HL7 Electronic Health Record System Functional Model, Release 2.1.1
2.1.1 - Normative

HL7 Electronic Health Record System Functional Model, Release 2.1.1, published by HL7 International / Electronic Health Records. This guide is not an authorized publication; it is the continuous build for version 2.1.1 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/ehrsfm-ig/ and changes regularly. See the Directory of published versions

## : CP.4.2.2 Patient-Specific Medication Dosing and Warnings (Function)

Page standards status: Normative

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    <Requirements xmlns="http://hl7.org/fhir">
      <id value="EHRSFMR2-CP.4.2.2"/>
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        <status value="extensions"/>
        <div xml:lang="en" xmlns="http://www.w3.org/1999/xhtml" lang="en">

        <div id="description"><b>Description <a href="https://hl7.org/fhir/versions.html#std-process" title="Informative Content" class="informative-flag">I</a>:</b> <div><p>Provide parameter-based (e.g., weight, lean body mass, age, sensitivity, genomics, body surface area) medication dosing recommendations and warnings for simple medications and compounded medications at the time of order entry.</p>
    </div></div>

        <div id="requirements"><b>Criteria <a href="https://hl7.org/fhir/versions.html#std-process" title="Normative Content" class="normative-flag">N</a>:</b></div>

        <table id="statements" class="grid dict">

            <tr>
                <td style="padding-left: 4px;">
                CP.4.2.2#01
                </td>
                <td style="padding-left: 4px;">
                SHALL

                </td>
                <td style="padding-left: 4px;" class="requirement">
                    <div><p>The system SHALL conform to function <a href="Requirements-EHRSFMR2-CPS.4.2.2.html">CPS.4.2.2</a> (Support for Patient-Specific Dosing and Warnings) to determine potential adverse reactions and render alerts or notifications when new medications are ordered.</p>
    </div>

                </td>
            </tr>

            <tr>
                <td style="padding-left: 4px;">
                CP.4.2.2#02
                </td>
                <td style="padding-left: 4px;">
                SHOULD

                </td>
                <td style="padding-left: 4px;" class="requirement">
                    <div><p>The system SHOULD provide the ability to determine and render weight-specific dose suggestions and auto-populate (e.g., default) medication orders based on the suggested dosage.</p>
    </div>

                </td>
            </tr>

            <tr>
                <td style="padding-left: 4px;">
                CP.4.2.2#03
                </td>
                <td style="padding-left: 4px;">
                MAY

                </td>
                <td style="padding-left: 4px;" class="requirement">
                    <div><p>The system MAY provide the ability to capture alternative patient dosing weight(s) (e.g., ideal body weight or dry weight vs. actual patient weight) for the purpose of dose calculation.</p>
    </div>

                </td>
            </tr>

            <tr>
                <td style="padding-left: 4px;">
                CP.4.2.2#04
                </td>
                <td style="padding-left: 4px;">
                SHOULD

                <span style="border-radius: 999px;margin: 2px 2px;font-size: 10px;display: inline-block;padding: 3px 5px;letter-spacing: 0.5px;line-height: 1;white-space: nowrap;background-color: #f3e5ff;color: #7b1fa2;border: 1px solid #d1a3ff;">conditional</span>

                </td>
                <td style="padding-left: 4px;" class="requirement">
                    <div><p>IF the system provides the ability to capture alternative patient dosing weight(s), THEN the system SHOULD provide the ability to determine and render alternative weight-specific dose recommendations and auto-populate medication orders based on the suggested dosage.</p>
    </div>

                </td>
            </tr>

            <tr>
                <td style="padding-left: 4px;">
                CP.4.2.2#05
                </td>
                <td style="padding-left: 4px;">
                SHOULD

                </td>
                <td style="padding-left: 4px;" class="requirement">
                    <div><p>The system SHOULD provide the ability to render patient-specific medication dosing recommendations based on the patient's age and weight/body surface area.</p>
    </div>

                </td>
            </tr>

            <tr>
                <td style="padding-left: 4px;">
                CP.4.2.2#06
                </td>
                <td style="padding-left: 4px;">
                MAY

                </td>
                <td style="padding-left: 4px;" class="requirement">
                    <div><p>The system MAY provide the ability to render patient-specific medication dosing recommendations based on previous patient experience (e.g., adverse reaction, type, and severity) with the same medication.</p>
    </div>

                </td>
            </tr>

            <tr>
                <td style="padding-left: 4px;">
                CP.4.2.2#07
                </td>
                <td style="padding-left: 4px;">
                SHOULD

                </td>
                <td style="padding-left: 4px;" class="requirement">
                    <div><p>The system SHOULD provide the ability to determine weight-based medication dosing when doses are based on the patient's weight (e.g., mg/kg).</p>
    </div>

                </td>
            </tr>

            <tr>
                <td style="padding-left: 4px;">
                CP.4.2.2#08
                </td>
                <td style="padding-left: 4px;">
                MAY

                </td>
                <td style="padding-left: 4px;" class="requirement">
                    <div><p>The system MAY provide the ability to determine and render medication orders in which the weight-specific dose suggested employs a starting range with incremental changes toward a target range (e.g., a target therapeutic index).</p>
    </div>

                </td>
            </tr>

            <tr>
                <td style="padding-left: 4px;">
                CP.4.2.2#09
                </td>
                <td style="padding-left: 4px;">
                MAY

                </td>
                <td style="padding-left: 4px;" class="requirement">
                    <div><p>The system MAY render a notification requesting the parameters (e.g., coefficients, exponents, formulas) required to calculate the body surface area.</p>
    </div>

                </td>
            </tr>

            <tr>
                <td style="padding-left: 4px;">
                CP.4.2.2#10
                </td>
                <td style="padding-left: 4px;">
                MAY

                </td>
                <td style="padding-left: 4px;" class="requirement">
                    <div><p>The system MAY provide the ability to determine and present dose ranges based on patient age.</p>
    </div>

                </td>
            </tr>

            <tr>
                <td style="padding-left: 4px;">
                CP.4.2.2#11
                </td>
                <td style="padding-left: 4px;">
                MAY

                </td>
                <td style="padding-left: 4px;" class="requirement">
                    <div><p>The system MAY provide the ability to manage complex medication orders that include dosing based on either physical status or laboratory values.</p>
    </div>

                </td>
            </tr>

            <tr>
                <td style="padding-left: 4px;">
                CP.4.2.2#12
                </td>
                <td style="padding-left: 4px;">
                SHALL

                </td>
                <td style="padding-left: 4px;" class="requirement">
                    <div><p>The system SHALL provide the ability to determine and present drug dosing based on custom compounded medication components.</p>
    </div>

                </td>
            </tr>

            <tr>
                <td style="padding-left: 4px;">
                CP.4.2.2#13
                </td>
                <td style="padding-left: 4px;">
                SHOULD

                </td>
                <td style="padding-left: 4px;" class="requirement">
                    <div><p>The system SHOULD provide the ability to manage medication orders with patient-specific dose calculations (e.g., by weight, body surface area or genotype).</p>
    </div>

                </td>
            </tr>

        </table>
    </div>
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      <version value="2.1.1"/>
      <name value="CP_4_2_2_Patient_Specific_Medication_Dosing_and_Warnings"/>
      <title
             value="CP.4.2.2 Patient-Specific Medication Dosing and Warnings (Function)"/>
      <status value="active"/>
      <date value="2025-12-13T09:06:06+00:00"/>
      <publisher value="HL7 International / Electronic Health Records"/>
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      <description
                   value="Render medication dosing and warnings related to a medication order based on patient-specific parameters."/>
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        <coding>
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      <purpose
               value="Provide parameter-based (e.g., weight, lean body mass, age, sensitivity, genomics, body surface area) medication dosing recommendations and warnings for simple medications and compounded medications at the time of order entry."/>
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        <requirement
                     value="The system SHALL conform to function [CPS.4.2.2](Requirements-EHRSFMR2-CPS.4.2.2.html) (Support for Patient-Specific Dosing and Warnings) to determine potential adverse reactions and render alerts or notifications when new medications are ordered."/>
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    </Requirements>