Profile Comparison between http://hl7.org/fhir/uv/emedicinal-product-info/StructureDefinition/SubstanceDefinition-uv-epi vs http://hl7.org/fhir/uv/emedicinal-product-info/StructureDefinition/SubstanceDefinition-uv-epi

Messages

Metadata

Name	Value		Comments
abstract	false
baseDefinition	http://hl7.org/fhir/StructureDefinition/SubstanceDefinition
copyright
date	2023-07-26T13:32:34+00:00	2026-05-03T19:07:24+00:00	Values Differ
description	SubstanceDefinition (ePI)
experimental
fhirVersion	5.0.0
jurisdiction
jurisdiction[0]	http://unstats.un.org/unsd/methods/m49/m49.htm#001
kind	resource
name	SubstanceDefinitionUvEpi
publisher	HL7 International - Biomedical Research & Regulation Work Group	HL7 International / Biomedical Research and Regulation	Values Differ
purpose
status	active
title	SubstanceDefinition (ePI)
type	SubstanceDefinition
url	http://hl7.org/fhir/uv/emedicinal-product-info/StructureDefinition/SubstanceDefinition-uv-epi
version	1.0.0	1.1.0	Values Differ

Structure

Name	L Flags	L Card.	L Type	L Description & Constraints	R Flags	R Card.	R Type	R Description & Constraints	Comments
SubstanceDefinition		0..*	SubstanceDefinition	The detailed description of a substance, typically at a level beyond what is used for prescribing		0..*	SubstanceDefinition	The detailed description of a substance, typically at a level beyond what is used for prescribing
id	Σ	0..1	id	Logical id of this artifact	Σ	0..1	id	Logical id of this artifact
meta	Σ	0..1	Meta	Metadata about the resource	Σ	0..1	Meta	Metadata about the resource
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created	?!Σ	0..1	uri	A set of rules under which this content was created
language		0..1	code	Language of the resource content Binding: ?? (required): IETF language tag for a human language Additional Bindings Purpose ?? Starter		0..1	code	Language of the resource content Binding: ?? (required): IETF language tag for a human language Additional Bindings Purpose ?? Starter
text		0..1	Narrative	Text summary of the resource, for human interpretation This profile does not constrain the narrative in regard to content, language, or traceability to data elements		0..1	Narrative	Text summary of the resource, for human interpretation This profile does not constrain the narrative in regard to content, language, or traceability to data elements
contained		0..*	Resource	Contained, inline Resources		0..*	Resource	Contained, inline Resources
extension		0..*	Extension	Additional content defined by implementations		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored	?!Σ	0..*	Extension	Extensions that cannot be ignored
identifier	Σ	1..*	Identifier	Identifier by which this substance is known	Σ	1..*	Identifier	Identifier by which this substance is known
id		0..1	id	Unique id for inter-element referencing		0..1	id	Unique id for inter-element referencing
Slices for extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
use	?!Σ	0..1	code	usual | official | temp | secondary | old (If known) Binding: ?? (required): Identifies the purpose for this identifier, if known .	?!Σ	0..1	code	usual | official | temp | secondary | old (If known) Binding: ?? (required): Identifies the purpose for this identifier, if known .
type	Σ	0..1	CodeableConcept	Description of identifier Binding: ?? (extensible): A coded type for an identifier that can be used to determine which identifier to use for a specific purpose.	Σ	0..1	CodeableConcept	Description of identifier Binding: ?? (extensible): A coded type for an identifier that can be used to determine which identifier to use for a specific purpose.
system	Σ	1..1	uri	The namespace for the identifier value Example General: http://www.acme.com/identifiers/patient	Σ	1..1	uri	The namespace for the identifier value Example General: http://www.acme.com/identifiers/patient
value	ΣC	1..1	string	The value that is unique Example General: 123456	ΣC	1..1	string	The value that is unique Example General: 123456
period	Σ	0..1	Period	Time period when id is/was valid for use	Σ	0..1	Period	Time period when id is/was valid for use
assigner	Σ	0..1	Reference(Organization)	Organization that issued id (may be just text)	Σ	0..1	Reference(Organization)	Organization that issued id (may be just text)
version	Σ	0..1	string	A business level version identifier of the substance	Σ	0..1	string	A business level version identifier of the substance.
status	Σ	0..1	CodeableConcept	draft|active|retired|unknown Binding: ?? (preferred): The lifecycle status of an artifact.	Σ	0..1	CodeableConcept	Status of substance within the catalogue e.g. active, retired Binding: ?? (preferred): The lifecycle status of an artifact.	Example/preferred bindings differ at SubstanceDefinition.status using binding from SubstanceDefinitionUvEpi
id						0..1	id	Unique id for inter-element referencing	Added this element
Slices for extension						0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url	Added this element
coding					Σ	1..1	Coding	Code defined by a terminology system	Added this element
text					Σ	0..1	string	Plain text representation of the concept	Added this element
classification	Σ	0..*	CodeableConcept	A categorization, high level e.g. polymer or nucleic acid, or food, chemical, biological, or lower e.g. polymer linear or branch chain, or type of impurity	Σ	0..*	CodeableConcept	A categorization, high level e.g. polymer or nucleic acid, or food, chemical, biological, or lower e.g. polymer linear or branch chain, or type of impurity
id						0..1	id	Unique id for inter-element referencing	Added this element
Slices for extension						0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url	Added this element
coding					Σ	1..1	Coding	Code defined by a terminology system	Added this element
text					Σ	0..1	string	Plain text representation of the concept	Added this element
domain	Σ	0..1	CodeableConcept	If the substance applies to human or veterinary use Binding: ?? (example)	Σ	0..1	CodeableConcept	If the substance applies to human or veterinary use Binding: ?? (example): Applicable domain for this product (e.g. human, veterinary).
id						0..1	id	Unique id for inter-element referencing	Added this element
Slices for extension						0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url	Added this element
coding					Σ	1..1	Coding	Code defined by a terminology system	Added this element
text					Σ	0..1	string	Plain text representation of the concept	Added this element
grade	Σ	0..*	CodeableConcept	The quality standard, established benchmark, to which substance complies (e.g. USP/NF, BP) Binding: ?? (example): The quality standard, established benchmark, to which a substance complies	Σ	0..*	CodeableConcept	The quality standard, established benchmark, to which substance complies (e.g. USP/NF, BP) Binding: ?? (example): The quality standard, established benchmark, to which a substance complies
id						0..1	id	Unique id for inter-element referencing	Added this element
Slices for extension						0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url	Added this element
coding					Σ	1..1	Coding	Code defined by a terminology system	Added this element
text					Σ	0..1	string	Plain text representation of the concept	Added this element
description	Σ	0..1	markdown	Textual description of the substance.	Σ	0..1	markdown	Textual description of the substance.
informationSource	Σ	0..*	Reference(Citation)	Supporting literature	Σ	0..*	Reference(Citation)	Supporting literature
note	Σ	0..*	Annotation	Textual comment about the substance's catalogue or registry record	Σ	0..*	Annotation	Textual comment about the substance's catalogue or registry record
manufacturer	Σ	0..*	Reference(Organization (ePI))	The entity that creates, makes, produces or fabricates the substance	Σ	0..*	Reference(Organization (ePI))	The entity that creates, makes, produces or fabricates the substance
supplier	Σ	0..*	Reference(Organization)	An entity that is the source for the substance. It may be different from the manufacturer	Σ	0..*	Reference(Organization)	An entity that is the source for the substance. It may be different from the manufacturer
moiety	Σ	0..*	BackboneElement	Moiety, for structural modifications	Σ	0..*	BackboneElement	Moiety, for structural modifications
id		0..1	string	Unique id for inter-element referencing		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
role	Σ	0..1	CodeableConcept	Role that the moiety is playing	Σ	0..1	CodeableConcept	Role that the moiety is playing
identifier	Σ	0..1	Identifier	Identifier by which this moiety substance is known	Σ	0..1	Identifier	Identifier by which this moiety substance is known
id						0..1	id	Unique id for inter-element referencing	Added this element
Slices for extension						0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url	Added this element
use					?!Σ	0..1	code	usual | official | temp | secondary | old (If known) Binding: ?? (required): Identifies the purpose for this identifier, if known .	Added this element
type					Σ	0..1	CodeableConcept	Description of identifier Binding: ?? (extensible): A coded type for an identifier that can be used to determine which identifier to use for a specific purpose.	Added this element
system					Σ	1..1	uri	The namespace for the identifier value Example General: http://www.acme.com/identifiers/patient	Added this element
value					ΣC	1..1	string	The value that is unique Example General: 123456	Added this element
period					Σ	0..1	Period	Time period when id is/was valid for use	Added this element
assigner					Σ	0..1	Reference(Organization)	Organization that issued id (may be just text)	Added this element
name	Σ	0..1	string	Textual name for this moiety substance	Σ	0..1	string	Name of the moiety
stereochemistry	Σ	0..1	CodeableConcept	Stereochemistry type Binding: ?? (example): The optical rotation type of a substance.	Σ	0..1	CodeableConcept	Stereochemistry type Binding: ?? (example): The optical rotation type of a substance.
id						0..1	id	Unique id for inter-element referencing	Added this element
Slices for extension						0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url	Added this element
coding					Σ	1..1	Coding	Code defined by a terminology system	Added this element
text					Σ	0..1	string	Plain text representation of the concept	Added this element
opticalActivity	Σ	0..1	CodeableConcept	Optical activity type Binding: ?? (example): The optical rotation type of a substance.	Σ	0..1	CodeableConcept	Optical activity type Binding: ?? (example): The optical rotation type of a substance.
molecularFormula	Σ	0..1	string	Molecular formula for this moiety (e.g. with the Hill system)	Σ	0..1	string	Molecular formula of the moiety
amount[x]	Σ	0..1	Quantity, string	Quantitative value for this moiety	Σ	0..1	Quantity, string	Quantitative value for this moiety
measurementType	Σ	0..1	CodeableConcept	The measurement type of the quantitative value Binding: ?? (example): The relationship between two substance types.	Σ	0..1	CodeableConcept	The measurement type of the quantitative value Binding: ?? (example): The relationship between two substance types.
characterization	Σ	0..*	BackboneElement	General specifications for this substance	Σ	0..*	BackboneElement	General specifications for this substance
id		0..1	string	Unique id for inter-element referencing		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
technique	Σ	0..1	CodeableConcept	The method used to find the characterization e.g. HPLC Binding: ?? (example): The method used to elucidate the characterization of the drug substance.	Σ	0..1	CodeableConcept	The method used to find the characterization e.g. HPLC Binding: ?? (example): The method used to elucidate the characterization of the drug substance.
form	Σ	0..1	CodeableConcept	Describes the nature of the chemical entity and explains, for instance, whether this is a base or a salt form Binding: ?? (example)	Σ	0..1	CodeableConcept	Describes the nature of the chemical entity and explains, for instance, whether this is a base or a salt form Binding: ?? (example)
description	Σ	0..1	markdown	The description or justification in support of the interpretation of the data file	Σ	0..1	markdown	The description or justification in support of the interpretation of the data file
file	Σ	0..*	Attachment	The data produced by the analytical instrument or a pictorial representation of that data. Examples: a JCAMP, JDX, or ADX file, or a chromatogram or spectrum analysis	Σ	0..*	Attachment	The data produced by the analytical instrument or a pictorial representation of that data. Examples: a JCAMP, JDX, or ADX file, or a chromatogram or spectrum analysis
property	Σ	0..*	BackboneElement	General specifications for this substance	Σ	0..*	BackboneElement	General specifications for this substance
id		0..1	string	Unique id for inter-element referencing		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
type	Σ	1..1	CodeableConcept	A code expressing the type of property Binding: ?? (example): This value set includes all observable entity codes from SNOMED CT - provided as an exemplar value set.	Σ	1..1	CodeableConcept	A code expressing the type of property Binding: ?? (example): This value set includes all observable entity codes from SNOMED CT - provided as an exemplar value set.
value[x]	Σ	0..1	CodeableConcept, Quantity, date, boolean, Attachment	A value for the property	Σ	0..1	CodeableConcept, Quantity, date, boolean, Attachment	A value for the property
referenceInformation	Σ	0..1	Reference(SubstanceReferenceInformation)	General information detailing this substance	Σ	0..1	Reference(SubstanceReferenceInformation)	General information detailing this substance
molecularWeight	Σ	0..*	BackboneElement	The average mass of a molecule of a compound	Σ	0..*	BackboneElement	The molecular weight or weight range
id		0..1	string	Unique id for inter-element referencing		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
method	Σ	0..1	CodeableConcept	The method by which the weight was determined Binding: ?? (example): The method by which the substance weight was measured.	Σ	0..1	CodeableConcept	The method by which the weight was determined Binding: ?? (example): The method by which the substance weight was measured.
type	Σ	0..1	CodeableConcept	Type of molecular weight e.g. exact, average, weight average Binding: ?? (example): The type of substance weight measurement.	Σ	0..1	CodeableConcept	Type of molecular weight e.g. exact, average, weight average Binding: ?? (example): The type of substance weight measurement.
amount	Σ	1..1	Quantity	The molecular weight.	Σ	1..1	Quantity	The molecular weight or weight range
id		0..1	id	Unique id for inter-element referencing					Removed this element
Slices for extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url					Removed this element
value	Σ	0..1	decimal	numerical value.					Removed this element
comparator	?!Σ	0..1	code	< | <= | >= | > | ad - how to understand the value Binding: ?? (required): How the Quantity should be understood and represented.					Removed this element
unit	Σ	0..1	string	Unit of measure.					Removed this element
system	ΣC	0..1	uri	System that defines coded unit form					Removed this element
code	ΣC	0..1	code	coded form of the unit of measure.					Removed this element
structure	Σ	0..1	BackboneElement	Structural information	Σ	0..1	BackboneElement	Structural information
id		0..1	string	Unique id for inter-element referencing		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
stereochemistry	Σ	0..1	CodeableConcept	Stereochemistry type Binding: ?? (example): The optical rotation type of a substance.	Σ	0..1	CodeableConcept	Stereochemistry type Binding: ?? (example): The optical rotation type of a substance.
id						0..1	id	Unique id for inter-element referencing	Added this element
Slices for extension						0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url	Added this element
coding					Σ	1..1	Coding	Code defined by a terminology system	Added this element
text					Σ	0..1	string	Plain text representation of the concept	Added this element
opticalActivity	Σ	0..1	CodeableConcept	Optical activity type Binding: ?? (example): The optical rotation type of a substance.	Σ	0..1	CodeableConcept	Optical activity type Binding: ?? (example): The optical rotation type of a substance.
molecularFormula	Σ	0..1	string	Molecular formula (e.g. using the Hill system).	Σ	0..1	string	Molecular formula
molecularFormulaByMoiety	Σ	0..1	string	Specified per moiety according to the Hill system	Σ	0..1	string	Specified per moiety according to the Hill system
molecularWeight	Σ	0..1	See molecularWeight (SubstanceDefinition)	The molecular weight or weight range	Σ	0..1	See molecularWeight (SubstanceDefinition)	The molecular weight or weight range
technique	Σ	0..*	CodeableConcept	The method used to find the structure e.g. X-ray, NMR Binding: ?? (example): The method used to elucidate the structure of the drug substance.	Σ	0..*	CodeableConcept	The method used to find the structure e.g. X-ray, NMR Binding: ?? (example): The method used to elucidate the structure of the drug substance.
sourceDocument	Σ	0..*	Reference(DocumentReference)	Source of information for the structure	Σ	0..*	Reference(DocumentReference)	Source of information for the structure
representation	Σ	0..*	BackboneElement	A depiction of the structure of the substance	Σ	0..*	BackboneElement	A depiction of the structure of the substance
id		0..1	string	Unique id for inter-element referencing		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
type	Σ	0..1	CodeableConcept	The kind of structural representation (e.g. full, partial) Binding: ?? (example): A format of a substance representation.	Σ	0..1	CodeableConcept	The kind of structural representation (e.g. full, partial) Binding: ?? (example): A format of a substance representation.
representation	Σ	0..1	string	The structural representation as a text string in a standard format	Σ	0..1	string	The structural representation as a text string in a standard format
format	Σ	0..1	CodeableConcept	The format of the representation e.g. InChI, SMILES, MOLFILE (note: not the physical file format) Binding: ?? (example): A format of a substance representation.	Σ	0..1	CodeableConcept	The format of the representation e.g. InChI, SMILES, MOLFILE (note: not the physical file format) Binding: ?? (example): A format of a substance representation.
document	Σ	0..1	Reference(DocumentReference)	An attachment with the structural representation e.g. a structure graphic or AnIML file	Σ	0..1	Reference(DocumentReference)	An attachment with the structural representation e.g. a structure graphic or AnIML file
code	Σ	0..*	BackboneElement	Codes associated with the substance.	Σ	0..*	BackboneElement	Codes associated with the substance
id		0..1	string	Unique id for inter-element referencing		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
code	Σ	0..1	CodeableConcept	The specific code Binding: ?? (example)	Σ	0..1	CodeableConcept	The specific code
status	Σ	0..1	CodeableConcept	Status of the code assignment, for example 'provisional', 'approved' Binding: ?? (preferred): The lifecycle status of an artifact.	Σ	0..1	CodeableConcept	Status of the code assignment, for example 'provisional', 'approved' Binding: ?? (preferred): The lifecycle status of an artifact.	Example/preferred bindings differ at SubstanceDefinition.code.status using binding from SubstanceDefinitionUvEpi
statusDate	Σ	0..1	dateTime	The date at which the code status was changed	Σ	0..1	dateTime	The date at which the code status was changed
note	Σ	0..*	Annotation	Any comment can be provided in this field	Σ	0..*	Annotation	Any comment can be provided in this field
source	Σ	0..*	Reference(DocumentReference)	Supporting literature	Σ	0..*	Reference(DocumentReference)	Supporting literature
name	Σ	0..*	BackboneElement	International Non-Proprietary Name (INN) of the substance; or United States Adopted Name (USAN) if applicable.	Σ	0..*	BackboneElement	Names for the substance
id		0..1	string	Unique id for inter-element referencing		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
name	Σ	1..1	string	The actual name	Σ	1..1	string	The actual name
type	Σ	0..1	CodeableConcept	Name type e.g. 'scientific, 'brand' Binding: ?? (example): The type of a name given to a substance.	Σ	0..1	CodeableConcept	Name type e.g. 'systematic', 'scientific, 'brand' Binding: ?? (example): The type of a name given to a substance.
id						0..1	id	Unique id for inter-element referencing	Added this element
Slices for extension						0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url	Added this element
coding					Σ	1..1	Coding	Code defined by a terminology system	Added this element
text					Σ	0..1	string	Plain text representation of the concept	Added this element
status	Σ	0..1	CodeableConcept	The status of the name e.g. 'current', 'proposed' Binding: ?? (preferred): The lifecycle status of an artifact.	Σ	0..1	CodeableConcept	The status of the name e.g. 'current', 'proposed' Binding: ?? (preferred): The lifecycle status of an artifact.	Example/preferred bindings differ at SubstanceDefinition.name.status using binding from SubstanceDefinitionUvEpi
preferred	Σ	0..1	boolean	If this is the preferred name for this substance	Σ	0..1	boolean	If this is the preferred name for this language
language	Σ	0..*	CodeableConcept	Human language that the name is written in Binding: ?? (required): IETF language tag for a human language Additional Bindings Purpose ?? Starter	Σ	0..*	CodeableConcept	Human language that the name is written in Binding: ?? (required): IETF language tag for a human language Additional Bindings Purpose ?? Starter
id						0..1	id	Unique id for inter-element referencing	Added this element
Slices for extension						0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url	Added this element
coding					Σ	1..1	Coding	Code defined by a terminology system	Added this element
text					Σ	0..1	string	Plain text representation of the concept	Added this element
domain	Σ	0..*	CodeableConcept	The use context of this name e.g. as an active ingredient or as a food colour additive Binding: ?? (example): The use context of a substance name for example if there is a different name when used as a drug active ingredient as opposed to a food colour additive.	Σ	0..*	CodeableConcept	The use context of this name e.g. as an active ingredient or as a food colour additive Binding: ?? (example): The use context of a substance name for example if there is a different name when used as a drug active ingredient as opposed to a food colour additive.
jurisdiction	Σ	0..*	CodeableConcept	The jurisdiction where this name applies Binding: ?? (example): Jurisdiction codes	Σ	0..*	CodeableConcept	The jurisdiction where this name applies Binding: ?? (example): Jurisdiction codes
synonym	Σ	0..*	See name (SubstanceDefinition)	A synonym of this particular name, by which the substance is also known	Σ	0..*	See name (SubstanceDefinition)	A synonym of this particular name, by which the substance is also known
translation	Σ	0..*	See name (SubstanceDefinition)	A translation for this name into another human language	Σ	0..*	See name (SubstanceDefinition)	A translation for this name into another human language
official	Σ	0..*	BackboneElement	Details of the official nature of this name	Σ	0..*	BackboneElement	Details of the official nature of this name
id		0..1	string	Unique id for inter-element referencing		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
authority	Σ	0..1	CodeableConcept	Which authority uses this official name Binding: ?? (preferred): An authority that officates substance names.	Σ	0..1	CodeableConcept	Which authority uses this official name Binding: ?? (preferred): An authority that officates substance names.	Example/preferred bindings differ at SubstanceDefinition.name.official.authority using binding from SubstanceDefinitionUvEpi
status	Σ	0..1	CodeableConcept	The status of the official name, for example 'draft', 'active' Binding: ?? (preferred): The lifecycle status of an artifact.	Σ	0..1	CodeableConcept	The status of the official name, for example 'draft', 'active' Binding: ?? (preferred): The lifecycle status of an artifact.	Example/preferred bindings differ at SubstanceDefinition.name.official.status using binding from SubstanceDefinitionUvEpi
date	Σ	0..1	dateTime	Date of official name change	Σ	0..1	dateTime	Date of official name change
source	Σ	0..*	Reference(DocumentReference)	Supporting literature	Σ	0..*	Reference(DocumentReference)	Supporting literature
relationship	Σ	0..*	BackboneElement	A link between this substance and another	Σ	0..*	BackboneElement	A link between this substance and another
id		0..1	string	Unique id for inter-element referencing		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
substanceDefinition[x]	Σ	0..1	Reference(SubstanceDefinition), CodeableConcept	A pointer to another substance, as a resource or a representational code	Σ	0..1	Reference(SubstanceDefinition), CodeableConcept	A pointer to another substance, as a resource or a representational code
type	Σ	1..1	CodeableConcept	For example "salt to parent", "active moiety" Binding: ?? (example): The relationship between two substance types.	Σ	1..1	CodeableConcept	For example "salt to parent", "active moiety" Binding: ?? (example): The relationship between two substance types.
isDefining	Σ	0..1	boolean	For example where an enzyme strongly bonds with a particular substance, this is a defining relationship for that enzyme, out of several possible relationships	Σ	0..1	boolean	For example where an enzyme strongly bonds with a particular substance, this is a defining relationship for that enzyme, out of several possible relationships
amount[x]	Σ	0..1	Quantity, Ratio, string	A numeric factor for the relationship, e.g. that a substance salt has some percentage of active substance in relation to some other	Σ	0..1	Quantity, Ratio, string	A numeric factor for the relationship, e.g. that a substance salt has some percentage of active substance in relation to some other
ratioHighLimitAmount	Σ	0..1	Ratio	For use when the numeric has an uncertain range	Σ	0..1	Ratio	For use when the numeric has an uncertain range
comparator	Σ	0..1	CodeableConcept	An operator for the amount, for example "average", "approximately", "less than" Binding: ?? (example): The relationship between two substance types.	Σ	0..1	CodeableConcept	An operator for the amount, for example "average", "approximately", "less than" Binding: ?? (example): The relationship between two substance types.
source	Σ	0..*	Reference(DocumentReference)	Supporting literature	Σ	0..*	Reference(DocumentReference)	Supporting literature
nucleicAcid	Σ	0..1	Reference(SubstanceNucleicAcid)	Data items specific to nucleic acids	Σ	0..1	Reference(SubstanceNucleicAcid)	Data items specific to nucleic acids
polymer	Σ	0..1	Reference(SubstancePolymer)	Data items specific to polymers	Σ	0..1	Reference(SubstancePolymer)	Data items specific to polymers
protein	Σ	0..1	Reference(SubstanceProtein)	Data items specific to proteins	Σ	0..1	Reference(SubstanceProtein)	Data items specific to proteins
sourceMaterial	Σ	0..1	BackboneElement	Material or taxonomic/anatomical source	Σ	0..1	BackboneElement	Material or taxonomic/anatomical source
id		0..1	string	Unique id for inter-element referencing		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
type	Σ	0..1	CodeableConcept	Classification of the origin of the raw material. e.g. cat hair is an Animal source type Binding: ?? (example): A classification that provides the origin of the substance raw material.	Σ	0..1	CodeableConcept	Classification of the origin of the raw material. e.g. cat hair is an Animal source type Binding: ?? (example): A classification that provides the origin of the substance raw material.
genus	Σ	0..1	CodeableConcept	The genus of an organism e.g. the Latin epithet of the plant/animal scientific name Binding: ?? (example): The genus of an organism, typically referring to the Latin epithet of the genus element of the plant/animal scientific name.	Σ	0..1	CodeableConcept	The genus of an organism e.g. the Latin epithet of the plant/animal scientific name Binding: ?? (example): The genus of an organism, typically referring to the Latin epithet of the genus element of the plant/animal scientific name.
species	Σ	0..1	CodeableConcept	The species of an organism e.g. the Latin epithet of the species of the plant/animal Binding: ?? (example): A species of origin a substance raw material.	Σ	0..1	CodeableConcept	The species of an organism e.g. the Latin epithet of the species of the plant/animal Binding: ?? (example): A species of origin a substance raw material.
part	Σ	0..1	CodeableConcept	An anatomical origin of the source material within an organism Binding: ?? (example): An anatomical origin of the source material within an organism.	Σ	0..1	CodeableConcept	An anatomical origin of the source material within an organism Binding: ?? (example): An anatomical origin of the source material within an organism.
countryOfOrigin	Σ	0..*	CodeableConcept	The country or countries where the material is harvested Binding: ?? (required): Jurisdiction codes	Σ	0..*	CodeableConcept	The country or countries where the material is harvested Binding: ?? (required): Jurisdiction codes
Documentation for this format