HL7 Electronic Health Record System Functional Model, Release 2.1.1
2.1.1 - Normative

HL7 Electronic Health Record System Functional Model, Release 2.1.1, published by HL7 International / Electronic Health Records. This guide is not an authorized publication; it is the continuous build for version 2.1.1 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/ehrsfm-ig/ and changes regularly. See the Directory of published versions

## Requirements: CP.4.2.2 Patient-Specific Medication Dosing and Warnings (Function)

Official URL: http://hl7.org/ehrs/uv/ehrsfmr2/Requirements/EHRSFMR2-CP.4.2.2 | Version: 2.1.1
Standards status: Normative Active as of 2025-12-13 | Computable Name: CP_4_2_2_Patient_Specific_Medication_Dosing_and_Warnings

Render medication dosing and warnings related to a medication order based on patient-specific parameters.

Description I:

Provide parameter-based (e.g., weight, lean body mass, age, sensitivity, genomics, body surface area) medication dosing recommendations and warnings for simple medications and compounded medications at the time of order entry.

Criteria N:

CP.4.2.2#01 | SHALL | The system SHALL conform to function CPS.4.2.2 (Support for Patient-Specific Dosing and Warnings) to determine potential adverse reactions and render alerts or notifications when new medications are ordered.
CP.4.2.2#02 | SHOULD | The system SHOULD provide the ability to determine and render weight-specific dose suggestions and auto-populate (e.g., default) medication orders based on the suggested dosage.
CP.4.2.2#03 | MAY | The system MAY provide the ability to capture alternative patient dosing weight(s) (e.g., ideal body weight or dry weight vs. actual patient weight) for the purpose of dose calculation.
CP.4.2.2#04 | SHOULD conditional | IF the system provides the ability to capture alternative patient dosing weight(s), THEN the system SHOULD provide the ability to determine and render alternative weight-specific dose recommendations and auto-populate medication orders based on the suggested dosage.
CP.4.2.2#05 | SHOULD | The system SHOULD provide the ability to render patient-specific medication dosing recommendations based on the patient's age and weight/body surface area.
CP.4.2.2#06 | MAY | The system MAY provide the ability to render patient-specific medication dosing recommendations based on previous patient experience (e.g., adverse reaction, type, and severity) with the same medication.
CP.4.2.2#07 | SHOULD | The system SHOULD provide the ability to determine weight-based medication dosing when doses are based on the patient's weight (e.g., mg/kg).
CP.4.2.2#08 | MAY | The system MAY provide the ability to determine and render medication orders in which the weight-specific dose suggested employs a starting range with incremental changes toward a target range (e.g., a target therapeutic index).
CP.4.2.2#09 | MAY | The system MAY render a notification requesting the parameters (e.g., coefficients, exponents, formulas) required to calculate the body surface area.
CP.4.2.2#10 | MAY | The system MAY provide the ability to determine and present dose ranges based on patient age.
CP.4.2.2#11 | MAY | The system MAY provide the ability to manage complex medication orders that include dosing based on either physical status or laboratory values.
CP.4.2.2#12 | SHALL | The system SHALL provide the ability to determine and present drug dosing based on custom compounded medication components.
CP.4.2.2#13 | SHOULD | The system SHOULD provide the ability to manage medication orders with patient-specific dose calculations (e.g., by weight, body surface area or genotype).