Generated Narrative: Patient gx-cancer-patient-adam-anyperson Adam Anyperson Male, DoB: 1990-01-01 ( Medical Record Number: 123456789) Other Id: Patient external identifier/22ea1d1b-03a5-47d6-81e0-b9b4cbb15ccf (use: usual, ) Contact Detail 987 Main St Anytown 12345 US US Core Birth Sex Extension M
Generated Narrative: DiagnosticReport gx-genomics-report-adam-anyperson Genetic analysis report (Genetics) Subject Adam Anyperson Male, DoB: 1990-01-01 ( Medical Record Number: 123456789) When For 2022-02-15 19:28:58+0500 Performer Organization Gensop Labs, Inc. Report Details Code Value Flags When For Genetic variant assessment Present Final 2019-04-01 Genetic variant assessment Present Final 2019-04-01 Genetic variant assessment Present Final 2019-04-01 Genetic variant assessment Present Final 2019-04-01 Genetic variant assessment Present Final 2019-04-01 Genetic variant assessment Present Final 2019-04-01 Genetic variant assessment Present Final 2019-04-01 Genetic variant assessment Present Final 2019-04-01 Diagnostic Implication Final 2019-04-01 Diagnostic Implication Final 2019-04-01 Diagnostic Implication Final 2019-04-01 Genetic variant assessment Present Final 2019-04-01 Genetic variant assessment Absent Final 2019-04-01 Mutations/Megabase [# Ratio] in Tumor 57.1 1/1000000{Base} (Details: UCUM code1/1000000{Base} = '1/1000000{Base}') Final 2019-04-01 Microsatellite instability [Interpretation] in Cancer specimen Qualitative MSI-H Final 2019-04-01 Therapeutic Implication Final 2019-04-01 Therapeutic Implication Final 2019-04-01 Therapeutic Implication Final 2019-04-01 Therapeutic Implication Final 2019-04-01 Therapeutic Implication Final 2019-04-01
Generated Narrative: ServiceRequest gx-order-tumornormal-gensop-inc identifier: Filler Identifier/22howe status: Completed intent: Order code: xT - 648 gene panel subject: Adam Anyperson Male, DoB: 1990-01-01 ( Medical Record Number: 123456789) reasonCode: Malignant neoplasm of unspecified part of bronchus or lung
Malignant neoplasm of unspecified part of bronchus or lung
Generated Narrative: Practitioner gx-practitioner-test-pathologist name: Test Pathologist, MD
Generated Narrative: Specimen gx-genomic-specimen-tumornormal-tumor status: Available type: Tumor subject: Adam Anyperson Male, DoB: 1990-01-01 ( Medical Record Number: 123456789) receivedTime: 2021-02-09 21:30:50+0500 Collections - Collected[x] BodySite * 2021-02-06 17:15:00+0500 Left lung structure (body structure)
Generated Narrative: Specimen gx-genomic-specimen-tumornormal-normal status: Available type: Whole Blood subject: Adam Anyperson Male, DoB: 1990-01-01 ( Medical Record Number: 123456789) receivedTime: 2021-02-09 21:30:50+0500 Collections - Collected[x] * 2021-02-06 17:15:00+0500
Generated Narrative: Observation gx-genomic-variant-somatic-bap1-indel status: Final category: Laboratory code: Genetic variant assessment subject: Adam Anyperson Male, DoB: 1990-01-01 ( Medical Record Number: 123456789) effective: 2019-04-01 performer: Practitioner Owen Oncologist value: Present method: Sequencing component code: Gene studied [ID] value: BAP1 component code: Transcript reference sequence [ID] value: NM_004656.4 component code: DNA change (c.HGVS) value: T}">NM_004656.4:c.1768C>T component code: Amino acid change (pHGVS) value: NP_004647.1:p.(Gln590Ter) component code: Genomic source class [Type] value: Somatic component code: Sample variant allelic frequency [NFr] value: 57.4 % (Details: UCUM code% = '%') component code: Molecular Consequence value: stop_gained component code: Human reference sequence assembly version value: GRCh37
Generated Narrative: Observation gx-genomic-variant-somatic-cdkn2a-cnv status: Final category: Laboratory code: Genetic variant assessment subject: Adam Anyperson Male, DoB: 1990-01-01 ( Medical Record Number: 123456789) effective: 2019-04-01 performer: Practitioner Owen Oncologist value: Present method: Sequencing component code: Gene studied [ID] value: CDKN2A component code: Genomic source class [Type] value: Somatic component code: Molecular Consequence value: copy_number_loss component code: Human reference sequence assembly version value: GRCh37
Generated Narrative: Observation gx-genomic-variant-somatic-cdkn2b-cnv status: Final category: Laboratory code: Genetic variant assessment subject: Adam Anyperson Male, DoB: 1990-01-01 ( Medical Record Number: 123456789) effective: 2019-04-01 performer: Practitioner Owen Oncologist value: Present method: Sequencing component code: Gene studied [ID] value: CDKN2B component code: Genomic source class [Type] value: Somatic component code: Molecular Consequence value: copy_number_loss component code: Human reference sequence assembly version value: GRCh37
Generated Narrative: Observation gx-genomic-variant-somatic-kdm5d status: Final category: Laboratory code: Genetic variant assessment subject: Adam Anyperson Male, DoB: 1990-01-01 ( Medical Record Number: 123456789) effective: 2019-04-01 performer: Practitioner Owen Oncologist value: Present method: Sequencing component code: Gene studied [ID] value: KDM5D component code: Genomic source class [Type] value: Somatic component code: Molecular Consequence value: copy_number_loss component code: Human reference sequence assembly version value: GRCh37
Generated Narrative: Observation gx-genomic-variant-somatic-mtap status: Final category: Laboratory code: Genetic variant assessment subject: Adam Anyperson Male, DoB: 1990-01-01 ( Medical Record Number: 123456789) effective: 2019-04-01 performer: Practitioner Owen Oncologist value: Present method: Sequencing component code: Gene studied [ID] value: MTAP component code: Genomic source class [Type] value: Somatic component code: Molecular Consequence value: copy_number_loss component code: Human reference sequence assembly version value: GRCh37
Generated Narrative: Observation gx-genomic-variant-somatic-mycn status: Final category: Laboratory code: Genetic variant assessment subject: Adam Anyperson Male, DoB: 1990-01-01 ( Medical Record Number: 123456789) effective: 2019-04-01 performer: Practitioner Owen Oncologist value: Present method: Sequencing component code: Gene studied [ID] value: MYCN component code: Genomic source class [Type] value: Somatic component code: Molecular Consequence value: copy_number_gain component code: Human reference sequence assembly version value: GRCh37
Generated Narrative: Observation gx-genomic-variant-somatic-pof1b status: Final category: Laboratory code: Genetic variant assessment subject: Adam Anyperson Male, DoB: 1990-01-01 ( Medical Record Number: 123456789) effective: 2019-04-01 performer: Practitioner Owen Oncologist value: Present method: Sequencing component code: Gene studied [ID] value: POF1B component code: Genomic source class [Type] value: Somatic component code: Molecular Consequence value: missense_variant component code: Transcript reference sequence [ID] value: NM_004656 component code: DNA change (c.HGVS) value: T}">NM_001307940.2:c.430C>T component code: Amino acid change (pHGVS) value: NP_001294869.1:p.(Pro144Ser) component code: Sample variant allelic frequency [NFr] value: 78.6 % (Details: UCUM code% = '%') component code: Human reference sequence assembly version value: GRCh37
Generated Narrative: Observation gx-genomic-variant-somatic-polrmt status: Final category: Laboratory code: Genetic variant assessment subject: Adam Anyperson Male, DoB: 1990-01-01 ( Medical Record Number: 123456789) effective: 2019-04-01 performer: Practitioner Owen Oncologist value: Present method: Sequencing component code: Gene studied [ID] value: POLRMT component code: Genomic source class [Type] value: Somatic component code: Molecular Consequence value: missense_variant component code: Transcript reference sequence [ID] value: NM_005035 component code: DNA change (c.HGVS) value: A}">NM_005035.4:c.598G>A component code: Amino acid change (pHGVS) value: NP_005026.3:p.(Gly200Arg) component code: Sample variant allelic frequency [NFr] value: 75.6 % (Details: UCUM code% = '%') component code: Human reference sequence assembly version value: GRCh37
Generated Narrative: Observation gx-genomic-diagnostic-implication-bap1 status: Final category: Laboratory code: Diagnostic Implication subject: Adam Anyperson Male, DoB: 1990-01-01 ( Medical Record Number: 123456789) effective: 2019-04-01 performer: Practitioner Owen Oncologist derivedFrom: Observation Genetic variant assessment Components - Code Value[x] * Functional Effect loss of function variant
Generated Narrative: Observation gx-genomic-diagnostic-implication-pof1b status: Final category: Laboratory code: Diagnostic Implication subject: Adam Anyperson Male, DoB: 1990-01-01 ( Medical Record Number: 123456789) effective: 2019-04-01 performer: Practitioner Owen Oncologist derivedFrom: Observation Genetic variant assessment Components - Code Value[x] * Genetic variation clinical significance [Imp] Uncertain significance
Generated Narrative: Observation gx-genomic-diagnostic-implication-polrmt status: Final category: Laboratory code: Diagnostic Implication subject: Adam Anyperson Male, DoB: 1990-01-01 ( Medical Record Number: 123456789) effective: 2019-04-01 performer: Practitioner Owen Oncologist derivedFrom: Observation Genetic variant assessment Components - Code Value[x] * Genetic variation clinical significance [Imp] Uncertain significance
Generated Narrative: Observation gx-genomic-variant-fusion-met-alk status: Final category: Laboratory code: Genetic variant assessment subject: Adam Anyperson Male, DoB: 1990-01-01 ( Medical Record Number: 123456789) effective: 2019-04-01 performer: Practitioner Owen Oncologist value: Present method: Sequencing component code: Gene studied [ID] value: MET component code: Gene studied [ID] value: ALK component code: DNA change type value: complex chromosomal rearrangement component code: Genomic source class [Type] value: Somatic
Generated Narrative: Observation gx-genomic-variant-pertinent-negative-nras-kit-braf status: Final category: Laboratory code: Genetic variant assessment subject: Adam Anyperson Male, DoB: 1990-01-01 ( Medical Record Number: 123456789) effective: 2019-04-01 performer: Practitioner Owen Oncologist value: Absent method: Sequencing component code: Gene studied [ID] value: NRAS component code: Gene studied [ID] value: KIT component code: Gene studied [ID] value: BRAF
Generated Narrative: Observation gx-genomic-tmb status: Final category: Laboratory code: Mutations/Megabase [# Ratio] in Tumor subject: Adam Anyperson Male, DoB: 1990-01-01 ( Medical Record Number: 123456789) effective: 2019-04-01 performer: Practitioner Owen Oncologist value: 57.1 1/1000000{Base} (Details: UCUM code1/1000000{Base} = '1/1000000{Base}')
Generated Narrative: Observation gx-genomic-therapeutic-implication-alectinib status: Final category: Laboratory code: Therapeutic Implication subject: Adam Anyperson Male, DoB: 1990-01-01 ( Medical Record Number: 123456789) effective: 2019-04-01 performer: Practitioner Owen Oncologist derivedFrom: Observation Genetic variant assessment component code: Medication assessed [ID] value: alectinib component code: Predicted Therapeutic Implication value: Presumed responsive
Generated Narrative: Observation gx-genomic-therapeutic-implication-brigatinib status: Final category: Laboratory code: Therapeutic Implication subject: Adam Anyperson Male, DoB: 1990-01-01 ( Medical Record Number: 123456789) effective: 2019-04-01 performer: Practitioner Owen Oncologist derivedFrom: Observation Genetic variant assessment component code: Medication assessed [ID] value: brigatinib component code: Predicted Therapeutic Implication value: Presumed responsive
Generated Narrative: Observation gx-genomic-therapeutic-implication-ceritinib status: Final category: Laboratory code: Therapeutic Implication subject: Adam Anyperson Male, DoB: 1990-01-01 ( Medical Record Number: 123456789) effective: 2019-04-01 performer: Practitioner Owen Oncologist derivedFrom: Observation Genetic variant assessment component code: Medication assessed [ID] value: ceritinib component code: Predicted Therapeutic Implication value: Presumed responsive
Generated Narrative: Observation gx-genomic-therapeutic-implication-crizotinib status: Final category: Laboratory code: Therapeutic Implication subject: Adam Anyperson Male, DoB: 1990-01-01 ( Medical Record Number: 123456789) effective: 2019-04-01 performer: Practitioner Owen Oncologist derivedFrom: Observation Genetic variant assessment component code: Medication assessed [ID] value: crizotinib component code: Predicted Therapeutic Implication value: Presumed responsive
Generated Narrative: Observation gx-genomic-therapeutic-implication-lorlatinib status: Final category: Laboratory code: Therapeutic Implication subject: Adam Anyperson Male, DoB: 1990-01-01 ( Medical Record Number: 123456789) effective: 2019-04-01 performer: Practitioner Owen Oncologist derivedFrom: Observation Genetic variant assessment component code: Medication assessed [ID] value: lorlatinib component code: Predicted Therapeutic Implication value: Presumed responsive