Order Catalog Implementation Guide
1.0.0 - STU 1

Order Catalog Implementation Guide, published by HL7 International / Orders and Observations. This guide is not an authorized publication; it is the continuous build for version 1.0.0 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/fhir-order-catalog/ and changes regularly. See the Directory of published versions

## : Clarithromycin oral antibacterial - XML Representation

Page standards status: Informative

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    <MedicationKnowledge xmlns="http://hl7.org/fhir">
      <id value="example-drug-clarithromycin-25mg-granule-suspension"/>
      <meta>
        <profile
                 value="http://hl7.org/fhir/uv/order-catalog/StructureDefinition/DrugKnowledge"/>
      </meta>
      <language value="en-US"/>
      <text>
        <status value="extensions"/>
        <div xmlns="http://www.w3.org/1999/xhtml" xml:lang="en-US" lang="en-US"><p class="res-header-id"><b>Generated Narrative: MedicationKnowledge example-drug-clarithromycin-25mg-granule-suspension</b></p><a name="example-drug-clarithromycin-25mg-granule-suspension"> </a><a name="hcexample-drug-clarithromycin-25mg-granule-suspension"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Language: en-US</p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-DrugKnowledge.html">item in a catalog of drugs</a></p></div><p><b>Reference to a catalog</b>: <a href="Composition-example-medication-catalog-header.html">Composition Drugs authorized for prescription in Healthyland</a></p><p><b>code</b>: <span title="Codes:{http://snomed.info/sct 769316002}">Clarithromycin 25 mg/mL oral suspension</span></p><p><b>intendedJurisdiction</b>: <span title="Codes:">Healthyland</span></p><p><b>name</b>: CLARITHROMYCINE GENERIC-LAB 25 mg/ml, granules for oral suspension</p><p><b>productType</b>: <span title="Codes:">Generic product</span></p><blockquote><p><b>indicationGuideline</b></p><h3>Indications</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Reference</b></td></tr><tr><td style="display: none">*</td><td><a href="ClinicalUseDefinition-example-bacterial-pharyngitis-indication.html">ClinicalUseDefinition: type = indication</a></td></tr><tr><td style="display: none">*</td><td><a href="ClinicalUseDefinition-example-acute-otitis-media-indication.html">ClinicalUseDefinition: type = indication</a></td></tr><tr><td style="display: none">*</td><td><a href="ClinicalUseDefinition-example-bacterial-sinusitis-indication.html">ClinicalUseDefinition: type = indication</a></td></tr></table><blockquote><p><b>dosingGuideline</b></p><h3>PatientCharacteristics</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://loinc.org 30525-0}">Age</span></td><td>0.5-12 years</td></tr></table></blockquote></blockquote><blockquote><p><b>medicineClassification</b></p><p><b>type</b>: <span title="Codes:">Anatomical Therapeutic Chemical (ATC)</span></p><p><b>source</b>: <a href="https://www.whocc.no/atc/structure_and_principles/">https://www.whocc.no/atc/structure_and_principles/</a></p><p><b>classification</b>: <span title="Codes:{http://www.whocc.no/atc J01FA09}">Clarithromycin</span></p></blockquote><blockquote><p><b>medicineClassification</b></p><p><b>type</b>: <span title="Codes:">SNOMED CT drug dispositions</span></p><p><b>source</b>: <a href="https://confluence.ihtsdotools.org/display/DOCEG/SNOMED+CT+Editorial+Guide+-+Pharmaceutical+and+Biologic+Product">https://confluence.ihtsdotools.org/display/DOCEG/SNOMED+CT+Editorial+Guide+-+Pharmaceutical+and+Biologic+Product</a></p><p><b>classification</b>: <span title="Codes:{http://snomed.info/sct 419241000}">Substance with antibacterial mechanism of action (substance)</span></p></blockquote><blockquote><p><b>packaging</b></p><h3>Costs</h3><table class="grid"><tr><td style="display: none">-</td><td><b>EffectiveDate</b></td><td><b>Type</b></td><td><b>Source</b></td><td><b>Cost[x]</b></td></tr><tr><td style="display: none">*</td><td>2021-02-01 --&gt; (ongoing)</td><td><span title="Codes:">public price</span></td><td>Healthyland Drug Administration</td><td><span title="Euro">€5.18</span> (EUR)</td></tr><tr><td style="display: none">*</td><td>2020-09-30 --&gt; 2021-01-31</td><td><span title="Codes:">public price</span></td><td>Healthyland Drug Administration</td><td><span title="Euro">€5.20</span> (EUR)</td></tr><tr><td style="display: none">*</td><td>2010-03-01 --&gt; (ongoing)</td><td><span title="Codes:">manufacturers' cost</span></td><td>Healthyland Drug Administration</td><td><span title="Euro">€4.40</span> (EUR)</td></tr></table><p><b>packagedProduct</b>: <a href="PackagedProductDefinition-example-drug-package-clarithromycin.html">PackagedProductDefinition Package for CLARITHROMYCINE GENERIC-LAB 25 mg/ml, granules for oral suspension in 100 ml HDPE bottle</a></p></blockquote><p><b>clinicalUseIssue</b>: <a href="ClinicalUseDefinition-example-allergy-contraindication.html">ClinicalUseDefinition: type = contraindication</a></p><blockquote><p><b>definitional</b></p><p><b>doseForm</b>: <span title="Codes:{http://snomed.info/sct 385029002}, {http://standardterms.edqm.eu 10113000}">Granules for oral suspension</span></p><p><b>intendedRoute</b>: <span title="Codes:{http://snomed.info/sct 26643006}">Oral route</span></p><blockquote><p><b>ingredient</b></p><h3>Items</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Concept</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 387487009}">Clarithromycin</span></td></tr></table><p><b>type</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/v3-RoleClass ACTIB}">active ingredient - basis of strength</span></p><p><b>strength</b>: 25 milligram<span style="background: LightGoldenRodYellow"> (Details: UCUM  codemg = 'mg')</span>/1 milliliter<span style="background: LightGoldenRodYellow"> (Details: UCUM  codemL = 'mL')</span></p></blockquote><blockquote><p><b>ingredient</b></p><h3>Items</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Concept</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 11320009}">Sucrose</span></td></tr></table><p><b>type</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/v3-RoleClass IACT}">inactive ingredient</span></p></blockquote></blockquote></div>
      </text>
      <extension
                 url="http://hl7.org/fhir/uv/order-catalog/StructureDefinition/CatalogReference">
        <valueReference>🔗
          <reference value="Composition/example-medication-catalog-header"/>
        </valueReference>
      </extension>
      <code>
        <coding>
          <system value="http://snomed.info/sct"/>
          <code value="769316002"/>
          <display value="Clarithromycin 25 mg/mL oral suspension"/>
        </coding>
      </code>
      <intendedJurisdiction>
        <text value="Healthyland"/>
      </intendedJurisdiction>
      <name
            value="CLARITHROMYCINE GENERIC-LAB 25 mg/ml, granules for oral suspension"/>
      <productType>
        <text value="Generic product"/>
      </productType>
      <indicationGuideline>
        <indication>
          <reference>🔗
            <reference
                       value="ClinicalUseDefinition/example-bacterial-pharyngitis-indication"/>
          </reference>
        </indication>
        <indication>
          <reference>🔗
            <reference
                       value="ClinicalUseDefinition/example-acute-otitis-media-indication"/>
          </reference>
        </indication>
        <indication>
          <reference>🔗
            <reference
                       value="ClinicalUseDefinition/example-bacterial-sinusitis-indication"/>
          </reference>
        </indication>
        <dosingGuideline>
          <patientCharacteristic>
            <type>
              <coding>
                <system value="http://loinc.org"/>
                <code value="30525-0"/>
                <display value="Age"/>
              </coding>
            </type>
            <valueRange>
              <low>
                <value value="0.5"/>
                <unit value="years"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="a"/>
              </low>
              <high>
                <value value="12"/>
                <unit value="years"/>
                <system value="http://unitsofmeasure.org"/>
                <code value="a"/>
              </high>
            </valueRange>
          </patientCharacteristic>
        </dosingGuideline>
      </indicationGuideline>
      <medicineClassification>
        <type>
          <text value="Anatomical Therapeutic Chemical (ATC)"/>
        </type>
        <sourceUri value="https://www.whocc.no/atc/structure_and_principles/"/>
        <classification>
          <coding>
            <system value="http://www.whocc.no/atc"/>
            <code value="J01FA09"/>
            <display value="Clarithromycin"/>
          </coding>
        </classification>
      </medicineClassification>
      <medicineClassification>
        <type>
          <text value="SNOMED CT drug dispositions"/>
        </type>
        <sourceUri
                   value="https://confluence.ihtsdotools.org/display/DOCEG/SNOMED+CT+Editorial+Guide+-+Pharmaceutical+and+Biologic+Product"/>
        <classification>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="419241000"/>
            <display
                     value="Substance with antibacterial mechanism of action (substance)"/>
          </coding>
        </classification>
      </medicineClassification>
      <packaging>
        <cost>
          <effectiveDate>
            <start value="2021-02-01"/>
          </effectiveDate>
          <type>
            <text value="public price"/>
          </type>
          <source value="Healthyland Drug Administration"/>
          <costMoney>
            <value value="5.18"/>
            <currency value="EUR"/>
          </costMoney>
        </cost>
        <cost>
          <effectiveDate>
            <start value="2020-09-30"/>
            <end value="2021-01-31"/>
          </effectiveDate>
          <type>
            <text value="public price"/>
          </type>
          <source value="Healthyland Drug Administration"/>
          <costMoney>
            <value value="5.2"/>
            <currency value="EUR"/>
          </costMoney>
        </cost>
        <cost>
          <effectiveDate>
            <start value="2010-03-01"/>
          </effectiveDate>
          <type>
            <text value="manufacturers' cost"/>
          </type>
          <source value="Healthyland Drug Administration"/>
          <costMoney>
            <value value="4.4"/>
            <currency value="EUR"/>
          </costMoney>
        </cost>
        <packagedProduct>🔗
          <reference
                     value="PackagedProductDefinition/example-drug-package-clarithromycin"/>
        </packagedProduct>
      </packaging>
      <clinicalUseIssue>🔗
        <reference
                   value="ClinicalUseDefinition/example-allergy-contraindication"/>
      </clinicalUseIssue>
      <definitional>
        <doseForm>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="385029002"/>
            <display value="Granules for oral suspension"/>
          </coding>
          <coding>
            <system value="http://standardterms.edqm.eu"/>
            <code value="10113000"/>
            <display value="Granules for oral suspension"/>
          </coding>
        </doseForm>
        <intendedRoute>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="26643006"/>
            <display value="Oral route"/>
          </coding>
        </intendedRoute>
        <ingredient>
          <item>
            <concept>
              <coding>
                <system value="http://snomed.info/sct"/>
                <code value="387487009"/>
                <display value="Clarithromycin"/>
              </coding>
            </concept>
          </item>
          <type>
            <coding>
              <system value="http://terminology.hl7.org/CodeSystem/v3-RoleClass"/>
              <code value="ACTIB"/>
              <display value="active ingredient - basis of strength"/>
            </coding>
          </type>
          <strengthRatio>
            <numerator>
              <value value="25"/>
              <unit value="milligram"/>
              <system value="http://unitsofmeasure.org"/>
              <code value="mg"/>
            </numerator>
            <denominator>
              <value value="1"/>
              <unit value="milliliter"/>
              <system value="http://unitsofmeasure.org"/>
              <code value="mL"/>
            </denominator>
          </strengthRatio>
        </ingredient>
        <ingredient>
          <item>
            <concept>
              <coding>
                <system value="http://snomed.info/sct"/>
                <code value="11320009"/>
                <display value="Sucrose"/>
              </coding>
            </concept>
          </item>
          <type>
            <coding>
              <system value="http://terminology.hl7.org/CodeSystem/v3-RoleClass"/>
              <code value="IACT"/>
              <display value="inactive ingredient"/>
            </coding>
          </type>
        </ingredient>
      </definitional>
    </MedicationKnowledge>