Genomics Reporting Implementation Guide
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Genomics Reporting Implementation Guide, published by HL7 International / Clinical Genomics. This guide is not an authorized publication; it is the continuous build for version 4.0.0-cibuild built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/genomics-reporting/ and changes regularly. See the Directory of published versions

Resource Profile: Variant - TTL Profile

Page standards status: Trial-use Maturity Level: 2

TTL representation of the variant resource profile.

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@prefix fhir: <http://hl7.org/fhir/> .
@prefix loinc: <http://loinc.org/rdf#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

# - resource -------------------------------------------------------------------

<http://hl7.org/fhir/StructureDefinition/variant> a fhir:StructureDefinition ;
  fhir:nodeRole fhir:treeRoot ;
  fhir:Resource.id [ fhir:value "variant"] ;
  fhir:DomainResource.text [
     fhir:Narrative.status [ fhir:value "extensions" ] ;
     fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: StructureDefinition variant</b></p><a name=\"variant\"> </a><a name=\"hcvariant\"> </a><table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" class=\"xhtTableBorder0\"><tr class=\"xhtRowBorder1\"><th scope=\"col\" style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views\" title=\"The logical name of the element\">Name</a></th><th scope=\"col\" style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views\" title=\"Information about the use of the element\">Flags</a></th><th scope=\"col\" style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views\" title=\"Minimum and Maximum # of times the element can appear in the instance\">Card.</a></th><th scope=\"col\" style=\"; width: 100px\" class=\"hierarchy xhtCellBorder0\"><a href=\"https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views\" title=\"Reference to the type of the element\">Type</a></th><th scope=\"col\" style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views\" title=\"Additional information about the element\">Description &amp; Constraints</a><span style=\"float: right\"><a href=\"https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views\" title=\"Legend for this format\"><img src=\"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAABmJLR0QA/wD/AP+gvaeTAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3goXBCwdPqAP0wAAAldJREFUOMuNk0tIlFEYhp9z/vE2jHkhxXA0zJCMitrUQlq4lnSltEqCFhFG2MJFhIvIFpkEWaTQqjaWZRkp0g26URZkTpbaaOJkDqk10szoODP//7XIMUe0elcfnPd9zsfLOYplGrpRwZaqTtw3K7PtGem7Q6FoidbGgqHVy/HRb669R+56zx7eRV1L31JGxYbBtjKK93cxeqfyQHbehkZbUkK20goELEuIzEd+dHS+qz/Y8PTSif0FnGkbiwcAjHaU1+QWOptFiyCLp/LnKptpqIuXHx6rbR26kJcBX3yLgBfnd7CxwJmflpP2wUg0HIAoUUpZBmKzELGWcN8nAr6Gpu7tLU/CkwAaoKTWRSQyt89Q8w6J+oVQkKnBoblH7V0PPvUOvDYXfopE/SJmALsxnVm6LbkotrUtNowMeIrVrBcBpaMmdS0j9df7abpSuy7HWehwJdt1lhVwi/J58U5beXGAF6c3UXLycw1wdFklArBn87xdh0ZsZtArghBdAA3+OEDVubG4UEzP6x1FOWneHh2VDAHBAt80IbdXDcesNoCvs3E5AFyNSU5nbrDPZpcUEQQTFZiEVx+51fxMhhyJEAgvlriadIJZZksRuwBYMOPBbO3hePVVqgEJhFeUuFLhIPkRP6BQLIBrmMenujm/3g4zc398awIe90Zb5A1vREALqneMcYgP/xVQWlG+Ncu5vgwwlaUNx+3799rfe96u9K0JSDXcOzOTJg4B6IgmXfsygc7/Bvg9g9E58/cDVmGIBOP/zT8Bz1zqWqpbXIsd0O9hajXfL6u4BaOS6SeWAAAAAElFTkSuQmCC\" alt=\"doco\" style=\"background-color: inherit\"/></a></span></th></tr><tr class=\"xhtRowBorder0 xhtRowEven\"><td style=\"background-image: url(tbl_bck1.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_resource.png\" alt=\"\" style=\"background-color: white; background-color: inherit\" title=\"Resource\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation\">Observation</a><a name=\"Observation\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"><span class=\"xhtPieceDeEmphasized\">0</span><span class=\"xhtPieceDeEmphasized\">..</span><span class=\"xhtPieceDeEmphasized\">*</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"StructureDefinition-finding.html\">GenomicFinding</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">Variant</td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowOdd\"><td style=\"background-image: url(tbl_bck10.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\"\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.code\">code</a><a name=\"Observation.code\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"><span class=\"xhtPieceDeEmphasized\">1</span><span class=\"xhtPieceDeEmphasized\">..</span><span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\" class=\"xhtPieceDeEmphasized\">CodeableConcept</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">69548-6<br/><span class=\"xhtPieceBold\">Required Pattern: </span><div><pre class=\"json\"><code>{\n  \"coding\" : [\n    {\n      \"system\" : \"http://loinc.org\",\n      \"code\" : <span title=\"Genetic variant assessment\">\"69548-6\"</span>\n    }\n  ]\n}</code></pre></div></td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowEven\"><td style=\"background-image: url(tbl_bck13.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice.png\" alt=\"\" style=\"background-color: white; background-color: inherit\" title=\"Slice Definition\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.value[x]\" class=\"xhtPieceItalic\">Slices for value[x]</a><a name=\"Observation.value_x_\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"><span class=\"xhtPieceItalic\"/><span class=\"xhtPieceItalic xhtPieceDeEmphasized\">0</span><span class=\"xhtPieceItalic xhtPieceDeEmphasized\">..</span><span class=\"xhtPieceItalic xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#Quantity\" class=\"xhtPieceItalic xhtPieceDeEmphasized\">Quantity</a><span class=\"xhtPieceItalic xhtPieceDeEmphasized\">, </span><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\" class=\"xhtPieceItalic xhtPieceDeEmphasized\">CodeableConcept</a><span class=\"xhtPieceItalic xhtPieceDeEmphasized\">, </span><a href=\"http://hl7.org/fhir/R4/datatypes.html#string\" class=\"xhtPieceItalic xhtPieceDeEmphasized\">string</a><span class=\"xhtPieceItalic xhtPieceDeEmphasized\">, </span><a href=\"http://hl7.org/fhir/R4/datatypes.html#boolean\" class=\"xhtPieceItalic xhtPieceDeEmphasized\">boolean</a><span class=\"xhtPieceItalic xhtPieceDeEmphasized\">, </span><a href=\"http://hl7.org/fhir/R4/datatypes.html#integer\" class=\"xhtPieceItalic xhtPieceDeEmphasized\">integer</a><span class=\"xhtPieceItalic xhtPieceDeEmphasized\">, </span><a href=\"http://hl7.org/fhir/R4/datatypes.html#Range\" class=\"xhtPieceItalic xhtPieceDeEmphasized\">Range</a><span class=\"xhtPieceItalic xhtPieceDeEmphasized\">, </span><a href=\"http://hl7.org/fhir/R4/datatypes.html#Ratio\" class=\"xhtPieceItalic xhtPieceDeEmphasized\">Ratio</a><span class=\"xhtPieceItalic xhtPieceDeEmphasized\">, </span><a href=\"http://hl7.org/fhir/R4/datatypes.html#SampledData\" class=\"xhtPieceItalic xhtPieceDeEmphasized\">SampledData</a><span class=\"xhtPieceItalic xhtPieceDeEmphasized\">, </span><a href=\"http://hl7.org/fhir/R4/datatypes.html#time\" class=\"xhtPieceItalic xhtPieceDeEmphasized\">time</a><span class=\"xhtPieceItalic xhtPieceDeEmphasized\">, </span><a href=\"http://hl7.org/fhir/R4/datatypes.html#dateTime\" class=\"xhtPieceItalic xhtPieceDeEmphasized\">dateTime</a><span class=\"xhtPieceItalic xhtPieceDeEmphasized\">, </span><a href=\"http://hl7.org/fhir/R4/datatypes.html#Period\" class=\"xhtPieceItalic xhtPieceDeEmphasized\">Period</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><span class=\"xhtPieceItalic xhtPieceDeEmphasized\">Actual result</span><br class=\"xhtPieceItalic\"/><span class=\"xhtPieceBold xhtPieceItalic\">Slice: </span><span class=\"xhtPieceItalic\">Unordered, Open by type:$this</span><br class=\"xhtPieceItalic\"/><span class=\"xhtPieceBold xhtPieceItalic\">Slicing Note: </span><span class=\"xhtPieceItalic\">Other type slices that contain no new information are not shown in this view</span></td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowOdd\"><td style=\"background-image: url(tbl_bck124.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\"\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for value[x].</span><a href=\"StructureDefinition-variant-definitions.html#Observation.value[x]:valueCodeableConcept\" title=\"Slice valueCodeableConcept: The presence or absence of the variant described in the components. If not searching for specific variations and merely reporting what's found, the profile's value should be set to 'Present'.\">value[x]:valueCodeableConcept</a><a name=\"Observation.value_x_:valueCodeableConcept\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\">0..1</td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">Indeterminate | No call | Present | Absent.<br class=\"binding\"/><span class=\"xhtPieceBold binding\">Binding: </span><a href=\"https://loinc.org/LL1971-2/\" class=\"binding\">LOINC Answer List LL1971-2</a><span class=\"binding\"> (</span><a href=\"http://hl7.org/fhir/R4/terminologies.html#required\" title=\"To be conformant, the concept in this element SHALL be from the specified value set.\" class=\"binding\">required</a><span class=\"binding\">)</span></td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowEven\"><td style=\"background-image: url(tbl_bck10.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\"\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.method\">method</a><a name=\"Observation.method\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"><span class=\"xhtPieceDeEmphasized\">0</span><span class=\"xhtPieceDeEmphasized\">..</span><span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\" class=\"xhtPieceDeEmphasized\">CodeableConcept</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">Sequencing | SNP array | PCR | Computational analysis | ...<br class=\"binding\"/><span class=\"xhtPieceBold binding\">Binding: </span><a href=\"https://loinc.org/LL4048-6/\" class=\"binding\">LOINC Answer List LL4048-6</a><span class=\"binding\"> (</span><a href=\"http://hl7.org/fhir/R4/terminologies.html#extensible\" title=\"To be conformant, the concept in this element SHALL be from the specified value set if any of the codes within the value set can apply to the concept being communicated.  If the value set does not cover the concept (based on human review), alternate codings (or, data type allowing, text) may be included instead.\" class=\"binding\">extensible</a><span class=\"binding\">)</span></td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowOdd\"><td style=\"background-image: url(tbl_bck03.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice.png\" alt=\"\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Slice Definition\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.</span>Slices for component<a name=\"Observation.component\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\">Content/Rules for all slices</td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowEven\"><td style=\"background-image: url(tbl_bck035.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\"\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:representative-coding-hgvs\" title=\"Slice representative-coding-hgvs: Human Genome Variation Society (HGVS) nomenclature for a single DNA marker. The use of the nomenclature must be extended to describe non-variations (aka. wild types) see samples for wild type examples.\">component:representative-coding-hgvs</a><a name=\"Observation.component:representative-coding-hgvs\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\">0..1</td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\" class=\"xhtPieceDeEmphasized\">BackboneElement</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">DNA change (c.HGVS)</td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowOdd\"><td style=\"background-image: url(tbl_bck0350.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\"\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:representative-coding-hgvs.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:representative-coding-hgvs.code\">code</a><a name=\"Observation.component:representative-coding-hgvs.code\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"><span class=\"xhtPieceDeEmphasized\">1</span><span class=\"xhtPieceDeEmphasized\">..</span><span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\" class=\"xhtPieceDeEmphasized\">CodeableConcept</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">48004-6<br/><span class=\"xhtPieceBold\">Required Pattern: </span><div><pre class=\"json\"><code>{\n  \"coding\" : [\n    {\n      \"system\" : \"http://loinc.org\",\n      \"code\" : <span title=\"DNA change (c.HGVS)\">\"48004-6\"</span>\n    }\n  ]\n}</code></pre></div></td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowEven\"><td style=\"background-image: url(tbl_bck0340.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\"\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:representative-coding-hgvs.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:representative-coding-hgvs.value[x]\">value[x]</a><a name=\"Observation.component:representative-coding-hgvs.value_x_\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\">1..<span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">A valid HGVS-formatted 'c.' string, e.g. NM_005228.5:c.2369C&gt;T.<br class=\"binding\"/><span class=\"xhtPieceBold binding\">Binding: </span><a href=\"ValueSet-hgvs-vs.html\" title=\"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs\" class=\"binding\">Human Genome Variation Society (HGVS) Nomenclature</a><span class=\"binding\"> (</span><a href=\"http://hl7.org/fhir/R4/terminologies.html#required\" title=\"To be conformant, the concept in this element SHALL be from the specified value set.\" class=\"binding\">required</a><span class=\"binding\">)</span></td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowOdd\"><td style=\"background-image: url(tbl_bck035.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\"\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:genomic-hgvs\" title=\"Slice genomic-hgvs: Description of the genomic (gDNA) sequence change using a valid HGVS-formatted string.\">component:genomic-hgvs</a><a name=\"Observation.component:genomic-hgvs\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\">0..1</td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\" class=\"xhtPieceDeEmphasized\">BackboneElement</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">Genomic (gDNA) Change - gHGVS</td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowEven\"><td style=\"background-image: url(tbl_bck0350.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\"\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:genomic-hgvs.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:genomic-hgvs.code\">code</a><a name=\"Observation.component:genomic-hgvs.code\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"><span class=\"xhtPieceDeEmphasized\">1</span><span class=\"xhtPieceDeEmphasized\">..</span><span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\" class=\"xhtPieceDeEmphasized\">CodeableConcept</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">81290-9<br/><span class=\"xhtPieceBold\">Required Pattern: </span><div><pre class=\"json\"><code>{\n  \"coding\" : [\n    {\n      \"system\" : \"http://loinc.org\",\n      \"code\" : <span title=\"Genomic DNA change (gHGVS)\">\"81290-9\"</span>\n    }\n  ]\n}</code></pre></div></td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowOdd\"><td style=\"background-image: url(tbl_bck0340.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\"\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:genomic-hgvs.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:genomic-hgvs.value[x]\">value[x]</a><a name=\"Observation.component:genomic-hgvs.value_x_\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\">1..<span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">A valid HGVS-formatted 'g.' string, e.g. NC_000016.9:g.2124200_2138612dup<br class=\"binding\"/><span class=\"xhtPieceBold binding\">Binding: </span><a href=\"ValueSet-hgvs-vs.html\" title=\"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs\" class=\"binding\">Human Genome Variation Society (HGVS) Nomenclature</a><span class=\"binding\"> (</span><a href=\"http://hl7.org/fhir/R4/terminologies.html#required\" title=\"To be conformant, the concept in this element SHALL be from the specified value set.\" class=\"binding\">required</a><span class=\"binding\">)</span></td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowEven\"><td style=\"background-image: url(tbl_bck035.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\"\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:cytogenomic-nomenclature\" title=\"Slice cytogenomic-nomenclature: Fully describes a variant with a single code. Typically a large variant such as a mosaic, abnormal chromosome numbers, etc.\">component:cytogenomic-nomenclature</a><a name=\"Observation.component:cytogenomic-nomenclature\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\">0..1</td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\" class=\"xhtPieceDeEmphasized\">BackboneElement</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">Cytogenomic Nomenclature (ISCN)</td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowOdd\"><td style=\"background-image: url(tbl_bck0350.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\"\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:cytogenomic-nomenclature.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:cytogenomic-nomenclature.code\">code</a><a name=\"Observation.component:cytogenomic-nomenclature.code\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"><span class=\"xhtPieceDeEmphasized\">1</span><span class=\"xhtPieceDeEmphasized\">..</span><span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\" class=\"xhtPieceDeEmphasized\">CodeableConcept</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">81291-7<br/><span class=\"xhtPieceBold\">Required Pattern: </span><div><pre class=\"json\"><code>{\n  \"coding\" : [\n    {\n      \"system\" : \"http://loinc.org\",\n      \"code\" : <span title=\"Variant ISCN\">\"81291-7\"</span>\n    }\n  ]\n}</code></pre></div></td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowEven\"><td style=\"background-image: url(tbl_bck0340.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\"\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:cytogenomic-nomenclature.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:cytogenomic-nomenclature.value[x]\">value[x]</a><a name=\"Observation.component:cytogenomic-nomenclature.value_x_\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\">1..<span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><span class=\"xhtPieceDeEmphasized\">Actual component result</span><br class=\"binding\"/><span class=\"xhtPieceBold binding\">Binding Description: </span><span class=\"binding\"> (</span><a href=\"http://hl7.org/fhir/R4/terminologies.html#example\" title=\"Instances are not expected or even encouraged to draw from the specified value set.  The value set merely provides examples of the types of concepts intended to be included.\" class=\"binding\">example</a><span class=\"binding\">)</span><span class=\"binding\">: </span><span class=\"binding\">Binding not yet defined</span></td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowOdd\"><td style=\"background-image: url(tbl_bck035.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\"\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:genomic-ref-seq\" title=\"Slice genomic-ref-seq: ID of the genomic reference sequence, which includes transcribed and non transcribed stretches\">component:genomic-ref-seq</a><a name=\"Observation.component:genomic-ref-seq\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\">0..1</td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\" class=\"xhtPieceDeEmphasized\">BackboneElement</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">Genomic Reference Sequence</td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowEven\"><td style=\"background-image: url(tbl_bck0350.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\"\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:genomic-ref-seq.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:genomic-ref-seq.code\">code</a><a name=\"Observation.component:genomic-ref-seq.code\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"><span class=\"xhtPieceDeEmphasized\">1</span><span class=\"xhtPieceDeEmphasized\">..</span><span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\" class=\"xhtPieceDeEmphasized\">CodeableConcept</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">48013-7<br/><span class=\"xhtPieceBold\">Required Pattern: </span><div><pre class=\"json\"><code>{\n  \"coding\" : [\n    {\n      \"system\" : \"http://loinc.org\",\n      \"code\" : <span title=\"Genomic reference sequence [ID]\">\"48013-7\"</span>\n    }\n  ]\n}</code></pre></div></td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowOdd\"><td style=\"background-image: url(tbl_bck0340.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\"\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:genomic-ref-seq.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:genomic-ref-seq.value[x]\">value[x]</a><a name=\"Observation.component:genomic-ref-seq.value_x_\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\">1..<span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">Versioned genomic reference sequence identifier<br class=\"binding\"/><span class=\"xhtPieceBold binding\">Binding Description: </span><span class=\"binding\"> (</span><a href=\"http://hl7.org/fhir/R4/terminologies.html#example\" title=\"Instances are not expected or even encouraged to draw from the specified value set.  The value set merely provides examples of the types of concepts intended to be included.\" class=\"binding\">example</a><span class=\"binding\">)</span><span class=\"binding\">: </span><span class=\"binding\">Multiple bindings acceptable (NCBI or LRG)</span></td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowEven\"><td style=\"background-image: url(tbl_bck035.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\"\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:representative-protein-ref-seq\" title=\"Slice representative-protein-ref-seq: ID of the protein reference sequence, which includes transcribed and non transcribed stretches. It covers the entire protein described.\">component:representative-protein-ref-seq</a><a name=\"Observation.component:representative-protein-ref-seq\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\">0..1</td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\" class=\"xhtPieceDeEmphasized\">BackboneElement</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">Protein Reference Sequence</td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowOdd\"><td style=\"background-image: url(tbl_bck0350.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\"\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:representative-protein-ref-seq.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:representative-protein-ref-seq.code\">code</a><a name=\"Observation.component:representative-protein-ref-seq.code\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"><span class=\"xhtPieceDeEmphasized\">1</span><span class=\"xhtPieceDeEmphasized\">..</span><span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\" class=\"xhtPieceDeEmphasized\">CodeableConcept</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">protein-ref-seq<br/><span class=\"xhtPieceBold\">Required Pattern: </span><div><pre class=\"json\"><code>{\n  \"coding\" : [\n    {\n      \"system\" : \"http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs\",\n      \"code\" : <span title=\"Protein Reference Sequence\">\"protein-ref-seq\"</span>\n    }\n  ]\n}</code></pre></div></td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowEven\"><td style=\"background-image: url(tbl_bck0340.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\"\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:representative-protein-ref-seq.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:representative-protein-ref-seq.value[x]\">value[x]</a><a name=\"Observation.component:representative-protein-ref-seq.value_x_\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\">1..<span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">Versioned protein reference sequence identifier<br class=\"binding\"/><span class=\"xhtPieceBold binding\">Binding Description: </span><span class=\"binding\"> (</span><a href=\"http://hl7.org/fhir/R4/terminologies.html#example\" title=\"Instances are not expected or even encouraged to draw from the specified value set.  The value set merely provides examples of the types of concepts intended to be included.\" class=\"binding\">example</a><span class=\"binding\">)</span><span class=\"binding\">: </span><span class=\"binding\">Multiple bindings acceptable (NCBI or LRG)</span></td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowOdd\"><td style=\"background-image: url(tbl_bck035.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\"\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:representative-transcript-ref-seq\" title=\"Slice representative-transcript-ref-seq: NCBI's RefSeq ('NM_...'), Ensembl ('ENST...'), and LRG ('LRG...' plus 't1' to indicate transcript)\">component:representative-transcript-ref-seq</a><a name=\"Observation.component:representative-transcript-ref-seq\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\">0..1</td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\" class=\"xhtPieceDeEmphasized\">BackboneElement</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">Reference Transcript</td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowEven\"><td style=\"background-image: url(tbl_bck0350.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\"\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:representative-transcript-ref-seq.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:representative-transcript-ref-seq.code\">code</a><a name=\"Observation.component:representative-transcript-ref-seq.code\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"><span class=\"xhtPieceDeEmphasized\">1</span><span class=\"xhtPieceDeEmphasized\">..</span><span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\" class=\"xhtPieceDeEmphasized\">CodeableConcept</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">51958-7<br/><span class=\"xhtPieceBold\">Required Pattern: </span><div><pre class=\"json\"><code>{\n  \"coding\" : [\n    {\n      \"system\" : \"http://loinc.org\",\n      \"code\" : <span title=\"Transcript reference sequence [ID]\">\"51958-7\"</span>\n    }\n  ]\n}</code></pre></div></td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowOdd\"><td style=\"background-image: url(tbl_bck0340.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\"\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:representative-transcript-ref-seq.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:representative-transcript-ref-seq.value[x]\">value[x]</a><a name=\"Observation.component:representative-transcript-ref-seq.value_x_\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\">1..<span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">Versioned transcript reference sequence identifier<br class=\"binding\"/><span class=\"xhtPieceBold binding\">Binding Description: </span><span class=\"binding\"> (</span><a href=\"http://hl7.org/fhir/R4/terminologies.html#example\" title=\"Instances are not expected or even encouraged to draw from the specified value set.  The value set merely provides examples of the types of concepts intended to be included.\" class=\"binding\">example</a><span class=\"binding\">)</span><span class=\"binding\">: </span><span class=\"binding\">Multiple bindings acceptable (NCBI or LRG)</span></td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowEven\"><td style=\"background-image: url(tbl_bck035.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\"\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:exact-start-end\" title=\"Slice exact-start-end: The exact integer-based genomic coordinates of the start and end of the variant region.\">component:exact-start-end</a><a name=\"Observation.component:exact-start-end\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\">0..1</td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\" class=\"xhtPieceDeEmphasized\">BackboneElement</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">Exact Start-End</td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowOdd\"><td style=\"background-image: url(tbl_bck0350.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\"\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:exact-start-end.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:exact-start-end.code\">code</a><a name=\"Observation.component:exact-start-end.code\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"><span class=\"xhtPieceDeEmphasized\">1</span><span class=\"xhtPieceDeEmphasized\">..</span><span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\" class=\"xhtPieceDeEmphasized\">CodeableConcept</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">81254-5<br/><span class=\"xhtPieceBold\">Required Pattern: </span><div><pre class=\"json\"><code>{\n  \"coding\" : [\n    {\n      \"system\" : \"http://loinc.org\",\n      \"code\" : <span title=\"Genomic allele start-end\">\"81254-5\"</span>\n    }\n  ]\n}</code></pre></div></td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowEven\"><td style=\"background-image: url(tbl_bck0340.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\"\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:exact-start-end.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:exact-start-end.value[x]\">value[x]</a><a name=\"Observation.component:exact-start-end.value_x_\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"><span class=\"xhtPieceDeEmphasized\">0</span><span class=\"xhtPieceDeEmphasized\">..</span><span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#Range\">Range</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">Range in question. 'High' can be omitted for single nucleotide variants.</td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowOdd\"><td style=\"background-image: url(tbl_bck035.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\"\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:inner-start-end\" title=\"Slice inner-start-end: The genomic coordinates of the narrowest genomic range in which the variant might reside. Used when the exact boundaries of the variant are not clear.\">component:inner-start-end</a><a name=\"Observation.component:inner-start-end\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\">0..1</td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\" class=\"xhtPieceDeEmphasized\">BackboneElement</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">Inner Start-End</td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowEven\"><td style=\"background-image: url(tbl_bck0350.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\"\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:inner-start-end.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:inner-start-end.code\">code</a><a name=\"Observation.component:inner-start-end.code\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"><span class=\"xhtPieceDeEmphasized\">1</span><span class=\"xhtPieceDeEmphasized\">..</span><span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\" class=\"xhtPieceDeEmphasized\">CodeableConcept</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">81302-2<br/><span class=\"xhtPieceBold\">Required Pattern: </span><div><pre class=\"json\"><code>{\n  \"coding\" : [\n    {\n      \"system\" : \"http://loinc.org\",\n      \"code\" : <span title=\"Structural variant inner start and end\">\"81302-2\"</span>\n    }\n  ]\n}</code></pre></div></td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowOdd\"><td style=\"background-image: url(tbl_bck0340.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\"\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:inner-start-end.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:inner-start-end.value[x]\">value[x]</a><a name=\"Observation.component:inner-start-end.value_x_\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"><span class=\"xhtPieceDeEmphasized\">0</span><span class=\"xhtPieceDeEmphasized\">..</span><span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#Range\">Range</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">Imprecise variant inner-bounding range</td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowEven\"><td style=\"background-image: url(tbl_bck035.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\"\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:outer-start-end\" title=\"Slice outer-start-end: The genomic coordinates of the widest genomic range in which the variant might reside. Used when the exact boundaries of the variant are not clear.\">component:outer-start-end</a><a name=\"Observation.component:outer-start-end\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\">0..1</td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\" class=\"xhtPieceDeEmphasized\">BackboneElement</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">Outer Start-End</td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowOdd\"><td style=\"background-image: url(tbl_bck0350.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\"\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:outer-start-end.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:outer-start-end.code\">code</a><a name=\"Observation.component:outer-start-end.code\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"><span class=\"xhtPieceDeEmphasized\">1</span><span class=\"xhtPieceDeEmphasized\">..</span><span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\" class=\"xhtPieceDeEmphasized\">CodeableConcept</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">81301-4<br/><span class=\"xhtPieceBold\">Required Pattern: </span><div><pre class=\"json\"><code>{\n  \"coding\" : [\n    {\n      \"system\" : \"http://loinc.org\",\n      \"code\" : <span title=\"Structural variant outer start and end\">\"81301-4\"</span>\n    }\n  ]\n}</code></pre></div></td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowEven\"><td style=\"background-image: url(tbl_bck0340.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\"\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:outer-start-end.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:outer-start-end.value[x]\">value[x]</a><a name=\"Observation.component:outer-start-end.value_x_\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"><span class=\"xhtPieceDeEmphasized\">0</span><span class=\"xhtPieceDeEmphasized\">..</span><span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#Range\">Range</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">Imprecise variant outer-bounding range</td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowOdd\"><td style=\"background-image: url(tbl_bck035.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\"\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:coordinate-system\" title=\"Slice coordinate-system: These are different ways of identifying nucleotides or amino acids within a sequence. In the 1-based system, the first unit of the polymer (e.g. the first nucleotide) is counted as number 1. In the 0-based system, the number 0 designates the location before the first nucleotide. Different databases and file types may use different systems.\">component:coordinate-system</a><a name=\"Observation.component:coordinate-system\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\">0..1</td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\" class=\"xhtPieceDeEmphasized\">BackboneElement</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">Coordinate System</td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowEven\"><td style=\"background-image: url(tbl_bck0350.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\"\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:coordinate-system.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:coordinate-system.code\">code</a><a name=\"Observation.component:coordinate-system.code\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"><span class=\"xhtPieceDeEmphasized\">1</span><span class=\"xhtPieceDeEmphasized\">..</span><span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\" class=\"xhtPieceDeEmphasized\">CodeableConcept</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">92822-6<br/><span class=\"xhtPieceBold\">Required Pattern: </span><div><pre class=\"json\"><code>{\n  \"coding\" : [\n    {\n      \"system\" : \"http://loinc.org\",\n      \"code\" : <span title=\"Genomic coordinate system [Type]\">\"92822-6\"</span>\n    }\n  ]\n}</code></pre></div></td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowOdd\"><td style=\"background-image: url(tbl_bck0340.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\"\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:coordinate-system.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:coordinate-system.value[x]\">value[x]</a><a name=\"Observation.component:coordinate-system.value_x_\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\">1..<span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">0-based interval counting | 0-based character counting | 1-based character counting<br class=\"binding\"/><span class=\"xhtPieceBold binding\">Binding: </span><a href=\"https://loinc.org/LL5323-2/\" class=\"binding\">LOINC Answer List LL5323-2</a><span class=\"binding\"> (</span><a href=\"http://hl7.org/fhir/R4/terminologies.html#extensible\" title=\"To be conformant, the concept in this element SHALL be from the specified value set if any of the codes within the value set can apply to the concept being communicated.  If the value set does not cover the concept (based on human review), alternate codings (or, data type allowing, text) may be included instead.\" class=\"binding\">extensible</a><span class=\"binding\">)</span></td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowEven\"><td style=\"background-image: url(tbl_bck035.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\"\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:ref-allele\" title=\"Slice ref-allele: Reference values ('normal') examined within the Reference Sequence.\">component:ref-allele</a><a name=\"Observation.component:ref-allele\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\">0..1</td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\" class=\"xhtPieceDeEmphasized\">BackboneElement</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">Genomic Ref Allele</td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowOdd\"><td style=\"background-image: url(tbl_bck0350.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\"\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:ref-allele.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:ref-allele.code\">code</a><a name=\"Observation.component:ref-allele.code\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"><span class=\"xhtPieceDeEmphasized\">1</span><span class=\"xhtPieceDeEmphasized\">..</span><span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\" class=\"xhtPieceDeEmphasized\">CodeableConcept</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">69547-8<br/><span class=\"xhtPieceBold\">Required Pattern: </span><div><pre class=\"json\"><code>{\n  \"coding\" : [\n    {\n      \"system\" : \"http://loinc.org\",\n      \"code\" : <span title=\"Genomic ref allele [ID]\">\"69547-8\"</span>\n    }\n  ]\n}</code></pre></div></td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowEven\"><td style=\"background-image: url(tbl_bck0340.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\"\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:ref-allele.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:ref-allele.value[x]\">value[x]</a><a name=\"Observation.component:ref-allele.value_x_\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"><span class=\"xhtPieceDeEmphasized\">0</span><span class=\"xhtPieceDeEmphasized\">..</span><span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#string\">string</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">Normalized string per the VCF format.</td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowOdd\"><td style=\"background-image: url(tbl_bck035.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\"\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:alt-allele\" title=\"Slice alt-allele: The genomic alternate allele is the contiguous segment of DNA in the test sample that differs from the reference allele at the same location and thus defines a variant.\">component:alt-allele</a><a name=\"Observation.component:alt-allele\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\">0..1</td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\" class=\"xhtPieceDeEmphasized\">BackboneElement</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">Genomic Alt Allele</td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowEven\"><td style=\"background-image: url(tbl_bck0350.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\"\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:alt-allele.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:alt-allele.code\">code</a><a name=\"Observation.component:alt-allele.code\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"><span class=\"xhtPieceDeEmphasized\">1</span><span class=\"xhtPieceDeEmphasized\">..</span><span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\" class=\"xhtPieceDeEmphasized\">CodeableConcept</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">69551-0<br/><span class=\"xhtPieceBold\">Required Pattern: </span><div><pre class=\"json\"><code>{\n  \"coding\" : [\n    {\n      \"system\" : \"http://loinc.org\",\n      \"code\" : <span title=\"Genomic alt allele [ID]\">\"69551-0\"</span>\n    }\n  ]\n}</code></pre></div></td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowOdd\"><td style=\"background-image: url(tbl_bck0340.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\"\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:alt-allele.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:alt-allele.value[x]\">value[x]</a><a name=\"Observation.component:alt-allele.value_x_\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"><span class=\"xhtPieceDeEmphasized\">0</span><span class=\"xhtPieceDeEmphasized\">..</span><span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#string\">string</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">Normalized string per the VCF format.</td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowEven\"><td style=\"background-image: url(tbl_bck035.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\"\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:coding-change-type\" title=\"Slice coding-change-type: Type of DNA change observed. Convenience property for variants with exact breakpoints, required otherwise.\">component:coding-change-type</a><a name=\"Observation.component:coding-change-type\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\">0..1</td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\" class=\"xhtPieceDeEmphasized\">BackboneElement</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">Coding DNA Change Type</td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowOdd\"><td style=\"background-image: url(tbl_bck0350.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\"\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:coding-change-type.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:coding-change-type.code\">code</a><a name=\"Observation.component:coding-change-type.code\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"><span class=\"xhtPieceDeEmphasized\">1</span><span class=\"xhtPieceDeEmphasized\">..</span><span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\" class=\"xhtPieceDeEmphasized\">CodeableConcept</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">48019-4<br/><span class=\"xhtPieceBold\">Required Pattern: </span><div><pre class=\"json\"><code>{\n  \"coding\" : [\n    {\n      \"system\" : \"http://loinc.org\",\n      \"code\" : <span title=\"DNA change type\">\"48019-4\"</span>\n    }\n  ]\n}</code></pre></div></td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowEven\"><td style=\"background-image: url(tbl_bck0340.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\"\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:coding-change-type.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:coding-change-type.value[x]\">value[x]</a><a name=\"Observation.component:coding-change-type.value_x_\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\">1..<span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">deletion | insertion | delins | SNV | copy_number_gain | copy_number_loss | ... (many)<br class=\"binding\"/><span class=\"xhtPieceBold binding\">Binding: </span><a href=\"ValueSet-dna-change-type-vs.html\" title=\"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs\" class=\"binding\">DNA Change Type</a><span class=\"binding\"> (</span><a href=\"http://hl7.org/fhir/R4/terminologies.html#extensible\" title=\"To be conformant, the concept in this element SHALL be from the specified value set if any of the codes within the value set can apply to the concept being communicated.  If the value set does not cover the concept (based on human review), alternate codings (or, data type allowing, text) may be included instead.\" class=\"binding\">extensible</a><span class=\"binding\">)</span><span class=\"binding\">: </span><span class=\"binding\">Concepts in sequence ontology under SO:0002072</span></td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowOdd\"><td style=\"background-image: url(tbl_bck035.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\"\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:genomic-source-class\" title=\"Slice genomic-source-class: The genomic class of the specimen being analyzed: Germline for inherited genome, somatic for cancer genome, and prenatal for fetal genome.\">component:genomic-source-class</a><a name=\"Observation.component:genomic-source-class\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\">0..1</td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\" class=\"xhtPieceDeEmphasized\">BackboneElement</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">Genomic Source Class</td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowEven\"><td style=\"background-image: url(tbl_bck0350.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\"\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:genomic-source-class.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:genomic-source-class.code\">code</a><a name=\"Observation.component:genomic-source-class.code\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"><span class=\"xhtPieceDeEmphasized\">1</span><span class=\"xhtPieceDeEmphasized\">..</span><span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\" class=\"xhtPieceDeEmphasized\">CodeableConcept</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">48002-0<br/><span class=\"xhtPieceBold\">Required Pattern: </span><div><pre class=\"json\"><code>{\n  \"coding\" : [\n    {\n      \"system\" : \"http://loinc.org\",\n      \"code\" : <span title=\"Genomic source class [Type]\">\"48002-0\"</span>\n    }\n  ]\n}</code></pre></div></td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowOdd\"><td style=\"background-image: url(tbl_bck0340.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\"\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:genomic-source-class.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:genomic-source-class.value[x]\">value[x]</a><a name=\"Observation.component:genomic-source-class.value_x_\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\">1..<span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">Germline | Somatic | Fetal | Likely germline | Likely somatic | Likely fetal | Unknown genomic origin | De novo<br class=\"binding\"/><span class=\"xhtPieceBold binding\">Binding: </span><a href=\"https://loinc.org/LL378-1/\" class=\"binding\">LOINC Answer List LL378-1</a><span class=\"binding\"> (</span><a href=\"http://hl7.org/fhir/R4/terminologies.html#extensible\" title=\"To be conformant, the concept in this element SHALL be from the specified value set if any of the codes within the value set can apply to the concept being communicated.  If the value set does not cover the concept (based on human review), alternate codings (or, data type allowing, text) may be included instead.\" class=\"binding\">extensible</a><span class=\"binding\">)</span></td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowEven\"><td style=\"background-image: url(tbl_bck035.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\"\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:sample-allelic-frequency\" title=\"Slice sample-allelic-frequency: The relative frequency of the allele at a given locus in the sample.\">component:sample-allelic-frequency</a><a name=\"Observation.component:sample-allelic-frequency\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\">0..1</td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\" class=\"xhtPieceDeEmphasized\">BackboneElement</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">Sample Allelic Frequency</td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowOdd\"><td style=\"background-image: url(tbl_bck0350.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\"\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:sample-allelic-frequency.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:sample-allelic-frequency.code\">code</a><a name=\"Observation.component:sample-allelic-frequency.code\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"><span class=\"xhtPieceDeEmphasized\">1</span><span class=\"xhtPieceDeEmphasized\">..</span><span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\" class=\"xhtPieceDeEmphasized\">CodeableConcept</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">81258-6<br/><span class=\"xhtPieceBold\">Required Pattern: </span><div><pre class=\"json\"><code>{\n  \"coding\" : [\n    {\n      \"system\" : \"http://loinc.org\",\n      \"code\" : <span title=\"Sample variant allelic frequency [NFr]\">\"81258-6\"</span>\n    }\n  ]\n}</code></pre></div></td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowEven\"><td style=\"background-image: url(tbl_bck0341.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\"\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:sample-allelic-frequency.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:sample-allelic-frequency.value[x]\">value[x]</a><a name=\"Observation.component:sample-allelic-frequency.value_x_\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"><span class=\"xhtPieceDeEmphasized\">0</span><span class=\"xhtPieceDeEmphasized\">..</span><span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#Quantity\">Quantity</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">Relative frequency in the sample</td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowOdd\"><td style=\"background-image: url(tbl_bck03400.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\"\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:sample-allelic-frequency.value[x].</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:sample-allelic-frequency.value[x].system\">system</a><a name=\"Observation.component:sample-allelic-frequency.value_x_.system\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"><span class=\"xhtPieceDeEmphasized\">0</span><span class=\"xhtPieceDeEmphasized\">..</span><span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#uri\" class=\"xhtPieceDeEmphasized\">uri</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><span class=\"xhtPieceDeEmphasized\">System that defines coded unit form</span><br/><span class=\"xhtPieceBold\">Required Pattern: </span><span class=\"xhtPieceDarkGreen\">http://unitsofmeasure.org</span> (extensions allowed)</td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowEven\"><td style=\"background-image: url(tbl_bck035.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\"\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:allelic-read-depth\" title=\"Slice allelic-read-depth: Specifies the number of reads that identified the allele in question whether it consists of one or a small sequence of contiguous nucleotides. Different methods and purposes require different numbers of reads to be acceptable. Often >400, sometimes as few as 2-4.\">component:allelic-read-depth</a><a name=\"Observation.component:allelic-read-depth\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\">0..1</td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\" class=\"xhtPieceDeEmphasized\">BackboneElement</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">Allelic Read Depth</td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowOdd\"><td style=\"background-image: url(tbl_bck0350.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\"\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:allelic-read-depth.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:allelic-read-depth.code\">code</a><a name=\"Observation.component:allelic-read-depth.code\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"><span class=\"xhtPieceDeEmphasized\">1</span><span class=\"xhtPieceDeEmphasized\">..</span><span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\" class=\"xhtPieceDeEmphasized\">CodeableConcept</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">82121-5<br/><span class=\"xhtPieceBold\">Required Pattern: </span><div><pre class=\"json\"><code>{\n  \"coding\" : [\n    {\n      \"system\" : \"http://loinc.org\",\n      \"code\" : <span title=\"Allelic read depth\">\"82121-5\"</span>\n    }\n  ]\n}</code></pre></div></td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowEven\"><td style=\"background-image: url(tbl_bck0340.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\"\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:allelic-read-depth.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:allelic-read-depth.value[x]\">value[x]</a><a name=\"Observation.component:allelic-read-depth.value_x_\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"><span class=\"xhtPieceDeEmphasized\">0</span><span class=\"xhtPieceDeEmphasized\">..</span><span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#Quantity\">Quantity</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">Unfiltered count of supporting reads</td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowOdd\"><td style=\"background-image: url(tbl_bck035.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\"\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:allelic-state\" title=\"Slice allelic-state: The observed level of occurrence of the variant in the set of chromosomes.\">component:allelic-state</a><a name=\"Observation.component:allelic-state\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\">0..1</td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\" class=\"xhtPieceDeEmphasized\">BackboneElement</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">Allelic State</td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowEven\"><td style=\"background-image: url(tbl_bck0350.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\"\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:allelic-state.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:allelic-state.code\">code</a><a name=\"Observation.component:allelic-state.code\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"><span class=\"xhtPieceDeEmphasized\">1</span><span class=\"xhtPieceDeEmphasized\">..</span><span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\" class=\"xhtPieceDeEmphasized\">CodeableConcept</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">53034-5<br/><span class=\"xhtPieceBold\">Required Pattern: </span><div><pre class=\"json\"><code>{\n  \"coding\" : [\n    {\n      \"system\" : \"http://loinc.org\",\n      \"code\" : <span title=\"Allelic state\">\"53034-5\"</span>\n    }\n  ]\n}</code></pre></div></td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowOdd\"><td style=\"background-image: url(tbl_bck0340.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\"\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:allelic-state.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:allelic-state.value[x]\">value[x]</a><a name=\"Observation.component:allelic-state.value_x_\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\">1..<span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">Heteroplasmic | Homoplasmic | Homozygous | Heterozygous | Hemizygous<br class=\"binding\"/><span class=\"xhtPieceBold binding\">Binding: </span><a href=\"https://loinc.org/LL381-5/\" class=\"binding\">LOINC Answer List LL381-5</a><span class=\"binding\"> (</span><a href=\"http://hl7.org/fhir/R4/terminologies.html#extensible\" title=\"To be conformant, the concept in this element SHALL be from the specified value set if any of the codes within the value set can apply to the concept being communicated.  If the value set does not cover the concept (based on human review), alternate codings (or, data type allowing, text) may be included instead.\" class=\"binding\">extensible</a><span class=\"binding\">)</span></td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowEven\"><td style=\"background-image: url(tbl_bck035.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\"\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:variant-inheritance\" title=\"Slice variant-inheritance: The source or inheritance of a specific germline variation found in an individual patient.\">component:variant-inheritance</a><a name=\"Observation.component:variant-inheritance\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\">0..1</td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\" class=\"xhtPieceDeEmphasized\">BackboneElement</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">Origin of germline genetic variant</td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowOdd\"><td style=\"background-image: url(tbl_bck0350.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\"\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:variant-inheritance.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:variant-inheritance.code\">code</a><a name=\"Observation.component:variant-inheritance.code\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"><span class=\"xhtPieceDeEmphasized\">1</span><span class=\"xhtPieceDeEmphasized\">..</span><span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\" class=\"xhtPieceDeEmphasized\">CodeableConcept</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">94186-4<br/><span class=\"xhtPieceBold\">Required Pattern: </span><div><pre class=\"json\"><code>{\n  \"coding\" : [\n    {\n      \"system\" : \"http://loinc.org\",\n      \"code\" : <span title=\"Origin of germline genetic variant [Type]\">\"94186-4\"</span>\n    }\n  ]\n}</code></pre></div></td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowEven\"><td style=\"background-image: url(tbl_bck0340.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\"\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:variant-inheritance.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:variant-inheritance.value[x]\">value[x]</a><a name=\"Observation.component:variant-inheritance.value_x_\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\">1..<span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">Maternal | Paternal | Unknown<br class=\"binding\"/><span class=\"xhtPieceBold binding\">Binding: </span><a href=\"https://loinc.org/LL5489-1/\" class=\"binding\">LOINC Answer List LL5489-1</a><span class=\"binding\"> (</span><a href=\"http://hl7.org/fhir/R4/terminologies.html#extensible\" title=\"To be conformant, the concept in this element SHALL be from the specified value set if any of the codes within the value set can apply to the concept being communicated.  If the value set does not cover the concept (based on human review), alternate codings (or, data type allowing, text) may be included instead.\" class=\"binding\">extensible</a><span class=\"binding\">)</span></td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowOdd\"><td style=\"background-image: url(tbl_bck035.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\"\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:variant-inheritance-basis\" title=\"Slice variant-inheritance-basis: The method by which the variant inheritance is determined.\">component:variant-inheritance-basis</a><a name=\"Observation.component:variant-inheritance-basis\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\">0..1</td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\" class=\"xhtPieceDeEmphasized\">BackboneElement</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">Evidential basis for variant inheritance</td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowEven\"><td style=\"background-image: url(tbl_bck0350.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\"\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:variant-inheritance-basis.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:variant-inheritance-basis.code\">code</a><a name=\"Observation.component:variant-inheritance-basis.code\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"><span class=\"xhtPieceDeEmphasized\">1</span><span class=\"xhtPieceDeEmphasized\">..</span><span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\" class=\"xhtPieceDeEmphasized\">CodeableConcept</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">Basis for allelic phase<br/><span class=\"xhtPieceBold\">Required Pattern: </span><div><pre class=\"json\"><code>{\n  \"coding\" : [\n    {\n      \"system\" : \"http://loinc.org\",\n      \"code\" : <span title=\"Basis for allelic phase [Type]\">\"82309-6\"</span>\n    }\n  ]\n}</code></pre></div></td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowOdd\"><td style=\"background-image: url(tbl_bck0340.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\"\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:variant-inheritance-basis.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:variant-inheritance-basis.value[x]\">value[x]</a><a name=\"Observation.component:variant-inheritance-basis.value_x_\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\">1..<span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">Directly measured | Family DNA | Family history | Inferred from population data<br class=\"binding\"/><span class=\"xhtPieceBold binding\">Binding: </span><a href=\"https://loinc.org/LL4050-2/\" class=\"binding\">LOINC Answer List LL4050-2</a><span class=\"binding\"> (</span><a href=\"http://hl7.org/fhir/R4/terminologies.html#extensible\" title=\"To be conformant, the concept in this element SHALL be from the specified value set if any of the codes within the value set can apply to the concept being communicated.  If the value set does not cover the concept (based on human review), alternate codings (or, data type allowing, text) may be included instead.\" class=\"binding\">extensible</a><span class=\"binding\">)</span></td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowEven\"><td style=\"background-image: url(tbl_bck035.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\"\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:variation-code\" title=\"Slice variation-code: Accession number in a variant database such as ClinVar, given for cross-reference.\">component:variation-code</a><a name=\"Observation.component:variation-code\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\">0..*</td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\" class=\"xhtPieceDeEmphasized\">BackboneElement</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">Variation Code<br/></td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowOdd\"><td style=\"background-image: url(tbl_bck0350.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\"\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:variation-code.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:variation-code.code\">code</a><a name=\"Observation.component:variation-code.code\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"><span class=\"xhtPieceDeEmphasized\">1</span><span class=\"xhtPieceDeEmphasized\">..</span><span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\" class=\"xhtPieceDeEmphasized\">CodeableConcept</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">81252-9<br/><span class=\"xhtPieceBold\">Required Pattern: </span><div><pre class=\"json\"><code>{\n  \"coding\" : [\n    {\n      \"system\" : \"http://loinc.org\",\n      \"code\" : <span title=\"Discrete genetic variant\">\"81252-9\"</span>\n    }\n  ]\n}</code></pre></div></td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowEven\"><td style=\"background-image: url(tbl_bck0340.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\"\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:variation-code.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:variation-code.value[x]\">value[x]</a><a name=\"Observation.component:variation-code.value_x_\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\">1..<span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">ClinVar ID or similar<br class=\"binding\"/><span class=\"xhtPieceBold binding\">Binding Description: </span><span class=\"binding\"> (</span><a href=\"http://hl7.org/fhir/R4/terminologies.html#example\" title=\"Instances are not expected or even encouraged to draw from the specified value set.  The value set merely provides examples of the types of concepts intended to be included.\" class=\"binding\">example</a><span class=\"binding\">)</span><span class=\"binding\">: </span><span class=\"binding\">Multiple bindings acceptable</span></td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowOdd\"><td style=\"background-image: url(tbl_bck035.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\"\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:representative-protein-hgvs\" title=\"Slice representative-protein-hgvs: Description of the protein (amino acid) sequence change using a valid HGVS-formatted string. The description of the variant is surrounded in parentheses if it is calculated rather than directly observed.\">component:representative-protein-hgvs</a><a name=\"Observation.component:representative-protein-hgvs\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\">0..1</td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\" class=\"xhtPieceDeEmphasized\">BackboneElement</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">Protein (Amino Acid) Change - pHGVS</td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowEven\"><td style=\"background-image: url(tbl_bck0350.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\"\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:representative-protein-hgvs.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:representative-protein-hgvs.code\">code</a><a name=\"Observation.component:representative-protein-hgvs.code\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"><span class=\"xhtPieceDeEmphasized\">1</span><span class=\"xhtPieceDeEmphasized\">..</span><span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\" class=\"xhtPieceDeEmphasized\">CodeableConcept</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">48005-3<br/><span class=\"xhtPieceBold\">Required Pattern: </span><div><pre class=\"json\"><code>{\n  \"coding\" : [\n    {\n      \"system\" : \"http://loinc.org\",\n      \"code\" : <span title=\"Amino acid change (pHGVS)\">\"48005-3\"</span>\n    }\n  ]\n}</code></pre></div></td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowOdd\"><td style=\"background-image: url(tbl_bck0340.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\"\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:representative-protein-hgvs.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:representative-protein-hgvs.value[x]\">value[x]</a><a name=\"Observation.component:representative-protein-hgvs.value_x_\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\">1..<span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">A valid HGVS-formatted 'p.' string, e.g. NP_000050.2:p.(Asn1836Lys)<br class=\"binding\"/><span class=\"xhtPieceBold binding\">Binding: </span><a href=\"ValueSet-hgvs-vs.html\" title=\"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs\" class=\"binding\">Human Genome Variation Society (HGVS) Nomenclature</a><span class=\"binding\"> (</span><a href=\"http://hl7.org/fhir/R4/terminologies.html#required\" title=\"To be conformant, the concept in this element SHALL be from the specified value set.\" class=\"binding\">required</a><span class=\"binding\">)</span></td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowEven\"><td style=\"background-image: url(tbl_bck035.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\"\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:copy-number\" title=\"Slice copy-number: The copy number of the large variant. In HGVS, this is the numeric value following the “X”. It is a unit-less value. If the value determined by the assay is not a whole number, a range or decimal number can be specified. Note that a copy number of 1 can imply a deletion.\">component:copy-number</a><a name=\"Observation.component:copy-number\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\">0..1</td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\" class=\"xhtPieceDeEmphasized\">BackboneElement</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">Genomic Structural Variant Copy Number</td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowOdd\"><td style=\"background-image: url(tbl_bck0350.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\"\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:copy-number.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:copy-number.code\">code</a><a name=\"Observation.component:copy-number.code\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"><span class=\"xhtPieceDeEmphasized\">1</span><span class=\"xhtPieceDeEmphasized\">..</span><span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\" class=\"xhtPieceDeEmphasized\">CodeableConcept</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">82155-3<br/><span class=\"xhtPieceBold\">Required Pattern: </span><div><pre class=\"json\"><code>{\n  \"coding\" : [\n    {\n      \"system\" : \"http://loinc.org\",\n      \"code\" : <span title=\"Genomic structural variant copy number\">\"82155-3\"</span>\n    }\n  ]\n}</code></pre></div></td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowEven\"><td style=\"background-image: url(tbl_bck0341.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_choice.gif\" alt=\"\" style=\"background-color: white; background-color: inherit\" title=\"Choice of Types\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:copy-number.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:copy-number.value[x]\">value[x]</a><a name=\"Observation.component:copy-number.value_x_\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"><span class=\"xhtPieceDeEmphasized\">0</span><span class=\"xhtPieceDeEmphasized\">..</span><span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"><span class=\"xhtPieceDeEmphasized\">Actual component result</span></td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowOdd\"><td style=\"background-image: url(tbl_bck03410.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\"\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:copy-number.value[x].</span><span title=\"Base StructureDefinition for Quantity Type: A measured amount (or an amount that can potentially be measured). Note that measured amounts include amounts that are not precisely quantified, including amounts involving arbitrary units and floating currencies.\">valueQuantity</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#Quantity\">Quantity</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowEven\"><td style=\"background-image: url(tbl_bck03400.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\"\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:copy-number.value[x].</span><span title=\"Base StructureDefinition for Range Type: A set of ordered Quantities defined by a low and high limit.\">valueRange</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#Range\">Range</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowOdd\"><td style=\"background-image: url(tbl_bck035.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\"\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:variant-confidence-status\" title=\"Slice variant-confidence-status: A code that represents the confidence of a true positive variant call.\">component:variant-confidence-status</a><a name=\"Observation.component:variant-confidence-status\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\">0..1</td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\" class=\"xhtPieceDeEmphasized\">BackboneElement</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">Variant Confidence Status</td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowEven\"><td style=\"background-image: url(tbl_bck0350.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\"\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:variant-confidence-status.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:variant-confidence-status.code\">code</a><a name=\"Observation.component:variant-confidence-status.code\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"><span class=\"xhtPieceDeEmphasized\">1</span><span class=\"xhtPieceDeEmphasized\">..</span><span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\" class=\"xhtPieceDeEmphasized\">CodeableConcept</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">variant-confidence-status<br/><span class=\"xhtPieceBold\">Required Pattern: </span><div><pre class=\"json\"><code>{\n  \"coding\" : [\n    {\n      \"system\" : \"http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs\",\n      \"code\" : <span title=\"Variant Confidence Status\">\"variant-confidence-status\"</span>\n    }\n  ]\n}</code></pre></div></td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowOdd\"><td style=\"background-image: url(tbl_bck0340.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\"\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:variant-confidence-status.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:variant-confidence-status.value[x]\">value[x]</a><a name=\"Observation.component:variant-confidence-status.value_x_\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\">1..<span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">High | Intermediate | Low<br class=\"binding\"/><span class=\"xhtPieceBold binding\">Binding: </span><a href=\"ValueSet-variant-confidence-status-vs.html\" title=\"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/variant-confidence-status-vs\" class=\"binding\">Variant Confidence Status</a><span class=\"binding\"> (</span><a href=\"http://hl7.org/fhir/R4/terminologies.html#required\" title=\"To be conformant, the concept in this element SHALL be from the specified value set.\" class=\"binding\">required</a><span class=\"binding\">)</span></td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowEven\"><td style=\"background-image: url(tbl_bck035.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\"\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:repeat-motif\" title=\"Slice repeat-motif: Nucleotides of a repeat expansion motif.\">component:repeat-motif</a><a name=\"Observation.component:repeat-motif\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\">0..*</td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\" class=\"xhtPieceDeEmphasized\">BackboneElement</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">Repeat Motif<br/></td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowOdd\"><td style=\"background-image: url(tbl_bck0352.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_extension_simple.png\" alt=\"\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Simple Extension\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:repeat-motif.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:repeat-motif.extension\">Slices for extension</a><a name=\"Observation.component:repeat-motif.extension\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"><span class=\"xhtPieceDeEmphasized\">0</span><span class=\"xhtPieceDeEmphasized\">..</span><span class=\"xhtPieceDeEmphasized\">*</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/extensibility.html#Extension\" class=\"xhtPieceDeEmphasized\">Extension</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><span class=\"xhtPieceDeEmphasized\">Extension</span><br/><span class=\"xhtPieceBold\">Slice: </span>Unordered, Open by value:url</td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowEven\"><td style=\"background-image: url(tbl_bck0353.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice.png\" alt=\"\" style=\"background-color: white; background-color: inherit\" title=\"Slice Definition\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:repeat-motif.</span>Slices for extension<a name=\"Observation.component.extension\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\">Content/Rules for all slices</td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowOdd\"><td style=\"background-image: url(tbl_bck03524.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\"\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:repeat-motif.Slices for extension.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:repeat-motif.extension:repeat-motif-order\" title=\"Extension URL = http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/repeat-motif-order\">extension:repeat-motif-order</a><a name=\"Observation.component:repeat-motif.extension:repeat-motif-order\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\">0..1</td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#positiveInt\">positiveInt</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><span class=\"xhtPieceDeEmphasized\">Repeat Motif Order</span><br/><span class=\"xhtPieceBold\">URL: </span><a href=\"StructureDefinition-repeat-motif-order.html\">http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/repeat-motif-order</a></td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowEven\"><td style=\"background-image: url(tbl_bck0350.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\"\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:repeat-motif.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:repeat-motif.code\">code</a><a name=\"Observation.component:repeat-motif.code\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"><span class=\"xhtPieceDeEmphasized\">1</span><span class=\"xhtPieceDeEmphasized\">..</span><span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\" class=\"xhtPieceDeEmphasized\">CodeableConcept</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">repeat-motif<br/><span class=\"xhtPieceBold\">Required Pattern: </span><div><pre class=\"json\"><code>{\n  \"coding\" : [\n    {\n      \"system\" : \"http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs\",\n      \"code\" : <span title=\"Repeat Expansion Motif\">\"repeat-motif\"</span>\n    }\n  ]\n}</code></pre></div></td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowOdd\"><td style=\"background-image: url(tbl_bck0340.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\"\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:repeat-motif.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:repeat-motif.value[x]\">value[x]</a><a name=\"Observation.component:repeat-motif.value_x_\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\">1..<span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#string\">string</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">CAG</td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowEven\"><td style=\"background-image: url(tbl_bck025.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\"\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:repeat-number\" title=\"Slice repeat-number: Number of repeats of a repeat expansion.\">component:repeat-number</a><a name=\"Observation.component:repeat-number\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\">0..*</td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\" class=\"xhtPieceDeEmphasized\">BackboneElement</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">Repeat Number<br/></td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowOdd\"><td style=\"background-image: url(tbl_bck0252.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_extension_simple.png\" alt=\"\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Simple Extension\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:repeat-number.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:repeat-number.extension\">Slices for extension</a><a name=\"Observation.component:repeat-number.extension\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"><span class=\"xhtPieceDeEmphasized\">0</span><span class=\"xhtPieceDeEmphasized\">..</span><span class=\"xhtPieceDeEmphasized\">*</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/extensibility.html#Extension\" class=\"xhtPieceDeEmphasized\">Extension</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><span class=\"xhtPieceDeEmphasized\">Extension</span><br/><span class=\"xhtPieceBold\">Slice: </span>Unordered, Open by value:url</td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowEven\"><td style=\"background-image: url(tbl_bck0253.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice.png\" alt=\"\" style=\"background-color: white; background-color: inherit\" title=\"Slice Definition\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:repeat-number.</span>Slices for extension<a name=\"Observation.component.extension.2\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\">Content/Rules for all slices</td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowOdd\"><td style=\"background-image: url(tbl_bck02524.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slicer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\"\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:repeat-number.Slices for extension.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:repeat-number.extension:repeat-motif-order\" title=\"Extension URL = http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/repeat-motif-order\">extension:repeat-motif-order</a><a name=\"Observation.component:repeat-number.extension:repeat-motif-order\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\">0..1</td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#positiveInt\">positiveInt</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><span class=\"xhtPieceDeEmphasized\">Repeat Motif Order</span><br/><span class=\"xhtPieceBold\">URL: </span><a href=\"StructureDefinition-repeat-motif-order.html\">http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/repeat-motif-order</a></td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowEven\"><td style=\"background-image: url(tbl_bck0250.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\"\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:repeat-number.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:repeat-number.code\">code</a><a name=\"Observation.component:repeat-number.code\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\"><span class=\"xhtPieceDeEmphasized\">1</span><span class=\"xhtPieceDeEmphasized\">..</span><span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\" class=\"xhtPieceDeEmphasized\">CodeableConcept</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">repeat-number<br/><span class=\"xhtPieceBold\">Required Pattern: </span><div><pre class=\"json\"><code>{\n  \"coding\" : [\n    {\n      \"system\" : \"http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs\",\n      \"code\" : <span title=\"Number of Repeat Expansions\">\"repeat-number\"</span>\n    }\n  ]\n}</code></pre></div></td></tr>#xD;\n<tr class=\"xhtRowBorder0 xhtRowOdd\"><td style=\"background-image: url(tbl_bck0240.png)\" class=\"hierarchy xhtCellBorder0 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\"\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">Observation.Slices for component.component:repeat-number.</span><a href=\"StructureDefinition-variant-definitions.html#Observation.component:repeat-number.value[x]\">value[x]</a><a name=\"Observation.component:repeat-number.value_x_\"> </a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"/><td style=\"\" class=\"hierarchy xhtCellBorder0\">1..<span class=\"xhtPieceDeEmphasized\">1</span></td><td style=\"\" class=\"hierarchy xhtCellBorder0\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#Quantity\">Quantity</a></td><td style=\"\" class=\"hierarchy xhtCellBorder0\">40</td></tr>#xD;\n<tr><td colspan=\"5\" class=\"hierarchy\"><br/><a href=\"https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views\" title=\"Legend for this format\"><img src=\"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAABmJLR0QA/wD/AP+gvaeTAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3goXBCwdPqAP0wAAAldJREFUOMuNk0tIlFEYhp9z/vE2jHkhxXA0zJCMitrUQlq4lnSltEqCFhFG2MJFhIvIFpkEWaTQqjaWZRkp0g26URZkTpbaaOJkDqk10szoODP//7XIMUe0elcfnPd9zsfLOYplGrpRwZaqTtw3K7PtGem7Q6FoidbGgqHVy/HRb669R+56zx7eRV1L31JGxYbBtjKK93cxeqfyQHbehkZbUkK20goELEuIzEd+dHS+qz/Y8PTSif0FnGkbiwcAjHaU1+QWOptFiyCLp/LnKptpqIuXHx6rbR26kJcBX3yLgBfnd7CxwJmflpP2wUg0HIAoUUpZBmKzELGWcN8nAr6Gpu7tLU/CkwAaoKTWRSQyt89Q8w6J+oVQkKnBoblH7V0PPvUOvDYXfopE/SJmALsxnVm6LbkotrUtNowMeIrVrBcBpaMmdS0j9df7abpSuy7HWehwJdt1lhVwi/J58U5beXGAF6c3UXLycw1wdFklArBn87xdh0ZsZtArghBdAA3+OEDVubG4UEzP6x1FOWneHh2VDAHBAt80IbdXDcesNoCvs3E5AFyNSU5nbrDPZpcUEQQTFZiEVx+51fxMhhyJEAgvlriadIJZZksRuwBYMOPBbO3hePVVqgEJhFeUuFLhIPkRP6BQLIBrmMenujm/3g4zc398awIe90Zb5A1vREALqneMcYgP/xVQWlG+Ncu5vgwwlaUNx+3799rfe96u9K0JSDXcOzOTJg4B6IgmXfsygc7/Bvg9g9E58/cDVmGIBOP/zT8Bz1zqWqpbXIsd0O9hajXfL6u4BaOS6SeWAAAAAElFTkSuQmCC\" alt=\"doco\" style=\"background-color: inherit\"/> Documentation for this format</a></td></tr></table></div>"
  ] ;
  fhir:DomainResource.extension [
     fhir:index 0 ;
     fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-wg" ] ;
     fhir:Extension.valueCode [ fhir:value "cg" ]
  ], [
     fhir:index 1 ;
     fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm" ] ;
     fhir:Extension.valueInteger [
       fhir:value "2"^^xsd:integer ;
       fhir:Element.extension [
         fhir:index 0 ;
         fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom" ] ;
         fhir:Extension.valueCanonical [
           fhir:value "http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting" ;
           fhir:link <http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting>
         ]
       ]
     ]
  ], [
     fhir:index 2 ;
     fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status" ] ;
     fhir:Extension.valueCode [
       fhir:value "trial-use" ;
       fhir:Element.extension [
         fhir:index 0 ;
         fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom" ] ;
         fhir:Extension.valueCanonical [
           fhir:value "http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting" ;
           fhir:link <http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting>
         ]
       ]
     ]
  ] ;
  fhir:StructureDefinition.url [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/variant"] ;
  fhir:StructureDefinition.version [ fhir:value "4.0.0-cibuild"] ;
  fhir:StructureDefinition.name [ fhir:value "Variant"] ;
  fhir:StructureDefinition.title [ fhir:value "Variant"] ;
  fhir:StructureDefinition.status [ fhir:value "active"] ;
  fhir:StructureDefinition.date [ fhir:value "2026-11-02T21:42:53+00:00"^^xsd:dateTime] ;
  fhir:StructureDefinition.publisher [ fhir:value "HL7 International / Clinical Genomics"] ;
  fhir:StructureDefinition.contact [
     fhir:index 0 ;
     fhir:ContactDetail.name [ fhir:value "HL7 International / Clinical Genomics" ] ;
     fhir:ContactDetail.telecom [
       fhir:index 0 ;
       fhir:ContactPoint.system [ fhir:value "url" ] ;
       fhir:ContactPoint.value [ fhir:value "http://www.hl7.org/Special/committees/clingenomics" ]
     ], [
       fhir:index 1 ;
       fhir:ContactPoint.system [ fhir:value "email" ] ;
       fhir:ContactPoint.value [ fhir:value "cg@lists.HL7.org" ]
     ]
  ] ;
  fhir:StructureDefinition.description [ fhir:value "Details about a set of changes in the tested sample compared to a reference sequence."] ;
  fhir:StructureDefinition.jurisdiction [
     fhir:index 0 ;
     fhir:CodeableConcept.coding [
       fhir:index 0 ;
       fhir:Coding.system [ fhir:value "http://unstats.un.org/unsd/methods/m49/m49.htm" ] ;
       fhir:Coding.code [ fhir:value "001" ] ;
       fhir:Coding.display [ fhir:value "World" ]
     ]
  ] ;
  fhir:StructureDefinition.copyright [ fhir:value "This material contains content from LOINC (http://loinc.org). LOINC is copyright © 1995-2020, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC® is a registered United States trademark of Regenstrief Institute, Inc."] ;
  fhir:StructureDefinition.fhirVersion [ fhir:value "4.0.1"] ;
  fhir:StructureDefinition.mapping [
     fhir:index 0 ;
     fhir:StructureDefinition.mapping.identity [ fhir:value "workflow" ] ;
     fhir:StructureDefinition.mapping.uri [ fhir:value "http://hl7.org/fhir/workflow" ] ;
     fhir:StructureDefinition.mapping.name [ fhir:value "Workflow Pattern" ]
  ], [
     fhir:index 1 ;
     fhir:StructureDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
     fhir:StructureDefinition.mapping.uri [ fhir:value "http://snomed.info/conceptdomain" ] ;
     fhir:StructureDefinition.mapping.name [ fhir:value "SNOMED CT Concept Domain Binding" ]
  ], [
     fhir:index 2 ;
     fhir:StructureDefinition.mapping.identity [ fhir:value "v2" ] ;
     fhir:StructureDefinition.mapping.uri [ fhir:value "http://hl7.org/v2" ] ;
     fhir:StructureDefinition.mapping.name [ fhir:value "HL7 v2 Mapping" ]
  ], [
     fhir:index 3 ;
     fhir:StructureDefinition.mapping.identity [ fhir:value "rim" ] ;
     fhir:StructureDefinition.mapping.uri [ fhir:value "http://hl7.org/v3" ] ;
     fhir:StructureDefinition.mapping.name [ fhir:value "RIM Mapping" ]
  ], [
     fhir:index 4 ;
     fhir:StructureDefinition.mapping.identity [ fhir:value "w5" ] ;
     fhir:StructureDefinition.mapping.uri [ fhir:value "http://hl7.org/fhir/fivews" ] ;
     fhir:StructureDefinition.mapping.name [ fhir:value "FiveWs Pattern Mapping" ]
  ], [
     fhir:index 5 ;
     fhir:StructureDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
     fhir:StructureDefinition.mapping.uri [ fhir:value "http://snomed.org/attributebinding" ] ;
     fhir:StructureDefinition.mapping.name [ fhir:value "SNOMED CT Attribute Binding" ]
  ] ;
  fhir:StructureDefinition.kind [ fhir:value "resource"] ;
  fhir:StructureDefinition.abstract [ fhir:value "false"^^xsd:boolean] ;
  fhir:StructureDefinition.type [ fhir:value "Observation"] ;
  fhir:StructureDefinition.baseDefinition [
     fhir:value "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/finding" ;
     fhir:link <http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/finding>
  ] ;
  fhir:StructureDefinition.derivation [ fhir:value "constraint"] ;
  fhir:StructureDefinition.snapshot [
     fhir:Element.extension [
       fhir:index 0 ;
       fhir:Extension.url [ fhir:value "http://hl7.org/fhir/tools/StructureDefinition/snapshot-base-version" ] ;
       fhir:Extension.valueString [ fhir:value "4.0.0-cibuild" ]
     ] ;
     fhir:StructureDefinition.snapshot.element [
       fhir:index 0 ;
       fhir:Element.id [ fhir:value "Observation" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation" ] ;
       fhir:ElementDefinition.short [ fhir:value "Variant" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Measurements and simple assertions made about a patient, device or other subject." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Used for simple observations such as device measurements, laboratory atomic results, vital signs, height, weight, smoking status, comments, etc.  Other resources are used to provide context for observations such as laboratory reports, etc." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "Vital Signs" ;
         fhir:index 0
       ], [
         fhir:value "Measurement" ;
         fhir:index 1
       ], [
         fhir:value "Results" ;
         fhir:index 2
       ], [
         fhir:value "Tests" ;
         fhir:index 3
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "dom-2" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "If the resource is contained in another resource, it SHALL NOT contain nested Resources" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "contained.contained.empty()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "not(parent::f:contained and f:contained)" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/DomainResource" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/DomainResource>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "dom-3" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "not(exists(for $id in f:contained/*/f:id/@value return $contained[not(parent::*/descendant::f:reference/@value=concat('#', $contained/*/id/@value) or descendant::f:reference[@value='#'])]))" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/DomainResource" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/DomainResource>
         ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "dom-4" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "not(exists(f:contained/*/f:meta/f:versionId)) and not(exists(f:contained/*/f:meta/f:lastUpdated))" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/DomainResource" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/DomainResource>
         ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "dom-5" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "If a resource is contained in another resource, it SHALL NOT have a security label" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "contained.meta.security.empty()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "not(exists(f:contained/*/f:meta/f:security))" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/DomainResource" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/DomainResource>
         ]
       ], [
         fhir:index 4 ;
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bestpractice" ] ;
           fhir:Extension.valueBoolean [ fhir:value "true"^^xsd:boolean ]
         ], [
           fhir:index 1 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bestpractice-explanation" ] ;
           fhir:Extension.valueMarkdown [ fhir:value "When a resource has no narrative, only systems that fully understand the data can display the resource to a human safely. Including a human readable representation in the resource makes for a much more robust eco-system and cheaper handling of resources by intermediary systems. Some ecosystems restrict distribution of resources to only those systems that do fully understand the resources, and as a consequence implementers may believe that the narrative is superfluous. However experience shows that such eco-systems often open up to new participants over time." ]
         ] ;
         fhir:ElementDefinition.constraint.key [ fhir:value "dom-6" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "warning" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "A resource should have narrative for robust management" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "text.`div`.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:text/h:div)" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/DomainResource" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/DomainResource>
         ]
       ], [
         fhir:index 5 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "obs-6" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "dataAbsentReason SHALL only be present if Observation.value[x] is not present" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "dataAbsentReason.empty() or value.empty()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "not(exists(f:dataAbsentReason)) or (not(exists(*[starts-with(local-name(.), 'value')])))" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Observation" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Observation>
         ]
       ], [
         fhir:index 6 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "obs-7" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "If Observation.code is the same as an Observation.component.code then the value element associated with the code SHALL NOT be present" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "value.empty() or component.code.where(coding.intersect(%resource.code.coding).exists()).empty()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "not(f:*[starts-with(local-name(.), 'value')] and (for $coding in f:code/f:coding return f:component/f:code/f:coding[f:code/@value=$coding/f:code/@value] [f:system/@value=$coding/f:system/@value]))" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Observation" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Observation>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "Entity. Role, or Act" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "workflow" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "Event" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity|" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX" ]
       ], [
         fhir:index 4 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "Observation[classCode=OBS, moodCode=EVN]" ]
       ]
     ], [
       fhir:index 1 ;
       fhir:Element.id [ fhir:value "Observation.id" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.id" ] ;
       fhir:ElementDefinition.short [ fhir:value "Logical id of this artifact" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The logical id of the resource, as used in the URL for the resource. Once assigned, this value never changes." ] ;
       fhir:ElementDefinition.comment [ fhir:value "The only time that a resource does not have an id is when it is being submitted to the server using a create operation." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Resource.id" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ] ;
           fhir:Extension.valueUrl [ fhir:value "id" ]
         ] ;
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]
     ], [
       fhir:index 2 ;
       fhir:Element.id [ fhir:value "Observation.meta" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.meta" ] ;
       fhir:ElementDefinition.short [ fhir:value "Metadata about the resource" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The metadata about the resource. This is content that is maintained by the infrastructure. Changes to the content might not always be associated with version changes to the resource." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Resource.meta" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Meta" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]
     ], [
       fhir:index 3 ;
       fhir:Element.id [ fhir:value "Observation.implicitRules" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.implicitRules" ] ;
       fhir:ElementDefinition.short [ fhir:value "A set of rules under which this content was created" ] ;
       fhir:ElementDefinition.definition [ fhir:value "A reference to a set of rules that were followed when the resource was constructed, and which must be understood when processing the content. Often, this is a reference to an implementation guide that defines the special rules along with other profiles etc." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Asserting this rule set restricts the content to be only understood by a limited set of trading partners. This inherently limits the usefulness of the data in the long term. However, the existing health eco-system is highly fractured, and not yet ready to define, collect, and exchange data in a generally computable sense. Wherever possible, implementers and/or specification writers should avoid using this element. Often, when used, the URL is a reference to an implementation guide that defines these special rules as part of it's narrative along with other profiles, value sets, etc." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Resource.implicitRules" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "uri" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.isModifierReason [ fhir:value "This element is labeled as a modifier because the implicit rules may provide additional knowledge about the resource that modifies it's meaning or interpretation" ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]
     ], [
       fhir:index 4 ;
       fhir:Element.id [ fhir:value "Observation.language" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.language" ] ;
       fhir:ElementDefinition.short [ fhir:value "Language of the resource content" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The base language in which the resource is written." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Language is provided to support indexing and accessibility (typically, services such as text to speech use the language tag). The html language tag in the narrative applies  to the narrative. The language tag on the resource may be used to specify the language of other presentations generated from the data in the resource. Not all the content has to be in the base language. The Resource.language should not be assumed to apply to the narrative automatically. If a language is specified, it should it also be specified on the div element in the html (see rules in HTML5 for information about the relationship between xml:lang and the html lang attribute)." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Resource.language" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "code" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-maxValueSet" ] ;
           fhir:Extension.valueCanonical [
             fhir:value "http://hl7.org/fhir/ValueSet/all-languages" ;
             fhir:link <http://hl7.org/fhir/ValueSet/all-languages>
           ]
         ], [
           fhir:index 1 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "Language" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "preferred" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "A human language." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/languages|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/languages|4.0.1>
         ]
       ]
     ], [
       fhir:index 5 ;
       fhir:Element.id [ fhir:value "Observation.text" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.text" ] ;
       fhir:ElementDefinition.short [ fhir:value "Text summary of the resource, for human interpretation" ] ;
       fhir:ElementDefinition.definition [ fhir:value "A human-readable narrative that contains a summary of the resource and can be used to represent the content of the resource to a human. The narrative need not encode all the structured data, but is required to contain sufficient detail to make it \"clinically safe\" for a human to just read the narrative. Resource definitions may define what content should be represented in the narrative to ensure clinical safety." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Contained resources do not have narrative. Resources that are not contained SHOULD have a narrative. In some cases, a resource may only have text with little or no additional discrete data (as long as all minOccurs=1 elements are satisfied).  This may be necessary for data from legacy systems where information is captured as a \"text blob\" or where text is additionally entered raw or narrated and encoded information is added later." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "narrative" ;
         fhir:index 0
       ], [
         fhir:value "html" ;
         fhir:index 1
       ], [
         fhir:value "xhtml" ;
         fhir:index 2
       ], [
         fhir:value "display" ;
         fhir:index 3
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "DomainResource.text" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Narrative" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "Act.text?" ]
       ]
     ], [
       fhir:index 6 ;
       fhir:Element.id [ fhir:value "Observation.contained" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.contained" ] ;
       fhir:ElementDefinition.short [ fhir:value "Contained, inline Resources" ] ;
       fhir:ElementDefinition.definition [ fhir:value "These resources do not have an independent existence apart from the resource that contains them - they cannot be identified independently, and nor can they have their own independent transaction scope." ] ;
       fhir:ElementDefinition.comment [ fhir:value "This should never be done when the content can be identified properly, as once identification is lost, it is extremely difficult (and context dependent) to restore it again. Contained resources may have profiles and tags In their meta elements, but SHALL NOT have security labels." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "inline resources" ;
         fhir:index 0
       ], [
         fhir:value "anonymous resources" ;
         fhir:index 1
       ], [
         fhir:value "contained resources" ;
         fhir:index 2
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "DomainResource.contained" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Resource" ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ]
     ], [
       fhir:index 7 ;
       fhir:Element.id [ fhir:value "Observation.extension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.extension" ] ;
       fhir:ElementDefinition.slicing [
         fhir:ElementDefinition.slicing.discriminator [
           fhir:index 0 ;
           fhir:ElementDefinition.slicing.discriminator.type [ fhir:value "value" ] ;
           fhir:ElementDefinition.slicing.discriminator.path [ fhir:value "url" ]
         ] ;
         fhir:ElementDefinition.slicing.ordered [ fhir:value "false"^^xsd:boolean ] ;
         fhir:ElementDefinition.slicing.rules [ fhir:value "open" ]
       ] ;
       fhir:ElementDefinition.short [ fhir:value "Extension" ] ;
       fhir:ElementDefinition.definition [ fhir:value "An Extension" ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "DomainResource.extension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]
     ], [
       fhir:index 8 ;
       fhir:Element.id [ fhir:value "Observation.extension:secondary-finding" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.extension" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "secondary-finding" ] ;
       fhir:ElementDefinition.short [ fhir:value "Secondary findings are genetic test results that provide information about variants in a gene unrelated to the primary purpose for the testing, most often discovered when [Whole Exome Sequencing (WES)](https://en.wikipedia.org/wiki/Exome_sequencing) or [Whole Genome Sequencing (WGS)](https://en.wikipedia.org/wiki/Whole_genome_sequencing) is performed. This extension should be used to denote when a genetic finding is being shared as a secondary finding, and ideally refer to a corresponding guideline or policy statement.\n\nFor more detail, please see:\nhttps://ghr.nlm.nih.gov/primer/testing/secondaryfindings" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Secondary findings are genetic test results that provide information about variants in a gene unrelated to the primary purpose for the testing, most often discovered when [Whole Exome Sequencing (WES)](https://en.wikipedia.org/wiki/Exome_sequencing) or [Whole Genome Sequencing (WGS)](https://en.wikipedia.org/wiki/Whole_genome_sequencing) is performed. This extension should be used to denote when a genetic finding is being shared as a secondary finding, and ideally refer to a corresponding guideline or policy statement.\n\nFor more detail, please see:\nhttps://ghr.nlm.nih.gov/primer/testing/secondaryfindings." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "DomainResource.extension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ;
         fhir:ElementDefinition.type.profile [
           fhir:value "http://hl7.org/fhir/StructureDefinition/observation-secondaryFinding|5.4.0" ;
           fhir:index 0 ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/observation-secondaryFinding|5.4.0>
         ]
       ] ;
       fhir:ElementDefinition.condition [
         fhir:value "ele-1" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]
     ], [
       fhir:index 9 ;
       fhir:Element.id [ fhir:value "Observation.extension:body-structure" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.extension" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "body-structure" ] ;
       fhir:ElementDefinition.short [ fhir:value "Target anatomic location or structure" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Record details about the anatomical location of a specimen or body part. This resource may be used when a coded concept does not provide the necessary detail needed for the use case." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "DomainResource.extension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ;
         fhir:ElementDefinition.type.profile [
           fhir:value "http://hl7.org/fhir/StructureDefinition/bodySite|5.4.0" ;
           fhir:index 0 ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/bodySite|5.4.0>
         ]
       ] ;
       fhir:ElementDefinition.condition [
         fhir:value "ele-1" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]
     ], [
       fhir:index 10 ;
       fhir:Element.id [ fhir:value "Observation.modifierExtension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.modifierExtension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the resource and that modifies the understanding of the element that contains it and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension)." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "DomainResource.modifierExtension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the resource that contains them" ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ]
     ], [
       fhir:index 11 ;
       fhir:Element.id [ fhir:value "Observation.identifier" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.identifier" ] ;
       fhir:ElementDefinition.short [ fhir:value "Business Identifier for observation" ] ;
       fhir:ElementDefinition.definition [ fhir:value "A unique identifier assigned to this observation." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Allows observations to be distinguished and referenced." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.identifier" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Identifier" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "workflow" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "Event.identifier" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.identifier" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.21  For OBX segments from systems without OBX-21 support a combination of ORC/OBR and OBX must be negotiated between trading partners to uniquely identify the OBX segment. Depending on how V2 has been implemented each of these may be an option: 1) OBR-3 + OBX-3 + OBX-4 or 2) OBR-3 + OBR-4 + OBX-3 + OBX-4 or 2) some other way to uniquely ID the OBR/ORC + OBX-3 + OBX-4." ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "id" ]
       ]
     ], [
       fhir:index 12 ;
       fhir:Element.id [ fhir:value "Observation.basedOn" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.basedOn" ] ;
       fhir:ElementDefinition.short [ fhir:value "Fulfills plan, proposal or order" ] ;
       fhir:ElementDefinition.definition [ fhir:value "A plan, proposal or order that is fulfilled in whole or in part by this event.  For example, a MedicationRequest may require a patient to have laboratory test performed before  it is dispensed." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Allows tracing of authorization for the event and tracking whether proposals/recommendations were acted upon." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "Fulfills" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.basedOn" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Reference" ] ;
         fhir:ElementDefinition.type.targetProfile [
           fhir:value "http://hl7.org/fhir/StructureDefinition/CarePlan|4.0.1" ;
           fhir:index 0 ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/CarePlan|4.0.1>
         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/DeviceRequest|4.0.1" ;
           fhir:index 1 ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/DeviceRequest|4.0.1>
         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/ImmunizationRecommendation|4.0.1" ;
           fhir:index 2 ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/ImmunizationRecommendation|4.0.1>
         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/MedicationRequest|4.0.1" ;
           fhir:index 3 ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/MedicationRequest|4.0.1>
         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/NutritionOrder|4.0.1" ;
           fhir:index 4 ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/NutritionOrder|4.0.1>
         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/ServiceRequest|4.0.1" ;
           fhir:index 5 ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/ServiceRequest|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "workflow" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "Event.basedOn" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "ORC" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value ".inboundRelationship[typeCode=COMP].source[moodCode=EVN]" ]
       ]
     ], [
       fhir:index 13 ;
       fhir:Element.id [ fhir:value "Observation.partOf" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.partOf" ] ;
       fhir:ElementDefinition.short [ fhir:value "Part of referenced event" ] ;
       fhir:ElementDefinition.definition [ fhir:value "A larger event of which this particular Observation is a component or step.  For example,  an observation as part of a procedure." ] ;
       fhir:ElementDefinition.comment [ fhir:value "To link an Observation to an Encounter use `encounter`.  See the  [Notes](http://hl7.org/fhir/R4/observation.html#obsgrouping) below for guidance on referencing another Observation." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "Container" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.partOf" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Reference" ] ;
         fhir:ElementDefinition.type.targetProfile [
           fhir:value "http://hl7.org/fhir/StructureDefinition/MedicationAdministration" ;
           fhir:index 0 ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/MedicationAdministration>
         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/MedicationDispense" ;
           fhir:index 1 ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/MedicationDispense>
         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/MedicationStatement" ;
           fhir:index 2 ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/MedicationStatement>
         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Procedure" ;
           fhir:index 3 ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Procedure>
         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Immunization" ;
           fhir:index 4 ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Immunization>
         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/ImagingStudy" ;
           fhir:index 5 ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/ImagingStudy>
         ], [
           fhir:value "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/genomic-study" ;
           fhir:index 6 ;
           fhir:link <http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/genomic-study>
         ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "workflow" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "Event.partOf" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "Varies by domain" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value ".outboundRelationship[typeCode=FLFS].target" ]
       ]
     ], [
       fhir:index 14 ;
       fhir:Element.id [ fhir:value "Observation.status" ] ;
       fhir:Element.extension [
         fhir:index 0 ;
         fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-display-hint" ] ;
         fhir:Extension.valueString [ fhir:value "default: final" ]
       ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.status" ] ;
       fhir:ElementDefinition.short [ fhir:value "registered | preliminary | final | amended +" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The status of the result value." ] ;
       fhir:ElementDefinition.comment [ fhir:value "This element is labeled as a modifier because the status contains codes that mark the resource as not currently valid." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Need to track the status of individual results. Some results are finalized before the whole report is finalized." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.status" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "code" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.isModifierReason [ fhir:value "This element is labeled as a modifier because it is a status element that contains status entered-in-error which means that the resource should not be treated as valid" ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationStatus" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "required" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes providing the status of an observation." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-status|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-status|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "workflow" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "Event.status" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.status" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 445584004 |Report by finality status|" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-11" ]
       ], [
         fhir:index 4 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "status  Amended & Final are differentiated by whether it is the subject of a ControlAct event with a type of \"revise\"" ]
       ]
     ], [
       fhir:index 15 ;
       fhir:Element.id [ fhir:value "Observation.category" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.category" ] ;
       fhir:ElementDefinition.slicing [
         fhir:ElementDefinition.slicing.discriminator [
           fhir:index 0 ;
           fhir:ElementDefinition.slicing.discriminator.type [ fhir:value "value" ] ;
           fhir:ElementDefinition.slicing.discriminator.path [ fhir:value "coding" ]
         ] ;
         fhir:ElementDefinition.slicing.description [ fhir:value "Slice based on the category.code pattern" ] ;
         fhir:ElementDefinition.slicing.ordered [ fhir:value "false"^^xsd:boolean ] ;
         fhir:ElementDefinition.slicing.rules [ fhir:value "open" ]
       ] ;
       fhir:ElementDefinition.short [ fhir:value "Classification of  type of observation" ] ;
       fhir:ElementDefinition.definition [ fhir:value "A code that classifies the general type of observation being made." ] ;
       fhir:ElementDefinition.comment [ fhir:value "In addition to the required category valueset, this element allows various categorization schemes based on the owner’s definition of the category and effectively multiple categories can be used at once.  The level of granularity is defined by the category concepts in the value set." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Used for filtering what observations are retrieved and displayed." ] ;
       fhir:ElementDefinition.min [ fhir:value "2"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.category" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationCategory" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "preferred" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes for high level observation categories." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-category|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-category|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.class" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value ".outboundRelationship[typeCode=\"COMP].target[classCode=\"LIST\", moodCode=\"EVN\"].code" ]
       ]
     ], [
       fhir:index 16 ;
       fhir:Element.id [ fhir:value "Observation.category:labCategory" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.category" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "labCategory" ] ;
       fhir:ElementDefinition.short [ fhir:value "Classification of  type of observation" ] ;
       fhir:ElementDefinition.definition [ fhir:value "A code that classifies the general type of observation being made." ] ;
       fhir:ElementDefinition.comment [ fhir:value "In addition to the required category valueset, this element allows various categorization schemes based on the owner’s definition of the category and effectively multiple categories can be used at once.  The level of granularity is defined by the category concepts in the value set." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Used for filtering what observations are retrieved and displayed." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.category" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationCategory" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "preferred" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes for high level observation categories." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-category|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-category|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.class" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value ".outboundRelationship[typeCode=\"COMP].target[classCode=\"LIST\", moodCode=\"EVN\"].code" ]
       ]
     ], [
       fhir:index 17 ;
       fhir:Element.id [ fhir:value "Observation.category:labCategory.id" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.category.id" ] ;
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ] ;
           fhir:Extension.valueUrl [ fhir:value "string" ]
         ] ;
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 18 ;
       fhir:Element.id [ fhir:value "Observation.category:labCategory.extension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.category.extension" ] ;
       fhir:ElementDefinition.slicing [
         fhir:ElementDefinition.slicing.discriminator [
           fhir:index 0 ;
           fhir:ElementDefinition.slicing.discriminator.type [ fhir:value "value" ] ;
           fhir:ElementDefinition.slicing.discriminator.path [ fhir:value "url" ]
         ] ;
         fhir:ElementDefinition.slicing.description [ fhir:value "Extensions are always sliced by (at least) url" ] ;
         fhir:ElementDefinition.slicing.rules [ fhir:value "open" ]
       ] ;
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 19 ;
       fhir:Element.id [ fhir:value "Observation.category:labCategory.coding" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.category.coding" ] ;
       fhir:ElementDefinition.short [ fhir:value "Code defined by a terminology system" ] ;
       fhir:ElementDefinition.definition [ fhir:value "A reference to a code defined by a terminology system." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information.  Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Allows for alternative encodings within a code system, and translations to other code systems." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "CodeableConcept.coding" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Coding" ]
       ] ;
       fhir:ElementDefinition.patternCoding [
         fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/observation-category" ] ;
         fhir:Coding.code [ fhir:value "laboratory" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "C*E.1-8, C*E.10-22" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "union(., ./translation)" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "orim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "fhir:CodeableConcept.coding rdfs:subPropertyOf dt:CD.coding" ]
       ]
     ], [
       fhir:index 20 ;
       fhir:Element.id [ fhir:value "Observation.category:labCategory.text" ] ;
       fhir:Element.extension [
         fhir:index 0 ;
         fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-translatable" ] ;
         fhir:Extension.valueBoolean [ fhir:value "true"^^xsd:boolean ]
       ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.category.text" ] ;
       fhir:ElementDefinition.short [ fhir:value "Plain text representation of the concept" ] ;
       fhir:ElementDefinition.definition [ fhir:value "A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Very often the text is the same as a displayName of one of the codings." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "CodeableConcept.text" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "string" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "C*E.9. But note many systems use C*E.2 for this" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "./originalText[mediaType/code=\"text/plain\"]/data" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "orim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "fhir:CodeableConcept.text rdfs:subPropertyOf dt:CD.originalText" ]
       ]
     ], [
       fhir:index 21 ;
       fhir:Element.id [ fhir:value "Observation.category:geCategory" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.category" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "geCategory" ] ;
       fhir:ElementDefinition.short [ fhir:value "Classification of  type of observation" ] ;
       fhir:ElementDefinition.definition [ fhir:value "A code that classifies the general type of observation being made." ] ;
       fhir:ElementDefinition.comment [ fhir:value "In addition to the required category valueset, this element allows various categorization schemes based on the owner’s definition of the category and effectively multiple categories can be used at once.  The level of granularity is defined by the category concepts in the value set." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Used for filtering what observations are retrieved and displayed." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.category" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationCategory" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "preferred" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes for high level observation categories." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-category|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-category|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.class" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value ".outboundRelationship[typeCode=\"COMP].target[classCode=\"LIST\", moodCode=\"EVN\"].code" ]
       ]
     ], [
       fhir:index 22 ;
       fhir:Element.id [ fhir:value "Observation.category:geCategory.id" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.category.id" ] ;
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ] ;
           fhir:Extension.valueUrl [ fhir:value "string" ]
         ] ;
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 23 ;
       fhir:Element.id [ fhir:value "Observation.category:geCategory.extension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.category.extension" ] ;
       fhir:ElementDefinition.slicing [
         fhir:ElementDefinition.slicing.discriminator [
           fhir:index 0 ;
           fhir:ElementDefinition.slicing.discriminator.type [ fhir:value "value" ] ;
           fhir:ElementDefinition.slicing.discriminator.path [ fhir:value "url" ]
         ] ;
         fhir:ElementDefinition.slicing.description [ fhir:value "Extensions are always sliced by (at least) url" ] ;
         fhir:ElementDefinition.slicing.rules [ fhir:value "open" ]
       ] ;
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 24 ;
       fhir:Element.id [ fhir:value "Observation.category:geCategory.coding" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.category.coding" ] ;
       fhir:ElementDefinition.short [ fhir:value "Code defined by a terminology system" ] ;
       fhir:ElementDefinition.definition [ fhir:value "A reference to a code defined by a terminology system." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information.  Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Allows for alternative encodings within a code system, and translations to other code systems." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "CodeableConcept.coding" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Coding" ]
       ] ;
       fhir:ElementDefinition.patternCoding [
         fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/v2-0074" ] ;
         fhir:Coding.code [ fhir:value "GE" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "C*E.1-8, C*E.10-22" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "union(., ./translation)" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "orim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "fhir:CodeableConcept.coding rdfs:subPropertyOf dt:CD.coding" ]
       ]
     ], [
       fhir:index 25 ;
       fhir:Element.id [ fhir:value "Observation.category:geCategory.text" ] ;
       fhir:Element.extension [
         fhir:index 0 ;
         fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-translatable" ] ;
         fhir:Extension.valueBoolean [ fhir:value "true"^^xsd:boolean ]
       ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.category.text" ] ;
       fhir:ElementDefinition.short [ fhir:value "Plain text representation of the concept" ] ;
       fhir:ElementDefinition.definition [ fhir:value "A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Very often the text is the same as a displayName of one of the codings." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "CodeableConcept.text" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "string" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "C*E.9. But note many systems use C*E.2 for this" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "./originalText[mediaType/code=\"text/plain\"]/data" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "orim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "fhir:CodeableConcept.text rdfs:subPropertyOf dt:CD.originalText" ]
       ]
     ], [
       fhir:index 26 ;
       fhir:Element.id [ fhir:value "Observation.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "69548-6" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"name\"." ] ;
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and, if present, component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "Name" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.code" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           a loinc:69548-6 ;
           fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
           fhir:Coding.code [ fhir:value "69548-6" ]
         ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "workflow" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "Event.code" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR < 386053000 |Evaluation procedure|" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]
       ], [
         fhir:index 4 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]
       ], [
         fhir:index 5 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "116680003 |Is a|" ]
       ]
     ], [
       fhir:index 27 ;
       fhir:Element.id [ fhir:value "Observation.subject" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.subject" ] ;
       fhir:ElementDefinition.short [ fhir:value "Who and/or what the observation is about" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The patient, or group of patients, location, or device this observation is about and into whose record the observation is placed. If the actual focus of the observation is different from the subject (or a sample of, part, or region of the subject), the `focus` element or the `code` itself specifies the actual focus of the observation." ] ;
       fhir:ElementDefinition.comment [ fhir:value "One would expect this element to be a cardinality of 1..1. The only circumstance in which the subject can be missing is when the observation is made by a device that does not know the patient. In this case, the observation SHALL be matched to a patient through some context/channel matching technique, and at this point, the observation should be updated." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Observations have no value if you don't know who or what they're about." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.subject" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Reference" ] ;
         fhir:ElementDefinition.type.targetProfile [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Patient|4.0.1" ;
           fhir:index 0 ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Patient|4.0.1>
         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Group|4.0.1" ;
           fhir:index 1 ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Group|4.0.1>
         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Device|4.0.1" ;
           fhir:index 2 ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Device|4.0.1>
         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Location|4.0.1" ;
           fhir:index 3 ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Location|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "workflow" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "Event.subject" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.subject[x]" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "PID-3" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "participation[typeCode=RTGT]" ]
       ], [
         fhir:index 4 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.subject" ]
       ]
     ], [
       fhir:index 28 ;
       fhir:Element.id [ fhir:value "Observation.focus" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.focus" ] ;
       fhir:ElementDefinition.short [ fhir:value "What the observation is about, when it is not about the subject of record" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The actual focus of an observation when it is not the patient of record representing something or someone associated with the patient such as a spouse, parent, fetus, or donor. For example, fetus observations in a mother's record.  The focus of an observation could also be an existing condition,  an intervention, the subject's diet,  another observation of the subject,  or a body structure such as tumor or implanted device.   An example use case would be using the Observation resource to capture whether the mother is trained to change her child's tracheostomy tube. In this example, the child is the patient of record and the mother is the focus." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Typically, an observation is made about the subject - a patient, or group of patients, location, or device - and the distinction between the subject and what is directly measured for an observation is specified in the observation code itself ( e.g., \"Blood Glucose\") and does not need to be represented separately using this element.  Use `specimen` if a reference to a specimen is required.  If a code is required instead of a resource use either  `bodysite` for bodysites or the standard extension [focusCode](http://hl7.org/fhir/R4/extension-observation-focuscode.html)." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.focus" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Reference" ] ;
         fhir:ElementDefinition.type.targetProfile [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Resource|4.0.1" ;
           fhir:index 0 ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Resource|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.subject[x]" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "participation[typeCode=SBJ]" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.subject" ]
       ]
     ], [
       fhir:index 29 ;
       fhir:Element.id [ fhir:value "Observation.encounter" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.encounter" ] ;
       fhir:ElementDefinition.short [ fhir:value "Healthcare event during which this observation is made" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The healthcare event  (e.g. a patient and healthcare provider interaction) during which this observation is made." ] ;
       fhir:ElementDefinition.comment [ fhir:value "This will typically be the encounter the event occurred within, but some events may be initiated prior to or after the official completion of an encounter but still be tied to the context of the encounter (e.g. pre-admission laboratory tests)." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For some observations it may be important to know the link between an observation and a particular encounter." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "Context" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.encounter" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Reference" ] ;
         fhir:ElementDefinition.type.targetProfile [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Encounter|4.0.1" ;
           fhir:index 0 ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Encounter|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "workflow" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "Event.context" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.context" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "PV1" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "inboundRelationship[typeCode=COMP].source[classCode=ENC, moodCode=EVN]" ]
       ]
     ], [
       fhir:index 30 ;
       fhir:Element.id [ fhir:value "Observation.effective[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.effective[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "Clinically relevant time/time-period for observation" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The time or time-period the observed value is asserted as being true. For biological subjects - e.g. human patients - this is usually called the \"physiologically relevant time\". This is usually either the time of the procedure or of specimen collection, but very often the source of the date/time is not known, only the date/time itself." ] ;
       fhir:ElementDefinition.comment [ fhir:value "At least a date should be present unless this observation is a historical report.  For recording imprecise or \"fuzzy\" times (For example, a blood glucose measurement taken \"after breakfast\") use the [Timing](http://hl7.org/fhir/R4/datatypes.html#timing) datatype which allow the measurement to be tied to regular life events." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing when an observation was deemed true is important to its relevance as well as determining trends." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "Occurrence" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.effective[x]" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "dateTime" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.type.code [ fhir:value "Period" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.type.code [ fhir:value "Timing" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.type.code [ fhir:value "instant" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "workflow" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "Event.occurrence[x]" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.done[x]" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-14, and/or OBX-19 after v2.4  (depends on who observation made)" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "effectiveTime" ]
       ]
     ], [
       fhir:index 31 ;
       fhir:Element.id [ fhir:value "Observation.issued" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.issued" ] ;
       fhir:ElementDefinition.short [ fhir:value "Date/Time this version was made available" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The date and time this version of the observation was made available to providers, typically after the results have been reviewed and verified." ] ;
       fhir:ElementDefinition.comment [ fhir:value "For Observations that don’t require review and verification, it may be the same as the [`lastUpdated` ](http://hl7.org/fhir/R4/resource-definitions.html#Meta.lastUpdated) time of the resource itself.  For Observations that do require review and verification for certain updates, it might not be the same as the `lastUpdated` time of the resource itself due to a non-clinically significant update that doesn’t require the new version to be reviewed and verified again." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.issued" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "instant" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.recorded" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBR.22 (or MSH.7), or perhaps OBX-19 (depends on who observation made)" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "participation[typeCode=AUT].time" ]
       ]
     ], [
       fhir:index 32 ;
       fhir:Element.id [ fhir:value "Observation.performer" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.performer" ] ;
       fhir:ElementDefinition.short [ fhir:value "Who is responsible for the observation" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Who was responsible for asserting the observed value as \"true\"." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "May give a degree of confidence in the observation and also indicates where follow-up questions should be directed." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.performer" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Reference" ] ;
         fhir:ElementDefinition.type.targetProfile [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Practitioner|4.0.1" ;
           fhir:index 0 ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Practitioner|4.0.1>
         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/PractitionerRole|4.0.1" ;
           fhir:index 1 ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/PractitionerRole|4.0.1>
         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Organization|4.0.1" ;
           fhir:index 2 ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Organization|4.0.1>
         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/CareTeam|4.0.1" ;
           fhir:index 3 ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/CareTeam|4.0.1>
         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Patient|4.0.1" ;
           fhir:index 4 ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Patient|4.0.1>
         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/RelatedPerson|4.0.1" ;
           fhir:index 5 ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/RelatedPerson|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "workflow" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "Event.performer.actor" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.actor" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.15 / (Practitioner)  OBX-16,  PRT-5:PRT-4='RO' /  (Device)  OBX-18 , PRT-10:PRT-4='EQUIP' / (Organization)  OBX-23,  PRT-8:PRT-4='PO'" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "participation[typeCode=PRF]" ]
       ]
     ], [
       fhir:index 33 ;
       fhir:Element.id [ fhir:value "Observation.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.value[x]" ] ;
       fhir:ElementDefinition.slicing [
         fhir:ElementDefinition.slicing.discriminator [
           fhir:index 0 ;
           fhir:ElementDefinition.slicing.discriminator.type [ fhir:value "type" ] ;
           fhir:ElementDefinition.slicing.discriminator.path [ fhir:value "$this" ]
         ] ;
         fhir:ElementDefinition.slicing.ordered [ fhir:value "false"^^xsd:boolean ] ;
         fhir:ElementDefinition.slicing.rules [ fhir:value "closed" ]
       ] ;
       fhir:ElementDefinition.short [ fhir:value "Actual result" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ] ;
       fhir:ElementDefinition.comment [ fhir:value "An observation may have; 1)  a single value here, 2)  both a value and a set of related or component values,  or 3)  only a set of related or component values. If a value is present, the datatype for this element should be determined by Observation.code.  A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](http://hl7.org/fhir/R4/observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.value[x]" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Quantity" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.type.code [ fhir:value "string" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.type.code [ fhir:value "boolean" ]
       ], [
         fhir:index 4 ;
         fhir:ElementDefinition.type.code [ fhir:value "integer" ]
       ], [
         fhir:index 5 ;
         fhir:ElementDefinition.type.code [ fhir:value "Range" ]
       ], [
         fhir:index 6 ;
         fhir:ElementDefinition.type.code [ fhir:value "Ratio" ]
       ], [
         fhir:index 7 ;
         fhir:ElementDefinition.type.code [ fhir:value "SampledData" ]
       ], [
         fhir:index 8 ;
         fhir:ElementDefinition.type.code [ fhir:value "time" ]
       ], [
         fhir:index 9 ;
         fhir:ElementDefinition.type.code [ fhir:value "dateTime" ]
       ], [
         fhir:index 10 ;
         fhir:ElementDefinition.type.code [ fhir:value "Period" ]
       ] ;
       fhir:ElementDefinition.condition [
         fhir:value "obs-7" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 441742003 |Evaluation finding|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]
       ]
     ], [
       fhir:index 34 ;
       fhir:Element.id [ fhir:value "Observation.value[x]:valueCodeableConcept" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.value[x]" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "valueCodeableConcept" ] ;
       fhir:ElementDefinition.short [ fhir:value "Indeterminate | No call | Present | Absent." ] ;
       fhir:ElementDefinition.definition [ fhir:value "The presence or absence of the variant described in the components. If not searching for specific variations and merely reporting what's found, the profile's value should be set to 'Present'." ] ;
       fhir:ElementDefinition.comment [ fhir:value "See [here](sequencing.html#variant-assessment) for usage guidance." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.value[x]" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.condition [
         fhir:value "obs-7" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "required" ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://loinc.org/vs/LL1971-2" ;
           fhir:link <http://loinc.org/vs/LL1971-2>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 441742003 |Evaluation finding|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]
       ]
     ], [
       fhir:index 35 ;
       fhir:Element.id [ fhir:value "Observation.value[x]:valueQuantity" ] ;
       fhir:Element.extension [
         fhir:index 0 ;
         fhir:Extension.url [ fhir:value "http://hl7.org/fhir/tools/StructureDefinition/implied-type-slice" ] ;
         fhir:Extension.valueBoolean [ fhir:value "true"^^xsd:boolean ]
       ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.value[x]" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "valueQuantity" ] ;
       fhir:ElementDefinition.short [ fhir:value "Actual result" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ] ;
       fhir:ElementDefinition.comment [ fhir:value "An observation may have; 1)  a single value here, 2)  both a value and a set of related or component values,  or 3)  only a set of related or component values. If a value is present, the datatype for this element should be determined by Observation.code.  A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](http://hl7.org/fhir/R4/observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.value[x]" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Quantity" ]
       ] ;
       fhir:ElementDefinition.condition [
         fhir:value "obs-7" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 441742003 |Evaluation finding|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]
       ]
     ], [
       fhir:index 36 ;
       fhir:Element.id [ fhir:value "Observation.value[x]:valueString" ] ;
       fhir:Element.extension [
         fhir:index 0 ;
         fhir:Extension.url [ fhir:value "http://hl7.org/fhir/tools/StructureDefinition/implied-type-slice" ] ;
         fhir:Extension.valueBoolean [ fhir:value "true"^^xsd:boolean ]
       ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.value[x]" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "valueString" ] ;
       fhir:ElementDefinition.short [ fhir:value "Actual result" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ] ;
       fhir:ElementDefinition.comment [ fhir:value "An observation may have; 1)  a single value here, 2)  both a value and a set of related or component values,  or 3)  only a set of related or component values. If a value is present, the datatype for this element should be determined by Observation.code.  A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](http://hl7.org/fhir/R4/observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.value[x]" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "string" ]
       ] ;
       fhir:ElementDefinition.condition [
         fhir:value "obs-7" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 441742003 |Evaluation finding|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]
       ]
     ], [
       fhir:index 37 ;
       fhir:Element.id [ fhir:value "Observation.value[x]:valueBoolean" ] ;
       fhir:Element.extension [
         fhir:index 0 ;
         fhir:Extension.url [ fhir:value "http://hl7.org/fhir/tools/StructureDefinition/implied-type-slice" ] ;
         fhir:Extension.valueBoolean [ fhir:value "true"^^xsd:boolean ]
       ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.value[x]" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "valueBoolean" ] ;
       fhir:ElementDefinition.short [ fhir:value "Actual result" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ] ;
       fhir:ElementDefinition.comment [ fhir:value "An observation may have; 1)  a single value here, 2)  both a value and a set of related or component values,  or 3)  only a set of related or component values. If a value is present, the datatype for this element should be determined by Observation.code.  A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](http://hl7.org/fhir/R4/observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.value[x]" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "boolean" ]
       ] ;
       fhir:ElementDefinition.condition [
         fhir:value "obs-7" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 441742003 |Evaluation finding|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]
       ]
     ], [
       fhir:index 38 ;
       fhir:Element.id [ fhir:value "Observation.value[x]:valueInteger" ] ;
       fhir:Element.extension [
         fhir:index 0 ;
         fhir:Extension.url [ fhir:value "http://hl7.org/fhir/tools/StructureDefinition/implied-type-slice" ] ;
         fhir:Extension.valueBoolean [ fhir:value "true"^^xsd:boolean ]
       ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.value[x]" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "valueInteger" ] ;
       fhir:ElementDefinition.short [ fhir:value "Actual result" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ] ;
       fhir:ElementDefinition.comment [ fhir:value "An observation may have; 1)  a single value here, 2)  both a value and a set of related or component values,  or 3)  only a set of related or component values. If a value is present, the datatype for this element should be determined by Observation.code.  A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](http://hl7.org/fhir/R4/observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.value[x]" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "integer" ]
       ] ;
       fhir:ElementDefinition.condition [
         fhir:value "obs-7" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 441742003 |Evaluation finding|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]
       ]
     ], [
       fhir:index 39 ;
       fhir:Element.id [ fhir:value "Observation.value[x]:valueRange" ] ;
       fhir:Element.extension [
         fhir:index 0 ;
         fhir:Extension.url [ fhir:value "http://hl7.org/fhir/tools/StructureDefinition/implied-type-slice" ] ;
         fhir:Extension.valueBoolean [ fhir:value "true"^^xsd:boolean ]
       ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.value[x]" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "valueRange" ] ;
       fhir:ElementDefinition.short [ fhir:value "Actual result" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ] ;
       fhir:ElementDefinition.comment [ fhir:value "An observation may have; 1)  a single value here, 2)  both a value and a set of related or component values,  or 3)  only a set of related or component values. If a value is present, the datatype for this element should be determined by Observation.code.  A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](http://hl7.org/fhir/R4/observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.value[x]" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Range" ]
       ] ;
       fhir:ElementDefinition.condition [
         fhir:value "obs-7" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 441742003 |Evaluation finding|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]
       ]
     ], [
       fhir:index 40 ;
       fhir:Element.id [ fhir:value "Observation.value[x]:valueRatio" ] ;
       fhir:Element.extension [
         fhir:index 0 ;
         fhir:Extension.url [ fhir:value "http://hl7.org/fhir/tools/StructureDefinition/implied-type-slice" ] ;
         fhir:Extension.valueBoolean [ fhir:value "true"^^xsd:boolean ]
       ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.value[x]" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "valueRatio" ] ;
       fhir:ElementDefinition.short [ fhir:value "Actual result" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ] ;
       fhir:ElementDefinition.comment [ fhir:value "An observation may have; 1)  a single value here, 2)  both a value and a set of related or component values,  or 3)  only a set of related or component values. If a value is present, the datatype for this element should be determined by Observation.code.  A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](http://hl7.org/fhir/R4/observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.value[x]" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Ratio" ]
       ] ;
       fhir:ElementDefinition.condition [
         fhir:value "obs-7" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 441742003 |Evaluation finding|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]
       ]
     ], [
       fhir:index 41 ;
       fhir:Element.id [ fhir:value "Observation.value[x]:valueSampledData" ] ;
       fhir:Element.extension [
         fhir:index 0 ;
         fhir:Extension.url [ fhir:value "http://hl7.org/fhir/tools/StructureDefinition/implied-type-slice" ] ;
         fhir:Extension.valueBoolean [ fhir:value "true"^^xsd:boolean ]
       ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.value[x]" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "valueSampledData" ] ;
       fhir:ElementDefinition.short [ fhir:value "Actual result" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ] ;
       fhir:ElementDefinition.comment [ fhir:value "An observation may have; 1)  a single value here, 2)  both a value and a set of related or component values,  or 3)  only a set of related or component values. If a value is present, the datatype for this element should be determined by Observation.code.  A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](http://hl7.org/fhir/R4/observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.value[x]" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "SampledData" ]
       ] ;
       fhir:ElementDefinition.condition [
         fhir:value "obs-7" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 441742003 |Evaluation finding|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]
       ]
     ], [
       fhir:index 42 ;
       fhir:Element.id [ fhir:value "Observation.value[x]:valueTime" ] ;
       fhir:Element.extension [
         fhir:index 0 ;
         fhir:Extension.url [ fhir:value "http://hl7.org/fhir/tools/StructureDefinition/implied-type-slice" ] ;
         fhir:Extension.valueBoolean [ fhir:value "true"^^xsd:boolean ]
       ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.value[x]" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "valueTime" ] ;
       fhir:ElementDefinition.short [ fhir:value "Actual result" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ] ;
       fhir:ElementDefinition.comment [ fhir:value "An observation may have; 1)  a single value here, 2)  both a value and a set of related or component values,  or 3)  only a set of related or component values. If a value is present, the datatype for this element should be determined by Observation.code.  A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](http://hl7.org/fhir/R4/observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.value[x]" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "time" ]
       ] ;
       fhir:ElementDefinition.condition [
         fhir:value "obs-7" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 441742003 |Evaluation finding|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]
       ]
     ], [
       fhir:index 43 ;
       fhir:Element.id [ fhir:value "Observation.value[x]:valueDateTime" ] ;
       fhir:Element.extension [
         fhir:index 0 ;
         fhir:Extension.url [ fhir:value "http://hl7.org/fhir/tools/StructureDefinition/implied-type-slice" ] ;
         fhir:Extension.valueBoolean [ fhir:value "true"^^xsd:boolean ]
       ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.value[x]" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "valueDateTime" ] ;
       fhir:ElementDefinition.short [ fhir:value "Actual result" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ] ;
       fhir:ElementDefinition.comment [ fhir:value "An observation may have; 1)  a single value here, 2)  both a value and a set of related or component values,  or 3)  only a set of related or component values. If a value is present, the datatype for this element should be determined by Observation.code.  A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](http://hl7.org/fhir/R4/observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.value[x]" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "dateTime" ]
       ] ;
       fhir:ElementDefinition.condition [
         fhir:value "obs-7" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 441742003 |Evaluation finding|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]
       ]
     ], [
       fhir:index 44 ;
       fhir:Element.id [ fhir:value "Observation.value[x]:valuePeriod" ] ;
       fhir:Element.extension [
         fhir:index 0 ;
         fhir:Extension.url [ fhir:value "http://hl7.org/fhir/tools/StructureDefinition/implied-type-slice" ] ;
         fhir:Extension.valueBoolean [ fhir:value "true"^^xsd:boolean ]
       ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.value[x]" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "valuePeriod" ] ;
       fhir:ElementDefinition.short [ fhir:value "Actual result" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ] ;
       fhir:ElementDefinition.comment [ fhir:value "An observation may have; 1)  a single value here, 2)  both a value and a set of related or component values,  or 3)  only a set of related or component values. If a value is present, the datatype for this element should be determined by Observation.code.  A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](http://hl7.org/fhir/R4/observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.value[x]" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Period" ]
       ] ;
       fhir:ElementDefinition.condition [
         fhir:value "obs-7" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 441742003 |Evaluation finding|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]
       ]
     ], [
       fhir:index 45 ;
       fhir:Element.id [ fhir:value "Observation.dataAbsentReason" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.dataAbsentReason" ] ;
       fhir:ElementDefinition.short [ fhir:value "Why the result is missing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.value[x] is missing." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Null or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"specimen unsatisfactory\".   \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed. Note that an observation may only be reported if there are values to report. For example differential cell counts values may be reported only when > 0.  Because of these options, use-case agreements are required to interpret general observations for null or exceptional values." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.dataAbsentReason" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.condition [
         fhir:value "obs-6" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]
       ]
     ], [
       fhir:index 46 ;
       fhir:Element.id [ fhir:value "Observation.interpretation" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.interpretation" ] ;
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ] ;
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.interpretation" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]
       ]
     ], [
       fhir:index 47 ;
       fhir:Element.id [ fhir:value "Observation.note" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.note" ] ;
       fhir:ElementDefinition.short [ fhir:value "Comments about the Observation that also contain a coded type" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Comments about the observation or the results." ] ;
       fhir:ElementDefinition.comment [ fhir:value "May include general statements about the observation, or statements about significant, unexpected or unreliable results values, or information about its source when relevant to its interpretation.\nThe CodedAnnotation data type, while not allowing for or intending to make the content computable, does allow the author to indicate the type of note. This does not replace the use of interpretation, value, or component values.\nOne important note is that Annotation is a FHIR data type, this is **NOT** about annotations in the genomic context." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Need to be able to provide free text additional information. Notes SHALL NOT contain information which can be captured in a structured way." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.note" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Annotation" ] ;
         fhir:ElementDefinition.type.profile [
           fhir:value "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/coded-annotation" ;
           fhir:index 0 ;
           fhir:link <http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/coded-annotation> ;
           fhir:Element.extension [
             fhir:index 0 ;
             fhir:Extension.url [ fhir:value "http://hl7.org/fhir/tools/StructureDefinition/type-profile-constraints" ] ;
             fhir:Extension.valueCode [ fhir:value "full" ]
           ]
         ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "NTE.3 (partner NTE to OBX, or sometimes another (child?) OBX)" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "subjectOf.observationEvent[code=\"annotation\"].value" ]
       ]
     ], [
       fhir:index 48 ;
       fhir:Element.id [ fhir:value "Observation.bodySite" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.bodySite" ] ;
       fhir:ElementDefinition.short [ fhir:value "Observed body part" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Indicates the site on the subject's body where the observation was made (i.e. the target site)." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Only used if not implicit in code found in Observation.code.  In many systems, this may be represented as a related observation instead of an inline component.   \n\nIf the use case requires BodySite to be handled as a separate resource (e.g. to identify and track separately) then use the standard extension[ bodySite](http://hl7.org/fhir/R4/extension-bodysite.html)." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.bodySite" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "BodySite" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes describing anatomical locations. May include laterality." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/body-site|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/body-site|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 123037004 |Body structure|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-20" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "targetSiteCode" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "718497002 |Inherent location|" ]
       ]
     ], [
       fhir:index 49 ;
       fhir:Element.id [ fhir:value "Observation.method" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.method" ] ;
       fhir:ElementDefinition.short [ fhir:value "Sequencing | SNP array | PCR | Computational analysis | ..." ] ;
       fhir:ElementDefinition.definition [ fhir:value "Indicates the mechanism used to perform the observation." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Only used if not implicit in code for Observation.code." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "In some cases, method can impact results and is thus used for determining whether results can be compared or determining significance of results." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.method" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://loinc.org/vs/LL4048-6" ;
           fhir:link <http://loinc.org/vs/LL4048-6>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-17" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "methodCode" ]
       ]
     ], [
       fhir:index 50 ;
       fhir:Element.id [ fhir:value "Observation.specimen" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.specimen" ] ;
       fhir:ElementDefinition.short [ fhir:value "Specimen used for this observation" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The specimen that was used when this observation was made." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Should only be used if not implicit in code found in `Observation.code`.  Observations are not made on specimens themselves; they are made on a subject, but in many cases by the means of a specimen. Note that although specimens are often involved, they are not always tracked and reported explicitly. Also note that observation resources may be used in contexts that track the specimen explicitly (e.g. Diagnostic Report)." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.specimen" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Reference" ] ;
         fhir:ElementDefinition.type.targetProfile [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Specimen|4.0.1" ;
           fhir:index 0 ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Specimen|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 123038009 |Specimen|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "SPM segment" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "participation[typeCode=SPC].specimen" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "704319004 |Inherent in|" ]
       ]
     ], [
       fhir:index 51 ;
       fhir:Element.id [ fhir:value "Observation.device" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.device" ] ;
       fhir:ElementDefinition.short [ fhir:value "(Measurement) Device" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The device used to generate the observation data." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Note that this is not meant to represent a device involved in the transmission of the result, e.g., a gateway.  Such devices may be documented using the Provenance resource where relevant." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.device" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Reference" ] ;
         fhir:ElementDefinition.type.targetProfile [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Device|4.0.1" ;
           fhir:index 0 ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Device|4.0.1>
         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/DeviceMetric|4.0.1" ;
           fhir:index 1 ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/DeviceMetric|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 49062001 |Device|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-17 / PRT -10" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "participation[typeCode=DEV]" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "424226004 |Using device|" ]
       ]
     ], [
       fhir:index 52 ;
       fhir:Element.id [ fhir:value "Observation.referenceRange" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.referenceRange" ] ;
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range.  Multiple reference ranges are interpreted as an \"OR\".   In other words, to represent two distinct target populations, two `referenceRange` elements would be used." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.referenceRange" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "obs-3" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have at least a low or a high or text" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "low.exists() or high.exists() or text.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "(exists(f:low) or exists(f:high)or exists(f:text))" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Observation" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Observation>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]
       ]
     ], [
       fhir:index 53 ;
       fhir:Element.id [ fhir:value "Observation.referenceRange.id" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.referenceRange.id" ] ;
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ] ;
           fhir:Extension.valueUrl [ fhir:value "string" ]
         ] ;
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 54 ;
       fhir:Element.id [ fhir:value "Observation.referenceRange.extension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.referenceRange.extension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 55 ;
       fhir:Element.id [ fhir:value "Observation.referenceRange.modifierExtension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.referenceRange.modifierExtension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension)." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ], [
         fhir:value "modifiers" ;
         fhir:index 2
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ]
     ], [
       fhir:index 56 ;
       fhir:Element.id [ fhir:value "Observation.referenceRange.low" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.referenceRange.low" ] ;
       fhir:ElementDefinition.short [ fhir:value "Low Range, if relevant" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The value of the low bound of the reference range.  The low bound of the reference range endpoint is inclusive of the value (e.g.  reference range is >=5 - <=9). If the low bound is omitted,  it is assumed to be meaningless (e.g. reference range is <=2.3)." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.referenceRange.low" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Quantity" ] ;
         fhir:ElementDefinition.type.profile [
           fhir:value "http://hl7.org/fhir/StructureDefinition/SimpleQuantity|4.0.1" ;
           fhir:index 0 ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/SimpleQuantity|4.0.1> ;
           fhir:Element.extension [
             fhir:index 0 ;
             fhir:Extension.url [ fhir:value "http://hl7.org/fhir/tools/StructureDefinition/type-profile-constraints" ] ;
             fhir:Extension.valueCode [ fhir:value "full" ]
           ]
         ]
       ] ;
       fhir:ElementDefinition.condition [
         fhir:value "obs-3" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "sqty-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "The comparator is not used on a SimpleQuantity" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "comparator.empty()" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/SimpleQuantity" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/SimpleQuantity>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-7" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value:IVL_PQ.low" ]
       ]
     ], [
       fhir:index 57 ;
       fhir:Element.id [ fhir:value "Observation.referenceRange.high" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.referenceRange.high" ] ;
       fhir:ElementDefinition.short [ fhir:value "High Range, if relevant" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The value of the high bound of the reference range.  The high bound of the reference range endpoint is inclusive of the value (e.g.  reference range is >=5 - <=9). If the high bound is omitted,  it is assumed to be meaningless (e.g. reference range is >= 2.3)." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.referenceRange.high" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Quantity" ] ;
         fhir:ElementDefinition.type.profile [
           fhir:value "http://hl7.org/fhir/StructureDefinition/SimpleQuantity|4.0.1" ;
           fhir:index 0 ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/SimpleQuantity|4.0.1> ;
           fhir:Element.extension [
             fhir:index 0 ;
             fhir:Extension.url [ fhir:value "http://hl7.org/fhir/tools/StructureDefinition/type-profile-constraints" ] ;
             fhir:Extension.valueCode [ fhir:value "full" ]
           ]
         ]
       ] ;
       fhir:ElementDefinition.condition [
         fhir:value "obs-3" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "sqty-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "The comparator is not used on a SimpleQuantity" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "comparator.empty()" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/SimpleQuantity" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/SimpleQuantity>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-7" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value:IVL_PQ.high" ]
       ]
     ], [
       fhir:index 58 ;
       fhir:Element.id [ fhir:value "Observation.referenceRange.type" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.referenceRange.type" ] ;
       fhir:ElementDefinition.short [ fhir:value "Reference range qualifier" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Codes to indicate the what part of the targeted reference population it applies to. For example, the normal or therapeutic range." ] ;
       fhir:ElementDefinition.comment [ fhir:value "This SHOULD be populated if there is more than one range.  If this element is not present then the normal range is assumed." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Need to be able to say what kind of reference range this is - normal, recommended, therapeutic, etc.,  - for proper interpretation." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.referenceRange.type" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationRangeMeaning" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "preferred" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Code for the meaning of a reference range." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/referencerange-meaning|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/referencerange-meaning|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values| OR  \r< 365860008 |General clinical state finding| \rOR \r< 250171008 |Clinical history or observation findings| OR  \r< 415229000 |Racial group| OR \r< 365400002 |Finding of puberty stage| OR\r< 443938003 |Procedure carried out on subject|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-10" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]
       ]
     ], [
       fhir:index 59 ;
       fhir:Element.id [ fhir:value "Observation.referenceRange.appliesTo" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.referenceRange.appliesTo" ] ;
       fhir:ElementDefinition.short [ fhir:value "Reference range population" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Codes to indicate the target population this reference range applies to.  For example, a reference range may be based on the normal population or a particular sex or race.  Multiple `appliesTo`  are interpreted as an \"AND\" of the target populations.  For example, to represent a target population of African American females, both a code of female and a code for African American would be used." ] ;
       fhir:ElementDefinition.comment [ fhir:value "This SHOULD be populated if there is more than one range.  If this element is not present then the normal population is assumed." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Need to be able to identify the target population for proper interpretation." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.referenceRange.appliesTo" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationRangeType" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying the population the reference range applies to." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/referencerange-appliesto|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/referencerange-appliesto|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values| OR  \r< 365860008 |General clinical state finding| \rOR \r< 250171008 |Clinical history or observation findings| OR  \r< 415229000 |Racial group| OR \r< 365400002 |Finding of puberty stage| OR\r< 443938003 |Procedure carried out on subject|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-10" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]
       ]
     ], [
       fhir:index 60 ;
       fhir:Element.id [ fhir:value "Observation.referenceRange.age" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.referenceRange.age" ] ;
       fhir:ElementDefinition.short [ fhir:value "Applicable age range, if relevant" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The age at which this reference range is applicable. This is a neonatal age (e.g. number of weeks at term) if the meaning says so." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Some analytes vary greatly over age." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.referenceRange.age" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Range" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=PRCN].targetObservationCriterion[code=\"age\"].value" ]
       ]
     ], [
       fhir:index 61 ;
       fhir:Element.id [ fhir:value "Observation.referenceRange.text" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.referenceRange.text" ] ;
       fhir:ElementDefinition.short [ fhir:value "Text based reference range in an observation" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Text based reference range in an observation which may be used when a quantitative range is not appropriate for an observation.  An example would be a reference value of \"Negative\" or a list or table of \"normals\"." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.referenceRange.text" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "string" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-7" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value:ST" ]
       ]
     ], [
       fhir:index 62 ;
       fhir:Element.id [ fhir:value "Observation.hasMember" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.hasMember" ] ;
       fhir:ElementDefinition.short [ fhir:value "Related resource that belongs to the Observation group" ] ;
       fhir:ElementDefinition.definition [ fhir:value "This observation is a group observation (e.g. a battery, a panel of tests, a set of vital sign measurements) that includes the target as a member of the group." ] ;
       fhir:ElementDefinition.comment [ fhir:value "When using this element, an observation will typically have either a value or a set of related resources, although both may be present in some cases.  For a discussion on the ways Observations can assembled in groups together, see [Notes](http://hl7.org/fhir/R4/observation.html#obsgrouping) below.  Note that a system may calculate results from [QuestionnaireResponse](http://hl7.org/fhir/R4/questionnaireresponse.html)  into a final score and represent the score as an Observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.hasMember" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Reference" ] ;
         fhir:ElementDefinition.type.targetProfile [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Observation|4.0.1" ;
           fhir:index 0 ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Observation|4.0.1>
         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/QuestionnaireResponse|4.0.1" ;
           fhir:index 1 ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/QuestionnaireResponse|4.0.1>
         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/MolecularSequence|4.0.1" ;
           fhir:index 2 ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/MolecularSequence|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "Relationships established by OBX-4 usage" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship" ]
       ]
     ], [
       fhir:index 63 ;
       fhir:Element.id [ fhir:value "Observation.derivedFrom" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.derivedFrom" ] ;
       fhir:ElementDefinition.slicing [
         fhir:ElementDefinition.slicing.discriminator [
           fhir:index 0 ;
           fhir:ElementDefinition.slicing.discriminator.type [ fhir:value "profile" ] ;
           fhir:ElementDefinition.slicing.discriminator.path [ fhir:value "resolve()" ]
         ] ;
         fhir:ElementDefinition.slicing.description [ fhir:value "Slice based on the reference profile pattern" ] ;
         fhir:ElementDefinition.slicing.rules [ fhir:value "open" ]
       ] ;
       fhir:ElementDefinition.short [ fhir:value "Related measurements the observation is made from" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The target resource that represents a measurement from which this observation value is derived. For example, a calculated anion gap or a fetal measurement based on an ultrasound image." ] ;
       fhir:ElementDefinition.comment [ fhir:value "All the reference choices that are listed in this element can represent clinical observations and other measurements that may be the source for a derived value.  The most common reference will be another Observation.  For a discussion on the ways Observations can assembled in groups together, see [Notes](http://hl7.org/fhir/R4/observation.html#obsgrouping) below." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.derivedFrom" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Reference" ] ;
         fhir:ElementDefinition.type.targetProfile [
           fhir:value "http://hl7.org/fhir/StructureDefinition/DocumentReference|4.0.1" ;
           fhir:index 0 ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/DocumentReference|4.0.1>
         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/ImagingStudy|4.0.1" ;
           fhir:index 1 ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/ImagingStudy|4.0.1>
         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Media|4.0.1" ;
           fhir:index 2 ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Media|4.0.1>
         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/QuestionnaireResponse|4.0.1" ;
           fhir:index 3 ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/QuestionnaireResponse|4.0.1>
         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Observation|4.0.1" ;
           fhir:index 4 ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Observation|4.0.1>
         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/MolecularSequence|4.0.1" ;
           fhir:index 5 ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/MolecularSequence|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "Relationships established by OBX-4 usage" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value ".targetObservation" ]
       ]
     ], [
       fhir:index 64 ;
       fhir:Element.id [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.slicing [
         fhir:ElementDefinition.slicing.discriminator [
           fhir:index 0 ;
           fhir:ElementDefinition.slicing.discriminator.type [ fhir:value "value" ] ;
           fhir:ElementDefinition.slicing.discriminator.path [ fhir:value "code" ]
         ] ;
         fhir:ElementDefinition.slicing.description [ fhir:value "Slice based on the component.code pattern" ] ;
         fhir:ElementDefinition.slicing.rules [ fhir:value "open" ]
       ] ;
       fhir:ElementDefinition.short [ fhir:value "Component results" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Some observations have multiple component observations.  These component observations are expressed as separate code value pairs that share the same attributes.  Examples include systolic and diastolic component observations for blood pressure measurement and multiple component observations for genetics observations." ] ;
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](http://hl7.org/fhir/R4/observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]
       ]
     ], [
       fhir:index 65 ;
       fhir:Element.id [ fhir:value "Observation.component.id" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ] ;
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ] ;
           fhir:Extension.valueUrl [ fhir:value "string" ]
         ] ;
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 66 ;
       fhir:Element.id [ fhir:value "Observation.component.extension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 67 ;
       fhir:Element.id [ fhir:value "Observation.component.modifierExtension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension)." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ], [
         fhir:value "modifiers" ;
         fhir:index 2
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ]
     ], [
       fhir:index 68 ;
       fhir:Element.id [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "Type of component observation (code / type)" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ] ;
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]
       ]
     ], [
       fhir:index 69 ;
       fhir:Element.id [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "Actual component result" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](http://hl7.org/fhir/R4/observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Quantity" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.type.code [ fhir:value "string" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.type.code [ fhir:value "boolean" ]
       ], [
         fhir:index 4 ;
         fhir:ElementDefinition.type.code [ fhir:value "integer" ]
       ], [
         fhir:index 5 ;
         fhir:ElementDefinition.type.code [ fhir:value "Range" ]
       ], [
         fhir:index 6 ;
         fhir:ElementDefinition.type.code [ fhir:value "Ratio" ]
       ], [
         fhir:index 7 ;
         fhir:ElementDefinition.type.code [ fhir:value "SampledData" ]
       ], [
         fhir:index 8 ;
         fhir:ElementDefinition.type.code [ fhir:value "time" ]
       ], [
         fhir:index 9 ;
         fhir:ElementDefinition.type.code [ fhir:value "dateTime" ]
       ], [
         fhir:index 10 ;
         fhir:ElementDefinition.type.code [ fhir:value "Period" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]
       ]
     ], [
       fhir:index 70 ;
       fhir:Element.id [ fhir:value "Observation.component.dataAbsentReason" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ] ;
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.condition [
         fhir:value "obs-6" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]
       ]
     ], [
       fhir:index 71 ;
       fhir:Element.id [ fhir:value "Observation.component.interpretation" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ] ;
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ] ;
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]
       ]
     ], [
       fhir:index 72 ;
       fhir:Element.id [ fhir:value "Observation.component.referenceRange" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ] ;
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]
       ]
     ], [
       fhir:index 73 ;
       fhir:Element.id [ fhir:value "Observation.component:conclusion-string" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "conclusion-string" ] ;
       fhir:ElementDefinition.short [ fhir:value "Clinical Conclusion" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Concise and clinically contextualized summary conclusion (interpretation/impression) of the observation" ] ;
       fhir:ElementDefinition.comment [ fhir:value "An example would be the interpretative information, typically canned, about a variant identified in the patient." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Need to be able to provide a conclusion that is not lost among the basic result data." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]
       ]
     ], [
       fhir:index 74 ;
       fhir:Element.id [ fhir:value "Observation.component:conclusion-string.id" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ] ;
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ] ;
           fhir:Extension.valueUrl [ fhir:value "string" ]
         ] ;
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 75 ;
       fhir:Element.id [ fhir:value "Observation.component:conclusion-string.extension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 76 ;
       fhir:Element.id [ fhir:value "Observation.component:conclusion-string.modifierExtension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension)." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ], [
         fhir:value "modifiers" ;
         fhir:index 2
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ]
     ], [
       fhir:index 77 ;
       fhir:Element.id [ fhir:value "Observation.component:conclusion-string.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "conclusion-string" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ] ;
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           fhir:Coding.system [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs" ] ;
           fhir:Coding.code [ fhir:value "conclusion-string" ]
         ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]
       ]
     ], [
       fhir:index 78 ;
       fhir:Element.id [ fhir:value "Observation.component:conclusion-string.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "Summary conclusion (interpretation/impression)" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](http://hl7.org/fhir/R4/observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "string" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]
       ]
     ], [
       fhir:index 79 ;
       fhir:Element.id [ fhir:value "Observation.component:conclusion-string.dataAbsentReason" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ] ;
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.condition [
         fhir:value "obs-6" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]
       ]
     ], [
       fhir:index 80 ;
       fhir:Element.id [ fhir:value "Observation.component:conclusion-string.interpretation" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ] ;
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ] ;
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]
       ]
     ], [
       fhir:index 81 ;
       fhir:Element.id [ fhir:value "Observation.component:conclusion-string.referenceRange" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ] ;
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]
       ]
     ], [
       fhir:index 82 ;
       fhir:Element.id [ fhir:value "Observation.component:gene-studied" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "gene-studied" ] ;
       fhir:ElementDefinition.short [ fhir:value "Gene Studied" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The gene(s) on which the variant is located." ] ;
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]
       ]
     ], [
       fhir:index 83 ;
       fhir:Element.id [ fhir:value "Observation.component:gene-studied.id" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ] ;
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ] ;
           fhir:Extension.valueUrl [ fhir:value "string" ]
         ] ;
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 84 ;
       fhir:Element.id [ fhir:value "Observation.component:gene-studied.extension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 85 ;
       fhir:Element.id [ fhir:value "Observation.component:gene-studied.modifierExtension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension)." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ], [
         fhir:value "modifiers" ;
         fhir:index 2
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ]
     ], [
       fhir:index 86 ;
       fhir:Element.id [ fhir:value "Observation.component:gene-studied.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "48018-6" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ] ;
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           a loinc:48018-6 ;
           fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
           fhir:Coding.code [ fhir:value "48018-6" ]
         ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]
       ]
     ], [
       fhir:index 87 ;
       fhir:Element.id [ fhir:value "Observation.component:gene-studied.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "The HGNC gene symbol is to be used as display text and the HGNC gene ID used as the code. If no HGNC code issued for this gene yet, NCBI gene IDs SHALL be used." ] ;
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs" ;
           fhir:link <http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]
       ]
     ], [
       fhir:index 88 ;
       fhir:Element.id [ fhir:value "Observation.component:gene-studied.dataAbsentReason" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ] ;
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.condition [
         fhir:value "obs-6" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]
       ]
     ], [
       fhir:index 89 ;
       fhir:Element.id [ fhir:value "Observation.component:gene-studied.interpretation" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ] ;
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ] ;
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]
       ]
     ], [
       fhir:index 90 ;
       fhir:Element.id [ fhir:value "Observation.component:gene-studied.referenceRange" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ] ;
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]
       ]
     ], [
       fhir:index 91 ;
       fhir:Element.id [ fhir:value "Observation.component:cytogenetic-location" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "cytogenetic-location" ] ;
       fhir:ElementDefinition.short [ fhir:value "Cytogenetic (Chromosome) Location" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The relevant chromosomal region. The combination of numbers and letters provide a genetic 'address'." ] ;
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]
       ]
     ], [
       fhir:index 92 ;
       fhir:Element.id [ fhir:value "Observation.component:cytogenetic-location.id" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ] ;
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ] ;
           fhir:Extension.valueUrl [ fhir:value "string" ]
         ] ;
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 93 ;
       fhir:Element.id [ fhir:value "Observation.component:cytogenetic-location.extension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 94 ;
       fhir:Element.id [ fhir:value "Observation.component:cytogenetic-location.modifierExtension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension)." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ], [
         fhir:value "modifiers" ;
         fhir:index 2
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ]
     ], [
       fhir:index 95 ;
       fhir:Element.id [ fhir:value "Observation.component:cytogenetic-location.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "48001-2" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ] ;
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           a loinc:48001-2 ;
           fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
           fhir:Coding.code [ fhir:value "48001-2" ]
         ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]
       ]
     ], [
       fhir:index 96 ;
       fhir:Element.id [ fhir:value "Observation.component:cytogenetic-location.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "Example: 1q21.1" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]
       ]
     ], [
       fhir:index 97 ;
       fhir:Element.id [ fhir:value "Observation.component:cytogenetic-location.dataAbsentReason" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ] ;
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.condition [
         fhir:value "obs-6" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]
       ]
     ], [
       fhir:index 98 ;
       fhir:Element.id [ fhir:value "Observation.component:cytogenetic-location.interpretation" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ] ;
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ] ;
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]
       ]
     ], [
       fhir:index 99 ;
       fhir:Element.id [ fhir:value "Observation.component:cytogenetic-location.referenceRange" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ] ;
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]
       ]
     ], [
       fhir:index 100 ;
       fhir:Element.id [ fhir:value "Observation.component:reference-sequence-assembly" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "reference-sequence-assembly" ] ;
       fhir:ElementDefinition.short [ fhir:value "Human Reference Sequence Assembly" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The reference genome/assembly used in this analysis." ] ;
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]
       ]
     ], [
       fhir:index 101 ;
       fhir:Element.id [ fhir:value "Observation.component:reference-sequence-assembly.id" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ] ;
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ] ;
           fhir:Extension.valueUrl [ fhir:value "string" ]
         ] ;
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 102 ;
       fhir:Element.id [ fhir:value "Observation.component:reference-sequence-assembly.extension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 103 ;
       fhir:Element.id [ fhir:value "Observation.component:reference-sequence-assembly.modifierExtension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension)." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ], [
         fhir:value "modifiers" ;
         fhir:index 2
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ]
     ], [
       fhir:index 104 ;
       fhir:Element.id [ fhir:value "Observation.component:reference-sequence-assembly.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "62374-4" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ] ;
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           a loinc:62374-4 ;
           fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
           fhir:Coding.code [ fhir:value "62374-4" ]
         ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]
       ]
     ], [
       fhir:index 105 ;
       fhir:Element.id [ fhir:value "Observation.component:reference-sequence-assembly.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "GRCh37 | GRCh38 | ..." ] ;
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://loinc.org/vs/LL1040-6" ;
           fhir:link <http://loinc.org/vs/LL1040-6>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]
       ]
     ], [
       fhir:index 106 ;
       fhir:Element.id [ fhir:value "Observation.component:reference-sequence-assembly.dataAbsentReason" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ] ;
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.condition [
         fhir:value "obs-6" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]
       ]
     ], [
       fhir:index 107 ;
       fhir:Element.id [ fhir:value "Observation.component:reference-sequence-assembly.interpretation" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ] ;
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ] ;
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]
       ]
     ], [
       fhir:index 108 ;
       fhir:Element.id [ fhir:value "Observation.component:reference-sequence-assembly.referenceRange" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ] ;
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]
       ]
     ], [
       fhir:index 109 ;
       fhir:Element.id [ fhir:value "Observation.component:chromosome-identifier" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "chromosome-identifier" ] ;
       fhir:ElementDefinition.short [ fhir:value "Chromosome Identifier" ] ;
       fhir:ElementDefinition.definition [ fhir:value "An indicator, enumerated in humans by numbers 1-22, X, and Y, representing the chromosome on which the finding is located." ] ;
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]
       ]
     ], [
       fhir:index 110 ;
       fhir:Element.id [ fhir:value "Observation.component:chromosome-identifier.id" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ] ;
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ] ;
           fhir:Extension.valueUrl [ fhir:value "string" ]
         ] ;
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 111 ;
       fhir:Element.id [ fhir:value "Observation.component:chromosome-identifier.extension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 112 ;
       fhir:Element.id [ fhir:value "Observation.component:chromosome-identifier.modifierExtension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension)." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ], [
         fhir:value "modifiers" ;
         fhir:index 2
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ]
     ], [
       fhir:index 113 ;
       fhir:Element.id [ fhir:value "Observation.component:chromosome-identifier.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "48000-4" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ] ;
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           a loinc:48000-4 ;
           fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
           fhir:Coding.code [ fhir:value "48000-4" ]
         ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]
       ]
     ], [
       fhir:index 114 ;
       fhir:Element.id [ fhir:value "Observation.component:chromosome-identifier.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "Chromosome 1 | Chromosome 2 | ... | Chromosome 22 | Chromosome X | Chromosome Y" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "required" ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://loinc.org/vs/LL2938-0" ;
           fhir:link <http://loinc.org/vs/LL2938-0>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]
       ]
     ], [
       fhir:index 115 ;
       fhir:Element.id [ fhir:value "Observation.component:chromosome-identifier.dataAbsentReason" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ] ;
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.condition [
         fhir:value "obs-6" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]
       ]
     ], [
       fhir:index 116 ;
       fhir:Element.id [ fhir:value "Observation.component:chromosome-identifier.interpretation" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ] ;
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ] ;
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]
       ]
     ], [
       fhir:index 117 ;
       fhir:Element.id [ fhir:value "Observation.component:chromosome-identifier.referenceRange" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ] ;
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]
       ]
     ], [
       fhir:index 118 ;
       fhir:Element.id [ fhir:value "Observation.component:representative-coding-hgvs" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "representative-coding-hgvs" ] ;
       fhir:ElementDefinition.short [ fhir:value "DNA change (c.HGVS)" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Human Genome Variation Society (HGVS) nomenclature for a single DNA marker. The use of the nomenclature must be extended to describe non-variations (aka. wild types) see samples for wild type examples." ] ;
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]
       ]
     ], [
       fhir:index 119 ;
       fhir:Element.id [ fhir:value "Observation.component:representative-coding-hgvs.id" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ] ;
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ] ;
           fhir:Extension.valueUrl [ fhir:value "string" ]
         ] ;
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 120 ;
       fhir:Element.id [ fhir:value "Observation.component:representative-coding-hgvs.extension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 121 ;
       fhir:Element.id [ fhir:value "Observation.component:representative-coding-hgvs.modifierExtension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension)." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ], [
         fhir:value "modifiers" ;
         fhir:index 2
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ]
     ], [
       fhir:index 122 ;
       fhir:Element.id [ fhir:value "Observation.component:representative-coding-hgvs.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "48004-6" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ] ;
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           a loinc:48004-6 ;
           fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
           fhir:Coding.code [ fhir:value "48004-6" ]
         ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]
       ]
     ], [
       fhir:index 123 ;
       fhir:Element.id [ fhir:value "Observation.component:representative-coding-hgvs.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "A valid HGVS-formatted 'c.' string, e.g. NM_005228.5:c.2369C>T." ] ;
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "required" ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs" ;
           fhir:link <http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]
       ]
     ], [
       fhir:index 124 ;
       fhir:Element.id [ fhir:value "Observation.component:representative-coding-hgvs.dataAbsentReason" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ] ;
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.condition [
         fhir:value "obs-6" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]
       ]
     ], [
       fhir:index 125 ;
       fhir:Element.id [ fhir:value "Observation.component:representative-coding-hgvs.interpretation" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ] ;
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ] ;
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]
       ]
     ], [
       fhir:index 126 ;
       fhir:Element.id [ fhir:value "Observation.component:representative-coding-hgvs.referenceRange" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ] ;
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]
       ]
     ], [
       fhir:index 127 ;
       fhir:Element.id [ fhir:value "Observation.component:genomic-hgvs" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "genomic-hgvs" ] ;
       fhir:ElementDefinition.short [ fhir:value "Genomic (gDNA) Change - gHGVS" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Description of the genomic (gDNA) sequence change using a valid HGVS-formatted string." ] ;
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]
       ]
     ], [
       fhir:index 128 ;
       fhir:Element.id [ fhir:value "Observation.component:genomic-hgvs.id" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ] ;
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ] ;
           fhir:Extension.valueUrl [ fhir:value "string" ]
         ] ;
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 129 ;
       fhir:Element.id [ fhir:value "Observation.component:genomic-hgvs.extension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 130 ;
       fhir:Element.id [ fhir:value "Observation.component:genomic-hgvs.modifierExtension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension)." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ], [
         fhir:value "modifiers" ;
         fhir:index 2
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ]
     ], [
       fhir:index 131 ;
       fhir:Element.id [ fhir:value "Observation.component:genomic-hgvs.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "81290-9" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ] ;
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           a loinc:81290-9 ;
           fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
           fhir:Coding.code [ fhir:value "81290-9" ]
         ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]
       ]
     ], [
       fhir:index 132 ;
       fhir:Element.id [ fhir:value "Observation.component:genomic-hgvs.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "A valid HGVS-formatted 'g.' string, e.g. NC_000016.9:g.2124200_2138612dup" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "required" ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs" ;
           fhir:link <http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]
       ]
     ], [
       fhir:index 133 ;
       fhir:Element.id [ fhir:value "Observation.component:genomic-hgvs.dataAbsentReason" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ] ;
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.condition [
         fhir:value "obs-6" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]
       ]
     ], [
       fhir:index 134 ;
       fhir:Element.id [ fhir:value "Observation.component:genomic-hgvs.interpretation" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ] ;
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ] ;
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]
       ]
     ], [
       fhir:index 135 ;
       fhir:Element.id [ fhir:value "Observation.component:genomic-hgvs.referenceRange" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ] ;
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]
       ]
     ], [
       fhir:index 136 ;
       fhir:Element.id [ fhir:value "Observation.component:cytogenomic-nomenclature" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "cytogenomic-nomenclature" ] ;
       fhir:ElementDefinition.short [ fhir:value "Cytogenomic Nomenclature (ISCN)" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Fully describes a variant with a single code. Typically a large variant such as a mosaic, abnormal chromosome numbers, etc." ] ;
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]
       ]
     ], [
       fhir:index 137 ;
       fhir:Element.id [ fhir:value "Observation.component:cytogenomic-nomenclature.id" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ] ;
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ] ;
           fhir:Extension.valueUrl [ fhir:value "string" ]
         ] ;
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 138 ;
       fhir:Element.id [ fhir:value "Observation.component:cytogenomic-nomenclature.extension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 139 ;
       fhir:Element.id [ fhir:value "Observation.component:cytogenomic-nomenclature.modifierExtension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension)." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ], [
         fhir:value "modifiers" ;
         fhir:index 2
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ]
     ], [
       fhir:index 140 ;
       fhir:Element.id [ fhir:value "Observation.component:cytogenomic-nomenclature.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "81291-7" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ] ;
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           a loinc:81291-7 ;
           fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
           fhir:Coding.code [ fhir:value "81291-7" ]
         ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]
       ]
     ], [
       fhir:index 141 ;
       fhir:Element.id [ fhir:value "Observation.component:cytogenomic-nomenclature.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "Actual component result" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Binding not yet defined" ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]
       ]
     ], [
       fhir:index 142 ;
       fhir:Element.id [ fhir:value "Observation.component:cytogenomic-nomenclature.dataAbsentReason" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ] ;
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.condition [
         fhir:value "obs-6" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]
       ]
     ], [
       fhir:index 143 ;
       fhir:Element.id [ fhir:value "Observation.component:cytogenomic-nomenclature.interpretation" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ] ;
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ] ;
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]
       ]
     ], [
       fhir:index 144 ;
       fhir:Element.id [ fhir:value "Observation.component:cytogenomic-nomenclature.referenceRange" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ] ;
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]
       ]
     ], [
       fhir:index 145 ;
       fhir:Element.id [ fhir:value "Observation.component:genomic-ref-seq" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "genomic-ref-seq" ] ;
       fhir:ElementDefinition.short [ fhir:value "Genomic Reference Sequence" ] ;
       fhir:ElementDefinition.definition [ fhir:value "ID of the genomic reference sequence, which includes transcribed and non transcribed stretches" ] ;
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]
       ]
     ], [
       fhir:index 146 ;
       fhir:Element.id [ fhir:value "Observation.component:genomic-ref-seq.id" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ] ;
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ] ;
           fhir:Extension.valueUrl [ fhir:value "string" ]
         ] ;
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 147 ;
       fhir:Element.id [ fhir:value "Observation.component:genomic-ref-seq.extension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 148 ;
       fhir:Element.id [ fhir:value "Observation.component:genomic-ref-seq.modifierExtension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension)." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ], [
         fhir:value "modifiers" ;
         fhir:index 2
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ]
     ], [
       fhir:index 149 ;
       fhir:Element.id [ fhir:value "Observation.component:genomic-ref-seq.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "48013-7" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ] ;
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           a loinc:48013-7 ;
           fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
           fhir:Coding.code [ fhir:value "48013-7" ]
         ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]
       ]
     ], [
       fhir:index 150 ;
       fhir:Element.id [ fhir:value "Observation.component:genomic-ref-seq.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "Versioned genomic reference sequence identifier" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Multiple bindings acceptable (NCBI or LRG)" ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]
       ]
     ], [
       fhir:index 151 ;
       fhir:Element.id [ fhir:value "Observation.component:genomic-ref-seq.dataAbsentReason" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ] ;
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.condition [
         fhir:value "obs-6" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]
       ]
     ], [
       fhir:index 152 ;
       fhir:Element.id [ fhir:value "Observation.component:genomic-ref-seq.interpretation" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ] ;
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ] ;
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]
       ]
     ], [
       fhir:index 153 ;
       fhir:Element.id [ fhir:value "Observation.component:genomic-ref-seq.referenceRange" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ] ;
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]
       ]
     ], [
       fhir:index 154 ;
       fhir:Element.id [ fhir:value "Observation.component:representative-protein-ref-seq" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "representative-protein-ref-seq" ] ;
       fhir:ElementDefinition.short [ fhir:value "Protein Reference Sequence" ] ;
       fhir:ElementDefinition.definition [ fhir:value "ID of the protein reference sequence, which includes transcribed and non transcribed stretches. It covers the entire protein described." ] ;
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]
       ]
     ], [
       fhir:index 155 ;
       fhir:Element.id [ fhir:value "Observation.component:representative-protein-ref-seq.id" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ] ;
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ] ;
           fhir:Extension.valueUrl [ fhir:value "string" ]
         ] ;
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 156 ;
       fhir:Element.id [ fhir:value "Observation.component:representative-protein-ref-seq.extension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 157 ;
       fhir:Element.id [ fhir:value "Observation.component:representative-protein-ref-seq.modifierExtension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension)." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ], [
         fhir:value "modifiers" ;
         fhir:index 2
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ]
     ], [
       fhir:index 158 ;
       fhir:Element.id [ fhir:value "Observation.component:representative-protein-ref-seq.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "protein-ref-seq" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ] ;
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           fhir:Coding.system [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs" ] ;
           fhir:Coding.code [ fhir:value "protein-ref-seq" ]
         ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]
       ]
     ], [
       fhir:index 159 ;
       fhir:Element.id [ fhir:value "Observation.component:representative-protein-ref-seq.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "Versioned protein reference sequence identifier" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Multiple bindings acceptable (NCBI or LRG)" ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]
       ]
     ], [
       fhir:index 160 ;
       fhir:Element.id [ fhir:value "Observation.component:representative-protein-ref-seq.dataAbsentReason" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ] ;
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.condition [
         fhir:value "obs-6" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]
       ]
     ], [
       fhir:index 161 ;
       fhir:Element.id [ fhir:value "Observation.component:representative-protein-ref-seq.interpretation" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ] ;
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ] ;
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]
       ]
     ], [
       fhir:index 162 ;
       fhir:Element.id [ fhir:value "Observation.component:representative-protein-ref-seq.referenceRange" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ] ;
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]
       ]
     ], [
       fhir:index 163 ;
       fhir:Element.id [ fhir:value "Observation.component:representative-transcript-ref-seq" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "representative-transcript-ref-seq" ] ;
       fhir:ElementDefinition.short [ fhir:value "Reference Transcript" ] ;
       fhir:ElementDefinition.definition [ fhir:value "NCBI's RefSeq ('NM_...'), Ensembl ('ENST...'), and LRG ('LRG...' plus 't1' to indicate transcript)" ] ;
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]
       ]
     ], [
       fhir:index 164 ;
       fhir:Element.id [ fhir:value "Observation.component:representative-transcript-ref-seq.id" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ] ;
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ] ;
           fhir:Extension.valueUrl [ fhir:value "string" ]
         ] ;
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 165 ;
       fhir:Element.id [ fhir:value "Observation.component:representative-transcript-ref-seq.extension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 166 ;
       fhir:Element.id [ fhir:value "Observation.component:representative-transcript-ref-seq.modifierExtension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension)." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ], [
         fhir:value "modifiers" ;
         fhir:index 2
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ]
     ], [
       fhir:index 167 ;
       fhir:Element.id [ fhir:value "Observation.component:representative-transcript-ref-seq.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "51958-7" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ] ;
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           a loinc:51958-7 ;
           fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
           fhir:Coding.code [ fhir:value "51958-7" ]
         ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]
       ]
     ], [
       fhir:index 168 ;
       fhir:Element.id [ fhir:value "Observation.component:representative-transcript-ref-seq.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "Versioned transcript reference sequence identifier" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Multiple bindings acceptable (NCBI or LRG)" ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]
       ]
     ], [
       fhir:index 169 ;
       fhir:Element.id [ fhir:value "Observation.component:representative-transcript-ref-seq.dataAbsentReason" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ] ;
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.condition [
         fhir:value "obs-6" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]
       ]
     ], [
       fhir:index 170 ;
       fhir:Element.id [ fhir:value "Observation.component:representative-transcript-ref-seq.interpretation" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ] ;
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ] ;
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]
       ]
     ], [
       fhir:index 171 ;
       fhir:Element.id [ fhir:value "Observation.component:representative-transcript-ref-seq.referenceRange" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ] ;
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]
       ]
     ], [
       fhir:index 172 ;
       fhir:Element.id [ fhir:value "Observation.component:exact-start-end" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "exact-start-end" ] ;
       fhir:ElementDefinition.short [ fhir:value "Exact Start-End" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The exact integer-based genomic coordinates of the start and end of the variant region." ] ;
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]
       ]
     ], [
       fhir:index 173 ;
       fhir:Element.id [ fhir:value "Observation.component:exact-start-end.id" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ] ;
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ] ;
           fhir:Extension.valueUrl [ fhir:value "string" ]
         ] ;
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 174 ;
       fhir:Element.id [ fhir:value "Observation.component:exact-start-end.extension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 175 ;
       fhir:Element.id [ fhir:value "Observation.component:exact-start-end.modifierExtension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension)." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ], [
         fhir:value "modifiers" ;
         fhir:index 2
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ]
     ], [
       fhir:index 176 ;
       fhir:Element.id [ fhir:value "Observation.component:exact-start-end.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "81254-5" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ] ;
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           a loinc:81254-5 ;
           fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
           fhir:Coding.code [ fhir:value "81254-5" ]
         ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]
       ]
     ], [
       fhir:index 177 ;
       fhir:Element.id [ fhir:value "Observation.component:exact-start-end.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "Range in question. 'High' can be omitted for single nucleotide variants." ] ;
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Range" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]
       ]
     ], [
       fhir:index 178 ;
       fhir:Element.id [ fhir:value "Observation.component:exact-start-end.dataAbsentReason" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ] ;
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.condition [
         fhir:value "obs-6" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]
       ]
     ], [
       fhir:index 179 ;
       fhir:Element.id [ fhir:value "Observation.component:exact-start-end.interpretation" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ] ;
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ] ;
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]
       ]
     ], [
       fhir:index 180 ;
       fhir:Element.id [ fhir:value "Observation.component:exact-start-end.referenceRange" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ] ;
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]
       ]
     ], [
       fhir:index 181 ;
       fhir:Element.id [ fhir:value "Observation.component:inner-start-end" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "inner-start-end" ] ;
       fhir:ElementDefinition.short [ fhir:value "Inner Start-End" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The genomic coordinates of the narrowest genomic range in which the variant might reside. Used when the exact boundaries of the variant are not clear." ] ;
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]
       ]
     ], [
       fhir:index 182 ;
       fhir:Element.id [ fhir:value "Observation.component:inner-start-end.id" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ] ;
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ] ;
           fhir:Extension.valueUrl [ fhir:value "string" ]
         ] ;
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 183 ;
       fhir:Element.id [ fhir:value "Observation.component:inner-start-end.extension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 184 ;
       fhir:Element.id [ fhir:value "Observation.component:inner-start-end.modifierExtension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension)." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ], [
         fhir:value "modifiers" ;
         fhir:index 2
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ]
     ], [
       fhir:index 185 ;
       fhir:Element.id [ fhir:value "Observation.component:inner-start-end.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "81302-2" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ] ;
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           a loinc:81302-2 ;
           fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
           fhir:Coding.code [ fhir:value "81302-2" ]
         ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]
       ]
     ], [
       fhir:index 186 ;
       fhir:Element.id [ fhir:value "Observation.component:inner-start-end.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "Imprecise variant inner-bounding range" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Range" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]
       ]
     ], [
       fhir:index 187 ;
       fhir:Element.id [ fhir:value "Observation.component:inner-start-end.dataAbsentReason" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ] ;
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.condition [
         fhir:value "obs-6" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]
       ]
     ], [
       fhir:index 188 ;
       fhir:Element.id [ fhir:value "Observation.component:inner-start-end.interpretation" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ] ;
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ] ;
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]
       ]
     ], [
       fhir:index 189 ;
       fhir:Element.id [ fhir:value "Observation.component:inner-start-end.referenceRange" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ] ;
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]
       ]
     ], [
       fhir:index 190 ;
       fhir:Element.id [ fhir:value "Observation.component:outer-start-end" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "outer-start-end" ] ;
       fhir:ElementDefinition.short [ fhir:value "Outer Start-End" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The genomic coordinates of the widest genomic range in which the variant might reside. Used when the exact boundaries of the variant are not clear." ] ;
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]
       ]
     ], [
       fhir:index 191 ;
       fhir:Element.id [ fhir:value "Observation.component:outer-start-end.id" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ] ;
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ] ;
           fhir:Extension.valueUrl [ fhir:value "string" ]
         ] ;
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 192 ;
       fhir:Element.id [ fhir:value "Observation.component:outer-start-end.extension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 193 ;
       fhir:Element.id [ fhir:value "Observation.component:outer-start-end.modifierExtension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension)." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ], [
         fhir:value "modifiers" ;
         fhir:index 2
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ]
     ], [
       fhir:index 194 ;
       fhir:Element.id [ fhir:value "Observation.component:outer-start-end.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "81301-4" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ] ;
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           a loinc:81301-4 ;
           fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
           fhir:Coding.code [ fhir:value "81301-4" ]
         ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]
       ]
     ], [
       fhir:index 195 ;
       fhir:Element.id [ fhir:value "Observation.component:outer-start-end.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "Imprecise variant outer-bounding range" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Range" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]
       ]
     ], [
       fhir:index 196 ;
       fhir:Element.id [ fhir:value "Observation.component:outer-start-end.dataAbsentReason" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ] ;
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.condition [
         fhir:value "obs-6" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]
       ]
     ], [
       fhir:index 197 ;
       fhir:Element.id [ fhir:value "Observation.component:outer-start-end.interpretation" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ] ;
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ] ;
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]
       ]
     ], [
       fhir:index 198 ;
       fhir:Element.id [ fhir:value "Observation.component:outer-start-end.referenceRange" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ] ;
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]
       ]
     ], [
       fhir:index 199 ;
       fhir:Element.id [ fhir:value "Observation.component:coordinate-system" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "coordinate-system" ] ;
       fhir:ElementDefinition.short [ fhir:value "Coordinate System" ] ;
       fhir:ElementDefinition.definition [ fhir:value "These are different ways of identifying nucleotides or amino acids within a sequence. In the 1-based system, the first unit of the polymer (e.g. the first nucleotide) is counted as number 1. In the 0-based system, the number 0 designates the location before the first nucleotide. Different databases and file types may use different systems." ] ;
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]
       ]
     ], [
       fhir:index 200 ;
       fhir:Element.id [ fhir:value "Observation.component:coordinate-system.id" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ] ;
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ] ;
           fhir:Extension.valueUrl [ fhir:value "string" ]
         ] ;
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 201 ;
       fhir:Element.id [ fhir:value "Observation.component:coordinate-system.extension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 202 ;
       fhir:Element.id [ fhir:value "Observation.component:coordinate-system.modifierExtension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension)." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ], [
         fhir:value "modifiers" ;
         fhir:index 2
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ]
     ], [
       fhir:index 203 ;
       fhir:Element.id [ fhir:value "Observation.component:coordinate-system.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "92822-6" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ] ;
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           a loinc:92822-6 ;
           fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
           fhir:Coding.code [ fhir:value "92822-6" ]
         ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]
       ]
     ], [
       fhir:index 204 ;
       fhir:Element.id [ fhir:value "Observation.component:coordinate-system.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "0-based interval counting | 0-based character counting | 1-based character counting" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://loinc.org/vs/LL5323-2" ;
           fhir:link <http://loinc.org/vs/LL5323-2>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]
       ]
     ], [
       fhir:index 205 ;
       fhir:Element.id [ fhir:value "Observation.component:coordinate-system.dataAbsentReason" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ] ;
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.condition [
         fhir:value "obs-6" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]
       ]
     ], [
       fhir:index 206 ;
       fhir:Element.id [ fhir:value "Observation.component:coordinate-system.interpretation" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ] ;
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ] ;
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]
       ]
     ], [
       fhir:index 207 ;
       fhir:Element.id [ fhir:value "Observation.component:coordinate-system.referenceRange" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ] ;
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]
       ]
     ], [
       fhir:index 208 ;
       fhir:Element.id [ fhir:value "Observation.component:ref-allele" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "ref-allele" ] ;
       fhir:ElementDefinition.short [ fhir:value "Genomic Ref Allele" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Reference values ('normal') examined within the Reference Sequence." ] ;
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]
       ]
     ], [
       fhir:index 209 ;
       fhir:Element.id [ fhir:value "Observation.component:ref-allele.id" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ] ;
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ] ;
           fhir:Extension.valueUrl [ fhir:value "string" ]
         ] ;
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 210 ;
       fhir:Element.id [ fhir:value "Observation.component:ref-allele.extension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 211 ;
       fhir:Element.id [ fhir:value "Observation.component:ref-allele.modifierExtension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension)." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ], [
         fhir:value "modifiers" ;
         fhir:index 2
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ]
     ], [
       fhir:index 212 ;
       fhir:Element.id [ fhir:value "Observation.component:ref-allele.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "69547-8" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ] ;
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           a loinc:69547-8 ;
           fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
           fhir:Coding.code [ fhir:value "69547-8" ]
         ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]
       ]
     ], [
       fhir:index 213 ;
       fhir:Element.id [ fhir:value "Observation.component:ref-allele.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "Normalized string per the VCF format." ] ;
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "string" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]
       ]
     ], [
       fhir:index 214 ;
       fhir:Element.id [ fhir:value "Observation.component:ref-allele.dataAbsentReason" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ] ;
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.condition [
         fhir:value "obs-6" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]
       ]
     ], [
       fhir:index 215 ;
       fhir:Element.id [ fhir:value "Observation.component:ref-allele.interpretation" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ] ;
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ] ;
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]
       ]
     ], [
       fhir:index 216 ;
       fhir:Element.id [ fhir:value "Observation.component:ref-allele.referenceRange" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ] ;
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]
       ]
     ], [
       fhir:index 217 ;
       fhir:Element.id [ fhir:value "Observation.component:alt-allele" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "alt-allele" ] ;
       fhir:ElementDefinition.short [ fhir:value "Genomic Alt Allele" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The genomic alternate allele is the contiguous segment of DNA in the test sample that differs from the reference allele at the same location and thus defines a variant." ] ;
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]
       ]
     ], [
       fhir:index 218 ;
       fhir:Element.id [ fhir:value "Observation.component:alt-allele.id" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ] ;
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ] ;
           fhir:Extension.valueUrl [ fhir:value "string" ]
         ] ;
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 219 ;
       fhir:Element.id [ fhir:value "Observation.component:alt-allele.extension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 220 ;
       fhir:Element.id [ fhir:value "Observation.component:alt-allele.modifierExtension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension)." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ], [
         fhir:value "modifiers" ;
         fhir:index 2
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ]
     ], [
       fhir:index 221 ;
       fhir:Element.id [ fhir:value "Observation.component:alt-allele.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "69551-0" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ] ;
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           a loinc:69551-0 ;
           fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
           fhir:Coding.code [ fhir:value "69551-0" ]
         ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]
       ]
     ], [
       fhir:index 222 ;
       fhir:Element.id [ fhir:value "Observation.component:alt-allele.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "Normalized string per the VCF format." ] ;
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "string" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]
       ]
     ], [
       fhir:index 223 ;
       fhir:Element.id [ fhir:value "Observation.component:alt-allele.dataAbsentReason" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ] ;
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.condition [
         fhir:value "obs-6" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]
       ]
     ], [
       fhir:index 224 ;
       fhir:Element.id [ fhir:value "Observation.component:alt-allele.interpretation" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ] ;
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ] ;
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]
       ]
     ], [
       fhir:index 225 ;
       fhir:Element.id [ fhir:value "Observation.component:alt-allele.referenceRange" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ] ;
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]
       ]
     ], [
       fhir:index 226 ;
       fhir:Element.id [ fhir:value "Observation.component:coding-change-type" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "coding-change-type" ] ;
       fhir:ElementDefinition.short [ fhir:value "Coding DNA Change Type" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Type of DNA change observed. Convenience property for variants with exact breakpoints, required otherwise." ] ;
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]
       ]
     ], [
       fhir:index 227 ;
       fhir:Element.id [ fhir:value "Observation.component:coding-change-type.id" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ] ;
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ] ;
           fhir:Extension.valueUrl [ fhir:value "string" ]
         ] ;
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 228 ;
       fhir:Element.id [ fhir:value "Observation.component:coding-change-type.extension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 229 ;
       fhir:Element.id [ fhir:value "Observation.component:coding-change-type.modifierExtension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension)." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ], [
         fhir:value "modifiers" ;
         fhir:index 2
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ]
     ], [
       fhir:index 230 ;
       fhir:Element.id [ fhir:value "Observation.component:coding-change-type.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "48019-4" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ] ;
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           a loinc:48019-4 ;
           fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
           fhir:Coding.code [ fhir:value "48019-4" ]
         ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]
       ]
     ], [
       fhir:index 231 ;
       fhir:Element.id [ fhir:value "Observation.component:coding-change-type.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "deletion | insertion | delins | SNV | copy_number_gain | copy_number_loss | ... (many)" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Concepts in sequence ontology under SO:0002072" ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs" ;
           fhir:link <http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]
       ]
     ], [
       fhir:index 232 ;
       fhir:Element.id [ fhir:value "Observation.component:coding-change-type.dataAbsentReason" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ] ;
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.condition [
         fhir:value "obs-6" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]
       ]
     ], [
       fhir:index 233 ;
       fhir:Element.id [ fhir:value "Observation.component:coding-change-type.interpretation" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ] ;
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ] ;
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]
       ]
     ], [
       fhir:index 234 ;
       fhir:Element.id [ fhir:value "Observation.component:coding-change-type.referenceRange" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ] ;
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]
       ]
     ], [
       fhir:index 235 ;
       fhir:Element.id [ fhir:value "Observation.component:genomic-source-class" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "genomic-source-class" ] ;
       fhir:ElementDefinition.short [ fhir:value "Genomic Source Class" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The genomic class of the specimen being analyzed: Germline for inherited genome, somatic for cancer genome, and prenatal for fetal genome." ] ;
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]
       ]
     ], [
       fhir:index 236 ;
       fhir:Element.id [ fhir:value "Observation.component:genomic-source-class.id" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ] ;
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ] ;
           fhir:Extension.valueUrl [ fhir:value "string" ]
         ] ;
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 237 ;
       fhir:Element.id [ fhir:value "Observation.component:genomic-source-class.extension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 238 ;
       fhir:Element.id [ fhir:value "Observation.component:genomic-source-class.modifierExtension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension)." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ], [
         fhir:value "modifiers" ;
         fhir:index 2
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ]
     ], [
       fhir:index 239 ;
       fhir:Element.id [ fhir:value "Observation.component:genomic-source-class.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "48002-0" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ] ;
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           a loinc:48002-0 ;
           fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
           fhir:Coding.code [ fhir:value "48002-0" ]
         ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]
       ]
     ], [
       fhir:index 240 ;
       fhir:Element.id [ fhir:value "Observation.component:genomic-source-class.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "Germline | Somatic | Fetal | Likely germline | Likely somatic | Likely fetal | Unknown genomic origin | De novo" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://loinc.org/vs/LL378-1" ;
           fhir:link <http://loinc.org/vs/LL378-1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]
       ]
     ], [
       fhir:index 241 ;
       fhir:Element.id [ fhir:value "Observation.component:genomic-source-class.dataAbsentReason" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ] ;
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.condition [
         fhir:value "obs-6" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]
       ]
     ], [
       fhir:index 242 ;
       fhir:Element.id [ fhir:value "Observation.component:genomic-source-class.interpretation" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ] ;
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ] ;
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]
       ]
     ], [
       fhir:index 243 ;
       fhir:Element.id [ fhir:value "Observation.component:genomic-source-class.referenceRange" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ] ;
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]
       ]
     ], [
       fhir:index 244 ;
       fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "sample-allelic-frequency" ] ;
       fhir:ElementDefinition.short [ fhir:value "Sample Allelic Frequency" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The relative frequency of the allele at a given locus in the sample." ] ;
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]
       ]
     ], [
       fhir:index 245 ;
       fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.id" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ] ;
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ] ;
           fhir:Extension.valueUrl [ fhir:value "string" ]
         ] ;
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 246 ;
       fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.extension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 247 ;
       fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.modifierExtension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension)." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ], [
         fhir:value "modifiers" ;
         fhir:index 2
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ]
     ], [
       fhir:index 248 ;
       fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "81258-6" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ] ;
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           a loinc:81258-6 ;
           fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
           fhir:Coding.code [ fhir:value "81258-6" ]
         ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]
       ]
     ], [
       fhir:index 249 ;
       fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "Relative frequency in the sample" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Quantity" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]
       ]
     ], [
       fhir:index 250 ;
       fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.value[x].id" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x].id" ] ;
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ] ;
           fhir:Extension.valueUrl [ fhir:value "string" ]
         ] ;
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 251 ;
       fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.value[x].extension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x].extension" ] ;
       fhir:ElementDefinition.slicing [
         fhir:ElementDefinition.slicing.discriminator [
           fhir:index 0 ;
           fhir:ElementDefinition.slicing.discriminator.type [ fhir:value "value" ] ;
           fhir:ElementDefinition.slicing.discriminator.path [ fhir:value "url" ]
         ] ;
         fhir:ElementDefinition.slicing.description [ fhir:value "Extensions are always sliced by (at least) url" ] ;
         fhir:ElementDefinition.slicing.rules [ fhir:value "open" ]
       ] ;
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 252 ;
       fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.value[x].value" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x].value" ] ;
       fhir:ElementDefinition.short [ fhir:value "Numerical value (with implicit precision)" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The value of the measured amount. The value includes an implicit precision in the presentation of the value." ] ;
       fhir:ElementDefinition.comment [ fhir:value "The implicit precision in the value should always be honored. Monetary values have their own rules for handling precision (refer to standard accounting text books)." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Precision is handled implicitly in almost all cases of measurement." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Quantity.value" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "decimal" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "SN.2  / CQ - N/A" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "PQ.value, CO.value, MO.value, IVL.high or IVL.low depending on the value" ]
       ]
     ], [
       fhir:index 253 ;
       fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.value[x].comparator" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x].comparator" ] ;
       fhir:ElementDefinition.short [ fhir:value "< | <= | >= | > - how to understand the value" ] ;
       fhir:ElementDefinition.definition [ fhir:value "How the value should be understood and represented - whether the actual value is greater or less than the stated value due to measurement issues; e.g. if the comparator is \"<\" , then the real value is < stated value." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Need a framework for handling measures where the value is <5ug/L or >400mg/L due to the limitations of measuring methodology." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Quantity.comparator" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "code" ]
       ] ;
       fhir:ElementDefinition.meaningWhenMissing [ fhir:value "If there is no comparator, then there is no modification of the value" ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.isModifierReason [ fhir:value "This is labeled as \"Is Modifier\" because the comparator modifies the interpretation of the value significantly. If there is no comparator, then there is no modification of the value" ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "QuantityComparator" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "required" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "How the Quantity should be understood and represented." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/quantity-comparator|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/quantity-comparator|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "SN.1  / CQ.1" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "IVL properties" ]
       ]
     ], [
       fhir:index 254 ;
       fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.value[x].unit" ] ;
       fhir:Element.extension [
         fhir:index 0 ;
         fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-translatable" ] ;
         fhir:Extension.valueBoolean [ fhir:value "true"^^xsd:boolean ]
       ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x].unit" ] ;
       fhir:ElementDefinition.short [ fhir:value "Unit representation" ] ;
       fhir:ElementDefinition.definition [ fhir:value "A human-readable form of the unit." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "There are many representations for units of measure and in many contexts, particular representations are fixed and required. I.e. mcg for micrograms." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Quantity.unit" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "string" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "(see OBX.6 etc.) / CQ.2" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "PQ.unit" ]
       ]
     ], [
       fhir:index 255 ;
       fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.value[x].system" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x].system" ] ;
       fhir:ElementDefinition.short [ fhir:value "System that defines coded unit form" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The identification of the system that provides the coded form of the unit." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Need to know the system that defines the coded form of the unit." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Quantity.system" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "uri" ]
       ] ;
       fhir:ElementDefinition.patternUri [ fhir:value "http://unitsofmeasure.org" ] ;
       fhir:ElementDefinition.condition [
         fhir:value "qty-3" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "(see OBX.6 etc.) / CQ.2" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "CO.codeSystem, PQ.translation.codeSystem" ]
       ]
     ], [
       fhir:index 256 ;
       fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.value[x].code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x].code" ] ;
       fhir:ElementDefinition.short [ fhir:value "Coded form of the unit" ] ;
       fhir:ElementDefinition.definition [ fhir:value "A computer processable form of the unit in some unit representation system." ] ;
       fhir:ElementDefinition.comment [ fhir:value "The preferred system is UCUM, but SNOMED CT can also be used (for customary units) or ISO 4217 for currency.  The context of use may additionally require a code from a particular system." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Need a computable form of the unit that is fixed across all forms. UCUM provides this for quantities, but SNOMED CT provides many units of interest." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Quantity.code" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "code" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "(see OBX.6 etc.) / CQ.2" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "PQ.code, MO.currency, PQ.translation.code" ]
       ]
     ], [
       fhir:index 257 ;
       fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.dataAbsentReason" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ] ;
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.condition [
         fhir:value "obs-6" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]
       ]
     ], [
       fhir:index 258 ;
       fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.interpretation" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ] ;
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ] ;
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]
       ]
     ], [
       fhir:index 259 ;
       fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.referenceRange" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ] ;
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]
       ]
     ], [
       fhir:index 260 ;
       fhir:Element.id [ fhir:value "Observation.component:allelic-read-depth" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "allelic-read-depth" ] ;
       fhir:ElementDefinition.short [ fhir:value "Allelic Read Depth" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Specifies the number of reads that identified the allele in question whether it consists of one or a small sequence of contiguous nucleotides. Different methods and purposes require different numbers of reads to be acceptable. Often >400, sometimes as few as 2-4." ] ;
       fhir:ElementDefinition.comment [ fhir:value "See [here](sequencing.html#variant-assessment) for usage guidance." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]
       ]
     ], [
       fhir:index 261 ;
       fhir:Element.id [ fhir:value "Observation.component:allelic-read-depth.id" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ] ;
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ] ;
           fhir:Extension.valueUrl [ fhir:value "string" ]
         ] ;
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 262 ;
       fhir:Element.id [ fhir:value "Observation.component:allelic-read-depth.extension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 263 ;
       fhir:Element.id [ fhir:value "Observation.component:allelic-read-depth.modifierExtension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension)." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ], [
         fhir:value "modifiers" ;
         fhir:index 2
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ]
     ], [
       fhir:index 264 ;
       fhir:Element.id [ fhir:value "Observation.component:allelic-read-depth.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "82121-5" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ] ;
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           a loinc:82121-5 ;
           fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
           fhir:Coding.code [ fhir:value "82121-5" ]
         ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]
       ]
     ], [
       fhir:index 265 ;
       fhir:Element.id [ fhir:value "Observation.component:allelic-read-depth.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "Unfiltered count of supporting reads" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Quantity" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]
       ]
     ], [
       fhir:index 266 ;
       fhir:Element.id [ fhir:value "Observation.component:allelic-read-depth.dataAbsentReason" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ] ;
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.condition [
         fhir:value "obs-6" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]
       ]
     ], [
       fhir:index 267 ;
       fhir:Element.id [ fhir:value "Observation.component:allelic-read-depth.interpretation" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ] ;
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ] ;
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]
       ]
     ], [
       fhir:index 268 ;
       fhir:Element.id [ fhir:value "Observation.component:allelic-read-depth.referenceRange" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ] ;
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]
       ]
     ], [
       fhir:index 269 ;
       fhir:Element.id [ fhir:value "Observation.component:allelic-state" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "allelic-state" ] ;
       fhir:ElementDefinition.short [ fhir:value "Allelic State" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The observed level of occurrence of the variant in the set of chromosomes." ] ;
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]
       ]
     ], [
       fhir:index 270 ;
       fhir:Element.id [ fhir:value "Observation.component:allelic-state.id" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ] ;
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ] ;
           fhir:Extension.valueUrl [ fhir:value "string" ]
         ] ;
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 271 ;
       fhir:Element.id [ fhir:value "Observation.component:allelic-state.extension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 272 ;
       fhir:Element.id [ fhir:value "Observation.component:allelic-state.modifierExtension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension)." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ], [
         fhir:value "modifiers" ;
         fhir:index 2
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ]
     ], [
       fhir:index 273 ;
       fhir:Element.id [ fhir:value "Observation.component:allelic-state.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "53034-5" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ] ;
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           a loinc:53034-5 ;
           fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
           fhir:Coding.code [ fhir:value "53034-5" ]
         ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]
       ]
     ], [
       fhir:index 274 ;
       fhir:Element.id [ fhir:value "Observation.component:allelic-state.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "Heteroplasmic | Homoplasmic | Homozygous | Heterozygous | Hemizygous" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://loinc.org/vs/LL381-5" ;
           fhir:link <http://loinc.org/vs/LL381-5>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]
       ]
     ], [
       fhir:index 275 ;
       fhir:Element.id [ fhir:value "Observation.component:allelic-state.dataAbsentReason" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ] ;
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.condition [
         fhir:value "obs-6" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]
       ]
     ], [
       fhir:index 276 ;
       fhir:Element.id [ fhir:value "Observation.component:allelic-state.interpretation" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ] ;
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ] ;
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]
       ]
     ], [
       fhir:index 277 ;
       fhir:Element.id [ fhir:value "Observation.component:allelic-state.referenceRange" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ] ;
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]
       ]
     ], [
       fhir:index 278 ;
       fhir:Element.id [ fhir:value "Observation.component:variant-inheritance" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "variant-inheritance" ] ;
       fhir:ElementDefinition.short [ fhir:value "Origin of germline genetic variant" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The source or inheritance of a specific germline variation found in an individual patient." ] ;
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]
       ]
     ], [
       fhir:index 279 ;
       fhir:Element.id [ fhir:value "Observation.component:variant-inheritance.id" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ] ;
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ] ;
           fhir:Extension.valueUrl [ fhir:value "string" ]
         ] ;
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 280 ;
       fhir:Element.id [ fhir:value "Observation.component:variant-inheritance.extension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 281 ;
       fhir:Element.id [ fhir:value "Observation.component:variant-inheritance.modifierExtension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension)." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ], [
         fhir:value "modifiers" ;
         fhir:index 2
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ]
     ], [
       fhir:index 282 ;
       fhir:Element.id [ fhir:value "Observation.component:variant-inheritance.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "94186-4" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ] ;
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           a loinc:94186-4 ;
           fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
           fhir:Coding.code [ fhir:value "94186-4" ]
         ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]
       ]
     ], [
       fhir:index 283 ;
       fhir:Element.id [ fhir:value "Observation.component:variant-inheritance.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "Maternal | Paternal | Unknown" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://loinc.org/vs/LL5489-1" ;
           fhir:link <http://loinc.org/vs/LL5489-1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]
       ]
     ], [
       fhir:index 284 ;
       fhir:Element.id [ fhir:value "Observation.component:variant-inheritance.dataAbsentReason" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ] ;
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.condition [
         fhir:value "obs-6" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]
       ]
     ], [
       fhir:index 285 ;
       fhir:Element.id [ fhir:value "Observation.component:variant-inheritance.interpretation" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ] ;
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ] ;
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]
       ]
     ], [
       fhir:index 286 ;
       fhir:Element.id [ fhir:value "Observation.component:variant-inheritance.referenceRange" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ] ;
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]
       ]
     ], [
       fhir:index 287 ;
       fhir:Element.id [ fhir:value "Observation.component:variant-inheritance-basis" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "variant-inheritance-basis" ] ;
       fhir:ElementDefinition.short [ fhir:value "Evidential basis for variant inheritance" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The method by which the variant inheritance is determined." ] ;
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]
       ]
     ], [
       fhir:index 288 ;
       fhir:Element.id [ fhir:value "Observation.component:variant-inheritance-basis.id" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ] ;
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ] ;
           fhir:Extension.valueUrl [ fhir:value "string" ]
         ] ;
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 289 ;
       fhir:Element.id [ fhir:value "Observation.component:variant-inheritance-basis.extension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 290 ;
       fhir:Element.id [ fhir:value "Observation.component:variant-inheritance-basis.modifierExtension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension)." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ], [
         fhir:value "modifiers" ;
         fhir:index 2
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ]
     ], [
       fhir:index 291 ;
       fhir:Element.id [ fhir:value "Observation.component:variant-inheritance-basis.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "Basis for allelic phase" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ] ;
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           a loinc:82309-6 ;
           fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
           fhir:Coding.code [ fhir:value "82309-6" ]
         ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]
       ]
     ], [
       fhir:index 292 ;
       fhir:Element.id [ fhir:value "Observation.component:variant-inheritance-basis.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "Directly measured | Family DNA | Family history | Inferred from population data" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://loinc.org/vs/LL4050-2" ;
           fhir:link <http://loinc.org/vs/LL4050-2>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]
       ]
     ], [
       fhir:index 293 ;
       fhir:Element.id [ fhir:value "Observation.component:variant-inheritance-basis.dataAbsentReason" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ] ;
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.condition [
         fhir:value "obs-6" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]
       ]
     ], [
       fhir:index 294 ;
       fhir:Element.id [ fhir:value "Observation.component:variant-inheritance-basis.interpretation" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ] ;
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ] ;
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]
       ]
     ], [
       fhir:index 295 ;
       fhir:Element.id [ fhir:value "Observation.component:variant-inheritance-basis.referenceRange" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ] ;
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]
       ]
     ], [
       fhir:index 296 ;
       fhir:Element.id [ fhir:value "Observation.component:variation-code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "variation-code" ] ;
       fhir:ElementDefinition.short [ fhir:value "Variation Code" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Accession number in a variant database such as ClinVar, given for cross-reference." ] ;
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]
       ]
     ], [
       fhir:index 297 ;
       fhir:Element.id [ fhir:value "Observation.component:variation-code.id" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ] ;
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ] ;
           fhir:Extension.valueUrl [ fhir:value "string" ]
         ] ;
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 298 ;
       fhir:Element.id [ fhir:value "Observation.component:variation-code.extension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 299 ;
       fhir:Element.id [ fhir:value "Observation.component:variation-code.modifierExtension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension)." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ], [
         fhir:value "modifiers" ;
         fhir:index 2
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ]
     ], [
       fhir:index 300 ;
       fhir:Element.id [ fhir:value "Observation.component:variation-code.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "81252-9" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ] ;
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           a loinc:81252-9 ;
           fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
           fhir:Coding.code [ fhir:value "81252-9" ]
         ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]
       ]
     ], [
       fhir:index 301 ;
       fhir:Element.id [ fhir:value "Observation.component:variation-code.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "ClinVar ID or similar" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Multiple bindings acceptable" ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]
       ]
     ], [
       fhir:index 302 ;
       fhir:Element.id [ fhir:value "Observation.component:variation-code.dataAbsentReason" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ] ;
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.condition [
         fhir:value "obs-6" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]
       ]
     ], [
       fhir:index 303 ;
       fhir:Element.id [ fhir:value "Observation.component:variation-code.interpretation" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ] ;
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ] ;
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]
       ]
     ], [
       fhir:index 304 ;
       fhir:Element.id [ fhir:value "Observation.component:variation-code.referenceRange" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ] ;
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]
       ]
     ], [
       fhir:index 305 ;
       fhir:Element.id [ fhir:value "Observation.component:representative-protein-hgvs" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "representative-protein-hgvs" ] ;
       fhir:ElementDefinition.short [ fhir:value "Protein (Amino Acid) Change - pHGVS" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Description of the protein (amino acid) sequence change using a valid HGVS-formatted string. The description of the variant is surrounded in parentheses if it is calculated rather than directly observed." ] ;
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]
       ]
     ], [
       fhir:index 306 ;
       fhir:Element.id [ fhir:value "Observation.component:representative-protein-hgvs.id" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ] ;
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ] ;
           fhir:Extension.valueUrl [ fhir:value "string" ]
         ] ;
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 307 ;
       fhir:Element.id [ fhir:value "Observation.component:representative-protein-hgvs.extension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 308 ;
       fhir:Element.id [ fhir:value "Observation.component:representative-protein-hgvs.modifierExtension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension)." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ], [
         fhir:value "modifiers" ;
         fhir:index 2
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ]
     ], [
       fhir:index 309 ;
       fhir:Element.id [ fhir:value "Observation.component:representative-protein-hgvs.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "48005-3" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ] ;
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           a loinc:48005-3 ;
           fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
           fhir:Coding.code [ fhir:value "48005-3" ]
         ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]
       ]
     ], [
       fhir:index 310 ;
       fhir:Element.id [ fhir:value "Observation.component:representative-protein-hgvs.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "A valid HGVS-formatted 'p.' string, e.g. NP_000050.2:p.(Asn1836Lys)" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "required" ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs" ;
           fhir:link <http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]
       ]
     ], [
       fhir:index 311 ;
       fhir:Element.id [ fhir:value "Observation.component:representative-protein-hgvs.dataAbsentReason" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ] ;
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.condition [
         fhir:value "obs-6" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]
       ]
     ], [
       fhir:index 312 ;
       fhir:Element.id [ fhir:value "Observation.component:representative-protein-hgvs.interpretation" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ] ;
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ] ;
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]
       ]
     ], [
       fhir:index 313 ;
       fhir:Element.id [ fhir:value "Observation.component:representative-protein-hgvs.referenceRange" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ] ;
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]
       ]
     ], [
       fhir:index 314 ;
       fhir:Element.id [ fhir:value "Observation.component:copy-number" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "copy-number" ] ;
       fhir:ElementDefinition.short [ fhir:value "Genomic Structural Variant Copy Number" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The copy number of the large variant. In HGVS, this is the numeric value following the “X”. It is a unit-less value. If the value determined by the assay is not a whole number, a range or decimal number can be specified. Note that a copy number of 1 can imply a deletion." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Copy number variants are often described with a single copy number value. However, due to the nature of assays, such as qPCR and microarray, it can be difficult to assign an exact copy number. Therefore, labs sometimes report a range instead of an exact copy number. They may alternatively choose to report decimal numbers, even if whole numbers are biologically correct.\n\nIn general, it can be difficult to estimate a copy number from measurements taken on a heterogenous population of cells, such as a tumor. As indicated in the ISCN 2020 specifications, it is appropriate to express the measurements using a range. Furthermore, regardless of cell population, many assays use fluorescent probes to detect copy number. These testing methodologies do not always provide an exact, discrete value for this data point." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "There SHALL be a code with a value of '1' if there is a value. If system is present, it SHALL be UCUM." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]
       ]
     ], [
       fhir:index 315 ;
       fhir:Element.id [ fhir:value "Observation.component:copy-number.id" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ] ;
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ] ;
           fhir:Extension.valueUrl [ fhir:value "string" ]
         ] ;
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 316 ;
       fhir:Element.id [ fhir:value "Observation.component:copy-number.extension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 317 ;
       fhir:Element.id [ fhir:value "Observation.component:copy-number.modifierExtension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension)." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ], [
         fhir:value "modifiers" ;
         fhir:index 2
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ]
     ], [
       fhir:index 318 ;
       fhir:Element.id [ fhir:value "Observation.component:copy-number.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "82155-3" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ] ;
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           a loinc:82155-3 ;
           fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
           fhir:Coding.code [ fhir:value "82155-3" ]
         ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]
       ]
     ], [
       fhir:index 319 ;
       fhir:Element.id [ fhir:value "Observation.component:copy-number.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "Actual component result" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Quantity" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.type.code [ fhir:value "Range" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]
       ]
     ], [
       fhir:index 320 ;
       fhir:Element.id [ fhir:value "Observation.component:copy-number.dataAbsentReason" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ] ;
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.condition [
         fhir:value "obs-6" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]
       ]
     ], [
       fhir:index 321 ;
       fhir:Element.id [ fhir:value "Observation.component:copy-number.interpretation" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ] ;
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ] ;
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]
       ]
     ], [
       fhir:index 322 ;
       fhir:Element.id [ fhir:value "Observation.component:copy-number.referenceRange" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ] ;
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]
       ]
     ], [
       fhir:index 323 ;
       fhir:Element.id [ fhir:value "Observation.component:variant-confidence-status" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "variant-confidence-status" ] ;
       fhir:ElementDefinition.short [ fhir:value "Variant Confidence Status" ] ;
       fhir:ElementDefinition.definition [ fhir:value "A code that represents the confidence of a true positive variant call." ] ;
       fhir:ElementDefinition.comment [ fhir:value "See [here](sequencing.html#variant-assessment) for usage guidance." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]
       ]
     ], [
       fhir:index 324 ;
       fhir:Element.id [ fhir:value "Observation.component:variant-confidence-status.id" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ] ;
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ] ;
           fhir:Extension.valueUrl [ fhir:value "string" ]
         ] ;
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 325 ;
       fhir:Element.id [ fhir:value "Observation.component:variant-confidence-status.extension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 326 ;
       fhir:Element.id [ fhir:value "Observation.component:variant-confidence-status.modifierExtension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension)." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ], [
         fhir:value "modifiers" ;
         fhir:index 2
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ]
     ], [
       fhir:index 327 ;
       fhir:Element.id [ fhir:value "Observation.component:variant-confidence-status.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "variant-confidence-status" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ] ;
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           fhir:Coding.system [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs" ] ;
           fhir:Coding.code [ fhir:value "variant-confidence-status" ]
         ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]
       ]
     ], [
       fhir:index 328 ;
       fhir:Element.id [ fhir:value "Observation.component:variant-confidence-status.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "High | Intermediate | Low" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "required" ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/uv/genomics-reporting/ValueSet/variant-confidence-status-vs" ;
           fhir:link <http://hl7.org/fhir/uv/genomics-reporting/ValueSet/variant-confidence-status-vs>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]
       ]
     ], [
       fhir:index 329 ;
       fhir:Element.id [ fhir:value "Observation.component:variant-confidence-status.dataAbsentReason" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ] ;
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.condition [
         fhir:value "obs-6" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]
       ]
     ], [
       fhir:index 330 ;
       fhir:Element.id [ fhir:value "Observation.component:variant-confidence-status.interpretation" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ] ;
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ] ;
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]
       ]
     ], [
       fhir:index 331 ;
       fhir:Element.id [ fhir:value "Observation.component:variant-confidence-status.referenceRange" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ] ;
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]
       ]
     ], [
       fhir:index 332 ;
       fhir:Element.id [ fhir:value "Observation.component:repeat-motif" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "repeat-motif" ] ;
       fhir:ElementDefinition.short [ fhir:value "Repeat Motif" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Nucleotides of a repeat expansion motif." ] ;
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]
       ]
     ], [
       fhir:index 333 ;
       fhir:Element.id [ fhir:value "Observation.component:repeat-motif.id" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ] ;
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ] ;
           fhir:Extension.valueUrl [ fhir:value "string" ]
         ] ;
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 334 ;
       fhir:Element.id [ fhir:value "Observation.component:repeat-motif.extension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ] ;
       fhir:ElementDefinition.slicing [
         fhir:ElementDefinition.slicing.discriminator [
           fhir:index 0 ;
           fhir:ElementDefinition.slicing.discriminator.type [ fhir:value "value" ] ;
           fhir:ElementDefinition.slicing.discriminator.path [ fhir:value "url" ]
         ] ;
         fhir:ElementDefinition.slicing.ordered [ fhir:value "false"^^xsd:boolean ] ;
         fhir:ElementDefinition.slicing.rules [ fhir:value "open" ]
       ] ;
       fhir:ElementDefinition.short [ fhir:value "Extension" ] ;
       fhir:ElementDefinition.definition [ fhir:value "An Extension" ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]
     ], [
       fhir:index 335 ;
       fhir:Element.id [ fhir:value "Observation.component:repeat-motif.extension:repeat-motif-order" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "repeat-motif-order" ] ;
       fhir:ElementDefinition.short [ fhir:value "Repeat Motif Order" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Use to group and order repeat expansion motifs." ] ;
       fhir:ElementDefinition.comment [ fhir:value "If there are multiple repeat expansion pairs, this must be used both to indicate the sequence position of a given repeat-motif and repeat-number pair and to group the related components together. Components with the same extension value describe the same motif." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "The value must be a natural number starting from 1 and increasing sequentially" ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ;
         fhir:ElementDefinition.type.profile [
           fhir:value "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/repeat-motif-order" ;
           fhir:index 0 ;
           fhir:link <http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/repeat-motif-order>
         ]
       ] ;
       fhir:ElementDefinition.condition [
         fhir:value "ele-1" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]
     ], [
       fhir:index 336 ;
       fhir:Element.id [ fhir:value "Observation.component:repeat-motif.modifierExtension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension)." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ], [
         fhir:value "modifiers" ;
         fhir:index 2
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ]
     ], [
       fhir:index 337 ;
       fhir:Element.id [ fhir:value "Observation.component:repeat-motif.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "repeat-motif" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ] ;
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           fhir:Coding.system [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs" ] ;
           fhir:Coding.code [ fhir:value "repeat-motif" ]
         ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]
       ]
     ], [
       fhir:index 338 ;
       fhir:Element.id [ fhir:value "Observation.component:repeat-motif.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "CAG" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "string" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]
       ]
     ], [
       fhir:index 339 ;
       fhir:Element.id [ fhir:value "Observation.component:repeat-motif.dataAbsentReason" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ] ;
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.condition [
         fhir:value "obs-6" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]
       ]
     ], [
       fhir:index 340 ;
       fhir:Element.id [ fhir:value "Observation.component:repeat-motif.interpretation" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ] ;
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ] ;
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]
       ]
     ], [
       fhir:index 341 ;
       fhir:Element.id [ fhir:value "Observation.component:repeat-motif.referenceRange" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ] ;
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]
       ]
     ], [
       fhir:index 342 ;
       fhir:Element.id [ fhir:value "Observation.component:repeat-number" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "repeat-number" ] ;
       fhir:ElementDefinition.short [ fhir:value "Repeat Number" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Number of repeats of a repeat expansion." ] ;
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]
       ]
     ], [
       fhir:index 343 ;
       fhir:Element.id [ fhir:value "Observation.component:repeat-number.id" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ] ;
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ] ;
           fhir:Extension.valueUrl [ fhir:value "string" ]
         ] ;
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]
       ]
     ], [
       fhir:index 344 ;
       fhir:Element.id [ fhir:value "Observation.component:repeat-number.extension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ] ;
       fhir:ElementDefinition.slicing [
         fhir:ElementDefinition.slicing.discriminator [
           fhir:index 0 ;
           fhir:ElementDefinition.slicing.discriminator.type [ fhir:value "value" ] ;
           fhir:ElementDefinition.slicing.discriminator.path [ fhir:value "url" ]
         ] ;
         fhir:ElementDefinition.slicing.ordered [ fhir:value "false"^^xsd:boolean ] ;
         fhir:ElementDefinition.slicing.rules [ fhir:value "open" ]
       ] ;
       fhir:ElementDefinition.short [ fhir:value "Extension" ] ;
       fhir:ElementDefinition.definition [ fhir:value "An Extension" ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]
     ], [
       fhir:index 345 ;
       fhir:Element.id [ fhir:value "Observation.component:repeat-number.extension:repeat-motif-order" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "repeat-motif-order" ] ;
       fhir:ElementDefinition.short [ fhir:value "Repeat Motif Order" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Use to group and order repeat expansion motifs." ] ;
       fhir:ElementDefinition.comment [ fhir:value "If there are multiple repeat expansion pairs, this must be used both to indicate the sequence position of a given repeat-motif and repeat-number pair and to group the related components together. Components with the same extension value describe the same motif." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "The value must be a natural number starting from 1 and increasing sequentially" ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ;
         fhir:ElementDefinition.type.profile [
           fhir:value "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/repeat-motif-order" ;
           fhir:index 0 ;
           fhir:link <http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/repeat-motif-order>
         ]
       ] ;
       fhir:ElementDefinition.condition [
         fhir:value "ele-1" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]
     ], [
       fhir:index 346 ;
       fhir:Element.id [ fhir:value "Observation.component:repeat-number.modifierExtension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ] ;
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ] ;
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ] ;
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension)." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "extensions" ;
         fhir:index 0
       ], [
         fhir:value "user content" ;
         fhir:index 1
       ], [
         fhir:value "modifiers" ;
         fhir:index 2
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ]
     ], [
       fhir:index 347 ;
       fhir:Element.id [ fhir:value "Observation.component:repeat-number.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "repeat-number" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ] ;
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           fhir:Coding.system [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs" ] ;
           fhir:Coding.code [ fhir:value "repeat-number" ]
         ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]
       ]
     ], [
       fhir:index 348 ;
       fhir:Element.id [ fhir:value "Observation.component:repeat-number.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "40" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](observation.html#notes) below." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Quantity" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]
       ]
     ], [
       fhir:index 349 ;
       fhir:Element.id [ fhir:value "Observation.component:repeat-number.dataAbsentReason" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ] ;
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "1" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.condition [
         fhir:value "obs-6" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]
       ]
     ], [
       fhir:index 350 ;
       fhir:Element.id [ fhir:value "Observation.component:repeat-number.interpretation" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ] ;
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ] ;
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ] ;
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag" ;
         fhir:index 0
       ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0 ;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ] ;
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]
         ] ;
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1" ;
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation|4.0.1>
         ]
       ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]
       ], [
         fhir:index 2 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]
       ], [
         fhir:index 3 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]
       ]
     ], [
       fhir:index 351 ;
       fhir:Element.id [ fhir:value "Observation.component:repeat-number.referenceRange" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ] ;
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ] ;
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ] ;
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
         fhir:ElementDefinition.base.max [ fhir:value "*" ]
       ] ;
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ] ;
       fhir:ElementDefinition.constraint [
         fhir:index 0 ;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ] ;
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ] ;
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ] ;
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ] ;
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ] ;
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element" ;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>
         ]
       ] ;
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ;
       fhir:ElementDefinition.mapping [
         fhir:index 0 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ] ;
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]
       ]
     ]
  ] ;
  fhir:StructureDefinition.differential [
     fhir:StructureDefinition.differential.element [
       fhir:index 0 ;
       fhir:Element.id [ fhir:value "Observation" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation" ] ;
       fhir:ElementDefinition.short [ fhir:value "Variant" ]
     ], [
       fhir:index 1 ;
       fhir:Element.id [ fhir:value "Observation.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "69548-6" ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           a loinc:69548-6 ;
           fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
           fhir:Coding.code [ fhir:value "69548-6" ]
         ]
       ]
     ], [
       fhir:index 2 ;
       fhir:Element.id [ fhir:value "Observation.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.value[x]" ] ;
       fhir:ElementDefinition.slicing [
         fhir:ElementDefinition.slicing.discriminator [
           fhir:index 0 ;
           fhir:ElementDefinition.slicing.discriminator.type [ fhir:value "type" ] ;
           fhir:ElementDefinition.slicing.discriminator.path [ fhir:value "$this" ]
         ] ;
         fhir:ElementDefinition.slicing.ordered [ fhir:value "false"^^xsd:boolean ] ;
         fhir:ElementDefinition.slicing.rules [ fhir:value "open" ]
       ]
     ], [
       fhir:index 3 ;
       fhir:Element.id [ fhir:value "Observation.value[x]:valueCodeableConcept" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.value[x]" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "valueCodeableConcept" ] ;
       fhir:ElementDefinition.short [ fhir:value "Indeterminate | No call | Present | Absent." ] ;
       fhir:ElementDefinition.definition [ fhir:value "The presence or absence of the variant described in the components. If not searching for specific variations and merely reporting what's found, the profile's value should be set to 'Present'." ] ;
       fhir:ElementDefinition.comment [ fhir:value "See [here](sequencing.html#variant-assessment) for usage guidance." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "required" ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://loinc.org/vs/LL1971-2" ;
           fhir:link <http://loinc.org/vs/LL1971-2>
         ]
       ]
     ], [
       fhir:index 4 ;
       fhir:Element.id [ fhir:value "Observation.method" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.method" ] ;
       fhir:ElementDefinition.short [ fhir:value "Sequencing | SNP array | PCR | Computational analysis | ..." ] ;
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://loinc.org/vs/LL4048-6" ;
           fhir:link <http://loinc.org/vs/LL4048-6>
         ]
       ]
     ], [
       fhir:index 5 ;
       fhir:Element.id [ fhir:value "Observation.component:representative-coding-hgvs" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "representative-coding-hgvs" ] ;
       fhir:ElementDefinition.short [ fhir:value "DNA change (c.HGVS)" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Human Genome Variation Society (HGVS) nomenclature for a single DNA marker. The use of the nomenclature must be extended to describe non-variations (aka. wild types) see samples for wild type examples." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ]
     ], [
       fhir:index 6 ;
       fhir:Element.id [ fhir:value "Observation.component:representative-coding-hgvs.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "48004-6" ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           a loinc:48004-6 ;
           fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
           fhir:Coding.code [ fhir:value "48004-6" ]
         ]
       ]
     ], [
       fhir:index 7 ;
       fhir:Element.id [ fhir:value "Observation.component:representative-coding-hgvs.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "A valid HGVS-formatted 'c.' string, e.g. NM_005228.5:c.2369C>T." ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "required" ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs" ;
           fhir:link <http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs>
         ]
       ]
     ], [
       fhir:index 8 ;
       fhir:Element.id [ fhir:value "Observation.component:genomic-hgvs" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "genomic-hgvs" ] ;
       fhir:ElementDefinition.short [ fhir:value "Genomic (gDNA) Change - gHGVS" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Description of the genomic (gDNA) sequence change using a valid HGVS-formatted string." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ]
     ], [
       fhir:index 9 ;
       fhir:Element.id [ fhir:value "Observation.component:genomic-hgvs.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "81290-9" ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           a loinc:81290-9 ;
           fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
           fhir:Coding.code [ fhir:value "81290-9" ]
         ]
       ]
     ], [
       fhir:index 10 ;
       fhir:Element.id [ fhir:value "Observation.component:genomic-hgvs.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "A valid HGVS-formatted 'g.' string, e.g. NC_000016.9:g.2124200_2138612dup" ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "required" ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs" ;
           fhir:link <http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs>
         ]
       ]
     ], [
       fhir:index 11 ;
       fhir:Element.id [ fhir:value "Observation.component:cytogenomic-nomenclature" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "cytogenomic-nomenclature" ] ;
       fhir:ElementDefinition.short [ fhir:value "Cytogenomic Nomenclature (ISCN)" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Fully describes a variant with a single code. Typically a large variant such as a mosaic, abnormal chromosome numbers, etc." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ]
     ], [
       fhir:index 12 ;
       fhir:Element.id [ fhir:value "Observation.component:cytogenomic-nomenclature.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "81291-7" ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           a loinc:81291-7 ;
           fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
           fhir:Coding.code [ fhir:value "81291-7" ]
         ]
       ]
     ], [
       fhir:index 13 ;
       fhir:Element.id [ fhir:value "Observation.component:cytogenomic-nomenclature.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Binding not yet defined" ]
       ]
     ], [
       fhir:index 14 ;
       fhir:Element.id [ fhir:value "Observation.component:genomic-ref-seq" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "genomic-ref-seq" ] ;
       fhir:ElementDefinition.short [ fhir:value "Genomic Reference Sequence" ] ;
       fhir:ElementDefinition.definition [ fhir:value "ID of the genomic reference sequence, which includes transcribed and non transcribed stretches" ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ]
     ], [
       fhir:index 15 ;
       fhir:Element.id [ fhir:value "Observation.component:genomic-ref-seq.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "48013-7" ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           a loinc:48013-7 ;
           fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
           fhir:Coding.code [ fhir:value "48013-7" ]
         ]
       ]
     ], [
       fhir:index 16 ;
       fhir:Element.id [ fhir:value "Observation.component:genomic-ref-seq.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "Versioned genomic reference sequence identifier" ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Multiple bindings acceptable (NCBI or LRG)" ]
       ]
     ], [
       fhir:index 17 ;
       fhir:Element.id [ fhir:value "Observation.component:representative-protein-ref-seq" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "representative-protein-ref-seq" ] ;
       fhir:ElementDefinition.short [ fhir:value "Protein Reference Sequence" ] ;
       fhir:ElementDefinition.definition [ fhir:value "ID of the protein reference sequence, which includes transcribed and non transcribed stretches. It covers the entire protein described." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ]
     ], [
       fhir:index 18 ;
       fhir:Element.id [ fhir:value "Observation.component:representative-protein-ref-seq.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "protein-ref-seq" ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           fhir:Coding.system [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs" ] ;
           fhir:Coding.code [ fhir:value "protein-ref-seq" ]
         ]
       ]
     ], [
       fhir:index 19 ;
       fhir:Element.id [ fhir:value "Observation.component:representative-protein-ref-seq.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "Versioned protein reference sequence identifier" ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Multiple bindings acceptable (NCBI or LRG)" ]
       ]
     ], [
       fhir:index 20 ;
       fhir:Element.id [ fhir:value "Observation.component:representative-transcript-ref-seq" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "representative-transcript-ref-seq" ] ;
       fhir:ElementDefinition.short [ fhir:value "Reference Transcript" ] ;
       fhir:ElementDefinition.definition [ fhir:value "NCBI's RefSeq ('NM_...'), Ensembl ('ENST...'), and LRG ('LRG...' plus 't1' to indicate transcript)" ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ]
     ], [
       fhir:index 21 ;
       fhir:Element.id [ fhir:value "Observation.component:representative-transcript-ref-seq.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "51958-7" ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           a loinc:51958-7 ;
           fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
           fhir:Coding.code [ fhir:value "51958-7" ]
         ]
       ]
     ], [
       fhir:index 22 ;
       fhir:Element.id [ fhir:value "Observation.component:representative-transcript-ref-seq.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "Versioned transcript reference sequence identifier" ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Multiple bindings acceptable (NCBI or LRG)" ]
       ]
     ], [
       fhir:index 23 ;
       fhir:Element.id [ fhir:value "Observation.component:exact-start-end" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "exact-start-end" ] ;
       fhir:ElementDefinition.short [ fhir:value "Exact Start-End" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The exact integer-based genomic coordinates of the start and end of the variant region." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ]
     ], [
       fhir:index 24 ;
       fhir:Element.id [ fhir:value "Observation.component:exact-start-end.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "81254-5" ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           a loinc:81254-5 ;
           fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
           fhir:Coding.code [ fhir:value "81254-5" ]
         ]
       ]
     ], [
       fhir:index 25 ;
       fhir:Element.id [ fhir:value "Observation.component:exact-start-end.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "Range in question. 'High' can be omitted for single nucleotide variants." ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Range" ]
       ]
     ], [
       fhir:index 26 ;
       fhir:Element.id [ fhir:value "Observation.component:inner-start-end" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "inner-start-end" ] ;
       fhir:ElementDefinition.short [ fhir:value "Inner Start-End" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The genomic coordinates of the narrowest genomic range in which the variant might reside. Used when the exact boundaries of the variant are not clear." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ]
     ], [
       fhir:index 27 ;
       fhir:Element.id [ fhir:value "Observation.component:inner-start-end.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "81302-2" ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           a loinc:81302-2 ;
           fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
           fhir:Coding.code [ fhir:value "81302-2" ]
         ]
       ]
     ], [
       fhir:index 28 ;
       fhir:Element.id [ fhir:value "Observation.component:inner-start-end.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "Imprecise variant inner-bounding range" ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Range" ]
       ]
     ], [
       fhir:index 29 ;
       fhir:Element.id [ fhir:value "Observation.component:outer-start-end" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "outer-start-end" ] ;
       fhir:ElementDefinition.short [ fhir:value "Outer Start-End" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The genomic coordinates of the widest genomic range in which the variant might reside. Used when the exact boundaries of the variant are not clear." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ]
     ], [
       fhir:index 30 ;
       fhir:Element.id [ fhir:value "Observation.component:outer-start-end.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "81301-4" ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           a loinc:81301-4 ;
           fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
           fhir:Coding.code [ fhir:value "81301-4" ]
         ]
       ]
     ], [
       fhir:index 31 ;
       fhir:Element.id [ fhir:value "Observation.component:outer-start-end.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "Imprecise variant outer-bounding range" ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Range" ]
       ]
     ], [
       fhir:index 32 ;
       fhir:Element.id [ fhir:value "Observation.component:coordinate-system" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "coordinate-system" ] ;
       fhir:ElementDefinition.short [ fhir:value "Coordinate System" ] ;
       fhir:ElementDefinition.definition [ fhir:value "These are different ways of identifying nucleotides or amino acids within a sequence. In the 1-based system, the first unit of the polymer (e.g. the first nucleotide) is counted as number 1. In the 0-based system, the number 0 designates the location before the first nucleotide. Different databases and file types may use different systems." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ]
     ], [
       fhir:index 33 ;
       fhir:Element.id [ fhir:value "Observation.component:coordinate-system.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "92822-6" ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           a loinc:92822-6 ;
           fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
           fhir:Coding.code [ fhir:value "92822-6" ]
         ]
       ]
     ], [
       fhir:index 34 ;
       fhir:Element.id [ fhir:value "Observation.component:coordinate-system.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "0-based interval counting | 0-based character counting | 1-based character counting" ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://loinc.org/vs/LL5323-2" ;
           fhir:link <http://loinc.org/vs/LL5323-2>
         ]
       ]
     ], [
       fhir:index 35 ;
       fhir:Element.id [ fhir:value "Observation.component:ref-allele" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "ref-allele" ] ;
       fhir:ElementDefinition.short [ fhir:value "Genomic Ref Allele" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Reference values ('normal') examined within the Reference Sequence." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ]
     ], [
       fhir:index 36 ;
       fhir:Element.id [ fhir:value "Observation.component:ref-allele.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "69547-8" ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           a loinc:69547-8 ;
           fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
           fhir:Coding.code [ fhir:value "69547-8" ]
         ]
       ]
     ], [
       fhir:index 37 ;
       fhir:Element.id [ fhir:value "Observation.component:ref-allele.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "Normalized string per the VCF format." ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "string" ]
       ]
     ], [
       fhir:index 38 ;
       fhir:Element.id [ fhir:value "Observation.component:alt-allele" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "alt-allele" ] ;
       fhir:ElementDefinition.short [ fhir:value "Genomic Alt Allele" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The genomic alternate allele is the contiguous segment of DNA in the test sample that differs from the reference allele at the same location and thus defines a variant." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ]
     ], [
       fhir:index 39 ;
       fhir:Element.id [ fhir:value "Observation.component:alt-allele.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "69551-0" ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           a loinc:69551-0 ;
           fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
           fhir:Coding.code [ fhir:value "69551-0" ]
         ]
       ]
     ], [
       fhir:index 40 ;
       fhir:Element.id [ fhir:value "Observation.component:alt-allele.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "Normalized string per the VCF format." ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "string" ]
       ]
     ], [
       fhir:index 41 ;
       fhir:Element.id [ fhir:value "Observation.component:coding-change-type" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "coding-change-type" ] ;
       fhir:ElementDefinition.short [ fhir:value "Coding DNA Change Type" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Type of DNA change observed. Convenience property for variants with exact breakpoints, required otherwise." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ]
     ], [
       fhir:index 42 ;
       fhir:Element.id [ fhir:value "Observation.component:coding-change-type.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "48019-4" ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           a loinc:48019-4 ;
           fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
           fhir:Coding.code [ fhir:value "48019-4" ]
         ]
       ]
     ], [
       fhir:index 43 ;
       fhir:Element.id [ fhir:value "Observation.component:coding-change-type.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "deletion | insertion | delins | SNV | copy_number_gain | copy_number_loss | ... (many)" ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Concepts in sequence ontology under SO:0002072" ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs" ;
           fhir:link <http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs>
         ]
       ]
     ], [
       fhir:index 44 ;
       fhir:Element.id [ fhir:value "Observation.component:genomic-source-class" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "genomic-source-class" ] ;
       fhir:ElementDefinition.short [ fhir:value "Genomic Source Class" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The genomic class of the specimen being analyzed: Germline for inherited genome, somatic for cancer genome, and prenatal for fetal genome." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ]
     ], [
       fhir:index 45 ;
       fhir:Element.id [ fhir:value "Observation.component:genomic-source-class.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "48002-0" ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           a loinc:48002-0 ;
           fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
           fhir:Coding.code [ fhir:value "48002-0" ]
         ]
       ]
     ], [
       fhir:index 46 ;
       fhir:Element.id [ fhir:value "Observation.component:genomic-source-class.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "Germline | Somatic | Fetal | Likely germline | Likely somatic | Likely fetal | Unknown genomic origin | De novo" ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://loinc.org/vs/LL378-1" ;
           fhir:link <http://loinc.org/vs/LL378-1>
         ]
       ]
     ], [
       fhir:index 47 ;
       fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "sample-allelic-frequency" ] ;
       fhir:ElementDefinition.short [ fhir:value "Sample Allelic Frequency" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The relative frequency of the allele at a given locus in the sample." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ]
     ], [
       fhir:index 48 ;
       fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "81258-6" ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           a loinc:81258-6 ;
           fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
           fhir:Coding.code [ fhir:value "81258-6" ]
         ]
       ]
     ], [
       fhir:index 49 ;
       fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "Relative frequency in the sample" ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Quantity" ]
       ]
     ], [
       fhir:index 50 ;
       fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.value[x].system" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x].system" ] ;
       fhir:ElementDefinition.patternUri [ fhir:value "http://unitsofmeasure.org" ]
     ], [
       fhir:index 51 ;
       fhir:Element.id [ fhir:value "Observation.component:allelic-read-depth" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "allelic-read-depth" ] ;
       fhir:ElementDefinition.short [ fhir:value "Allelic Read Depth" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Specifies the number of reads that identified the allele in question whether it consists of one or a small sequence of contiguous nucleotides. Different methods and purposes require different numbers of reads to be acceptable. Often >400, sometimes as few as 2-4." ] ;
       fhir:ElementDefinition.comment [ fhir:value "See [here](sequencing.html#variant-assessment) for usage guidance." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ]
     ], [
       fhir:index 52 ;
       fhir:Element.id [ fhir:value "Observation.component:allelic-read-depth.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "82121-5" ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           a loinc:82121-5 ;
           fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
           fhir:Coding.code [ fhir:value "82121-5" ]
         ]
       ]
     ], [
       fhir:index 53 ;
       fhir:Element.id [ fhir:value "Observation.component:allelic-read-depth.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "Unfiltered count of supporting reads" ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Quantity" ]
       ]
     ], [
       fhir:index 54 ;
       fhir:Element.id [ fhir:value "Observation.component:allelic-state" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "allelic-state" ] ;
       fhir:ElementDefinition.short [ fhir:value "Allelic State" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The observed level of occurrence of the variant in the set of chromosomes." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ]
     ], [
       fhir:index 55 ;
       fhir:Element.id [ fhir:value "Observation.component:allelic-state.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "53034-5" ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           a loinc:53034-5 ;
           fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
           fhir:Coding.code [ fhir:value "53034-5" ]
         ]
       ]
     ], [
       fhir:index 56 ;
       fhir:Element.id [ fhir:value "Observation.component:allelic-state.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "Heteroplasmic | Homoplasmic | Homozygous | Heterozygous | Hemizygous" ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://loinc.org/vs/LL381-5" ;
           fhir:link <http://loinc.org/vs/LL381-5>
         ]
       ]
     ], [
       fhir:index 57 ;
       fhir:Element.id [ fhir:value "Observation.component:variant-inheritance" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "variant-inheritance" ] ;
       fhir:ElementDefinition.short [ fhir:value "Origin of germline genetic variant" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The source or inheritance of a specific germline variation found in an individual patient." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ]
     ], [
       fhir:index 58 ;
       fhir:Element.id [ fhir:value "Observation.component:variant-inheritance.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "94186-4" ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           a loinc:94186-4 ;
           fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
           fhir:Coding.code [ fhir:value "94186-4" ]
         ]
       ]
     ], [
       fhir:index 59 ;
       fhir:Element.id [ fhir:value "Observation.component:variant-inheritance.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "Maternal | Paternal | Unknown" ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://loinc.org/vs/LL5489-1" ;
           fhir:link <http://loinc.org/vs/LL5489-1>
         ]
       ]
     ], [
       fhir:index 60 ;
       fhir:Element.id [ fhir:value "Observation.component:variant-inheritance-basis" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "variant-inheritance-basis" ] ;
       fhir:ElementDefinition.short [ fhir:value "Evidential basis for variant inheritance" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The method by which the variant inheritance is determined." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ]
     ], [
       fhir:index 61 ;
       fhir:Element.id [ fhir:value "Observation.component:variant-inheritance-basis.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "Basis for allelic phase" ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           a loinc:82309-6 ;
           fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
           fhir:Coding.code [ fhir:value "82309-6" ]
         ]
       ]
     ], [
       fhir:index 62 ;
       fhir:Element.id [ fhir:value "Observation.component:variant-inheritance-basis.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "Directly measured | Family DNA | Family history | Inferred from population data" ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://loinc.org/vs/LL4050-2" ;
           fhir:link <http://loinc.org/vs/LL4050-2>
         ]
       ]
     ], [
       fhir:index 63 ;
       fhir:Element.id [ fhir:value "Observation.component:variation-code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "variation-code" ] ;
       fhir:ElementDefinition.short [ fhir:value "Variation Code" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Accession number in a variant database such as ClinVar, given for cross-reference." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ]
     ], [
       fhir:index 64 ;
       fhir:Element.id [ fhir:value "Observation.component:variation-code.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "81252-9" ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           a loinc:81252-9 ;
           fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
           fhir:Coding.code [ fhir:value "81252-9" ]
         ]
       ]
     ], [
       fhir:index 65 ;
       fhir:Element.id [ fhir:value "Observation.component:variation-code.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "ClinVar ID or similar" ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ] ;
         fhir:ElementDefinition.binding.description [ fhir:value "Multiple bindings acceptable" ]
       ]
     ], [
       fhir:index 66 ;
       fhir:Element.id [ fhir:value "Observation.component:representative-protein-hgvs" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "representative-protein-hgvs" ] ;
       fhir:ElementDefinition.short [ fhir:value "Protein (Amino Acid) Change - pHGVS" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Description of the protein (amino acid) sequence change using a valid HGVS-formatted string. The description of the variant is surrounded in parentheses if it is calculated rather than directly observed." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ]
     ], [
       fhir:index 67 ;
       fhir:Element.id [ fhir:value "Observation.component:representative-protein-hgvs.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "48005-3" ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           a loinc:48005-3 ;
           fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
           fhir:Coding.code [ fhir:value "48005-3" ]
         ]
       ]
     ], [
       fhir:index 68 ;
       fhir:Element.id [ fhir:value "Observation.component:representative-protein-hgvs.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "A valid HGVS-formatted 'p.' string, e.g. NP_000050.2:p.(Asn1836Lys)" ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "required" ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs" ;
           fhir:link <http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs>
         ]
       ]
     ], [
       fhir:index 69 ;
       fhir:Element.id [ fhir:value "Observation.component:copy-number" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "copy-number" ] ;
       fhir:ElementDefinition.short [ fhir:value "Genomic Structural Variant Copy Number" ] ;
       fhir:ElementDefinition.definition [ fhir:value "The copy number of the large variant. In HGVS, this is the numeric value following the “X”. It is a unit-less value. If the value determined by the assay is not a whole number, a range or decimal number can be specified. Note that a copy number of 1 can imply a deletion." ] ;
       fhir:ElementDefinition.comment [ fhir:value "Copy number variants are often described with a single copy number value. However, due to the nature of assays, such as qPCR and microarray, it can be difficult to assign an exact copy number. Therefore, labs sometimes report a range instead of an exact copy number. They may alternatively choose to report decimal numbers, even if whole numbers are biologically correct.\n\nIn general, it can be difficult to estimate a copy number from measurements taken on a heterogenous population of cells, such as a tumor. As indicated in the ISCN 2020 specifications, it is appropriate to express the measurements using a range. Furthermore, regardless of cell population, many assays use fluorescent probes to detect copy number. These testing methodologies do not always provide an exact, discrete value for this data point." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "There SHALL be a code with a value of '1' if there is a value. If system is present, it SHALL be UCUM." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ]
     ], [
       fhir:index 70 ;
       fhir:Element.id [ fhir:value "Observation.component:copy-number.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "82155-3" ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           a loinc:82155-3 ;
           fhir:Coding.system [ fhir:value "http://loinc.org" ] ;
           fhir:Coding.code [ fhir:value "82155-3" ]
         ]
       ]
     ], [
       fhir:index 71 ;
       fhir:Element.id [ fhir:value "Observation.component:copy-number.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Quantity" ]
       ], [
         fhir:index 1 ;
         fhir:ElementDefinition.type.code [ fhir:value "Range" ]
       ]
     ], [
       fhir:index 72 ;
       fhir:Element.id [ fhir:value "Observation.component:variant-confidence-status" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "variant-confidence-status" ] ;
       fhir:ElementDefinition.short [ fhir:value "Variant Confidence Status" ] ;
       fhir:ElementDefinition.definition [ fhir:value "A code that represents the confidence of a true positive variant call." ] ;
       fhir:ElementDefinition.comment [ fhir:value "See [here](sequencing.html#variant-assessment) for usage guidance." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ]
     ], [
       fhir:index 73 ;
       fhir:Element.id [ fhir:value "Observation.component:variant-confidence-status.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "variant-confidence-status" ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           fhir:Coding.system [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs" ] ;
           fhir:Coding.code [ fhir:value "variant-confidence-status" ]
         ]
       ]
     ], [
       fhir:index 74 ;
       fhir:Element.id [ fhir:value "Observation.component:variant-confidence-status.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "High | Intermediate | Low" ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]
       ] ;
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "required" ] ;
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/uv/genomics-reporting/ValueSet/variant-confidence-status-vs" ;
           fhir:link <http://hl7.org/fhir/uv/genomics-reporting/ValueSet/variant-confidence-status-vs>
         ]
       ]
     ], [
       fhir:index 75 ;
       fhir:Element.id [ fhir:value "Observation.component:repeat-motif" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "repeat-motif" ] ;
       fhir:ElementDefinition.short [ fhir:value "Repeat Motif" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Nucleotides of a repeat expansion motif." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ]
     ], [
       fhir:index 76 ;
       fhir:Element.id [ fhir:value "Observation.component:repeat-motif.extension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ] ;
       fhir:ElementDefinition.slicing [
         fhir:ElementDefinition.slicing.discriminator [
           fhir:index 0 ;
           fhir:ElementDefinition.slicing.discriminator.type [ fhir:value "value" ] ;
           fhir:ElementDefinition.slicing.discriminator.path [ fhir:value "url" ]
         ] ;
         fhir:ElementDefinition.slicing.ordered [ fhir:value "false"^^xsd:boolean ] ;
         fhir:ElementDefinition.slicing.rules [ fhir:value "open" ]
       ]
     ], [
       fhir:index 77 ;
       fhir:Element.id [ fhir:value "Observation.component:repeat-motif.extension:repeat-motif-order" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "repeat-motif-order" ] ;
       fhir:ElementDefinition.comment [ fhir:value "If there are multiple repeat expansion pairs, this must be used both to indicate the sequence position of a given repeat-motif and repeat-number pair and to group the related components together. Components with the same extension value describe the same motif." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "The value must be a natural number starting from 1 and increasing sequentially" ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ;
         fhir:ElementDefinition.type.profile [
           fhir:value "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/repeat-motif-order" ;
           fhir:index 0 ;
           fhir:link <http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/repeat-motif-order>
         ]
       ]
     ], [
       fhir:index 78 ;
       fhir:Element.id [ fhir:value "Observation.component:repeat-motif.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "repeat-motif" ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           fhir:Coding.system [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs" ] ;
           fhir:Coding.code [ fhir:value "repeat-motif" ]
         ]
       ]
     ], [
       fhir:index 79 ;
       fhir:Element.id [ fhir:value "Observation.component:repeat-motif.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "CAG" ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "string" ]
       ]
     ], [
       fhir:index 80 ;
       fhir:Element.id [ fhir:value "Observation.component:repeat-number" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "repeat-number" ] ;
       fhir:ElementDefinition.short [ fhir:value "Repeat Number" ] ;
       fhir:ElementDefinition.definition [ fhir:value "Number of repeats of a repeat expansion." ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "*" ]
     ], [
       fhir:index 81 ;
       fhir:Element.id [ fhir:value "Observation.component:repeat-number.extension" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ] ;
       fhir:ElementDefinition.slicing [
         fhir:ElementDefinition.slicing.discriminator [
           fhir:index 0 ;
           fhir:ElementDefinition.slicing.discriminator.type [ fhir:value "value" ] ;
           fhir:ElementDefinition.slicing.discriminator.path [ fhir:value "url" ]
         ] ;
         fhir:ElementDefinition.slicing.ordered [ fhir:value "false"^^xsd:boolean ] ;
         fhir:ElementDefinition.slicing.rules [ fhir:value "open" ]
       ]
     ], [
       fhir:index 82 ;
       fhir:Element.id [ fhir:value "Observation.component:repeat-number.extension:repeat-motif-order" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ] ;
       fhir:ElementDefinition.sliceName [ fhir:value "repeat-motif-order" ] ;
       fhir:ElementDefinition.comment [ fhir:value "If there are multiple repeat expansion pairs, this must be used both to indicate the sequence position of a given repeat-motif and repeat-number pair and to group the related components together. Components with the same extension value describe the same motif." ] ;
       fhir:ElementDefinition.requirements [ fhir:value "The value must be a natural number starting from 1 and increasing sequentially" ] ;
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.max [ fhir:value "1" ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ;
         fhir:ElementDefinition.type.profile [
           fhir:value "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/repeat-motif-order" ;
           fhir:index 0 ;
           fhir:link <http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/repeat-motif-order>
         ]
       ]
     ], [
       fhir:index 83 ;
       fhir:Element.id [ fhir:value "Observation.component:repeat-number.code" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ] ;
       fhir:ElementDefinition.short [ fhir:value "repeat-number" ] ;
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0 ;
           fhir:Coding.system [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs" ] ;
           fhir:Coding.code [ fhir:value "repeat-number" ]
         ]
       ]
     ], [
       fhir:index 84 ;
       fhir:Element.id [ fhir:value "Observation.component:repeat-number.value[x]" ] ;
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ] ;
       fhir:ElementDefinition.short [ fhir:value "40" ] ;
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ] ;
       fhir:ElementDefinition.type [
         fhir:index 0 ;
         fhir:ElementDefinition.type.code [ fhir:value "Quantity" ]
       ]
     ]
  ] .

# - ontology header ------------------------------------------------------------

<http://hl7.org/fhir/StructureDefinition/variant.ttl> a owl:Ontology ;
  owl:imports fhir:fhir.ttl ;
  owl:versionIRI <http://build.fhir.org/StructureDefinition/variant.ttl> .