Evidence Based Medicine on FHIR Implementation Guide
1.0.0-ballot3 - STU 1 ballot International flag

Evidence Based Medicine on FHIR Implementation Guide, published by HL7 International / Clinical Decision Support. This guide is not an authorized publication; it is the continuous build for version 1.0.0-ballot3 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/ebm/ and changes regularly. See the Directory of published versions

: NetEffectContribution for ComparativeEvidence: Bypass surgery effects on New onset depression in JAMA 2018 Norwegian cohort study

Raw xml | Download


<Evidence xmlns="http://hl7.org/fhir">
  <id value="179589"/>
  <meta>
    <versionId value="17"/>
    <lastUpdated value="2026-01-07T11:28:51.418Z"/>
    <profile
             value="http://hl7.org/fhir/uv/ebm/StructureDefinition/net-effect-contribution"/>
  </meta>
  <language value="en"/>
  <text>
    <status value="extensions"/>
    <div xmlns="http://www.w3.org/1999/xhtml" xml:lang="en" lang="en"><p class="res-header-id"><b>Generated Narrative: Evidence 179589</b></p><a name="179589"> </a><a name="hc179589"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">version: 17; Last updated: 2026-01-07 11:28:51+0000; Language: en</p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-net-effect-contribution.html">NetEffectContribution</a></p></div><p><b>url</b>: <a href="https://fevir.net/resources/Evidence/179589">https://fevir.net/resources/Evidence/179589</a></p><p><b>identifier</b>: FEvIR Object Identifier/179589</p><p><b>name</b>: NetEffectContribution_for_ComparativeEvidence_Bypass_surgery_effects_on_New_onset_depression_in_JAMA_2018_Norwegian_cohort_study</p><p><b>title</b>: NetEffectContribution for ComparativeEvidence: Bypass surgery effects on New onset depression in JAMA 2018 Norwegian cohort study</p><p><b>citeAs</b>: </p><div><p>NetEffectContribution for ComparativeEvidence: Bypass surgery effects on New onset depression in JAMA 2018 Norwegian cohort study [Database Entry: FHIR Evidence Resource]. Contributors: Computable Publishing: Net Effect Generator, Brian S. Alper, MD, MSPH [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 179589. Revised 2026-01-07. Available at: https://fevir.net/resources/Evidence/179589. Computable resource at: https://fevir.net/resources/Evidence/179589#json.</p>
</div><p><b>status</b>: Active</p><p><b>author</b>: Computable Publishing: Net Effect Generator: , Brian S. Alper, MD, MSPH: </p><p><b>publisher</b>: Computable Publishing LLC</p><p><b>contact</b>: <a href="mailto:support@computablepublishing.com">support@computablepublishing.com</a></p><p><b>copyright</b>: </p><div><p>https://creativecommons.org/licenses/by-nc-sa/4.0/</p>
</div><p><b>description</b>: </p><div><p>This Evidence Resource is referenced in an example for the EBMonFHIR Implementation Guide.</p>
</div><blockquote><p><b>variableDefinition</b></p><p><b>description</b>: </p><div><p>Cohort study with baseline data of exposures from November 2005 through July 2010 and follow-up data from 2006 until death or through December 2015 at a tertiary care outpatient center, Vestfold Hospital Trust, Norway. Consecutive treatment-seeking adult patients (n = 2109) with severe obesity assessed (221 patients excluded and 1888 patients included).</p>
</div><p><b>variableRole</b>: Population</p><p><b>observed</b>: <a href="Group-178427.html">StudyGroup: Severely Obese Adults 2018 Norwegian Cohort</a></p></blockquote><blockquote><p><b>variableDefinition</b></p><p><b>description</b>: </p><div><p>bariatric surgery vs. specialized medical treatment without bariatric surgery</p>
</div><p><b>variableRole</b>: Exposure</p><p><b>comparatorCategory</b>: no bariatric surgery</p><p><b>observed</b>: <a href="EvidenceVariable-172427.html">GroupAssignment: Bariatric Surgery vs. no bariatric surgery</a></p></blockquote><blockquote><p><b>variableDefinition</b></p><p><b>description</b>: </p><div><p>New onset depression</p>
</div><p><b>variableRole</b>: Outcome</p><p><b>observed</b>: <a href="EvidenceVariable-104118.html">OutcomeVariable: New onset depression</a></p></blockquote><blockquote><p><b>variableDefinition</b></p><p><b>RelativeOutcomeImportance</b>: <a href="ArtifactAssessment-423313.html">Outcome Importance Rating of DichotomousIntendedOutcome: New onset depression  for StudyEligibilityCriteria: Eligibility Criteria for Bariatric Surgery Randomized Trial (Diabetes Surgery Study)</a></p><p><b>variableRole</b>: Covariate</p><p><b>roleSubtype</b>: <span title="Codes:">Relative Value Multiplier</span></p><p><b>observed</b>: Relative Importance Multiplier</p></blockquote><blockquote><p><b>statistic</b></p><p><b>statisticType</b>: <span title="Codes:{https://fevir.net/sevco STATO:0000424}">risk difference</span></p><p><b>quantity</b>: -81.25</p><h3>AttributeEstimates</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Level</b></td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{https://fevir.net/sevco STATO:0000196}">confidence interval</span></td><td>0.95</td><td>-113.75--65</td></tr></table><h3>ModelCharacteristics</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:">Net effect contribution analysis</span></td></tr></table></blockquote></div>
  </text>
  <url value="https://fevir.net/resources/Evidence/179589"/>
  <identifier>
    <type>
      <coding>
        <system value="http://terminology.hl7.org/CodeSystem/v2-0203"/>
        <code value="ACSN"/>
        <display value="Accession ID"/>
      </coding>
      <text value="FEvIR Object Identifier"/>
    </type>
    <system value="https://fevir.net/FOI"/>
    <value value="179589"/>
    <assigner>
      <display value="Computable Publishing LLC"/>
    </assigner>
  </identifier>
  <name
        value="NetEffectContribution_for_ComparativeEvidence_Bypass_surgery_effects_on_New_onset_depression_in_JAMA_2018_Norwegian_cohort_study"/>
  <title
         value="NetEffectContribution for ComparativeEvidence: Bypass surgery effects on New onset depression in JAMA 2018 Norwegian cohort study"/>
  <citeAs
          value="NetEffectContribution for ComparativeEvidence: Bypass surgery effects on New onset depression in JAMA 2018 Norwegian cohort study [Database Entry: FHIR Evidence Resource]. Contributors: Computable Publishing: Net Effect Generator, Brian S. Alper, MD, MSPH [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 179589. Revised 2026-01-07. Available at: https://fevir.net/resources/Evidence/179589. Computable resource at: https://fevir.net/resources/Evidence/179589#json."/>
  <status value="active"/>
  <author>
    <name value="Computable Publishing: Net Effect Generator"/>
  </author>
  <author>
    <name value="Brian S. Alper, MD, MSPH"/>
  </author>
  <publisher value="Computable Publishing LLC"/>
  <contact>
    <telecom>
      <system value="email"/>
      <value value="support@computablepublishing.com"/>
    </telecom>
  </contact>
  <copyright value="https://creativecommons.org/licenses/by-nc-sa/4.0/"/>
  <description
               value="This Evidence Resource is referenced in an example for the EBMonFHIR Implementation Guide."/>
  <variableDefinition>
    <description
                 value="Cohort study with baseline data of exposures from November 2005 through July 2010 and follow-up data from 2006 until death or through December 2015 at a tertiary care outpatient center, Vestfold Hospital Trust, Norway. Consecutive treatment-seeking adult patients (n = 2109) with severe obesity assessed (221 patients excluded and 1888 patients included)."/>
    <variableRole value="population"/>
    <observed>🔗 
      <reference value="Group/178427"/>
      <type value="Group"/>
      <display
               value="StudyGroup: Severely Obese Adults 2018 Norwegian Cohort"/>
    </observed>
  </variableDefinition>
  <variableDefinition>
    <description
                 value="bariatric surgery vs. specialized medical treatment without bariatric surgery"/>
    <variableRole value="exposure"/>
    <comparatorCategory value="no bariatric surgery"/>
    <observed>🔗 
      <reference value="EvidenceVariable/172427"/>
      <type value="EvidenceVariable"/>
      <display
               value="GroupAssignment: Bariatric Surgery vs. no bariatric surgery"/>
    </observed>
  </variableDefinition>
  <variableDefinition>
    <description value="New onset depression"/>
    <variableRole value="outcome"/>
    <observed>🔗 
      <reference value="EvidenceVariable/104118"/>
      <type value="EvidenceVariable"/>
      <display value="OutcomeVariable: New onset depression"/>
    </observed>
  </variableDefinition>
  <variableDefinition>
    <extension
               url="http://hl7.org/fhir/uv/ebm/StructureDefinition/relative-outcome-importance">
      <valueReference>🔗 
        <reference value="ArtifactAssessment/423313"/>
        <type value="ArtifactAssessment"/>
        <display
                 value="Outcome Importance Rating of DichotomousIntendedOutcome: New onset depression  for StudyEligibilityCriteria: Eligibility Criteria for Bariatric Surgery Randomized Trial (Diabetes Surgery Study)"/>
      </valueReference>
    </extension>
    <variableRole value="covariate"/>
    <roleSubtype>
      <text value="Relative Value Multiplier"/>
    </roleSubtype>
    <observed>
      <display value="Relative Importance Multiplier"/>
    </observed>
  </variableDefinition>
  <statistic>
    <statisticType>
      <coding>
        <system value="https://fevir.net/sevco"/>
        <code value="STATO:0000424"/>
        <display value="risk difference"/>
      </coding>
    </statisticType>
    <quantity>
      <value value="-81.25"/>
    </quantity>
    <attributeEstimate>
      <type>
        <coding>
          <system value="https://fevir.net/sevco"/>
          <code value="STATO:0000196"/>
          <display value="confidence interval"/>
        </coding>
      </type>
      <level value="0.95"/>
      <range>
        <low>
          <value value="-113.75"/>
        </low>
        <high>
          <value value="-65"/>
        </high>
      </range>
    </attributeEstimate>
    <modelCharacteristic>
      <code>
        <text value="Net effect contribution analysis"/>
      </code>
    </modelCharacteristic>
  </statistic>
</Evidence>