Evidence Based Medicine on FHIR Implementation Guide
1.0.0-ballot3 - STU 1 Ballot 3 World

Evidence Based Medicine on FHIR Implementation Guide, published by HL7 International / Clinical Decision Support. This guide is not an authorized publication; it is the continuous build for version 1.0.0-ballot3 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/ebm/ and changes regularly. See the Directory of published versions

: Percentage of Participants With Clinical Recovery Within 14 Days After Randomization - for Control in Nigella Sativa for COVID-19 OSF Preprint

Raw json | Download

{
  "resourceType" : "Evidence",
  "id" : "6514",
  "meta" : {
    "versionId" : "1"
  },
  "language" : "en",
  "text" : {
    "status" : "extensions",
    "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: Evidence 6514</b></p><a name=\"6514\"> </a><a name=\"hc6514\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">version: 1</p></div><p><b>ArtifactPublicationStatus</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/cited-artifact-status-type active}\">Active</span></p><p><b>url</b>: <a href=\"https://fevir.net/resources/Evidence/6514\">https://fevir.net/resources/Evidence/6514</a></p><p><b>identifier</b>: FEvIR Object Identifier/6514</p><p><b>name</b>: OSFPreprint_PrimaryOutcomeMeasure_0_OG001</p><p><b>title</b>: Percentage of Participants With Clinical Recovery Within 14 Days After Randomization -  for Control in Nigella Sativa for COVID-19 OSF Preprint</p><p><b>status</b>: Active</p><p><b>date</b>: 2021-07-19 17:03:53+0000</p><p><b>author</b>: Brian S. Alper: </p><p><b>publisher</b>: Computable Publishing LLC</p><p><b>contact</b>: <a href=\"mailto:support@computablepublishing.com\">support@computablepublishing.com</a></p><p><b>copyright</b>: </p><div><p>https://creativecommons.org/licenses/by-nc-sa/4.0/</p>\n</div><p><b>description</b>: </p><div><p>This Evidence Resource is referenced in an example for the EBMonFHIR Implementation Guide.</p>\n</div><blockquote><p><b>variableDefinition</b></p><p><b>description</b>: </p><div><p>Control</p>\n</div><p><b>note</b>: </p><blockquote><div><p>control group within study population: Adult symptomatic patients with mild COVID-19 were recruited between May and August 2020 from King Abdulaziz University Hospital in Jeddah, Saudi Arabia.</p>\n</div></blockquote><p><b>variableRole</b>: Population</p><p><b>observed</b>: standard of care medications alone</p></blockquote><blockquote><p><b>variableDefinition</b></p><p><b>description</b>: </p><div><p>proportion of patients recovered (free of symptoms for 3 days) within 14 days after randomization</p>\n</div><p><b>variableRole</b>: Outcome</p><p><b>observed</b>: <a href=\"EvidenceVariable-5269.html\">EvidenceVariable Percentage of Participants With Clinical Recovery Within 14 Days After Randomization (NCT04401202)</a></p></blockquote><blockquote><p><b>statistic</b></p><p><b>description</b>: </p><div><p>There were 47 patients in the treatment group (NSO) and 47 patients in the control group. The proportion of patients recovered in the treatment group was significantly higher than the control group, 37 (79%) versus 21 (45%) (p=0.001).</p>\n</div><p><b>statisticType</b>: <span title=\"Codes:\">Count of Participants</span></p><p><b>quantity</b>: 21 Participants</p><h3>SampleSizes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>KnownDataCount</b></td></tr><tr><td style=\"display: none\">*</td><td>47</td></tr></table></blockquote></div>"
  },
  "extension" : [
    {
      "url" : "http://hl7.org/fhir/uv/ebm/StructureDefinition/artifact-publication-status",
      "valueCodeableConcept" : {
        "coding" : [
          {
            "system" : "http://terminology.hl7.org/CodeSystem/cited-artifact-status-type",
            "code" : "active",
            "display" : "Active"
          }
        ]
      }
    }
  ],
  "url" : "https://fevir.net/resources/Evidence/6514",
  "identifier" : [
    {
      "type" : {
        "coding" : [
          {
            "system" : "http://terminology.hl7.org/CodeSystem/v2-0203",
            "code" : "ACSN",
            "display" : "Accession ID"
          }
        ],
        "text" : "FEvIR Object Identifier"
      },
      "system" : "https://fevir.net/FOI",
      "value" : "6514",
      "assigner" : {
        "display" : "Computable Publishing LLC"
      }
    }
  ],
  "name" : "OSFPreprint_PrimaryOutcomeMeasure_0_OG001",
  "title" : "Percentage of Participants With Clinical Recovery Within 14 Days After Randomization -  for Control in Nigella Sativa for COVID-19 OSF Preprint",
  "status" : "active",
  "date" : "2021-07-19T17:03:53.324Z",
  "author" : [
    {
      "name" : "Brian S. Alper"
    }
  ],
  "publisher" : "Computable Publishing LLC",
  "contact" : [
    {
      "telecom" : [
        {
          "system" : "email",
          "value" : "support@computablepublishing.com"
        }
      ]
    }
  ],
  "copyright" : "https://creativecommons.org/licenses/by-nc-sa/4.0/",
  "description" : "This Evidence Resource is referenced in an example for the EBMonFHIR Implementation Guide.",
  "variableDefinition" : [
    {
      "description" : "Control",
      "note" : [
        {
          "text" : "control group within study population: Adult symptomatic patients with mild COVID-19 were recruited between May and August 2020 from King Abdulaziz University Hospital in Jeddah, Saudi Arabia."
        }
      ],
      "variableRole" : "population",
      "observed" : {
        "display" : "standard of care medications alone"
      }
    },
    {
      "description" : "proportion of patients recovered (free of symptoms for 3 days) within 14 days after randomization",
      "variableRole" : "outcome",
      "observed" : {
        🔗 "reference" : "EvidenceVariable/5269",
        "type" : "EvidenceVariable"
      }
    }
  ],
  "statistic" : [
    {
      "description" : "There were 47 patients in the treatment group (NSO) and 47 patients in the control group. The proportion of patients recovered in the treatment group was significantly higher than the control group, 37 (79%) versus 21 (45%) (p=0.001).",
      "statisticType" : {
        "text" : "Count of Participants"
      },
      "quantity" : {
        "value" : 21,
        "unit" : "Participants"
      },
      "sampleSize" : {
        "knownDataCount" : 47
      }
    }
  ]
}