@prefix fhir: <http://hl7.org/fhir/> .
@prefix loinc: <https://loinc.org/rdf/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

# - resource -------------------------------------------------------------------

<http://hl7.org/fhir/us/mcode/Observation/gx-genomic-variant-somatic-mtap> a fhir:Observation ;
  fhir:nodeRole fhir:treeRoot ;
  fhir:id [ fhir:v "gx-genomic-variant-somatic-mtap"] ; # 
  fhir:meta [
     fhir:profile ( [
       fhir:v "http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-genomic-variant"^^xsd:anyURI ;
       fhir:link <http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-genomic-variant>
     ] )
  ] ; # 
  fhir:text [
     fhir:status [ fhir:v "generated" ] ;
     fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: Observation gx-genomic-variant-somatic-mtap</b></p><a name=\"gx-genomic-variant-somatic-mtap\"> </a><a name=\"hcgx-genomic-variant-somatic-mtap\"> </a><a name=\"gx-genomic-variant-somatic-mtap-en-US\"> </a><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 69548-6}\">Genetic variant assessment</span></p><p><b>subject</b>: <a href=\"Patient-gx-cancer-patient-adam-anyperson.html\">Adam Anyperson  Male, DoB: 1990-01-01 ( Medical Record Number: 123456789)</a></p><p><b>effective</b>: 2019-04-01</p><p><b>performer</b>: <a href=\"Practitioner-us-core-practitioner-owen-oncologist.html\">Practitioner Owen Oncologist </a></p><p><b>value</b>: <span title=\"Codes:{http://loinc.org LA9633-4}\">Present</span></p><p><b>method</b>: <span title=\"Codes:{http://loinc.org LA26398-0}\">Sequencing</span></p><blockquote><p><b>component</b></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 48018-6}\">Gene studied [ID]</span></p><p><b>value</b>: <span title=\"Codes:{http://www.genenames.org HGNC:7413}, {https://www.ncbi.nlm.nih.gov/gene 4507}\">MTAP</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 48002-0}\">Genomic source class [Type]</span></p><p><b>value</b>: <span title=\"Codes:{http://loinc.org LA6684-0}\">Somatic</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: <span title=\"Codes:{http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs molecular-consequence}\">Molecular Consequence</span></p><p><b>value</b>: <span title=\"Codes:{http://www.sequenceontology.org/ SO:0001743}\">copy_number_loss</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 62374-4}\">Human reference sequence assembly version</span></p><p><b>value</b>: <span title=\"Codes:{http://loinc.org LA14029-5}\">GRCh37</span></p></blockquote></div>"^^rdf:XMLLiteral
  ] ; # 
  fhir:status [ fhir:v "final"] ; # 
  fhir:category ( [
     fhir:coding ( [
       fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/observation-category"^^xsd:anyURI ] ;
       fhir:code [ fhir:v "laboratory" ]
     ] )
  ] ) ; # 
  fhir:code [
     fhir:coding ( [
       a loinc:69548-6 ;
       fhir:system [ fhir:v "http://loinc.org"^^xsd:anyURI ] ;
       fhir:code [ fhir:v "69548-6" ]
     ] )
  ] ; # 
  fhir:subject [
     fhir:link <http://hl7.org/fhir/us/mcode/Patient/gx-cancer-patient-adam-anyperson> ;
     fhir:reference [ fhir:v "Patient/gx-cancer-patient-adam-anyperson" ]
  ] ; # 
  fhir:effective [
     a fhir:dateTime ;
     fhir:v "2019-04-01"^^xsd:date
  ] ; # 
  fhir:performer ( [
     fhir:link <http://hl7.org/fhir/us/mcode/Practitioner/us-core-practitioner-owen-oncologist> ;
     fhir:reference [ fhir:v "Practitioner/us-core-practitioner-owen-oncologist" ]
  ] ) ; # 
  fhir:value [
     a fhir:CodeableConcept ;
     fhir:coding ( [
       a loinc:LA9633-4 ;
       fhir:system [ fhir:v "http://loinc.org"^^xsd:anyURI ] ;
       fhir:code [ fhir:v "LA9633-4" ] ;
       fhir:display [ fhir:v "Present" ]
     ] )
  ] ; # 
  fhir:method [
     fhir:coding ( [
       a loinc:LA26398-0 ;
       fhir:system [ fhir:v "http://loinc.org"^^xsd:anyURI ] ;
       fhir:code [ fhir:v "LA26398-0" ] ;
       fhir:display [ fhir:v "Sequencing" ]
     ] )
  ] ; # 
  fhir:component ( [
     fhir:code [
       fhir:coding ( [
         a loinc:48018-6 ;
         fhir:system [ fhir:v "http://loinc.org"^^xsd:anyURI ] ;
         fhir:code [ fhir:v "48018-6" ]
       ] )
     ] ;
     fhir:value [
       a fhir:CodeableConcept ;
       fhir:coding ( [
         fhir:system [ fhir:v "http://www.genenames.org"^^xsd:anyURI ] ;
         fhir:code [ fhir:v "HGNC:7413" ] ;
         fhir:display [ fhir:v "MTAP" ]
       ] [
         fhir:system [ fhir:v "https://www.ncbi.nlm.nih.gov/gene"^^xsd:anyURI ] ;
         fhir:code [ fhir:v "4507" ] ;
         fhir:display [ fhir:v "MTAP" ]
       ] )
     ]
  ] [
     fhir:code [
       fhir:coding ( [
         a loinc:48002-0 ;
         fhir:system [ fhir:v "http://loinc.org"^^xsd:anyURI ] ;
         fhir:code [ fhir:v "48002-0" ]
       ] )
     ] ;
     fhir:value [
       a fhir:CodeableConcept ;
       fhir:coding ( [
         a loinc:LA6684-0 ;
         fhir:system [ fhir:v "http://loinc.org"^^xsd:anyURI ] ;
         fhir:code [ fhir:v "LA6684-0" ] ;
         fhir:display [ fhir:v "Somatic" ]
       ] )
     ]
  ] [
     fhir:code [
       fhir:coding ( [
         fhir:system [ fhir:v "http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs"^^xsd:anyURI ] ;
         fhir:code [ fhir:v "molecular-consequence" ]
       ] )
     ] ;
     fhir:value [
       a fhir:CodeableConcept ;
       fhir:coding ( [
         fhir:system [ fhir:v "http://www.sequenceontology.org/"^^xsd:anyURI ] ;
         fhir:code [ fhir:v "SO:0001743" ] ;
         fhir:display [ fhir:v "copy_number_loss" ]
       ] )
     ]
  ] [
     fhir:code [
       fhir:coding ( [
         a loinc:62374-4 ;
         fhir:system [ fhir:v "http://loinc.org"^^xsd:anyURI ] ;
         fhir:code [ fhir:v "62374-4" ]
       ] )
     ] ;
     fhir:value [
       a fhir:CodeableConcept ;
       fhir:coding ( [
         a loinc:LA14029-5 ;
         fhir:system [ fhir:v "http://loinc.org"^^xsd:anyURI ] ;
         fhir:code [ fhir:v "LA14029-5" ] ;
         fhir:display [ fhir:v "GRCh37" ]
       ] )
     ]
  ] ) . # 

<http://hl7.org/fhir/us/mcode/Patient/gx-cancer-patient-adam-anyperson> a fhir:us .

<http://hl7.org/fhir/us/mcode/Practitioner/us-core-practitioner-owen-oncologist> a fhir:us .

# -------------------------------------------------------------------------------------