Evidence Based Medicine on FHIR Implementation Guide
1.0.0-ballot3 - STU 1 Ballot 3 World

Evidence Based Medicine on FHIR Implementation Guide, published by HL7 International / Clinical Decision Support. This guide is not an authorized publication; it is the continuous build for version 1.0.0-ballot3 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/ebm/ and changes regularly. See the Directory of published versions

: VariableDefinition: NTproBNP

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{
  "resourceType" : "EvidenceVariable",
  "id" : "346298",
  "meta" : {
    "versionId" : "5",
    "lastUpdated" : "2025-03-10T17:19:52.217Z",
    "profile" : [
      🔗 "http://hl7.org/fhir/uv/ebm/StructureDefinition/variable-definition"
    ]
  },
  "language" : "en",
  "text" : {
    "status" : "extensions",
    "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: EvidenceVariable 346298</b></p><a name=\"346298\"> </a><a name=\"hc346298\"> </a><div style=\"display: inline-block; background-color: #fbffeb; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">version: 5; Last updated: 2025-03-10 17:19:52+0000</p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-variable-definition.html\">VariableDefinition</a></p></div><p><b>ArtifactPublicationStatus</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/cited-artifact-status-type active}\">Active</span></p><p><b>url</b>: <a href=\"EvidenceVariable-346298.html\">EvidenceVariable VariableDefinition: NTproBNP</a></p><p><b>identifier</b>: FEvIR Object Identifier/346298, <a href=\"http://terminology.hl7.org/7.5.0/NamingSystem-uri.html\" title=\"As defined by RFC 3986 (http://www.ietf.org/rfc/rfc3986.txt)(with many schemes defined in many RFCs). For OIDs and UUIDs, use the URN form (urn:oid:(note: lowercase) and urn:uuid:). See http://www.ietf.org/rfc/rfc3001.txt and http://www.ietf.org/rfc/rfc4122.txt \r\n\r\nThis oid is used as an identifier II.root to indicate the the extension is an absolute URI (technically, an IRI). Typically, this is used for OIDs and GUIDs. Note that when this OID is used with OIDs and GUIDs, the II.extension should start with urn:oid or urn:uuid: \r\n\r\nNote that this OID is created to aid with interconversion between CDA and FHIR - FHIR uses urn:ietf:rfc:3986 as equivalent to this OID. URIs as identifiers appear more commonly in FHIR.\r\n\r\nThis OID may also be used in CD.codeSystem.\">Uniform Resource Identifier (URI)</a>/urn:oid:2.16.840.1.113883.4.642.40.44.24.113</p><p><b>version</b>: 1.0.0-ballot3</p><p><b>name</b>: NTproBNP</p><p><b>title</b>: VariableDefinition: NTproBNP</p><p><b>citeAs</b>: </p><div><p>VariableDefinition: NTproBNP [Database Entry: FHIR EvidenceVariable Resource]. Contributors: Matthias Löbe [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 346298. Revised 2025-03-10. Available at: https://fevir.net/resources/EvidenceVariable/346298. Computable resource at: https://fevir.net/resources/EvidenceVariable/346298#json.</p>\n</div><p><b>status</b>: Active</p><p><b>date</b>: 2026-11-05 14:34:28+0000</p><p><b>author</b>: Matthias Löbe: </p><p><b>publisher</b>: HL7 International / Clinical Decision Support</p><p><b>contact</b>: HL7 International / Clinical Decision Support: <a href=\"http://www.hl7.org/Special/committees/dss\">http://www.hl7.org/Special/committees/dss</a></p><p><b>description</b>: </p><div><p>Numerical value of the NTproBNP measurement. (Example of VariableDefinition Profile for use with a Research Study Data Dictionary)</p>\n</div><p><b>copyright</b>: </p><div><p>https://creativecommons.org/licenses/by-nc-sa/4.0/</p>\n</div><h3>RelatesTos</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Target[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://terminology.hl7.org/CodeSystem/artifact-relationship-type part-of}\">Part Of</span></td><td><a href=\"Composition-342828.html\">Composition NT-proBNP Study Data Dictionary</a></td></tr></table><p><b>actual</b>: true</p><h3>Definitions</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Concept</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 414798009}\">Numerical value of the NTproBNP measurement</span></td></tr></table><h3>DefinitionModifiers</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:\">Substance being measured.</span></td><td><span title=\"Codes:{http://snomed.info/sct 414798009}\">N-terminal pro-B-type natriuretic peptide (substance)</span></td></tr></table><p><b>handling</b>: <span title=\"Codes:{https://fevir.net/sevco STATO:0000251}\">continuous variable</span></p><h3>Conditionals</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Expression</b></td></tr><tr><td style=\"display: none\">*</td><td>Always measured</td></tr></table><p><b>classifier</b>: <span title=\"Codes:\">clinical_data</span></p><h3>DataStorages</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Datatype</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://hl7.org/fhir/fhir-types decimal}\">decimal</span></td></tr></table></div>"
  },
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  ],
  "url" : "https://fevir.net/resources/EvidenceVariable/346298",
  "identifier" : [
    {
      "type" : {
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            "system" : "http://terminology.hl7.org/CodeSystem/v2-0203",
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        "text" : "FEvIR Object Identifier"
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  "version" : "1.0.0-ballot3",
  "name" : "NTproBNP",
  "title" : "VariableDefinition: NTproBNP",
  "citeAs" : "VariableDefinition: NTproBNP [Database Entry: FHIR EvidenceVariable Resource]. Contributors: Matthias Löbe [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 346298. Revised 2025-03-10. Available at: https://fevir.net/resources/EvidenceVariable/346298. Computable resource at: https://fevir.net/resources/EvidenceVariable/346298#json.",
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  "date" : "2026-11-05T14:34:28+00:00",
  "author" : [
    {
      "name" : "Matthias Löbe"
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  "publisher" : "HL7 International / Clinical Decision Support",
  "contact" : [
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  "description" : "Numerical value of the NTproBNP measurement. (Example of VariableDefinition Profile for use with a Research Study Data Dictionary)",
  "copyright" : "https://creativecommons.org/licenses/by-nc-sa/4.0/",
  "relatesTo" : [
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            "system" : "http://terminology.hl7.org/CodeSystem/artifact-relationship-type",
            "code" : "part-of",
            "display" : "Part Of"
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      "targetReference" : {
        🔗 "reference" : "Composition/342828",
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  "definition" : {
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      "coding" : [
        {
          "system" : "http://snomed.info/sct",
          "code" : "414798009",
          "display" : "N-terminal pro-B-type natriuretic peptide (substance)"
        }
      ],
      "text" : "Numerical value of the NTproBNP measurement"
    }
  },
  "definitionModifier" : [
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      "code" : {
        "text" : "Substance being measured."
      },
      "valueCodeableConcept" : {
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            "system" : "http://snomed.info/sct",
            "code" : "414798009",
            "display" : "N-terminal pro-B-type natriuretic peptide (substance)"
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        "display" : "continuous variable"
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  "conditional" : {
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  "dataStorage" : [
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      "datatype" : {
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}