Evidence Based Medicine on FHIR Implementation Guide
1.0.0-ballot3 - STU 1 ballot
Evidence Based Medicine on FHIR Implementation Guide
1.0.0-ballot3 - STU 1 ballot
Evidence Based Medicine on FHIR Implementation Guide, published by HL7 International / Clinical Decision Support. This guide is not an authorized publication; it is the continuous build for version 1.0.0-ballot3 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/ebm/ and changes regularly. See the Directory of published versions
| Page standards status: Informative |
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<div xml:lang="en" xmlns="http://www.w3.org/1999/xhtml" lang="en"><table><tbody><tr><th><div xml:lang="en" lang="en"><p>Outcome</p></div></th><th><div xml:lang="en" lang="en"><p>Sample Size</p></div></th><th><div xml:lang="en" lang="en"><p>Result Without Treatment</p></div></th><th><div xml:lang="en" lang="en"><p>Result With Treatment (Observed)</p></div></th><th><div xml:lang="en" lang="en"><p>Result With Treatment (Calculated)</p></div></th><th><div xml:lang="en" lang="en"><p>Effect Estimate</p></div></th><th><div xml:lang="en" lang="en"><p>Certainty of Evidence</p></div></th><th><div xml:lang="en" lang="en"><p>What this means</p></div></th></tr><tr><td><div xml:lang="en" lang="en"><p>Systolic blood pressure at 12 weeks</p></div></td><td><div xml:lang="en" lang="en"><p>62 participants, 60 analyzed, 53 without missing data</p></div></td><td><div xml:lang="en" lang="en"><div style="color: #AAAAAA;">[No summary statement.]</div></div></td><td><div xml:lang="en" lang="en"><div style="color: #AAAAAA;">[No summary statement.]</div></div></td><td><div xml:lang="en" lang="en"><div style="color: #AAAAAA;">[No summary statement.]</div></div></td><td><div xml:lang="en" lang="en"><p>difference in means -4.5 mm Hg (95% confidence interval -10.82 mm Hg to 1.32 mm Hg)</p></div></td><td><div xml:lang="en" lang="en"><div style="color: #AAAAAA;">[No summary statement.]</div></div></td><td><div xml:lang="en" lang="en"><div style="color: #AAAAAA;">[No summary statement.]</div></div></td></tr><tr><td><div xml:lang="en" lang="en"><p>Diastolic blood pressure at 12 weeks</p></div></td><td><div xml:lang="en" lang="en"><p>62 participants, 60 analyzed, 53 without missing data</p></div></td><td><div xml:lang="en" lang="en"><div style="color: #AAAAAA;">[No summary statement.]</div></div></td><td><div xml:lang="en" lang="en"><div style="color: #AAAAAA;">[No summary statement.]</div></div></td><td><div xml:lang="en" lang="en"><p>[Not a proportion.]</p></div></td><td><div xml:lang="en" lang="en"><p>difference in means -4.92 mm Hg (95% confidence interval -8.58 mm Hg to 0.27 mm Hg)</p></div></td><td><div xml:lang="en" lang="en"><div style="color: #AAAAAA;">[No summary statement.]</div></div></td><td><div xml:lang="en" lang="en"><div style="color: #AAAAAA;">[No summary statement.]</div></div></td></tr><tr><td><div xml:lang="en" lang="en"><p>Medication Adherence at 12 weeks</p></div></td><td><div xml:lang="en" lang="en"><p>62 participants, 53 without missing data</p></div></td><td><div xml:lang="en" lang="en"><p>70%</p></div></td><td><div xml:lang="en" lang="en"><p>65.6%</p></div></td><td><div xml:lang="en" lang="en"><p>46.33%</p></div></td><td><div xml:lang="en" lang="en"><p>odds ratio 0.37 (95% confidence interval 0.19 to 2.08)</p></div></td><td><div xml:lang="en" lang="en"><div style="color: #AAAAAA;">[No summary statement.]</div></div></td><td><div xml:lang="en" lang="en"><div style="color: #AAAAAA;">[No summary statement.]</div></div></td></tr><tr><td><div xml:lang="en" lang="en"><p>Hypertension Control at 12 weeks</p></div></td><td><div xml:lang="en" lang="en"><p>62 participants, 60 analyzed, 53 without missing data</p></div></td><td><div xml:lang="en" lang="en"><p>54.17%</p></div></td><td><div xml:lang="en" lang="en"><p>65.52%</p></div></td><td><div xml:lang="en" lang="en"><p>77.11%</p></div></td><td><div xml:lang="en" lang="en"><p>odds ratio 2.85 (95% confidence interval 0.94 to 8.59)</p></div></td><td><div xml:lang="en" lang="en"><div style="color: #AAAAAA;">[No summary statement.]</div></div></td><td><div xml:lang="en" lang="en"><div style="color: #AAAAAA;">[No summary statement.]</div></div></td></tr><tr><td><div xml:lang="en" lang="en"><p>Add-on Amlodipine at 6 weeks</p></div></td><td><div xml:lang="en" lang="en"><p>62 participants, 60 analyzed, 62 without missing data, 22 events</p></div></td><td><div xml:lang="en" lang="en"><p>53.33%</p></div></td><td><div xml:lang="en" lang="en"><p>18.75%</p></div></td><td><div xml:lang="en" lang="en"><p>51.25%</p></div></td><td><div xml:lang="en" lang="en"><p>odds ratio 0.92 (95% confidence interval 0.02 to 0.41)</p></div></td><td><div xml:lang="en" lang="en"><div style="color: #AAAAAA;">[No summary statement.]</div></div></td><td><div xml:lang="en" lang="en"><div style="color: #AAAAAA;">[No summary statement.]</div></div></td></tr><tr><td><div xml:lang="en" lang="en"><p>Adverse event free and hypertension control at 12 weeks</p></div></td><td><div xml:lang="en" lang="en"><p>62 participants, 53 analyzed, 53 without missing data, 13 events</p></div></td><td><div xml:lang="en" lang="en"><p>33.33%</p></div></td><td><div xml:lang="en" lang="en"><p>17.24%</p></div></td><td><div xml:lang="en" lang="en"><p>29.33%</p></div></td><td><div xml:lang="en" lang="en"><p>odds ratio 0.83 (95% confidence interval 0.22 to 3.16)</p></div></td><td><div xml:lang="en" lang="en"><div style="color: #AAAAAA;">[No summary statement.]</div></div></td><td><div xml:lang="en" lang="en"><div 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<div xmlns="http://www.w3.org/1999/xhtml"><p>mean 122.300 mm Hg (95% confidence interval 118.200 to 126.500 mm Hg)</p></div>
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<reference value="Evidence/375628"/>
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<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="sample-size"/>
<display value="Sample Size"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p>62 participants, 53 without missing data</p></div>
</text>
<entry>🔗
<reference value="Evidence/397481"/>
<type value="Evidence"/>
<display
value="Evidence for Results for Medication Adherence at 12 weeks in GroupAssignment: Quadpill vs. Candesartan"/>
</entry>
</section>
<section>
<title value="Result Without Treatment"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-comparator-alone"/>
<display value="Result with comparator alone"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p>70%</p></div>
</text>
<entry>🔗
<reference value="Evidence/379724"/>
<type value="Evidence"/>
<display
value="Evidence for Results for Medication Adherence at 12 weeks in QUARTET USA Trial Control Group"/>
</entry>
</section>
<section>
<title value="Result With Treatment--Observed"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-intervention-alone"/>
<display value="Result with intervention alone"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p>65.6%</p></div>
</text>
<entry>🔗
<reference value="Evidence/379723"/>
<type value="Evidence"/>
<display
value="Evidence for Results for Medication Adherence at 12 weeks in QUARTET USA Trial Quadpill group"/>
</entry>
</section>
<section>
<title value="Result With Treatment--Derived"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-intervention-alone-calculated"/>
<display value="Result with intervention alone (calculated)"/>
</coding>
<text
value="result with intervention with calculated value derived from the control group and effect estimate"/>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p>59.51%</p></div>
</text>
</section>
<section>
<title value="Effect Estimate"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-intervention-vs-comparator"/>
<display value="Result with intervention vs. comparator"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p>odds ratio 0.630 (95% confidence interval 0.190 to 2.080, p-value 0.444)</p></div>
</text>
<entry>🔗
<reference value="Evidence/397481"/>
<type value="Evidence"/>
<display
value="Evidence for Results for Medication Adherence at 12 weeks in GroupAssignment: Quadpill vs. Candesartan"/>
</entry>
</section>
<section>
<title value="Certainty of Evidence"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="certainty-of-evidence"/>
<display value="Certainty of Evidence"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p>[Certainty not specified.]</p></div>
</text>
<entry>🔗
<reference value="Evidence/397481"/>
<type value="Evidence"/>
<display
value="Evidence for Results for Medication Adherence at 12 weeks in GroupAssignment: Quadpill vs. Candesartan"/>
</entry>
</section>
<section>
<title value="Assertion"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="assertion"/>
<display value="Assertion"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p>[No assertion made.]</p></div>
</text>
<entry>🔗
<reference value="Evidence/397481"/>
<type value="Evidence"/>
<display
value="Evidence for Results for Medication Adherence at 12 weeks in GroupAssignment: Quadpill vs. Candesartan"/>
</entry>
</section>
</section>
<section>
<title value="Results for Hypertension Control at 12 weeks"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="summary-of-findings-entry-for-a-single-outcome"/>
<display value="Summary of findings entry for a single outcome"/>
</coding>
</code>
<focus>🔗
<reference value="EvidenceVariable/375202"/>
<type value="EvidenceVariable"/>
<display value="Hypertension Control at 12 weeks"/>
</focus>
<section>
<title value="Outcome Measure"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="outcome-measure"/>
<display value="Outcome Measure"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p>Results for Hypertension Control at 12 weeks</p></div>
</text>
<entry>🔗
<reference value="EvidenceVariable/375202"/>
<type value="EvidenceVariable"/>
<display value="Hypertension Control at 12 weeks"/>
</entry>
</section>
<section>
<title value="Sample Size"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="sample-size"/>
<display value="Sample Size"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p>62 participants, 60 analyzed, 53 without missing data</p></div>
</text>
<entry>🔗
<reference value="Evidence/397480"/>
<type value="Evidence"/>
<display
value="Evidence for Results for Hypertension Control at 12 weeks in GroupAssignment: Quadpill vs. Candesartan"/>
</entry>
</section>
<section>
<title value="Result Without Treatment"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-comparator-alone"/>
<display value="Result with comparator alone"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p>54.17%</p></div>
</text>
<entry>🔗
<reference value="Evidence/379737"/>
<type value="Evidence"/>
<display
value="Evidence for Results for Hypertension Control at 12 weeks in QUARTET USA Trial Control Group"/>
</entry>
</section>
<section>
<title value="Result With Treatment--Observed"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-intervention-alone"/>
<display value="Result with intervention alone"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p>65.52%</p></div>
</text>
<entry>🔗
<reference value="Evidence/379736"/>
<type value="Evidence"/>
<display
value="Evidence for Results for Hypertension Control at 12 weeks in QUARTET USA Trial Quadpill group"/>
</entry>
</section>
<section>
<title value="Result With Treatment--Derived"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-intervention-alone-calculated"/>
<display value="Result with intervention alone (calculated)"/>
</coding>
<text
value="result with intervention with calculated value derived from the control group and effect estimate"/>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p>77.11%</p></div>
</text>
</section>
<section>
<title value="Effect Estimate"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-intervention-vs-comparator"/>
<display value="Result with intervention vs. comparator"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p>odds ratio 2.850 (95% confidence interval 0.940 to 8.590, p-value 0.063)</p></div>
</text>
<entry>🔗
<reference value="Evidence/397480"/>
<type value="Evidence"/>
<display
value="Evidence for Results for Hypertension Control at 12 weeks in GroupAssignment: Quadpill vs. Candesartan"/>
</entry>
</section>
<section>
<title value="Certainty of Evidence"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="certainty-of-evidence"/>
<display value="Certainty of Evidence"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p>[Certainty not specified.]</p></div>
</text>
<entry>🔗
<reference value="Evidence/397480"/>
<type value="Evidence"/>
<display
value="Evidence for Results for Hypertension Control at 12 weeks in GroupAssignment: Quadpill vs. Candesartan"/>
</entry>
</section>
<section>
<title value="Assertion"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="assertion"/>
<display value="Assertion"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p>[No assertion made.]</p></div>
</text>
<entry>🔗
<reference value="Evidence/397480"/>
<type value="Evidence"/>
<display
value="Evidence for Results for Hypertension Control at 12 weeks in GroupAssignment: Quadpill vs. Candesartan"/>
</entry>
</section>
</section>
<section>
<title value="Results for Add-on Amlodipine at 6 weeks"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="summary-of-findings-entry-for-a-single-outcome"/>
<display value="Summary of findings entry for a single outcome"/>
</coding>
</code>
<focus>🔗
<reference value="EvidenceVariable/375203"/>
<type value="EvidenceVariable"/>
<display value="Add-on Amlodipine at 6 weeks"/>
</focus>
<section>
<title value="Outcome Measure"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="outcome-measure"/>
<display value="Outcome Measure"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p>Results for Add-on Amlodipine at 6 weeks</p></div>
</text>
<entry>🔗
<reference value="EvidenceVariable/375203"/>
<type value="EvidenceVariable"/>
<display value="Add-on Amlodipine at 6 weeks"/>
</entry>
</section>
<section>
<title value="Sample Size"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="sample-size"/>
<display value="Sample Size"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p>62 participants, 60 analyzed, 62 without missing data, 22 events</p></div>
</text>
<entry>🔗
<reference value="Evidence/397479"/>
<type value="Evidence"/>
<display
value="Evidence for Results for Add-on Amlodipine at 6 weeks in GroupAssignment: Quadpill vs. Candesartan"/>
</entry>
</section>
<section>
<title value="Result Without Treatment"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-comparator-alone"/>
<display value="Result with comparator alone"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p>53.33%</p></div>
</text>
<entry>🔗
<reference value="Evidence/379740"/>
<type value="Evidence"/>
<display
value="Evidence for Results for Add-on Amlodipine at 6 weeks in QUARTET USA Trial Control Group"/>
</entry>
</section>
<section>
<title value="Result With Treatment--Observed"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-intervention-alone"/>
<display value="Result with intervention alone"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p>18.75%</p></div>
</text>
<entry>🔗
<reference value="Evidence/379739"/>
<type value="Evidence"/>
<display
value="Evidence for Results for Add-on Amlodipine at 6 weeks in QUARTET USA Trial Quadpill group"/>
</entry>
</section>
<section>
<title value="Result With Treatment--Derived"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-intervention-alone-calculated"/>
<display value="Result with intervention alone (calculated)"/>
</coding>
<text
value="result with intervention with calculated value derived from the control group and effect estimate"/>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p>8.38%</p></div>
</text>
</section>
<section>
<title value="Effect Estimate"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-intervention-vs-comparator"/>
<display value="Result with intervention vs. comparator"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p>odds ratio 0.080 (95% confidence interval 0.020 to 0.410, p-value 0.003)</p></div>
</text>
<entry>🔗
<reference value="Evidence/397479"/>
<type value="Evidence"/>
<display
value="Evidence for Results for Add-on Amlodipine at 6 weeks in GroupAssignment: Quadpill vs. Candesartan"/>
</entry>
</section>
<section>
<title value="Certainty of Evidence"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="certainty-of-evidence"/>
<display value="Certainty of Evidence"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p>[Certainty not specified.]</p></div>
</text>
<entry>🔗
<reference value="Evidence/397479"/>
<type value="Evidence"/>
<display
value="Evidence for Results for Add-on Amlodipine at 6 weeks in GroupAssignment: Quadpill vs. Candesartan"/>
</entry>
</section>
<section>
<title value="Assertion"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="assertion"/>
<display value="Assertion"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p>[No assertion made.]</p></div>
</text>
<entry>🔗
<reference value="Evidence/397479"/>
<type value="Evidence"/>
<display
value="Evidence for Results for Add-on Amlodipine at 6 weeks in GroupAssignment: Quadpill vs. Candesartan"/>
</entry>
</section>
</section>
<section>
<title
value="Results for Adverse event free and hypertension control at 12 weeks"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="summary-of-findings-entry-for-a-single-outcome"/>
<display value="Summary of findings entry for a single outcome"/>
</coding>
</code>
<focus>🔗
<reference value="EvidenceVariable/375278"/>
<type value="EvidenceVariable"/>
<display
value="Adverse event free and hypertension control at 12 weeks"/>
</focus>
<section>
<title value="Outcome Measure"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="outcome-measure"/>
<display value="Outcome Measure"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p>Results for Adverse event free and hypertension control at 12 weeks</p></div>
</text>
<entry>🔗
<reference value="EvidenceVariable/375278"/>
<type value="EvidenceVariable"/>
<display
value="Adverse event free and hypertension control at 12 weeks"/>
</entry>
</section>
<section>
<title value="Sample Size"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="sample-size"/>
<display value="Sample Size"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p>62 participants, 53 analyzed, 53 without missing data, 13 events</p></div>
</text>
<entry>🔗
<reference value="Evidence/397478"/>
<type value="Evidence"/>
<display
value="Evidence for Results for Adverse event free and hypertension control at 12 weeks in GroupAssignment: Quadpill vs. Candesartan"/>
</entry>
</section>
<section>
<title value="Result Without Treatment"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-comparator-alone"/>
<display value="Result with comparator alone"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p>33.33%</p></div>
</text>
<entry>🔗
<reference value="Evidence/379743"/>
<type value="Evidence"/>
<display
value="Evidence for Results for Adverse event free and hypertension control at 12 weeks in QUARTET USA Trial Control Group"/>
</entry>
</section>
<section>
<title value="Result With Treatment--Observed"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-intervention-alone"/>
<display value="Result with intervention alone"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p>17.24%</p></div>
</text>
<entry>🔗
<reference value="Evidence/379742"/>
<type value="Evidence"/>
<display
value="Evidence for Results for Adverse event free and hypertension control at 12 weeks in QUARTET USA Trial Quadpill group"/>
</entry>
</section>
<section>
<title value="Result With Treatment--Derived"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-intervention-alone-calculated"/>
<display value="Result with intervention alone (calculated)"/>
</coding>
<text
value="result with intervention with calculated value derived from the control group and effect estimate"/>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p>29.33%</p></div>
</text>
</section>
<section>
<title value="Effect Estimate"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-intervention-vs-comparator"/>
<display value="Result with intervention vs. comparator"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p>odds ratio 0.830 (95% confidence interval 0.220 to 3.160, p-value 0.775)</p></div>
</text>
<entry>🔗
<reference value="Evidence/397478"/>
<type value="Evidence"/>
<display
value="Evidence for Results for Adverse event free and hypertension control at 12 weeks in GroupAssignment: Quadpill vs. Candesartan"/>
</entry>
</section>
<section>
<title value="Certainty of Evidence"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="certainty-of-evidence"/>
<display value="Certainty of Evidence"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p>[Certainty not specified.]</p></div>
</text>
<entry>🔗
<reference value="Evidence/397478"/>
<type value="Evidence"/>
<display
value="Evidence for Results for Adverse event free and hypertension control at 12 weeks in GroupAssignment: Quadpill vs. Candesartan"/>
</entry>
</section>
<section>
<title value="Assertion"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="assertion"/>
<display value="Assertion"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p>[No assertion made.]</p></div>
</text>
<entry>🔗
<reference value="Evidence/397478"/>
<type value="Evidence"/>
<display
value="Evidence for Results for Adverse event free and hypertension control at 12 weeks in GroupAssignment: Quadpill vs. Candesartan"/>
</entry>
</section>
</section>
</section>
</Composition>
IG © 2024+ HL7 International / Clinical Decision Support.
Package hl7.fhir.uv.ebm#1.0.0-ballot3 based on FHIR 6.0.0-ballot3.
Generated
2026-06-12
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