Profile Comparison between http://hl7.org/fhir/uv/emedicinal-product-info/StructureDefinition/ClinicalUseDefinition-contraindication-uv-epi vs http://hl7.org/fhir/uv/emedicinal-product-info/StructureDefinition/ClinicalUseDefinition-contraindication-uv-epi

Left:ClinicalUseDefinition Contraindication (ePI) (http://hl7.org/fhir/uv/emedicinal-product-info/StructureDefinition/ClinicalUseDefinition-contraindication-uv-epi)
Right:ClinicalUseDefinition Contraindication (ePI) (http://hl7.org/fhir/uv/emedicinal-product-info/StructureDefinition/ClinicalUseDefinition-contraindication-uv-epi)

Messages

ErrorStructureDefinition.versionValues for version differ: '1.0.0' vs '1.1.0'
InformationStructureDefinition.dateValues for date differ: '2023-07-26T13:32:34+00:00' vs '2025-07-21T10:31:44+00:00'

Metadata

NameValueComments
.abstractfalse
    .baseDefinitionhttp://hl7.org/fhir/StructureDefinition/ClinicalUseDefinition
      .copyright
        .date2023-07-26T13:32:34+00:002025-07-21T10:31:44+00:00
        • Values Differ
        .descriptionClinicalUseDefinition Contraindication (ePI)
          .experimental
            .fhirVersion5.0.0
              .jurisdiction
                ..jurisdiction[0]http://unstats.un.org/unsd/methods/m49/m49.htm#001
                  .kindresource
                    .nameClinicalUseDefinitionContraindicationUvEpi
                      .publisherHL7 International - Biomedical Research & Regulation Work Group
                        .purpose
                          .statusactive
                            .titleClinicalUseDefinition Contraindication (ePI)
                              .typeClinicalUseDefinition
                                .urlhttp://hl7.org/fhir/uv/emedicinal-product-info/StructureDefinition/ClinicalUseDefinition-contraindication-uv-epi
                                  .version1.0.01.1.0
                                  • Values Differ

                                  Structure

                                  NameL FlagsL Card.L TypeL Description & ConstraintsR FlagsR Card.R TypeR Description & ConstraintsCommentsdoco
                                  .. ClinicalUseDefinition C0..*ClinicalUseDefinitionA single issue - either an indication, contraindication, interaction or an undesirable effect for a medicinal product, medication, device or procedure
                                  C0..*ClinicalUseDefinitionA single issue - either an indication, contraindication, interaction or an undesirable effect for a medicinal product, medication, device or procedure
                                    ... id Σ0..1idLogical id of this artifactΣ0..1idLogical id of this artifact
                                      ... meta Σ0..1MetaMetadata about the resourceΣ0..1MetaMetadata about the resource
                                        ... implicitRules ?!Σ0..1uriA set of rules under which this content was created?!Σ0..1uriA set of rules under which this content was created
                                          ... text 0..1NarrativeText summary of the resource, for human interpretation
                                          This profile does not constrain the narrative in regard to content, language, or traceability to data elements
                                          0..1NarrativeText summary of the resource, for human interpretation
                                          This profile does not constrain the narrative in regard to content, language, or traceability to data elements
                                            ... contained 0..*ResourceContained, inline Resources
                                            0..*ResourceContained, inline Resources
                                              ... extension 0..*ExtensionAdditional content defined by implementations
                                              0..*ExtensionAdditional content defined by implementations
                                                ... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored
                                                ?!Σ0..*ExtensionExtensions that cannot be ignored
                                                  ... identifier Σ0..*IdentifierBusiness identifier for this clinical use.
                                                  Σ0..*IdentifierBusiness identifier for this clinical use.
                                                    ... type Σ1..1codeindication | contraindication | interaction | undesirable-effect | warning
                                                    Binding: ?? (required): Overall defining type of this clinical use definition.
                                                    Required Pattern: contraindication
                                                    Σ1..1codeindication | contraindication | interaction | undesirable-effect | warning
                                                    Binding: ?? (required): Overall defining type of this clinical use definition.
                                                    Required Pattern: contraindication
                                                      ... category Σ0..*CodeableConceptA categorisation of the issue, primarily for dividing warnings into subject heading areas such as "Pregnancy", "Overdose"
                                                      Binding: ?? (preferred): A categorisation for a clinical use information item.
                                                      Σ0..*CodeableConceptA categorisation of the issue, primarily for dividing warnings into subject heading areas such as "Pregnancy", "Overdose"
                                                      Binding: ?? (preferred): A categorisation for a clinical use information item.
                                                        ... subject Σ1..*Reference(MedicinalProductDefinition (ePI))The medication, product, substance, device, procedure etc. for which this is an indication
                                                        Σ1..*Reference(MedicinalProductDefinition (ePI))The medication, product, substance, device, procedure etc. for which this is an indication
                                                          ... status Σ0..1CodeableConceptDefines whether this clinical use is draft, active or retired
                                                          Binding: ?? (preferred): The lifecycle status of an artifact.
                                                          Σ0..1CodeableConceptDefines whether this clinical use is draft, active or retired
                                                          Binding: ?? (preferred): The lifecycle status of an artifact.
                                                            ... contraindication ΣC1..1BackboneElementSpecifics for when this is a contraindicationΣC1..1BackboneElementSpecifics for when this is a contraindication
                                                              .... id 0..1stringUnique id for inter-element referencing0..1stringUnique id for inter-element referencing
                                                                .... extension 0..*ExtensionAdditional content defined by implementations
                                                                0..*ExtensionAdditional content defined by implementations
                                                                  .... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
                                                                  ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
                                                                    .... diseaseSymptomProcedure Σ0..1CodeableReference(ObservationDefinition)The situation that is being documented as contraindicating against this item
                                                                    Binding: ?? (preferred)
                                                                    Σ0..1CodeableReference(ObservationDefinition)The situation that is being documented as contraindicating against this item
                                                                    Binding: ?? (preferred)
                                                                      .... diseaseStatus Σ0..1CodeableReference(ObservationDefinition)The status of the disease or symptom for the contraindication
                                                                      Binding: ?? (example): The status of a disease or symptom.
                                                                      Σ0..1CodeableReference(ObservationDefinition)The status of the disease or symptom for the contraindication
                                                                      Binding: ?? (example): The status of a disease or symptom.
                                                                        .... comorbidity Σ0..*CodeableReference(ObservationDefinition)A comorbidity (concurrent condition) or coinfection
                                                                        Binding: ?? (example): A symptom, disease or procedure.
                                                                        Σ0..*CodeableReference(ObservationDefinition)A comorbidity (concurrent condition) or coinfection
                                                                        Binding: ?? (example): A symptom, disease or procedure.
                                                                          .... indication Σ0..*Reference(ClinicalUseDefinition)The indication which this is a contraidication for
                                                                          Σ0..*Reference(ClinicalUseDefinition)The indication which this is a contraidication for
                                                                            .... applicability 0..1ExpressionAn expression that returns true or false, indicating whether the indication is applicable or not, after having applied its other elements0..1ExpressionAn expression that returns true or false, indicating whether the indication is applicable or not, after having applied its other elements
                                                                              .... otherTherapy Σ0..*BackboneElementInformation about use of the product in relation to other therapies described as part of the contraindication
                                                                              Σ0..*BackboneElementInformation about use of the product in relation to other therapies described as part of the contraindication
                                                                                ..... id 0..1stringUnique id for inter-element referencing0..1stringUnique id for inter-element referencing
                                                                                  ..... extension 0..*ExtensionAdditional content defined by implementations
                                                                                  0..*ExtensionAdditional content defined by implementations
                                                                                    ..... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
                                                                                    ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
                                                                                      ..... relationshipType Σ1..1CodeableConceptThe type of relationship between the product indication/contraindication and another therapy
                                                                                      Binding: ?? (preferred): Classification of relationship between a therapy and a contraindication or an indication.
                                                                                      Σ1..1CodeableConceptThe type of relationship between the product indication/contraindication and another therapy
                                                                                      Binding: ?? (preferred): Classification of relationship between a therapy and a contraindication or an indication.
                                                                                        ..... treatment Σ1..1CodeableReference(MedicinalProductDefinition | Medication | Substance | SubstanceDefinition | NutritionProduct | BiologicallyDerivedProduct | ActivityDefinition)Reference to a specific medication, substance etc. as part of an indication or contraindication
                                                                                        Binding: ?? (example): A therapy.
                                                                                        Σ1..1CodeableReference(MedicinalProductDefinition | Medication | Substance | SubstanceDefinition | NutritionProduct | BiologicallyDerivedProduct | ActivityDefinition)Reference to a specific medication, substance etc. as part of an indication or contraindication
                                                                                        Binding: ?? (example): A therapy.
                                                                                          ... indication ΣC0..0ΣC0..0
                                                                                            .... id 0..1stringUnique id for inter-element referencing0..1stringUnique id for inter-element referencing
                                                                                              .... extension 0..*ExtensionAdditional content defined by implementations
                                                                                              0..*ExtensionAdditional content defined by implementations
                                                                                                .... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
                                                                                                ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
                                                                                                  .... diseaseSymptomProcedure Σ0..1CodeableReference(ObservationDefinition)The situation that is being documented as an indicaton for this item
                                                                                                  Binding: ?? (example): A symptom, disease or procedure.
                                                                                                  Σ0..1CodeableReference(ObservationDefinition)The situation that is being documented as an indicaton for this item
                                                                                                  Binding: ?? (example): A symptom, disease or procedure.
                                                                                                    .... diseaseStatus Σ0..1CodeableReference(ObservationDefinition)The status of the disease or symptom for the indication
                                                                                                    Binding: ?? (example): The status of a disease or symptom.
                                                                                                    Σ0..1CodeableReference(ObservationDefinition)The status of the disease or symptom for the indication
                                                                                                    Binding: ?? (example): The status of a disease or symptom.
                                                                                                      .... comorbidity Σ0..*CodeableReference(ObservationDefinition)A comorbidity or coinfection as part of the indication
                                                                                                      Binding: ?? (example): A symptom, disease or procedure.
                                                                                                      Σ0..*CodeableReference(ObservationDefinition)A comorbidity or coinfection as part of the indication
                                                                                                      Binding: ?? (example): A symptom, disease or procedure.
                                                                                                        .... intendedEffect Σ0..1CodeableReference(ObservationDefinition)The intended effect, aim or strategy to be achieved
                                                                                                        Binding: ?? (preferred): The overall intended use of a product.
                                                                                                        Σ0..1CodeableReference(ObservationDefinition)The intended effect, aim or strategy to be achieved
                                                                                                        Binding: ?? (preferred): The overall intended use of a product.
                                                                                                          .... duration[x] Σ0..1Range, stringTiming or duration informationΣ0..1Range, stringTiming or duration information
                                                                                                            .... undesirableEffect Σ0..*Reference(ClinicalUseDefinition)An unwanted side effect or negative outcome of the subject of this resource when being used for this indication
                                                                                                            Σ0..*Reference(ClinicalUseDefinition)An unwanted side effect or negative outcome of the subject of this resource when being used for this indication
                                                                                                              .... applicability 0..1ExpressionAn expression that returns true or false, indicating whether the indication is applicable or not, after having applied its other elements0..1ExpressionAn expression that returns true or false, indicating whether the indication is applicable or not, after having applied its other elements
                                                                                                                .... otherTherapy Σ0..*See otherTherapy (ClinicalUseDefinition)The use of the medicinal product in relation to other therapies described as part of the indication
                                                                                                                Σ0..*See otherTherapy (ClinicalUseDefinition)The use of the medicinal product in relation to other therapies described as part of the indication
                                                                                                                  ..... id 0..1stringUnique id for inter-element referencing0..1stringUnique id for inter-element referencing
                                                                                                                    ..... extension 0..*ExtensionAdditional content defined by implementations
                                                                                                                    0..*ExtensionAdditional content defined by implementations
                                                                                                                      ..... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
                                                                                                                      ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
                                                                                                                        ..... relationshipType Σ1..1CodeableConceptThe type of relationship between the product indication/contraindication and another therapy
                                                                                                                        Binding: ?? (preferred): Classification of relationship between a therapy and a contraindication or an indication.
                                                                                                                        Σ1..1CodeableConceptThe type of relationship between the product indication/contraindication and another therapy
                                                                                                                        Binding: ?? (preferred): Classification of relationship between a therapy and a contraindication or an indication.
                                                                                                                          ..... treatment Σ1..1CodeableReference(MedicinalProductDefinition | Medication | Substance | SubstanceDefinition | NutritionProduct | BiologicallyDerivedProduct | ActivityDefinition)Reference to a specific medication, substance etc. as part of an indication or contraindication
                                                                                                                          Binding: ?? (example): A therapy.
                                                                                                                          Σ1..1CodeableReference(MedicinalProductDefinition | Medication | Substance | SubstanceDefinition | NutritionProduct | BiologicallyDerivedProduct | ActivityDefinition)Reference to a specific medication, substance etc. as part of an indication or contraindication
                                                                                                                          Binding: ?? (example): A therapy.
                                                                                                                            ... interaction ΣC0..0ΣC0..0
                                                                                                                              .... id 0..1stringUnique id for inter-element referencing0..1stringUnique id for inter-element referencing
                                                                                                                                .... extension 0..*ExtensionAdditional content defined by implementations
                                                                                                                                0..*ExtensionAdditional content defined by implementations
                                                                                                                                  .... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
                                                                                                                                  ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
                                                                                                                                    .... interactant Σ0..*BackboneElementThe specific medication, product, food etc. or laboratory test that interacts
                                                                                                                                    Σ0..*BackboneElementThe specific medication, product, food etc. or laboratory test that interacts
                                                                                                                                      ..... id 0..1stringUnique id for inter-element referencing0..1stringUnique id for inter-element referencing
                                                                                                                                        ..... extension 0..*ExtensionAdditional content defined by implementations
                                                                                                                                        0..*ExtensionAdditional content defined by implementations
                                                                                                                                          ..... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
                                                                                                                                          ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
                                                                                                                                            ..... item[x] Σ1..1Reference(MedicinalProductDefinition | Medication | Substance | NutritionProduct | BiologicallyDerivedProduct | ObservationDefinition), CodeableConceptThe specific medication, product, food etc. or laboratory test that interacts
                                                                                                                                            Binding: ?? (example): An interactant - a substance that may have a clinically significant effect on another.
                                                                                                                                            Σ1..1Reference(MedicinalProductDefinition | Medication | Substance | NutritionProduct | BiologicallyDerivedProduct | ObservationDefinition), CodeableConceptThe specific medication, product, food etc. or laboratory test that interacts
                                                                                                                                            Binding: ?? (example): An interactant - a substance that may have a clinically significant effect on another.
                                                                                                                                              .... type Σ0..1CodeableConceptThe type of the interaction e.g. drug-drug interaction, drug-lab test interaction
                                                                                                                                              Binding: ?? (example): A categorisation for an interaction between two substances.
                                                                                                                                              Σ0..1CodeableConceptThe type of the interaction e.g. drug-drug interaction, drug-lab test interaction
                                                                                                                                              Binding: ?? (example): A categorisation for an interaction between two substances.
                                                                                                                                                .... effect Σ0..1CodeableReference(ObservationDefinition)The effect of the interaction, for example "reduced gastric absorption of primary medication"
                                                                                                                                                Binding: ?? (example): A interaction effect of clinical use of a medication or other substance.
                                                                                                                                                Σ0..1CodeableReference(ObservationDefinition)The effect of the interaction, for example "reduced gastric absorption of primary medication"
                                                                                                                                                Binding: ?? (example): A interaction effect of clinical use of a medication or other substance.
                                                                                                                                                  .... incidence Σ0..1CodeableConceptThe incidence of the interaction, e.g. theoretical, observed
                                                                                                                                                  Binding: ?? (example): A categorisation for incidence of occurence of an interaction.
                                                                                                                                                  Σ0..1CodeableConceptThe incidence of the interaction, e.g. theoretical, observed
                                                                                                                                                  Binding: ?? (example): A categorisation for incidence of occurence of an interaction.
                                                                                                                                                    .... management Σ0..*CodeableConceptActions for managing the interaction
                                                                                                                                                    Binding: ?? (example): A type of management for an interaction of a medication or other substance.
                                                                                                                                                    Σ0..*CodeableConceptActions for managing the interaction
                                                                                                                                                    Binding: ?? (example): A type of management for an interaction of a medication or other substance.
                                                                                                                                                      ... population Σ0..*Reference(Group)The population group to which this applies
                                                                                                                                                      Σ0..*Reference(Group)The population group to which this applies
                                                                                                                                                        ... library Σ0..*canonical(Library)Logic used by the clinical use definition
                                                                                                                                                        Σ0..*canonical(Library)Logic used by the clinical use definition
                                                                                                                                                          ... undesirableEffect ΣC0..0ΣC0..0
                                                                                                                                                            .... id 0..1stringUnique id for inter-element referencing0..1stringUnique id for inter-element referencing
                                                                                                                                                              .... extension 0..*ExtensionAdditional content defined by implementations
                                                                                                                                                              0..*ExtensionAdditional content defined by implementations
                                                                                                                                                                .... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
                                                                                                                                                                ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
                                                                                                                                                                  .... symptomConditionEffect Σ0..1CodeableReference(ObservationDefinition)The situation in which the undesirable effect may manifest
                                                                                                                                                                  Binding: ?? (example): An undesirable effect of clinical use.
                                                                                                                                                                  Σ0..1CodeableReference(ObservationDefinition)The situation in which the undesirable effect may manifest
                                                                                                                                                                  Binding: ?? (example): An undesirable effect of clinical use.
                                                                                                                                                                    .... classification Σ0..1CodeableConceptHigh level classification of the effect
                                                                                                                                                                    Binding: ?? (example): A categorisation for an undesirable effect.
                                                                                                                                                                    Σ0..1CodeableConceptHigh level classification of the effect
                                                                                                                                                                    Binding: ?? (example): A categorisation for an undesirable effect.
                                                                                                                                                                      .... frequencyOfOccurrence Σ0..1CodeableConceptHow often the effect is seen
                                                                                                                                                                      Binding: ?? (example): A categorisation for a frequency of occurence of an undesirable effect.
                                                                                                                                                                      Σ0..1CodeableConceptHow often the effect is seen
                                                                                                                                                                      Binding: ?? (example): A categorisation for a frequency of occurence of an undesirable effect.
                                                                                                                                                                        ... warning ΣC0..0ΣC0..0
                                                                                                                                                                          .... id 0..1stringUnique id for inter-element referencing0..1stringUnique id for inter-element referencing
                                                                                                                                                                            .... extension 0..*ExtensionAdditional content defined by implementations
                                                                                                                                                                            0..*ExtensionAdditional content defined by implementations
                                                                                                                                                                              .... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
                                                                                                                                                                              ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
                                                                                                                                                                                .... description Σ0..1markdownA textual definition of this warning, with formattingΣ0..1markdownA textual definition of this warning, with formatting
                                                                                                                                                                                  .... code Σ0..1CodeableConceptA coded or unformatted textual definition of this warning
                                                                                                                                                                                  Binding: ?? (example): Classification of warning type.
                                                                                                                                                                                  Σ0..1CodeableConceptA coded or unformatted textual definition of this warning
                                                                                                                                                                                  Binding: ?? (example): Classification of warning type.

                                                                                                                                                                                    doco Documentation for this format