# CP.4.2.2 Patient-Specific Medication Dosing and Warnings (Function) - HL7 Electronic Health Record System Functional Model, Release 2.1.1 v2.1.1

## Requirements: CP.4.2.2 Patient-Specific Medication Dosing and Warnings (Function) 

 
Render medication dosing and warnings related to a medication order based on patient-specific parameters. 



## Resource Content

```json
{
  "resourceType" : "Requirements",
  "id" : "EHRSFMR2-CP.4.2.2",
  "meta" : {
    "profile" : [
      "http://hl7.org/ehrs/uv/ehrsfmr2/StructureDefinition/FMFunction"
    ]
  },
  "language" : "en",
  "extension" : [
    {
      "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
      "valueCode" : "normative"
    },
    {
      "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-wg",
      "valueCode" : "ehr"
    }
  ],
  "url" : "http://hl7.org/ehrs/uv/ehrsfmr2/Requirements/EHRSFMR2-CP.4.2.2",
  "version" : "2.1.1",
  "name" : "CP_4_2_2_Patient_Specific_Medication_Dosing_and_Warnings",
  "title" : "CP.4.2.2 Patient-Specific Medication Dosing and Warnings (Function)",
  "status" : "active",
  "date" : "2025-12-13T09:06:06+00:00",
  "publisher" : "HL7 International / Electronic Health Records",
  "contact" : [
    {
      "telecom" : [
        {
          "system" : "url",
          "value" : "http://www.hl7.org/Special/committees/ehr"
        }
      ]
    }
  ],
  "description" : "Render medication dosing and warnings related to a medication order based on patient-specific parameters.",
  "jurisdiction" : [
    {
      "coding" : [
        {
          "system" : "http://unstats.un.org/unsd/methods/m49/m49.htm",
          "code" : "001",
          "display" : "World"
        }
      ]
    }
  ],
  "purpose" : "Provide parameter-based (e.g., weight, lean body mass, age, sensitivity, genomics, body surface area) medication dosing recommendations and warnings for simple medications and compounded medications at the time of order entry.",
  "statement" : [
    {
      "extension" : [
        {
          "url" : "http://hl7.org/ehrs/uv/ehrsfmr2/StructureDefinition/requirements-dependent",
          "valueBoolean" : false
        }
      ],
      "key" : "EHRSFMR2-CP.4.2.2-01",
      "label" : "CP.4.2.2#01",
      "conformance" : ["SHALL"],
      "conditionality" : false,
      "requirement" : "The system SHALL conform to function [CPS.4.2.2](Requirements-EHRSFMR2-CPS.4.2.2.html) (Support for Patient-Specific Dosing and Warnings) to determine potential adverse reactions and render alerts or notifications when new medications are ordered.",
      "derivedFrom" : "EHR-S_FM_R1.1 DC.1.7.1#17"
    },
    {
      "extension" : [
        {
          "url" : "http://hl7.org/ehrs/uv/ehrsfmr2/StructureDefinition/requirements-dependent",
          "valueBoolean" : false
        }
      ],
      "key" : "EHRSFMR2-CP.4.2.2-02",
      "label" : "CP.4.2.2#02",
      "conformance" : ["SHOULD"],
      "conditionality" : false,
      "requirement" : "The system SHOULD provide the ability to determine and render weight-specific dose suggestions and auto-populate (e.g., default) medication orders based on the suggested dosage.",
      "derivedFrom" : "EHR-S_FM_R1.1 DC.1.7.1#18"
    },
    {
      "extension" : [
        {
          "url" : "http://hl7.org/ehrs/uv/ehrsfmr2/StructureDefinition/requirements-dependent",
          "valueBoolean" : false
        }
      ],
      "key" : "EHRSFMR2-CP.4.2.2-03",
      "label" : "CP.4.2.2#03",
      "conformance" : ["MAY"],
      "conditionality" : false,
      "requirement" : "The system MAY provide the ability to capture alternative patient dosing weight(s) (e.g., ideal body weight or dry weight vs. actual patient weight) for the purpose of dose calculation."
    },
    {
      "extension" : [
        {
          "url" : "http://hl7.org/ehrs/uv/ehrsfmr2/StructureDefinition/requirements-dependent",
          "valueBoolean" : false
        }
      ],
      "key" : "EHRSFMR2-CP.4.2.2-04",
      "label" : "CP.4.2.2#04",
      "conformance" : ["SHOULD"],
      "conditionality" : true,
      "requirement" : "IF the system provides the ability to capture alternative patient dosing weight(s), THEN the system SHOULD provide the ability to determine and render alternative weight-specific dose recommendations and auto-populate medication orders based on the suggested dosage."
    },
    {
      "extension" : [
        {
          "url" : "http://hl7.org/ehrs/uv/ehrsfmr2/StructureDefinition/requirements-dependent",
          "valueBoolean" : false
        }
      ],
      "key" : "EHRSFMR2-CP.4.2.2-05",
      "label" : "CP.4.2.2#05",
      "conformance" : ["SHOULD"],
      "conditionality" : false,
      "requirement" : "The system SHOULD provide the ability to render patient-specific medication dosing recommendations based on the patient's age and weight/body surface area."
    },
    {
      "extension" : [
        {
          "url" : "http://hl7.org/ehrs/uv/ehrsfmr2/StructureDefinition/requirements-dependent",
          "valueBoolean" : false
        }
      ],
      "key" : "EHRSFMR2-CP.4.2.2-06",
      "label" : "CP.4.2.2#06",
      "conformance" : ["MAY"],
      "conditionality" : false,
      "requirement" : "The system MAY provide the ability to render patient-specific medication dosing recommendations based on previous patient experience (e.g., adverse reaction, type, and severity) with the same medication."
    },
    {
      "extension" : [
        {
          "url" : "http://hl7.org/ehrs/uv/ehrsfmr2/StructureDefinition/requirements-dependent",
          "valueBoolean" : false
        }
      ],
      "key" : "EHRSFMR2-CP.4.2.2-07",
      "label" : "CP.4.2.2#07",
      "conformance" : ["SHOULD"],
      "conditionality" : false,
      "requirement" : "The system SHOULD provide the ability to determine weight-based medication dosing when doses are based on the patient's weight (e.g., mg/kg)."
    },
    {
      "extension" : [
        {
          "url" : "http://hl7.org/ehrs/uv/ehrsfmr2/StructureDefinition/requirements-dependent",
          "valueBoolean" : false
        }
      ],
      "key" : "EHRSFMR2-CP.4.2.2-08",
      "label" : "CP.4.2.2#08",
      "conformance" : ["MAY"],
      "conditionality" : false,
      "requirement" : "The system MAY provide the ability to determine and render medication orders in which the weight-specific dose suggested employs a starting range with incremental changes toward a target range (e.g., a target therapeutic index)."
    },
    {
      "extension" : [
        {
          "url" : "http://hl7.org/ehrs/uv/ehrsfmr2/StructureDefinition/requirements-dependent",
          "valueBoolean" : false
        }
      ],
      "key" : "EHRSFMR2-CP.4.2.2-09",
      "label" : "CP.4.2.2#09",
      "conformance" : ["MAY"],
      "conditionality" : false,
      "requirement" : "The system MAY render a notification requesting the parameters (e.g., coefficients, exponents, formulas) required to calculate the body surface area."
    },
    {
      "extension" : [
        {
          "url" : "http://hl7.org/ehrs/uv/ehrsfmr2/StructureDefinition/requirements-dependent",
          "valueBoolean" : false
        }
      ],
      "key" : "EHRSFMR2-CP.4.2.2-10",
      "label" : "CP.4.2.2#10",
      "conformance" : ["MAY"],
      "conditionality" : false,
      "requirement" : "The system MAY provide the ability to determine and present dose ranges based on patient age."
    },
    {
      "extension" : [
        {
          "url" : "http://hl7.org/ehrs/uv/ehrsfmr2/StructureDefinition/requirements-dependent",
          "valueBoolean" : false
        }
      ],
      "key" : "EHRSFMR2-CP.4.2.2-11",
      "label" : "CP.4.2.2#11",
      "conformance" : ["MAY"],
      "conditionality" : false,
      "requirement" : "The system MAY provide the ability to manage complex medication orders that include dosing based on either physical status or laboratory values."
    },
    {
      "extension" : [
        {
          "url" : "http://hl7.org/ehrs/uv/ehrsfmr2/StructureDefinition/requirements-dependent",
          "valueBoolean" : false
        }
      ],
      "key" : "EHRSFMR2-CP.4.2.2-12",
      "label" : "CP.4.2.2#12",
      "conformance" : ["SHALL"],
      "conditionality" : false,
      "requirement" : "The system SHALL provide the ability to determine and present drug dosing based on custom compounded medication components."
    },
    {
      "extension" : [
        {
          "url" : "http://hl7.org/ehrs/uv/ehrsfmr2/StructureDefinition/requirements-dependent",
          "valueBoolean" : false
        }
      ],
      "key" : "EHRSFMR2-CP.4.2.2-13",
      "label" : "CP.4.2.2#13",
      "conformance" : ["SHOULD"],
      "conditionality" : false,
      "requirement" : "The system SHOULD provide the ability to manage medication orders with patient-specific dose calculations (e.g., by weight, body surface area or genotype)."
    }
  ]
}

```
