec1d7734-adbf-44e9-ac05-558210d9fd6f
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"38486"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/clinvar"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/clinvar was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/clinvar"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/clinvar was not found"}]}

#385

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000106.5:c.1457G>C"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:824
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:31:40 GMT
last-modified:Fri, 30 Jan 2026 18:31:40 GMT
pragma:no-cache
server:nginx
x-request-id:253-23571933

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000106.5:c.1457G>C"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000106.5:c.1457G>C"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_000106.5:c.1457G>C (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_000106.5:c.1457G>C\"\r\n16 16   : 16ms : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#386

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000106.5:c.1457G>C"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1126
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:31:40 GMT
last-modified:Fri, 30 Jan 2026 18:31:40 GMT
pragma:no-cache
server:nginx
x-request-id:253-23571937

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000106.5:c.1457G>C"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000106.5:c.1457G>C"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_000106.5:c.1457G>C (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_000106.5:c.1457G>C\"\r\n16 16   : 16ms : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n16 0    : 16ms : check code in (http://varnomen.hgvs.org) at Coding\r\n78 62   : 78ms : Code \"NM_000106.5:c.1457G>C\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#387

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"293498008","display":"Debrisoquine adverse reaction (disorder)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1121
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:31:40 GMT
last-modified:Fri, 30 Jan 2026 18:31:40 GMT
pragma:no-cache
server:nginx
x-request-id:253-23571939

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "293498008"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Debrisoquine adverse reaction"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "293498008","display" : "Debrisoquine adverse reaction (disorder)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://snomed.info/sct#293498008 (\"Debrisoquine adverse reaction (disorder)\")]\"\r\n0 0     : 0ms  : Check \"http://snomed.info/sct#293498008\"\r\n16 16   : 16ms : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#388

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26423-6","display":"Increase dose"}],"text":"May need higher dosage than usual."}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL4049-4","name":"LOINCAnswersLL4049-4","title":"LOINC Answer Codes for LL4049-4","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL4049-4"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1242
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:31:42 GMT
last-modified:Fri, 30 Jan 2026 18:31:42 GMT
pragma:no-cache
server:nginx
x-request-id:253-23571941

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26423-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Increase dose"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26423-6","display" : "Increase dose"}],"text" : "May need higher dosage than usual."}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://loinc.org/vs/LL4049-4 for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL4049-4)\"\r\n16 0    : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n16 0    : 0ms  : Validate \"[http://loinc.org#LA26423-6 (\"Increase dose\")]\"\r\n16 0    : 0ms  : Check \"http://loinc.org#LA26423-6\"\r\n16 0    : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0    : 0ms  : check code in (http://loinc.org)(LIST=LL4049-4) at CodeableConcept.coding[0]\r\n2016 2000: 2000ms : Filter \"LIST=LL4049-4\": Code \"LA26423-6\" found in http://loinc.org|2.81\r\n"}]}

#389

GET https://tx-nordics.fhir.org/fhir/r4/CodeSystem?_format=json&url=http%3A%2F%2Fwww.pharmvar.org HTTP/1.0
User-Agent: hapi-fhir-tooling-client
Accept: application/fhir+json; fhirVersion=4.0

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:31:43 GMT
etag:W/"1769482885160"
last-modified:Fri, 30 Jan 2026 18:31:43 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:1e307c75-ff7e-4c72-9ef6-147464360771
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:1e307c75-ff7e-4c72-9ef6-147464360771
x-xss-protection:0

{"resourceType":"Bundle","id":"f1182517-9413-3a02-aec2-c3926585a761","meta":{"lastUpdated":"2026-01-30T19:31:43.389+01:00","tag":[{"system":"http://terminology.hl7.org/CodeSystem/v3-ObservationValue","code":"SUBSETTED","display":"Resource encoded in summary mode"}]},"type":"searchset","total":1,"link":[{"relation":"self","url":"https://tx-nordics.fhir.org/fhir/r4/CodeSystem?_format=json&_summary=true&url=http%3A%2F%2Fwww.pharmvar.org"}],"entry":[{"fullUrl":"https://tx-nordics.fhir.org/fhir/r4/CodeSystem/8196695a-d0f0-454e-aee8-ba4fdc57ea93","resource":{"resourceType":"CodeSystem","id":"8196695a-d0f0-454e-aee8-ba4fdc57ea93","meta":{"versionId":"1","lastUpdated":"2025-10-26T18:16:34.031+01:00","tag":[{"system":"http://terminology.hl7.org/CodeSystem/v3-ObservationValue","code":"SUBSETTED","display":"Resource encoded in summary mode"}]},"url":"http://www.pharmvar.org","version":"1.0.0","name":"PharmVar","title":"Pharmacogene Variation","status":"active","experimental":false,"date":"2024-04-29T00:00:00-00:00","publisher":"Pharmacogene Variation Consortium","contact":[{"name":"Pharmacogene Variation Consortium","telecom":[{"system":"url","value":"https://www.pharmvar.org/"},{"system":"email","value":"submissions@PharmVar.org"}]}],"caseSensitive":true,"content":"not-present"}}]}

#390

GET https://tx-nordics.fhir.org/fhir/r4/CodeSystem/8196695a-d0f0-454e-aee8-ba4fdc57ea93 HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
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200
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content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:31:43 GMT
etag:W/"1"
last-modified:Sun, 26 Oct 2025 17:16:34 GMT
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{"resourceType":"CodeSystem","id":"8196695a-d0f0-454e-aee8-ba4fdc57ea93","meta":{"versionId":"1","lastUpdated":"2025-10-26T18:16:34.031+01:00"},"text":{"status":"generated","div":"<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: CodeSystem PharmVar</b></p><a name=\"PharmVar\"/><a name=\"hcPharmVar\"/><p>This case-sensitive code system <code>http://www.pharmvar.org</code> defines codes, but no codes are represented here</p></div>"},"url":"http://www.pharmvar.org","version":"1.0.0","name":"PharmVar","title":"Pharmacogene Variation","status":"active","experimental":false,"date":"2024-04-29T00:00:00-00:00","publisher":"Pharmacogene Variation Consortium","contact":[{"name":"Pharmacogene Variation Consortium","telecom":[{"system":"url","value":"https://www.pharmvar.org/"},{"system":"email","value":"submissions@PharmVar.org"}]}],"description":"\"The major focus of the Pharmacogene Consortium (PharmVar) is to serve as a repository for allelic variation, providing an official and unified allele designation system for the Pharmacogenetics (PGx) community and facilitating the translation of genotype into phenotype and clinical implementation of PGx. While the majority of pharmacogenes in PharmVar utilize the star nomenclature to describe variation, the provision of single nucleotide variants (SNVs), rather than haplotype, is preferred for some genes. Thus, PharmVar has two different page formats, A) using star nomenclature and B) using rs ID# as allele (referred to as ‘rs-format’).\r\n\r\nPharmVar designates human pharmacogene variation and houses allelic variants in the PharmVar database.\r\n\r\n* All submissions to PharmVar must use the submission form available on [www.PharmVar.org](https://www.pharmvar.org/) and be submitted to [submissions@PharmVar.org](mailto:submissions@PharmVar.org). Only complete submission requests will be accepted and processed.\r\n\r\n* PharmVar Gene Expert Panels will review each submission and make a recommendation to the PharmVar Steering Committee.\r\n\r\n* In this ‘Allele Designation Criteria and Evidence level’ document, we collectively refer to deviations from the RefSeq as “sequence variations” or \"SNVs\", including single nucleotide polymorphisms (SNPs) and small nucleotide insertions and deletions (indels) up to 50 bp. Copy number variants (i.e. entire or partial gene deletions and duplications), hybrid genes (e.g. CYP2D6/2D7 hybrids) and duplications containing non-identical gene copies (e.g. CYP2D6\\*36+\\*10) are referred to as CNVs or structural variants.\r\n\r\n* PharmVar applies the following criteria for allele designation. In rare cases, exceptions may be made to accommodate established star allele definitions to minimize impact on research, clinical labs and/or PGx implementation.\"\r\n\r\nPharmVar is released monthly (or more frequently) and uses a numbered database version format for each release.\r\n\r\nNote on updates to variants: The variants defined in association with a given PharmVar ID are immutable. When it is necessary to update the variant definitions for an associated concept, the existing allele and PharmVar ID are marked as \"retired\" and a new PharmVar ID is issued with the updated variant definitions.\r\n\r\nIn the context of the representation of PharmVar in HL7 standards:\r\n\r\n* The concept identifier is the PharmVar ID\r\n\r\n* The concept display name is the Allele Name\r\n\r\n* There are several concept properties associated with PharmVar concepts (Legacy Label, Variants, etc.)\r\n\r\n* The code system is represented with an is-a hierarchy","copyright":"The PharmVar database content is licensed under a [Creative Commons Attribution-ShareAlike 4.0 International license](https://creativecommons.org/licenses/by-sa/4.0/) that allows for the sharing and adaptation of our information with proper attribution.\r\n\r\nSee [https://www.pharmvar.org/terms-and-conditions](https://www.pharmvar.org/terms-and-conditions) for Terms and Conditions.","caseSensitive":true,"content":"not-present"}

#391

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"CYP2C9*2*5\"","display":"CYP2C9 *2/*5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"CYP2C9*2*5\""},{"name":"system","valueUri":"http://www.pharmvar.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.pharmvar.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.pharmvar.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.pharmvar.org was not found"}]}

#392

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"CYP2C9*2*5\""},{"name":"system","valueUri":"http://www.pharmvar.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.pharmvar.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.pharmvar.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.pharmvar.org was not found"}]}

#393

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","code":"*2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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date:Fri, 30 Jan 2026 18:31:45 GMT
last-modified:Fri, 30 Jan 2026 18:31:45 GMT
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#394

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:2623","display":"CYP2C9"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:2623"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#395

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:2623"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:2623"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}]}

#396

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:2623","display":"CYP2C9"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:2623"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#397

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:23663","display":"VKORC1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:23663"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#398

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:23663"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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date:Fri, 30 Jan 2026 18:31:47 GMT
server:nginx
vary:Origin
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x-content-type-options:nosniff
x-correlation-id:c5a23c4f-9776-4766-bf51-24b8839b6be5
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x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:c5a23c4f-9776-4766-bf51-24b8839b6be5
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:23663"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}]}

#399

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:23663","display":"VKORC1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
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date:Fri, 30 Jan 2026 18:31:48 GMT
server:nginx
vary:Origin
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:23663"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#400

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://www.nlm.nih.gov/research/umls/rxnorm","code":"11289","display":"Warfarin"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1013
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:31:48 GMT
last-modified:Fri, 30 Jan 2026 18:31:48 GMT
pragma:no-cache
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x-request-id:253-23572024

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://www.nlm.nih.gov/research/umls/rxnorm"},{"name" : "code","valueCode" : "11289"},{"name" : "version","valueString" : "??"},{"name" : "display","valueString" : "warfarin"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://www.nlm.nih.gov/research/umls/rxnorm","code" : "11289","display" : "Warfarin"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.nlm.nih.gov/research/umls/rxnorm#11289 (\"Warfarin\")]\"\r\n0 0     : 0ms  : Check \"http://www.nlm.nih.gov/research/umls/rxnorm#11289\"\r\n0 0     : 0ms  : Using CodeSystem \"http://www.nlm.nih.gov/research/umls/rxnorm|??\" (content = complete)\r\n"}]}

#401

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA25390-8","display":"Rapid metabolizer"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"genetic-therapeutic-implications-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs","version":"4.0.0-cibuild","name":"GeneticTherapeuticImplicationsVS","title":"Genetic Therapeutic Implications","status":"active","experimental":false,"date":"2026-01-30T18:21:39+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for terms that describe a predicted ramification based on the presence of associated molecular finding(s).","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This material contains content from LOINC (http://loinc.org). LOINC is copyright © 1995-2020, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC® is a registered United States trademark of Regenstrief Institute, Inc.\nThis value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement.","compose":{"include":[{"system":"http://loinc.org","concept":[{"code":"LA10315-2","display":"Ultrarapid metabolizer"},{"code":"LA25391-6","display":"Normal metabolizer"},{"code":"LA25390-8","display":"Rapid metabolizer"},{"code":"LA10317-8","display":"Intermediate metabolizer"},{"code":"LA9657-3","display":"Poor metabolizer"},{"code":"LA19542-2","display":"Low Risk"},{"code":"LA19541-4","display":"High Risk"},{"code":"LA6676-6","display":"Resistant"},{"code":"LA6677-4","display":"Responsive"},{"code":"LA9660-7","display":"Presumed resistant"},{"code":"LA9661-5","display":"Presumed responsive"},{"code":"LA6682-4","display":"Unknown Significance"},{"code":"LA6675-8","display":"Benign"},{"code":"LA6674-1","display":"Presumed Benign"},{"code":"LA9662-3","display":"Presumed non-responsive"},{"code":"LA25392-4","display":"Increased function"},{"code":"LA25393-2","display":"Normal function"},{"code":"LA25395-7","display":"Decreased function"},{"code":"LA25394-0","display":"Poor function"}]},{"system":"http://snomed.info/sct","concept":[{"code":"444734003","display":"Does not meet eligibility criteria for clinical trial (finding)"},{"code":"399223003","display":"Patient eligible for clinical trial (finding)"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1796
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:31:48 GMT
last-modified:Fri, 30 Jan 2026 18:31:48 GMT
pragma:no-cache
server:nginx
x-request-id:253-23572026

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA25390-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Rapid metabolizer"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA25390-8","display" : "Rapid metabolizer"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15   : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-cibuild for validation purposes\r\n15 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n15 0    : 0ms  : Prepare include: \"(http://loinc.org)(LA10315-2,LA25391-6,LA25390-8,LA10317-8,LA9657-3,LA19542-2,LA19541-4,LA6676-6,LA6677-4,LA9660-7,LA9661-5,LA6682-4,LA6675-8,LA6674-1,LA9662-3,LA25392-4,LA25393-2,LA25395-7,LA25394-0)\"\r\n15 0    : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n15 0    : 0ms  : Prepare include: \"(http://snomed.info/sct)(444734003,399223003)\"\r\n15 0    : 0ms  : CodeSystem found: \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\"\r\n15 0    : 0ms  : Validate \"[http://loinc.org#LA25390-8 (\"Rapid metabolizer\")]\"\r\n15 0    : 0ms  : Check \"http://loinc.org#LA25390-8\"\r\n15 0    : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n15 0    : 0ms  : check code in (http://loinc.org)(LA10315-2,LA25391-6,LA25390-8,LA10317-8,LA9657-3,LA19542-2,LA19541-4,LA6676-6,LA6677-4,LA9660-7,LA9661-5,LA6682-4,LA6675-8,LA6674-1,LA9662-3,LA25392-4,LA25393-2,LA25395-7,LA25394-0) at CodeableConcept.coding[0]\r\n15 0    : 0ms  : Code \"LA25390-8\" found in http://loinc.org|2.81\r\n"}]}

#402

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA25390-8","display":"Rapid metabolizer"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:925
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:31:50 GMT
last-modified:Fri, 30 Jan 2026 18:31:50 GMT
pragma:no-cache
server:nginx
x-request-id:253-23572028

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA25390-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Rapid metabolizer"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA25390-8","display" : "Rapid metabolizer"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA25390-8 (\"Rapid metabolizer\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA25390-8\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#403

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26423-6","display":"Increase dose"}],"text":"May need higher dosage than usual."}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL1037-2","name":"LOINCAnswersLL1037-2","title":"LOINC Answer Codes for LL1037-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL1037-2"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2263
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:31:52 GMT
last-modified:Fri, 30 Jan 2026 18:31:52 GMT
pragma:no-cache
server:nginx
x-request-id:253-23572039

{"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1037-2'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26423-6","display" : "Increase dose"}],"text" : "May need higher dosage than usual."}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA26423-6 ('Increase dose')' was not found in the value set 'http://loinc.org/vs/LL1037-2'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1037-2'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL1037-2 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL1037-2)\"\r\n16 16   : 16ms : CodeSystem found: \"http://loinc.org|2.81\"\r\n16 0    : 16ms : Validate \"[http://loinc.org#LA26423-6 (\"Increase dose\")]\"\r\n16 0    : 16ms : Check \"http://loinc.org#LA26423-6\"\r\n16 0    : 16ms : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0    : 16ms : check code in (http://loinc.org)(LIST=LL1037-2) at CodeableConcept.coding[0]\r\n2032 2016: 2032ms : Filter \"LIST=LL1037-2\": Code \"LA26423-6\" not found in http://loinc.org|2.81\r\n"}]}

#404

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6676-6","display":"Resistant"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:897
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:31:53 GMT
last-modified:Fri, 30 Jan 2026 18:31:53 GMT
pragma:no-cache
server:nginx
x-request-id:253-23572056

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6676-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Resistant"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6676-6","display" : "Resistant"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA6676-6 (\"Resistant\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA6676-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#405

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6676-6","display":"Resistant"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"genetic-therapeutic-implications-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs","version":"4.0.0-cibuild","name":"GeneticTherapeuticImplicationsVS","title":"Genetic Therapeutic Implications","status":"active","experimental":false,"date":"2026-01-30T18:21:39+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for terms that describe a predicted ramification based on the presence of associated molecular finding(s).","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This material contains content from LOINC (http://loinc.org). LOINC is copyright © 1995-2020, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC® is a registered United States trademark of Regenstrief Institute, Inc.\nThis value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement.","compose":{"include":[{"system":"http://loinc.org","concept":[{"code":"LA10315-2","display":"Ultrarapid metabolizer"},{"code":"LA25391-6","display":"Normal metabolizer"},{"code":"LA25390-8","display":"Rapid metabolizer"},{"code":"LA10317-8","display":"Intermediate metabolizer"},{"code":"LA9657-3","display":"Poor metabolizer"},{"code":"LA19542-2","display":"Low Risk"},{"code":"LA19541-4","display":"High Risk"},{"code":"LA6676-6","display":"Resistant"},{"code":"LA6677-4","display":"Responsive"},{"code":"LA9660-7","display":"Presumed resistant"},{"code":"LA9661-5","display":"Presumed responsive"},{"code":"LA6682-4","display":"Unknown Significance"},{"code":"LA6675-8","display":"Benign"},{"code":"LA6674-1","display":"Presumed Benign"},{"code":"LA9662-3","display":"Presumed non-responsive"},{"code":"LA25392-4","display":"Increased function"},{"code":"LA25393-2","display":"Normal function"},{"code":"LA25395-7","display":"Decreased function"},{"code":"LA25394-0","display":"Poor function"}]},{"system":"http://snomed.info/sct","concept":[{"code":"444734003","display":"Does not meet eligibility criteria for clinical trial (finding)"},{"code":"399223003","display":"Patient eligible for clinical trial (finding)"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1767
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:31:53 GMT
last-modified:Fri, 30 Jan 2026 18:31:53 GMT
pragma:no-cache
server:nginx
x-request-id:253-23572073

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6676-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Resistant"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6676-6","display" : "Resistant"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-cibuild for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"(http://loinc.org)(LA10315-2,LA25391-6,LA25390-8,LA10317-8,LA9657-3,LA19542-2,LA19541-4,LA6676-6,LA6677-4,LA9660-7,LA9661-5,LA6682-4,LA6675-8,LA6674-1,LA9662-3,LA25392-4,LA25393-2,LA25395-7,LA25394-0)\"\r\n16 0    : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n16 0    : 0ms  : Prepare include: \"(http://snomed.info/sct)(444734003,399223003)\"\r\n16 0    : 0ms  : CodeSystem found: \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\"\r\n16 0    : 0ms  : Validate \"[http://loinc.org#LA6676-6 (\"Resistant\")]\"\r\n16 0    : 0ms  : Check \"http://loinc.org#LA6676-6\"\r\n16 0    : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0    : 0ms  : check code in (http://loinc.org)(LA10315-2,LA25391-6,LA25390-8,LA10317-8,LA9657-3,LA19542-2,LA19541-4,LA6676-6,LA6677-4,LA9660-7,LA9661-5,LA6682-4,LA6675-8,LA6674-1,LA9662-3,LA25392-4,LA25393-2,LA25395-7,LA25394-0) at CodeableConcept.coding[0]\r\n16 0    : 0ms  : Code \"LA6676-6\" found in http://loinc.org|2.81\r\n"}]}

#406

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6576-8","display":"Positive"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:894
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:31:55 GMT
last-modified:Fri, 30 Jan 2026 18:31:55 GMT
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x-request-id:253-23572074

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6576-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Positive"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6576-8","display" : "Positive"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA6576-8 (\"Positive\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA6576-8\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#407

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"10828004","display":"Positive"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1032
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:31:55 GMT
last-modified:Fri, 30 Jan 2026 18:31:55 GMT
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x-request-id:253-23572091

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "10828004"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Positive"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "10828004","display" : "Positive"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://snomed.info/sct#10828004 (\"Positive\")]\"\r\n0 0     : 0ms  : Check \"http://snomed.info/sct#10828004\"\r\n0 0     : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#408

GET https://tx.fhir.org/r4/CodeSystem?_format=json&url=urn%3Aietf%3Abcp%3A13 HTTP/1.0
User-Agent: hapi-fhir-tooling-client
Accept: application/fhir+json; fhirVersion=4.0

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:233
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:31:55 GMT
pragma:no-cache
server:nginx
x-request-id:253-23572094

{"resourceType" : "Bundle","id" : "42ff7db4-31ac-4227-a7db-1c16aae35e","meta" : {"lastUpdated" : "2026-01-30T18:31:55.380Z"},"type" : "searchset","total" : 0,"link" : [{"relation" : "self","url" : "CodeSystem?&url=urn:ietf:bcp:13"}]}

#409

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"inferSystem","valueBoolean":true},{"name":"code","valueCode":"text/plain"},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"urn:uuid:519b1c56-4846-49cb-97da-b957d0101de5","status":"active","compose":{"include":[{"system":"urn:ietf:bcp:13"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-length:951
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:31:55 GMT
last-modified:Fri, 30 Jan 2026 18:31:55 GMT
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x-request-id:253-23572096

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "urn:ietf:bcp:13"},{"name" : "code","valueCode" : "text/plain"},{"name" : "display","valueString" : "text/plain"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing urn:uuid:519b1c56-4846-49cb-97da-b957d0101de5 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(urn:ietf:bcp:13)\"\r\n0 0     : 0ms  : CodeSystem found: \"urn:ietf:bcp:13|\"\r\n0 0     : 0ms  : Validate \"[#text/plain (\"\")]\" and infer system\r\n0 0     : 0ms  : Check \"#text/plain\"\r\n0 0     : 0ms  : Inferred CodeSystem = \"urn:ietf:bcp:13\"\r\n16 16   : 16ms : CodeSystem found: urn:ietf:bcp:13| for urn:ietf:bcp:13\r\n16 0    : 16ms : check code in (urn:ietf:bcp:13) at \r\n16 0    : 16ms : Code \"text/plain\" found in urn:ietf:bcp:13|\r\n"}]}

#410

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"inferSystem","valueBoolean":true},{"name":"code","valueCode":"text/plain"},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"mimetypes","meta":{"lastUpdated":"2019-11-01T09:29:23.356+11:00","profile":["http://hl7.org/fhir/StructureDefinition/shareablevalueset"]},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"fhir"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"normative"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version","valueCode":"4.0.0"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":5}],"url":"http://hl7.org/fhir/ValueSet/mimetypes","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.1024"}],"version":"4.0.1","name":"Mime Types","title":"MimeType","status":"active","experimental":false,"date":"2019-11-01T09:29:23+11:00","publisher":"HL7 International - FHIR-Infrastructure","contact":[{"telecom":[{"system":"url","value":"http://hl7.org/fhir"}]}],"description":"This value set includes all possible codes from BCP-13 (http://tools.ietf.org/html/bcp13)","compose":{"include":[{"system":"urn:ietf:bcp:13"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:950
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:31:55 GMT
last-modified:Fri, 30 Jan 2026 18:31:55 GMT
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x-request-id:253-23572098

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "urn:ietf:bcp:13"},{"name" : "code","valueCode" : "text/plain"},{"name" : "display","valueString" : "text/plain"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/mimetypes|4.0.1 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(urn:ietf:bcp:13)\"\r\n0 0     : 0ms  : CodeSystem found: \"urn:ietf:bcp:13|\"\r\n0 0     : 0ms  : Validate \"[#text/plain (\"\")]\" and infer system\r\n0 0     : 0ms  : Check \"#text/plain\"\r\n0 0     : 0ms  : Inferred CodeSystem = \"urn:ietf:bcp:13\"\r\n16 16   : 16ms : CodeSystem found: urn:ietf:bcp:13| for urn:ietf:bcp:13\r\n16 0    : 16ms : check code in (urn:ietf:bcp:13) at \r\n16 0    : 16ms : Code \"text/plain\" found in urn:ietf:bcp:13|\r\n"}]}

#411

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"CYP2C9*2*5\"","display":"CYP2C9 *2/*5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:31:56 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:90859862-0b35-4adc-bb13-0b19aa96e640
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:90859862-0b35-4adc-bb13-0b19aa96e640
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"CYP2C9*2*5\""},{"name":"system","valueUri":"http://www.pharmvar.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.pharmvar.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.pharmvar.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.pharmvar.org was not found"}]}

#412

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA19542-2","display":"Low risk"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:898
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:31:58 GMT
last-modified:Fri, 30 Jan 2026 18:31:58 GMT
pragma:no-cache
server:nginx
x-request-id:253-23572113

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA19542-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Low risk"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA19542-2","display" : "Low risk"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA19542-2 (\"Low risk\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA19542-2\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#413

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA19542-2","display":"Low risk"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"genetic-therapeutic-implications-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs","version":"4.0.0-cibuild","name":"GeneticTherapeuticImplicationsVS","title":"Genetic Therapeutic Implications","status":"active","experimental":false,"date":"2026-01-30T18:21:39+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for terms that describe a predicted ramification based on the presence of associated molecular finding(s).","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This material contains content from LOINC (http://loinc.org). LOINC is copyright © 1995-2020, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC® is a registered United States trademark of Regenstrief Institute, Inc.\nThis value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement.","compose":{"include":[{"system":"http://loinc.org","concept":[{"code":"LA10315-2","display":"Ultrarapid metabolizer"},{"code":"LA25391-6","display":"Normal metabolizer"},{"code":"LA25390-8","display":"Rapid metabolizer"},{"code":"LA10317-8","display":"Intermediate metabolizer"},{"code":"LA9657-3","display":"Poor metabolizer"},{"code":"LA19542-2","display":"Low Risk"},{"code":"LA19541-4","display":"High Risk"},{"code":"LA6676-6","display":"Resistant"},{"code":"LA6677-4","display":"Responsive"},{"code":"LA9660-7","display":"Presumed resistant"},{"code":"LA9661-5","display":"Presumed responsive"},{"code":"LA6682-4","display":"Unknown Significance"},{"code":"LA6675-8","display":"Benign"},{"code":"LA6674-1","display":"Presumed Benign"},{"code":"LA9662-3","display":"Presumed non-responsive"},{"code":"LA25392-4","display":"Increased function"},{"code":"LA25393-2","display":"Normal function"},{"code":"LA25395-7","display":"Decreased function"},{"code":"LA25394-0","display":"Poor function"}]},{"system":"http://snomed.info/sct","concept":[{"code":"444734003","display":"Does not meet eligibility criteria for clinical trial (finding)"},{"code":"399223003","display":"Patient eligible for clinical trial (finding)"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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date:Fri, 30 Jan 2026 18:31:58 GMT
last-modified:Fri, 30 Jan 2026 18:31:58 GMT
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x-request-id:253-23572134

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA19542-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Low risk"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA19542-2","display" : "Low risk"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-cibuild for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"(http://loinc.org)(LA10315-2,LA25391-6,LA25390-8,LA10317-8,LA9657-3,LA19542-2,LA19541-4,LA6676-6,LA6677-4,LA9660-7,LA9661-5,LA6682-4,LA6675-8,LA6674-1,LA9662-3,LA25392-4,LA25393-2,LA25395-7,LA25394-0)\"\r\n16 0    : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n16 0    : 0ms  : Prepare include: \"(http://snomed.info/sct)(444734003,399223003)\"\r\n16 0    : 0ms  : CodeSystem found: \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\"\r\n16 0    : 0ms  : Validate \"[http://loinc.org#LA19542-2 (\"Low risk\")]\"\r\n16 0    : 0ms  : Check \"http://loinc.org#LA19542-2\"\r\n16 0    : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0    : 0ms  : check code in (http://loinc.org)(LA10315-2,LA25391-6,LA25390-8,LA10317-8,LA9657-3,LA19542-2,LA19541-4,LA6676-6,LA6677-4,LA9660-7,LA9661-5,LA6682-4,LA6675-8,LA6674-1,LA9662-3,LA25392-4,LA25393-2,LA25395-7,LA25394-0) at CodeableConcept.coding[0]\r\n16 0    : 0ms  : Code \"LA19542-2\" found in http://loinc.org|2.81\r\n"}]}

#414

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
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{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26423-6","display":"Increase dose"}],"text":"May need higher dosage than usual."}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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date:Fri, 30 Jan 2026 18:31:59 GMT
last-modified:Fri, 30 Jan 2026 18:31:59 GMT
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#415

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
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{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"51969-4"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"report-codes","meta":{"lastUpdated":"2019-11-01T09:29:23.356+11:00","profile":["http://hl7.org/fhir/StructureDefinition/shareablevalueset"]},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"oo"}],"url":"http://hl7.org/fhir/ValueSet/report-codes","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.233"}],"version":"4.0.1","name":"LOINCDiagnosticReportCodes","title":"LOINC Diagnostic Report Codes","status":"draft","experimental":false,"date":"2019-11-01T09:29:23+11:00","publisher":"FHIR Project team","contact":[{"telecom":[{"system":"url","value":"http://hl7.org/fhir"}]}],"description":"This value set includes LOINC codes that relate to Diagnostic Observations.","copyright":"This content from LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use.","compose":{"include":[{"system":"http://loinc.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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last-modified:Fri, 30 Jan 2026 18:31:59 GMT
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51969-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic analysis report"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "51969-4"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/report-codes|4.0.1 for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"(http://loinc.org)\"\r\n16 0    : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n16 0    : 0ms  : Validate \"[http://loinc.org#51969-4 (\"\")]\"\r\n16 0    : 0ms  : Check \"http://loinc.org#51969-4\"\r\n16 0    : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0    : 0ms  : check code in (http://loinc.org) at CodeableConcept.coding[0]\r\n16 0    : 0ms  : Code \"51969-4\" found in http://loinc.org|2.81\r\n"}]}

#416

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
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{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/projects/SNP","version":"137","code":"rs368949613"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"rs368949613"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name":"version","valueString":"137"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/projects/SNP|137 was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' version '137' could not be found, so the code cannot be validated. Valid versions: [2.0.1]"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/projects/SNP|137"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' version '137' could not be found, so the code cannot be validated. Valid versions: [2.0.1]; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/projects/SNP|137 was not found"}]}

#417

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81299-0"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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date:Fri, 30 Jan 2026 18:32:01 GMT
last-modified:Fri, 30 Jan 2026 18:32:01 GMT
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81299-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Structural variant reported arrCGH [Ratio]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81299-0"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81299-0 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81299-0\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#418

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81300-6"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:32:03 GMT
last-modified:Fri, 30 Jan 2026 18:32:03 GMT
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x-request-id:253-23572191

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81300-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Structural variant [Length]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81300-6"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81300-6 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81300-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#419

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","version":"???","code":"38486","display":"NM_000106.5(CYP2D6):c.1457G>C (p.Ser486Thr)"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"38486"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/clinvar"},{"name":"version","valueString":"???"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/clinvar|??? was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' version '???' could not be found, so the code cannot be validated. Valid versions: [1.0.1]"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/clinvar|???"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' version '???' could not be found, so the code cannot be validated. Valid versions: [1.0.1]; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/clinvar|??? was not found"}]}

#420

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
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User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"CYP2C9 *2/*5","display":"CYP2C9 *2/*5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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x-request-id:95551684-064f-439a-8d13-e30b0dbca232
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"CYP2C9 *2/*5"},{"name":"system","valueUri":"http://www.pharmvar.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.pharmvar.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.pharmvar.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.pharmvar.org was not found"}]}

#421

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"CYP2C9 *2/*5","display":"CYP2C9 *2/*5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:32:04 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:33cea077-ffb0-49a2-9239-e9bdbc58872c
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:33cea077-ffb0-49a2-9239-e9bdbc58872c
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"CYP2C9 *2/*5"},{"name":"system","valueUri":"http://www.pharmvar.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.pharmvar.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.pharmvar.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.pharmvar.org was not found"}]}

#422

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"CYP2C9 *2/*5","display":"CYP2C9 *2/*5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:32:05 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:e3cbe367-0086-40d9-b39d-2b9e3639eb91
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:e3cbe367-0086-40d9-b39d-2b9e3639eb91
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"CYP2C9 *2/*5"},{"name":"system","valueUri":"http://www.pharmvar.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.pharmvar.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.pharmvar.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.pharmvar.org was not found"}]}

#423

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"51958-7","display":"Transcript ref sequence ID"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:952
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:32:07 GMT
last-modified:Fri, 30 Jan 2026 18:32:07 GMT
pragma:no-cache
server:nginx
x-request-id:253-23572254

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51958-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Transcript reference sequence [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "51958-7","display" : "Transcript ref sequence ID"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#51958-7 (\"Transcript ref sequence ID\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#51958-7\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#424

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_022787.3","display":"NM_022787.3"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:32:08 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:5f1b15f6-7b82-4f7a-8157-f2b517700684
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:5f1b15f6-7b82-4f7a-8157-f2b517700684
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NM_022787.3"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#425

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"69547-8","display":"Genomic ref allele [ID]"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:935
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:32:09 GMT
last-modified:Fri, 30 Jan 2026 18:32:09 GMT
pragma:no-cache
server:nginx
x-request-id:253-23572291

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69547-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic ref allele [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "69547-8","display" : "Genomic ref allele [ID]"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#69547-8 (\"Genomic ref allele [ID]\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#69547-8\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#426

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"69551-0","display":"Genomic alt allele [ID]"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:935
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:32:11 GMT
last-modified:Fri, 30 Jan 2026 18:32:11 GMT
pragma:no-cache
server:nginx
x-request-id:253-23572312

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69551-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic alt allele [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "69551-0","display" : "Genomic alt allele [ID]"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#69551-0 (\"Genomic alt allele [ID]\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#69551-0\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#427

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","code":"RCV000664188.1","display":"NM_022787.3(NMNAT1):c.[53A>G];[769G>A] AND Cone-rod dystrophy"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:32:11 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:6b433c40-e3fb-49cf-aa63-b565aa84b0f5
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:6b433c40-e3fb-49cf-aa63-b565aa84b0f5
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"RCV000664188.1"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/clinvar"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/clinvar was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/clinvar"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/clinvar was not found"}]}

#428

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48004-6","display":"DNA change (c.HGVS)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:923
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:32:13 GMT
last-modified:Fri, 30 Jan 2026 18:32:13 GMT
pragma:no-cache
server:nginx
x-request-id:253-23572348

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48004-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "DNA change (c.HGVS)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48004-6","display" : "DNA change (c.HGVS)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48004-6 (\"DNA change (c.HGVS)\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48004-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#429

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_022787.3:c.769G>A","display":"NM_022787.3:c.769G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:840
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:32:13 GMT
last-modified:Fri, 30 Jan 2026 18:32:13 GMT
pragma:no-cache
server:nginx
x-request-id:253-23572367

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_022787.3:c.769G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_022787.3:c.769G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_022787.3:c.769G>A (\"NM_022787.3:c.769G>A\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_022787.3:c.769G>A\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#430

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_022787.3:c.769G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1121
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:32:13 GMT
last-modified:Fri, 30 Jan 2026 18:32:13 GMT
pragma:no-cache
server:nginx
x-request-id:253-23572371

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_022787.3:c.769G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_022787.3:c.769G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_022787.3:c.769G>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_022787.3:c.769G>A\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n78 78   : 78ms : Code \"NM_022787.3:c.769G>A\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#431

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_022787.3:c.53A>G","display":"NM_022787.3:c.53A>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:835
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:32:13 GMT
last-modified:Fri, 30 Jan 2026 18:32:13 GMT
pragma:no-cache
server:nginx
x-request-id:253-23572374

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_022787.3:c.53A>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_022787.3:c.53A>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_022787.3:c.53A>G (\"NM_022787.3:c.53A>G\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_022787.3:c.53A>G\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#432

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_022787.3:c.53A>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1116
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:32:13 GMT
last-modified:Fri, 30 Jan 2026 18:32:13 GMT
pragma:no-cache
server:nginx
x-request-id:253-23572379

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_022787.3:c.53A>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_022787.3:c.53A>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_022787.3:c.53A>G (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_022787.3:c.53A>G\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n63 63   : 63ms : Code \"NM_022787.3:c.53A>G\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#433

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"94076-7","display":"Mutations/Megabase [# Ratio] in Tumor"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:977
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:32:14 GMT
last-modified:Fri, 30 Jan 2026 18:32:14 GMT
pragma:no-cache
server:nginx
x-request-id:253-23572383

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "94076-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Mutations/Megabase [# Ratio] in Tumor"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "94076-7","display" : "Mutations/Megabase [# Ratio] in Tumor"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#94076-7 (\"Mutations/Megabase [# Ratio] in Tumor\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#94076-7\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#434

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26398-0","display":"Sequencing"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:904
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:32:16 GMT
last-modified:Fri, 30 Jan 2026 18:32:16 GMT
pragma:no-cache
server:nginx
x-request-id:253-23572394

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26398-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Sequencing"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26398-0","display" : "Sequencing"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA26398-0 (\"Sequencing\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA26398-0\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#435

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81290-9","display":"Genomic DNA change (gHGVS)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:944
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:32:17 GMT
last-modified:Fri, 30 Jan 2026 18:32:17 GMT
pragma:no-cache
server:nginx
x-request-id:253-23572419

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81290-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic DNA change (gHGVS)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81290-9","display" : "Genomic DNA change (gHGVS)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81290-9 (\"Genomic DNA change (gHGVS)\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81290-9\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#436

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000007.13:g.140453136A>T","display":"NC_000007.13:g.140453136A>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:875
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:32:17 GMT
last-modified:Fri, 30 Jan 2026 18:32:17 GMT
pragma:no-cache
server:nginx
x-request-id:253-23572441

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000007.13:g.140453136A>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000007.13:g.140453136A>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000007.13:g.140453136A>T (\"NC_000007.13:g.140453136A>T\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000007.13:g.140453136A>T\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#437

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","code":"13961","display":"Clinvar ID 13961"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:32:18 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:fef2984a-c968-48fe-99d4-853068a568c1
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:fef2984a-c968-48fe-99d4-853068a568c1
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"13961"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/clinvar"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/clinvar was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/clinvar"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/clinvar was not found"}]}

#438

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48005-3","display":"Amino acid change (pHGVS)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:941
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:32:19 GMT
last-modified:Fri, 30 Jan 2026 18:32:19 GMT
pragma:no-cache
server:nginx
x-request-id:253-23572455

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48005-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Amino acid change (pHGVS)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48005-3","display" : "Amino acid change (pHGVS)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48005-3 (\"Amino acid change (pHGVS)\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48005-3\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#439

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_004324.2:p.Val600Glu","display":"NP_004324.2:p.Val600Glu"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:855
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:32:19 GMT
last-modified:Fri, 30 Jan 2026 18:32:19 GMT
pragma:no-cache
server:nginx
x-request-id:253-23572483

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_004324.2:p.Val600Glu"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_004324.2:p.Val600Glu"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_004324.2:p.Val600Glu (\"NP_004324.2:p.Val600Glu\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_004324.2:p.Val600Glu\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#440

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48018-6","display":"Gene studied ID"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:913
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:32:21 GMT
last-modified:Fri, 30 Jan 2026 18:32:21 GMT
pragma:no-cache
server:nginx
x-request-id:253-23572486

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48018-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Gene studied [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48018-6","display" : "Gene studied ID"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48018-6 (\"Gene studied ID\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48018-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#441

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:1097","display":"BRAF"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:32:21 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:fb39cbad-32f9-40fa-b769-aac7fde1e9c6
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:fb39cbad-32f9-40fa-b769-aac7fde1e9c6
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:1097"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#442

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26398-0","display":"Sequencing"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL4048-6","name":"LOINCAnswersLL4048-6","title":"LOINC Answer Codes for LL4048-6","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL4048-6"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1187
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:32:23 GMT
last-modified:Fri, 30 Jan 2026 18:32:23 GMT
pragma:no-cache
server:nginx
x-request-id:253-23572519

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26398-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Sequencing"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26398-0","display" : "Sequencing"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL4048-6 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL4048-6)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA26398-0 (\"Sequencing\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA26398-0\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL4048-6) at CodeableConcept.coding[0]\r\n1985 1985: 1985ms : Filter \"LIST=LL4048-6\": Code \"LA26398-0\" found in http://loinc.org|2.81\r\n"}]}

#443

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000007.13:g.140453136A>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1156
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:32:24 GMT
last-modified:Fri, 30 Jan 2026 18:32:24 GMT
pragma:no-cache
server:nginx
x-request-id:253-23572554

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000007.13:g.140453136A>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000007.13:g.140453136A>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000007.13:g.140453136A>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000007.13:g.140453136A>T\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n78 78   : 78ms : Code \"NC_000007.13:g.140453136A>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#444

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_004324.2:p.Val600Glu"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1136
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:32:24 GMT
last-modified:Fri, 30 Jan 2026 18:32:24 GMT
pragma:no-cache
server:nginx
x-request-id:253-23572557

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_004324.2:p.Val600Glu"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_004324.2:p.Val600Glu"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_004324.2:p.Val600Glu (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_004324.2:p.Val600Glu\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n78 78   : 78ms : Code \"NP_004324.2:p.Val600Glu\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#445

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:1097","display":"BRAF"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:32:24 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:1e8af320-8aba-44b0-bf28-74b53c85dde1
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:1e8af320-8aba-44b0-bf28-74b53c85dde1
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:1097"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#446

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:1097"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:32:25 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:1e3464b5-a151-4483-8d0d-c619debbd287
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:1e3464b5-a151-4483-8d0d-c619debbd287
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:1097"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}]}

#447

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26811-2","display":"Computational analysis"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:940
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:32:26 GMT
last-modified:Fri, 30 Jan 2026 18:32:26 GMT
pragma:no-cache
server:nginx
x-request-id:253-23572580

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26811-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Computational analysis"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26811-2","display" : "Computational analysis"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA26811-2 (\"Computational analysis\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA26811-2\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#448

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"53037-8","display":"Genetic variation clinical significance [Imp]"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1001
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:32:28 GMT
last-modified:Fri, 30 Jan 2026 18:32:28 GMT
pragma:no-cache
server:nginx
x-request-id:253-23572602

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "53037-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic variation clinical significance [Imp]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "53037-8","display" : "Genetic variation clinical significance [Imp]"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#53037-8 (\"Genetic variation clinical significance [Imp]\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#53037-8\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#449

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"93044-6","display":"Level of Evidence"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:917
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:32:29 GMT
last-modified:Fri, 30 Jan 2026 18:32:29 GMT
pragma:no-cache
server:nginx
x-request-id:253-23572625

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "93044-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Level of evidence"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "93044-6","display" : "Level of Evidence"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#93044-6 (\"Level of Evidence\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#93044-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#450

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA30200-2","display":"Very strong evidence pathogenic"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:967
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:32:31 GMT
last-modified:Fri, 30 Jan 2026 18:32:31 GMT
pragma:no-cache
server:nginx
x-request-id:253-23572647

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA30200-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Very strong evidence pathogenic"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA30200-2","display" : "Very strong evidence pathogenic"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA30200-2 (\"Very strong evidence pathogenic\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA30200-2\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#451

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26398-0","display":"Sequencing"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL4050-2","name":"LOINCAnswersLL4050-2","title":"LOINC Answer Codes for LL4050-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL4050-2"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2208
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:32:32 GMT
last-modified:Fri, 30 Jan 2026 18:32:32 GMT
pragma:no-cache
server:nginx
x-request-id:253-23572671

{"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://loinc.org/vs/LL4050-2'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26398-0","display" : "Sequencing"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA26398-0 ('Sequencing')' was not found in the value set 'http://loinc.org/vs/LL4050-2'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://loinc.org/vs/LL4050-2'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL4050-2 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL4050-2)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA26398-0 (\"Sequencing\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA26398-0\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL4050-2) at CodeableConcept.coding[0]\r\n1016 1016: 1016ms : Filter \"LIST=LL4050-2\": Code \"LA26398-0\" not found in http://loinc.org|2.81\r\n"}]}

#452

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26811-2","display":"Computational analysis"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL4048-6","name":"LOINCAnswersLL4048-6","title":"LOINC Answer Codes for LL4048-6","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL4048-6"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1223
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:32:34 GMT
last-modified:Fri, 30 Jan 2026 18:32:34 GMT
pragma:no-cache
server:nginx
x-request-id:253-23572691

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26811-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Computational analysis"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26811-2","display" : "Computational analysis"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL4048-6 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL4048-6)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA26811-2 (\"Computational analysis\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA26811-2\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL4048-6) at CodeableConcept.coding[0]\r\n2000 2000: 2000ms : Filter \"LIST=LL4048-6\": Code \"LA26811-2\" found in http://loinc.org|2.81\r\n"}]}

#453

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26811-2","display":"Computational analysis"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL4050-2","name":"LOINCAnswersLL4050-2","title":"LOINC Answer Codes for LL4050-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL4050-2"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2244
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:32:36 GMT
last-modified:Fri, 30 Jan 2026 18:32:36 GMT
pragma:no-cache
server:nginx
x-request-id:253-23572732

{"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://loinc.org/vs/LL4050-2'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26811-2","display" : "Computational analysis"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA26811-2 ('Computational analysis')' was not found in the value set 'http://loinc.org/vs/LL4050-2'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://loinc.org/vs/LL4050-2'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL4050-2 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL4050-2)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA26811-2 (\"Computational analysis\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA26811-2\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL4050-2) at CodeableConcept.coding[0]\r\n2016 2016: 2016ms : Filter \"LIST=LL4050-2\": Code \"LA26811-2\" not found in http://loinc.org|2.81\r\n"}]}

#454

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://hl7.org/fhir/sid/icd-10-cm","code":"C16.0"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:989
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:32:36 GMT
last-modified:Fri, 30 Jan 2026 18:32:36 GMT
pragma:no-cache
server:nginx
x-request-id:253-23572769

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://hl7.org/fhir/sid/icd-10-cm"},{"name" : "code","valueCode" : "C16.0"},{"name" : "version","valueString" : "2024"},{"name" : "display","valueString" : "Malignant neoplasm of cardia"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://hl7.org/fhir/sid/icd-10-cm","code" : "C16.0"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://hl7.org/fhir/sid/icd-10-cm#C16.0 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://hl7.org/fhir/sid/icd-10-cm#C16.0\"\r\n0 0     : 0ms  : Using CodeSystem \"http://hl7.org/fhir/sid/icd-10-cm|2024 (from fhir.tx.support.r4#0.32.0)\" (content = complete)\r\n"}]}

#455

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48002-0","display":"Genomic source class"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:933
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:32:38 GMT
last-modified:Fri, 30 Jan 2026 18:32:38 GMT
pragma:no-cache
server:nginx
x-request-id:253-23572772

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48002-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic source class [Type]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48002-0","display" : "Genomic source class"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48002-0 (\"Genomic source class\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48002-0\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#456

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6684-0","display":"Somatic"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:891
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:32:39 GMT
last-modified:Fri, 30 Jan 2026 18:32:39 GMT
pragma:no-cache
server:nginx
x-request-id:253-23572796

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6684-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Somatic"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6684-0","display" : "Somatic"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA6684-0 (\"Somatic\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA6684-0\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#457

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:8975","display":"PIK3CA"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:32:40 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:c8d1abdd-be43-4226-b912-75e0e5819054
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:c8d1abdd-be43-4226-b912-75e0e5819054
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:8975"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#458

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_006218.4:c.3140A>G","display":"NM_006218.4:c.3140A>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:845
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:32:40 GMT
last-modified:Fri, 30 Jan 2026 18:32:40 GMT
pragma:no-cache
server:nginx
x-request-id:253-23572830

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_006218.4:c.3140A>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_006218.4:c.3140A>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_006218.4:c.3140A>G (\"NM_006218.4:c.3140A>G\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_006218.4:c.3140A>G\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#459

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48019-4","display":"DNA change type"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:911
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:32:41 GMT
last-modified:Fri, 30 Jan 2026 18:32:41 GMT
pragma:no-cache
server:nginx
x-request-id:253-23572834

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48019-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "DNA change type"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48019-4","display" : "DNA change type"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48019-4 (\"DNA change type\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48019-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#460

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:1000002","display":"substitution"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:32:42 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:7fcac972-19b6-41d8-ba84-ad084cc0d0a1
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:7fcac972-19b6-41d8-ba84-ad084cc0d0a1
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:1000002"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#461

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_006209.2:p.His1047Arg","display":"NP_006209.2:p.His1047Arg"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:860
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:32:42 GMT
last-modified:Fri, 30 Jan 2026 18:32:42 GMT
pragma:no-cache
server:nginx
x-request-id:253-23572867

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_006209.2:p.His1047Arg"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_006209.2:p.His1047Arg"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_006209.2:p.His1047Arg (\"NP_006209.2:p.His1047Arg\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_006209.2:p.His1047Arg\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#462

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"51958-7","display":"Transcript reference sequence [ID]"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:968
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:32:43 GMT
last-modified:Fri, 30 Jan 2026 18:32:43 GMT
pragma:no-cache
server:nginx
x-request-id:253-23572869

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51958-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Transcript reference sequence [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "51958-7","display" : "Transcript reference sequence [ID]"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#51958-7 (\"Transcript reference sequence [ID]\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#51958-7\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#463

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_006218.3","display":"NM_006218.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:32:44 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:14079836-c2ff-44a3-bc8a-d3b97c8b2c86
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:14079836-c2ff-44a3-bc8a-d3b97c8b2c86
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NM_006218.3"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#464

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81258-6","display":"Sample VAF"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:924
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:32:45 GMT
last-modified:Fri, 30 Jan 2026 18:32:45 GMT
pragma:no-cache
server:nginx
x-request-id:253-23572904

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81258-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Sample variant allelic frequency [NFr]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81258-6","display" : "Sample VAF"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81258-6 (\"Sample VAF\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81258-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#465

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"82121-5","display":"Allelic read depth"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:920
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:32:47 GMT
last-modified:Fri, 30 Jan 2026 18:32:47 GMT
pragma:no-cache
server:nginx
x-request-id:253-23572931

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82121-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic read depth"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "82121-5","display" : "Allelic read depth"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#82121-5 (\"Allelic read depth\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#82121-5\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#466

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6684-0","display":"Somatic"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL378-1","name":"LOINCAnswersLL378-1","title":"LOINC Answer Codes for LL378-1","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL378-1"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1169
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:32:48 GMT
last-modified:Fri, 30 Jan 2026 18:32:48 GMT
pragma:no-cache
server:nginx
x-request-id:253-23572957

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6684-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Somatic"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6684-0","display" : "Somatic"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL378-1 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL378-1)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA6684-0 (\"Somatic\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA6684-0\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL378-1) at CodeableConcept.coding[0]\r\n1000 1000: 1000ms : Filter \"LIST=LL378-1\": Code \"LA6684-0\" found in http://loinc.org|2.81\r\n"}]}

#467

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:8975","display":"PIK3CA"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:32:48 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:ab2d6216-8a1a-46d7-ae23-e0a5cfff7ac2
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:ab2d6216-8a1a-46d7-ae23-e0a5cfff7ac2
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:8975"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#468

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:8975"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:32:49 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:fbb08a4f-f2b2-497f-a0bb-753a77353d32
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:fbb08a4f-f2b2-497f-a0bb-753a77353d32
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:8975"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}]}

#469

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_006218.4:c.3140A>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1126
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:32:49 GMT
last-modified:Fri, 30 Jan 2026 18:32:49 GMT
pragma:no-cache
server:nginx
x-request-id:253-23572996

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_006218.4:c.3140A>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_006218.4:c.3140A>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_006218.4:c.3140A>G (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_006218.4:c.3140A>G\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n78 78   : 78ms : Code \"NM_006218.4:c.3140A>G\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#470

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:1000002","display":"substitution"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:32:50 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:b452f5ac-b4f2-44d2-9443-ac834adfe337
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:b452f5ac-b4f2-44d2-9443-ac834adfe337
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:1000002"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#471

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:1000002"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0002072"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:32:50 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:e3d702d9-2e24-46a0-bbb1-3185d1814d4e
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x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:e3d702d9-2e24-46a0-bbb1-3185d1814d4e
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:1000002"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}]}

#472

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_006209.2:p.His1047Arg"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1141
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:32:50 GMT
last-modified:Fri, 30 Jan 2026 18:32:50 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573022

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_006209.2:p.His1047Arg"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_006209.2:p.His1047Arg"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_006209.2:p.His1047Arg (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_006209.2:p.His1047Arg\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n63 63   : 63ms : Code \"NP_006209.2:p.His1047Arg\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#473

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:7989","display":"NRAS"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:32:51 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:f341f5b5-508e-4102-905a-87c944d14d9e
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:f341f5b5-508e-4102-905a-87c944d14d9e
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:7989"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#474

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_002524.4:c.34G>T","display":"NM_002524.4:c.34G>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:835
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:32:51 GMT
last-modified:Fri, 30 Jan 2026 18:32:51 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573034

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_002524.4:c.34G>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_002524.4:c.34G>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_002524.4:c.34G>T (\"NM_002524.4:c.34G>T\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_002524.4:c.34G>T\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#475

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_002524.4","display":"NM_002524.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:32:52 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:31b7d8ef-ba4b-47ae-9d65-1506bdae3f7a
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:31b7d8ef-ba4b-47ae-9d65-1506bdae3f7a
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NM_002524.4"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#476

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:7989","display":"NRAS"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:32:52 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:58325aa5-241c-4f98-8d0e-41ca035d6038
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:58325aa5-241c-4f98-8d0e-41ca035d6038
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:7989"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#477

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:7989"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:32:53 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:71d9e4ae-ab96-4636-9860-5287c0f4ee92
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:71d9e4ae-ab96-4636-9860-5287c0f4ee92
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:7989"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}]}

#478

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_002524.4:c.34G>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1116
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:32:53 GMT
last-modified:Fri, 30 Jan 2026 18:32:53 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573067

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_002524.4:c.34G>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_002524.4:c.34G>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_002524.4:c.34G>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_002524.4:c.34G>T\"\r\n15 15   : 15ms : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n15 0    : 15ms : check code in (http://varnomen.hgvs.org) at Coding\r\n78 63   : 78ms : Code \"NM_002524.4:c.34G>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#479

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:16712","display":"FBXW7"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:32:53 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:0dc19008-c65e-47df-902f-cd335eaae5e5
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:0dc19008-c65e-47df-902f-cd335eaae5e5
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:16712"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#480

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_001349798.2:c.1394G>A","display":"NM_001349798.2:c.1394G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:860
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:32:54 GMT
last-modified:Fri, 30 Jan 2026 18:32:54 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573075

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_001349798.2:c.1394G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_001349798.2:c.1394G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_001349798.2:c.1394G>A (\"NM_001349798.2:c.1394G>A\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_001349798.2:c.1394G>A\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#481

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_001336727.1:p.Arg465His","display":"NP_001336727.1:p.Arg465His"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:870
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:32:54 GMT
last-modified:Fri, 30 Jan 2026 18:32:54 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573080

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_001336727.1:p.Arg465His"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_001336727.1:p.Arg465His"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_001336727.1:p.Arg465His (\"NP_001336727.1:p.Arg465His\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_001336727.1:p.Arg465His\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#482

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_001349798.2","display":"NM_001349798.2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:32:54 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:9cda9b8a-8c9f-41c5-ab8e-d15fab0b01df
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:9cda9b8a-8c9f-41c5-ab8e-d15fab0b01df
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NM_001349798.2"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#483

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:16712","display":"FBXW7"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:32:55 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:c9131ced-b86b-496b-b418-2f9d4b6ca7c4
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:c9131ced-b86b-496b-b418-2f9d4b6ca7c4
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:16712"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#484

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:16712"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:32:55 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:d3ff8aca-cc92-4e57-8938-6103e3cf449b
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:d3ff8aca-cc92-4e57-8938-6103e3cf449b
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:16712"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}]}

#485

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_001349798.2:c.1394G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1141
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:32:56 GMT
last-modified:Fri, 30 Jan 2026 18:32:56 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573107

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_001349798.2:c.1394G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_001349798.2:c.1394G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_001349798.2:c.1394G>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_001349798.2:c.1394G>A\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n78 78   : 78ms : Code \"NM_001349798.2:c.1394G>A\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#486

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_001336727.1:p.Arg465His"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1151
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:32:56 GMT
last-modified:Fri, 30 Jan 2026 18:32:56 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573111

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_001336727.1:p.Arg465His"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_001336727.1:p.Arg465His"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_001336727.1:p.Arg465His (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_001336727.1:p.Arg465His\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n62 62   : 62ms : Code \"NP_001336727.1:p.Arg465His\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#487

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:7133","display":"KMT2D"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:32:56 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:1e2f36ae-0854-4d54-ac72-801dbcab2ae1
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:1e2f36ae-0854-4d54-ac72-801dbcab2ae1
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:7133"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#488

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_003482.3:c.7900_7901delCA","display":"NM_003482.3:c.7900_7901delCA"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:880
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:32:56 GMT
last-modified:Fri, 30 Jan 2026 18:32:56 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573125

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_003482.3:c.7900_7901delCA"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_003482.3:c.7900_7901delCA"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_003482.3:c.7900_7901delCA (\"NM_003482.3:c.7900_7901delCA\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_003482.3:c.7900_7901delCA\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#489

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0000159","display":"deletion"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:32:57 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:5ffb2be5-f562-4aec-a610-b93f2c3421c8
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:5ffb2be5-f562-4aec-a610-b93f2c3421c8
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0000159"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#490

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_003482.3","display":"NM_003482.3"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:32:57 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:e52ed549-52ac-4be7-b82e-daa853b55ae3
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:e52ed549-52ac-4be7-b82e-daa853b55ae3
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NM_003482.3"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#491

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:7133","display":"KMT2D"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:32:58 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:1b867f7e-723b-4103-8336-91f8c41e9012
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:1b867f7e-723b-4103-8336-91f8c41e9012
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:7133"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#492

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:7133"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:32:58 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:441c76af-108b-41f0-b135-e0f31acf4e21
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:441c76af-108b-41f0-b135-e0f31acf4e21
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:7133"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}]}

#493

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_003482.3:c.7900_7901delCA"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1161
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:32:59 GMT
last-modified:Fri, 30 Jan 2026 18:32:59 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573159

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_003482.3:c.7900_7901delCA"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_003482.3:c.7900_7901delCA"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_003482.3:c.7900_7901delCA (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_003482.3:c.7900_7901delCA\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n78 78   : 78ms : Code \"NM_003482.3:c.7900_7901delCA\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#494

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0000159","display":"deletion"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:32:59 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:4358d6d4-5455-417e-bef6-64d53f8108bc
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:4358d6d4-5455-417e-bef6-64d53f8108bc
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0000159"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#495

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0000159"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0002072"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:33:00 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:cfac0246-440e-4db4-a4eb-bc5b0b4d9edc
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:cfac0246-440e-4db4-a4eb-bc5b0b4d9edc
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0000159"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}]}

#496

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_006218.3:c.333G>T","display":"NM_006218.3:c.333G>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:840
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:00 GMT
last-modified:Fri, 30 Jan 2026 18:33:00 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573176

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_006218.3:c.333G>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_006218.3:c.333G>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_006218.3:c.333G>T (\"NM_006218.3:c.333G>T\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_006218.3:c.333G>T\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#497

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_006218.3","display":"NM_006218.3"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:33:00 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:97f50104-ad14-4496-88cb-48207548379c
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:97f50104-ad14-4496-88cb-48207548379c
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NM_006218.3"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#498

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_006218.3:c.333G>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1121
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:01 GMT
last-modified:Fri, 30 Jan 2026 18:33:01 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573191

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_006218.3:c.333G>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_006218.3:c.333G>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_006218.3:c.333G>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_006218.3:c.333G>T\"\r\n16 16   : 16ms : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n16 0    : 16ms : check code in (http://varnomen.hgvs.org) at Coding\r\n78 62   : 78ms : Code \"NM_006218.3:c.333G>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#499

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:6126","display":"IRS2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:33:01 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:03c4fc7c-cb5b-4ce6-9a32-9adc53c2e737
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:03c4fc7c-cb5b-4ce6-9a32-9adc53c2e737
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:6126"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#500

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_003749.2:c.3960C>T","display":"NM_003749.2:c.3960C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:845
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:01 GMT
last-modified:Fri, 30 Jan 2026 18:33:01 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573202

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_003749.2:c.3960C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_003749.2:c.3960C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_003749.2:c.3960C>T (\"NM_003749.2:c.3960C>T\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_003749.2:c.3960C>T\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#501

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_003749.2","display":"NM_003749.2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:33:02 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:05c24e3b-2c1b-4576-9c6b-3a9c797de170
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:05c24e3b-2c1b-4576-9c6b-3a9c797de170
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NM_003749.2"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#502

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:6126","display":"IRS2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:33:02 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:e561a686-f89c-431d-80e3-fcf129ca907a
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x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:e561a686-f89c-431d-80e3-fcf129ca907a
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:6126"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#503

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:6126"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:33:03 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:847ad11f-54c5-487a-b62e-06362bf32f1b
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:847ad11f-54c5-487a-b62e-06362bf32f1b
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:6126"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}]}

#504

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_003749.2:c.3960C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1126
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:03 GMT
last-modified:Fri, 30 Jan 2026 18:33:03 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573241

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_003749.2:c.3960C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_003749.2:c.3960C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_003749.2:c.3960C>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_003749.2:c.3960C>T\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n78 78   : 78ms : Code \"NM_003749.2:c.3960C>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#505

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:1787","display":"CDKN2A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:33:04 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:8c2b1a3d-b39a-42be-b687-69686c236ad9
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:8c2b1a3d-b39a-42be-b687-69686c236ad9
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:1787"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#506

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000077.4:c.9_32del"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:824
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:04 GMT
last-modified:Fri, 30 Jan 2026 18:33:04 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573256

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000077.4:c.9_32del"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000077.4:c.9_32del"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_000077.4:c.9_32del (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_000077.4:c.9_32del\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#507

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_000068.1:p.Ala4_Pro11del"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:848
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:04 GMT
last-modified:Fri, 30 Jan 2026 18:33:04 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573257

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_000068.1:p.Ala4_Pro11del"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_000068.1:p.Ala4_Pro11del"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_000068.1:p.Ala4_Pro11del (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_000068.1:p.Ala4_Pro11del\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#508

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_000077.4","display":"NM_000077.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:33:04 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:53d98c7e-d488-4840-a764-25102bb83108
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:53d98c7e-d488-4840-a764-25102bb83108
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NM_000077.4"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#509

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:1787","display":"CDKN2A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:33:05 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:3cef0484-e674-4ca5-b415-c4a069e21858
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:3cef0484-e674-4ca5-b415-c4a069e21858
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:1787"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#510

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:1787"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:33:06 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:81d722bf-ed28-4776-a8fe-ade1b87c8410
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:81d722bf-ed28-4776-a8fe-ade1b87c8410
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:1787"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}]}

#511

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000077.4:c.9_32del"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1126
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:06 GMT
last-modified:Fri, 30 Jan 2026 18:33:06 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573288

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000077.4:c.9_32del"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000077.4:c.9_32del"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_000077.4:c.9_32del (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_000077.4:c.9_32del\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n78 78   : 78ms : Code \"NM_000077.4:c.9_32del\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#512

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_000068.1:p.Ala4_Pro11del"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1156
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:06 GMT
last-modified:Fri, 30 Jan 2026 18:33:06 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573289

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_000068.1:p.Ala4_Pro11del"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_000068.1:p.Ala4_Pro11del"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_000068.1:p.Ala4_Pro11del (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_000068.1:p.Ala4_Pro11del\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n78 78   : 78ms : Code \"NP_000068.1:p.Ala4_Pro11del\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#513

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:9949","display":"RECQL4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:33:06 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:fd5ba546-e8b3-4f8b-80da-d04ad232b50e
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:fd5ba546-e8b3-4f8b-80da-d04ad232b50e
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:9949"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#514

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_004260.4:c.2086C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:824
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:07 GMT
last-modified:Fri, 30 Jan 2026 18:33:07 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573304

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_004260.4:c.2086C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_004260.4:c.2086C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_004260.4:c.2086C>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_004260.4:c.2086C>T\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#515

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_004251.4:p.Arg696Cys"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:832
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:07 GMT
last-modified:Fri, 30 Jan 2026 18:33:07 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573306

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_004251.4:p.Arg696Cys"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_004251.4:p.Arg696Cys"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_004251.4:p.Arg696Cys (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_004251.4:p.Arg696Cys\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#516

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_004260.4","display":"NM_004260.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:33:07 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:8e38750f-3155-4098-b36a-831364d419bd
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:8e38750f-3155-4098-b36a-831364d419bd
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NM_004260.4"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#517

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:9949","display":"RECQL4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:33:08 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:93869c4f-33bd-4c41-a61f-448112b88ba9
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:93869c4f-33bd-4c41-a61f-448112b88ba9
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:9949"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#518

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:9949"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:33:08 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:64b90991-3249-41ce-8673-1bdf0c6f7afd
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:64b90991-3249-41ce-8673-1bdf0c6f7afd
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:9949"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}]}

#519

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_004260.4:c.2086C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1126
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:09 GMT
last-modified:Fri, 30 Jan 2026 18:33:09 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573336

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_004260.4:c.2086C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_004260.4:c.2086C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_004260.4:c.2086C>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_004260.4:c.2086C>T\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n62 62   : 62ms : Code \"NM_004260.4:c.2086C>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#520

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_004251.4:p.Arg696Cys"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1136
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:09 GMT
last-modified:Fri, 30 Jan 2026 18:33:09 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573338

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_004251.4:p.Arg696Cys"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_004251.4:p.Arg696Cys"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_004251.4:p.Arg696Cys (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_004251.4:p.Arg696Cys\"\r\n16 16   : 16ms : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n16 0    : 16ms : check code in (http://varnomen.hgvs.org) at Coding\r\n94 78   : 94ms : Code \"NP_004251.4:p.Arg696Cys\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#521

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:10483","display":"RYR1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:33:09 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:4420c361-935e-40f1-b8c0-f0a1c4c30425
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:4420c361-935e-40f1-b8c0-f0a1c4c30425
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:10483"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#522

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000540.3:c.4964G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:824
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:10 GMT
last-modified:Fri, 30 Jan 2026 18:33:10 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573349

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000540.3:c.4964G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000540.3:c.4964G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_000540.3:c.4964G>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_000540.3:c.4964G>A\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#523

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_000531.2:p.Arg1655Leu"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:836
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:10 GMT
last-modified:Fri, 30 Jan 2026 18:33:10 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573351

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_000531.2:p.Arg1655Leu"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_000531.2:p.Arg1655Leu"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_000531.2:p.Arg1655Leu (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_000531.2:p.Arg1655Leu\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#524

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_000540.2","display":"NM_000540.3"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:33:10 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:56a1ebf9-c292-4e4f-88dc-d0cc23ab8abb
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:56a1ebf9-c292-4e4f-88dc-d0cc23ab8abb
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NM_000540.2"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#525

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:10483","display":"RYR1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:33:11 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:e4f620f8-293c-4384-9e76-f0d6859ea1e9
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:e4f620f8-293c-4384-9e76-f0d6859ea1e9
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:10483"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#526

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:10483"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:33:11 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:578282b7-ed58-4f1b-a9db-2ce14bcac16b
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:578282b7-ed58-4f1b-a9db-2ce14bcac16b
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:10483"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}]}

#527

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000540.3:c.4964G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1126
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:12 GMT
last-modified:Fri, 30 Jan 2026 18:33:12 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573380

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000540.3:c.4964G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000540.3:c.4964G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_000540.3:c.4964G>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_000540.3:c.4964G>A\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n78 78   : 78ms : Code \"NM_000540.3:c.4964G>A\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#528

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_000531.2:p.Arg1655Leu"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1141
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:12 GMT
last-modified:Fri, 30 Jan 2026 18:33:12 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573384

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_000531.2:p.Arg1655Leu"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_000531.2:p.Arg1655Leu"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_000531.2:p.Arg1655Leu (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_000531.2:p.Arg1655Leu\"\r\n16 16   : 16ms : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n16 0    : 16ms : check code in (http://varnomen.hgvs.org) at Coding\r\n78 62   : 78ms : Code \"NP_000531.2:p.Arg1655Leu\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#529

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:10519","display":"SACS"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:33:12 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:d109f9e3-ec1f-4502-94be-b772c96757cd
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:d109f9e3-ec1f-4502-94be-b772c96757cd
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:10519"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#530

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_014363.5:c.12118G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:828
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:13 GMT
last-modified:Fri, 30 Jan 2026 18:33:13 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573395

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_014363.5:c.12118G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_014363.5:c.12118G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_014363.5:c.12118G>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_014363.5:c.12118G>A\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#531

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_014363.5","display":"NM_014363.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:33:13 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:e38740db-c58d-4d32-989f-02ecc20729e3
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:e38740db-c58d-4d32-989f-02ecc20729e3
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NM_014363.5"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#532

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:10519","display":"SACS"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:33:13 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:81029b93-35ed-475b-a89d-d4c14654711d
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:81029b93-35ed-475b-a89d-d4c14654711d
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:10519"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#533

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:10519"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:33:14 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:13933523-296b-405e-b920-8f2998481ab0
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:13933523-296b-405e-b920-8f2998481ab0
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:10519"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}]}

#534

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_014363.5:c.12118G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1131
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:14 GMT
last-modified:Fri, 30 Jan 2026 18:33:14 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573422

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_014363.5:c.12118G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_014363.5:c.12118G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_014363.5:c.12118G>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_014363.5:c.12118G>A\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n79 79   : 79ms : Code \"NM_014363.5:c.12118G>A\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#535

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:11086","display":"SLIT2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:33:15 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:6c4f46b6-b275-43c7-a795-8e1aa38570c8
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:6c4f46b6-b275-43c7-a795-8e1aa38570c8
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:11086"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#536

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_004787.3:c.1290C>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:824
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:15 GMT
last-modified:Fri, 30 Jan 2026 18:33:15 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573434

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_004787.3:c.1290C>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_004787.3:c.1290C>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_004787.3:c.1290C>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_004787.3:c.1290C>A\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#537

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_004787.3","display":"NM_004787.3"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:33:15 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:0ff27113-bbdc-4d98-be57-e993a6465589
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:0ff27113-bbdc-4d98-be57-e993a6465589
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NM_004787.3"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#538

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:11086","display":"SLIT2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:33:16 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:705870af-5161-46f6-83da-1a332ed6f003
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:705870af-5161-46f6-83da-1a332ed6f003
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:11086"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#539

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:11086"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:33:17 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:9a339d1a-5d39-4f1d-82f7-8122689c6bb4
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x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:9a339d1a-5d39-4f1d-82f7-8122689c6bb4
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:11086"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}]}

#540

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_004787.3:c.1290C>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1126
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:17 GMT
last-modified:Fri, 30 Jan 2026 18:33:17 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573480

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_004787.3:c.1290C>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_004787.3:c.1290C>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_004787.3:c.1290C>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_004787.3:c.1290C>A\"\r\n15 15   : 15ms : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n15 0    : 15ms : check code in (http://varnomen.hgvs.org) at Coding\r\n78 63   : 78ms : Code \"NM_004787.3:c.1290C>A\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#541

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:11100","display":"SMARCA4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:33:17 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:54b8ee5d-9d2e-4735-8f10-87eba786eb4f
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:54b8ee5d-9d2e-4735-8f10-87eba786eb4f
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:11100"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#542

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_003072.5:c.2372C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:824
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:17 GMT
last-modified:Fri, 30 Jan 2026 18:33:17 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573496

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_003072.5:c.2372C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_003072.5:c.2372C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_003072.5:c.2372C>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_003072.5:c.2372C>T\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#543

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_003063.2:p.Ala791Val"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:832
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:18 GMT
last-modified:Fri, 30 Jan 2026 18:33:18 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573501

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_003063.2:p.Ala791Val"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_003063.2:p.Ala791Val"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_003063.2:p.Ala791Val (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_003063.2:p.Ala791Val\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#544

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_003072.5","display":"NM_003072.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:33:18 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:a6965267-7922-4e2f-b0af-a47c100aeb96
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:a6965267-7922-4e2f-b0af-a47c100aeb96
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NM_003072.5"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#545

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:11100","display":"SMARCA4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:33:19 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:64f38012-ad62-4771-8687-d09aa5979b0c
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:64f38012-ad62-4771-8687-d09aa5979b0c
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:11100"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#546

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:11100"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:33:19 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:ca6459c8-20d7-4256-9fa5-5bd17a5395c3
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:ca6459c8-20d7-4256-9fa5-5bd17a5395c3
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:11100"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}]}

#547

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_003072.5:c.2372C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1126
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:19 GMT
last-modified:Fri, 30 Jan 2026 18:33:19 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573547

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_003072.5:c.2372C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_003072.5:c.2372C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_003072.5:c.2372C>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_003072.5:c.2372C>T\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n78 78   : 78ms : Code \"NM_003072.5:c.2372C>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#548

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_003063.2:p.Ala791Val"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1136
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:20 GMT
last-modified:Fri, 30 Jan 2026 18:33:20 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573553

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_003063.2:p.Ala791Val"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_003063.2:p.Ala791Val"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_003063.2:p.Ala791Val (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_003063.2:p.Ala791Val\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n79 79   : 79ms : Code \"NP_003063.2:p.Ala791Val\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#549

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81695-9","display":"Microsatellite instability [Interpretation] in Cancer specimen Qualitative"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1088
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:22 GMT
last-modified:Fri, 30 Jan 2026 18:33:22 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573575

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81695-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Microsatellite instability [Interpretation] in Cancer specimen Qualitative"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81695-9","display" : "Microsatellite instability [Interpretation] in Cancer specimen Qualitative"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81695-9 (\"Microsatellite instability [Interpretation] in Cancer specimen Qualitative\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81695-9\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#550

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA14122-8","display":"Stable"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:892
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:24 GMT
last-modified:Fri, 30 Jan 2026 18:33:24 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573600

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA14122-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Stable"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA14122-8","display" : "Stable"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA14122-8 (\"Stable\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA14122-8\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#551

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000009.12:g.5073770G>T","display":"NC_000009.12:g.5073770G>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:865
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:24 GMT
last-modified:Fri, 30 Jan 2026 18:33:24 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573631

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000009.12:g.5073770G>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000009.12:g.5073770G>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000009.12:g.5073770G>T (\"NC_000009.12:g.5073770G>T\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000009.12:g.5073770G>T\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#552

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_004963.1:p.Val617Phe","display":"NP_004963.1:p.Val617Phe"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:855
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:24 GMT
last-modified:Fri, 30 Jan 2026 18:33:24 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573632

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_004963.1:p.Val617Phe"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_004963.1:p.Val617Phe"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_004963.1:p.Val617Phe (\"NP_004963.1:p.Val617Phe\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_004963.1:p.Val617Phe\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#553

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"JAK2","display":"JAK2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:33:24 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:7ad7343b-ee89-40d7-8b49-de1b124dbd18
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:7ad7343b-ee89-40d7-8b49-de1b124dbd18
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"JAK2"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#554

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000009.12:g.5073770G>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1146
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:25 GMT
last-modified:Fri, 30 Jan 2026 18:33:25 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573649

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000009.12:g.5073770G>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000009.12:g.5073770G>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000009.12:g.5073770G>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000009.12:g.5073770G>T\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n62 62   : 62ms : Code \"NC_000009.12:g.5073770G>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#555

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_004963.1:p.Val617Phe"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1136
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:25 GMT
last-modified:Fri, 30 Jan 2026 18:33:25 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573652

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_004963.1:p.Val617Phe"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_004963.1:p.Val617Phe"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_004963.1:p.Val617Phe (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_004963.1:p.Val617Phe\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n62 62   : 62ms : Code \"NP_004963.1:p.Val617Phe\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#556

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"JAK2","display":"JAK2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:33:25 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:1b8b460c-c57e-4480-b8d7-72fcf391b0ca
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:1b8b460c-c57e-4480-b8d7-72fcf391b0ca
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"JAK2"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#557

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"JAK2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:33:26 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:2b2a44a5-5f53-467e-8ba6-e8a8c7640616
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:2b2a44a5-5f53-467e-8ba6-e8a8c7640616
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"JAK2"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}]}

#558

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000004.11:g.55972974T>A","display":"NC_000004.11:g.55972974T>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:870
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:26 GMT
last-modified:Fri, 30 Jan 2026 18:33:26 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573673

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000004.11:g.55972974T>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000004.11:g.55972974T>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000004.11:g.55972974T>A (\"NC_000004.11:g.55972974T>A\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000004.11:g.55972974T>A\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#559

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_002244.1:p.Gln472His","display":"NP_002244.1:p.Gln472His"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:855
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:26 GMT
last-modified:Fri, 30 Jan 2026 18:33:26 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573680

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_002244.1:p.Gln472His"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_002244.1:p.Gln472His"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_002244.1:p.Gln472His (\"NP_002244.1:p.Gln472His\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_002244.1:p.Gln472His\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#560

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"KDR","display":"KDR"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:33:27 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:1ace5c2f-cd46-467a-9c14-5da9f4fcca27
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:1ace5c2f-cd46-467a-9c14-5da9f4fcca27
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"KDR"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#561

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000004.11:g.55972974T>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1151
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:27 GMT
last-modified:Fri, 30 Jan 2026 18:33:27 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573693

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000004.11:g.55972974T>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000004.11:g.55972974T>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000004.11:g.55972974T>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000004.11:g.55972974T>A\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n78 78   : 78ms : Code \"NC_000004.11:g.55972974T>A\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#562

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_002244.1:p.Gln472His"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1136
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:27 GMT
last-modified:Fri, 30 Jan 2026 18:33:27 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573696

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_002244.1:p.Gln472His"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_002244.1:p.Gln472His"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_002244.1:p.Gln472His (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_002244.1:p.Gln472His\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n78 78   : 78ms : Code \"NP_002244.1:p.Gln472His\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#563

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"KDR","display":"KDR"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:33:28 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:e5279347-24ea-45e6-b71a-b84467ae6434
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:e5279347-24ea-45e6-b71a-b84467ae6434
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"KDR"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#564

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"KDR"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:33:28 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:774e48f2-8632-4b13-b7b6-83ea333b704d
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:774e48f2-8632-4b13-b7b6-83ea333b704d
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"KDR"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}]}

#565

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000002.12:g.211713666_211713668del","display":"NC_000002.12:g.211713666_211713668del"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:925
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:28 GMT
last-modified:Fri, 30 Jan 2026 18:33:28 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573718

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000002.12:g.211713666_211713668del"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000002.12:g.211713666_211713668del"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000002.12:g.211713666_211713668del (\"NC_000002.12:g.211713666_211713668del\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000002.12:g.211713666_211713668del\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#566

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"ERBB4","display":"ERBB4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:33:29 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:e14eec7e-b137-4de9-b10c-ed114e44659c
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:e14eec7e-b137-4de9-b10c-ed114e44659c
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"ERBB4"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#567

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000002.12:g.211713666_211713668del"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1206
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:29 GMT
last-modified:Fri, 30 Jan 2026 18:33:29 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573728

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000002.12:g.211713666_211713668del"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000002.12:g.211713666_211713668del"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000002.12:g.211713666_211713668del (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000002.12:g.211713666_211713668del\"\r\n16 16   : 16ms : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n16 0    : 16ms : check code in (http://varnomen.hgvs.org) at Coding\r\n78 62   : 78ms : Code \"NC_000002.12:g.211713666_211713668del\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#568

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"ERBB4","display":"ERBB4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:33:29 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:4f13b7ce-875d-441e-85fa-70af97eec784
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:4f13b7ce-875d-441e-85fa-70af97eec784
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"ERBB4"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#569

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"ERBB4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:33:30 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:ad306a3a-f5cf-4927-b59e-784d44e68d3e
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x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:ad306a3a-f5cf-4927-b59e-784d44e68d3e
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"ERBB4"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}]}

#570

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://www.nlm.nih.gov/research/umls/rxnorm","code":"1193326","display":"Ruxolitinib"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1030
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:30 GMT
last-modified:Fri, 30 Jan 2026 18:33:30 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573746

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://www.nlm.nih.gov/research/umls/rxnorm"},{"name" : "code","valueCode" : "1193326"},{"name" : "version","valueString" : "??"},{"name" : "display","valueString" : "ruxolitinib"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://www.nlm.nih.gov/research/umls/rxnorm","code" : "1193326","display" : "Ruxolitinib"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.nlm.nih.gov/research/umls/rxnorm#1193326 (\"Ruxolitinib\")]\"\r\n0 0     : 0ms  : Check \"http://www.nlm.nih.gov/research/umls/rxnorm#1193326\"\r\n0 0     : 0ms  : Using CodeSystem \"http://www.nlm.nih.gov/research/umls/rxnorm|??\" (content = complete)\r\n"}]}

#571

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6677-4","display":"Responsive"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-length:900
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:32 GMT
last-modified:Fri, 30 Jan 2026 18:33:32 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573748

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6677-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Responsive"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6677-4","display" : "Responsive"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA6677-4 (\"Responsive\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA6677-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#572

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6677-4","display":"Responsive"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"genetic-therapeutic-implications-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs","version":"4.0.0-cibuild","name":"GeneticTherapeuticImplicationsVS","title":"Genetic Therapeutic Implications","status":"active","experimental":false,"date":"2026-01-30T18:21:39+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for terms that describe a predicted ramification based on the presence of associated molecular finding(s).","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This material contains content from LOINC (http://loinc.org). LOINC is copyright © 1995-2020, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC® is a registered United States trademark of Regenstrief Institute, Inc.\nThis value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement.","compose":{"include":[{"system":"http://loinc.org","concept":[{"code":"LA10315-2","display":"Ultrarapid metabolizer"},{"code":"LA25391-6","display":"Normal metabolizer"},{"code":"LA25390-8","display":"Rapid metabolizer"},{"code":"LA10317-8","display":"Intermediate metabolizer"},{"code":"LA9657-3","display":"Poor metabolizer"},{"code":"LA19542-2","display":"Low Risk"},{"code":"LA19541-4","display":"High Risk"},{"code":"LA6676-6","display":"Resistant"},{"code":"LA6677-4","display":"Responsive"},{"code":"LA9660-7","display":"Presumed resistant"},{"code":"LA9661-5","display":"Presumed responsive"},{"code":"LA6682-4","display":"Unknown Significance"},{"code":"LA6675-8","display":"Benign"},{"code":"LA6674-1","display":"Presumed Benign"},{"code":"LA9662-3","display":"Presumed non-responsive"},{"code":"LA25392-4","display":"Increased function"},{"code":"LA25393-2","display":"Normal function"},{"code":"LA25395-7","display":"Decreased function"},{"code":"LA25394-0","display":"Poor function"}]},{"system":"http://snomed.info/sct","concept":[{"code":"444734003","display":"Does not meet eligibility criteria for clinical trial (finding)"},{"code":"399223003","display":"Patient eligible for clinical trial (finding)"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
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connection:keep-alive
content-length:1770
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:32 GMT
last-modified:Fri, 30 Jan 2026 18:33:32 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573773

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6677-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Responsive"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6677-4","display" : "Responsive"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n31 31   : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-cibuild for validation purposes\r\n31 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n31 0    : 0ms  : Prepare include: \"(http://loinc.org)(LA10315-2,LA25391-6,LA25390-8,LA10317-8,LA9657-3,LA19542-2,LA19541-4,LA6676-6,LA6677-4,LA9660-7,LA9661-5,LA6682-4,LA6675-8,LA6674-1,LA9662-3,LA25392-4,LA25393-2,LA25395-7,LA25394-0)\"\r\n31 0    : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n31 0    : 0ms  : Prepare include: \"(http://snomed.info/sct)(444734003,399223003)\"\r\n31 0    : 0ms  : CodeSystem found: \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\"\r\n31 0    : 0ms  : Validate \"[http://loinc.org#LA6677-4 (\"Responsive\")]\"\r\n31 0    : 0ms  : Check \"http://loinc.org#LA6677-4\"\r\n31 0    : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n31 0    : 0ms  : check code in (http://loinc.org)(LA10315-2,LA25391-6,LA25390-8,LA10317-8,LA9657-3,LA19542-2,LA19541-4,LA6676-6,LA6677-4,LA9660-7,LA9661-5,LA6682-4,LA6675-8,LA6674-1,LA9662-3,LA25392-4,LA25393-2,LA25395-7,LA25394-0) at CodeableConcept.coding[0]\r\n31 0    : 0ms  : Code \"LA6677-4\" found in http://loinc.org|2.81\r\n"}]}

#573

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"51963-7","display":"Medication assessed"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:928
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:33 GMT
last-modified:Fri, 30 Jan 2026 18:33:33 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573777

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51963-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Medication assessed [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "51963-7","display" : "Medication assessed"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#51963-7 (\"Medication assessed\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#51963-7\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#574

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA14122-8","display":"Stable"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL1971-2","name":"LOINCAnswersLL1971-2","title":"LOINC Answer Codes for LL1971-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL1971-2"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-length:2196
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:36 GMT
last-modified:Fri, 30 Jan 2026 18:33:36 GMT
pragma:no-cache
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x-request-id:253-23573808

{"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1971-2'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA14122-8","display" : "Stable"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA14122-8 ('Stable')' was not found in the value set 'http://loinc.org/vs/LL1971-2'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1971-2'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15   : 0ms  : Analysing http://loinc.org/vs/LL1971-2 for validation purposes\r\n15 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n15 0    : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL1971-2)\"\r\n15 0    : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n15 0    : 0ms  : Validate \"[http://loinc.org#LA14122-8 (\"Stable\")]\"\r\n15 0    : 0ms  : Check \"http://loinc.org#LA14122-8\"\r\n15 0    : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n15 0    : 0ms  : check code in (http://loinc.org)(LIST=LL1971-2) at CodeableConcept.coding[0]\r\n2031 2016: 2016ms : Filter \"LIST=LL1971-2\": Code \"LA14122-8\" not found in http://loinc.org|2.81\r\n"}]}

#575

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA14122-8","display":"Stable"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"sequence-phase-relationship-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs","version":"4.0.0-cibuild","name":"SequencePhaseRelationshipVS","title":"Sequence Phase Relationships","status":"active","experimental":false,"date":"2026-01-30T18:21:39+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for specific types of relationships","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"compose":{"include":[{"system":"http://terminology.hl7.org/CodeSystem/sequence-phase-relationship-cs"}]}}},{"name":"tx-resource","resource":{"resourceType":"CodeSystem","id":"sequence-phase-relationship-cs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://terminology.hl7.org/CodeSystem/sequence-phase-relationship-cs","version":"4.0.0-cibuild","name":"SequencePhaseRelationshipCS","title":"Sequence Phase Relationship Codes","status":"active","experimental":false,"date":"2026-01-30T18:21:39+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Code System for specific types of relationships","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"caseSensitive":true,"content":"complete","count":4,"concept":[{"code":"Cis","display":"Cis","definition":"Phase is in cis (same chromosome)"},{"code":"Trans","display":"Trans","definition":"Phase is in trans (different chromosomes)"},{"code":"Indeterminate","display":"Indeterminate","definition":"Phase is unable to be determined"},{"code":"Unknown","display":"Unknown","definition":"Phase is unknown"}]}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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date:Fri, 30 Jan 2026 18:33:36 GMT
last-modified:Fri, 30 Jan 2026 18:33:36 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573837

{"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-cibuild'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA14122-8","display" : "Stable"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA14122-8 ('Stable')' was not found in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-cibuild'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-cibuild'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n31 31   : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-cibuild for validation purposes\r\n31 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n31 0    : 0ms  : Prepare include: \"(http://terminology.hl7.org/CodeSystem/sequence-phase-relationship-cs)\"\r\n31 0    : 0ms  : CodeSystem found: \"http://terminology.hl7.org/CodeSystem/sequence-phase-relationship-cs|4.0.0-cibuild\"\r\n31 0    : 0ms  : Validate \"[http://loinc.org#LA14122-8 (\"Stable\")]\"\r\n31 0    : 0ms  : Check \"http://loinc.org#LA14122-8\"\r\n"}]}

#576

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26423-6","display":"Increase dose"}],"text":"Any Increase does Recommendation Text from the provider"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL4049-4","name":"LOINCAnswersLL4049-4","title":"LOINC Answer Codes for LL4049-4","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL4049-4"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1263
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:40 GMT
last-modified:Fri, 30 Jan 2026 18:33:40 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573857

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26423-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Increase dose"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26423-6","display" : "Increase dose"}],"text" : "Any Increase does Recommendation Text from the provider"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL4049-4 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL4049-4)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA26423-6 (\"Increase dose\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA26423-6\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL4049-4) at CodeableConcept.coding[0]\r\n2015 2015: 2015ms : Filter \"LIST=LL4049-4\": Code \"LA26423-6\" found in http://loinc.org|2.81\r\n"}]}

#577

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://www.nlm.nih.gov/research/umls/rxnorm","code":"103","display":"mercaptopurine"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1023
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:40 GMT
last-modified:Fri, 30 Jan 2026 18:33:40 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573890

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://www.nlm.nih.gov/research/umls/rxnorm"},{"name" : "code","valueCode" : "103"},{"name" : "version","valueString" : "??"},{"name" : "display","valueString" : "mercaptopurine"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://www.nlm.nih.gov/research/umls/rxnorm","code" : "103","display" : "mercaptopurine"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.nlm.nih.gov/research/umls/rxnorm#103 (\"mercaptopurine\")]\"\r\n0 0     : 0ms  : Check \"http://www.nlm.nih.gov/research/umls/rxnorm#103\"\r\n0 0     : 0ms  : Using CodeSystem \"http://www.nlm.nih.gov/research/umls/rxnorm|??\" (content = complete)\r\n"}]}

#578

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"84413-4","display":"genotype display name"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:929
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:41 GMT
last-modified:Fri, 30 Jan 2026 18:33:41 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573893

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "84413-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genotype display name"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "84413-4","display" : "genotype display name"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#84413-4 (\"genotype display name\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#84413-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#579

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"CYP2C9","display":"CYP2C9 *4/*35B"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:33:42 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:2b17c02a-4c5a-4c19-a17a-e639c819a37d
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:2b17c02a-4c5a-4c19-a17a-e639c819a37d
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"CYP2C9"},{"name":"system","valueUri":"http://www.pharmvar.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.pharmvar.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.pharmvar.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.pharmvar.org was not found"}]}

#580

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"CYP2C9","display":"CYP2C9 *4/*35B"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:33:42 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:e79c666c-b9a5-4dad-8862-34b3897bf2d1
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:e79c666c-b9a5-4dad-8862-34b3897bf2d1
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"CYP2C9"},{"name":"system","valueUri":"http://www.pharmvar.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.pharmvar.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.pharmvar.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.pharmvar.org was not found"}]}

#581

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"84414-2","display":"Haplotype Name"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:908
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:44 GMT
last-modified:Fri, 30 Jan 2026 18:33:44 GMT
pragma:no-cache
server:nginx
x-request-id:253-23573927

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "84414-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Haplotype name"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "84414-2","display" : "Haplotype Name"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#84414-2 (\"Haplotype Name\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#84414-2\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#582

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"CYP2C9","display":"CYP2C9 *35B"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:33:44 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:c239cb46-056d-44ba-ba79-b33edf03fe07
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:c239cb46-056d-44ba-ba79-b33edf03fe07
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"CYP2C9"},{"name":"system","valueUri":"http://www.pharmvar.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.pharmvar.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.pharmvar.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.pharmvar.org was not found"}]}

#583

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NG-007726.3"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:33:45 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:b24b4f43-d101-424d-bab8-0916b88d43c9
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:b24b4f43-d101-424d-bab8-0916b88d43c9
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NG-007726.3"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#584

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/projects/SNP","code":"rs12345"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:33:45 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:805e00eb-a6f5-4add-ac6c-4f60cd52149e
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:805e00eb-a6f5-4add-ac6c-4f60cd52149e
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"rs12345"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/projects/SNP was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/projects/SNP was not found"}]}

#585

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"CYP2C9","display":"CYP2C9 *4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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date:Fri, 30 Jan 2026 18:33:46 GMT
server:nginx
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"CYP2C9"},{"name":"system","valueUri":"http://www.pharmvar.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.pharmvar.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.pharmvar.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.pharmvar.org was not found"}]}

#586

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NG_007726.3"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:33:47 GMT
server:nginx
vary:Origin
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x-content-type-options:nosniff
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x-request-id:31544294-9572-4efc-84c8-fc216b11cfe4
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NG_007726.3"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#587

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/projects/SNP","code":"rs233455"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
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server:nginx
vary:Origin
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vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
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x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:f474fd29-b483-427d-af6b-97b4c39c5b61
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"rs233455"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/projects/SNP was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/projects/SNP was not found"}]}

#588

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"CYP2C9","display":"CYP2C9 *35B"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:33:48 GMT
server:nginx
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vary:Access-Control-Request-Headers
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x-content-type-options:nosniff
x-correlation-id:fa3b6f43-df08-4501-b86a-b594db0d999c
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"CYP2C9"},{"name":"system","valueUri":"http://www.pharmvar.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.pharmvar.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.pharmvar.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.pharmvar.org was not found"}]}

#589

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"CYP2C9","display":"CYP2C9 *4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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server:nginx
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vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:9ef44ba9-0f10-483a-91c0-690c771dd91e
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x-request-id:9ef44ba9-0f10-483a-91c0-690c771dd91e
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"CYP2C9"},{"name":"system","valueUri":"http://www.pharmvar.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.pharmvar.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.pharmvar.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.pharmvar.org was not found"}]}

#590

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26423-6","display":"Increase dose"}],"text":"Any Increase does Recommendation Text from the provider"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL1037-2","name":"LOINCAnswersLL1037-2","title":"LOINC Answer Codes for LL1037-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL1037-2"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
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date:Fri, 30 Jan 2026 18:33:50 GMT
last-modified:Fri, 30 Jan 2026 18:33:50 GMT
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server:nginx
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{"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1037-2'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26423-6","display" : "Increase dose"}],"text" : "Any Increase does Recommendation Text from the provider"}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA26423-6 ('Increase dose')' was not found in the value set 'http://loinc.org/vs/LL1037-2'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1037-2'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL1037-2 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL1037-2)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA26423-6 (\"Increase dose\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA26423-6\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL1037-2) at CodeableConcept.coding[0]\r\n2016 2016: 2016ms : Filter \"LIST=LL1037-2\": Code \"LA26423-6\" not found in http://loinc.org|2.81\r\n"}]}

#591

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"CYP2C9","display":"CYP2C9 *4/*35B"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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date:Fri, 30 Jan 2026 18:33:51 GMT
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"CYP2C9"},{"name":"system","valueUri":"http://www.pharmvar.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.pharmvar.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.pharmvar.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.pharmvar.org was not found"}]}

#592

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"CYP2C9","display":"CYP2C9 *35B"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"CYP2C9"},{"name":"system","valueUri":"http://www.pharmvar.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.pharmvar.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.pharmvar.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.pharmvar.org was not found"}]}

#593

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"CYP2C9","display":"CYP2C9 *4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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x-request-id:31302ede-384c-4605-a7b8-f62e709ee56b
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"CYP2C9"},{"name":"system","valueUri":"http://www.pharmvar.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.pharmvar.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.pharmvar.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.pharmvar.org was not found"}]}

#594

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26423-6","display":"Increase dose"}],"text":"Any Increase does Recommendation Text from the provider"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:980
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:54 GMT
last-modified:Fri, 30 Jan 2026 18:33:54 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574065

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26423-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Increase dose"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26423-6","display" : "Increase dose"}],"text" : "Any Increase does Recommendation Text from the provider"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA26423-6 (\"Increase dose\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA26423-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#595

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"706687001","display":"Software (physical object)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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cache-control:public, max-age=600
connection:keep-alive
content-length:1072
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:54 GMT
last-modified:Fri, 30 Jan 2026 18:33:54 GMT
pragma:no-cache
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x-request-id:253-23574088

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "706687001"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Software"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "706687001","display" : "Software (physical object)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://snomed.info/sct#706687001 (\"Software (physical object)\")]\"\r\n0 0     : 0ms  : Check \"http://snomed.info/sct#706687001\"\r\n0 0     : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#596

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","code":"14909","display":"HLA-B*15:02"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
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date:Fri, 30 Jan 2026 18:33:55 GMT
server:nginx
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"14909"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/clinvar"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/clinvar was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/clinvar"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/clinvar was not found"}]}

#597

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","code":"14909","display":"HLA-B*15:02"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
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date:Fri, 30 Jan 2026 18:33:55 GMT
server:nginx
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"14909"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/clinvar"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/clinvar was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/clinvar"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/clinvar was not found"}]}

#598

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA19541-4","display":"High risk"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:901
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:57 GMT
last-modified:Fri, 30 Jan 2026 18:33:57 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574105

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA19541-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "High risk"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA19541-4","display" : "High risk"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA19541-4 (\"High risk\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA19541-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#599

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://www.nlm.nih.gov/research/umls/rxnorm","code":"2002","display":"Carbamazepine"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
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content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:57 GMT
last-modified:Fri, 30 Jan 2026 18:33:57 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574127

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://www.nlm.nih.gov/research/umls/rxnorm"},{"name" : "code","valueCode" : "2002"},{"name" : "version","valueString" : "??"},{"name" : "display","valueString" : "carbamazepine"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://www.nlm.nih.gov/research/umls/rxnorm","code" : "2002","display" : "Carbamazepine"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.nlm.nih.gov/research/umls/rxnorm#2002 (\"Carbamazepine\")]\"\r\n0 0     : 0ms  : Check \"http://www.nlm.nih.gov/research/umls/rxnorm#2002\"\r\n0 0     : 0ms  : Using CodeSystem \"http://www.nlm.nih.gov/research/umls/rxnorm|??\" (content = complete)\r\n"}]}

#600

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA19541-4","display":"High risk"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"genetic-therapeutic-implications-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs","version":"4.0.0-cibuild","name":"GeneticTherapeuticImplicationsVS","title":"Genetic Therapeutic Implications","status":"active","experimental":false,"date":"2026-01-30T18:21:39+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for terms that describe a predicted ramification based on the presence of associated molecular finding(s).","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This material contains content from LOINC (http://loinc.org). LOINC is copyright © 1995-2020, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC® is a registered United States trademark of Regenstrief Institute, Inc.\nThis value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement.","compose":{"include":[{"system":"http://loinc.org","concept":[{"code":"LA10315-2","display":"Ultrarapid metabolizer"},{"code":"LA25391-6","display":"Normal metabolizer"},{"code":"LA25390-8","display":"Rapid metabolizer"},{"code":"LA10317-8","display":"Intermediate metabolizer"},{"code":"LA9657-3","display":"Poor metabolizer"},{"code":"LA19542-2","display":"Low Risk"},{"code":"LA19541-4","display":"High Risk"},{"code":"LA6676-6","display":"Resistant"},{"code":"LA6677-4","display":"Responsive"},{"code":"LA9660-7","display":"Presumed resistant"},{"code":"LA9661-5","display":"Presumed responsive"},{"code":"LA6682-4","display":"Unknown Significance"},{"code":"LA6675-8","display":"Benign"},{"code":"LA6674-1","display":"Presumed Benign"},{"code":"LA9662-3","display":"Presumed non-responsive"},{"code":"LA25392-4","display":"Increased function"},{"code":"LA25393-2","display":"Normal function"},{"code":"LA25395-7","display":"Decreased function"},{"code":"LA25394-0","display":"Poor function"}]},{"system":"http://snomed.info/sct","concept":[{"code":"444734003","display":"Does not meet eligibility criteria for clinical trial (finding)"},{"code":"399223003","display":"Patient eligible for clinical trial (finding)"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
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content-length:1772
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date:Fri, 30 Jan 2026 18:33:57 GMT
last-modified:Fri, 30 Jan 2026 18:33:57 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574128

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA19541-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "High risk"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA19541-4","display" : "High risk"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15   : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-cibuild for validation purposes\r\n15 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n15 0    : 0ms  : Prepare include: \"(http://loinc.org)(LA10315-2,LA25391-6,LA25390-8,LA10317-8,LA9657-3,LA19542-2,LA19541-4,LA6676-6,LA6677-4,LA9660-7,LA9661-5,LA6682-4,LA6675-8,LA6674-1,LA9662-3,LA25392-4,LA25393-2,LA25395-7,LA25394-0)\"\r\n15 0    : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n15 0    : 0ms  : Prepare include: \"(http://snomed.info/sct)(444734003,399223003)\"\r\n15 0    : 0ms  : CodeSystem found: \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\"\r\n15 0    : 0ms  : Validate \"[http://loinc.org#LA19541-4 (\"High risk\")]\"\r\n15 0    : 0ms  : Check \"http://loinc.org#LA19541-4\"\r\n15 0    : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n15 0    : 0ms  : check code in (http://loinc.org)(LA10315-2,LA25391-6,LA25390-8,LA10317-8,LA9657-3,LA19542-2,LA19541-4,LA6676-6,LA6677-4,LA9660-7,LA9661-5,LA6682-4,LA6675-8,LA6674-1,LA9662-3,LA25392-4,LA25393-2,LA25395-7,LA25394-0) at CodeableConcept.coding[0]\r\n15 0    : 0ms  : Code \"LA19541-4\" found in http://loinc.org|2.81\r\n"}]}

#601

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","code":"14909","display":"HLA-B*15:02"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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date:Fri, 30 Jan 2026 18:33:58 GMT
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x-request-id:def73f40-95d0-4e20-9cc5-82f09a5f7084
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"14909"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/clinvar"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/clinvar was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/clinvar"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/clinvar was not found"}]}

#602

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"51969-4"},{"system":"http://loinc.org","code":"57979-7","display":"HLA-B*15:02 [Presence]"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"report-codes","meta":{"lastUpdated":"2019-11-01T09:29:23.356+11:00","profile":["http://hl7.org/fhir/StructureDefinition/shareablevalueset"]},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"oo"}],"url":"http://hl7.org/fhir/ValueSet/report-codes","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.233"}],"version":"4.0.1","name":"LOINCDiagnosticReportCodes","title":"LOINC Diagnostic Report Codes","status":"draft","experimental":false,"date":"2019-11-01T09:29:23+11:00","publisher":"FHIR Project team","contact":[{"telecom":[{"system":"url","value":"http://hl7.org/fhir"}]}],"description":"This value set includes LOINC codes that relate to Diagnostic Observations.","copyright":"This content from LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use.","compose":{"include":[{"system":"http://loinc.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1543
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:58 GMT
last-modified:Fri, 30 Jan 2026 18:33:58 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574137

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "57979-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "HLA-B*15:02 [Presence]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "51969-4"},{"system" : "http://loinc.org","code" : "57979-7","display" : "HLA-B*15:02 [Presence]"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/report-codes|4.0.1 for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"(http://loinc.org)\"\r\n16 0    : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n16 0    : 0ms  : Validate \"[http://loinc.org#51969-4 (\"\"), http://loinc.org#57979-7 (\"HLA-B*15:02 [Presence]\")]\"\r\n16 0    : 0ms  : Check \"http://loinc.org#51969-4\"\r\n16 0    : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0    : 0ms  : check code in (http://loinc.org) at CodeableConcept.coding[0]\r\n16 0    : 0ms  : Code \"51969-4\" found in http://loinc.org|2.81\r\n16 0    : 0ms  : Check \"http://loinc.org#57979-7\"\r\n16 0    : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0    : 0ms  : check code in (http://loinc.org) at CodeableConcept.coding[1]\r\n16 0    : 0ms  : Code \"57979-7\" found in http://loinc.org|2.81\r\n"}]}

#603

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"51969-4"},{"system":"http://example.org/hgsc.bcm.edu/lab-test-codes/","code":"emerge-seq-ngs-pnl"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"report-codes","meta":{"lastUpdated":"2019-11-01T09:29:23.356+11:00","profile":["http://hl7.org/fhir/StructureDefinition/shareablevalueset"]},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"oo"}],"url":"http://hl7.org/fhir/ValueSet/report-codes","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.233"}],"version":"4.0.1","name":"LOINCDiagnosticReportCodes","title":"LOINC Diagnostic Report Codes","status":"draft","experimental":false,"date":"2019-11-01T09:29:23+11:00","publisher":"FHIR Project team","contact":[{"telecom":[{"system":"url","value":"http://hl7.org/fhir"}]}],"description":"This value set includes LOINC codes that relate to Diagnostic Observations.","copyright":"This content from LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use.","compose":{"include":[{"system":"http://loinc.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2896
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:33:58 GMT
last-modified:Fri, 30 Jan 2026 18:33:58 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574142

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://example.org/hgsc.bcm.edu/lab-test-codes/"},{"name" : "code","valueCode" : "51969-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic analysis report"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://example.org/hgsc.bcm.edu/lab-test-codes/' could not be found, so the code cannot be validated"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "51969-4"},{"system" : "http://example.org/hgsc.bcm.edu/lab-test-codes/","code" : "emerge-seq-ngs-pnl"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://example.org/hgsc.bcm.edu/lab-test-codes/#emerge-seq-ngs-pnl' was not found in the value set 'http://hl7.org/fhir/ValueSet/report-codes|4.0.1'"},"location" : ["CodeableConcept.coding[1].code"],"expression" : ["CodeableConcept.coding[1].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://example.org/hgsc.bcm.edu/lab-test-codes/' could not be found, so the code cannot be validated"},"location" : ["CodeableConcept.coding[1].system"],"expression" : ["CodeableConcept.coding[1].system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/report-codes|4.0.1 for validation purposes\r\n15 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n15 0    : 0ms  : Prepare include: \"(http://loinc.org)\"\r\n15 0    : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n15 0    : 0ms  : Validate \"[http://loinc.org#51969-4 (\"\"), http://example.org/hgsc.bcm.edu/lab-test-codes/#emerge-seq-ngs-pnl (\"\")]\"\r\n15 0    : 0ms  : Check \"http://loinc.org#51969-4\"\r\n15 0    : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n15 0    : 0ms  : check code in (http://loinc.org) at CodeableConcept.coding[0]\r\n15 0    : 0ms  : Code \"51969-4\" found in http://loinc.org|2.81\r\n15 0    : 0ms  : Check \"http://example.org/hgsc.bcm.edu/lab-test-codes/#emerge-seq-ngs-pnl\"\r\n"}]}

#604

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","code":"638797","display":"CYP2C19*2/*2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:33:59 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:796c9dcc-5e81-44b4-ad3f-193238a7d587
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:796c9dcc-5e81-44b4-ad3f-193238a7d587
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"638797"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/clinvar"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/clinvar was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/clinvar"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/clinvar was not found"}]}

#605

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","code":"638797","display":"CYP2C19*2/*2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:33:59 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:61e99139-1127-4c7a-a331-73bd599759d0
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:61e99139-1127-4c7a-a331-73bd599759d0
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"638797"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/clinvar"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/clinvar was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/clinvar"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/clinvar was not found"}]}

#606

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:2621","display":"CYP2C19"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:34:00 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:1ef4ffff-2176-4fe0-aab8-c51084425f19
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:1ef4ffff-2176-4fe0-aab8-c51084425f19
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:2621"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#607

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:2621"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:34:00 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:cbc888af-3643-4601-9545-b1882536b920
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x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:cbc888af-3643-4601-9545-b1882536b920
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:2621"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}]}

#608

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:2621","display":"CYP2C19"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:34:01 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:e4de7a08-621d-43bc-8048-d19405f61af5
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x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:e4de7a08-621d-43bc-8048-d19405f61af5
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:2621"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#609

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10","display":"b37 Chr10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:34:01 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:ffef46cb-9d47-4aa4-b804-410eb91503ad
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:ffef46cb-9d47-4aa4-b804-410eb91503ad
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#610

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA30102-0","display":"1-based character counting"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:952
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:03 GMT
last-modified:Fri, 30 Jan 2026 18:34:03 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574190

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA30102-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "1-based character counting"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA30102-0","display" : "1-based character counting"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA30102-0 (\"1-based character counting\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA30102-0\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#611

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:262","display":"CYP2C19"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:34:03 GMT
server:nginx
vary:Origin
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vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
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x-request-id:b1751ac2-c6db-48cb-bc40-558d7c85ab07
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:262"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#612

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:262"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:34:04 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
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vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
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x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:262"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}]}

#613

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:262","display":"CYP2C19"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:34:04 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:db620e94-531d-4955-9c76-59bdcfcae570
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x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:db620e94-531d-4955-9c76-59bdcfcae570
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:262"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#614

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0002073","display":"wild type"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:34:05 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:3a3c8cd1-8481-4d01-8ddb-0caa6992c3eb
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x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:3a3c8cd1-8481-4d01-8ddb-0caa6992c3eb
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0002073"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#615

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA30102-0","display":"1-based character counting"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL5323-2","name":"LOINCAnswersLL5323-2","title":"LOINC Answer Codes for LL5323-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL5323-2"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1235
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:07 GMT
last-modified:Fri, 30 Jan 2026 18:34:07 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574245

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA30102-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "1-based character counting"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA30102-0","display" : "1-based character counting"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15   : 0ms  : Analysing http://loinc.org/vs/LL5323-2 for validation purposes\r\n15 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n15 0    : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL5323-2)\"\r\n15 0    : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n15 0    : 0ms  : Validate \"[http://loinc.org#LA30102-0 (\"1-based character counting\")]\"\r\n15 0    : 0ms  : Check \"http://loinc.org#LA30102-0\"\r\n15 0    : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n15 0    : 0ms  : check code in (http://loinc.org)(LIST=LL5323-2) at CodeableConcept.coding[0]\r\n2047 2032: 2032ms : Filter \"LIST=LL5323-2\": Code \"LA30102-0\" found in http://loinc.org|2.81\r\n"}]}

#616

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0002073","display":"wild type"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:34:08 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:7f710f1c-3a12-40be-aac2-5f53825f31f8
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:7f710f1c-3a12-40be-aac2-5f53825f31f8
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0002073"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#617

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0002073"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0002072"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:34:08 GMT
server:nginx
vary:Origin
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x-request-id:294e7e17-3106-46b2-b66b-9a1fd67062d1
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0002073"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}]}

#618

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000010.10:g.96540410G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
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cache-control:public, max-age=600
connection:keep-alive
content-length:844
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:08 GMT
last-modified:Fri, 30 Jan 2026 18:34:08 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574299

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000010.10:g.96540410G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000010.10:g.96540410G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000010.10:g.96540410G>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000010.10:g.96540410G>A\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#619

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000010.10:g.96540410G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1151
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:09 GMT
last-modified:Fri, 30 Jan 2026 18:34:09 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574305

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000010.10:g.96540410G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000010.10:g.96540410G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000010.10:g.96540410G>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000010.10:g.96540410G>A\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n63 63   : 63ms : Code \"NC_000010.10:g.96540410G>A\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#620

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:1000002","display":"wild type"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:34:09 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:f603338e-51bd-4ddc-9405-042fd072f70a
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:f603338e-51bd-4ddc-9405-042fd072f70a
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:1000002"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#621

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:1000002","display":"wild type"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:34:10 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:f7ff0169-cec0-480c-9b83-120ce47f91aa
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:f7ff0169-cec0-480c-9b83-120ce47f91aa
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:1000002"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#622

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:1000002"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0002072"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:34:10 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:337b15d2-79bf-4c2c-8c19-5e2dce618c0c
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:337b15d2-79bf-4c2c-8c19-5e2dce618c0c
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:1000002"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}]}

#623

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://www.nlm.nih.gov/research/umls/rxnorm","code":"32968","display":"clopidogrel"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1022
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:11 GMT
last-modified:Fri, 30 Jan 2026 18:34:11 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574339

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://www.nlm.nih.gov/research/umls/rxnorm"},{"name" : "code","valueCode" : "32968"},{"name" : "version","valueString" : "??"},{"name" : "display","valueString" : "clopidogrel"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://www.nlm.nih.gov/research/umls/rxnorm","code" : "32968","display" : "clopidogrel"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.nlm.nih.gov/research/umls/rxnorm#32968 (\"clopidogrel\")]\"\r\n0 0     : 0ms  : Check \"http://www.nlm.nih.gov/research/umls/rxnorm#32968\"\r\n0 0     : 0ms  : Using CodeSystem \"http://www.nlm.nih.gov/research/umls/rxnorm|??\" (content = complete)\r\n"}]}

#624

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA9657-3","display":"Poor metabolizer"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:918
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:12 GMT
last-modified:Fri, 30 Jan 2026 18:34:12 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574340

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA9657-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Poor metabolizer"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA9657-3","display" : "Poor metabolizer"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA9657-3 (\"Poor metabolizer\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA9657-3\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#625

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA9657-3","display":"Poor metabolizer"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"genetic-therapeutic-implications-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs","version":"4.0.0-cibuild","name":"GeneticTherapeuticImplicationsVS","title":"Genetic Therapeutic Implications","status":"active","experimental":false,"date":"2026-01-30T18:21:39+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for terms that describe a predicted ramification based on the presence of associated molecular finding(s).","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This material contains content from LOINC (http://loinc.org). LOINC is copyright © 1995-2020, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC® is a registered United States trademark of Regenstrief Institute, Inc.\nThis value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement.","compose":{"include":[{"system":"http://loinc.org","concept":[{"code":"LA10315-2","display":"Ultrarapid metabolizer"},{"code":"LA25391-6","display":"Normal metabolizer"},{"code":"LA25390-8","display":"Rapid metabolizer"},{"code":"LA10317-8","display":"Intermediate metabolizer"},{"code":"LA9657-3","display":"Poor metabolizer"},{"code":"LA19542-2","display":"Low Risk"},{"code":"LA19541-4","display":"High Risk"},{"code":"LA6676-6","display":"Resistant"},{"code":"LA6677-4","display":"Responsive"},{"code":"LA9660-7","display":"Presumed resistant"},{"code":"LA9661-5","display":"Presumed responsive"},{"code":"LA6682-4","display":"Unknown Significance"},{"code":"LA6675-8","display":"Benign"},{"code":"LA6674-1","display":"Presumed Benign"},{"code":"LA9662-3","display":"Presumed non-responsive"},{"code":"LA25392-4","display":"Increased function"},{"code":"LA25393-2","display":"Normal function"},{"code":"LA25395-7","display":"Decreased function"},{"code":"LA25394-0","display":"Poor function"}]},{"system":"http://snomed.info/sct","concept":[{"code":"444734003","display":"Does not meet eligibility criteria for clinical trial (finding)"},{"code":"399223003","display":"Patient eligible for clinical trial (finding)"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1788
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:12 GMT
last-modified:Fri, 30 Jan 2026 18:34:12 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574362

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA9657-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Poor metabolizer"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA9657-3","display" : "Poor metabolizer"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n31 31   : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-cibuild for validation purposes\r\n31 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n31 0    : 0ms  : Prepare include: \"(http://loinc.org)(LA10315-2,LA25391-6,LA25390-8,LA10317-8,LA9657-3,LA19542-2,LA19541-4,LA6676-6,LA6677-4,LA9660-7,LA9661-5,LA6682-4,LA6675-8,LA6674-1,LA9662-3,LA25392-4,LA25393-2,LA25395-7,LA25394-0)\"\r\n31 0    : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n31 0    : 0ms  : Prepare include: \"(http://snomed.info/sct)(444734003,399223003)\"\r\n31 0    : 0ms  : CodeSystem found: \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\"\r\n31 0    : 0ms  : Validate \"[http://loinc.org#LA9657-3 (\"Poor metabolizer\")]\"\r\n31 0    : 0ms  : Check \"http://loinc.org#LA9657-3\"\r\n31 0    : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n31 0    : 0ms  : check code in (http://loinc.org)(LA10315-2,LA25391-6,LA25390-8,LA10317-8,LA9657-3,LA19542-2,LA19541-4,LA6676-6,LA6677-4,LA9660-7,LA9661-5,LA6682-4,LA6675-8,LA6674-1,LA9662-3,LA25392-4,LA25393-2,LA25395-7,LA25394-0) at CodeableConcept.coding[0]\r\n31 0    : 0ms  : Code \"LA9657-3\" found in http://loinc.org|2.81\r\n"}]}

#626

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://www.nlm.nih.gov/research/umls/rxnorm","code":"121243","display":"voriconazole"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1029
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:12 GMT
last-modified:Fri, 30 Jan 2026 18:34:12 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574366

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://www.nlm.nih.gov/research/umls/rxnorm"},{"name" : "code","valueCode" : "121243"},{"name" : "version","valueString" : "??"},{"name" : "display","valueString" : "voriconazole"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://www.nlm.nih.gov/research/umls/rxnorm","code" : "121243","display" : "voriconazole"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.nlm.nih.gov/research/umls/rxnorm#121243 (\"voriconazole\")]\"\r\n0 0     : 0ms  : Check \"http://www.nlm.nih.gov/research/umls/rxnorm#121243\"\r\n0 0     : 0ms  : Using CodeSystem \"http://www.nlm.nih.gov/research/umls/rxnorm|??\" (content = complete)\r\n"}]}

#627

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://www.nlm.nih.gov/research/umls/rxnorm","code":"2556","display":"citalopram"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1015
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:13 GMT
last-modified:Fri, 30 Jan 2026 18:34:13 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574369

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://www.nlm.nih.gov/research/umls/rxnorm"},{"name" : "code","valueCode" : "2556"},{"name" : "version","valueString" : "??"},{"name" : "display","valueString" : "citalopram"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://www.nlm.nih.gov/research/umls/rxnorm","code" : "2556","display" : "citalopram"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.nlm.nih.gov/research/umls/rxnorm#2556 (\"citalopram\")]\"\r\n0 0     : 0ms  : Check \"http://www.nlm.nih.gov/research/umls/rxnorm#2556\"\r\n0 0     : 0ms  : Using CodeSystem \"http://www.nlm.nih.gov/research/umls/rxnorm|??\" (content = complete)\r\n"}]}

#628

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://www.nlm.nih.gov/research/umls/rxnorm","code":"321988","display":"escitalopram"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1029
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:13 GMT
last-modified:Fri, 30 Jan 2026 18:34:13 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574372

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://www.nlm.nih.gov/research/umls/rxnorm"},{"name" : "code","valueCode" : "321988"},{"name" : "version","valueString" : "??"},{"name" : "display","valueString" : "escitalopram"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://www.nlm.nih.gov/research/umls/rxnorm","code" : "321988","display" : "escitalopram"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.nlm.nih.gov/research/umls/rxnorm#321988 (\"escitalopram\")]\"\r\n0 0     : 0ms  : Check \"http://www.nlm.nih.gov/research/umls/rxnorm#321988\"\r\n0 0     : 0ms  : Using CodeSystem \"http://www.nlm.nih.gov/research/umls/rxnorm|??\" (content = complete)\r\n"}]}

#629

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://www.nlm.nih.gov/research/umls/rxnorm","code":"704","display":"amitriptyline"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1020
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:13 GMT
last-modified:Fri, 30 Jan 2026 18:34:13 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574374

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://www.nlm.nih.gov/research/umls/rxnorm"},{"name" : "code","valueCode" : "704"},{"name" : "version","valueString" : "??"},{"name" : "display","valueString" : "amitriptyline"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://www.nlm.nih.gov/research/umls/rxnorm","code" : "704","display" : "amitriptyline"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.nlm.nih.gov/research/umls/rxnorm#704 (\"amitriptyline\")]\"\r\n0 0     : 0ms  : Check \"http://www.nlm.nih.gov/research/umls/rxnorm#704\"\r\n0 0     : 0ms  : Using CodeSystem \"http://www.nlm.nih.gov/research/umls/rxnorm|??\" (content = complete)\r\n"}]}

#630

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000016.9:g.31096368G>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:840
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:13 GMT
last-modified:Fri, 30 Jan 2026 18:34:13 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574378

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000016.9:g.31096368G>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000016.9:g.31096368G>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000016.9:g.31096368G>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000016.9:g.31096368G>T\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#631

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000016.9:g.31096368G>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1146
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:13 GMT
last-modified:Fri, 30 Jan 2026 18:34:13 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574381

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000016.9:g.31096368G>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000016.9:g.31096368G>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000016.9:g.31096368G>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000016.9:g.31096368G>T\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n78 78   : 78ms : Code \"NC_000016.9:g.31096368G>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#632

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://www.nlm.nih.gov/research/umls/rxnorm","code":"11289","display":"warfarin"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1013
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:13 GMT
last-modified:Fri, 30 Jan 2026 18:34:13 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574387

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://www.nlm.nih.gov/research/umls/rxnorm"},{"name" : "code","valueCode" : "11289"},{"name" : "version","valueString" : "??"},{"name" : "display","valueString" : "warfarin"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://www.nlm.nih.gov/research/umls/rxnorm","code" : "11289","display" : "warfarin"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.nlm.nih.gov/research/umls/rxnorm#11289 (\"warfarin\")]\"\r\n0 0     : 0ms  : Check \"http://www.nlm.nih.gov/research/umls/rxnorm#11289\"\r\n0 0     : 0ms  : Using CodeSystem \"http://www.nlm.nih.gov/research/umls/rxnorm|??\" (content = complete)\r\n"}]}

#633

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA25391-6","display":"Normal metabolizer"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:928
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:15 GMT
last-modified:Fri, 30 Jan 2026 18:34:15 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574388

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA25391-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Normal metabolizer"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA25391-6","display" : "Normal metabolizer"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA25391-6 (\"Normal metabolizer\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA25391-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#634

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA25391-6","display":"Normal metabolizer"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"genetic-therapeutic-implications-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs","version":"4.0.0-cibuild","name":"GeneticTherapeuticImplicationsVS","title":"Genetic Therapeutic Implications","status":"active","experimental":false,"date":"2026-01-30T18:21:39+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for terms that describe a predicted ramification based on the presence of associated molecular finding(s).","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This material contains content from LOINC (http://loinc.org). LOINC is copyright © 1995-2020, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC® is a registered United States trademark of Regenstrief Institute, Inc.\nThis value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement.","compose":{"include":[{"system":"http://loinc.org","concept":[{"code":"LA10315-2","display":"Ultrarapid metabolizer"},{"code":"LA25391-6","display":"Normal metabolizer"},{"code":"LA25390-8","display":"Rapid metabolizer"},{"code":"LA10317-8","display":"Intermediate metabolizer"},{"code":"LA9657-3","display":"Poor metabolizer"},{"code":"LA19542-2","display":"Low Risk"},{"code":"LA19541-4","display":"High Risk"},{"code":"LA6676-6","display":"Resistant"},{"code":"LA6677-4","display":"Responsive"},{"code":"LA9660-7","display":"Presumed resistant"},{"code":"LA9661-5","display":"Presumed responsive"},{"code":"LA6682-4","display":"Unknown Significance"},{"code":"LA6675-8","display":"Benign"},{"code":"LA6674-1","display":"Presumed Benign"},{"code":"LA9662-3","display":"Presumed non-responsive"},{"code":"LA25392-4","display":"Increased function"},{"code":"LA25393-2","display":"Normal function"},{"code":"LA25395-7","display":"Decreased function"},{"code":"LA25394-0","display":"Poor function"}]},{"system":"http://snomed.info/sct","concept":[{"code":"444734003","display":"Does not meet eligibility criteria for clinical trial (finding)"},{"code":"399223003","display":"Patient eligible for clinical trial (finding)"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1799
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:15 GMT
last-modified:Fri, 30 Jan 2026 18:34:15 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574404

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA25391-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Normal metabolizer"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA25391-6","display" : "Normal metabolizer"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-cibuild for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"(http://loinc.org)(LA10315-2,LA25391-6,LA25390-8,LA10317-8,LA9657-3,LA19542-2,LA19541-4,LA6676-6,LA6677-4,LA9660-7,LA9661-5,LA6682-4,LA6675-8,LA6674-1,LA9662-3,LA25392-4,LA25393-2,LA25395-7,LA25394-0)\"\r\n16 0    : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n16 0    : 0ms  : Prepare include: \"(http://snomed.info/sct)(444734003,399223003)\"\r\n16 0    : 0ms  : CodeSystem found: \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\"\r\n16 0    : 0ms  : Validate \"[http://loinc.org#LA25391-6 (\"Normal metabolizer\")]\"\r\n16 0    : 0ms  : Check \"http://loinc.org#LA25391-6\"\r\n31 15   : 15ms : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n31 0    : 15ms : check code in (http://loinc.org)(LA10315-2,LA25391-6,LA25390-8,LA10317-8,LA9657-3,LA19542-2,LA19541-4,LA6676-6,LA6677-4,LA9660-7,LA9661-5,LA6682-4,LA6675-8,LA6674-1,LA9662-3,LA25392-4,LA25393-2,LA25395-7,LA25394-0) at CodeableConcept.coding[0]\r\n31 0    : 15ms : Code \"LA25391-6\" found in http://loinc.org|2.81\r\n"}]}

#635

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","code":"638797","display":"CYP2C19*2/*2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:34:17 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:9f1f449f-beaf-4225-8d0e-6d0340db6a92
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:9f1f449f-beaf-4225-8d0e-6d0340db6a92
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"638797"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/clinvar"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/clinvar was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/clinvar"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/clinvar was not found"}]}

#636

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"51969-4"},{"system":"http://example.org/hgsc.bcm.edu/lab-test-codes/","code":"emerge-seq-ngs-pnl"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"report-codes","meta":{"lastUpdated":"2019-11-01T09:29:23.356+11:00","profile":["http://hl7.org/fhir/StructureDefinition/shareablevalueset"]},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"oo"}],"url":"http://hl7.org/fhir/ValueSet/report-codes","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.233"}],"version":"4.0.1","name":"LOINCDiagnosticReportCodes","title":"LOINC Diagnostic Report Codes","status":"draft","experimental":false,"date":"2019-11-01T09:29:23+11:00","publisher":"FHIR Project team","contact":[{"telecom":[{"system":"url","value":"http://hl7.org/fhir"}]}],"description":"This value set includes LOINC codes that relate to Diagnostic Observations.","copyright":"This content from LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use.","compose":{"include":[{"system":"http://loinc.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2896
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:18 GMT
last-modified:Fri, 30 Jan 2026 18:34:18 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574440

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://example.org/hgsc.bcm.edu/lab-test-codes/"},{"name" : "code","valueCode" : "51969-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic analysis report"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://example.org/hgsc.bcm.edu/lab-test-codes/' could not be found, so the code cannot be validated"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "51969-4"},{"system" : "http://example.org/hgsc.bcm.edu/lab-test-codes/","code" : "emerge-seq-ngs-pnl"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://example.org/hgsc.bcm.edu/lab-test-codes/#emerge-seq-ngs-pnl' was not found in the value set 'http://hl7.org/fhir/ValueSet/report-codes|4.0.1'"},"location" : ["CodeableConcept.coding[1].code"],"expression" : ["CodeableConcept.coding[1].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://example.org/hgsc.bcm.edu/lab-test-codes/' could not be found, so the code cannot be validated"},"location" : ["CodeableConcept.coding[1].system"],"expression" : ["CodeableConcept.coding[1].system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/report-codes|4.0.1 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#51969-4 (\"\"), http://example.org/hgsc.bcm.edu/lab-test-codes/#emerge-seq-ngs-pnl (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#51969-4\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org) at CodeableConcept.coding[0]\r\n0 0     : 0ms  : Code \"51969-4\" found in http://loinc.org|2.81\r\n0 0     : 0ms  : Check \"http://example.org/hgsc.bcm.edu/lab-test-codes/#emerge-seq-ngs-pnl\"\r\n"}]}

#637

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"84414-2","display":"Haplotype name"},{"system":"http://loinc.org","code":"57290-9","display":"HLA-A [Type] by High resolution"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1230
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:20 GMT
last-modified:Fri, 30 Jan 2026 18:34:20 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574444

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "57290-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "HLA-A [Type] by High resolution"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "84414-2","display" : "Haplotype name"},{"system" : "http://loinc.org","code" : "57290-9","display" : "HLA-A [Type] by High resolution"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#84414-2 (\"Haplotype name\"), http://loinc.org#57290-9 (\"HLA-A [Type] by High resolution\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#84414-2\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n1359 1359: 1359ms : Check \"http://loinc.org#57290-9\"\r\n1359 0  : 1359ms : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#638

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","version":"3.31.0","code":"HLA-A*03:01:01:01"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1741
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:21 GMT
last-modified:Fri, 30 Jan 2026 18:34:21 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574489

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "HLA-A*03:01:01:01"},{"name" : "version","valueString" : "3.31.0"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.31.0' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.31.0' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla|3.31.0#HLA-A*03:01:01:01 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ebi.ac.uk/ipd/imgt/hla|3.31.0#HLA-A*03:01:01:01\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla|3.31.0\"\r\n"}]}

#639

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:4931","display":"HLA-A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:34:21 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:5f6154a8-8e8f-456d-8147-c827a7d43ec6
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:5f6154a8-8e8f-456d-8147-c827a7d43ec6
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:4931"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#640

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:4931"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:34:22 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:5d47d9e9-0f9e-403d-b214-65286ca07da5
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x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:5d47d9e9-0f9e-403d-b214-65286ca07da5
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:4931"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}]}

#641

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:4931","display":"HLA-A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:34:22 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:8de53274-cc7a-433e-a558-d86bb20fb6d3
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:8de53274-cc7a-433e-a558-d86bb20fb6d3
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:4931"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#642

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"84413-4","display":"Genotype display name"},{"system":"http://loinc.org","code":"57290-9","display":"HLA-A [Type] by High resolution"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1244
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:25 GMT
last-modified:Fri, 30 Jan 2026 18:34:25 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574515

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "57290-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "HLA-A [Type] by High resolution"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "84413-4","display" : "Genotype display name"},{"system" : "http://loinc.org","code" : "57290-9","display" : "HLA-A [Type] by High resolution"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#84413-4 (\"Genotype display name\"), http://loinc.org#57290-9 (\"HLA-A [Type] by High resolution\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#84413-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n1359 1359: 1359ms : Check \"http://loinc.org#57290-9\"\r\n1359 0  : 1359ms : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#643

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://glstring.org","version":"1.0","code":"hla#3.31.0#HLA-A*03:01:01:01+HLA-A*30:01:01"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1703
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:25 GMT
last-modified:Fri, 30 Jan 2026 18:34:25 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574550

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://glstring.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://glstring.org"},{"name" : "code","valueCode" : "hla#3.31.0#HLA-A*03:01:01:01+HLA-A*30:01:01"},{"name" : "version","valueString" : "1.0"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://glstring.org|1.0#hla#3.31.0#HLA-A*03:01:01:01+HLA-A*30:01:01 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://glstring.org|1.0#hla#3.31.0#HLA-A*03:01:01:01+HLA-A*30:01:01\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://glstring.org|1.0\"\r\n"}]}

#644

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_060087.3:p.A1931T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:820
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:25 GMT
last-modified:Fri, 30 Jan 2026 18:34:25 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574557

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_060087.3:p.A1931T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_060087.3:p.A1931T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_060087.3:p.A1931T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_060087.3:p.A1931T\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#645

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_017617.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:34:26 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:3200f24c-26c7-475f-a882-c260fbfaa989
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:3200f24c-26c7-475f-a882-c260fbfaa989
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NM_017617.5"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#646

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_017617.5:c.5791G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:824
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:26 GMT
last-modified:Fri, 30 Jan 2026 18:34:26 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574573

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_017617.5:c.5791G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_017617.5:c.5791G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_017617.5:c.5791G>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_017617.5:c.5791G>A\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#647

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:7881","display":"NOTCH1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:34:27 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:57ef74c6-9b68-442a-b0ec-47d2509731ac
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:57ef74c6-9b68-442a-b0ec-47d2509731ac
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:7881"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#648

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA21262-3","display":"Chromosome 9"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:910
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:28 GMT
last-modified:Fri, 30 Jan 2026 18:34:28 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574589

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA21262-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Chromosome 9"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA21262-3","display" : "Chromosome 9"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA21262-3 (\"Chromosome 9\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA21262-3\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#649

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000009.11"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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date:Fri, 30 Jan 2026 18:34:29 GMT
server:nginx
vary:Origin
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vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
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x-request-id:428b378d-2925-4808-bdad-3779f6663ea7
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000009.11"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#650

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000009.11:g.139395147C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:848
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:29 GMT
last-modified:Fri, 30 Jan 2026 18:34:29 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574625

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000009.11:g.139395147C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000009.11:g.139395147C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000009.11:g.139395147C>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000009.11:g.139395147C>T\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#651

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_060087.3:p.A1931T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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date:Fri, 30 Jan 2026 18:34:29 GMT
last-modified:Fri, 30 Jan 2026 18:34:29 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574627

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_060087.3:p.A1931T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_060087.3:p.A1931T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_060087.3:p.A1931T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_060087.3:p.A1931T\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n62 62   : 62ms : Code \"NP_060087.3:p.A1931T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#652

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_017617.5:c.5791G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1126
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:29 GMT
last-modified:Fri, 30 Jan 2026 18:34:29 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574631

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_017617.5:c.5791G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_017617.5:c.5791G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_017617.5:c.5791G>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_017617.5:c.5791G>A\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n78 78   : 78ms : Code \"NM_017617.5:c.5791G>A\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#653

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:7881","display":"NOTCH1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:34:30 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:0cdf4db8-eec5-43df-a46b-c95865a50224
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:0cdf4db8-eec5-43df-a46b-c95865a50224
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:7881"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#654

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:7881"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:34:30 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:30b87d54-0033-489d-b0c8-27c10d34ac53
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:30b87d54-0033-489d-b0c8-27c10d34ac53
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:7881"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}]}

#655

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA21262-3","display":"Chromosome 9"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL2938-0","name":"LOINCAnswersLL2938-0","title":"LOINC Answer Codes for LL2938-0","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL2938-0"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1193
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:33 GMT
last-modified:Fri, 30 Jan 2026 18:34:33 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574644

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA21262-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Chromosome 9"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA21262-3","display" : "Chromosome 9"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL2938-0 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL2938-0)\"\r\n15 15   : 15ms : CodeSystem found: \"http://loinc.org|2.81\"\r\n15 0    : 15ms : Validate \"[http://loinc.org#LA21262-3 (\"Chromosome 9\")]\"\r\n15 0    : 15ms : Check \"http://loinc.org#LA21262-3\"\r\n15 0    : 15ms : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n15 0    : 15ms : check code in (http://loinc.org)(LIST=LL2938-0) at CodeableConcept.coding[0]\r\n2015 2000: 2015ms : Filter \"LIST=LL2938-0\": Code \"LA21262-3\" found in http://loinc.org|2.81\r\n"}]}

#656

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000009.11:g.139395147C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1156
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:33 GMT
last-modified:Fri, 30 Jan 2026 18:34:33 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574678

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000009.11:g.139395147C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000009.11:g.139395147C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000009.11:g.139395147C>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000009.11:g.139395147C>T\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n62 62   : 62ms : Code \"NC_000009.11:g.139395147C>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#657

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_008816.3:p.G585S"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:816
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:33 GMT
last-modified:Fri, 30 Jan 2026 18:34:33 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574680

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_008816.3:p.G585S"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_008816.3:p.G585S"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_008816.3:p.G585S (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_008816.3:p.G585S\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#658

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_006885.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:34:33 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:37fd61e9-2fee-44bb-bde7-dea98d70fcf7
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:37fd61e9-2fee-44bb-bde7-dea98d70fcf7
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NM_006885.4"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#659

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_006885.4:c.1753G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:824
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:34 GMT
last-modified:Fri, 30 Jan 2026 18:34:34 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574694

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_006885.4:c.1753G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_006885.4:c.1753G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_006885.4:c.1753G>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_006885.4:c.1753G>A\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#660

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:777","display":"ZFHX3"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:34:34 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:028d5ecd-83b2-403f-b91f-af5815833a62
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:028d5ecd-83b2-403f-b91f-af5815833a62
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:777"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#661

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA21269-8","display":"Chromosome 16"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:913
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:36 GMT
last-modified:Fri, 30 Jan 2026 18:34:36 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574707

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA21269-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Chromosome 16"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA21269-8","display" : "Chromosome 16"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA21269-8 (\"Chromosome 16\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA21269-8\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#662

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000016.9"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:34:36 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:ee6af6bd-ca80-49d0-a39e-72b7671d8d33
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:ee6af6bd-ca80-49d0-a39e-72b7671d8d33
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000016.9"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#663

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000016.9:g.72992292C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:840
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:36 GMT
last-modified:Fri, 30 Jan 2026 18:34:36 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574745

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000016.9:g.72992292C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000016.9:g.72992292C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000016.9:g.72992292C>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000016.9:g.72992292C>T\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#664

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_008816.3:p.G585S"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1116
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:37 GMT
last-modified:Fri, 30 Jan 2026 18:34:37 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574748

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_008816.3:p.G585S"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_008816.3:p.G585S"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_008816.3:p.G585S (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_008816.3:p.G585S\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n78 78   : 78ms : Code \"NP_008816.3:p.G585S\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#665

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_006885.4:c.1753G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1126
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:37 GMT
last-modified:Fri, 30 Jan 2026 18:34:37 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574753

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_006885.4:c.1753G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_006885.4:c.1753G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n16 16   : 16ms : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n16 0    : 16ms : Validate \"[http://varnomen.hgvs.org#NM_006885.4:c.1753G>A (\"\")]\"\r\n16 0    : 16ms : Check \"http://varnomen.hgvs.org#NM_006885.4:c.1753G>A\"\r\n16 0    : 16ms : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n16 0    : 16ms : check code in (http://varnomen.hgvs.org) at Coding\r\n78 62   : 78ms : Code \"NM_006885.4:c.1753G>A\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#666

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:777","display":"ZFHX3"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:34:37 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:317a10d3-793c-45e9-a5b1-7b54ebd1934f
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:317a10d3-793c-45e9-a5b1-7b54ebd1934f
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:777"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#667

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:777"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:34:38 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:1702c888-ceb4-4688-9876-0a59024c983f
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:1702c888-ceb4-4688-9876-0a59024c983f
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:777"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}]}

#668

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA21269-8","display":"Chromosome 16"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL2938-0","name":"LOINCAnswersLL2938-0","title":"LOINC Answer Codes for LL2938-0","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL2938-0"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1196
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:40 GMT
last-modified:Fri, 30 Jan 2026 18:34:40 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574776

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA21269-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Chromosome 16"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA21269-8","display" : "Chromosome 16"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL2938-0 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL2938-0)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA21269-8 (\"Chromosome 16\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA21269-8\"\r\n16 16   : 16ms : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0    : 16ms : check code in (http://loinc.org)(LIST=LL2938-0) at CodeableConcept.coding[0]\r\n2016 2000: 2016ms : Filter \"LIST=LL2938-0\": Code \"LA21269-8\" found in http://loinc.org|2.81\r\n"}]}

#669

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000016.9:g.72992292C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1146
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:40 GMT
last-modified:Fri, 30 Jan 2026 18:34:40 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574808

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000016.9:g.72992292C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000016.9:g.72992292C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000016.9:g.72992292C>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000016.9:g.72992292C>T\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n78 78   : 78ms : Code \"NC_000016.9:g.72992292C>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#670

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:7235","display":"MSH2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:34:41 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:983a68b8-3bbd-4ea4-aefc-e9557de3876a
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:983a68b8-3bbd-4ea4-aefc-e9557de3876a
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:7235"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#671

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","code":"1780982","display":"NM_000251.3(MSH2):c.1832del (p.Val611fs)"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:34:41 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:12fc3cd1-032f-43fe-ac7a-45996fc9c0de
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:12fc3cd1-032f-43fe-ac7a-45996fc9c0de
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"1780982"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/clinvar"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/clinvar was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/clinvar"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/clinvar was not found"}]}

#672

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:7235","display":"MSH2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:34:42 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:b111e4a8-17eb-4c0f-8e50-631108460227
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:b111e4a8-17eb-4c0f-8e50-631108460227
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:7235"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#673

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:7235"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:34:42 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:14c29085-4860-451b-bb3c-a5b5bc614fa8
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:14c29085-4860-451b-bb3c-a5b5bc614fa8
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:7235"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}]}

#674

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_002519.2:p.Trp243Ter"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:832
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:42 GMT
last-modified:Fri, 30 Jan 2026 18:34:42 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574849

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_002519.2:p.Trp243Ter"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_002519.2:p.Trp243Ter"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_002519.2:p.Trp243Ter (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_002519.2:p.Trp243Ter\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#675

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001483","display":"SNV"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:34:43 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:b092d38c-b028-4617-bf3e-70bfd69d7a89
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:b092d38c-b028-4617-bf3e-70bfd69d7a89
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001483"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#676

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_002528.7:c.728G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:820
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:43 GMT
last-modified:Fri, 30 Jan 2026 18:34:43 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574860

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_002528.7:c.728G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_002528.7:c.728G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_002528.7:c.728G>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_002528.7:c.728G>A\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#677

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:8028","display":"NTHL1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:34:44 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:71d1bfb6-2e21-41ad-acb5-8f96765474a5
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:71d1bfb6-2e21-41ad-acb5-8f96765474a5
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:8028"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#678

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","code":"962538","display":"NM_002528.7(NTHL1):c.728G>A (p.Trp243Ter)"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:34:44 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:1666326f-1b1d-44b2-aa3c-c363d21764ce
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:1666326f-1b1d-44b2-aa3c-c363d21764ce
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"962538"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/clinvar"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/clinvar was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/clinvar"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/clinvar was not found"}]}

#679

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000016.10:g.2040196C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:840
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:44 GMT
last-modified:Fri, 30 Jan 2026 18:34:44 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574886

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000016.10:g.2040196C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000016.10:g.2040196C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000016.10:g.2040196C>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000016.10:g.2040196C>T\"\r\n16 16   : 16ms : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#680

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_002519.2:p.Trp243Ter"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1136
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:45 GMT
last-modified:Fri, 30 Jan 2026 18:34:45 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574891

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_002519.2:p.Trp243Ter"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_002519.2:p.Trp243Ter"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_002519.2:p.Trp243Ter (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_002519.2:p.Trp243Ter\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n63 63   : 63ms : Code \"NP_002519.2:p.Trp243Ter\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#681

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001483","display":"SNV"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:34:45 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:94edf785-2bc0-4977-886d-2039e90ad9b6
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:94edf785-2bc0-4977-886d-2039e90ad9b6
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001483"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#682

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001483"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0002072"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:34:46 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:43194886-10e7-4b35-9aef-c7867d1070a9
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:43194886-10e7-4b35-9aef-c7867d1070a9
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001483"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}]}

#683

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_002528.7:c.728G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1121
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:46 GMT
last-modified:Fri, 30 Jan 2026 18:34:46 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574912

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_002528.7:c.728G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_002528.7:c.728G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_002528.7:c.728G>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_002528.7:c.728G>A\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n78 78   : 78ms : Code \"NM_002528.7:c.728G>A\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#684

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:8028","display":"NTHL1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:34:46 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:fed72828-a678-423e-9ce8-9b6ce61ea1f4
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:fed72828-a678-423e-9ce8-9b6ce61ea1f4
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:8028"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#685

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:8028"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:34:47 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:d80112b9-7d40-4164-92a0-481e9d62f3de
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:d80112b9-7d40-4164-92a0-481e9d62f3de
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:8028"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}]}

#686

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000016.10:g.2040196C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1146
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:47 GMT
last-modified:Fri, 30 Jan 2026 18:34:47 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574930

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000016.10:g.2040196C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000016.10:g.2040196C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000016.10:g.2040196C>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000016.10:g.2040196C>T\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n78 78   : 78ms : Code \"NC_000016.10:g.2040196C>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#687

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_006594.3:p.S1178*"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:820
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:47 GMT
last-modified:Fri, 30 Jan 2026 18:34:47 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574935

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_006594.3:p.S1178*"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_006594.3:p.S1178*"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_006594.3:p.S1178* (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_006594.3:p.S1178*\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#688

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_006603.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:34:48 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:b96998f9-a728-4cab-a8f3-869b87702ee4
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:b96998f9-a728-4cab-a8f3-869b87702ee4
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NM_006603.5"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#689

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0000667","display":"insertion"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:34:48 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:00ae76a5-6b11-4c59-9ace-d015fb60a190
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:00ae76a5-6b11-4c59-9ace-d015fb60a190
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0000667"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#690

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_006603.5:c.3530_3531insGTGACTATTAATAT"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:900
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:49 GMT
last-modified:Fri, 30 Jan 2026 18:34:49 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574958

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_006603.5:c.3530_3531insGTGACTATTAATAT"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_006603.5:c.3530_3531insGTGACTATTAATAT"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_006603.5:c.3530_3531insGTGACTATTAATAT (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_006603.5:c.3530_3531insGTGACTATTAATAT\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#691

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:11355","display":"STAG2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:34:49 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:579d3165-9e33-4b74-86d7-7afea89874e4
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:579d3165-9e33-4b74-86d7-7afea89874e4
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:11355"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#692

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA21276-3","display":"Chromosome X"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:910
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:51 GMT
last-modified:Fri, 30 Jan 2026 18:34:51 GMT
pragma:no-cache
server:nginx
x-request-id:253-23574975

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA21276-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Chromosome X"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA21276-3","display" : "Chromosome X"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA21276-3 (\"Chromosome X\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA21276-3\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#693

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000023.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:34:51 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:be755557-6fa0-45ad-b9f4-873a1ff0e52d
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:be755557-6fa0-45ad-b9f4-873a1ff0e52d
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000023.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#694

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000023.10:g.123227930_123227931insGTGACTATTAATAT"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:944
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:51 GMT
last-modified:Fri, 30 Jan 2026 18:34:51 GMT
pragma:no-cache
server:nginx
x-request-id:253-23575010

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000023.10:g.123227930_123227931insGTGACTATTAATAT"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000023.10:g.123227930_123227931insGTGACTATTAATAT"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000023.10:g.123227930_123227931insGTGACTATTAATAT (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000023.10:g.123227930_123227931insGTGACTATTAATAT\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#695

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_006594.3:p.S1178*"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1121
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:52 GMT
last-modified:Fri, 30 Jan 2026 18:34:52 GMT
pragma:no-cache
server:nginx
x-request-id:253-23575013

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_006594.3:p.S1178*"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_006594.3:p.S1178*"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_006594.3:p.S1178* (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_006594.3:p.S1178*\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n62 62   : 62ms : Code \"NP_006594.3:p.S1178*\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#696

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0000667","display":"insertion"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:34:52 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:fc545f5b-6e78-497e-981d-0183e5eb0a51
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:fc545f5b-6e78-497e-981d-0183e5eb0a51
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0000667"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#697

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0000667"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0002072"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:34:53 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:1d4d666b-0645-49c9-afce-80103e988914
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:1d4d666b-0645-49c9-afce-80103e988914
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0000667"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}]}

#698

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_006603.5:c.3530_3531insGTGACTATTAATAT"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1221
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:53 GMT
last-modified:Fri, 30 Jan 2026 18:34:53 GMT
pragma:no-cache
server:nginx
x-request-id:253-23575034

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_006603.5:c.3530_3531insGTGACTATTAATAT"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_006603.5:c.3530_3531insGTGACTATTAATAT"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_006603.5:c.3530_3531insGTGACTATTAATAT (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_006603.5:c.3530_3531insGTGACTATTAATAT\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n79 79   : 79ms : Code \"NM_006603.5:c.3530_3531insGTGACTATTAATAT\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#699

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:11355","display":"STAG2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:34:53 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:d8af1d98-31ea-4a00-bd2d-0e1886a0d4fb
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:d8af1d98-31ea-4a00-bd2d-0e1886a0d4fb
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:11355"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#700

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:11355"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:34:54 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:ef61b046-711a-4af1-8ac6-1fdcdecbeaf4
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:ef61b046-711a-4af1-8ac6-1fdcdecbeaf4
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:11355"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}]}

#701

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA21276-3","display":"Chromosome X"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL2938-0","name":"LOINCAnswersLL2938-0","title":"LOINC Answer Codes for LL2938-0","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL2938-0"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1193
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:56 GMT
last-modified:Fri, 30 Jan 2026 18:34:56 GMT
pragma:no-cache
server:nginx
x-request-id:253-23575056

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA21276-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Chromosome X"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA21276-3","display" : "Chromosome X"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL2938-0 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL2938-0)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA21276-3 (\"Chromosome X\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA21276-3\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL2938-0) at CodeableConcept.coding[0]\r\n2000 2000: 2000ms : Filter \"LIST=LL2938-0\": Code \"LA21276-3\" found in http://loinc.org|2.81\r\n"}]}

#702

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000023.10:g.123227930_123227931insGTGACTATTAATAT"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1276
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:56 GMT
last-modified:Fri, 30 Jan 2026 18:34:56 GMT
pragma:no-cache
server:nginx
x-request-id:253-23575092

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000023.10:g.123227930_123227931insGTGACTATTAATAT"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000023.10:g.123227930_123227931insGTGACTATTAATAT"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000023.10:g.123227930_123227931insGTGACTATTAATAT (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000023.10:g.123227930_123227931insGTGACTATTAATAT\"\r\n16 16   : 16ms : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n16 0    : 16ms : check code in (http://varnomen.hgvs.org) at Coding\r\n78 62   : 78ms : Code \"NC_000023.10:g.123227930_123227931insGTGACTATTAATAT\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#703

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_001184.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:34:57 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:3332c599-a9c2-4759-b3ac-5d64eeb8eaa5
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:3332c599-a9c2-4759-b3ac-5d64eeb8eaa5
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NM_001184.4"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#704

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_001184.4:c.2878_2879insAGTAA"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:864
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:57 GMT
last-modified:Fri, 30 Jan 2026 18:34:57 GMT
pragma:no-cache
server:nginx
x-request-id:253-23575108

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_001184.4:c.2878_2879insAGTAA"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_001184.4:c.2878_2879insAGTAA"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_001184.4:c.2878_2879insAGTAA (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_001184.4:c.2878_2879insAGTAA\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#705

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:882","display":"ATR"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:34:57 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:c936965f-d69a-4483-9d6d-7e54fa8d7abb
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:c936965f-d69a-4483-9d6d-7e54fa8d7abb
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:882"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#706

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA21256-5","display":"Chromosome 3"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:910
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:59 GMT
last-modified:Fri, 30 Jan 2026 18:34:59 GMT
pragma:no-cache
server:nginx
x-request-id:253-23575124

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA21256-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Chromosome 3"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA21256-5","display" : "Chromosome 3"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA21256-5 (\"Chromosome 3\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA21256-5\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#707

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000003.11"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:34:59 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:cdc743d6-67e6-4bb2-994c-1b0d7f24365c
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:cdc743d6-67e6-4bb2-994c-1b0d7f24365c
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000003.11"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#708

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000003.11:g.142269071_142269072insTTACT"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:908
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:34:59 GMT
last-modified:Fri, 30 Jan 2026 18:34:59 GMT
pragma:no-cache
server:nginx
x-request-id:253-23575163

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000003.11:g.142269071_142269072insTTACT"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000003.11:g.142269071_142269072insTTACT"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000003.11:g.142269071_142269072insTTACT (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000003.11:g.142269071_142269072insTTACT\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#709

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_001184.4:c.2878_2879insAGTAA"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1176
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:35:00 GMT
last-modified:Fri, 30 Jan 2026 18:35:00 GMT
pragma:no-cache
server:nginx
x-request-id:253-23575170

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_001184.4:c.2878_2879insAGTAA"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_001184.4:c.2878_2879insAGTAA"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_001184.4:c.2878_2879insAGTAA (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_001184.4:c.2878_2879insAGTAA\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n78 78   : 78ms : Code \"NM_001184.4:c.2878_2879insAGTAA\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#710

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:882","display":"ATR"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:35:00 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:de8abad9-bd74-45af-a317-a7829f1a46eb
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:de8abad9-bd74-45af-a317-a7829f1a46eb
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:882"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#711

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:882"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:35:01 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:0f33ac40-2344-4439-9017-fe63bd7f08d4
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:0f33ac40-2344-4439-9017-fe63bd7f08d4
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:882"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}]}

#712

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA21256-5","display":"Chromosome 3"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL2938-0","name":"LOINCAnswersLL2938-0","title":"LOINC Answer Codes for LL2938-0","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL2938-0"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1193
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:35:03 GMT
last-modified:Fri, 30 Jan 2026 18:35:03 GMT
pragma:no-cache
server:nginx
x-request-id:253-23575194

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA21256-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Chromosome 3"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA21256-5","display" : "Chromosome 3"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL2938-0 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL2938-0)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA21256-5 (\"Chromosome 3\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA21256-5\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL2938-0) at CodeableConcept.coding[0]\r\n2016 2016: 2016ms : Filter \"LIST=LL2938-0\": Code \"LA21256-5\" found in http://loinc.org|2.81\r\n"}]}

#713

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000003.11:g.142269071_142269072insTTACT"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1231
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:35:03 GMT
last-modified:Fri, 30 Jan 2026 18:35:03 GMT
pragma:no-cache
server:nginx
x-request-id:253-23575235

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000003.11:g.142269071_142269072insTTACT"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000003.11:g.142269071_142269072insTTACT"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000003.11:g.142269071_142269072insTTACT (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000003.11:g.142269071_142269072insTTACT\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n62 62   : 62ms : Code \"NC_000003.11:g.142269071_142269072insTTACT\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#714

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_005219.2:p.Leu858Arg"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:832
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:35:03 GMT
last-modified:Fri, 30 Jan 2026 18:35:03 GMT
pragma:no-cache
server:nginx
x-request-id:253-23575236

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_005219.2:p.Leu858Arg"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_005219.2:p.Leu858Arg"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_005219.2:p.Leu858Arg (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_005219.2:p.Leu858Arg\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#715

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_005228.4:c.2573T>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:824
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:35:03 GMT
last-modified:Fri, 30 Jan 2026 18:35:03 GMT
pragma:no-cache
server:nginx
x-request-id:253-23575240

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_005228.4:c.2573T>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_005228.4:c.2573T>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_005228.4:c.2573T>G (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_005228.4:c.2573T>G\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#716

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:3236","display":"EGFR"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:35:04 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:86f94d45-e796-417e-a4f0-a9a0c42582df
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:86f94d45-e796-417e-a4f0-a9a0c42582df
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:3236"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#717

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000007.13:g.55259515T>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:844
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:35:04 GMT
last-modified:Fri, 30 Jan 2026 18:35:04 GMT
pragma:no-cache
server:nginx
x-request-id:253-23575255

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000007.13:g.55259515T>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000007.13:g.55259515T>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000007.13:g.55259515T>G (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000007.13:g.55259515T>G\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#718

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_005219.2:p.Leu858Arg"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1136
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:35:04 GMT
last-modified:Fri, 30 Jan 2026 18:35:04 GMT
pragma:no-cache
server:nginx
x-request-id:253-23575261

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_005219.2:p.Leu858Arg"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_005219.2:p.Leu858Arg"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_005219.2:p.Leu858Arg (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_005219.2:p.Leu858Arg\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n79 79   : 79ms : Code \"NP_005219.2:p.Leu858Arg\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#719

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_005228.4:c.2573T>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1126
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:35:04 GMT
last-modified:Fri, 30 Jan 2026 18:35:04 GMT
pragma:no-cache
server:nginx
x-request-id:253-23575265

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_005228.4:c.2573T>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_005228.4:c.2573T>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_005228.4:c.2573T>G (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_005228.4:c.2573T>G\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n62 62   : 62ms : Code \"NM_005228.4:c.2573T>G\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#720

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:3236","display":"EGFR"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:35:05 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:64058abb-4e2f-48e5-8280-785d038613eb
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:64058abb-4e2f-48e5-8280-785d038613eb
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:3236"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#721

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:3236"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:35:05 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:eba6f806-b39d-41ce-ac83-c6202ce78b99
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:eba6f806-b39d-41ce-ac83-c6202ce78b99
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:3236"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}]}

#722

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000007.13:g.55259515T>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1151
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:35:06 GMT
last-modified:Fri, 30 Jan 2026 18:35:06 GMT
pragma:no-cache
server:nginx
x-request-id:253-23575289

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000007.13:g.55259515T>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000007.13:g.55259515T>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000007.13:g.55259515T>G (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000007.13:g.55259515T>G\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n78 78   : 78ms : Code \"NC_000007.13:g.55259515T>G\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#723

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:10261","display":"ROS1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:35:06 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:ab340aaa-981b-45dc-a377-b34c58d6b0a6
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:ab340aaa-981b-45dc-a377-b34c58d6b0a6
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:10261"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#724

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:10261","display":"ROS1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:35:07 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:1c2c1eaa-688a-4dd6-9f03-1f1756d0e4f8
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:1c2c1eaa-688a-4dd6-9f03-1f1756d0e4f8
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:10261"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#725

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:10261"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:35:07 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:3fa6f602-af57-4e17-b7ae-74941f47bf3c
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:3fa6f602-af57-4e17-b7ae-74941f47bf3c
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:10261"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}]}

#726

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26333-7","display":"Uncertain Significance"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:940
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:35:09 GMT
last-modified:Fri, 30 Jan 2026 18:35:09 GMT
pragma:no-cache
server:nginx
x-request-id:253-23575324

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26333-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Uncertain significance"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26333-7","display" : "Uncertain Significance"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA26333-7 (\"Uncertain Significance\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA26333-7\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#727

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81259-4","display":"Associated phenotype"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:926
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:35:10 GMT
last-modified:Fri, 30 Jan 2026 18:35:10 GMT
pragma:no-cache
server:nginx
x-request-id:253-23575353

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81259-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Associated phenotype"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81259-4","display" : "Associated phenotype"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81259-4 (\"Associated phenotype\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81259-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#728

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"699346009","display":"Hereditary cancer-predisposing syndrome (disorder)"}],"text":"Hereditary cancer-predisposing syndrome"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1193
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:35:10 GMT
last-modified:Fri, 30 Jan 2026 18:35:10 GMT
pragma:no-cache
server:nginx
x-request-id:253-23575384

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "699346009"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Hereditary neoplastic syndrome"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "699346009","display" : "Hereditary cancer-predisposing syndrome (disorder)"}],"text" : "Hereditary cancer-predisposing syndrome"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://snomed.info/sct#699346009 (\"Hereditary cancer-predisposing syndrome (disorder)\")]\"\r\n0 0     : 0ms  : Check \"http://snomed.info/sct#699346009\"\r\n0 0     : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#729

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26332-9","display":"Likely Pathogenic"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:925
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:35:12 GMT
last-modified:Fri, 30 Jan 2026 18:35:12 GMT
pragma:no-cache
server:nginx
x-request-id:253-23575389

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26332-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Likely pathogenic"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26332-9","display" : "Likely Pathogenic"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA26332-9 (\"Likely Pathogenic\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA26332-9\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#730

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"93044-6","display":"Level of evidence"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:917
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:35:14 GMT
last-modified:Fri, 30 Jan 2026 18:35:14 GMT
pragma:no-cache
server:nginx
x-request-id:253-23575417

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "93044-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Level of evidence"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "93044-6","display" : "Level of evidence"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#93044-6 (\"Level of evidence\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#93044-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#731

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"254637007","display":"Non-small cell lung cancer (disorder)"}],"text":"Non-small cell lung cancer"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1150
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:35:14 GMT
last-modified:Fri, 30 Jan 2026 18:35:14 GMT
pragma:no-cache
server:nginx
x-request-id:253-23575445

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "254637007"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Non-small cell lung cancer"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "254637007","display" : "Non-small cell lung cancer (disorder)"}],"text" : "Non-small cell lung cancer"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://snomed.info/sct#254637007 (\"Non-small cell lung cancer (disorder)\")]\"\r\n0 0     : 0ms  : Check \"http://snomed.info/sct#254637007\"\r\n0 0     : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#732

GET https://tx-nordics.fhir.org/fhir/r4/CodeSystem?_format=json&url=http%3A%2F%2Fclinicaltrials.gov HTTP/1.0
User-Agent: hapi-fhir-tooling-client
Accept: application/fhir+json; fhirVersion=4.0

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:35:14 GMT
etag:W/"1767473543112"
last-modified:Fri, 30 Jan 2026 18:35:14 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:fb53a6e7-4dcd-460c-892e-27df80b11783
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:fb53a6e7-4dcd-460c-892e-27df80b11783
x-xss-protection:0

{"resourceType":"Bundle","id":"801e7e24-1f47-3306-bc0b-4ad0beceb82c","meta":{"lastUpdated":"2026-01-30T19:35:14.710+01:00","tag":[{"system":"http://terminology.hl7.org/CodeSystem/v3-ObservationValue","code":"SUBSETTED","display":"Resource encoded in summary mode"}]},"type":"searchset","total":1,"link":[{"relation":"self","url":"https://tx-nordics.fhir.org/fhir/r4/CodeSystem?_format=json&_summary=true&url=http%3A%2F%2Fclinicaltrials.gov"}],"entry":[{"fullUrl":"https://tx-nordics.fhir.org/fhir/r4/CodeSystem/beb642d1-baff-4748-900d-d1b1872e345c","resource":{"resourceType":"CodeSystem","id":"beb642d1-baff-4748-900d-d1b1872e345c","meta":{"versionId":"1","lastUpdated":"2025-10-26T18:16:30.455+01:00","tag":[{"system":"http://terminology.hl7.org/CodeSystem/v3-ObservationValue","code":"SUBSETTED","display":"Resource encoded in summary mode"}]},"url":"http://clinicaltrials.gov","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.3.1077"}],"version":"1.0.0","name":"ClinicalTrialsGov","title":"ClinicalTrials.gov","status":"active","experimental":false,"date":"2024-04-24T00:00:00-00:00","publisher":"National Library of Medicine","contact":[{"name":"National Library of Medicine; 8600 Rockville Pike, Bethesda, MD 20894","telecom":[{"system":"url","value":"https://www.nlm.nih.gov/"},{"system":"url","value":"https://support.nlm.nih.gov/support/create-case/"}]}],"caseSensitive":true,"content":"not-present"}}]}

#733

GET https://tx-nordics.fhir.org/fhir/r4/CodeSystem/beb642d1-baff-4748-900d-d1b1872e345c HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
User-Agent: fhir/publisher

200
cache-control:no-cache
content-location:https://tx-nordics.fhir.org/fhir/r4/CodeSystem/beb642d1-baff-4748-900d-d1b1872e345c/_history/1
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:35:15 GMT
etag:W/"1"
last-modified:Sun, 26 Oct 2025 17:16:30 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:a0658dab-b12b-4fd2-84da-74d5aeeed237
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:a0658dab-b12b-4fd2-84da-74d5aeeed237
x-xss-protection:0

{"resourceType":"CodeSystem","id":"beb642d1-baff-4748-900d-d1b1872e345c","meta":{"versionId":"1","lastUpdated":"2025-10-26T18:16:30.455+01:00"},"text":{"status":"generated","div":"<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: CodeSystem ClinicalTrialsGov</b></p><a name=\"ClinicalTrialsGov\"/><a name=\"hcClinicalTrialsGov\"/><p>This case-sensitive code system <code>http://clinicaltrials.gov</code> defines codes, but no codes are represented here</p></div>"},"url":"http://clinicaltrials.gov","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.3.1077"}],"version":"1.0.0","name":"ClinicalTrialsGov","title":"ClinicalTrials.gov","status":"active","experimental":false,"date":"2024-04-24T00:00:00-00:00","publisher":"National Library of Medicine","contact":[{"name":"National Library of Medicine; 8600 Rockville Pike, Bethesda, MD 20894","telecom":[{"system":"url","value":"https://www.nlm.nih.gov/"},{"system":"url","value":"https://support.nlm.nih.gov/support/create-case/"}]}],"description":"The U.S. National Institutes of Health, Department of Health and Human Services, through its National Library of Medicine, has developed [ClinicalTrials.gov](http://clinicaltrials.gov) to provide patients, family members, and members of the public current information about clinical research studies. [ClinicalTrials.gov](http://clinicaltrials.gov) contains summary information about clinical studies being conducted throughout the United States and in many countries throughout the world. These data are provided to the National Library of Medicine by organizations and institutions that sponsor and implement the studies.\r\n\r\n[ClinicalTrials.gov](http://clinicaltrials.gov) is updated daily. You should check [ClinicalTrials.gov](http://clinicaltrials.gov) frequently for updated information.\r\n\r\nMore information about ClinicalTrials.gov can be found [here](https://clinicaltrials.gov/about-site/about-ctg).","copyright":"See [https://clinicaltrials.gov/about-site/terms-conditions](https://clinicaltrials.gov/about-site/terms-conditions) for the Terms and Conditions that apply for use of ClinicalTrials.gov data.","caseSensitive":true,"content":"not-present"}

#734

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://clinicaltrials.gov","code":"NCT04919811","display":"NCT04919811"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NCT04919811"},{"name":"system","valueUri":"http://clinicaltrials.gov"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://clinicaltrials.gov was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://clinicaltrials.gov' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://clinicaltrials.gov"},{"name":"message","valueString":"A definition for CodeSystem 'http://clinicaltrials.gov' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://clinicaltrials.gov was not found"}]}

#735

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6677-4","display":"Responsive"}],"text":"cancer sensitive to crizotinib"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6677-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Responsive"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6677-4","display" : "Responsive"}],"text" : "cancer sensitive to crizotinib"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA6677-4 (\"Responsive\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA6677-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#736

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
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{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6677-4","display":"Responsive"}],"text":"cancer sensitive to crizotinib"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"genetic-therapeutic-implications-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs","version":"4.0.0-cibuild","name":"GeneticTherapeuticImplicationsVS","title":"Genetic Therapeutic Implications","status":"active","experimental":false,"date":"2026-01-30T18:21:39+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for terms that describe a predicted ramification based on the presence of associated molecular finding(s).","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This material contains content from LOINC (http://loinc.org). LOINC is copyright © 1995-2020, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC® is a registered United States trademark of Regenstrief Institute, Inc.\nThis value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement.","compose":{"include":[{"system":"http://loinc.org","concept":[{"code":"LA10315-2","display":"Ultrarapid metabolizer"},{"code":"LA25391-6","display":"Normal metabolizer"},{"code":"LA25390-8","display":"Rapid metabolizer"},{"code":"LA10317-8","display":"Intermediate metabolizer"},{"code":"LA9657-3","display":"Poor metabolizer"},{"code":"LA19542-2","display":"Low Risk"},{"code":"LA19541-4","display":"High Risk"},{"code":"LA6676-6","display":"Resistant"},{"code":"LA6677-4","display":"Responsive"},{"code":"LA9660-7","display":"Presumed resistant"},{"code":"LA9661-5","display":"Presumed responsive"},{"code":"LA6682-4","display":"Unknown Significance"},{"code":"LA6675-8","display":"Benign"},{"code":"LA6674-1","display":"Presumed Benign"},{"code":"LA9662-3","display":"Presumed non-responsive"},{"code":"LA25392-4","display":"Increased function"},{"code":"LA25393-2","display":"Normal function"},{"code":"LA25395-7","display":"Decreased function"},{"code":"LA25394-0","display":"Poor function"}]},{"system":"http://snomed.info/sct","concept":[{"code":"444734003","display":"Does not meet eligibility criteria for clinical trial (finding)"},{"code":"399223003","display":"Patient eligible for clinical trial (finding)"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
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date:Fri, 30 Jan 2026 18:35:17 GMT
last-modified:Fri, 30 Jan 2026 18:35:17 GMT
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6677-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Responsive"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6677-4","display" : "Responsive"}],"text" : "cancer sensitive to crizotinib"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15   : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-cibuild for validation purposes\r\n15 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n15 0    : 0ms  : Prepare include: \"(http://loinc.org)(LA10315-2,LA25391-6,LA25390-8,LA10317-8,LA9657-3,LA19542-2,LA19541-4,LA6676-6,LA6677-4,LA9660-7,LA9661-5,LA6682-4,LA6675-8,LA6674-1,LA9662-3,LA25392-4,LA25393-2,LA25395-7,LA25394-0)\"\r\n15 0    : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n15 0    : 0ms  : Prepare include: \"(http://snomed.info/sct)(444734003,399223003)\"\r\n15 0    : 0ms  : CodeSystem found: \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\"\r\n15 0    : 0ms  : Validate \"[http://loinc.org#LA6677-4 (\"Responsive\")]\"\r\n15 0    : 0ms  : Check \"http://loinc.org#LA6677-4\"\r\n31 16   : 16ms : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n31 0    : 16ms : check code in (http://loinc.org)(LA10315-2,LA25391-6,LA25390-8,LA10317-8,LA9657-3,LA19542-2,LA19541-4,LA6676-6,LA6677-4,LA9660-7,LA9661-5,LA6682-4,LA6675-8,LA6674-1,LA9662-3,LA25392-4,LA25393-2,LA25395-7,LA25394-0) at CodeableConcept.coding[0]\r\n31 0    : 16ms : Code \"LA6677-4\" found in http://loinc.org|2.81\r\n"}]}

#737

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6677-4","display":"Responsive"}],"text":"cancer sensitive to pembrolizumab"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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connection:keep-alive
content-length:945
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:35:19 GMT
last-modified:Fri, 30 Jan 2026 18:35:19 GMT
pragma:no-cache
server:nginx
x-request-id:253-23575514

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6677-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Responsive"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6677-4","display" : "Responsive"}],"text" : "cancer sensitive to pembrolizumab"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA6677-4 (\"Responsive\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA6677-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#738

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6677-4","display":"Responsive"}],"text":"cancer sensitive to pembrolizumab"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"genetic-therapeutic-implications-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs","version":"4.0.0-cibuild","name":"GeneticTherapeuticImplicationsVS","title":"Genetic Therapeutic Implications","status":"active","experimental":false,"date":"2026-01-30T18:21:39+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for terms that describe a predicted ramification based on the presence of associated molecular finding(s).","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This material contains content from LOINC (http://loinc.org). LOINC is copyright © 1995-2020, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC® is a registered United States trademark of Regenstrief Institute, Inc.\nThis value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement.","compose":{"include":[{"system":"http://loinc.org","concept":[{"code":"LA10315-2","display":"Ultrarapid metabolizer"},{"code":"LA25391-6","display":"Normal metabolizer"},{"code":"LA25390-8","display":"Rapid metabolizer"},{"code":"LA10317-8","display":"Intermediate metabolizer"},{"code":"LA9657-3","display":"Poor metabolizer"},{"code":"LA19542-2","display":"Low Risk"},{"code":"LA19541-4","display":"High Risk"},{"code":"LA6676-6","display":"Resistant"},{"code":"LA6677-4","display":"Responsive"},{"code":"LA9660-7","display":"Presumed resistant"},{"code":"LA9661-5","display":"Presumed responsive"},{"code":"LA6682-4","display":"Unknown Significance"},{"code":"LA6675-8","display":"Benign"},{"code":"LA6674-1","display":"Presumed Benign"},{"code":"LA9662-3","display":"Presumed non-responsive"},{"code":"LA25392-4","display":"Increased function"},{"code":"LA25393-2","display":"Normal function"},{"code":"LA25395-7","display":"Decreased function"},{"code":"LA25394-0","display":"Poor function"}]},{"system":"http://snomed.info/sct","concept":[{"code":"444734003","display":"Does not meet eligibility criteria for clinical trial (finding)"},{"code":"399223003","display":"Patient eligible for clinical trial (finding)"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1815
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:35:19 GMT
last-modified:Fri, 30 Jan 2026 18:35:19 GMT
pragma:no-cache
server:nginx
x-request-id:253-23575541

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6677-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Responsive"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6677-4","display" : "Responsive"}],"text" : "cancer sensitive to pembrolizumab"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15   : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-cibuild for validation purposes\r\n15 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n15 0    : 0ms  : Prepare include: \"(http://loinc.org)(LA10315-2,LA25391-6,LA25390-8,LA10317-8,LA9657-3,LA19542-2,LA19541-4,LA6676-6,LA6677-4,LA9660-7,LA9661-5,LA6682-4,LA6675-8,LA6674-1,LA9662-3,LA25392-4,LA25393-2,LA25395-7,LA25394-0)\"\r\n15 0    : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n15 0    : 0ms  : Prepare include: \"(http://snomed.info/sct)(444734003,399223003)\"\r\n15 0    : 0ms  : CodeSystem found: \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\"\r\n15 0    : 0ms  : Validate \"[http://loinc.org#LA6677-4 (\"Responsive\")]\"\r\n15 0    : 0ms  : Check \"http://loinc.org#LA6677-4\"\r\n15 0    : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n15 0    : 0ms  : check code in (http://loinc.org)(LA10315-2,LA25391-6,LA25390-8,LA10317-8,LA9657-3,LA19542-2,LA19541-4,LA6676-6,LA6677-4,LA9660-7,LA9661-5,LA6682-4,LA6675-8,LA6674-1,LA9662-3,LA25392-4,LA25393-2,LA25395-7,LA25394-0) at CodeableConcept.coding[0]\r\n15 0    : 0ms  : Code \"LA6677-4\" found in http://loinc.org|2.81\r\n"}]}

#739

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48004-6"}],"text":"coding HGVS"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:893
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:35:20 GMT
last-modified:Fri, 30 Jan 2026 18:35:20 GMT
pragma:no-cache
server:nginx
x-request-id:253-23575546

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48004-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "DNA change (c.HGVS)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48004-6"}],"text" : "coding HGVS"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48004-6 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48004-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#740

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_017617.5:c.5791G>A","display":"NM_017617.5:c.5791G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:845
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:35:21 GMT
last-modified:Fri, 30 Jan 2026 18:35:21 GMT
pragma:no-cache
server:nginx
x-request-id:253-23575570

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_017617.5:c.5791G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_017617.5:c.5791G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_017617.5:c.5791G>A (\"NM_017617.5:c.5791G>A\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_017617.5:c.5791G>A\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#741

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_017617.5","display":"NM_017617.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:35:21 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:a2bfa9f1-8bb9-4691-be3f-ce542e1ef4c4
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:a2bfa9f1-8bb9-4691-be3f-ce542e1ef4c4
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NM_017617.5"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#742

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001583","display":"missense_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:35:22 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:8f6479e0-5c97-4602-9c33-ff31900562b1
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:8f6479e0-5c97-4602-9c33-ff31900562b1
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001583"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#743

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_060087.3:p.A1931T","display":"NP_060087.3:p.A1931T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:840
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:35:22 GMT
last-modified:Fri, 30 Jan 2026 18:35:22 GMT
pragma:no-cache
server:nginx
x-request-id:253-23575590

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_060087.3:p.A1931T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_060087.3:p.A1931T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_060087.3:p.A1931T (\"NP_060087.3:p.A1931T\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_060087.3:p.A1931T\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#744

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001583","display":"missense_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:35:22 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:4c66cf39-0ef0-40a1-b420-e57e33d678de
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:4c66cf39-0ef0-40a1-b420-e57e33d678de
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001583"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#745

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001583"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0001537"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:35:23 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:a2a249c0-f221-4a94-9496-00c4584457c7
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:a2a249c0-f221-4a94-9496-00c4584457c7
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001583"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}]}

#746

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_006885.4:c.1753G>A","display":"NM_006885.4:c.1753G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:845
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:35:23 GMT
last-modified:Fri, 30 Jan 2026 18:35:23 GMT
pragma:no-cache
server:nginx
x-request-id:253-23575612

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_006885.4:c.1753G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_006885.4:c.1753G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_006885.4:c.1753G>A (\"NM_006885.4:c.1753G>A\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_006885.4:c.1753G>A\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#747

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_006885.4","display":"NM_006885.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:35:23 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:35515b1a-90f5-4517-8791-7ad5e5617d05
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:35515b1a-90f5-4517-8791-7ad5e5617d05
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NM_006885.4"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#748

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_008816.3:p.G585S","display":"NP_008816.3:p.G585S"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:835
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:35:24 GMT
last-modified:Fri, 30 Jan 2026 18:35:24 GMT
pragma:no-cache
server:nginx
x-request-id:253-23575628

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_008816.3:p.G585S"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_008816.3:p.G585S"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_008816.3:p.G585S (\"NP_008816.3:p.G585S\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_008816.3:p.G585S\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#749

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000251.3:c.1832del","display":"NM_000251.3:c.1832del"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:845
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:35:24 GMT
last-modified:Fri, 30 Jan 2026 18:35:24 GMT
pragma:no-cache
server:nginx
x-request-id:253-23575630

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000251.3:c.1832del"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000251.3:c.1832del"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_000251.3:c.1832del (\"NM_000251.3:c.1832del\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_000251.3:c.1832del\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#750

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001589","display":"frameshift_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:35:24 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:a2060dc3-38f1-49a7-8f14-623156870015
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:a2060dc3-38f1-49a7-8f14-623156870015
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001589"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#751

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000251.3:c.1832del"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1126
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:35:25 GMT
last-modified:Fri, 30 Jan 2026 18:35:25 GMT
pragma:no-cache
server:nginx
x-request-id:253-23575644

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000251.3:c.1832del"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000251.3:c.1832del"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_000251.3:c.1832del (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_000251.3:c.1832del\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n78 78   : 78ms : Code \"NM_000251.3:c.1832del\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#752

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001589","display":"frameshift_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:35:25 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:ec5f01f4-78ab-40df-b8a1-913c3bdf3d10
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:ec5f01f4-78ab-40df-b8a1-913c3bdf3d10
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001589"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#753

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001589"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0001537"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:35:26 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:8dd3df0e-d643-4fe8-989d-a09cbcb4124f
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:8dd3df0e-d643-4fe8-989d-a09cbcb4124f
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001589"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}]}

#754

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_002528.7:c.728G>A","display":"NM_002528.7:c.728G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:840
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:35:26 GMT
last-modified:Fri, 30 Jan 2026 18:35:26 GMT
pragma:no-cache
server:nginx
x-request-id:253-23575667

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_002528.7:c.728G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_002528.7:c.728G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_002528.7:c.728G>A (\"NM_002528.7:c.728G>A\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_002528.7:c.728G>A\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#755

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001587","display":"stop_gained"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:35:26 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:063a087f-a60f-45a1-bdc6-9c60156d099f
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:063a087f-a60f-45a1-bdc6-9c60156d099f
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001587"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#756

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_002519.2:p.Trp243Ter","display":"NP_002519.2:p.Trp243Ter"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:855
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:35:26 GMT
last-modified:Fri, 30 Jan 2026 18:35:26 GMT
pragma:no-cache
server:nginx
x-request-id:253-23575685

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_002519.2:p.Trp243Ter"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_002519.2:p.Trp243Ter"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_002519.2:p.Trp243Ter (\"NP_002519.2:p.Trp243Ter\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_002519.2:p.Trp243Ter\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#757

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001587","display":"stop_gained"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:35:27 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:499b877e-c7d0-47f1-93e8-bc3f7f585069
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:499b877e-c7d0-47f1-93e8-bc3f7f585069
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001587"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#758

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001587"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0001537"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:35:27 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:598f8a4d-2b5b-413e-b704-968c92424829
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:598f8a4d-2b5b-413e-b704-968c92424829
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001587"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}]}

#759

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_006603.5:c.3530_3531insGTGACTATTAATAT","display":"NM_006603.5:c.3530_3531insGTGACTATTAATAT"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:940
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:35:28 GMT
last-modified:Fri, 30 Jan 2026 18:35:28 GMT
pragma:no-cache
server:nginx
x-request-id:253-23575710

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_006603.5:c.3530_3531insGTGACTATTAATAT"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_006603.5:c.3530_3531insGTGACTATTAATAT"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_006603.5:c.3530_3531insGTGACTATTAATAT (\"NM_006603.5:c.3530_3531insGTGACTATTAATAT\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_006603.5:c.3530_3531insGTGACTATTAATAT\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#760

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_006603.5","display":"NM_006603.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:35:28 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:bbab91b0-ae85-456c-8378-3c04a3a77206
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:bbab91b0-ae85-456c-8378-3c04a3a77206
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NM_006603.5"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#761

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_006594.3:p.S1178*","display":"NP_006594.3:p.S1178*"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:840
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:35:28 GMT
last-modified:Fri, 30 Jan 2026 18:35:28 GMT
pragma:no-cache
server:nginx
x-request-id:253-23575724

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_006594.3:p.S1178*"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_006594.3:p.S1178*"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_006594.3:p.S1178* (\"NP_006594.3:p.S1178*\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_006594.3:p.S1178*\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#762

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_001184.4:c.2878_2879insAGTAA","display":"NM_001184.4:c.2878_2879insAGTAA"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:895
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:35:29 GMT
last-modified:Fri, 30 Jan 2026 18:35:29 GMT
pragma:no-cache
server:nginx
x-request-id:253-23575728

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_001184.4:c.2878_2879insAGTAA"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_001184.4:c.2878_2879insAGTAA"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_001184.4:c.2878_2879insAGTAA (\"NM_001184.4:c.2878_2879insAGTAA\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_001184.4:c.2878_2879insAGTAA\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#763

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_001184.4","display":"NM_001184.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:35:29 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:2ad25051-e98a-4929-aec1-30a9f1a957e0
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:2ad25051-e98a-4929-aec1-30a9f1a957e0
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NM_001184.4"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#764

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO_0002054","display":"loss_of_function_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:35:30 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:7c1a9cfd-bf4b-4633-a6f6-86921bcdb827
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:7c1a9cfd-bf4b-4633-a6f6-86921bcdb827
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO_0002054"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#765

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO_0002054","display":"loss_of_function_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:35:30 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:c11c0908-b897-41d5-a0a2-9c5a1e775937
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:c11c0908-b897-41d5-a0a2-9c5a1e775937
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO_0002054"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#766

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO_0002054"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/functional-effect-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0001536"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:35:31 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:feeb728b-2012-45db-95c4-7e6d2e8ad051
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:feeb728b-2012-45db-95c4-7e6d2e8ad051
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO_0002054"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/functional-effect-vs--0|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/functional-effect-vs--0|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}]}

#767

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_005228.4:c.2573T>G","display":"NM_005228.4:c.2573T>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:845
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:35:31 GMT
last-modified:Fri, 30 Jan 2026 18:35:31 GMT
pragma:no-cache
server:nginx
x-request-id:253-23575765

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_005228.4:c.2573T>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_005228.4:c.2573T>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_005228.4:c.2573T>G (\"NM_005228.4:c.2573T>G\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_005228.4:c.2573T>G\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#768

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_005219.2:p.Leu858Arg","display":"NP_005219.2:p.Leu858Arg"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:855
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:35:31 GMT
last-modified:Fri, 30 Jan 2026 18:35:31 GMT
pragma:no-cache
server:nginx
x-request-id:253-23575773

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_005219.2:p.Leu858Arg"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_005219.2:p.Leu858Arg"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_005219.2:p.Leu858Arg (\"NP_005219.2:p.Leu858Arg\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_005219.2:p.Leu858Arg\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#769

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001886","display":"transcript_fusion"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:35:31 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:28add8b8-b31e-4ee4-abd1-128160515a95
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:28add8b8-b31e-4ee4-abd1-128160515a95
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001886"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#770

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001886","display":"transcript_fusion"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:35:32 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:1d18da9e-633b-432c-a8b2-afb8df4ccdc7
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:1d18da9e-633b-432c-a8b2-afb8df4ccdc7
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001886"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#771

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001886"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/functional-effect-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0001536"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:35:33 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:6bdd6828-b06c-4f17-ba69-5f7cd7b823ab
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x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:6bdd6828-b06c-4f17-ba69-5f7cd7b823ab
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001886"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/functional-effect-vs--0|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/functional-effect-vs--0|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}]}

#772

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26203-2","display":"MSI-H"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:889
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:35:34 GMT
last-modified:Fri, 30 Jan 2026 18:35:34 GMT
pragma:no-cache
server:nginx
x-request-id:253-23575806

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26203-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "MSI-H"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26203-2","display" : "MSI-H"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA26203-2 (\"MSI-H\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA26203-2\"\r\n15 15   : 15ms : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#773

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"85147-7","display":"PD-L1 by clone 22C3 in Tissue by Immune stain Report"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1022
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:35:36 GMT
last-modified:Fri, 30 Jan 2026 18:35:36 GMT
pragma:no-cache
server:nginx
x-request-id:253-23575834

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "85147-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "PD-L1 by clone 22C3 in Tissue by Immune stain Report"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "85147-7","display" : "PD-L1 by clone 22C3 in Tissue by Immune stain Report"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#85147-7 (\"PD-L1 by clone 22C3 in Tissue by Immune stain Report\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#85147-7\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#774

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:17635","display":"CD274"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:35:36 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:498fcec0-67cb-4e51-b1fd-257e88c7d264
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:498fcec0-67cb-4e51-b1fd-257e88c7d264
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:17635"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#775

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:17635","display":"CD274"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:35:37 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:ab2f6914-f6a6-4b74-ba2c-b47b296b75e8
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x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:ab2f6914-f6a6-4b74-ba2c-b47b296b75e8
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:17635"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#776

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:17635"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:35:37 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:a0aaf1c5-58b6-4054-9188-47a8e7c9ea8a
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x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:a0aaf1c5-58b6-4054-9188-47a8e7c9ea8a
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:17635"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}]}

#777

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26203-2","display":"MSI-H"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL1971-2","name":"LOINCAnswersLL1971-2","title":"LOINC Answer Codes for LL1971-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL1971-2"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2193
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:35:40 GMT
last-modified:Fri, 30 Jan 2026 18:35:40 GMT
pragma:no-cache
server:nginx
x-request-id:253-23575903

{"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1971-2'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26203-2","display" : "MSI-H"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA26203-2 ('MSI-H')' was not found in the value set 'http://loinc.org/vs/LL1971-2'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1971-2'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL1971-2 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL1971-2)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA26203-2 (\"MSI-H\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA26203-2\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL1971-2) at CodeableConcept.coding[0]\r\n1297 1297: 1297ms : Filter \"LIST=LL1971-2\": Code \"LA26203-2\" not found in http://loinc.org|2.81\r\n"}]}

#778

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

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{"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1971-2'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6576-8","display" : "Positive"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA6576-8 ('Positive')' was not found in the value set 'http://loinc.org/vs/LL1971-2'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1971-2'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL1971-2 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL1971-2)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA6576-8 (\"Positive\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA6576-8\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL1971-2) at CodeableConcept.coding[0]\r\n375 375 : 375ms : Filter \"LIST=LL1971-2\": Code \"LA6576-8\" not found in http://loinc.org|2.81\r\n"}]}

#779

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
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{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26203-2","display":"MSI-H"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"sequence-phase-relationship-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs","version":"4.0.0-cibuild","name":"SequencePhaseRelationshipVS","title":"Sequence Phase Relationships","status":"active","experimental":false,"date":"2026-01-30T18:21:39+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for specific types of relationships","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"compose":{"include":[{"system":"http://terminology.hl7.org/CodeSystem/sequence-phase-relationship-cs"}]}}},{"name":"tx-resource","resource":{"resourceType":"CodeSystem","id":"sequence-phase-relationship-cs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://terminology.hl7.org/CodeSystem/sequence-phase-relationship-cs","version":"4.0.0-cibuild","name":"SequencePhaseRelationshipCS","title":"Sequence Phase Relationship Codes","status":"active","experimental":false,"date":"2026-01-30T18:21:39+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Code System for specific types of relationships","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"caseSensitive":true,"content":"complete","count":4,"concept":[{"code":"Cis","display":"Cis","definition":"Phase is in cis (same chromosome)"},{"code":"Trans","display":"Trans","definition":"Phase is in trans (different chromosomes)"},{"code":"Indeterminate","display":"Indeterminate","definition":"Phase is unable to be determined"},{"code":"Unknown","display":"Unknown","definition":"Phase is unknown"}]}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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date:Fri, 30 Jan 2026 18:35:41 GMT
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{"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-cibuild'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26203-2","display" : "MSI-H"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA26203-2 ('MSI-H')' was not found in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-cibuild'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-cibuild'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n32 32   : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-cibuild for validation purposes\r\n32 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n32 0    : 0ms  : Prepare include: \"(http://terminology.hl7.org/CodeSystem/sequence-phase-relationship-cs)\"\r\n32 0    : 0ms  : CodeSystem found: \"http://terminology.hl7.org/CodeSystem/sequence-phase-relationship-cs|4.0.0-cibuild\"\r\n32 0    : 0ms  : Validate \"[http://loinc.org#LA26203-2 (\"MSI-H\")]\"\r\n32 0    : 0ms  : Check \"http://loinc.org#LA26203-2\"\r\n"}]}

#780

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6576-8","display":"Positive"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"sequence-phase-relationship-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs","version":"4.0.0-cibuild","name":"SequencePhaseRelationshipVS","title":"Sequence Phase Relationships","status":"active","experimental":false,"date":"2026-01-30T18:21:39+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for specific types of relationships","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"compose":{"include":[{"system":"http://terminology.hl7.org/CodeSystem/sequence-phase-relationship-cs"}]}}},{"name":"tx-resource","resource":{"resourceType":"CodeSystem","id":"sequence-phase-relationship-cs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://terminology.hl7.org/CodeSystem/sequence-phase-relationship-cs","version":"4.0.0-cibuild","name":"SequencePhaseRelationshipCS","title":"Sequence Phase Relationship Codes","status":"active","experimental":false,"date":"2026-01-30T18:21:39+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Code System for specific types of relationships","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"caseSensitive":true,"content":"complete","count":4,"concept":[{"code":"Cis","display":"Cis","definition":"Phase is in cis (same chromosome)"},{"code":"Trans","display":"Trans","definition":"Phase is in trans (different chromosomes)"},{"code":"Indeterminate","display":"Indeterminate","definition":"Phase is unable to be determined"},{"code":"Unknown","display":"Unknown","definition":"Phase is unknown"}]}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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{"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-cibuild'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6576-8","display" : "Positive"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA6576-8 ('Positive')' was not found in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-cibuild'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-cibuild'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15   : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-cibuild for validation purposes\r\n15 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n15 0    : 0ms  : Prepare include: \"(http://terminology.hl7.org/CodeSystem/sequence-phase-relationship-cs)\"\r\n15 0    : 0ms  : CodeSystem found: \"http://terminology.hl7.org/CodeSystem/sequence-phase-relationship-cs|4.0.0-cibuild\"\r\n15 0    : 0ms  : Validate \"[http://loinc.org#LA6576-8 (\"Positive\")]\"\r\n15 0    : 0ms  : Check \"http://loinc.org#LA6576-8\"\r\n"}]}

#781

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48013-7","display":"Genomic reference sequence [ID]"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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date:Fri, 30 Jan 2026 18:35:43 GMT
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48013-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic reference sequence [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48013-7","display" : "Genomic reference sequence [ID]"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48013-7 (\"Genomic reference sequence [ID]\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48013-7\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#782

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"53034-5","display":"Allelic State"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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last-modified:Fri, 30 Jan 2026 18:35:45 GMT
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "53034-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic state"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "53034-5","display" : "Allelic State"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#53034-5 (\"Allelic State\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#53034-5\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#783

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81254-5","display":"Genomic allele start-end"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
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cache-control:public, max-age=600
connection:keep-alive
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content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:35:46 GMT
last-modified:Fri, 30 Jan 2026 18:35:46 GMT
pragma:no-cache
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x-request-id:253-23576033

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81254-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic allele start-end"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81254-5","display" : "Genomic allele start-end"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81254-5 (\"Genomic allele start-end\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81254-5\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#784

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"398036000","display":"Familial hypercholesterolemia (disorder)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1132
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:35:46 GMT
last-modified:Fri, 30 Jan 2026 18:35:46 GMT
pragma:no-cache
server:nginx
x-request-id:253-23576051

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "398036000"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Familial hypercholesterolemia (disorder)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "398036000","display" : "Familial hypercholesterolemia (disorder)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://snomed.info/sct#398036000 (\"Familial hypercholesterolemia (disorder)\")]\"\r\n0 0     : 0ms  : Check \"http://snomed.info/sct#398036000\"\r\n0 0     : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#785

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001019","display":"copy_number_variation"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:35:47 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:2c7b587b-9e50-4a87-ae6c-c3e8150b366c
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:2c7b587b-9e50-4a87-ae6c-c3e8150b366c
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001019"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#786

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001019"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0002072"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:35:47 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:7a497efb-0435-4fc6-8047-ea2372dda19c
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:7a497efb-0435-4fc6-8047-ea2372dda19c
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001019"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}]}

#787

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001019","display":"copy_number_variation"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:35:48 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:ba2cb024-b728-434b-9d10-7ef045b2b957
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:ba2cb024-b728-434b-9d10-7ef045b2b957
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001019"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#788

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000022.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:35:48 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:655b03ea-9b52-4b48-b738-27cae2d55788
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:655b03ea-9b52-4b48-b738-27cae2d55788
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000022.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#789

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26320-4","display":"Maternal"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL5489-1","name":"LOINCAnswersLL5489-1","title":"LOINC Answer Codes for LL5489-1","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL5489-1"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1181
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:35:50 GMT
last-modified:Fri, 30 Jan 2026 18:35:50 GMT
pragma:no-cache
server:nginx
x-request-id:253-23576093

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26320-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Maternal"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26320-4","display" : "Maternal"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL5489-1 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL5489-1)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA26320-4 (\"Maternal\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA26320-4\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL5489-1) at CodeableConcept.coding[0]\r\n1609 1609: 1609ms : Filter \"LIST=LL5489-1\": Code \"LA26320-4\" found in http://loinc.org|2.81\r\n"}]}

#790

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26320-4","display":"Maternal"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:898
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:35:51 GMT
last-modified:Fri, 30 Jan 2026 18:35:51 GMT
pragma:no-cache
server:nginx
x-request-id:253-23576118

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26320-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Maternal"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26320-4","display" : "Maternal"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA26320-4 (\"Maternal\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA26320-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#791

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26426-9","display":"Directly measured"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL4050-2","name":"LOINCAnswersLL4050-2","title":"LOINC Answer Codes for LL4050-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL4050-2"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1208
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:35:54 GMT
last-modified:Fri, 30 Jan 2026 18:35:54 GMT
pragma:no-cache
server:nginx
x-request-id:253-23576140

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26426-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Directly measured"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26426-9","display" : "Directly measured"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL4050-2 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL4050-2)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA26426-9 (\"Directly measured\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA26426-9\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL4050-2) at CodeableConcept.coding[0]\r\n2000 2000: 2000ms : Filter \"LIST=LL4050-2\": Code \"LA26426-9\" found in http://loinc.org|2.81\r\n"}]}

#792

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26426-9","display":"Directly measured"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:925
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:35:55 GMT
last-modified:Fri, 30 Jan 2026 18:35:55 GMT
pragma:no-cache
server:nginx
x-request-id:253-23576165

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26426-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Directly measured"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26426-9","display" : "Directly measured"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"()\"\r\n16 0    : 0ms  : Validate \"[http://loinc.org#LA26426-9 (\"Directly measured\")]\"\r\n16 0    : 0ms  : Check \"http://loinc.org#LA26426-9\"\r\n16 0    : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#793

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000001.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:35:56 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:c5ab8c3f-0b56-4d83-b08d-925083d925f3
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:c5ab8c3f-0b56-4d83-b08d-925083d925f3
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000001.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#794

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:1000036","display":"inversion"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:c73a8ff4-9e01-498c-baa0-3524ce454b76
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:c73a8ff4-9e01-498c-baa0-3524ce454b76
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:1000036"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#795

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:1000036"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0002072"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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date:Fri, 30 Jan 2026 18:35:57 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:cf1ef527-37c0-408d-9a6b-3e0e204c8398
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:cf1ef527-37c0-408d-9a6b-3e0e204c8398
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:1000036"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}]}

#796

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:1000036","display":"inversion"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:35:57 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:b0586607-5b92-4a2b-9293-84032707867c
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:b0586607-5b92-4a2b-9293-84032707867c
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:1000036"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#797

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","code":"441262","display":"APOE1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:35:58 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:eb9957a9-63aa-407d-8cfb-5bfa0169e924
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:eb9957a9-63aa-407d-8cfb-5bfa0169e924
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"441262"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/clinvar"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/clinvar was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/clinvar"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/clinvar was not found"}]}

#798

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:613","display":"APOE"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:35:59 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:1d0b33d7-990d-4a9c-bcd0-25154509304e
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:1d0b33d7-990d-4a9c-bcd0-25154509304e
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:613"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#799

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:613"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:35:59 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:06633d3d-1f47-4158-823c-892563931415
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:06633d3d-1f47-4158-823c-892563931415
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:613"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}]}

#800

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:613","display":"APOE"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:36:00 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:49645233-c4d6-4cac-befb-42dc2cc70700
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:49645233-c4d6-4cac-befb-42dc2cc70700
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:613"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#801

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","code":"441262","display":"APOE1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json;charset=UTF-8
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server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:f004e6c0-5eea-4990-9de6-6e2c99ff7b6c
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:f004e6c0-5eea-4990-9de6-6e2c99ff7b6c
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"441262"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/clinvar"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/clinvar was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/clinvar"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/clinvar was not found"}]}

#802

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"PV00155","display":"CYP2D6*7.001"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:36:01 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:090c03ef-4c25-4ea8-9eb3-70742c3a6fc2
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:090c03ef-4c25-4ea8-9eb3-70742c3a6fc2
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"PV00155"},{"name":"system","valueUri":"http://www.pharmvar.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.pharmvar.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.pharmvar.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.pharmvar.org was not found"}]}

#803

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:2625","display":"CYP2D6"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:36:01 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:1182241e-93fa-4b24-9783-eefcc05470c9
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:1182241e-93fa-4b24-9783-eefcc05470c9
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:2625"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#804

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:2625"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:36:02 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:0fb4e284-5d67-4e9d-9840-01979b6a3836
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:0fb4e284-5d67-4e9d-9840-01979b6a3836
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:2625"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}]}

#805

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:2625","display":"CYP2D6"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:36:02 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:13815590-5bea-4f20-a3c7-c2dec3745c5d
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:13815590-5bea-4f20-a3c7-c2dec3745c5d
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:2625"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#806

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"PV00126","display":"CYP2D6*1.001"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:36:03 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:04d2beaf-d323-44d3-be55-479abdb0bb51
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:04d2beaf-d323-44d3-be55-479abdb0bb51
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"PV00126"},{"name":"system","valueUri":"http://www.pharmvar.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.pharmvar.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.pharmvar.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.pharmvar.org was not found"}]}

#807

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"PV00155","display":"CYP2D6*7.001"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:36:03 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:f1d7c479-dc0a-41ab-8cb3-287fb012b874
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:f1d7c479-dc0a-41ab-8cb3-287fb012b874
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"PV00155"},{"name":"system","valueUri":"http://www.pharmvar.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.pharmvar.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.pharmvar.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.pharmvar.org was not found"}]}

#808

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"PV00126","display":"CYP2D6*1.001"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:36:04 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:1bec84cf-720a-4782-a991-3dfa43bcb207
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:1bec84cf-720a-4782-a991-3dfa43bcb207
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"PV00126"},{"name":"system","valueUri":"http://www.pharmvar.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.pharmvar.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.pharmvar.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.pharmvar.org was not found"}]}

#809

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"18474-7","display":"HER2 Ag [Presence] in Tissue by Immune stain"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:998
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:36:06 GMT
last-modified:Fri, 30 Jan 2026 18:36:06 GMT
pragma:no-cache
server:nginx
x-request-id:253-23576295

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "18474-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "HER2 Ag [Presence] in Tissue by Immune stain"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "18474-7","display" : "HER2 Ag [Presence] in Tissue by Immune stain"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#18474-7 (\"HER2 Ag [Presence] in Tissue by Immune stain\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#18474-7\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#810

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:3430","display":"ERBB2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:36:06 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:93164f1a-43c6-4684-85a2-ad8b81f6dd3a
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:93164f1a-43c6-4684-85a2-ad8b81f6dd3a
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:3430"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#811

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:3430"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:36:07 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:ecb09bcf-dcd1-4497-8654-e6537dfbd60b
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:ecb09bcf-dcd1-4497-8654-e6537dfbd60b
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:3430"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}]}

#812

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:3430","display":"ERBB2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:36:07 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:1e81dcb2-6d8a-4561-883c-c844f20d1a2d
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:1e81dcb2-6d8a-4561-883c-c844f20d1a2d
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:3430"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#813

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"72382-5","display":"HER2 [Units/volume] in Tissue by Immunoassay"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:998
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:36:09 GMT
last-modified:Fri, 30 Jan 2026 18:36:09 GMT
pragma:no-cache
server:nginx
x-request-id:253-23576345

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "72382-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "HER2 [Units/volume] in Tissue by Immunoassay"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "72382-5","display" : "HER2 [Units/volume] in Tissue by Immunoassay"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#72382-5 (\"HER2 [Units/volume] in Tissue by Immunoassay\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#72382-5\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#814

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81291-7","display":"Variant ISCN"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:902
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:36:10 GMT
last-modified:Fri, 30 Jan 2026 18:36:10 GMT
pragma:no-cache
server:nginx
x-request-id:253-23576366

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81291-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Variant ISCN"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81291-7","display" : "Variant ISCN"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81291-7 (\"Variant ISCN\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81291-7\"\r\n16 16   : 16ms : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#815

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"https://iscn.karger.com","code":"46,XX,t(9;22)(q34;q4)"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:36:11 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:38dc55d2-32c8-47e4-9720-d673ac74b8a2
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:38dc55d2-32c8-47e4-9720-d673ac74b8a2
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"46,XX,t(9;22)(q34;q4)"},{"name":"system","valueUri":"https://iscn.karger.com"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system https://iscn.karger.com was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'https://iscn.karger.com' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"https://iscn.karger.com"},{"name":"message","valueString":"A definition for CodeSystem 'https://iscn.karger.com' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system https://iscn.karger.com was not found"}]}

#816

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"92818009","display":"Chronic myeloid leukemia"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1080
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:36:11 GMT
last-modified:Fri, 30 Jan 2026 18:36:11 GMT
pragma:no-cache
server:nginx
x-request-id:253-23576398

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "92818009"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Chronic myeloid leukemia"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "92818009","display" : "Chronic myeloid leukemia"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://snomed.info/sct#92818009 (\"Chronic myeloid leukemia\")]\"\r\n0 0     : 0ms  : Check \"http://snomed.info/sct#92818009\"\r\n0 0     : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#817

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"https://iscn.karger.com","code":"46,XX"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:36:12 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:aeffa83d-81c6-420d-af61-c573521d587e
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:aeffa83d-81c6-420d-af61-c573521d587e
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"46,XX"},{"name":"system","valueUri":"https://iscn.karger.com"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system https://iscn.karger.com was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'https://iscn.karger.com' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"https://iscn.karger.com"},{"name":"message","valueString":"A definition for CodeSystem 'https://iscn.karger.com' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system https://iscn.karger.com was not found"}]}

#818

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:3775","display":"FMR1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:36:12 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:84e17cf1-823f-40e8-a668-e5fa34be3a6b
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:84e17cf1-823f-40e8-a668-e5fa34be3a6b
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:3775"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#819

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:3775"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:36:13 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:5384d358-3982-49c7-aeae-acf85b8d7eab
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:5384d358-3982-49c7-aeae-acf85b8d7eab
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:3775"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}]}

#820

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:3775","display":"FMR1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:36:13 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:6264e797-f37b-4f44-92e2-853a4603e15b
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:6264e797-f37b-4f44-92e2-853a4603e15b
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:3775"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#821

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48001-2","display":"Cytogenetic (chromosome) location"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:965
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:36:15 GMT
last-modified:Fri, 30 Jan 2026 18:36:15 GMT
pragma:no-cache
server:nginx
x-request-id:253-23576439

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48001-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Cytogenetic (chromosome) location"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48001-2","display" : "Cytogenetic (chromosome) location"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48001-2 (\"Cytogenetic (chromosome) location\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48001-2\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#822

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_002024.5","display":"NM_002024.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:36:16 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:ffe9d261-1c6e-43fe-9db3-b0c7894cc8d9
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:ffe9d261-1c6e-43fe-9db3-b0c7894cc8d9
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NM_002024.5"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#823

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10]","display":"NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10]"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1010
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:36:16 GMT
last-modified:Fri, 30 Jan 2026 18:36:16 GMT
pragma:no-cache
server:nginx
x-request-id:253-23576472

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10]"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10] (\"NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10]\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10]\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#824

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10]"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1291
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:36:16 GMT
last-modified:Fri, 30 Jan 2026 18:36:16 GMT
pragma:no-cache
server:nginx
x-request-id:253-23576474

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10]"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10] (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10]\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n63 63   : 63ms : Code \"NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10]\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#825

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"44054006","display":"Diabetes mellitus type 2 (disorder)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1103
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:36:17 GMT
last-modified:Fri, 30 Jan 2026 18:36:17 GMT
pragma:no-cache
server:nginx
x-request-id:253-23576490

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "44054006"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Diabetes mellitus type II"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "44054006","display" : "Diabetes mellitus type 2 (disorder)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://snomed.info/sct#44054006 (\"Diabetes mellitus type 2 (disorder)\")]\"\r\n0 0     : 0ms  : Check \"http://snomed.info/sct#44054006\"\r\n0 0     : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#826

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:8565","display":"PABPN1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:36:18 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:acb96886-6214-4fd5-9a4a-39d9bdfcfb9e
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:acb96886-6214-4fd5-9a4a-39d9bdfcfb9e
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:8565"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#827

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:8565"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:36:18 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:b0e8b5c1-e3e4-401d-a33a-0a81f5fceb92
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:b0e8b5c1-e3e4-401d-a33a-0a81f5fceb92
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:8565"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}]}

#828

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:8565","display":"PABPN1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:36:19 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:5bfa7ff1-2f51-4061-9506-df2bd72d38ee
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:5bfa7ff1-2f51-4061-9506-df2bd72d38ee
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:8565"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#829

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_004643.4","display":"NM_004643.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:36:19 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:4e00c068-cc31-47a8-8277-e5c85ce2ba98
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:4e00c068-cc31-47a8-8277-e5c85ce2ba98
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NM_004643.4"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#830

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_004643.3:c.3GGC[14]","display":"NM_004643.3:c.3GGC[14]"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:850
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:36:20 GMT
last-modified:Fri, 30 Jan 2026 18:36:20 GMT
pragma:no-cache
server:nginx
x-request-id:253-23576526

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_004643.3:c.3GGC[14]"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_004643.3:c.3GGC[14]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_004643.3:c.3GGC[14] (\"NM_004643.3:c.3GGC[14]\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_004643.3:c.3GGC[14]\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#831

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_004643.3:c.3GGC[14]"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1131
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:36:20 GMT
last-modified:Fri, 30 Jan 2026 18:36:20 GMT
pragma:no-cache
server:nginx
x-request-id:253-23576529

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_004643.3:c.3GGC[14]"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_004643.3:c.3GGC[14]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_004643.3:c.3GGC[14] (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_004643.3:c.3GGC[14]\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n78 78   : 78ms : Code \"NM_004643.3:c.3GGC[14]\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#832

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","code":"503634","display":"NM_004643.3(PABPN1):c.3GGC[11] (p.Ala11_Gly12insAlaAlaAlaAla)"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:36:20 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:3895d3ad-1101-4408-84df-6ac5ade6ec37
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:3895d3ad-1101-4408-84df-6ac5ade6ec37
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"503634"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/clinvar"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/clinvar was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/clinvar"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/clinvar was not found"}]}

#833

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:644","display":"AR"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:36:21 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:66cca567-1f52-49fc-9489-19b84a746613
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:66cca567-1f52-49fc-9489-19b84a746613
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:644"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#834

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:644"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:36:21 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:65e9200d-3ae9-49fb-9ac9-2ef517bfeaad
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:65e9200d-3ae9-49fb-9ac9-2ef517bfeaad
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:644"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}]}

#835

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:644","display":"AR"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:36:22 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:da1cb4da-4176-4507-af38-4ef0db46b1bf
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:da1cb4da-4176-4507-af38-4ef0db46b1bf
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:644"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#836

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000044.6:c.7G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:812
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:36:22 GMT
last-modified:Fri, 30 Jan 2026 18:36:22 GMT
pragma:no-cache
server:nginx
x-request-id:253-23576563

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000044.6:c.7G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000044.6:c.7G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_000044.6:c.7G>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_000044.6:c.7G>A\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#837

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000044.6:c.7G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1111
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:36:23 GMT
last-modified:Fri, 30 Jan 2026 18:36:23 GMT
pragma:no-cache
server:nginx
x-request-id:253-23576568

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000044.6:c.7G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000044.6:c.7G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_000044.6:c.7G>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_000044.6:c.7G>A\"\r\n16 16   : 16ms : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n16 0    : 16ms : check code in (http://varnomen.hgvs.org) at Coding\r\n78 62   : 78ms : Code \"NM_000044.6:c.7G>A\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#838

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_000035.2:p.Val3Met","display":"NP_000035.2:p.Val3Met"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:845
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:36:23 GMT
last-modified:Fri, 30 Jan 2026 18:36:23 GMT
pragma:no-cache
server:nginx
x-request-id:253-23576572

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_000035.2:p.Val3Met"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_000035.2:p.Val3Met"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_000035.2:p.Val3Met (\"NP_000035.2:p.Val3Met\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_000035.2:p.Val3Met\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#839

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_000035.2:p.Val3Met"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1126
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:36:23 GMT
last-modified:Fri, 30 Jan 2026 18:36:23 GMT
pragma:no-cache
server:nginx
x-request-id:253-23576576

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_000035.2:p.Val3Met"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_000035.2:p.Val3Met"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_000035.2:p.Val3Met (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_000035.2:p.Val3Met\"\r\n15 15   : 15ms : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n15 0    : 15ms : check code in (http://varnomen.hgvs.org) at Coding\r\n78 63   : 78ms : Code \"NP_000035.2:p.Val3Met\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#840

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_000044.3","display":"NM_000044.6"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:36:23 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:57118f79-a38e-44e7-9aba-c2c5ecc2a875
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:57118f79-a38e-44e7-9aba-c2c5ecc2a875
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NM_000044.3"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#841

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000019.8:g.1171707G>A","display":"NC_000019.8:g.1171707G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:860
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:36:24 GMT
last-modified:Fri, 30 Jan 2026 18:36:24 GMT
pragma:no-cache
server:nginx
x-request-id:253-23576593

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000019.8:g.1171707G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000019.8:g.1171707G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n15 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n15 0    : 0ms  : Prepare include: \"()\"\r\n15 0    : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000019.8:g.1171707G>A (\"NC_000019.8:g.1171707G>A\")]\"\r\n15 0    : 0ms  : Check \"http://varnomen.hgvs.org#NC_000019.8:g.1171707G>A\"\r\n15 0    : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#842

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000019.8:g.1171707G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1141
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:36:24 GMT
last-modified:Fri, 30 Jan 2026 18:36:24 GMT
pragma:no-cache
server:nginx
x-request-id:253-23576602

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000019.8:g.1171707G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000019.8:g.1171707G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000019.8:g.1171707G>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000019.8:g.1171707G>A\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n78 78   : 78ms : Code \"NC_000019.8:g.1171707G>A\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#843

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"444734003","display":"Does not meet eligibility criteria for clinical trial"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"genetic-therapeutic-implications-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs","version":"4.0.0-cibuild","name":"GeneticTherapeuticImplicationsVS","title":"Genetic Therapeutic Implications","status":"active","experimental":false,"date":"2026-01-30T18:21:39+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for terms that describe a predicted ramification based on the presence of associated molecular finding(s).","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This material contains content from LOINC (http://loinc.org). LOINC is copyright © 1995-2020, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC® is a registered United States trademark of Regenstrief Institute, Inc.\nThis value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement.","compose":{"include":[{"system":"http://loinc.org","concept":[{"code":"LA10315-2","display":"Ultrarapid metabolizer"},{"code":"LA25391-6","display":"Normal metabolizer"},{"code":"LA25390-8","display":"Rapid metabolizer"},{"code":"LA10317-8","display":"Intermediate metabolizer"},{"code":"LA9657-3","display":"Poor metabolizer"},{"code":"LA19542-2","display":"Low Risk"},{"code":"LA19541-4","display":"High Risk"},{"code":"LA6676-6","display":"Resistant"},{"code":"LA6677-4","display":"Responsive"},{"code":"LA9660-7","display":"Presumed resistant"},{"code":"LA9661-5","display":"Presumed responsive"},{"code":"LA6682-4","display":"Unknown Significance"},{"code":"LA6675-8","display":"Benign"},{"code":"LA6674-1","display":"Presumed Benign"},{"code":"LA9662-3","display":"Presumed non-responsive"},{"code":"LA25392-4","display":"Increased function"},{"code":"LA25393-2","display":"Normal function"},{"code":"LA25395-7","display":"Decreased function"},{"code":"LA25394-0","display":"Poor function"}]},{"system":"http://snomed.info/sct","concept":[{"code":"444734003","display":"Does not meet eligibility criteria for clinical trial (finding)"},{"code":"399223003","display":"Patient eligible for clinical trial (finding)"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1963
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:36:25 GMT
last-modified:Fri, 30 Jan 2026 18:36:25 GMT
pragma:no-cache
server:nginx
x-request-id:253-23576611

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "444734003"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Does not meet eligibility criteria for clinical trial (finding)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "444734003","display" : "Does not meet eligibility criteria for clinical trial"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n32 32   : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-cibuild for validation purposes\r\n32 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n32 0    : 0ms  : Prepare include: \"(http://loinc.org)(LA10315-2,LA25391-6,LA25390-8,LA10317-8,LA9657-3,LA19542-2,LA19541-4,LA6676-6,LA6677-4,LA9660-7,LA9661-5,LA6682-4,LA6675-8,LA6674-1,LA9662-3,LA25392-4,LA25393-2,LA25395-7,LA25394-0)\"\r\n47 15   : 15ms : CodeSystem found: \"http://loinc.org|2.81\"\r\n47 0    : 15ms : Prepare include: \"(http://snomed.info/sct)(444734003,399223003)\"\r\n47 0    : 15ms : CodeSystem found: \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\"\r\n47 0    : 15ms : Validate \"[http://snomed.info/sct#444734003 (\"Does not meet eligibility criteria for clinical trial\")]\"\r\n47 0    : 15ms : Check \"http://snomed.info/sct#444734003\"\r\n47 0    : 15ms : CodeSystem found: http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201 for http://snomed.info/sct\r\n47 0    : 15ms : check code in (http://snomed.info/sct)(444734003,399223003) at CodeableConcept.coding[0]\r\n47 0    : 15ms : Code \"444734003\" found in http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\r\n"}]}

#844

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"444734003","display":"Does not meet eligibility criteria for clinical trial"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1181
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:36:25 GMT
last-modified:Fri, 30 Jan 2026 18:36:25 GMT
pragma:no-cache
server:nginx
x-request-id:253-23576614

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "444734003"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Does not meet eligibility criteria for clinical trial (finding)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "444734003","display" : "Does not meet eligibility criteria for clinical trial"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://snomed.info/sct#444734003 (\"Does not meet eligibility criteria for clinical trial\")]\"\r\n0 0     : 0ms  : Check \"http://snomed.info/sct#444734003\"\r\n0 0     : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#845

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://clinicaltrials.gov","code":"NCT03131453","display":"NCT03131453"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:36:25 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:33112270-ac1c-4dc4-bea8-c1cb33e93149
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:33112270-ac1c-4dc4-bea8-c1cb33e93149
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NCT03131453"},{"name":"system","valueUri":"http://clinicaltrials.gov"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://clinicaltrials.gov was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://clinicaltrials.gov' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://clinicaltrials.gov"},{"name":"message","valueString":"A definition for CodeSystem 'http://clinicaltrials.gov' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://clinicaltrials.gov was not found"}]}

#846

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"10828004","display":"Positive (qualifier value)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"observation-interpretation","meta":{"lastUpdated":"2019-11-01T09:29:23.356+11:00","profile":["http://hl7.org/fhir/StructureDefinition/shareablevalueset"]},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"oo"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"normative"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version","valueCode":"4.0.0"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":5}],"url":"http://hl7.org/fhir/ValueSet/observation-interpretation","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.399"}],"version":"4.0.1","name":"ObservationInterpretationCodes","title":"Observation Interpretation Codes","status":"active","experimental":false,"date":"2019-11-01T09:29:23+11:00","publisher":"FHIR Project team","contact":[{"telecom":[{"system":"url","value":"http://hl7.org/fhir"}]}],"description":"A categorical assessment, providing a rough qualitative interpretation of the observation value,    such as “normal”/ “abnormal”,”low” / “high”, “better” / “worse”, “susceptible” / “resistant”, “expected”/ “not expected”.    The value set is intended to be for ANY use where coded representation of an interpretation is needed.   \r\n   \r\n   Notes:\r\n   \r\n   This is being communicated in v2.x in OBX-8 (Observation Interpretation), in v3 in ObservationInterpretation (CWE) in R1 (Representative Realm) and in FHIR in    Observation.interpretation. Historically these values come from the laboratory domain, and these codes are extensively    used. The value set binding is extensible, so codes outside the value set that are needed for interpretation concepts    (i.e. particular meanings) that are not included in the value set can be used, and these new codes may also be added to    the value set and published in a future version.","compose":{"include":[{"system":"http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation"}]}}},{"name":"tx-resource","resource":{"resourceType":"CodeSystem","id":"v3-ObservationInterpretation","language":"en","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"url":"http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.5.83"}],"version":"3.0.0","name":"ObservationInterpretation","title":"ObservationInterpretation","status":"active","experimental":false,"date":"2019-03-20","publisher":"Health Level Seven International","contact":[{"telecom":[{"system":"url","value":"http://hl7.org"},{"system":"email","value":"hq@HL7.org"}]}],"description":"One or more codes providing a rough qualitative interpretation of the observation, such as \"normal\" / \"abnormal\", \"low\" / \"high\", \"better\" / \"worse\", \"resistant\" / \"susceptible\", \"expected\" / \"not expected\". The value set is intended to be for ANY use where coded representation of an interpretation is needed.","copyright":"This material derives from the HL7 Terminology THO. THO is copyright ©1989+ Health Level Seven International and is made available under the CC0 designation. For more licensing information see: https://terminology.hl7.org/license.html","caseSensitive":true,"hierarchyMeaning":"is-a","content":"complete","property":[{"code":"internalId","uri":"http://terminology.hl7.org/CodeSystem/utg-concept-properties#v3-internal-id","description":"The internal identifier for the concept in the HL7 Access database repository.","type":"code"},{"code":"notSelectable","uri":"http://hl7.org/fhir/concept-properties#notSelectable","description":"Indicates that the code is abstract - only intended to be used as a selector for other concepts","type":"boolean"},{"code":"status","uri":"http://hl7.org/fhir/concept-properties#status","description":"A property that indicates the status of the concept. One of active, experimental, deprecated, or retired.","type":"code"},{"code":"deprecationDate","uri":"http://hl7.org/fhir/concept-properties#deprecationDate","description":"The date at which a concept was deprecated. Concepts that are deprecated but not inactive can still be used, but their use is discouraged.","type":"dateTime"},{"code":"subsumedBy","uri":"http://hl7.org/fhir/concept-properties#parent","description":"The concept code of a parent concept","type":"code"}],"concept":[{"code":"_GeneticObservationInterpretation","display":"GeneticObservationInterpretation","definition":"Codes that specify interpretation of genetic analysis, such as \"positive\", \"negative\", \"carrier\", \"responsive\", etc.","property":[{"code":"notSelectable","valueBoolean":true},{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"22646"}]},{"code":"_ObservationInterpretationChange","display":"ObservationInterpretationChange","definition":"Interpretations of change of quantity and/or severity. At most one of B or W and one of U or D allowed.","property":[{"code":"notSelectable","valueBoolean":true},{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"21090"}]},{"code":"_ObservationInterpretationExceptions","display":"ObservationInterpretationExceptions","definition":"Technical exceptions resulting in the inability to provide an interpretation. At most one allowed. Does not imply normality or severity.","property":[{"code":"notSelectable","valueBoolean":true},{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"21091"}]},{"code":"_ObservationInterpretationNormality","display":"ObservationInterpretationNormality","definition":"Interpretation of normality or degree of abnormality (including critical or \"alert\" level). Concepts in this category are mutually exclusive, i.e., at most one is allowed.","property":[{"code":"notSelectable","valueBoolean":true},{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"21092"}]},{"code":"_ObservationInterpretationSusceptibility","display":"ObservationInterpretationSusceptibility","definition":"Interpretations of anti-microbial susceptibility testing results (microbiology). At most one allowed.","property":[{"code":"notSelectable","valueBoolean":true},{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"21093"}]},{"code":"EX","display":"outside threshold","definition":"The observation/test result is interpreted as being outside the inclusion range for a particular protocol within which the result is being reported.\r\n\r\n**Example:** A positive result on a Hepatitis screening test.\r\n\r\n*Open Issue:* EX, HX, LX: These three concepts do not seem to meet a clear need in the vocabulary, and their use in observation interpretation appears likely to be covered by other existing concepts (e.g., A, H, L). The only apparent significant difference is their reference to use in protocols for exclusion of study subjects. These concepts/codes were proposed by RCRIM for use in the CTLaboratory message. They were submitted and approved in the November 2005 Harmonization cycle in proposal \"030103C\\_VOCAB\\_RCRIM\\_l\\_quade\\_RCRIM Obs Interp\\_20051028154455\". However, this proposal was not fully implemented in the vocabulary. The proposal recommended creation of the x\\_ClinicalResearchExclusion domain in ObservationInterpretation with a value set including those three concepts/codes, but there is no subdomain of that name or equivalent with a binding to either of the value sets that contain these concepts/codes. Members of the OO WG have recently attempted to contact members of RCRIM regarding these concepts, both by email and at the recent WGM in Atlanta, without response. It is felt by OO that the best course of action to take at this time is to add this comprehensive Open Issue rather than deprecate these three concepts at this time, until further discussion is held.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"21634"}]},{"code":"HM","display":"Hold for Medical Review","definition":"Hold for Medical Review\r\n\r\n*Usage Note:* This code is not intended for use in V3 artifacts. It is included in the code system to maintain alignment with the V2 Table 0078 \"Interpretation Codes.\"","property":[{"code":"status","valueCode":"deprecated"},{"code":"deprecationDate","valueDateTime":"2016-11-10"},{"code":"internalId","valueCode":"23790"}]},{"code":"ObservationInterpretationDetection","display":"ObservationInterpretationDetection","definition":"Interpretations of the presence or absence of a component / analyte or organism in a test or of a sign in a clinical observation. In keeping with laboratory data processing practice, these concepts provide a categorical interpretation of the \"meaning\" of the quantitative value for the same observation.","property":[{"code":"notSelectable","valueBoolean":true},{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"22805"}]},{"code":"ObservationInterpretationExpectation","display":"ObservationInterpretationExpectation","definition":"Interpretation of the observed result taking into account additional information (contraindicators) about the patient's situation. Concepts in this category are mutually exclusive, i.e., at most one is allowed.","property":[{"code":"notSelectable","valueBoolean":true},{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23723"}]},{"code":"OBX","display":"Interpretation qualifiers in separate OBX segments","definition":"Interpretation qualifiers in separate OBX segments\r\n\r\n*Usage Note:* This code is not intended for use in V3 artifacts. It is included in the code system to maintain alignment with the V2 Table 0078 \"Interpretation Codes.\"","property":[{"code":"status","valueCode":"deprecated"},{"code":"deprecationDate","valueDateTime":"2016-11-10"},{"code":"internalId","valueCode":"23789"}]},{"code":"ReactivityObservationInterpretation","display":"ReactivityObservationInterpretation","definition":"Interpretations of the presence and level of reactivity of the specified component / analyte with the reagent in the performed laboratory test.","property":[{"code":"notSelectable","valueBoolean":true},{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23568"}]},{"code":"CAR","display":"Carrier","definition":"The patient is considered as carrier based on the testing results. A carrier is an individual who carries an altered form of a gene which can lead to having a child or offspring in future generations with a genetic disorder.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23559"},{"code":"subsumedBy","valueCode":"_GeneticObservationInterpretation"}]},{"code":"Carrier","display":"Carrier","definition":"The patient is considered as carrier based on the testing results. A carrier is an individual who carries an altered form of a gene which can lead to having a child or offspring in future generations with a genetic disorder.\r\n\r\n***Deprecation Comment:*** This code is currently the same string as the print name for this concept and is inconsistent with the conventions being used for the other codes in the coding system, as it is a full word with initial capitalization, rather than an all upper case mnemonic. The recommendation from OO is to deprecate the code \"Carrier\" and to add \"CAR\" as the new active code representation for this concept.","property":[{"code":"status","valueCode":"deprecated"},{"code":"deprecationDate","valueDateTime":"2013-07-28"},{"code":"internalId","valueCode":"22647"},{"code":"subsumedBy","valueCode":"_GeneticObservationInterpretation"}]},{"code":"B","display":"Better","definition":"The current result or observation value has improved compared to the previous result or observation value (the change is significant as defined in the respective test procedure).\r\n\r\n\\[Note: This can be applied to quantitative or qualitative observations.\\]","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10215"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationChange"}]},{"code":"D","display":"Significant change down","definition":"The current result has decreased from the previous result for a quantitative observation (the change is significant as defined in the respective test procedure).","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10218"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationChange"}]},{"code":"U","display":"Significant change up","definition":"The current result has increased from the previous result for a quantitative observation (the change is significant as defined in the respective test procedure).","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10217"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationChange"}]},{"code":"W","display":"Worse","definition":"The current result or observation value has degraded compared to the previous result or observation value (the change is significant as defined in the respective test procedure).\r\n\r\n\\[Note: This can be applied to quantitative or qualitative observations.\\]","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10216"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationChange"}]},{"code":"<","display":"Off scale low","definition":"The result is below the minimum detection limit (the test procedure or equipment is the limiting factor).\r\n\r\nSynonyms: Below analytical limit, low off scale.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10226"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationExceptions"}]},{"code":">","display":"Off scale high","definition":"The result is above the maximum quantifiable limit (the test procedure or equipment is the limiting factor).\r\n\r\nSynonyms: Above analytical limit, high off scale.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10227"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationExceptions"}]},{"code":"AC","display":"Anti-complementary substances present","definition":"A valid result cannot be obtained for the specified component / analyte due to the presence of anti-complementary substances in the sample.\r\n\r\n***Deprecation Comment:*** This code is being deprecated to match the status in V2 Table 0078 \"Interpretation Codes.","property":[{"code":"status","valueCode":"deprecated"},{"code":"deprecationDate","valueDateTime":"2016-11-10"},{"code":"internalId","valueCode":"23564"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationExceptions"}]},{"code":"IE","display":"Insufficient evidence","definition":"There is insufficient evidence that the species in question is a good target for therapy with the drug. A categorical interpretation is not possible.\r\n\r\n\\[Note: A MIC with \"IE\" and/or a comment may be reported (without an accompanying S, I or R-categorization).\\]","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23567"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationExceptions"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationSusceptibility"}]},{"code":"QCF","display":"Quality control failure","definition":"A result cannot be considered valid for the specified component / analyte or organism due to failure in the quality control testing component.\r\n\r\n***Deprecation Comment:*** This code is being deprecated to match the status in V2 Table 0078 \"Interpretation Codes.","property":[{"code":"status","valueCode":"deprecated"},{"code":"deprecationDate","valueDateTime":"2016-11-10"},{"code":"internalId","valueCode":"23565"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationExceptions"}]},{"code":"TOX","display":"Cytotoxic substance present","definition":"A valid result cannot be obtained for the specified organism or cell line due to the presence of cytotoxic substances in the sample or culture.\r\n\r\n***Deprecation Comment:*** This code is being deprecated to match the status in V2 Table 0078 \"Interpretation Codes.","property":[{"code":"status","valueCode":"deprecated"},{"code":"deprecationDate","valueDateTime":"2016-11-10"},{"code":"internalId","valueCode":"23566"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationExceptions"}]},{"code":"A","display":"Abnormal","definition":"The result or observation value is outside the reference range or expected norm (as defined for the respective test procedure).\r\n\r\n\\[Note: Typically applies to non-numeric results.\\]","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10208"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationNormality"}]},{"code":"N","display":"Normal","definition":"The result or observation value is within the reference range or expected norm (as defined for the respective test procedure).\r\n\r\n\\[Note: Applies to numeric or non-numeric results.\\]","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10207"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationNormality"}]},{"code":"I","display":"Intermediate","definition":"Bacterial strain inhibited in vitro by a concentration of an antimicrobial agent that is associated with uncertain therapeutic effect. Reference: CLSI (http://www.clsi.org/Content/NavigationMenu/Resources/HarmonizedTerminologyDatabase/Harmonized\\_Terminolo.htm) Projects: ISO 20776-1, ISO 20776-2\r\n\r\n\\[Note 1: Bacterial strains are categorized as intermediate by applying the appropriate breakpoints in a defined phenotypic test system.\\]\r\n\r\n\\[Note 2: This class of susceptibility implies that an infection due to the isolate can be appropriately treated in body sites where the drugs are physiologically concentrated or when a high dosage of drug can be used.\\]\r\n\r\n\\[Note 3: This class also indicates a \"buffer zone,\" to prevent small, uncontrolled, technical factors from causing major discrepancies in interpretations.\\]\r\n\r\n\\[Note 4: These breakpoints can be altered due to changes in circumstances (e.g., changes in commonly used drug dosages, emergence of new resistance mechanisms).\\]","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10221"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationSusceptibility"}]},{"code":"MS","display":"moderately susceptible","definition":"The patient is considered as carrier based on the testing results. A carrier is an individual who carries an altered form of a gene which can lead to having a child or offspring in future generations with a genetic disorder.\r\n\r\n***Deprecation Comment:*** This antimicrobial susceptibility test interpretation concept is recommended by OO to be deprecated as it is no longer recommended for use in susceptibility testing by CLSI (reference CLSI document M100-S22; Vol. 32 No.3; CLSI Performance Standards for Antimicrobial Susceptibility Testing; Twenty-Second Informational Supplement. Jan 2012).","property":[{"code":"status","valueCode":"deprecated"},{"code":"deprecationDate","valueDateTime":"2013-07-28"},{"code":"internalId","valueCode":"10222"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationSusceptibility"}]},{"code":"NCL","display":"No CLSI defined breakpoint","definition":"Use when not enough clinical trial data published by the Clinical and Laboratory Standards Institutes (CLSI) is available to establish the breakpoints for susceptible / intermediate and resistant.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23886"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationSusceptibility"}]},{"code":"NS","display":"Non-susceptible","definition":"A category used for isolates for which only a susceptible interpretive criterion has been designated because of the absence or rare occurrence of resistant strains. Isolates that have MICs above or zone diameters below the value indicated for the susceptible breakpoint should be reported as non-susceptible.\r\n\r\nNOTE 1: An isolate that is interpreted as non-susceptible does not necessarily mean that the isolate has a resistance mechanism. It is possible that isolates with MICs above the susceptible breakpoint that lack resistance mechanisms may be encountered within the wild-type distribution subsequent to the time the susceptible-only breakpoint is set.\r\n\r\nNOTE 2: For strains yielding results in the \"nonsusceptible\" category, organism identification and antimicrobial susceptibility test results should be confirmed.\r\n\r\nSynonym: decreased susceptibility.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23557"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationSusceptibility"}]},{"code":"R","display":"Resistant","definition":"Bacterial strain inhibited in vitro by a concentration of an antimicrobial agent that is associated with a high likelihood of therapeutic failure. Reference: CLSI (http://www.clsi.org/Content/NavigationMenu/Resources/HarmonizedTerminologyDatabase/Harmonized\\_Terminolo.htm) Projects: ISO 20776-1, ISO 20776-2\r\n\r\n\\[Note 1: Bacterial strains are categorized as resistant by applying the appropriate breakpoints in a defined phenotypic test system.\\]\r\n\r\n\\[Note 2: This breakpoint can be altered due to changes in circumstances (e.g., changes in commonly used drug dosages, emergence of new resistance mechanisms).\\]","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10220"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationSusceptibility"}]},{"code":"S","display":"Susceptible","definition":"Bacterial strain inhibited by in vitro concentration of an antimicrobial agent that is associated with a high likelihood of therapeutic success. Reference: CLSI (http://www.clsi.org/Content/NavigationMenu/Resources/HarmonizedTerminologyDatabase/Harmonized\\_Terminolo.htm) Synonym (earlier term): Sensitive Projects: ISO 20776-1, ISO 20776-2\r\n\r\n\\[Note 1: Bacterial strains are categorized as susceptible by applying the appropriate breakpoints in a defined phenotypic system.\\]\r\n\r\n\\[Note 2: This breakpoint can be altered due to changes in circumstances (e.g., changes in commonly used drug dosages, emergence of new resistance mechanisms).\\]","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10223"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationSusceptibility"}]},{"code":"VS","display":"very susceptible","definition":"The patient is considered as carrier based on the testing results. A carrier is an individual who carries an altered form of a gene which can lead to having a child or offspring in future generations with a genetic disorder.\r\n\r\n***Deprecation Comment:*** This antimicrobial susceptibility test interpretation concept is recommended by OO to be deprecated as it is no longer recommended for use in susceptibility testing by CLSI (reference CLSI document M100-S22; Vol. 32 No.3; CLSI Performance Standards for Antimicrobial Susceptibility Testing; Twenty-Second Informational Supplement. Jan 2012).","property":[{"code":"status","valueCode":"deprecated"},{"code":"deprecationDate","valueDateTime":"2013-07-28"},{"code":"internalId","valueCode":"10224"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationSusceptibility"}]},{"code":"AA","display":"Critical abnormal","definition":"The result or observation value is outside a reference range or expected norm at a level at which immediate action should be considered for patient safety (as defined for the respective test procedure).\r\n\r\n\\[Note: Typically applies to non-numeric results. Analogous to critical/panic limits for numeric results.\\]","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10211"},{"code":"subsumedBy","valueCode":"A"}]},{"code":"H","display":"High","definition":"The result for a quantitative observation is above the upper limit of the reference range (as defined for the respective test procedure).\r\n\r\nSynonym: Above high normal","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10210"},{"code":"subsumedBy","valueCode":"A"}]},{"code":"L","display":"Low","definition":"The result for a quantitative observation is below the lower limit of the reference range (as defined for the respective test procedure).\r\n\r\nSynonym: Below low normal","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10209"},{"code":"subsumedBy","valueCode":"A"}]},{"code":"HH","display":"Critical high","definition":"The result for a quantitative observation is above a reference level at which immediate action should be considered for patient safety (as defined for the respective test procedure).\r\n\r\nSynonym: Above upper panic limits.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10213"},{"code":"subsumedBy","valueCode":"AA"},{"code":"subsumedBy","valueCode":"H>"},{"code":"subsumedBy","valueCode":"HU"}]},{"code":"LL","display":"Critical low","definition":"The result for a quantitative observation is below a reference level at which immediate action should be considered for patient safety (as defined for the respective test procedure).\r\n\r\nSynonym: Below lower panic limits.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10212"},{"code":"subsumedBy","valueCode":"AA"},{"code":"subsumedBy","valueCode":"L<"},{"code":"subsumedBy","valueCode":"LU"}]},{"code":"HX","display":"above high threshold","definition":"The observation/test result is interpreted as being outside the inclusion range for a particular protocol within which the result is being reported.\r\n\r\n**Example:** A positive result on a Hepatitis screening test.\r\n\r\n*Open Issue:* EX, HX, LX: These three concepts do not seem to meet a clear need in the vocabulary, and their use in observation interpretation appears likely to be covered by other existing concepts (e.g., A, H, L). The only apparent significant difference is their reference to use in protocols for exclusion of study subjects. These concepts/codes were proposed by RCRIM for use in the CTLaboratory message. They were submitted and approved in the November 2005 Harmonization cycle in proposal \"030103C\\_VOCAB\\_RCRIM\\_l\\_quade\\_RCRIM Obs Interp\\_20051028154455\". However, this proposal was not fully implemented in the vocabulary. The proposal recommended creation of the x\\_ClinicalResearchExclusion domain in ObservationInterpretation with a value set including those three concepts/codes, but there is no subdomain of that name or equivalent with a binding to either of the value sets that contain these concepts/codes. Members of the OO WG have recently attempted to contact members of RCRIM regarding these concepts, both by email and at the recent WGM in Atlanta, without response. It is felt by OO that the best course of action to take at this time is to add this comprehensive Open Issue rather than deprecate these three concepts at this time, until further discussion is held.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"21636"},{"code":"subsumedBy","valueCode":"EX"}]},{"code":"LX","display":"below low threshold","definition":"The numeric observation/test result is interpreted as being below the low threshold value for a particular protocol within which the result is being reported.\r\n\r\n**Example:** A Total White Blood Cell Count falling below a protocol-defined threshold value of 3000/mm^3\r\n\r\n*Open Issue:* EX, HX, LX: These three concepts do not seem to meet a clear need in the vocabulary, and their use in observation interpretation appears likely to be covered by other existing concepts (e.g., A, H, L). The only apparent significant difference is their reference to use in protocols for exclusion of study subjects. These concepts/codes were proposed by RCRIM for use in the CTLaboratory message. They were submitted and approved in the November 2005 Harmonization cycle in proposal \"030103C\\_VOCAB\\_RCRIM\\_l\\_quade\\_RCRIM Obs Interp\\_20051028154455\". However, this proposal was not fully implemented in the vocabulary. The proposal recommended creation of the x\\_ClinicalResearchExclusion domain in ObservationInterpretation with a value set including those three concepts/codes, but there is no subdomain of that name or equivalent with a binding to either of the value sets that contain these concepts/codes. Members of the OO WG have recently attempted to contact members of RCRIM regarding these concepts, both by email and at the recent WGM in Atlanta, without response. It is felt by OO that the best course of action to take at this time is to add this comprehensive Open Issue rather than deprecate these three concepts at this time, until further discussion is held.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"21635"},{"code":"subsumedBy","valueCode":"EX"}]},{"code":"H>","display":"Significantly high","definition":"A test result that is significantly higher than the reference (normal) or therapeutic interval, but has not reached the critically high value and might need special attention, as defined by the laboratory or the clinician.\r\n\r\n\\[Note: This level is situated between 'H' and 'HH'.\\]\r\n\r\n*Deprecation Comment:* The code 'H>' is being deprecated in order to align with the use of the code 'HU' for \"Very high\" in V2 Table 0078 \"Interpretation Codes\".\r\n\r\n\\[Note: The use of code 'H>' is non-preferred, as this code is deprecated and on track to be retired; use code 'HU' instead.","property":[{"code":"status","valueCode":"deprecated"},{"code":"deprecationDate","valueDateTime":"2015-03-23"},{"code":"internalId","valueCode":"23560"},{"code":"subsumedBy","valueCode":"H"}]},{"code":"HU","display":"Significantly high","definition":"A test result that is significantly higher than the reference (normal) or therapeutic interval, but has not reached the critically high value and might need special attention, as defined by the laboratory or the clinician.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23742"},{"code":"subsumedBy","valueCode":"H"}]},{"code":"E","display":"Equivocal","definition":"The test or procedure was successfully performed, but the results are borderline and can neither be declared positive / negative nor detected / not detected according to the current established criteria.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23732"},{"code":"subsumedBy","valueCode":"IND"}]},{"code":"L<","display":"Significantly low","definition":"A test result that is significantly lower than the reference (normal) or therapeutic interval, but has not reached the critically low value and might need special attention, as defined by the laboratory or the clinician.\r\n\r\n\\[Note: This level is situated between 'L' and 'LL'.\\]\r\n\r\n*Deprecation Comment:* The code 'L<' is being deprecated in order to align with the use of the code 'LU' for \"Very low\" in V2 Table 0078 \"Interpretation Codes\".\r\n\r\n\\[Note: The use of code 'L<' is non-preferred, as this code is deprecated and on track to be retired; use code 'LU' instead.","property":[{"code":"status","valueCode":"deprecated"},{"code":"deprecationDate","valueDateTime":"2015-03-23"},{"code":"internalId","valueCode":"23561"},{"code":"subsumedBy","valueCode":"L"}]},{"code":"LU","display":"Significantly low","definition":"A test result that is significantly lower than the reference (normal) or therapeutic interval, but has not reached the critically low value and might need special attention, as defined by the laboratory or the clinician.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23743"},{"code":"subsumedBy","valueCode":"L"}]},{"code":"ND","display":"Not detected","definition":"The presence of the specified component / analyte, organism or clinical sign could not be determined within the limit of detection of the performed test or procedure.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23563"},{"code":"subsumedBy","valueCode":"NEG"}]},{"code":"IND","display":"Indeterminate","definition":"The specified component / analyte, organism or clinical sign could neither be declared positive / negative nor detected / not detected by the performed test or procedure.\r\n\r\n*Usage Note:* For example, if the specimen was degraded, poorly processed, or was missing the required anatomic structures, then \"indeterminate\" (i.e. \"cannot be determined\") is the appropriate response, not \"equivocal\".","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"22807"},{"code":"subsumedBy","valueCode":"ObservationInterpretationDetection"}]},{"code":"NEG","display":"Negative","definition":"An absence finding of the specified component / analyte, organism or clinical sign based on the established threshold of the performed test or procedure.\r\n\r\n\\[Note: Negative does not necessarily imply the complete absence of the specified item.\\]","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"22808"},{"code":"subsumedBy","valueCode":"ObservationInterpretationDetection"}]},{"code":"POS","display":"Positive","definition":"A presence finding of the specified component / analyte, organism or clinical sign based on the established threshold of the performed test or procedure.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"22806"},{"code":"subsumedBy","valueCode":"ObservationInterpretationDetection"}]},{"code":"EXP","display":"Expected","definition":"This result has been evaluated in light of known contraindicators. Once those contraindicators have been taken into account the result is determined to be \"Expected\" (e.g., presence of drugs in a patient that is taking prescription medication for pain management).","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23724"},{"code":"subsumedBy","valueCode":"ObservationInterpretationExpectation"}]},{"code":"UNE","display":"Unexpected","definition":"This result has been evaluated in light of known contraindicators. Once those contraindicators have been taken into account the result is determined to be \"Unexpected\" (e.g., presence of non-prescribed drugs in a patient that is taking prescription medication for pain management).","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23725"},{"code":"subsumedBy","valueCode":"ObservationInterpretationExpectation"}]},{"code":"DET","display":"Detected","definition":"The measurement of the specified component / analyte, organism or clinical sign above the limit of detection of the performed test or procedure.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23562"},{"code":"subsumedBy","valueCode":"POS"}]},{"code":"SYN-R","display":"Synergy - resistant","definition":"A category for isolates where the bacteria (e.g. enterococci) are not susceptible in vitro to a combination therapy (e.g., high-level aminoglycoside and cell wall active agent). This is predictive that this combination therapy will not be effective.\r\n\r\n*Usage Note:* Since the use of penicillin or ampicillin alone often results in treatment failure of serious enterococcal or other bacterial infections, combination therapy is usually indicated to enhance bactericidal activity. The synergy between a cell wall active agent (such as penicillin, ampicillin, or vancomycin) and an aminoglycoside (such as gentamicin, kanamycin or streptomycin) is best predicted by screening for high-level bacterial resistance to the aminoglycoside.\r\n\r\n*Open Issue:* The print name of the code is very general and the description is very specific to a pair of classes of agents, which may lead to confusion of these concepts in the future should other synergies be found.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23621"},{"code":"subsumedBy","valueCode":"R"}]},{"code":"NR","display":"Non-reactive","definition":"An absence finding used to indicate that the specified component / analyte did not react measurably with the reagent.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23569"},{"code":"subsumedBy","valueCode":"ReactivityObservationInterpretation"}]},{"code":"RR","display":"Reactive","definition":"A presence finding used to indicate that the specified component / analyte reacted with the reagent above the reliably measurable limit of the performed test.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23570"},{"code":"subsumedBy","valueCode":"ReactivityObservationInterpretation"}]},{"code":"WR","display":"Weakly reactive","definition":"A weighted presence finding used to indicate that the specified component / analyte reacted with the reagent, but below the reliably measurable limit of the performed test.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23571"},{"code":"subsumedBy","valueCode":"RR"}]},{"code":"SDD","display":"Susceptible-dose dependent","definition":"A category that includes isolates with antimicrobial agent minimum inhibitory concentrations (MICs) that approach usually attainable blood and tissue levels and for which response rates may be lower than for susceptible isolates.\r\n\r\nReference: CLSI document M44-A2 2009 \"Method for antifungal disk diffusion susceptibility testing of yeasts; approved guideline - second edition\" - page 2.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23558"},{"code":"subsumedBy","valueCode":"S"}]},{"code":"SYN-S","display":"Synergy - susceptible","definition":"A category for isolates where the bacteria (e.g. enterococci) are susceptible in vitro to a combination therapy (e.g., high-level aminoglycoside and cell wall active agent). This is predictive that this combination therapy will be effective.\r\n\r\n*Usage Note:* Since the use of penicillin or ampicillin alone often results in treatment failure of serious enterococcal or other bacterial infections, combination therapy is usually indicated to enhance bactericidal activity. The synergy between a cell wall active agent (such as penicillin, ampicillin, or vancomycin) and an aminoglycoside (such as gentamicin, kanamycin or streptomycin) is best predicted by screening for high-level bacterial resistance to the aminoglycoside.\r\n\r\n*Open Issue:* The print name of the code is very general and the description is very specific to a pair of classes of agents, which may lead to confusion of these concepts in the future should other synergies be found.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23620"},{"code":"subsumedBy","valueCode":"S"}]}]}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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last-modified:Fri, 30 Jan 2026 18:36:25 GMT
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#847

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:3689","display":"FGFR2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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x-request-id:e3327941-7d10-49fd-86af-ece18ba49c31
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:3689"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#848

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:3689"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:3689"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}]}

#849

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:3689","display":"FGFR2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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date:Fri, 30 Jan 2026 18:36:27 GMT
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x-request-id:31a772d9-7fcf-49d3-9541-b1c17e973ba6
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:3689"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#850

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000010.11:g.121498525T>G","display":"NC_000010.11:g.121498525T>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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date:Fri, 30 Jan 2026 18:36:27 GMT
last-modified:Fri, 30 Jan 2026 18:36:27 GMT
pragma:no-cache
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000010.11:g.121498525T>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000010.11:g.121498525T>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000010.11:g.121498525T>G (\"NC_000010.11:g.121498525T>G\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000010.11:g.121498525T>G\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#851

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000010.11:g.121498525T>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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last-modified:Fri, 30 Jan 2026 18:36:27 GMT
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x-request-id:253-23576665

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000010.11:g.121498525T>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000010.11:g.121498525T>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n15 15   : 15ms : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n15 0    : 15ms : Validate \"[http://varnomen.hgvs.org#NC_000010.11:g.121498525T>G (\"\")]\"\r\n15 0    : 15ms : Check \"http://varnomen.hgvs.org#NC_000010.11:g.121498525T>G\"\r\n15 0    : 15ms : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n15 0    : 15ms : check code in (http://varnomen.hgvs.org) at Coding\r\n78 63   : 78ms : Code \"NC_000010.11:g.121498525T>G\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#852

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"399223003","display":"Patient eligible for clinical trial"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"genetic-therapeutic-implications-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs","version":"4.0.0-cibuild","name":"GeneticTherapeuticImplicationsVS","title":"Genetic Therapeutic Implications","status":"active","experimental":false,"date":"2026-01-30T18:21:39+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for terms that describe a predicted ramification based on the presence of associated molecular finding(s).","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This material contains content from LOINC (http://loinc.org). LOINC is copyright © 1995-2020, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC® is a registered United States trademark of Regenstrief Institute, Inc.\nThis value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement.","compose":{"include":[{"system":"http://loinc.org","concept":[{"code":"LA10315-2","display":"Ultrarapid metabolizer"},{"code":"LA25391-6","display":"Normal metabolizer"},{"code":"LA25390-8","display":"Rapid metabolizer"},{"code":"LA10317-8","display":"Intermediate metabolizer"},{"code":"LA9657-3","display":"Poor metabolizer"},{"code":"LA19542-2","display":"Low Risk"},{"code":"LA19541-4","display":"High Risk"},{"code":"LA6676-6","display":"Resistant"},{"code":"LA6677-4","display":"Responsive"},{"code":"LA9660-7","display":"Presumed resistant"},{"code":"LA9661-5","display":"Presumed responsive"},{"code":"LA6682-4","display":"Unknown Significance"},{"code":"LA6675-8","display":"Benign"},{"code":"LA6674-1","display":"Presumed Benign"},{"code":"LA9662-3","display":"Presumed non-responsive"},{"code":"LA25392-4","display":"Increased function"},{"code":"LA25393-2","display":"Normal function"},{"code":"LA25395-7","display":"Decreased function"},{"code":"LA25394-0","display":"Poor function"}]},{"system":"http://snomed.info/sct","concept":[{"code":"444734003","display":"Does not meet eligibility criteria for clinical trial (finding)"},{"code":"399223003","display":"Patient eligible for clinical trial (finding)"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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server:nginx
x-request-id:253-23576667

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "399223003"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Patient eligible for clinical trial (finding)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "399223003","display" : "Patient eligible for clinical trial"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-cibuild for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"(http://loinc.org)(LA10315-2,LA25391-6,LA25390-8,LA10317-8,LA9657-3,LA19542-2,LA19541-4,LA6676-6,LA6677-4,LA9660-7,LA9661-5,LA6682-4,LA6675-8,LA6674-1,LA9662-3,LA25392-4,LA25393-2,LA25395-7,LA25394-0)\"\r\n16 0    : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n16 0    : 0ms  : Prepare include: \"(http://snomed.info/sct)(444734003,399223003)\"\r\n16 0    : 0ms  : CodeSystem found: \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\"\r\n16 0    : 0ms  : Validate \"[http://snomed.info/sct#399223003 (\"Patient eligible for clinical trial\")]\"\r\n16 0    : 0ms  : Check \"http://snomed.info/sct#399223003\"\r\n16 0    : 0ms  : CodeSystem found: http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201 for http://snomed.info/sct\r\n16 0    : 0ms  : check code in (http://snomed.info/sct)(444734003,399223003) at CodeableConcept.coding[0]\r\n16 0    : 0ms  : Code \"399223003\" found in http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\r\n"}]}

#853

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"399223003","display":"Patient eligible for clinical trial"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1127
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:36:28 GMT
last-modified:Fri, 30 Jan 2026 18:36:28 GMT
pragma:no-cache
server:nginx
x-request-id:253-23576669

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "399223003"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Patient eligible for clinical trial (finding)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "399223003","display" : "Patient eligible for clinical trial"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://snomed.info/sct#399223003 (\"Patient eligible for clinical trial\")]\"\r\n0 0     : 0ms  : Check \"http://snomed.info/sct#399223003\"\r\n0 0     : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#854

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"254837009","display":"Breast Cancer"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1063
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:36:28 GMT
last-modified:Fri, 30 Jan 2026 18:36:28 GMT
pragma:no-cache
server:nginx
x-request-id:253-23576671

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "254837009"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Malignant tumor of breast"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "254837009","display" : "Breast Cancer"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://snomed.info/sct#254837009 (\"Breast Cancer\")]\"\r\n0 0     : 0ms  : Check \"http://snomed.info/sct#254837009\"\r\n0 0     : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#855

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://clinicaltrials.gov","code":"NCT01234567","display":"NCT01234567"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:36:28 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:30951dee-40d6-43e3-ba5e-a1c6dc351a11
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:30951dee-40d6-43e3-ba5e-a1c6dc351a11
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NCT01234567"},{"name":"system","valueUri":"http://clinicaltrials.gov"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://clinicaltrials.gov was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://clinicaltrials.gov' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://clinicaltrials.gov"},{"name":"message","valueString":"A definition for CodeSystem 'http://clinicaltrials.gov' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://clinicaltrials.gov was not found"}]}

#856

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000017.11"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:36:31 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:5409a6a0-987d-4925-8778-64390adc4a51
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:5409a6a0-987d-4925-8778-64390adc4a51
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000017.11"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#857

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA30100-4"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL5323-2","name":"LOINCAnswersLL5323-2","title":"LOINC Answer Codes for LL5323-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL5323-2"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1167
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:36:33 GMT
last-modified:Fri, 30 Jan 2026 18:36:33 GMT
pragma:no-cache
server:nginx
x-request-id:253-23576739

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA30100-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "0-based interval counting"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA30100-4"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL5323-2 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL5323-2)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA30100-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA30100-4\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL5323-2) at CodeableConcept.coding[0]\r\n1328 1328: 1328ms : Filter \"LIST=LL5323-2\": Code \"LA30100-4\" found in http://loinc.org|2.81\r\n"}]}

#858

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA30100-4"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:884
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:36:34 GMT
last-modified:Fri, 30 Jan 2026 18:36:34 GMT
pragma:no-cache
server:nginx
x-request-id:253-23576764

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA30100-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "0-based interval counting"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA30100-4"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA30100-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA30100-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#859

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26418-6","display":"PCR"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL4048-6","name":"LOINCAnswersLL4048-6","title":"LOINC Answer Codes for LL4048-6","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL4048-6"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1166
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:36:35 GMT
last-modified:Fri, 30 Jan 2026 18:36:35 GMT
pragma:no-cache
server:nginx
x-request-id:253-23576782

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26418-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "PCR"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26418-6","display" : "PCR"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL4048-6 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL4048-6)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA26418-6 (\"PCR\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA26418-6\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL4048-6) at CodeableConcept.coding[0]\r\n1281 1281: 1281ms : Filter \"LIST=LL4048-6\": Code \"LA26418-6\" found in http://loinc.org|2.81\r\n"}]}

#860

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:11117","display":"SMN1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:36:36 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:6f29430c-77d7-4520-88d0-930bd96fd309
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:6f29430c-77d7-4520-88d0-930bd96fd309
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:11117"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#861

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:11117"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:36:36 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:be05b20c-b019-4b5f-abdb-9a8e4377754d
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x-request-id:be05b20c-b019-4b5f-abdb-9a8e4377754d
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:11117"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}]}

#862

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:11117","display":"SMN1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:36:37 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:8ab06d5b-0dde-4b57-901f-20f45f497b29
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:8ab06d5b-0dde-4b57-901f-20f45f497b29
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:11117"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#863

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000005.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:36:38 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:745bd105-36d8-46b5-ac68-cb37a888b905
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:745bd105-36d8-46b5-ac68-cb37a888b905
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000005.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#864

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26418-6","display":"PCR"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:883
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:36:39 GMT
last-modified:Fri, 30 Jan 2026 18:36:39 GMT
pragma:no-cache
server:nginx
x-request-id:253-23576837

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26418-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "PCR"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26418-6","display" : "PCR"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA26418-6 (\"PCR\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA26418-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#865

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26418-6","display":"PCR"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL4050-2","name":"LOINCAnswersLL4050-2","title":"LOINC Answer Codes for LL4050-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL4050-2"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2187
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:36:41 GMT
last-modified:Fri, 30 Jan 2026 18:36:41 GMT
pragma:no-cache
server:nginx
x-request-id:253-23576860

{"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://loinc.org/vs/LL4050-2'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26418-6","display" : "PCR"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA26418-6 ('PCR')' was not found in the value set 'http://loinc.org/vs/LL4050-2'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://loinc.org/vs/LL4050-2'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL4050-2 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL4050-2)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA26418-6 (\"PCR\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA26418-6\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL4050-2) at CodeableConcept.coding[0]\r\n1375 1375: 1375ms : Filter \"LIST=LL4050-2\": Code \"LA26418-6\" not found in http://loinc.org|2.81\r\n"}]}

#866

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"5262007","display":"Spinal muscular atrophy (disorder)"}],"text":"Spinal muscular atrophy (SMA)"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1136
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:36:41 GMT
last-modified:Fri, 30 Jan 2026 18:36:41 GMT
pragma:no-cache
server:nginx
x-request-id:253-23576882

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "5262007"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Spinal muscular atrophy"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "5262007","display" : "Spinal muscular atrophy (disorder)"}],"text" : "Spinal muscular atrophy (SMA)"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n15 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n15 0    : 0ms  : Prepare include: \"()\"\r\n15 0    : 0ms  : Validate \"[http://snomed.info/sct#5262007 (\"Spinal muscular atrophy (disorder)\")]\"\r\n15 0    : 0ms  : Check \"http://snomed.info/sct#5262007\"\r\n15 0    : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#867

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000001.10:g.86852621A>G","display":"NC_000001.10:g.86852621A>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:870
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:36:41 GMT
last-modified:Fri, 30 Jan 2026 18:36:41 GMT
pragma:no-cache
server:nginx
x-request-id:253-23576886

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000001.10:g.86852621A>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000001.10:g.86852621A>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000001.10:g.86852621A>G (\"NC_000001.10:g.86852621A>G\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000001.10:g.86852621A>G\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#868

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"69547-8","display":"Genomic Ref allele [ID]"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:935
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:36:43 GMT
last-modified:Fri, 30 Jan 2026 18:36:43 GMT
pragma:no-cache
server:nginx
x-request-id:253-23576892

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69547-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic ref allele [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "69547-8","display" : "Genomic Ref allele [ID]"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#69547-8 (\"Genomic Ref allele [ID]\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#69547-8\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#869

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"69551-0","display":"Genomic Alt allele [ID]"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:935
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:36:45 GMT
last-modified:Fri, 30 Jan 2026 18:36:45 GMT
pragma:no-cache
server:nginx
x-request-id:253-23576913

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69551-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic alt allele [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "69551-0","display" : "Genomic Alt allele [ID]"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#69551-0 (\"Genomic Alt allele [ID]\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#69551-0\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#870

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA30100-4","display":"0-based interval counting"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL5323-2","name":"LOINCAnswersLL5323-2","title":"LOINC Answer Codes for LL5323-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL5323-2"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1232
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:36:47 GMT
last-modified:Fri, 30 Jan 2026 18:36:47 GMT
pragma:no-cache
server:nginx
x-request-id:253-23576939

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA30100-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "0-based interval counting"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA30100-4","display" : "0-based interval counting"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL5323-2 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL5323-2)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA30100-4 (\"0-based interval counting\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA30100-4\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL5323-2) at CodeableConcept.coding[0]\r\n2016 2016: 2016ms : Filter \"LIST=LL5323-2\": Code \"LA30100-4\" found in http://loinc.org|2.81\r\n"}]}

#871

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA30100-4","display":"0-based interval counting"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:949
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:36:48 GMT
last-modified:Fri, 30 Jan 2026 18:36:48 GMT
pragma:no-cache
server:nginx
x-request-id:253-23576974

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA30100-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "0-based interval counting"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA30100-4","display" : "0-based interval counting"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA30100-4 (\"0-based interval counting\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA30100-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#872

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81254-5"}],"text":"Variant exact start-end"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:910
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:36:49 GMT
last-modified:Fri, 30 Jan 2026 18:36:49 GMT
pragma:no-cache
server:nginx
x-request-id:253-23576983

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81254-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic allele start-end"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81254-5"}],"text" : "Variant exact start-end"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81254-5 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81254-5\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#873

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"92821-8"}],"text":"Population allele frequency"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:921
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:36:51 GMT
last-modified:Fri, 30 Jan 2026 18:36:51 GMT
pragma:no-cache
server:nginx
x-request-id:253-23577007

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "92821-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic frequency in Population"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "92821-8"}],"text" : "Population allele frequency"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#92821-8 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#92821-8\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#874

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://example.org/pcingola.github.io/SnpEff/se_inputoutput/#impact-prediction","code":"HIGH","display":"High"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1821
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:36:51 GMT
last-modified:Fri, 30 Jan 2026 18:36:51 GMT
pragma:no-cache
server:nginx
x-request-id:253-23577033

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://example.org/pcingola.github.io/SnpEff/se_inputoutput/#impact-prediction"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://example.org/pcingola.github.io/SnpEff/se_inputoutput/#impact-prediction"},{"name" : "code","valueCode" : "HIGH"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://example.org/pcingola.github.io/SnpEff/se_inputoutput/#impact-prediction' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://example.org/pcingola.github.io/SnpEff/se_inputoutput/#impact-prediction' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n15 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n15 0    : 0ms  : Prepare include: \"()\"\r\n15 0    : 0ms  : Validate \"[http://example.org/pcingola.github.io/SnpEff/se_inputoutput/#impact-prediction#HIGH (\"High\")]\"\r\n15 0    : 0ms  : Check \"http://example.org/pcingola.github.io/SnpEff/se_inputoutput/#impact-prediction#HIGH\"\r\n15 0    : 0ms  : Didn't find CodeSystem \"http://example.org/pcingola.github.io/SnpEff/se_inputoutput/#impact-prediction\"\r\n"}]}

#875

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_001395525.1","display":"NM_001395525.1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:36:51 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:494e3b9b-38f3-4004-8568-467d9a23c761
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:494e3b9b-38f3-4004-8568-467d9a23c761
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NM_001395525.1"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#876

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001575","display":"splice_donor_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:36:52 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:d416b1a4-e7bf-4f25-985f-6d402f00c2e8
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:d416b1a4-e7bf-4f25-985f-6d402f00c2e8
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001575"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#877

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001627","display":"intron_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:36:52 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:5b892361-b4f3-42f3-8ecd-131e07e8ef86
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:5b892361-b4f3-42f3-8ecd-131e07e8ef86
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001627"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#878

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001575"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0001537"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:36:53 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:d110f694-7b6b-455c-9518-45fc80f22c99
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:d110f694-7b6b-455c-9518-45fc80f22c99
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001575"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}]}

#879

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001627"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0001537"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:36:53 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:c1477e10-1c40-4c1c-85e9-f45cfc38df9e
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x-request-id:c1477e10-1c40-4c1c-85e9-f45cfc38df9e
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001627"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}]}

#880

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001575","display":"splice_donor_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:36:54 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:a72691ec-02ea-48e8-8aa9-17b875a3cd26
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:a72691ec-02ea-48e8-8aa9-17b875a3cd26
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001575"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#881

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001627","display":"intron_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:36:55 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:c7d8cbc2-b40a-4d0a-ba88-8d1cfc1ccdba
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:c7d8cbc2-b40a-4d0a-ba88-8d1cfc1ccdba
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001627"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#882

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_001366781.1:c.90T>C","display":"NM_001366781.1:c.90T>C"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:850
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:36:55 GMT
last-modified:Fri, 30 Jan 2026 18:36:55 GMT
pragma:no-cache
server:nginx
x-request-id:253-23577100

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_001366781.1:c.90T>C"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_001366781.1:c.90T>C"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_001366781.1:c.90T>C (\"NM_001366781.1:c.90T>C\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_001366781.1:c.90T>C\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#883

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_001366781.1:c.90T>C"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1131
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:36:55 GMT
last-modified:Fri, 30 Jan 2026 18:36:55 GMT
pragma:no-cache
server:nginx
x-request-id:253-23577104

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_001366781.1:c.90T>C"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_001366781.1:c.90T>C"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_001366781.1:c.90T>C (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_001366781.1:c.90T>C\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n78 78   : 78ms : Code \"NM_001366781.1:c.90T>C\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#884

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_001366781.1","display":"NM_001366781.1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:36:55 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:861fa5d1-197f-4073-ab6f-b5b0186621da
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:861fa5d1-197f-4073-ab6f-b5b0186621da
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NM_001366781.1"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#885

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001819","display":"synonymous_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:36:56 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:e7e80102-21ce-4f02-9f7b-662a1aa445be
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:e7e80102-21ce-4f02-9f7b-662a1aa445be
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001819"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#886

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001819"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0001537"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:36:57 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:00c44aad-1022-4b41-a942-0841003bd4d4
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:00c44aad-1022-4b41-a942-0841003bd4d4
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001819"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}]}

#887

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001819","display":"synonymous_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:36:57 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:f7b582d2-1ba1-429b-b449-34e4c200fbed
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:f7b582d2-1ba1-429b-b449-34e4c200fbed
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001819"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#888

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_001395543.1:c.-171T>C","display":"NM_001395543.1:c.-171T>C"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:860
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:36:57 GMT
last-modified:Fri, 30 Jan 2026 18:36:57 GMT
pragma:no-cache
server:nginx
x-request-id:253-23577139

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_001395543.1:c.-171T>C"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_001395543.1:c.-171T>C"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_001395543.1:c.-171T>C (\"NM_001395543.1:c.-171T>C\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_001395543.1:c.-171T>C\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#889

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_001395543.1:c.-171T>C"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1141
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:36:58 GMT
last-modified:Fri, 30 Jan 2026 18:36:58 GMT
pragma:no-cache
server:nginx
x-request-id:253-23577142

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_001395543.1:c.-171T>C"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_001395543.1:c.-171T>C"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_001395543.1:c.-171T>C (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_001395543.1:c.-171T>C\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n78 78   : 78ms : Code \"NM_001395543.1:c.-171T>C\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#890

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_001395543.1","display":"NM_001395543.1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:36:58 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:3a1ebd2b-0650-43d0-a73f-665caeffb315
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x-request-id:3a1ebd2b-0650-43d0-a73f-665caeffb315
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NM_001395543.1"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#891

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001623","display":"5_prime_UTR_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:36:59 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:09c7b2bf-b9f6-46f0-843f-a4281a9cc032
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x-request-id:09c7b2bf-b9f6-46f0-843f-a4281a9cc032
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001623"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#892

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001623"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0001537"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:36:59 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:0cd2d2cf-5e4f-4d23-9325-a515af98da1a
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x-request-id:0cd2d2cf-5e4f-4d23-9325-a515af98da1a
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001623"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}]}

#893

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001623","display":"5_prime_UTR_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:00 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:90c17f60-551c-4882-948b-d01a317f158d
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x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:90c17f60-551c-4882-948b-d01a317f158d
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001623"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#894

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_001395544.1","display":"NM_001395544.1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:00 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:59495a89-1dae-4a8e-ad52-9bcb00a2aa8d
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:59495a89-1dae-4a8e-ad52-9bcb00a2aa8d
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NM_001395544.1"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#895

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001627","display":"intron_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:01 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:eb3c25d3-08b6-4d27-9a93-5465dc87b795
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x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:eb3c25d3-08b6-4d27-9a93-5465dc87b795
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001627"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#896

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001627"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0001537"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:01 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:425097d1-25a3-438b-8578-0bd0bad5d352
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x-request-id:425097d1-25a3-438b-8578-0bd0bad5d352
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001627"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}]}

#897

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001627","display":"intron_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:02 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:db609acd-6817-4c41-b27e-bbf65ff55e79
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x-request-id:db609acd-6817-4c41-b27e-bbf65ff55e79
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001627"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#898

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://purl.obolibrary.org/obo/mondo.owl","code":"MONDO:0009061","display":"cystic fibrosis"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:03 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:7c92bb56-9e87-4c4c-b108-c34be7e5164d
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:7c92bb56-9e87-4c4c-b108-c34be7e5164d
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"MONDO:0009061"},{"name":"system","valueUri":"http://purl.obolibrary.org/obo/mondo.owl"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://purl.obolibrary.org/obo/mondo.owl was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://purl.obolibrary.org/obo/mondo.owl' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://purl.obolibrary.org/obo/mondo.owl"},{"name":"message","valueString":"A definition for CodeSystem 'http://purl.obolibrary.org/obo/mondo.owl' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://purl.obolibrary.org/obo/mondo.owl was not found"}]}

#899

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://human-phenotype-ontology.org","code":"HP:0000007","display":"Autosomal recessive inheritance"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:03 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:16006d49-7fd2-4c43-b118-d5fabb9b52be
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:16006d49-7fd2-4c43-b118-d5fabb9b52be
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HP:0000007"},{"name":"system","valueUri":"http://human-phenotype-ontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://human-phenotype-ontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://human-phenotype-ontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://human-phenotype-ontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://human-phenotype-ontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://human-phenotype-ontology.org was not found"}]}

#900

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://human-phenotype-ontology.org","code":"HP:0000007"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/condition-inheritance-mode-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://human-phenotype-ontology.org","concept":[{"code":"HP:0000006","display":"Autosomal dominant inheritance"},{"code":"HP:0000007","display":"Autosomal recessive inheritance"},{"code":"HP:0001417","display":"X-linked inheritance"},{"code":"HP:0001419","display":"X-linked recessive inheritance"},{"code":"HP:0001423","display":"X-linked dominant inheritance"},{"code":"HP:0001426","display":"Multifactorial inheritance"},{"code":"HP:0001427","display":"Mitochondrial inheritance"},{"code":"HP:0001442","display":"Typified by somatic mosaicism"},{"code":"HP:0001450","display":"Y-linked inheritance"},{"code":"HP:0001470","display":"Sex-limited expression"},{"code":"HP:0003743","display":"Genetic anticipation"},{"code":"HP:0003745","display":"Sporadic"},{"code":"HP:0010983","display":"Oligogenic inheritance"},{"code":"HP:0012274","display":"Autosomal dominant inheritance with paternal imprinting"},{"code":"HP:0012275","display":"Autosomal dominant inheritance with maternal imprinting"},{"code":"HP:0025352","display":"Typically de novo"},{"code":"HP:0032113","display":"Semidominant inheritance"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:04 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:77f62288-f904-4a77-bc04-1004b8c7ed94
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:77f62288-f904-4a77-bc04-1004b8c7ed94
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HP:0000007"},{"name":"system","valueUri":"http://human-phenotype-ontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/condition-inheritance-mode-vs--0|4.0.0-cibuild' because the code system http://human-phenotype-ontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://human-phenotype-ontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://human-phenotype-ontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://human-phenotype-ontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/condition-inheritance-mode-vs--0|4.0.0-cibuild' because the code system http://human-phenotype-ontology.org was not found"}]}

#901

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://human-phenotype-ontology.org","code":"HP:0000007","display":"Autosomal recessive inheritance"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:04 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:f813b89a-2755-4f0e-85bb-30ae598457df
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:f813b89a-2755-4f0e-85bb-30ae598457df
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HP:0000007"},{"name":"system","valueUri":"http://human-phenotype-ontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://human-phenotype-ontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://human-phenotype-ontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://human-phenotype-ontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://human-phenotype-ontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://human-phenotype-ontology.org was not found"}]}

#902

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:11118","display":"SMN2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:032d77e7-908a-4a3f-86d2-d323a4b08e15
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:032d77e7-908a-4a3f-86d2-d323a4b08e15
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:11118"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#903

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:11118"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:05 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:2b2d04a7-f899-4cff-8bb0-3102aec0204b
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:2b2d04a7-f899-4cff-8bb0-3102aec0204b
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:11118"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}]}

#904

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:11118","display":"SMN2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:06 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:45687dfb-ad28-4d42-bbb2-1c537fd45330
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:45687dfb-ad28-4d42-bbb2-1c537fd45330
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:11118"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#905

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"92821-8","display":"Allelic frequency in Population"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:959
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:37:07 GMT
last-modified:Fri, 30 Jan 2026 18:37:07 GMT
pragma:no-cache
server:nginx
x-request-id:253-23577319

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "92821-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic frequency in Population"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "92821-8","display" : "Allelic frequency in Population"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#92821-8 (\"Allelic frequency in Population\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#92821-8\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#906

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26806-2","display":"GRCh38"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:892
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:37:09 GMT
last-modified:Fri, 30 Jan 2026 18:37:09 GMT
pragma:no-cache
server:nginx
x-request-id:253-23577354

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26806-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "GRCh38"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26806-2","display" : "GRCh38"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA26806-2 (\"GRCh38\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA26806-2\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#907

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001483","display":"SNV"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:09 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:04dafc21-b14b-4641-99f3-fe48b3376034
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:04dafc21-b14b-4641-99f3-fe48b3376034
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001483"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#908

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0002007","display":"MNV"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:10 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:915b033b-4e06-4947-be82-f279b0668b32
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:915b033b-4e06-4947-be82-f279b0668b32
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0002007"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#909

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:1000032","display":"delins"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:10 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:528f3738-2a31-4777-8c61-ba4bede8de0e
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:528f3738-2a31-4777-8c61-ba4bede8de0e
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:1000032"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#910

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001019","display":"copy_number_variation"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:11 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:3e6cfd6e-0934-4fbe-a04b-fb429dddcff3
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:3e6cfd6e-0934-4fbe-a04b-fb429dddcff3
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001019"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#911

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"53037-8"}],"text":"Genetic variation clinical significance"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:947
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:37:12 GMT
last-modified:Fri, 30 Jan 2026 18:37:12 GMT
pragma:no-cache
server:nginx
x-request-id:253-23577420

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "53037-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic variation clinical significance [Imp]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "53037-8"}],"text" : "Genetic variation clinical significance"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#53037-8 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#53037-8\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#912

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81259-4"}],"text":"Predicted phenotype"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:902
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:37:14 GMT
last-modified:Fri, 30 Jan 2026 18:37:14 GMT
pragma:no-cache
server:nginx
x-request-id:253-23577447

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81259-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Associated phenotype"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81259-4"}],"text" : "Predicted phenotype"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81259-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81259-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#913

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"405501007","display":"Malignant hyperthermia"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1078
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:37:14 GMT
last-modified:Fri, 30 Jan 2026 18:37:14 GMT
pragma:no-cache
server:nginx
x-request-id:253-23577471

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "405501007"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Malignant hyperthermia"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "405501007","display" : "Malignant hyperthermia"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://snomed.info/sct#405501007 (\"Malignant hyperthermia\")]\"\r\n0 0     : 0ms  : Check \"http://snomed.info/sct#405501007\"\r\n0 0     : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#914

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48002-0","display":"Genomic source class [Type]"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:947
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:37:16 GMT
last-modified:Fri, 30 Jan 2026 18:37:16 GMT
pragma:no-cache
server:nginx
x-request-id:253-23577474

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48002-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic source class [Type]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48002-0","display" : "Genomic source class [Type]"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48002-0 (\"Genomic source class [Type]\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48002-0\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#915

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000019.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:16 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:1f8da52a-5144-4e94-9738-93655af9d400
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:1f8da52a-5144-4e94-9738-93655af9d400
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000019.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#916

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81254-5"}],"text":"Genomic allele start-end"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:911
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:37:18 GMT
last-modified:Fri, 30 Jan 2026 18:37:18 GMT
pragma:no-cache
server:nginx
x-request-id:253-23577514

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81254-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic allele start-end"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81254-5"}],"text" : "Genomic allele start-end"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81254-5 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81254-5\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#917

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"CYP2D6_*1/*1","display":"CYP2D6 *1/*1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:18 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:9090a060-893b-4cf4-8209-e9528df7b7d7
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:9090a060-893b-4cf4-8209-e9528df7b7d7
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"CYP2D6_*1/*1"},{"name":"system","valueUri":"http://www.pharmvar.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.pharmvar.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.pharmvar.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.pharmvar.org was not found"}]}

#918

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"CYP2C19_*1/*2","display":"CYP2C19 *1/*2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:19 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:d68a16a9-8715-49ad-b73a-5ba051e1c901
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:d68a16a9-8715-49ad-b73a-5ba051e1c901
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"CYP2C19_*1/*2"},{"name":"system","valueUri":"http://www.pharmvar.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.pharmvar.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.pharmvar.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.pharmvar.org was not found"}]}

#919

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://glstring.org","version":"1.0","code":"hla#3.33.0#HLA-A*02:69+HLA-A*23:30|HLA-A*02:302+HLA-A*23:26/HLA-A*23:39","display":"hla#3.33.0#HLA-A*02:69+HLA-A*23:30|HLA-A*02:302+HLA-A*23:26/HLA-A*23:39"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1858
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:37:19 GMT
last-modified:Fri, 30 Jan 2026 18:37:19 GMT
pragma:no-cache
server:nginx
x-request-id:253-23577558

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://glstring.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://glstring.org"},{"name" : "code","valueCode" : "hla#3.33.0#HLA-A*02:69+HLA-A*23:30|HLA-A*02:302+HLA-A*23:26/HLA-A*23:39"},{"name" : "version","valueString" : "1.0"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://glstring.org|1.0#hla#3.33.0#HLA-A*02:69+HLA-A*23:30|HLA-A*02:302+HLA-A*23:26/HLA-A*23:39 (\"hla#3.33.0#HLA-A*02:69+HLA-A*23:30|HLA-A*02:302+HLA-A*23:26/HLA-A*23:39\")]\"\r\n0 0     : 0ms  : Check \"http://glstring.org|1.0#hla#3.33.0#HLA-A*02:69+HLA-A*23:30|HLA-A*02:302+HLA-A*23:26/HLA-A*23:39\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://glstring.org|1.0\"\r\n"}]}

#920

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000005.9"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:19 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:310dc01c-2eb0-4561-95f0-d43d07a2f6d6
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:310dc01c-2eb0-4561-95f0-d43d07a2f6d6
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000005.9"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#921

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA9633-4","display":"present"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:891
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:37:20 GMT
last-modified:Fri, 30 Jan 2026 18:37:20 GMT
pragma:no-cache
server:nginx
x-request-id:253-23577571

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA9633-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Present"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA9633-4","display" : "present"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA9633-4 (\"present\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA9633-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#922

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48019-4","display":"DNA Change Type"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:911
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:37:22 GMT
last-modified:Fri, 30 Jan 2026 18:37:22 GMT
pragma:no-cache
server:nginx
x-request-id:253-23577584

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48019-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "DNA change type"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48019-4","display" : "DNA Change Type"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48019-4 (\"DNA Change Type\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48019-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#923

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000007.13"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:22 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:e0e7a40a-4831-4a03-b0f1-e473acbae8a6
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:e0e7a40a-4831-4a03-b0f1-e473acbae8a6
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000007.13"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#924

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48002-0","display":"Genomic Source Class"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:933
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:37:24 GMT
last-modified:Fri, 30 Jan 2026 18:37:24 GMT
pragma:no-cache
server:nginx
x-request-id:253-23577613

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48002-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic source class [Type]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48002-0","display" : "Genomic Source Class"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48002-0 (\"Genomic Source Class\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48002-0\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#925

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81302-2"}],"text":"Variant inner start and end"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:928
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:37:25 GMT
last-modified:Fri, 30 Jan 2026 18:37:25 GMT
pragma:no-cache
server:nginx
x-request-id:253-23577635

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81302-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Structural variant inner start and end"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81302-2"}],"text" : "Variant inner start and end"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81302-2 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81302-2\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#926

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA9633-4","display":"present"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL1971-2","name":"LOINCAnswersLL1971-2","title":"LOINC Answer Codes for LL1971-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL1971-2"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1173
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:37:27 GMT
last-modified:Fri, 30 Jan 2026 18:37:27 GMT
pragma:no-cache
server:nginx
x-request-id:253-23577659

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA9633-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Present"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA9633-4","display" : "present"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL1971-2 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL1971-2)\"\r\n16 16   : 16ms : CodeSystem found: \"http://loinc.org|2.81\"\r\n16 0    : 16ms : Validate \"[http://loinc.org#LA9633-4 (\"present\")]\"\r\n16 0    : 16ms : Check \"http://loinc.org#LA9633-4\"\r\n16 0    : 16ms : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0    : 16ms : check code in (http://loinc.org)(LIST=LL1971-2) at CodeableConcept.coding[0]\r\n1375 1359: 1375ms : Filter \"LIST=LL1971-2\": Code \"LA9633-4\" found in http://loinc.org|2.81\r\n"}]}

#927

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000007.14"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:27 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:85003e0b-089e-4acc-8ff9-fccb21c69faf
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:85003e0b-089e-4acc-8ff9-fccb21c69faf
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000007.14"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#928

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"82155-3","display":"Genomic Structural Variant copy Number"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:980
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:37:29 GMT
last-modified:Fri, 30 Jan 2026 18:37:29 GMT
pragma:no-cache
server:nginx
x-request-id:253-23577688

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82155-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic structural variant copy number"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "82155-3","display" : "Genomic Structural Variant copy Number"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#82155-3 (\"Genomic Structural Variant copy Number\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#82155-3\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#929

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://www.nlm.nih.gov/research/umls/rxnorm","code":"480167","display":"Lapatinib"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1020
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:37:29 GMT
last-modified:Fri, 30 Jan 2026 18:37:29 GMT
pragma:no-cache
server:nginx
x-request-id:253-23577708

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://www.nlm.nih.gov/research/umls/rxnorm"},{"name" : "code","valueCode" : "480167"},{"name" : "version","valueString" : "??"},{"name" : "display","valueString" : "lapatinib"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://www.nlm.nih.gov/research/umls/rxnorm","code" : "480167","display" : "Lapatinib"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.nlm.nih.gov/research/umls/rxnorm#480167 (\"Lapatinib\")]\"\r\n0 0     : 0ms  : Check \"http://www.nlm.nih.gov/research/umls/rxnorm#480167\"\r\n0 0     : 0ms  : Using CodeSystem \"http://www.nlm.nih.gov/research/umls/rxnorm|??\" (content = complete)\r\n"}]}

#930

GET https://tx.fhir.org/r4/CodeSystem?_format=json&url=urn%3Aietf%3Abcp%3A47 HTTP/1.0
User-Agent: hapi-fhir-tooling-client
Accept: application/fhir+json; fhirVersion=4.0

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:233
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:37:29 GMT
pragma:no-cache
server:nginx
x-request-id:253-23577712

{"resourceType" : "Bundle","id" : "fa95733f-2118-4ae9-82ac-32490deee0","meta" : {"lastUpdated" : "2026-01-30T18:37:29.316Z"},"type" : "searchset","total" : 0,"link" : [{"relation" : "self","url" : "CodeSystem?&url=urn:ietf:bcp:47"}]}

#931

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"urn:ietf:bcp:47","code":"en-US","display":"English (Region=United States)"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:733
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:37:29 GMT
last-modified:Fri, 30 Jan 2026 18:37:29 GMT
pragma:no-cache
server:nginx
x-request-id:253-23577715

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "urn:ietf:bcp:47"},{"name" : "code","valueCode" : "en-US"},{"name" : "display","valueString" : "English (Region=United States)"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[urn:ietf:bcp:47#en-US (\"English (Region=United States)\")]\"\r\n0 0     : 0ms  : Check \"urn:ietf:bcp:47#en-US\"\r\n0 0     : 0ms  : Using CodeSystem \"urn:ietf:bcp:47|\" (content = complete)\r\n"}]}

#932

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"urn:ietf:bcp:47","code":"en-US"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/ValueSet/languages--0","version":"4.0.1","status":"active","compose":{"include":[{"system":"urn:ietf:bcp:47","concept":[{"code":"ar","display":"Arabic","designation":[{"language":"da","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Arabisk"},{"language":"en","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Arabic"},{"language":"nl","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Arabisch"}]},{"code":"bn","display":"Bengali","designation":[{"language":"en","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Bengali"},{"language":"nl","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Bengaals"},{"language":"ru","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Бенгальский"},{"language":"zh","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"孟加拉语"},{"language":"de","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Bengalisch"},{"language":"da","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Bengalsk"}]},{"code":"cs","display":"Czech","designation":[{"language":"en","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Czech"},{"language":"nl","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Tsjechisch"},{"language":"ru","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Чешский"},{"language":"zh","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"捷克语"},{"language":"de","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Tschechisch"},{"language":"da","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Tjekkisk"}]},{"code":"da","display":"Danish","designation":[{"language":"en","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Danish"},{"language":"nl","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Deens"},{"language":"ru","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Датский"},{"language":"zh","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"丹麦语"},{"language":"de","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Dänisch"},{"language":"da","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Dansk"}]},{"code":"de","display":"German","designation":[{"language":"en","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"German"},{"language":"nl","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Duits"},{"language":"ru","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Немецкий"},{"language":"zh","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"德语"},{"language":"de","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Deutsch"},{"language":"da","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Tysk"}]},{"code":"de-AT","display":"German (Austria)","designation":[{"language":"en","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"German (Austria)"},{"language":"nl","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Duits (Oostenrijk)"},{"language":"ru","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Немецкий (Австрия)"},{"language":"zh","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"德语 （奥地利）"},{"language":"de","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Deutsch (Österreich)"},{"language":"da","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Tysk (Østrig"}]},{"code":"de-CH","display":"German (Switzerland)","designation":[{"language":"en","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"German (Switzerland)"},{"language":"nl","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Duits (Zwitserland)"},{"language":"ru","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Немецкий (Швейцария)"},{"language":"zh","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"德语 （瑞士）"},{"language":"de","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Deutsch (Schweiz)"},{"language":"da","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Tysk (Schweiz)"}]},{"code":"de-DE","display":"German (Germany)","designation":[{"language":"en","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"German (Germany)"},{"language":"nl","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Duits (Duitsland)"},{"language":"ru","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Немецкий (Германия)"},{"language":"zh","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"德语 （德国）"},{"language":"de","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Deutsch (Deutschland)"},{"language":"da","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Tysk (Tyskland)"}]},{"code":"el","display":"Greek","designation":[{"language":"en","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Greek"},{"language":"nl","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Grieks"},{"language":"ru","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Греческий"},{"language":"zh","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"希腊语"},{"language":"de","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Griechisch"},{"language":"da","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Græsk"}]},{"code":"en","display":"English","designation":[{"language":"en","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"English"},{"language":"nl","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Engels"},{"language":"ru","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Английский"},{"language":"zh","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"英语"},{"language":"de","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Englisch"},{"language":"da","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Engelsk"}]},{"code":"en-AU","display":"English 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(Canada)","designation":[{"language":"en","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"English (Canada)"},{"language":"nl","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Engels (Canada)"},{"language":"ru","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Английский (Канада)"},{"language":"zh","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"英语 （加拿大）"},{"language":"de","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Englisch (Kanada)"},{"language":"da","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Engelsk (Canada)"}]},{"code":"en-GB","display":"English (Great Britain)","designation":[{"language":"en","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"English (Great Britain)"},{"language":"nl","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Engels (Groot Brittannië)"},{"language":"ru","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Английский (Великобритания)"},{"language":"zh","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"英语 （英国）"},{"language":"de","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Englisch (Großbritannien)"},{"language":"da","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Engelsk (Storbritannien)"}]},{"code":"en-IN","display":"English 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(Russia)","designation":[{"language":"en","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Russian (Russia)"},{"language":"nl","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Russisch (Rusland)"},{"language":"ru","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Русский (Россия)"},{"language":"zh","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"俄语 （俄罗斯）"},{"language":"de","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Russisch (Russland)"},{"language":"da","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Russisk (Rusland)"}]},{"code":"sr","display":"Serbian","designation":[{"language":"en","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Serbian"},{"language":"nl","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Servisch"},{"language":"ru","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Сербский"},{"language":"zh","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"塞尔维亚语"},{"language":"de","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Serbisch"},{"language":"da","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Serbisk"}]},{"code":"sr-RS","display":"Serbian (Serbia)","designation":[{"language":"en","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Serbian (Serbia)"},{"language":"nl","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Servisch (Servië)"},{"language":"ru","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Сербский (Сербия)"},{"language":"zh","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"塞尔维亚语 （塞尔维亚）"},{"language":"de","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Serbisch (Serbien)"},{"language":"da","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Serbisk (Serbien)"}]},{"code":"sv","display":"Swedish","designation":[{"language":"en","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Swedish"},{"language":"nl","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Zweeds"},{"language":"ru","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Шведский"},{"language":"zh","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"瑞典语"},{"language":"de","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Schwedisch"},{"language":"da","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Svensk"}]},{"code":"sv-SE","display":"Swedish (Sweden)","designation":[{"language":"en","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Swedish (Sweden)"},{"language":"nl","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Zweeds (Zweden)"},{"language":"ru","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Шведский (Швеция)"},{"language":"zh","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"瑞典语 （瑞典）"},{"language":"de","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Schwedisch (Schweden)"},{"language":"da","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Svensk (Sverige)"}]},{"code":"te","display":"Telegu","designation":[{"language":"en","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Telegu"},{"language":"nl","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Teloegoe"},{"language":"ru","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Телугу"},{"language":"zh","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"泰卢固语"},{"language":"de","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Telugu"},{"language":"da","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Telugu"}]},{"code":"zh","display":"Chinese","designation":[{"language":"en","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Chinese"},{"language":"nl","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Chinees"},{"language":"ru","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Kитайский"},{"language":"zh","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"中文"},{"language":"de","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Chinesisch"},{"language":"da","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Kinesisk"}]},{"code":"zh-CN","display":"Chinese (China)","designation":[{"language":"en","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Chinese (China)"},{"language":"nl","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Chinees (China)"},{"language":"ru","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Kитайский (Китай)"},{"language":"zh","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"中文 （中国）"},{"language":"de","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Chinesisch (China)"},{"language":"da","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Kinesisk (Kina)"}]},{"code":"zh-HK","display":"Chinese (Hong Kong)","designation":[{"language":"en","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Chinese (Hong Kong)"},{"language":"nl","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Chinees (Hong Kong)"},{"language":"ru","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Kитайский (Гонконг)"},{"language":"zh","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"中文 （香港特别行政区）"},{"language":"de","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Chinesisch (Hong Kong)"},{"language":"da","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Kinesisk (Hong Kong)"}]},{"code":"zh-SG","display":"Chinese (Singapore)","designation":[{"language":"en","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Chinese (Singapore)"},{"language":"nl","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Chinees (Singapore)"},{"language":"ru","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Kитайский (Сингапур)"},{"language":"zh","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"中文 （新加坡）"},{"language":"de","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Chinesisch (Singapur)"},{"language":"da","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Kinesisk (Singapore)"}]},{"code":"zh-TW","display":"Chinese (Taiwan)","designation":[{"language":"en","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Chinese (Taiwan)"},{"language":"nl","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Chinees (Taiwan)"},{"language":"ru","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Kитайский (Тайвань)"},{"language":"zh","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"中文 （台湾）"},{"language":"de","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Chinesisch (Taiwan)"},{"language":"da","use":{"system":"http://terminology.hl7.org/CodeSystem/designation-usage","code":"display"},"value":"Kinesisk (Taiwan)"}]}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1421
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:37:29 GMT
last-modified:Fri, 30 Jan 2026 18:37:29 GMT
pragma:no-cache
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x-request-id:253-23577716

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "urn:ietf:bcp:47"},{"name" : "code","valueCode" : "en-US"},{"name" : "display","valueString" : "English (United States)"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n78 78   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/languages--0|4.0.1 for validation purposes\r\n78 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n78 0    : 0ms  : Prepare include: \"(urn:ietf:bcp:47)(ar,bn,cs,da,de,de-AT,de-CH,de-DE,el,en,en-AU,en-CA,en-GB,en-IN,en-NZ,en-SG,en-US,es,es-AR,es-ES,es-UY,fi,fr,fr-BE,fr-CH,fr-FR,fy,fy-NL,hi,hr,it,it-CH,it-IT,ja,ko,nl,nl-BE,nl-NL,no,no-NO,pa,pl,pt,pt-BR,ru,ru-RU,sr,sr-RS,sv,sv-SE,te,zh,zh-CN,zh-HK,zh-SG,zh-TW)\"\r\n78 0    : 0ms  : CodeSystem found: \"urn:ietf:bcp:47|\"\r\n78 0    : 0ms  : Validate \"[urn:ietf:bcp:47#en-US (\"\")]\"\r\n78 0    : 0ms  : Check \"urn:ietf:bcp:47#en-US\"\r\n78 0    : 0ms  : CodeSystem found: urn:ietf:bcp:47| for urn:ietf:bcp:47\r\n78 0    : 0ms  : check code in (urn:ietf:bcp:47)(ar,bn,cs,da,de,de-AT,de-CH,de-DE,el,en,en-AU,en-CA,en-GB,en-IN,en-NZ,en-SG,en-US,es,es-AR,es-ES,es-UY,fi,fr,fr-BE,fr-CH,fr-FR,fy,fy-NL,hi,hr,it,it-CH,it-IT,ja,ko,nl,nl-BE,nl-NL,no,no-NO,pa,pl,pt,pt-BR,ru,ru-RU,sr,sr-RS,sv,sv-SE,te,zh,zh-CN,zh-HK,zh-SG,zh-TW) at Coding\r\n78 0    : 0ms  : Code \"en-US\" found in urn:ietf:bcp:47|\r\n"}]}

#933

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26806-2","display":"GRCh38"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL1040-6","name":"LOINCAnswersLL1040-6","title":"LOINC Answer Codes for LL1040-6","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL1040-6"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1175
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:37:31 GMT
last-modified:Fri, 30 Jan 2026 18:37:31 GMT
pragma:no-cache
server:nginx
x-request-id:253-23577720

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26806-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "GRCh38"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26806-2","display" : "GRCh38"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL1040-6 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL1040-6)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA26806-2 (\"GRCh38\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA26806-2\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL1040-6) at CodeableConcept.coding[0]\r\n2031 2031: 2031ms : Filter \"LIST=LL1040-6\": Code \"LA26806-2\" found in http://loinc.org|2.81\r\n"}]}

#934

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"443968007","display":"Sequencing of entire coding region of gene (procedure)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1174
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:37:31 GMT
last-modified:Fri, 30 Jan 2026 18:37:31 GMT
pragma:no-cache
server:nginx
x-request-id:253-23577753

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "443968007"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Sequencing of entire coding region of gene (procedure)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "443968007","display" : "Sequencing of entire coding region of gene (procedure)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://snomed.info/sct#443968007 (\"Sequencing of entire coding region of gene (procedure)\")]\"\r\n0 0     : 0ms  : Check \"http://snomed.info/sct#443968007\"\r\n0 0     : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#935

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:76","display":"ABL1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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date:Fri, 30 Jan 2026 18:37:32 GMT
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x-content-type-options:nosniff
x-correlation-id:e8f83bd8-5aec-4d9c-af20-526184daac01
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x-request-id:e8f83bd8-5aec-4d9c-af20-526184daac01
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:76"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#936

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:76","display":"ABL1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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date:Fri, 30 Jan 2026 18:37:32 GMT
server:nginx
vary:Origin
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vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
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x-request-id:67e34c99-8062-449d-b65a-367f70da37e8
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{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:76"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#937

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:76"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:33 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:d731d516-8d77-4b4d-a922-dccd60597f94
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:d731d516-8d77-4b4d-a922-dccd60597f94
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:76"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}]}

#938

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:427","display":"ALK"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:33 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:fa712623-c32c-4d8e-90a6-11da9ff90bc4
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:fa712623-c32c-4d8e-90a6-11da9ff90bc4
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:427"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#939

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:427","display":"ALK"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:34 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:4c2397f2-a711-4962-9b6a-e37a07b9ff5b
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:4c2397f2-a711-4962-9b6a-e37a07b9ff5b
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:427"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#940

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:427"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:34 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:8dbb1126-ba54-45d7-b30c-3ecd5a588551
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:8dbb1126-ba54-45d7-b30c-3ecd5a588551
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:427"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}]}

#941

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:583","display":"APC"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:35 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:063e96cf-d535-48e6-9afb-025248d35ee9
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:063e96cf-d535-48e6-9afb-025248d35ee9
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:583"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#942

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:583","display":"APC"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:35 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:8678abda-22ce-400a-b9c7-7b97e4627c3f
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:8678abda-22ce-400a-b9c7-7b97e4627c3f
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:583"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.genenames.org was not found"}]}

#943

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:583"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:36 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:980414b6-e19b-46f8-ae2b-902e628d6e92
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:980414b6-e19b-46f8-ae2b-902e628d6e92
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"HGNC:583"},{"name":"system","valueUri":"http://www.genenames.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.genenames.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-cibuild' because the code system http://www.genenames.org was not found"}]}

#944

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001483","display":"SNV"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:37 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:57ed2fe7-16cb-46af-9a53-bf7cff86602c
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:57ed2fe7-16cb-46af-9a53-bf7cff86602c
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001483"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#945

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001483"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genomic-study-change-type-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0002072"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:37 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:41a19eeb-a118-4ff8-8910-9b6f87aaa1a9
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:41a19eeb-a118-4ff8-8910-9b6f87aaa1a9
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001483"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genomic-study-change-type-vs--0|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genomic-study-change-type-vs--0|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}]}

#946

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001483"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genomic-study-change-type-vs--1","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0001060"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:38 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:a7db9453-f9b6-4e86-8263-cfa39fa16054
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:a7db9453-f9b6-4e86-8263-cfa39fa16054
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001483"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genomic-study-change-type-vs--1|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genomic-study-change-type-vs--1|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}]}

#947

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0002007","display":"MNV"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:38 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:1cb7efd7-be20-417c-802f-f18cdbe6ce8e
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:1cb7efd7-be20-417c-802f-f18cdbe6ce8e
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0002007"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#948

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0002007"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genomic-study-change-type-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0002072"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:39 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:0324daa0-670c-46c7-b820-f2273eaf4fd1
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:0324daa0-670c-46c7-b820-f2273eaf4fd1
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0002007"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genomic-study-change-type-vs--0|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genomic-study-change-type-vs--0|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}]}

#949

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0002007"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genomic-study-change-type-vs--1","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0001060"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:39 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:6759370a-972a-40d9-b6b9-98dc936d475c
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:6759370a-972a-40d9-b6b9-98dc936d475c
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0002007"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genomic-study-change-type-vs--1|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genomic-study-change-type-vs--1|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}]}

#950

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0002007","display":"MNV"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:40 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:9bd86355-7272-4303-9901-4f743f3fd318
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:9bd86355-7272-4303-9901-4f743f3fd318
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0002007"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#951

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:1000032","display":"delins"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:40 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:1ab5580f-a680-4f5a-b835-ce99be560af4
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:1ab5580f-a680-4f5a-b835-ce99be560af4
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:1000032"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#952

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:1000032"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genomic-study-change-type-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0002072"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:41 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:4da35442-0e8d-4be6-a405-d3fdb60afb67
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:4da35442-0e8d-4be6-a405-d3fdb60afb67
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:1000032"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genomic-study-change-type-vs--0|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genomic-study-change-type-vs--0|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}]}

#953

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:1000032"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genomic-study-change-type-vs--1","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0001060"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:41 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:68a049d0-97c7-42bd-86a7-9004b284ae63
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:68a049d0-97c7-42bd-86a7-9004b284ae63
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:1000032"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genomic-study-change-type-vs--1|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genomic-study-change-type-vs--1|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}]}

#954

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:1000032","display":"delins"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:42 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:92066304-4b1c-484b-8e16-8b7ba1ddb4bc
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:92066304-4b1c-484b-8e16-8b7ba1ddb4bc
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:1000032"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#955

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001019","display":"CNV"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:42 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:e87a9f9c-ec77-43d9-8950-aaa038e30d0f
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:e87a9f9c-ec77-43d9-8950-aaa038e30d0f
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001019"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#956

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001019"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genomic-study-change-type-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0002072"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:43 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:a61f502e-b057-4121-9e5c-7121bfeb9e84
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:a61f502e-b057-4121-9e5c-7121bfeb9e84
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001019"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genomic-study-change-type-vs--0|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genomic-study-change-type-vs--0|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}]}

#957

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001019"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genomic-study-change-type-vs--1","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0001060"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:43 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:06b66cc9-8fa6-401e-bd4a-de7952e71a84
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:06b66cc9-8fa6-401e-bd4a-de7952e71a84
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001019"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genomic-study-change-type-vs--1|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genomic-study-change-type-vs--1|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}]}

#958

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001019","display":"CNV"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:44 GMT
server:nginx
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vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:09eae488-2f2c-455a-a1b4-94eaf6ae04c5
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:09eae488-2f2c-455a-a1b4-94eaf6ae04c5
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001019"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#959

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001565","display":"gene_fusion"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:45 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:eb22f32b-071d-4a2a-8ddb-dcfdd1c8f83e
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:eb22f32b-071d-4a2a-8ddb-dcfdd1c8f83e
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001565"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#960

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001565"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genomic-study-change-type-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0002072"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:45 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:b1c1b420-34ec-4e9d-af88-8a57225bc9b9
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:b1c1b420-34ec-4e9d-af88-8a57225bc9b9
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001565"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genomic-study-change-type-vs--0|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genomic-study-change-type-vs--0|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}]}

#961

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001565"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genomic-study-change-type-vs--1","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0001060"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:46 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:04d03f0e-724e-47da-a4d9-3dd15ea2a72c
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:04d03f0e-724e-47da-a4d9-3dd15ea2a72c
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001565"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genomic-study-change-type-vs--1|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genomic-study-change-type-vs--1|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}]}

#962

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001565","display":"gene_fusion"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:46 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:03708235-cb28-4ada-8b34-e7b97870e08e
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:03708235-cb28-4ada-8b34-e7b97870e08e
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001565"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#963

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001576","display":"transcript_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:47 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:1f3cbe6e-9e3c-49a4-936b-060722a2c72a
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:1f3cbe6e-9e3c-49a4-936b-060722a2c72a
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001576"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#964

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001576"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genomic-study-change-type-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0002072"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:47 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:2288e8f1-dd30-4279-84d0-7dcc0b0f2099
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:2288e8f1-dd30-4279-84d0-7dcc0b0f2099
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001576"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genomic-study-change-type-vs--0|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genomic-study-change-type-vs--0|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}]}

#965

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001576"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genomic-study-change-type-vs--1","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0001060"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:48 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:77a43a56-c556-449f-bcdd-40f4bca958a5
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:77a43a56-c556-449f-bcdd-40f4bca958a5
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001576"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genomic-study-change-type-vs--1|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genomic-study-change-type-vs--1|4.0.0-cibuild' because the code system http://www.sequenceontology.org was not found"}]}

#966

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001576","display":"transcript_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:37:48 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:a99f0ef7-b50c-4886-af15-f0f559d82951
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:a99f0ef7-b50c-4886-af15-f0f559d82951
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001576"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#967

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"309529002","display":"Lung mass (finding)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1059
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:37:49 GMT
last-modified:Fri, 30 Jan 2026 18:37:49 GMT
pragma:no-cache
server:nginx
x-request-id:253-23578014

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "309529002"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Lung mass"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "309529002","display" : "Lung mass (finding)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://snomed.info/sct#309529002 (\"Lung mass (finding)\")]\"\r\n0 0     : 0ms  : Check \"http://snomed.info/sct#309529002\"\r\n0 0     : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#968

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"424993006","display":"Adenocarcinoma of lung, stage IV (disorder)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1130
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:37:49 GMT
last-modified:Fri, 30 Jan 2026 18:37:49 GMT
pragma:no-cache
server:nginx
x-request-id:253-23578017

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "424993006"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Adenocarcinoma of lung, stage IV"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "424993006","display" : "Adenocarcinoma of lung, stage IV (disorder)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://snomed.info/sct#424993006 (\"Adenocarcinoma of lung, stage IV (disorder)\")]\"\r\n0 0     : 0ms  : Check \"http://snomed.info/sct#424993006\"\r\n0 0     : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#969

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://unitsofmeasure.org","code":"a"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:748
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:37:49 GMT
last-modified:Fri, 30 Jan 2026 18:37:49 GMT
pragma:no-cache
server:nginx
x-request-id:253-23578018

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://unitsofmeasure.org"},{"name" : "code","valueCode" : "a"},{"name" : "version","valueString" : "2.2"},{"name" : "display","valueString" : "a"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://unitsofmeasure.org#a (\"\")]\"\r\n0 0     : 0ms  : Check \"http://unitsofmeasure.org#a\"\r\n16 16   : 16ms : Using CodeSystem \"http://unitsofmeasure.org|2.2\" (content = complete)\r\n"}]}

#970

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"94231-8","display":"G6PD gene full mutation analysis in Blood or Tissue by Sequencing"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1061
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:37:51 GMT
last-modified:Fri, 30 Jan 2026 18:37:51 GMT
pragma:no-cache
server:nginx
x-request-id:253-23578023

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "94231-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "G6PD gene full mutation analysis in Blood or Tissue by Sequencing"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "94231-8","display" : "G6PD gene full mutation analysis in Blood or Tissue by Sequencing"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#94231-8 (\"G6PD gene full mutation analysis in Blood or Tissue by Sequencing\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#94231-8\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#971

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://example.org/hgsc.bcm.edu/lab-test-codes/","code":"emerge-seq-ngs-pnl"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1642
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:37:51 GMT
last-modified:Fri, 30 Jan 2026 18:37:51 GMT
pragma:no-cache
server:nginx
x-request-id:253-23578041

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://example.org/hgsc.bcm.edu/lab-test-codes/"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://example.org/hgsc.bcm.edu/lab-test-codes/"},{"name" : "code","valueCode" : "emerge-seq-ngs-pnl"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://example.org/hgsc.bcm.edu/lab-test-codes/' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://example.org/hgsc.bcm.edu/lab-test-codes/' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://example.org/hgsc.bcm.edu/lab-test-codes/#emerge-seq-ngs-pnl (\"\")]\"\r\n0 0     : 0ms  : Check \"http://example.org/hgsc.bcm.edu/lab-test-codes/#emerge-seq-ngs-pnl\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://example.org/hgsc.bcm.edu/lab-test-codes/\"\r\n"}]}

#972

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"405825005","display":"Molecular genetic test (procedure)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1114
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:37:51 GMT
last-modified:Fri, 30 Jan 2026 18:37:51 GMT
pragma:no-cache
server:nginx
x-request-id:253-23578043

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "405825005"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Molecular genetic test (procedure)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "405825005","display" : "Molecular genetic test (procedure)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://snomed.info/sct#405825005 (\"Molecular genetic test (procedure)\")]\"\r\n0 0     : 0ms  : Check \"http://snomed.info/sct#405825005\"\r\n0 0     : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#973

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"108252007","display":"Laboratory procedure"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1072
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:37:51 GMT
last-modified:Fri, 30 Jan 2026 18:37:51 GMT
pragma:no-cache
server:nginx
x-request-id:253-23578045

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "108252007"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Laboratory procedure"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "108252007","display" : "Laboratory procedure"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://snomed.info/sct#108252007 (\"Laboratory procedure\")]\"\r\n0 0     : 0ms  : Check \"http://snomed.info/sct#108252007\"\r\n0 0     : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#974

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"13298-5","display":"HLA-A [Type]"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:902
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:37:52 GMT
last-modified:Fri, 30 Jan 2026 18:37:52 GMT
pragma:no-cache
server:nginx
x-request-id:253-23578048

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "13298-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "HLA-A [Type]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "13298-5","display" : "HLA-A [Type]"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#13298-5 (\"HLA-A [Type]\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#13298-5\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#975

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"258564008","display":"Buccal smear sample"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1069
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:37:53 GMT
last-modified:Fri, 30 Jan 2026 18:37:53 GMT
pragma:no-cache
server:nginx
x-request-id:253-23578070

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "258564008"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Buccal smear sample"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "258564008","display" : "Buccal smear sample"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://snomed.info/sct#258564008 (\"Buccal smear sample\")]\"\r\n0 0     : 0ms  : Check \"http://snomed.info/sct#258564008\"\r\n0 0     : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#976

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"122610009","display":"Specimen from lung obtained by biopsy (specimen)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1145
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:37:53 GMT
last-modified:Fri, 30 Jan 2026 18:37:53 GMT
pragma:no-cache
server:nginx
x-request-id:253-23578072

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "122610009"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Specimen from lung obtained by biopsy"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "122610009","display" : "Specimen from lung obtained by biopsy (specimen)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://snomed.info/sct#122610009 (\"Specimen from lung obtained by biopsy (specimen)\")]\"\r\n0 0     : 0ms  : Check \"http://snomed.info/sct#122610009\"\r\n0 0     : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#977

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"129314006","display":"Biopsy - action"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1057
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:37:53 GMT
last-modified:Fri, 30 Jan 2026 18:37:53 GMT
pragma:no-cache
server:nginx
x-request-id:253-23578073

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "129314006"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Biopsy - action"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "129314006","display" : "Biopsy - action"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://snomed.info/sct#129314006 (\"Biopsy - action\")]\"\r\n0 0     : 0ms  : Check \"http://snomed.info/sct#129314006\"\r\n0 0     : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#978

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"119297000","display":"Blood specimen (specimen)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1076
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:37:53 GMT
last-modified:Fri, 30 Jan 2026 18:37:53 GMT
pragma:no-cache
server:nginx
x-request-id:253-23578074

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "119297000"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Blood specimen"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "119297000","display" : "Blood specimen (specimen)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://snomed.info/sct#119297000 (\"Blood specimen (specimen)\")]\"\r\n0 0     : 0ms  : Check \"http://snomed.info/sct#119297000\"\r\n0 0     : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#979

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"418622002","display":"Taking oral swab (procedure)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1096
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:37:53 GMT
last-modified:Fri, 30 Jan 2026 18:37:53 GMT
pragma:no-cache
server:nginx
x-request-id:253-23578076

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "418622002"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Taking oral swab (procedure)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "418622002","display" : "Taking oral swab (procedure)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://snomed.info/sct#418622002 (\"Taking oral swab (procedure)\")]\"\r\n0 0     : 0ms  : Check \"http://snomed.info/sct#418622002\"\r\n0 0     : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#980

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"261063000","display":"Buccal space"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1048
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:37:53 GMT
last-modified:Fri, 30 Jan 2026 18:37:53 GMT
pragma:no-cache
server:nginx
x-request-id:253-23578080

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "261063000"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Buccal space"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "261063000","display" : "Buccal space"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://snomed.info/sct#261063000 (\"Buccal space\")]\"\r\n0 0     : 0ms  : Check \"http://snomed.info/sct#261063000\"\r\n0 0     : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#981

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"3341006","display":"Right lung structure (body structure)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1088
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:37:53 GMT
last-modified:Fri, 30 Jan 2026 18:37:53 GMT
pragma:no-cache
server:nginx
x-request-id:253-23578082

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "3341006"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Right lung"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "3341006","display" : "Right lung structure (body structure)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://snomed.info/sct#3341006 (\"Right lung structure (body structure)\")]\"\r\n0 0     : 0ms  : Check \"http://snomed.info/sct#3341006\"\r\n0 0     : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#982

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26421-0"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL4049-4","name":"LOINCAnswersLL4049-4","title":"LOINC Answer Codes for LL4049-4","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL4049-4"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1173
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:37:55 GMT
last-modified:Fri, 30 Jan 2026 18:37:55 GMT
pragma:no-cache
server:nginx
x-request-id:253-23578083

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26421-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Consider alternative medication"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26421-0"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL4049-4 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL4049-4)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA26421-0 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA26421-0\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL4049-4) at CodeableConcept.coding[0]\r\n1360 1360: 1360ms : Filter \"LIST=LL4049-4\": Code \"LA26421-0\" found in http://loinc.org|2.81\r\n"}]}

#983

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26421-0","display":"Consider alternative medication"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL1037-2","name":"LOINCAnswersLL1037-2","title":"LOINC Answer Codes for LL1037-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL1037-2"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2271
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:37:57 GMT
last-modified:Fri, 30 Jan 2026 18:37:57 GMT
pragma:no-cache
server:nginx
x-request-id:253-23578101

{"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1037-2'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26421-0","display" : "Consider alternative medication"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA26421-0 ('Consider alternative medication')' was not found in the value set 'http://loinc.org/vs/LL1037-2'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1037-2'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL1037-2 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL1037-2)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA26421-0 (\"Consider alternative medication\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA26421-0\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL1037-2) at CodeableConcept.coding[0]\r\n2015 2015: 2015ms : Filter \"LIST=LL1037-2\": Code \"LA26421-0\" not found in http://loinc.org|2.81\r\n"}]}

#984

POST https://tx.fhir.org/r4/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26422-8","display":"Decrease dose"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL1037-2","name":"LOINCAnswersLL1037-2","title":"LOINC Answer Codes for LL1037-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL1037-2"}]}]}}},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2217
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:37:59 GMT
last-modified:Fri, 30 Jan 2026 18:37:59 GMT
pragma:no-cache
server:nginx
x-request-id:253-23578137

{"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1037-2'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26422-8","display" : "Decrease dose"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA26422-8 ('Decrease dose')' was not found in the value set 'http://loinc.org/vs/LL1037-2'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1037-2'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL1037-2 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL1037-2)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA26422-8 (\"Decrease dose\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA26422-8\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL1037-2) at CodeableConcept.coding[0]\r\n2015 2015: 2015ms : Filter \"LIST=LL1037-2\": Code \"LA26422-8\" not found in http://loinc.org|2.81\r\n"}]}

#985

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:23 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:5509a8a2-4359-4bd1-8bcd-aeb04c309843
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:5509a8a2-4359-4bd1-8bcd-aeb04c309843
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#986

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:23 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:31aa9b10-9134-40dc-a30a-08dce0fabf31
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:31aa9b10-9134-40dc-a30a-08dce0fabf31
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#987

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:24 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:fcccb016-7f21-4cf1-a0ea-a327a03427aa
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:fcccb016-7f21-4cf1-a0ea-a327a03427aa
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#988

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:24 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:22cb5b82-a2cd-4e6d-92d4-138e8bf233cd
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:22cb5b82-a2cd-4e6d-92d4-138e8bf233cd
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#989

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:25 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:47569c53-7bd1-40e0-8264-b81c32c91f2a
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:47569c53-7bd1-40e0-8264-b81c32c91f2a
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#990

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:25 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:864cd693-042a-4d5f-afb0-c4cb4766abff
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:864cd693-042a-4d5f-afb0-c4cb4766abff
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#991

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:26 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:9e882425-89c1-4436-a56c-3cb667701ac7
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:9e882425-89c1-4436-a56c-3cb667701ac7
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#992

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:26 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:a42e3613-2ba0-4dee-acc1-6929d05aa43f
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:a42e3613-2ba0-4dee-acc1-6929d05aa43f
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#993

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:27 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:62303d57-2f7a-4020-8e64-499a41cbd974
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:62303d57-2f7a-4020-8e64-499a41cbd974
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#994

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:27 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:6dfa644e-503f-441a-ab4a-9012e44cdce6
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:6dfa644e-503f-441a-ab4a-9012e44cdce6
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#995

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:28 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:e0a06620-aefc-46a3-8668-c0b8831e9bf9
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:e0a06620-aefc-46a3-8668-c0b8831e9bf9
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#996

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:29 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:f749314d-4b81-4652-a91e-a28073e546e5
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:f749314d-4b81-4652-a91e-a28073e546e5
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#997

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:29 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:9f73a84a-eee9-4865-8188-354524779071
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:9f73a84a-eee9-4865-8188-354524779071
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#998

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:30 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:8fd2502f-01ab-40ca-9b49-d3376f4de6cb
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:8fd2502f-01ab-40ca-9b49-d3376f4de6cb
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#999

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:30 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:eed1cf3c-796d-4abe-badf-6719c2e462ae
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:eed1cf3c-796d-4abe-badf-6719c2e462ae
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1000

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:31 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:c795cf09-94e0-468b-a4cb-e8dbf6b6009b
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:c795cf09-94e0-468b-a4cb-e8dbf6b6009b
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1001

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:31 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:dbe9992e-1d5b-4bc9-bab6-91e7dd9fce3b
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:dbe9992e-1d5b-4bc9-bab6-91e7dd9fce3b
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1002

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:32 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:0d6a8ed7-2daf-4900-8ab5-04c00fd48e0e
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:0d6a8ed7-2daf-4900-8ab5-04c00fd48e0e
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1003

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:32 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:7cf5491c-b16b-4ce6-8519-4fed0a55a6be
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:7cf5491c-b16b-4ce6-8519-4fed0a55a6be
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1004

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:33 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:45efc891-e7ae-4a82-a3a1-ed68580721a0
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:45efc891-e7ae-4a82-a3a1-ed68580721a0
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1005

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:33 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:5ea897c3-4038-4c85-b5a6-82103c3319b7
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:5ea897c3-4038-4c85-b5a6-82103c3319b7
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1006

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:34 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:3623d9b2-ac36-4ef7-b8cb-af42d4ab32cb
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:3623d9b2-ac36-4ef7-b8cb-af42d4ab32cb
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1007

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:34 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:cad1b79c-919f-4668-a76f-09c17d768f39
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:cad1b79c-919f-4668-a76f-09c17d768f39
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1008

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:35 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:655a3bb2-62a1-47ba-8d09-3e3b5ff728e1
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:655a3bb2-62a1-47ba-8d09-3e3b5ff728e1
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1009

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:35 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:6a2a8e11-ed88-4a8f-9a8c-edfee5244be5
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:6a2a8e11-ed88-4a8f-9a8c-edfee5244be5
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1010

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:36 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:3a3fd37b-ec7d-4312-9b87-9cb51ee4232c
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:3a3fd37b-ec7d-4312-9b87-9cb51ee4232c
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1011

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:36 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:e0a0dd94-d92d-48cb-9d64-022f45b407e4
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:e0a0dd94-d92d-48cb-9d64-022f45b407e4
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1012

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:37 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:8d069e39-4d0a-47cc-9484-80d55792a17f
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:8d069e39-4d0a-47cc-9484-80d55792a17f
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1013

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:37 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:9f9ada62-cc5c-46e0-b178-3a9111395a27
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:9f9ada62-cc5c-46e0-b178-3a9111395a27
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1014

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:38 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:fed74e84-faf7-4419-94d3-9d446c71a0b0
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:fed74e84-faf7-4419-94d3-9d446c71a0b0
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1015

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:39 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:2f931f02-5679-4d3a-a192-2164c4ed1598
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:2f931f02-5679-4d3a-a192-2164c4ed1598
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1016

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:39 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:79de492c-b4fb-4939-b509-2759bc76a372
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:79de492c-b4fb-4939-b509-2759bc76a372
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1017

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:40 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:f65f1406-543a-42ea-be66-98438a11901f
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:f65f1406-543a-42ea-be66-98438a11901f
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1018

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:40 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:c8a4f190-22af-4f96-b3bb-d3ebbacafc87
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:c8a4f190-22af-4f96-b3bb-d3ebbacafc87
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1019

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:41 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:0aff22a2-855c-4045-9ab1-191362fcfb9b
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:0aff22a2-855c-4045-9ab1-191362fcfb9b
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1020

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:41 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:db70c2e1-e836-4910-8362-1b98cfedca70
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:db70c2e1-e836-4910-8362-1b98cfedca70
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1021

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:42 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:68dedd34-5f53-4724-b937-638abd3e442f
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:68dedd34-5f53-4724-b937-638abd3e442f
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1022

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:42 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:6e6e420c-98ff-4922-9915-2295ec9b8f94
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:6e6e420c-98ff-4922-9915-2295ec9b8f94
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1023

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:43 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:091cf040-eff9-477e-8d80-f91f5887084f
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:091cf040-eff9-477e-8d80-f91f5887084f
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1024

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:43 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:550e6d8d-f194-4b87-b41c-08bf0d8dfbb3
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:550e6d8d-f194-4b87-b41c-08bf0d8dfbb3
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1025

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:44 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:1f797095-925e-45a2-9ac9-ccf85cd755f5
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:1f797095-925e-45a2-9ac9-ccf85cd755f5
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1026

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:44 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:c02ca97c-833f-4cad-8aea-09707319506a
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:c02ca97c-833f-4cad-8aea-09707319506a
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1027

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:45 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:1f223573-008d-4977-a344-1e594a96d45d
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:1f223573-008d-4977-a344-1e594a96d45d
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1028

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:45 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:bb485e05-4b19-4844-9f24-171071cd588f
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:bb485e05-4b19-4844-9f24-171071cd588f
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1029

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:46 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:e86507a9-d19c-4ece-8544-5cf4cb05bc7f
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:e86507a9-d19c-4ece-8544-5cf4cb05bc7f
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1030

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:47 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:40a5e9c6-bda1-4195-869c-9b6ec5c93940
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:40a5e9c6-bda1-4195-869c-9b6ec5c93940
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1031

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:47 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:cb54307e-062b-4b8f-8853-b88751cf59a6
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:cb54307e-062b-4b8f-8853-b88751cf59a6
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1032

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:48 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:f9496e9c-e485-43f5-8009-e378007907b9
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:f9496e9c-e485-43f5-8009-e378007907b9
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1033

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:48 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:dba2fe2a-8e50-49e5-822b-0b90472bef41
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:dba2fe2a-8e50-49e5-822b-0b90472bef41
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1034

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:49 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:61a57d1c-86dd-495b-8481-68bcc2b0b820
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:61a57d1c-86dd-495b-8481-68bcc2b0b820
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1035

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:49 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:a383941a-d175-45a4-bc78-b32555d9e529
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:a383941a-d175-45a4-bc78-b32555d9e529
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1036

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:50 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:7ed117df-a1cc-468f-a447-3ce2ca56d09c
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:7ed117df-a1cc-468f-a447-3ce2ca56d09c
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1037

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:50 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:ebaced6b-0365-4c30-bd68-c00bc3177685
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:ebaced6b-0365-4c30-bd68-c00bc3177685
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1038

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:51 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:ead46cf8-7af1-49c1-aa1f-e465281241f6
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:ead46cf8-7af1-49c1-aa1f-e465281241f6
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1039

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:51 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:240afc74-b1f8-4c08-89fc-21e0de0b8d04
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:240afc74-b1f8-4c08-89fc-21e0de0b8d04
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1040

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:52 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:295ad5be-5a7a-4027-b227-9285dd55324d
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:295ad5be-5a7a-4027-b227-9285dd55324d
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1041

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:52 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:8e7ff5de-d7b7-469e-a7a5-7cf8c0875f2e
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:8e7ff5de-d7b7-469e-a7a5-7cf8c0875f2e
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1042

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:53 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:05a494cf-8799-4ce1-b482-92a7c846c215
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:05a494cf-8799-4ce1-b482-92a7c846c215
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1043

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:53 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:a6f77401-17d6-4756-afbd-309fe113e0fa
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:a6f77401-17d6-4756-afbd-309fe113e0fa
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1044

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:54 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:396cd25b-7c86-4bd8-9417-86180439c8ea
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:396cd25b-7c86-4bd8-9417-86180439c8ea
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1045

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:55 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:619b06ac-6014-4070-abe3-cf8d47f24872
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:619b06ac-6014-4070-abe3-cf8d47f24872
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1046

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:55 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:0f836954-c833-455b-b6f7-58894eac4825
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:0f836954-c833-455b-b6f7-58894eac4825
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1047

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:56 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:81545297-52bf-432d-bfc3-ed60c585fba3
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:81545297-52bf-432d-bfc3-ed60c585fba3
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1048

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:56 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:39b3596f-42cd-4631-a5ae-7796a1b4591d
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:39b3596f-42cd-4631-a5ae-7796a1b4591d
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1049

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:57 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:13e6c282-9d22-41b3-ad48-21d37796ec76
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:13e6c282-9d22-41b3-ad48-21d37796ec76
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1050

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:57 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:4d315f4c-2c64-44b7-9950-a8eb89f49be2
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:4d315f4c-2c64-44b7-9950-a8eb89f49be2
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1051

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:58 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:8097dcda-8e99-47f0-b7d7-b03d7a6941e2
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:8097dcda-8e99-47f0-b7d7-b03d7a6941e2
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1052

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:58 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:a7c43a2b-4996-4497-82f7-7842a5793297
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:a7c43a2b-4996-4497-82f7-7842a5793297
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1053

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:59 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:89a14dbf-576b-470d-890a-ca39831a8ecf
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:89a14dbf-576b-470d-890a-ca39831a8ecf
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1054

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:38:59 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:5ca34b79-2ea1-432c-903a-ab4294cc4bd7
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:5ca34b79-2ea1-432c-903a-ab4294cc4bd7
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1055

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:39:00 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:f604ab5d-2711-402f-8566-0af5f8736b83
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:f604ab5d-2711-402f-8566-0af5f8736b83
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1056

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:39:00 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:c3d692f4-c410-4040-892d-d0bfd6bb0f99
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:c3d692f4-c410-4040-892d-d0bfd6bb0f99
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1057

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:39:01 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:add92a19-7653-461b-9b8c-4b5b80bba5e3
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:add92a19-7653-461b-9b8c-4b5b80bba5e3
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1058

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:39:01 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:e26aa32f-0b03-4e5b-9398-8ae8ba056cc6
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:e26aa32f-0b03-4e5b-9398-8ae8ba056cc6
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1059

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_014049.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:39:02 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:7da13abd-f962-406e-92e3-6219041dbf88
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:7da13abd-f962-406e-92e3-6219041dbf88
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NM_014049.4"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1060

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NG_017064.1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:39:03 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:5ce04c92-9916-4c5e-9864-158a9c1a5bd1
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:5ce04c92-9916-4c5e-9864-158a9c1a5bd1
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NG_017064.1"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1061

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/projects/SNP","code":"rs368949613"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:39:03 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:e9a5f229-f9d7-4717-bef4-f751b724baf5
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:e9a5f229-f9d7-4717-bef4-f751b724baf5
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"rs368949613"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/projects/SNP was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/projects/SNP was not found"}]}

#1062

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_000106.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:39:04 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:a2e279b4-d0b1-48c1-9acf-0f820e6c091f
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:a2e279b4-d0b1-48c1-9acf-0f820e6c091f
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NM_000106.5"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1063

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_000106.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:39:04 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:f4211515-e1de-4db8-b999-dd35e59d7151
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:f4211515-e1de-4db8-b999-dd35e59d7151
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NM_000106.5"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1064

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_014049.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:39:05 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:f5e3586d-8b5f-40bd-a670-bc66e2cf2e06
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:f5e3586d-8b5f-40bd-a670-bc66e2cf2e06
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NM_014049.4"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1065

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NG_017064.1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:39:05 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:4ae7d736-9645-4fd7-95a6-c59860efcc4f
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:4ae7d736-9645-4fd7-95a6-c59860efcc4f
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NG_017064.1"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1066

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_000106.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:39:06 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:b0c74f5f-8f26-41e5-8db5-264dbecd69a9
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:b0c74f5f-8f26-41e5-8db5-264dbecd69a9
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NM_000106.5"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1067

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_000106.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:39:07 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:9daf71b1-62ca-4d3f-930d-9f19567b443a
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:9daf71b1-62ca-4d3f-930d-9f19567b443a
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NM_000106.5"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1068

GET https://tx.fhir.org/r4/CodeSystem?_format=json&url=http%3A%2F%2Fhl7.org%2Ffhir%2FCodeSystem%2Fmedicationknowledge-status HTTP/1.0
User-Agent: hapi-fhir-tooling-client
Accept: application/fhir+json; fhirVersion=4.0

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:275
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:39:07 GMT
pragma:no-cache
server:nginx
x-request-id:253-23579268

{"resourceType" : "Bundle","id" : "4cb71b55-5625-4fa5-9b5b-77f131eafc","meta" : {"lastUpdated" : "2026-01-30T18:39:07.785Z"},"type" : "searchset","total" : 0,"link" : [{"relation" : "self","url" : "CodeSystem?&url=http://hl7.org/fhir/CodeSystem/medicationknowledge-status"}]}

#1069

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://hl7.org/fhir/CodeSystem/medicationknowledge-status","code":"active"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1676
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:39:07 GMT
last-modified:Fri, 30 Jan 2026 18:39:07 GMT
pragma:no-cache
server:nginx
x-request-id:253-23579269

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://hl7.org/fhir/CodeSystem/medicationknowledge-status"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://hl7.org/fhir/CodeSystem/medicationknowledge-status"},{"name" : "code","valueCode" : "active"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://hl7.org/fhir/CodeSystem/medicationknowledge-status' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://hl7.org/fhir/CodeSystem/medicationknowledge-status' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://hl7.org/fhir/CodeSystem/medicationknowledge-status#active (\"\")]\"\r\n0 0     : 0ms  : Check \"http://hl7.org/fhir/CodeSystem/medicationknowledge-status#active\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://hl7.org/fhir/CodeSystem/medicationknowledge-status\"\r\n"}]}

#1070

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:39:08 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:c114d894-8e0d-489f-8430-6142efef8b3b
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:c114d894-8e0d-489f-8430-6142efef8b3b
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1071

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:39:09 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:7d1171e1-4bbe-4bc2-9fa9-84b242a2b70c
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:7d1171e1-4bbe-4bc2-9fa9-84b242a2b70c
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"NC_000010.10"},{"name":"system","valueUri":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.ncbi.nlm.nih.gov/refseq"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.ncbi.nlm.nih.gov/refseq was not found"}]}

#1072

POST https://tx.fhir.org/r4/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://loinc.org"}]}}}]}

422
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
connection:keep-alive
content-length:474
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:39:15 GMT
server:nginx
x-request-id:253-23579357

{"resourceType" : "OperationOutcome","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>The value set '' expansion has too many codes to display (&gt;10000)</p></div>"},"issue" : [{"severity" : "error","code" : "too-costly","details" : {"text" : "The value set '' expansion has too many codes to display (>10000)"},"diagnostics" : "0 0 : start\r\n16 16   : not in cache\r\n16 0    : 0ms start working\r\n16 0    : 0ms compose #1\r\n"}]}

#1073

POST https://tx.fhir.org/r4/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"_limit","valueInteger":10000},{"name":"_incomplete","valueBoolean":true},{"name":"displayLanguage","valueCode":"en"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"observation-codes","meta":{"lastUpdated":"2019-11-01T09:29:23.356+11:00","profile":["http://hl7.org/fhir/StructureDefinition/shareablevalueset"]},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"fhir"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"draft"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":1}],"url":"http://hl7.org/fhir/ValueSet/observation-codes","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.396"}],"version":"4.0.1","name":"LOINCCodes","title":"LOINC Codes","status":"draft","experimental":false,"date":"2019-11-01T09:29:23+11:00","publisher":"FHIR Project team","contact":[{"telecom":[{"system":"url","value":"http://hl7.org/fhir"}]}],"description":"This value set includes all LOINC codes","copyright":"This content from LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use.","compose":{"include":[{"system":"http://loinc.org"}]}}}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:123593
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:39:18 GMT
last-modified:Fri, 30 Jan 2026 18:39:17 GMT
pragma:no-cache
server:nginx
x-request-id:253-23579358

{"resourceType" : "ValueSet","meta" : {"lastUpdated" : "2019-11-01T09:29:23.356+11:00","profile" : ["http://hl7.org/fhir/StructureDefinition/shareablevalueset"]},"url" : "http://hl7.org/fhir/ValueSet/observation-codes","identifier" : [{"system" : "urn:ietf:rfc:3986","value" : "urn:oid:2.16.840.1.113883.4.642.3.396"}],"version" : "4.0.1","name" : "LOINCCodes","title" : "LOINC Codes","status" : "draft","experimental" : false,"date" : "2019-11-01T09:29:23+11:00","expansion" : {"extension" : [{"extension" : [{"url" : "uri","valueUri" : "http://hl7.org/fhir/concept-properties#status"},{"url" : "code","valueCode" : "status"}],"url" : "http://hl7.org/fhir/5.0/StructureDefinition/extension-ValueSet.expansion.property"}],"identifier" : "urn:uuid:89918ff8-4297-4536-9eca-b611c69c1ae1","timestamp" : "2026-01-30T18:39:15.550Z","offset" : 0,"parameter" : [{"name" : "limitedExpansion","valueBoolean" : true},{"name" : "displayLanguage","valueCode" : "en"},{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://loinc.org|2.81"}],"contains" : [{"system" : "http://loinc.org","code" : "100000-9","display" : "Health informatics pioneer and the father of LOINC"},{"system" : "http://loinc.org","code" : "100001-7","display" : "Health informatics pioneer and cofounder of LOINC"},{"system" : "http://loinc.org","code" : "100002-5","display" : "Specimen care is maintained"},{"system" : "http://loinc.org","code" : "100003-3","display" : "Team communication is maintained throughout care"},{"system" : "http://loinc.org","code" : "100004-1","display" : "Demonstrates knowledge of the expected psychosocial responses to the procedure"},{"system" : "http://loinc.org","code" : "100005-8","display" : "Demonstrates knowledge of nutritional management related to the procedure"},{"system" : "http://loinc.org","code" : "100006-6","display" : "Demonstrates knowledge of medication 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"http://loinc.org","code" : "100027-2","display" : "SMAD4 gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal"},{"system" : "http://loinc.org","code" : "100028-0","display" : "FBXW7 gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal"},{"system" : "http://loinc.org","code" : "100029-8","display" : "Cancer related multigene analysis in Plasma cell-free DNA by Molecular genetics method"},{"system" : "http://loinc.org","code" : "100030-6","display" : "Axis I: Temporal aspects score [Mainz Pain Staging System]"},{"system" : "http://loinc.org","code" : "100031-4","display" : "Axis II: Spatial aspects score [Mainz Pain Staging System]"},{"system" : "http://loinc.org","code" : "10003-2","display" : "R wave duration in lead III"},{"system" : "http://loinc.org","code" : "100032-2","display" : "Axis III: Drug taking behavior score [Mainz Pain Staging System]"},{"system" : "http://loinc.org","code" : "100033-0","display" 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sucrose [Presence] in Isolate"},{"system" : "http://loinc.org","code" : "100873-9","display" : "Giardia lamblia tpi gene [Genotype] in Specimen by Molecular genetics method"},{"system" : "http://loinc.org","code" : "100874-7","display" : "Basidiobolus sp [Presence] in Specimen"},{"system" : "http://loinc.org","code" : "10087-5","display" : "ST initial amplitude 6 ms in lead III"},{"system" : "http://loinc.org","code" : "100875-4","display" : "Fetal Heart Document limited US"},{"system" : "http://loinc.org","code" : "100876-2","display" : "Fetal Heart Document US"},{"system" : "http://loinc.org","code" : "100877-0","display" : "US Heart Transesophageal during surgery"},{"system" : "http://loinc.org","code" : "100878-8","display" : "Endoscopic ultrasound study Upper GI tract Document"},{"system" : "http://loinc.org","code" : "100879-6","display" : "US Guidance for cryoablation of Breast - right"},{"system" : "http://loinc.org","code" : "100880-4","display" : "US Guidance for cryoablation of Breast - left"},{"system" : "http://loinc.org","code" : "100881-2","display" : "MR Guidance for cryoablation of Bone"},{"system" : "http://loinc.org","code" : "100882-0","display" : "MR Peritoneum W contrast percutaneous intraperitoneal"},{"system" : "http://loinc.org","code" : "10088-3","display" : "ST initial amplitude 6 ms in lead V1"},{"system" : "http://loinc.org","code" : "100883-8","display" : "MR Guidance for biopsy of Kidney - left"},{"system" : "http://loinc.org","code" : "100884-6","display" : "MR Guidance for biopsy of Kidney - right"},{"system" : "http://loinc.org","code" : "100885-3","display" : "Parapoxvirus DNA [Presence] in Specimen by NAA with probe detection"},{"system" : "http://loinc.org","code" : "100886-1","display" : "Orf virus DNA [Presence] in Specimen by NAA with probe detection"},{"system" : "http://loinc.org","code" : "100887-9","display" : "Pseudocowpox virus DNA [Presence] in Specimen by NAA with probe detection"},{"system" : "http://loinc.org","code" : "100888-7","display" : "Monkeypox virus clade II DNA [Presence] in Specimen by NAA with probe detection"},{"system" : "http://loinc.org","code" : "100889-5","display" : "Monkeypox virus clade I DNA [Presence] in Specimen by NAA with probe detection"},{"system" : "http://loinc.org","code" : "100890-3","display" : "Poxvirus DNA panel"},{"system" : "http://loinc.org","code" : "10089-1","display" : "ST initial amplitude 6 ms in lead V2"},{"system" : "http://loinc.org","code" : "100891-1","display" : "Orthopoxvirus IgG Ab [Presence] in Serum or Plasma by Immunoassay"},{"system" : "http://loinc.org","code" : "100892-9","display" : "Orthopoxvirus IgM Ab [Presence] in Serum or Plasma by Immunoassay"},{"system" : "http://loinc.org","code" : "100893-7","display" : "Orthopoxvirus IgG and IgM Ab panel - Serum or Plasma"},{"system" : "http://loinc.org","code" : "100894-5","display" : "Recommended screening frequency Narrative"},{"system" : "http://loinc.org","code" : "100895-2","display" : "Rickettsia conorii IgG and IgM [Interpretation] in Serum"},{"system" : "http://loinc.org","code" : "100896-0","display" : "Vasopressin [Moles/volume] in Plasma --13th specimen post XXX challenge"},{"system" : "http://loinc.org","code" : "100897-8","display" : "Staphylococcus aureus [Presence] in Specimen by Organism specific culture"},{"system" : "http://loinc.org","code" : "100898-6","display" : "Lipid panel - Serum or Plasma"},{"system" : "http://loinc.org","code" : "100899-4","display" : "Enterobacteriaceae.extended spectrum beta lactamase resistance phenotype [Identifier] in Specimen by Organism specific culture"}]}}

#1074

POST https://tx.fhir.org/r4/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL4034-6"}]}]}}}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:827
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:39:19 GMT
last-modified:Fri, 30 Jan 2026 18:39:19 GMT
pragma:no-cache
server:nginx
x-request-id:253-23579389

{"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:40e40d26-b0b3-4175-959c-b6e44bfed1f4","timestamp" : "2026-01-30T18:39:18.191Z","total" : 5,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://loinc.org|2.81"}],"contains" : [{"system" : "http://loinc.org","code" : "LA6668-3","display" : "Pathogenic"},{"system" : "http://loinc.org","code" : "LA26332-9","display" : "Likely pathogenic"},{"system" : "http://loinc.org","code" : "LA26333-7","display" : "Uncertain significance"},{"system" : "http://loinc.org","code" : "LA26334-5","display" : "Likely benign"},{"system" : "http://loinc.org","code" : "LA6675-8","display" : "Benign"}]}}

#1075

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://human-phenotype-ontology.org","concept":[{"code":"HP:0000006","display":"Autosomal dominant inheritance"},{"code":"HP:0000007","display":"Autosomal recessive inheritance"},{"code":"HP:0001417","display":"X-linked inheritance"},{"code":"HP:0001419","display":"X-linked recessive inheritance"},{"code":"HP:0001423","display":"X-linked dominant inheritance"},{"code":"HP:0001426","display":"Multifactorial inheritance"},{"code":"HP:0001427","display":"Mitochondrial inheritance"},{"code":"HP:0001442","display":"Typified by somatic mosaicism"},{"code":"HP:0001450","display":"Y-linked inheritance"},{"code":"HP:0001470","display":"Sex-limited expression"},{"code":"HP:0003743","display":"Genetic anticipation"},{"code":"HP:0003745","display":"Sporadic"},{"code":"HP:0010983","display":"Oligogenic inheritance"},{"code":"HP:0012274","display":"Autosomal dominant inheritance with paternal imprinting"},{"code":"HP:0012275","display":"Autosomal dominant inheritance with maternal imprinting"},{"code":"HP:0025352","display":"Typically de novo"},{"code":"HP:0032113","display":"Semidominant inheritance"}]}]}}}]}

200
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content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:39:19 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:6be82eb6-9b37-477c-85dd-0984982bb30b
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:6be82eb6-9b37-477c-85dd-0984982bb30b
x-xss-protection:0

{"resourceType":"ValueSet","status":"active","expansion":{"identifier":"urn:uuid:31418216-f2ca-4e5b-998c-16d428e248d9","timestamp":"2026-01-30T19:39:19+01:00","total":0,"offset":0,"parameter":[{"name":"used-codesystem","valueUri":"http://human-phenotype-ontology.org|1.0.0"},{"name":"version","valueUri":"http://human-phenotype-ontology.org|1.0.0"},{"name":"excludeNested","valueBoolean":false},{"name":"offset","valueInteger":0},{"name":"count","valueInteger":1000}]}}

#1076

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://www.genenames.org"}]}}}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:39:21 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:898ce2ec-3cda-41c6-805e-a9ebdf68844f
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:898ce2ec-3cda-41c6-805e-a9ebdf68844f
x-xss-protection:0

{"resourceType":"ValueSet","status":"active","expansion":{"identifier":"urn:uuid:259bcfe1-1662-4d4f-ac76-de13b87ecc93","timestamp":"2026-01-30T19:39:21+01:00","total":0,"offset":0,"parameter":[{"name":"used-codesystem","valueUri":"http://www.genenames.org|3.1.0"},{"name":"version","valueUri":"http://www.genenames.org|3.1.0"},{"name":"excludeNested","valueBoolean":false},{"name":"offset","valueInteger":0},{"name":"count","valueInteger":1000}]}}

#1077

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://www.genenames.org/genegroup"}]}}}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:39:22 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:63f1dd2c-c82b-4fde-bf3e-59a57f244ce7
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:63f1dd2c-c82b-4fde-bf3e-59a57f244ce7
x-xss-protection:0

{"resourceType":"ValueSet","status":"active","expansion":{"identifier":"urn:uuid:1af07c0e-c515-4097-a897-cbb10f3d89cf","timestamp":"2026-01-30T19:39:22+01:00","total":0,"offset":0,"parameter":[{"name":"used-codesystem","valueUri":"http://www.genenames.org/genegroup|1.1.0"},{"name":"version","valueUri":"http://www.genenames.org/genegroup|1.1.0"},{"name":"excludeNested","valueBoolean":true},{"name":"offset","valueInteger":0},{"name":"count","valueInteger":1000}]}}

#1078

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"62374-4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:772
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:39:23 GMT
last-modified:Fri, 30 Jan 2026 18:39:23 GMT
pragma:no-cache
server:nginx
x-request-id:253-23579439

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "62374-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Human reference sequence assembly version"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#62374-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#62374-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1079

POST https://tx.fhir.org/r4/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL1040-6"}]}]}}}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:814
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:39:24 GMT
last-modified:Fri, 30 Jan 2026 18:39:24 GMT
pragma:no-cache
server:nginx
x-request-id:253-23579460

{"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:771314dc-b010-4b73-bed2-2cffb3813d10","timestamp" : "2026-01-30T18:39:23.957Z","total" : 5,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://loinc.org|2.81"}],"contains" : [{"system" : "http://loinc.org","code" : "LA14032-9","display" : "NCBI Build 34"},{"system" : "http://loinc.org","code" : "LA14029-5","display" : "GRCh37"},{"system" : "http://loinc.org","code" : "LA14030-3","display" : "NCBI Build 36.1"},{"system" : "http://loinc.org","code" : "LA14031-1","display" : "NCBI Build 35"},{"system" : "http://loinc.org","code" : "LA26806-2","display" : "GRCh38"}]}}

#1080

POST https://tx.fhir.org/r4/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL2938-0"}]}]}}}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2355
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:39:26 GMT
last-modified:Fri, 30 Jan 2026 18:39:26 GMT
pragma:no-cache
server:nginx
x-request-id:253-23579475

{"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:4456c562-5e73-41b8-b442-83468bb8b2b7","timestamp" : "2026-01-30T18:39:25.082Z","total" : 24,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://loinc.org|2.81"}],"contains" : [{"system" : "http://loinc.org","code" : "LA21254-0","display" : "Chromosome 1"},{"system" : "http://loinc.org","code" : "LA21255-7","display" : "Chromosome 2"},{"system" : "http://loinc.org","code" : "LA21256-5","display" : "Chromosome 3"},{"system" : "http://loinc.org","code" : "LA21257-3","display" : "Chromosome 4"},{"system" : "http://loinc.org","code" : "LA21258-1","display" : "Chromosome 5"},{"system" : "http://loinc.org","code" : "LA21259-9","display" : "Chromosome 6"},{"system" : "http://loinc.org","code" : "LA21260-7","display" : "Chromosome 7"},{"system" : "http://loinc.org","code" : "LA21261-5","display" : "Chromosome 8"},{"system" : "http://loinc.org","code" : "LA21262-3","display" : "Chromosome 9"},{"system" : "http://loinc.org","code" : "LA21263-1","display" : "Chromosome 10"},{"system" : "http://loinc.org","code" : "LA21264-9","display" : "Chromosome 11"},{"system" : "http://loinc.org","code" : "LA21265-6","display" : "Chromosome 12"},{"system" : "http://loinc.org","code" : "LA21266-4","display" : "Chromosome 13"},{"system" : "http://loinc.org","code" : "LA21267-2","display" : "Chromosome 14"},{"system" : "http://loinc.org","code" : "LA21268-0","display" : "Chromosome 15"},{"system" : "http://loinc.org","code" : "LA21269-8","display" : "Chromosome 16"},{"system" : "http://loinc.org","code" : "LA21270-6","display" : "Chromosome 17"},{"system" : "http://loinc.org","code" : "LA21271-4","display" : "Chromosome 18"},{"system" : "http://loinc.org","code" : "LA21272-2","display" : "Chromosome 19"},{"system" : "http://loinc.org","code" : "LA21273-0","display" : "Chromosome 20"},{"system" : "http://loinc.org","code" : "LA21274-8","display" : "Chromosome 21"},{"system" : "http://loinc.org","code" : "LA21275-5","display" : "Chromosome 22"},{"system" : "http://loinc.org","code" : "LA21276-3","display" : "Chromosome X"},{"system" : "http://loinc.org","code" : "LA21277-1","display" : "Chromosome Y"}]}}

#1081

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"92821-8"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:762
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:39:29 GMT
last-modified:Fri, 30 Jan 2026 18:39:29 GMT
pragma:no-cache
server:nginx
x-request-id:253-23579514

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "92821-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic frequency in Population"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#92821-8 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#92821-8\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1082

POST https://tx.fhir.org/r4/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL4050-2"}]}]}}}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:763
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:39:38 GMT
last-modified:Fri, 30 Jan 2026 18:39:38 GMT
pragma:no-cache
server:nginx
x-request-id:253-23579661

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#1083

POST https://tx.fhir.org/r4/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://loinc.org","concept":[{"code":"85337-4","display":"Estrogen receptor Ag [Presence] in Breast cancer specimen by Immune stain"},{"code":"72382-5","display":"HER2 [Units/volume] in Tissue by Immunoassay"},{"code":"77637-7","display":"HLA-A and B and C (class I) IgG panel [Identifier] - Serum or Plasma by Immunoassay"},{"code":"40557-1","display":"Progesterone receptor Ag [Presence] in Tissue by Immune stain"},{"code":"85147-7","display":"PD-L1 by clone 22C3 in Tissue by Immune stain Report"},{"code":"59025-7","display":"Neutrophil Ab [Units/volume] in Serum by Flow cytometry (FC)"},{"code":"59003-4","display":"Lactoferrin Ab [Units/volume] in Serum by Immunoassay"},{"code":"10495-0","display":"Insulin Ag [Presence] in Tissue by Immune stain"},{"code":"16550-6","display":"Carbohydrates [Identifier] in Urine"},{"code":"2569-2","display":"Lipids [Mass/volume] in Serum"},{"code":"4551-8","display":"Hemoglobin A2/Hemoglobin.total in Blood"},{"code":"19195-7","display":"Prostate specific Ag [Units/volume] in Serum or Plasma"},{"code":"64083-9","display":"MGMT gene methylation score in Tissue by Molecular genetics method"},{"code":"62862-8","display":"Microsatellite instability [Presence] in Tissue by Immune stain"},{"code":"81704-9","display":"Microsatellite instability marker D17S250 in Cancer specimen Qualitative"},{"code":"94077-5","display":"Tumor mutation burden [Interpretation]"}]}]}}}]}

200
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access-control-allow-origin:*
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cache-control:public, max-age=600
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content-length:2345
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:39:40 GMT
last-modified:Fri, 30 Jan 2026 18:39:40 GMT
pragma:no-cache
server:nginx
x-request-id:253-23579710

{"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:31da8178-0678-4e74-a3f4-f4cf3d7cad6a","timestamp" : "2026-01-30T18:39:40.847Z","total" : 16,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://loinc.org|2.81"}],"contains" : [{"system" : "http://loinc.org","code" : "85337-4","display" : "Estrogen receptor Ag [Presence] in Breast cancer specimen by Immune stain"},{"system" : "http://loinc.org","code" : "72382-5","display" : "HER2 [Units/volume] in Tissue by Immunoassay"},{"system" : "http://loinc.org","code" : "77637-7","display" : "HLA-A and B and C (class I) IgG panel [Identifier] - Serum or Plasma by Immunoassay"},{"system" : "http://loinc.org","code" : "40557-1","display" : "Progesterone receptor Ag [Presence] in Tissue by Immune stain"},{"system" : "http://loinc.org","code" : "85147-7","display" : "PD-L1 by clone 22C3 in Tissue by Immune stain Report"},{"system" : "http://loinc.org","code" : "59025-7","display" : "Neutrophil Ab [Units/volume] in Serum by Flow cytometry (FC)"},{"system" : "http://loinc.org","code" : "59003-4","display" : "Lactoferrin Ab [Units/volume] in Serum by Immunoassay"},{"system" : "http://loinc.org","code" : "10495-0","display" : "Insulin Ag [Presence] in Tissue by Immune stain"},{"system" : "http://loinc.org","code" : "16550-6","display" : "Carbohydrates [Identifier] in Urine"},{"system" : "http://loinc.org","code" : "2569-2","display" : "Lipids [Mass/volume] in Serum"},{"system" : "http://loinc.org","code" : "4551-8","display" : "Hemoglobin A2/Hemoglobin.total in Blood"},{"system" : "http://loinc.org","code" : "19195-7","display" : "Prostate specific Ag [Units/volume] in Serum or Plasma"},{"system" : "http://loinc.org","code" : "64083-9","display" : "MGMT gene methylation score in Tissue by Molecular genetics method"},{"system" : "http://loinc.org","code" : "62862-8","display" : "Microsatellite instability [Presence] in Tissue by Immune stain"},{"system" : "http://loinc.org","code" : "81704-9","display" : "Microsatellite instability marker D17S250 in Cancer specimen Qualitative"},{"system" : "http://loinc.org","code" : "94077-5","display" : "Tumor mutation burden [Interpretation]"}]}}

#1084

POST https://tx.fhir.org/r4/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://varnomen.hgvs.org"}]}}}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:413
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:39:41 GMT
last-modified:Fri, 30 Jan 2026 18:39:41 GMT
pragma:no-cache
server:nginx
x-request-id:253-23579724

{"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:23c96ecc-f582-42cd-ade0-ddb64ce956c7","timestamp" : "2026-01-30T18:39:41.675Z","total" : 0,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://varnomen.hgvs.org|2.0"}]}}

#1085

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0001537"}]}]}}}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:39:42 GMT
server:nginx
vary:Origin
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vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:45a6b5c3-f042-4326-b508-b87d69f70071
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:45a6b5c3-f042-4326-b508-b87d69f70071
x-xss-protection:0

{"resourceType":"ValueSet","status":"active","expansion":{"identifier":"urn:uuid:2392575e-3c62-49b4-a399-e8709ccaca87","timestamp":"2026-01-30T19:39:42+01:00","total":0,"offset":0,"parameter":[{"name":"used-codesystem","valueUri":"http://www.sequenceontology.org|1.0.0"},{"name":"version","valueUri":"http://www.sequenceontology.org|1.0.0"},{"name":"excludeNested","valueBoolean":false},{"name":"offset","valueInteger":0},{"name":"count","valueInteger":1000}]}}

#1086

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0001536"}]}]}}}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:39:42 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
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x-request-id:0ac2cbf4-6e83-45bb-8530-449e7a908c04
x-xss-protection:0

{"resourceType":"ValueSet","status":"active","expansion":{"identifier":"urn:uuid:5ddc416a-d470-40cb-9cdc-b3c2149b65fb","timestamp":"2026-01-30T19:39:42+01:00","total":0,"offset":0,"parameter":[{"name":"used-codesystem","valueUri":"http://www.sequenceontology.org|1.0.0"},{"name":"version","valueUri":"http://www.sequenceontology.org|1.0.0"},{"name":"excludeNested","valueBoolean":false},{"name":"offset","valueInteger":0},{"name":"count","valueInteger":1000}]}}

#1087

POST https://tx.fhir.org/r4/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://loinc.org","concept":[{"code":"LA10315-2","display":"Ultrarapid metabolizer"},{"code":"LA25391-6","display":"Normal metabolizer"},{"code":"LA25390-8","display":"Rapid metabolizer"},{"code":"LA10317-8","display":"Intermediate metabolizer"},{"code":"LA9657-3","display":"Poor metabolizer"},{"code":"LA19542-2","display":"Low Risk"},{"code":"LA19541-4","display":"High Risk"},{"code":"LA6676-6","display":"Resistant"},{"code":"LA6677-4","display":"Responsive"},{"code":"LA9660-7","display":"Presumed resistant"},{"code":"LA9661-5","display":"Presumed responsive"},{"code":"LA6682-4","display":"Unknown Significance"},{"code":"LA6675-8","display":"Benign"},{"code":"LA6674-1","display":"Presumed Benign"},{"code":"LA9662-3","display":"Presumed non-responsive"},{"code":"LA25392-4","display":"Increased function"},{"code":"LA25393-2","display":"Normal function"},{"code":"LA25395-7","display":"Decreased function"},{"code":"LA25394-0","display":"Poor function"}]}]}}}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2003
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:39:45 GMT
last-modified:Fri, 30 Jan 2026 18:39:45 GMT
pragma:no-cache
server:nginx
x-request-id:253-23579778

{"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:58bcadfa-5a1c-4ea3-bf2a-79759f676bcd","timestamp" : "2026-01-30T18:39:45.238Z","total" : 19,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://loinc.org|2.81"}],"contains" : [{"system" : "http://loinc.org","code" : "LA10315-2","display" : "Ultrarapid metabolizer"},{"system" : "http://loinc.org","code" : "LA25391-6","display" : "Normal metabolizer"},{"system" : "http://loinc.org","code" : "LA25390-8","display" : "Rapid metabolizer"},{"system" : "http://loinc.org","code" : "LA10317-8","display" : "Intermediate metabolizer"},{"system" : "http://loinc.org","code" : "LA9657-3","display" : "Poor metabolizer"},{"system" : "http://loinc.org","code" : "LA19542-2","display" : "Low risk"},{"system" : "http://loinc.org","code" : "LA19541-4","display" : "High risk"},{"system" : "http://loinc.org","code" : "LA6676-6","display" : "Resistant"},{"system" : "http://loinc.org","code" : "LA6677-4","display" : "Responsive"},{"system" : "http://loinc.org","code" : "LA9660-7","display" : "Presumed resistant"},{"system" : "http://loinc.org","code" : "LA9661-5","display" : "Presumed responsive"},{"system" : "http://loinc.org","code" : "LA6682-4","display" : "Unknown Significance"},{"system" : "http://loinc.org","code" : "LA6675-8","display" : "Benign"},{"system" : "http://loinc.org","code" : "LA6674-1","display" : "Presumed Benign"},{"system" : "http://loinc.org","code" : "LA9662-3","display" : "Presumed non-responsive"},{"system" : "http://loinc.org","code" : "LA25392-4","display" : "Increased function"},{"system" : "http://loinc.org","code" : "LA25393-2","display" : "Normal function"},{"system" : "http://loinc.org","code" : "LA25395-7","display" : "Decreased function"},{"system" : "http://loinc.org","code" : "LA25394-0","display" : "Poor function"}]}}

#1088

POST https://tx.fhir.org/r4/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://snomed.info/sct","concept":[{"code":"444734003","display":"Does not meet eligibility criteria for clinical trial (finding)"},{"code":"399223003","display":"Patient eligible for clinical trial (finding)"}]}]}}}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
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content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:39:45 GMT
last-modified:Fri, 30 Jan 2026 18:39:45 GMT
pragma:no-cache
server:nginx
x-request-id:253-23579784

{"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:7de44f14-6b61-46d4-9a87-edf1045bd64e","timestamp" : "2026-01-30T18:39:45.425Z","total" : 2,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : true},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201"}],"contains" : [{"system" : "http://snomed.info/sct","code" : "444734003","display" : "Does not meet eligibility criteria for clinical trial (finding)"},{"system" : "http://snomed.info/sct","code" : "399223003","display" : "Patient eligible for clinical trial (finding)"}]}}

#1089

POST https://tx.fhir.org/r4/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL1971-2"}]}]}}}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:724
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:39:48 GMT
last-modified:Fri, 30 Jan 2026 18:39:48 GMT
pragma:no-cache
server:nginx
x-request-id:253-23579806

{"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:5d6c3d27-77a7-4190-a722-be43f145d5e9","timestamp" : "2026-01-30T18:39:47.113Z","total" : 4,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://loinc.org|2.81"}],"contains" : [{"system" : "http://loinc.org","code" : "LA9633-4","display" : "Present"},{"system" : "http://loinc.org","code" : "LA9634-2","display" : "Absent"},{"system" : "http://loinc.org","code" : "LA18198-4","display" : "No call"},{"system" : "http://loinc.org","code" : "LA11884-6","display" : "Indeterminate"}]}}

#1090

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81291-7"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:743
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:39:48 GMT
last-modified:Fri, 30 Jan 2026 18:39:48 GMT
pragma:no-cache
server:nginx
x-request-id:253-23579825

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81291-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Variant ISCN"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81291-7 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81291-7\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1091

POST https://tx.fhir.org/r4/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL5323-2"}]}]}}}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:702
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:39:49 GMT
last-modified:Fri, 30 Jan 2026 18:39:49 GMT
pragma:no-cache
server:nginx
x-request-id:253-23579833

{"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:80cd558e-1b7a-443f-b3e8-3cb30d3af33a","timestamp" : "2026-01-30T18:39:48.988Z","total" : 3,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://loinc.org|2.81"}],"contains" : [{"system" : "http://loinc.org","code" : "LA30100-4","display" : "0-based interval counting"},{"system" : "http://loinc.org","code" : "LA30101-2","display" : "0-based character counting"},{"system" : "http://loinc.org","code" : "LA30102-0","display" : "1-based character counting"}]}}

#1092

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0002072"}]}]}}}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:39:50 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:ca59f3be-eac4-4952-87db-136c7a3461e5
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:ca59f3be-eac4-4952-87db-136c7a3461e5
x-xss-protection:0

{"resourceType":"ValueSet","status":"active","expansion":{"identifier":"urn:uuid:28f259cd-bf29-4512-ac35-57109ffb173f","timestamp":"2026-01-30T19:39:50+01:00","total":0,"offset":0,"parameter":[{"name":"used-codesystem","valueUri":"http://www.sequenceontology.org|1.0.0"},{"name":"version","valueUri":"http://www.sequenceontology.org|1.0.0"},{"name":"excludeNested","valueBoolean":false},{"name":"offset","valueInteger":0},{"name":"count","valueInteger":1000}]}}

#1093

POST https://tx.fhir.org/r4/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL378-1"}]}]}}}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1053
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:39:51 GMT
last-modified:Fri, 30 Jan 2026 18:39:51 GMT
pragma:no-cache
server:nginx
x-request-id:253-23579866

{"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:e3f6d329-c0a2-4e42-87de-93eebf4681ac","timestamp" : "2026-01-30T18:39:50.644Z","total" : 8,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://loinc.org|2.81"}],"contains" : [{"system" : "http://loinc.org","code" : "LA6683-2","display" : "Germline"},{"system" : "http://loinc.org","code" : "LA6684-0","display" : "Somatic"},{"system" : "http://loinc.org","code" : "LA10429-1","display" : "Fetal"},{"system" : "http://loinc.org","code" : "LA18194-3","display" : "Likely germline"},{"system" : "http://loinc.org","code" : "LA18195-0","display" : "Likely somatic"},{"system" : "http://loinc.org","code" : "LA18196-8","display" : "Likely fetal"},{"system" : "http://loinc.org","code" : "LA18197-6","display" : "Unknown genomic origin"},{"system" : "http://loinc.org","code" : "LA26807-0","display" : "De novo"}]}}

#1094

POST https://tx.fhir.org/r4/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL381-5"}]}]}}}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:812
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:39:52 GMT
last-modified:Fri, 30 Jan 2026 18:39:52 GMT
pragma:no-cache
server:nginx
x-request-id:253-23579888

{"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:fee582d1-69be-42dc-bbe9-7a48f3b889bd","timestamp" : "2026-01-30T18:39:51.753Z","total" : 5,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://loinc.org|2.81"}],"contains" : [{"system" : "http://loinc.org","code" : "LA6703-8","display" : "Heteroplasmic"},{"system" : "http://loinc.org","code" : "LA6704-6","display" : "Homoplasmic"},{"system" : "http://loinc.org","code" : "LA6705-3","display" : "Homozygous"},{"system" : "http://loinc.org","code" : "LA6706-1","display" : "Heterozygous"},{"system" : "http://loinc.org","code" : "LA6707-9","display" : "Hemizygous"}]}}

#1095

POST https://tx.fhir.org/r4/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL5489-1"}]}]}}}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:798
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:39:53 GMT
last-modified:Fri, 30 Jan 2026 18:39:53 GMT
pragma:no-cache
server:nginx
x-request-id:253-23579894

{"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:170c1285-17a7-467c-ae55-e63a93943ffd","timestamp" : "2026-01-30T18:39:52.113Z","total" : 5,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://loinc.org|2.81"}],"contains" : [{"system" : "http://loinc.org","code" : "LA26320-4","display" : "Maternal"},{"system" : "http://loinc.org","code" : "LA26321-2","display" : "Paternal"},{"system" : "http://loinc.org","code" : "LA26807-0","display" : "De novo"},{"system" : "http://loinc.org","code" : "LA4489-6","display" : "Unknown"},{"system" : "http://loinc.org","code" : "LA30680-5","display" : "Parental"}]}}

#1096

POST https://tx.fhir.org/r4/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL4048-6"}]}]}}}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2362
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:39:54 GMT
last-modified:Fri, 30 Jan 2026 18:39:54 GMT
pragma:no-cache
server:nginx
x-request-id:253-23579908

{"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:48c31bd0-3353-4429-b14a-53eea1c7171f","timestamp" : "2026-01-30T18:39:53.222Z","total" : 23,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://loinc.org|2.81"}],"contains" : [{"system" : "http://loinc.org","code" : "LA26398-0","display" : "Sequencing"},{"system" : "http://loinc.org","code" : "LA26399-8","display" : "Oligo aCGH"},{"system" : "http://loinc.org","code" : "LA26400-4","display" : "SNP array"},{"system" : "http://loinc.org","code" : "LA26401-2","display" : "BAC aCGH"},{"system" : "http://loinc.org","code" : "LA26402-0","display" : "Curated"},{"system" : "http://loinc.org","code" : "LA26403-8","display" : "Digital array"},{"system" : "http://loinc.org","code" : "LA26404-6","display" : "FISH"},{"system" : "http://loinc.org","code" : "LA26405-3","display" : "Gene expression array"},{"system" : "http://loinc.org","code" : "LA26406-1","display" : "Karyotyping"},{"system" : "http://loinc.org","code" : "LA26407-9","display" : "MAPH"},{"system" : "http://loinc.org","code" : "LA26408-7","display" : "MALDI-TOF"},{"system" : "http://loinc.org","code" : "LA26808-8","display" : "Merging"},{"system" : "http://loinc.org","code" : "LA26414-5","display" : "Multiple complete digestion"},{"system" : "http://loinc.org","code" : "LA26415-2","display" : "MLPA"},{"system" : "http://loinc.org","code" : "LA26417-8","display" : "Optical mapping"},{"system" : "http://loinc.org","code" : "LA26418-6","display" : "PCR"},{"system" : "http://loinc.org","code" : "LA26419-4","display" : "qPCR (real-time PCR)"},{"system" : "http://loinc.org","code" : "LA26420-2","display" : "ROMA"},{"system" : "http://loinc.org","code" : "LA26809-6","display" : "Denaturing high-pressure liquid chromatography (DHPLC)"},{"system" : "http://loinc.org","code" : "LA26810-4","display" : "DNA hybridization"},{"system" : "http://loinc.org","code" : "LA26811-2","display" : "Computational analysis"},{"system" : "http://loinc.org","code" : "LA26812-0","display" : "Single-stranded conformational polymorphism (SSCP)"},{"system" : "http://loinc.org","code" : "LA26813-8","display" : "Restriction fragment length polymorphism (RFLP)"}]}}

#1097

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$batch-validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://human-phenotype-ontology.org","code":"HP:0000006"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://human-phenotype-ontology.org","code":"HP:0000007"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://human-phenotype-ontology.org","code":"HP:0001417"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://human-phenotype-ontology.org","code":"HP:0001419"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://human-phenotype-ontology.org","code":"HP:0001423"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://human-phenotype-ontology.org","code":"HP:0001426"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://human-phenotype-ontology.org","code":"HP:0001427"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://human-phenotype-ontology.org","code":"HP:0001442"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, 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en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://human-phenotype-ontology.org","code":"HP:0003743"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://human-phenotype-ontology.org","code":"HP:0003745"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://human-phenotype-ontology.org","code":"HP:0010983"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://human-phenotype-ontology.org","code":"HP:0012274"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://human-phenotype-ontology.org","code":"HP:0012275"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://human-phenotype-ontology.org","code":"HP:0025352"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://human-phenotype-ontology.org","code":"HP:0032113"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}}]}

400
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:39:57 GMT
server:nginx
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:9501a773-aec1-4289-9f7b-cdf7b6c70b15
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:9501a773-aec1-4289-9f7b-cdf7b6c70b15
x-xss-protection:0

{"resourceType":"OperationOutcome","issue":[{"severity":"error","code":"not-supported","diagnostics":"Invalid request: The FHIR endpoint on this server does not know how to handle POST operation[ValueSet/$batch-validate-code] with parameters [[]]"},{"severity":"information","code":"informational","diagnostics":"X-Request-Id: 9501a773-aec1-4289-9f7b-cdf7b6c70b15"}]}

#1098

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$batch-validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

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400
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:39:57 GMT
server:nginx
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:c02e3e6b-31de-4be3-963f-3b887dfd84fe
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x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
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{"resourceType":"OperationOutcome","issue":[{"severity":"error","code":"not-supported","diagnostics":"Invalid request: The FHIR endpoint on this server does not know how to handle POST operation[ValueSet/$batch-validate-code] with parameters [[]]"},{"severity":"information","code":"informational","diagnostics":"X-Request-Id: c02e3e6b-31de-4be3-963f-3b887dfd84fe"}]}

#1099

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0002072"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json;charset=UTF-8
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server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:d97f48de-c0af-481e-97d0-a42d824fad63
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x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:d97f48de-c0af-481e-97d0-a42d824fad63
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0002072"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#1100

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0002072"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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server:nginx
vary:Origin
vary:Access-Control-Request-Method
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vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:5feb9ff2-1ce3-4fa9-8b73-879e3735f2d4
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x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:5feb9ff2-1ce3-4fa9-8b73-879e3735f2d4
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0002072"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#1101

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001536"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:39:59 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:3ddd23a0-5843-4fe4-93c9-acd9c17fb857
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:3ddd23a0-5843-4fe4-93c9-acd9c17fb857
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001536"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#1102

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001536"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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server:nginx
vary:Origin
vary:Access-Control-Request-Method
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vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:9a683715-b3ba-4c96-87dd-e3a2c40afcdf
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:9a683715-b3ba-4c96-87dd-e3a2c40afcdf
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001536"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#1103

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0002072"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:40:01 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:e2500b5e-5eb8-4ab8-8676-6110a63ac3b5
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x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:e2500b5e-5eb8-4ab8-8676-6110a63ac3b5
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0002072"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#1104

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001060"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json;charset=UTF-8
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server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:eaa8f5be-a673-4f0e-8dea-5c4befd0f0e1
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x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:eaa8f5be-a673-4f0e-8dea-5c4befd0f0e1
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001060"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#1105

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0002072"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json;charset=UTF-8
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server:nginx
vary:Origin
vary:Access-Control-Request-Method
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vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:a134ed8c-57ef-41e3-8f75-970b7345bca0
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x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:a134ed8c-57ef-41e3-8f75-970b7345bca0
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0002072"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#1106

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001060"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:40:02 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:b54d0004-59ec-404d-8b4d-fd416096ad6c
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:b54d0004-59ec-404d-8b4d-fd416096ad6c
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001060"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#1107

POST https://tx-nordics.fhir.org/fhir/r4/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0001060"}]}]}}}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:40:03 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:f6e3654d-a05b-44ee-992f-b672a977d6af
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:f6e3654d-a05b-44ee-992f-b672a977d6af
x-xss-protection:0

{"resourceType":"ValueSet","status":"active","expansion":{"identifier":"urn:uuid:5f7f9e50-7fac-47ff-bf43-d35104f8583b","timestamp":"2026-01-30T19:40:03+01:00","total":0,"offset":0,"parameter":[{"name":"used-codesystem","valueUri":"http://www.sequenceontology.org|1.0.0"},{"name":"version","valueUri":"http://www.sequenceontology.org|1.0.0"},{"name":"excludeNested","valueBoolean":true},{"name":"offset","valueInteger":0},{"name":"count","valueInteger":1000}]}}

#1108

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001537"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:40:05 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:19c8a7b3-9098-4af8-9349-3537b3221caa
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:19c8a7b3-9098-4af8-9349-3537b3221caa
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001537"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#1109

POST https://tx-nordics.fhir.org/fhir/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001537"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
cache-control:no-cache
content-type:application/fhir+json;charset=UTF-8
date:Fri, 30 Jan 2026 18:40:05 GMT
server:nginx
vary:Origin
vary:Access-Control-Request-Method
vary:Access-Control-Request-Headers
vary:Accept,Origin,Accept-Encoding,Accept-Language,Authorization
x-content-type-options:nosniff
x-correlation-id:b6b86b1a-da92-4e4d-8f89-52e2093d1434
x-frame-options:DENY
x-powered-by:HAPI FHIR 8.4.0 REST Server (FHIR Server; FHIR 4.0.1/R4)
x-request-id:b6b86b1a-da92-4e4d-8f89-52e2093d1434
x-xss-protection:0

{"resourceType":"Parameters","parameter":[{"name":"result","valueBoolean":false},{"name":"code","valueCode":"SO:0001537"},{"name":"system","valueUri":"http://www.sequenceontology.org"},{"name":"issues","resource":{"resourceType":"OperationOutcome","issue":[{"severity":"warning","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"vs-invalid"}],"text":"Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}},{"severity":"error","code":"not-found","details":{"coding":[{"system":"http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code":"not-found"}],"text":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location":["Coding.system"],"expression":["Coding.system"]}]}},{"name":"x-caused-by-unknown-system","valueCanonical":"http://www.sequenceontology.org"},{"name":"message","valueString":"A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set '' because the code system http://www.sequenceontology.org was not found"}]}

#1110

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"93044-6"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:752
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:40:16 GMT
last-modified:Fri, 30 Jan 2026 18:40:16 GMT
pragma:no-cache
server:nginx
x-request-id:253-23580243

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "93044-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Level of evidence"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#93044-6 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#93044-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1111

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"53037-8"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:780
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:40:16 GMT
last-modified:Fri, 30 Jan 2026 18:40:16 GMT
pragma:no-cache
server:nginx
x-request-id:253-23580244

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "53037-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic variation clinical significance [Imp]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#53037-8 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#53037-8\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1112

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81259-4"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:755
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:40:16 GMT
last-modified:Fri, 30 Jan 2026 18:40:16 GMT
pragma:no-cache
server:nginx
x-request-id:253-23580247

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81259-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Associated phenotype"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81259-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81259-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1113

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48018-6"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:752
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:40:17 GMT
last-modified:Fri, 30 Jan 2026 18:40:17 GMT
pragma:no-cache
server:nginx
x-request-id:253-23580249

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48018-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Gene studied [ID]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48018-6 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48018-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1114

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48001-2"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:768
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:40:17 GMT
last-modified:Fri, 30 Jan 2026 18:40:17 GMT
pragma:no-cache
server:nginx
x-request-id:253-23580251

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48001-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Cytogenetic (chromosome) location"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48001-2 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48001-2\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1115

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"62374-4"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:776
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:40:17 GMT
last-modified:Fri, 30 Jan 2026 18:40:17 GMT
pragma:no-cache
server:nginx
x-request-id:253-23580253

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "62374-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Human reference sequence assembly version"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#62374-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#62374-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1116

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48000-4"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:806
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:40:17 GMT
last-modified:Fri, 30 Jan 2026 18:40:17 GMT
pragma:no-cache
server:nginx
x-request-id:253-23580254

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48000-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Chromosome [Identifier] in Blood or Tissue by Molecular genetics method"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48000-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48000-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1117

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"92821-8"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:766
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:40:17 GMT
last-modified:Fri, 30 Jan 2026 18:40:17 GMT
pragma:no-cache
server:nginx
x-request-id:253-23580255

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "92821-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic frequency in Population"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#92821-8 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#92821-8\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1118

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"84413-4"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:756
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:40:17 GMT
last-modified:Fri, 30 Jan 2026 18:40:17 GMT
pragma:no-cache
server:nginx
x-request-id:253-23580259

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "84413-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genotype display name"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#84413-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#84413-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1119

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"84414-2"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:749
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:40:17 GMT
last-modified:Fri, 30 Jan 2026 18:40:17 GMT
pragma:no-cache
server:nginx
x-request-id:253-23580263

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "84414-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Haplotype name"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#84414-2 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#84414-2\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1120

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48004-6"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:754
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:40:17 GMT
last-modified:Fri, 30 Jan 2026 18:40:17 GMT
pragma:no-cache
server:nginx
x-request-id:253-23580266

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48004-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "DNA change (c.HGVS)"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48004-6 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48004-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1121

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"51958-7"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:769
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:40:17 GMT
last-modified:Fri, 30 Jan 2026 18:40:17 GMT
pragma:no-cache
server:nginx
x-request-id:253-23580268

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51958-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Transcript reference sequence [ID]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#51958-7 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#51958-7\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1122

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48005-3"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:760
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:40:18 GMT
last-modified:Fri, 30 Jan 2026 18:40:18 GMT
pragma:no-cache
server:nginx
x-request-id:253-23580270

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48005-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Amino acid change (pHGVS)"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48005-3 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48005-3\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1123

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"82120-7"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:748
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:40:18 GMT
last-modified:Fri, 30 Jan 2026 18:40:18 GMT
pragma:no-cache
server:nginx
x-request-id:253-23580271

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82120-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic phase"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#82120-7 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#82120-7\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1124

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"51963-7"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:759
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:40:18 GMT
last-modified:Fri, 30 Jan 2026 18:40:18 GMT
pragma:no-cache
server:nginx
x-request-id:253-23580274

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51963-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Medication assessed [ID]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#51963-7 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#51963-7\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1125

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"69548-6"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:761
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:40:18 GMT
last-modified:Fri, 30 Jan 2026 18:40:18 GMT
pragma:no-cache
server:nginx
x-request-id:253-23580275

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69548-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic variant assessment"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#69548-6 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#69548-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1126

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81290-9"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:761
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:40:18 GMT
last-modified:Fri, 30 Jan 2026 18:40:18 GMT
pragma:no-cache
server:nginx
x-request-id:253-23580277

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81290-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic DNA change (gHGVS)"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81290-9 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81290-9\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1127

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81291-7"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:747
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:40:18 GMT
last-modified:Fri, 30 Jan 2026 18:40:18 GMT
pragma:no-cache
server:nginx
x-request-id:253-23580279

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81291-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Variant ISCN"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81291-7 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81291-7\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1128

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48013-7"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:766
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:40:18 GMT
last-modified:Fri, 30 Jan 2026 18:40:18 GMT
pragma:no-cache
server:nginx
x-request-id:253-23580282

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48013-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic reference sequence [ID]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"()\"\r\n16 0    : 0ms  : Validate \"[http://loinc.org#48013-7 (\"\")]\"\r\n16 0    : 0ms  : Check \"http://loinc.org#48013-7\"\r\n16 0    : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1129

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81254-5"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:759
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:40:18 GMT
last-modified:Fri, 30 Jan 2026 18:40:18 GMT
pragma:no-cache
server:nginx
x-request-id:253-23580284

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81254-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic allele start-end"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81254-5 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81254-5\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1130

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81302-2"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:773
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:40:18 GMT
last-modified:Fri, 30 Jan 2026 18:40:18 GMT
pragma:no-cache
server:nginx
x-request-id:253-23580285

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81302-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Structural variant inner start and end"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81302-2 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81302-2\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1131

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81301-4"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:773
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:40:19 GMT
last-modified:Fri, 30 Jan 2026 18:40:19 GMT
pragma:no-cache
server:nginx
x-request-id:253-23580288

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81301-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Structural variant outer start and end"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81301-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81301-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1132

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"92822-6"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:767
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:40:19 GMT
last-modified:Fri, 30 Jan 2026 18:40:19 GMT
pragma:no-cache
server:nginx
x-request-id:253-23580289

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "92822-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic coordinate system [Type]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#92822-6 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#92822-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1133

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"69547-8"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:758
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:40:19 GMT
last-modified:Fri, 30 Jan 2026 18:40:19 GMT
pragma:no-cache
server:nginx
x-request-id:253-23580291

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69547-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic ref allele [ID]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#69547-8 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#69547-8\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1134

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"69551-0"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:758
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:40:19 GMT
last-modified:Fri, 30 Jan 2026 18:40:19 GMT
pragma:no-cache
server:nginx
x-request-id:253-23580293

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69551-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic alt allele [ID]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#69551-0 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#69551-0\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1135

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48019-4"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:750
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:40:19 GMT
last-modified:Fri, 30 Jan 2026 18:40:19 GMT
pragma:no-cache
server:nginx
x-request-id:253-23580296

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48019-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "DNA change type"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48019-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48019-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1136

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48002-0"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:762
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:40:19 GMT
last-modified:Fri, 30 Jan 2026 18:40:19 GMT
pragma:no-cache
server:nginx
x-request-id:253-23580300

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48002-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic source class [Type]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48002-0 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48002-0\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1137

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81258-6"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:773
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:40:19 GMT
last-modified:Fri, 30 Jan 2026 18:40:19 GMT
pragma:no-cache
server:nginx
x-request-id:253-23580301

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81258-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Sample variant allelic frequency [NFr]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81258-6 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81258-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1138

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"82121-5"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:753
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:40:19 GMT
last-modified:Fri, 30 Jan 2026 18:40:19 GMT
pragma:no-cache
server:nginx
x-request-id:253-23580302

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82121-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic read depth"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#82121-5 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#82121-5\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1139

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"53034-5"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:748
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:40:19 GMT
last-modified:Fri, 30 Jan 2026 18:40:19 GMT
pragma:no-cache
server:nginx
x-request-id:253-23580305

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "53034-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic state"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#53034-5 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#53034-5\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1140

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"94186-4"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:776
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:40:20 GMT
last-modified:Fri, 30 Jan 2026 18:40:20 GMT
pragma:no-cache
server:nginx
x-request-id:253-23580307

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "94186-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Origin of germline genetic variant [Type]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#94186-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#94186-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1141

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"82309-6"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:765
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:40:20 GMT
last-modified:Fri, 30 Jan 2026 18:40:20 GMT
pragma:no-cache
server:nginx
x-request-id:253-23580308

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82309-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Basis for allelic phase [Type]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#82309-6 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#82309-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1142

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81252-9"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:759
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:40:20 GMT
last-modified:Fri, 30 Jan 2026 18:40:20 GMT
pragma:no-cache
server:nginx
x-request-id:253-23580310

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81252-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Discrete genetic variant"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81252-9 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81252-9\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1143

POST https://tx.fhir.org/r4/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=4.0
Content-Type: application/fhir+json; fhirVersion=4.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"82155-3"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"65d026ce-63c0-43fb-93e3-899eec9d63f6"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:773
content-type:application/fhir+json
date:Fri, 30 Jan 2026 18:40:20 GMT
last-modified:Fri, 30 Jan 2026 18:40:20 GMT
pragma:no-cache
server:nginx
x-request-id:253-23580312

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82155-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic structural variant copy number"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#82155-3 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#82155-3\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}