minimal Common Oncology Data Elements (mCODE) Implementation Guide, published by HL7 International / Clinical Interoperability Council. This guide is not an authorized publication; it is the continuous build for version 4.0.0-ballot built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/fhir-mCODE-ig/ and changes regularly. See the Directory of published versions
<Observation xmlns="http://hl7.org/fhir">
<id value="gx-genomic-variant-somatic-mtap"/>
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<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p class="res-header-id"><b>Generated Narrative: Observation gx-genomic-variant-somatic-mtap</b></p><a name="gx-genomic-variant-somatic-mtap"> </a><a name="hcgx-genomic-variant-somatic-mtap"> </a><a name="gx-genomic-variant-somatic-mtap-en-US"> </a><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 69548-6}">Genetic variant assessment</span></p><p><b>subject</b>: <a href="Patient-gx-cancer-patient-adam-anyperson.html">Adam Anyperson Male, DoB: 1990-01-01 ( Medical Record Number: 123456789)</a></p><p><b>effective</b>: 2019-04-01</p><p><b>performer</b>: <a href="Practitioner-us-core-practitioner-owen-oncologist.html">Practitioner Owen Oncologist </a></p><p><b>value</b>: <span title="Codes:{http://loinc.org LA9633-4}">Present</span></p><p><b>method</b>: <span title="Codes:{http://loinc.org LA26398-0}">Sequencing</span></p><blockquote><p><b>component</b></p><p><b>code</b>: <span title="Codes:{http://loinc.org 48018-6}">Gene studied [ID]</span></p><p><b>value</b>: <span title="Codes:{http://www.genenames.org HGNC:7413}, {https://www.ncbi.nlm.nih.gov/gene 4507}">MTAP</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: <span title="Codes:{http://loinc.org 48002-0}">Genomic source class [Type]</span></p><p><b>value</b>: <span title="Codes:{http://loinc.org LA6684-0}">Somatic</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: <span title="Codes:{http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs molecular-consequence}">Molecular Consequence</span></p><p><b>value</b>: <span title="Codes:{http://www.sequenceontology.org/ SO:0001743}">copy_number_loss</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: <span title="Codes:{http://loinc.org 62374-4}">Human reference sequence assembly version</span></p><p><b>value</b>: <span title="Codes:{http://loinc.org LA14029-5}">GRCh37</span></p></blockquote></div>
</text>
<status value="final"/>
<category>
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<code value="laboratory"/>
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<code>
<coding>
<system value="http://loinc.org"/>
<code value="69548-6"/>
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</code>
<subject>🔗
<reference value="Patient/gx-cancer-patient-adam-anyperson"/>
</subject>
<effectiveDateTime value="2019-04-01"/>
<performer>🔗
<reference value="Practitioner/us-core-practitioner-owen-oncologist"/>
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<coding>
<system value="http://loinc.org"/>
<code value="LA9633-4"/>
<display value="Present"/>
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<code value="LA26398-0"/>
<display value="Sequencing"/>
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<code value="48018-6"/>
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</code>
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<coding>
<system value="http://www.genenames.org"/>
<code value="HGNC:7413"/>
<display value="MTAP"/>
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<coding>
<system value="https://www.ncbi.nlm.nih.gov/gene"/>
<code value="4507"/>
<display value="MTAP"/>
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<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="48002-0"/>
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<valueCodeableConcept>
<coding>
<system value="http://loinc.org"/>
<code value="LA6684-0"/>
<display value="Somatic"/>
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<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs"/>
<code value="molecular-consequence"/>
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<valueCodeableConcept>
<coding>
<system value="http://www.sequenceontology.org/"/>
<code value="SO:0001743"/>
<display value="copy_number_loss"/>
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<coding>
<system value="http://loinc.org"/>
<code value="62374-4"/>
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<coding>
<system value="http://loinc.org"/>
<code value="LA14029-5"/>
<display value="GRCh37"/>
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