Intersection of http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/pharmgkb-evidence-level-custom-cs and http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/pharmgkb-evidence-level-custom-cs

This is the CodeSystem that contains codes in both PharmGKB Evidence Level Example Codes (http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/pharmgkb-evidence-level-custom-cs) and PharmGKB Evidence Level Example Codes (http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/pharmgkb-evidence-level-custom-cs).

Structure

Generated Narrative: CodeSystem 6ce80508-20a6-4134-be9f-785d1a43c4a2-27

This code system http://hl7.org/fhir/comparison/CodeSystem/6ce80508-20a6-4134-be9f-785d1a43c4a2-27 defines codes, but no codes are represented here

CodeDisplayDefinition
1A PGKB 1AHigh level of evidence. Supported by a guideline or FDA label with variant specific prescribing guidance. Additionally, supported by at least one publication.
1B PGKB 1BHigh level of evidence. But, NOT supported by a guideline or FDA label with variant specific prescribing guidance. Additionally, supported by at least one publication.
2A PGKB 2AModerate level of evidence. Supported by being a KNOWN pharmacogene on https://www.pharmgkb.org/vips. Also, found in multiple studies but may have a minority of studies that did not support the majority opinion. Supported by at least two indpendent publications.
2B PGKB 2BModerate level of evidence. NOT in the list of very important, KNOWN pharmacogenes. Found in multiple studies but may have a minority of studies that did not support the majority opinion. Supported by at least two indpendent publications.
3 PGKB 3Low-level of evidence. Where either the assocation is based on a single study, failed to be reproduced, or preliminary evidence.
4 PGKB 4The evidence does not support an association between the variant and the drug phenotype. (negative)