Evidence Based Medicine on FHIR Implementation Guide
1.0.0-ballot3 - STU 1 Ballot 3 World

Evidence Based Medicine on FHIR Implementation Guide, published by HL7 International / Clinical Decision Support. This guide is not an authorized publication; it is the continuous build for version 1.0.0-ballot3 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/ebm/ and changes regularly. See the Directory of published versions

: Correlation of single nucleotide variant (SNV) and copy number variant (CNV) profiles with treatment response (NCT05327010)

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@prefix fhir: <http://hl7.org/fhir/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

# - resource -------------------------------------------------------------------

<http://hl7.org/fhir/EvidenceVariable/583777> a fhir:EvidenceVariable ;
  fhir:nodeRole fhir:treeRoot ;
  fhir:id [ fhir:v "583777"] ; # 
  fhir:meta [
     fhir:versionId [ fhir:v "2" ] ;
     fhir:lastUpdated [ fhir:v "2026-07-27T13:49:52.712Z"^^xsd:dateTime ] ;
     fhir:profile ( [
       fhir:v "http://hl7.org/fhir/uv/ebm/StructureDefinition/variable-definition"^^xsd:anyURI ;
       fhir:l <http://hl7.org/fhir/uv/ebm/StructureDefinition/variable-definition>
     ] )
  ] ; # 
  fhir:language [ fhir:v "en"] ; # 
  fhir:text [
     fhir:status [ fhir:v "extensions" ] ;
     fhir:div [ fhir:v "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: EvidenceVariable 583777</b></p><a name=\"583777\"> </a><a name=\"hc583777\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">version: 2; Last updated: 2026-07-27 13:49:52+0000</p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-variable-definition.html\">VariableDefinition</a></p></div><p><b>ArtifactPublicationStatus</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/cited-artifact-status-type active}\">Active</span></p><p><b>url</b>: <a href=\"https://fevir.net/resources/EvidenceVariable/583777\">https://fevir.net/resources/EvidenceVariable/583777</a></p><p><b>identifier</b>: FEvIR Object Identifier/583777, FEvIR Linking Identifier/NCT05327010-otherOutcome-1</p><p><b>name</b>: Correlation_of_single_nucleotide_variant_SNV_and_copy_number_variant_CNV_profiles_with_treatment_response_NCT05327010</p><p><b>title</b>: Correlation of single nucleotide variant (SNV) and copy number variant (CNV) profiles with treatment response (NCT05327010)</p><p><b>citeAs</b>: </p><div><p>Correlation of single nucleotide variant (SNV) and copy number variant (CNV) profiles with treatment response (NCT05327010) [Database Entry: FHIR EvidenceVariable Resource]. Contributors: Computable Publishing®: ClinicalTrials.gov-to-FEvIR Converter [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 583777. Revised 2026-07-27. Available at: https://fevir.net/resources/EvidenceVariable/583777. Computable resource at: https://fevir.net/resources/EvidenceVariable/583777#json.</p>\n</div><p><b>status</b>: Active</p><p><b>author</b>: Computable Publishing®: ClinicalTrials.gov-to-FEvIR Converter: </p><p><b>publisher</b>: Computable Publishing LLC</p><p><b>contact</b>: <a href=\"mailto:support@computablepublishing.com\">support@computablepublishing.com</a></p><p><b>description</b>: </p><div><p>Whole exome sequencing conducted on pre-treatment biopsy and at progression to correlate SNV and CNV profiles with treatment response.</p>\n</div><p><b>copyright</b>: </p><div><p>Copyright the Authors else Computable Publishing LLC. Noncommercial use permitted with CC BY-NC-SA 4.0 (https://creativecommons.org/licenses/by-nc-sa/4.0/). Commercial use permitted as agreed in Terms of Use (https://fevir.net/termsofuse).</p>\n</div><h3>Definitions</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Concept</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:\">Correlation of single nucleotide variant (SNV) and copy number variant (CNV) profiles with treatment response Whole exome sequencing conducted on pre-treatment biopsy and at progression to correlate SNV and CNV profiles with treatment response.</span></td></tr></table><p><b>handling</b>: <span title=\"Codes:{https://fevir.net/resources/CodeSystem/179423 evidence-variable-handling-not-specified}\">Evidence variable handling not specified</span></p><h3>Timings</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Text</b></td></tr><tr><td style=\"display: none\">*</td><td>Up to 2 years</td></tr></table></div>"^^rdf:XMLLiteral ]
  ] ; # 
  fhir:extension ( [
     fhir:url [
       fhir:v "http://hl7.org/fhir/uv/ebm/StructureDefinition/artifact-publication-status"^^xsd:anyURI ;
       fhir:l <http://hl7.org/fhir/uv/ebm/StructureDefinition/artifact-publication-status>
     ] ;
     fhir:value [
       a fhir:CodeableConcept ;
       fhir:coding ( [
         fhir:system [
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           fhir:l <http://terminology.hl7.org/CodeSystem/cited-artifact-status-type>
         ] ;
         fhir:code [ fhir:v "active" ] ;
         fhir:display [ fhir:v "Active" ]
       ] )
     ]
  ] ) ; # 
  fhir:url [
     fhir:v "https://fevir.net/resources/EvidenceVariable/583777"^^xsd:anyURI ;
     fhir:l <https://fevir.net/resources/EvidenceVariable/583777>
  ] ; # 
  fhir:identifier ( [
     fhir:type [
       fhir:coding ( [
         fhir:system [
           fhir:v "http://terminology.hl7.org/CodeSystem/v2-0203"^^xsd:anyURI ;
           fhir:l <http://terminology.hl7.org/CodeSystem/v2-0203>
         ] ;
         fhir:code [ fhir:v "ACSN" ] ;
         fhir:display [ fhir:v "Accession ID" ]
       ] ) ;
       fhir:text [ fhir:v "FEvIR Object Identifier" ]
     ] ;
     fhir:system [
       fhir:v "https://fevir.net/FOI"^^xsd:anyURI ;
       fhir:l <https://fevir.net/FOI>
     ] ;
     fhir:value [ fhir:v "583777" ] ;
     fhir:assigner [
       fhir:display [ fhir:v "Computable Publishing LLC" ]
     ]
  ] [
     fhir:type [
       fhir:text [ fhir:v "FEvIR Linking Identifier" ]
     ] ;
     fhir:system [
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     ] ;
     fhir:value [ fhir:v "NCT05327010-otherOutcome-1" ] ;
     fhir:assigner [
       fhir:display [ fhir:v "Computable Publishing LLC" ]
     ]
  ] ) ; # 
  fhir:name [ fhir:v "Correlation_of_single_nucleotide_variant_SNV_and_copy_number_variant_CNV_profiles_with_treatment_response_NCT05327010"] ; # 
  fhir:title [ fhir:v "Correlation of single nucleotide variant (SNV) and copy number variant (CNV) profiles with treatment response (NCT05327010)"] ; # 
  fhir:citeAs [ fhir:v "Correlation of single nucleotide variant (SNV) and copy number variant (CNV) profiles with treatment response (NCT05327010) [Database Entry: FHIR EvidenceVariable Resource]. Contributors: Computable Publishing®: ClinicalTrials.gov-to-FEvIR Converter [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 583777. Revised 2026-07-27. Available at: https://fevir.net/resources/EvidenceVariable/583777. Computable resource at: https://fevir.net/resources/EvidenceVariable/583777#json."] ; # 
  fhir:status [ fhir:v "active"] ; # 
  fhir:author ( [
     fhir:name [ fhir:v "Computable Publishing®: ClinicalTrials.gov-to-FEvIR Converter" ]
  ] ) ; # 
  fhir:publisher [ fhir:v "Computable Publishing LLC"] ; # 
  fhir:contact ( [
     fhir:telecom ( [
       fhir:system [ fhir:v "email" ] ;
       fhir:value [ fhir:v "support@computablepublishing.com" ]
     ] )
  ] ) ; # 
  fhir:description [ fhir:v "Whole exome sequencing conducted on pre-treatment biopsy and at progression to correlate SNV and CNV profiles with treatment response."] ; # 
  fhir:copyright [ fhir:v "Copyright the Authors else Computable Publishing LLC. Noncommercial use permitted with CC BY-NC-SA 4.0 (https://creativecommons.org/licenses/by-nc-sa/4.0/). Commercial use permitted as agreed in Terms of Use (https://fevir.net/termsofuse)."] ; # 
  fhir:definition [
     fhir:concept [
       fhir:text [ fhir:v "Correlation of single nucleotide variant (SNV) and copy number variant (CNV) profiles with treatment response Whole exome sequencing conducted on pre-treatment biopsy and at progression to correlate SNV and CNV profiles with treatment response." ]
     ]
  ] ; # 
  fhir:handling [
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       ] ;
       fhir:code [ fhir:v "evidence-variable-handling-not-specified" ] ;
       fhir:display [ fhir:v "Evidence variable handling not specified" ]
     ] )
  ] ; # 
  fhir:timing [
     fhir:text [ fhir:v "Up to 2 years" ]
  ] . #