{
  "resourceType" : "MedicationRequest",
  "id" : "medicationrequest-for-bresentrik",
  "text" : {
    "status" : "generated",
    "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: MedicationRequest</b><a name=\"medicationrequest-for-bresentrik\"> </a><a name=\"hcmedicationrequest-for-bresentrik\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource MedicationRequest &quot;medicationrequest-for-bresentrik&quot; </p></div><p><b>identifier</b>: <code>http://www.bmc.nl/portal/medstatements</code>/1234568900-studyDrug\u00a0(use:\u00a0official)</p><p><b>status</b>: active</p><p><b>intent</b>: order</p><p><b>medication</b>: <a href=\"Medication-bresentrik.html\">Medication/bresentrik: bresentrik 2mg tablet</a></p><p><b>subject</b>: <a href=\"Patient-JanetPatient.html\">Patient/JanetPatient: Janet</a> &quot; CLINICAL TRIAL PATIENT&quot;</p><p><b>supportingInformation</b>: <a href=\"ResearchStudy-BreastCancerTrial.html\">ResearchStudy/BreastCancerTrial</a></p><p><b>authoredOn</b>: 2023-04-05</p><p><b>requester</b>: <span>: Could be reference to inline contained profile such as Reference(practitioner-1) Ronald Bone, MD</span></p><p><b>reasonCode</b>: Breast Cancer <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#254837009)</span></p><p><b>instantiatesCanonical</b>: <a href=\"http://baseUrlOfHospitalHolding/PlanDefinition/protocol-for-the-ResearchStudy\">http://baseUrlOfHospitalHolding/PlanDefinition/protocol-for-the-ResearchStudy</a></p><blockquote><p><b>dosageInstruction</b></p><p><b>sequence</b>: 1</p><p><b>text</b>: 6 mg PO daily for remission induction; adjust dosage to white blood cell (WBC) count.  With hold treatment if WBC is less than 15,000/µL; resume when WBC is greater than 50,000/µL</p><p><b>timing</b>: Once per 1 days</p><p><b>route</b>: Oral route (qualifier value) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#26643006)</span></p><blockquote><p><b>doseAndRate</b></p></blockquote></blockquote><blockquote><p><b>dispenseRequest</b></p><p><b>numberOfRepeatsAllowed</b>: 1</p><p><b>quantity</b>: 600 mg<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mg = 'mg')</span></p><h3>ExpectedSupplyDurations</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Value</b></td><td><b>Unit</b></td><td><b>System</b></td><td><b>Code</b></td></tr><tr><td style=\"display: none\">*</td><td>30</td><td>days</td><td><a href=\"http://terminology.hl7.org/5.5.0/CodeSystem-v3-ucum.html\">Unified Code for Units of Measure (UCUM)</a></td><td>d</td></tr></table></blockquote></div>"
  },
  "identifier" : [{
    "use" : "official",
    "system" : "http://www.bmc.nl/portal/medstatements",
    "value" : "1234568900-studyDrug"
  }],
  "status" : "active",
  "intent" : "order",
  "medicationReference" : {
    "reference" : "Medication/bresentrik",
    "display" : "bresentrik 2mg tablet"
  },
  "subject" : {
    "reference" : "Patient/JanetPatient",
    "display" : "Janet"
  },
  "supportingInformation" : [{
    "reference" : "ResearchStudy/BreastCancerTrial"
  }],
  "authoredOn" : "2023-04-05",
  "requester" : {
    "display" : "Could be reference to inline contained profile such as Reference(practitioner-1) Ronald Bone, MD"
  },
  "reasonCode" : [{
    "coding" : [{
      "system" : "http://snomed.info/sct",
      "code" : "254837009",
      "display" : "Breast Cancer"
    }]
  }],
  "instantiatesCanonical" : ["http://baseUrlOfHospitalHolding/PlanDefinition/protocol-for-the-ResearchStudy"],
  "dosageInstruction" : [{
    "sequence" : 1,
    "text" : "6 mg PO daily for remission induction; adjust dosage to white blood cell (WBC) count.  With hold treatment if WBC is less than 15,000/µL; resume when WBC is greater than 50,000/µL",
    "timing" : {
      "repeat" : {
        "frequency" : 1,
        "period" : 1,
        "periodUnit" : "d"
      }
    },
    "route" : {
      "coding" : [{
        "system" : "http://snomed.info/sct",
        "code" : "26643006",
        "display" : "Oral route (qualifier value)"
      }]
    },
    "doseAndRate" : [{
      "type" : {
        "coding" : [{
          "system" : "http://terminology.hl7.org/CodeSystem/dose-rate-type",
          "code" : "ordered",
          "display" : "Ordered"
        }]
      },
      "doseQuantity" : {
        "value" : 6,
        "unit" : "mg",
        "system" : "http://unitsofmeasure.org",
        "code" : "mg"
      }
    }]
  }],
  "dispenseRequest" : {
    "numberOfRepeatsAllowed" : 1,
    "quantity" : {
      "value" : 600,
      "unit" : "mg",
      "system" : "http://unitsofmeasure.org",
      "code" : "mg"
    },
    "expectedSupplyDuration" : {
      "value" : 30,
      "unit" : "days",
      "system" : "http://unitsofmeasure.org",
      "code" : "d"
    }
  }
}