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Example of SummaryOfFindings Profile of Composition Resource.
EvidenceReportSubject: Clinical Outcomes for Effects of Bariatric Surgery
SummaryOfFindings: Bariatric Surgery Summary of Findings Example for GIN 2022
SummaryOfFindings: Bariatric Surgery Summary of Findings Example for GIN 2022 [Database Entry: FHIR Composition Resource]. Contributors: Brian S. Alper [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 104215. Revised 2025-02-25. Available at: https://fevir.net/resources/Composition/104215. Computable resource at: https://fevir.net/resources/Composition/104215.
Outcome
Sample size: # studies, # participants, # counted, # events
Result without bariatric surgery
Result with bariatric surgery
Result with intervention alone (calculated)
calculated value derived from the control group and effect estimate
Result with bariatric surgery (calculated)
Effect Estimate (Relative effect)
Certainty of finding (Quality of evidence)
What this means
Summary of findings entry for a single outcome
All-cause mortality
21 studies, 397002 participants
ComparativeEvidence: All-cause mortality effect of bariatric surgery in 2022 meta-analysis
5% (estimated); specific summary evidence not reported
ComparatorOnlyEvidence: All-cause mortality without bariatric surgery in 2022 meta-analysis
Not reported
Hazard Ratio 0.55 (95% confidence interval 0.49 to 0.62)
Low quality
The present systematic review and meta-analysis suggests that bariatric surgery is associated with reduced all-cause and CV mortality.
Nonfatal myocardial infarction or stroke
OutcomeVariable: Nonfatal myocardial infarction or stroke
1 study, 4,047 participants, 4,047 counted, 359 events
ComparativeEvidence: Bypass surgery effects on Myocardial infarction or stroke in Swedish Obese Subjects (SOS) study
188 out of 2,037 observed with percentage of: 9.2%
ComparatorOnlyEvidence: Myocardial infarction or stroke without bariatric surgery (Control Group) in Swedish Obese Subjects (SOS) study
171 out of 2,010 observed with percentage of: 8.5%
6.2%
Hazard Ratio 0.67 (95% CI 0.54 to 0.83)
Compared with usual care, bariatric surgery was associated with reduced number of cardiovascular deaths and lower incidence of cardiovascular events in obese adults.
Remission of diabetes
1 study, 1,888 participants, 1,888 counted
ComparativeEvidence: Bypass surgery effects on Remission of diabetes in JAMA 2018 Norwegian cohort study
141 out of 956 observed with percentage of: 14.8%
ComparatorOnlyEvidence: Remission of diabetes without bariatric surgery (Control Group) in JAMA 2018 Norwegian cohort study
536 out of 932 observed with percentage of: 57.5%
57.7%
Relative Risk 3.9 (95% CI 2.8 to 5.4)
Moderate quality
Compared with specialized medical treatment, bariatric surgery appears to induce remission of diabetes.
New onset depression
ComparativeEvidence: Bypass surgery effects on New onset depression in JAMA 2018 Norwegian cohort study
62 out of 956 observed with percentage of: 6.5%
ComparatorOnlyEvidence: New onset depression without bariatric surgery (Control Group) in JAMA 2018 Norwegian cohort study
83 out of 932 observed with percentage of: 8.9%
9.75%
Relative Risk 1.5 (95% CI 1.4 to 1.7)
Compared with specialized medical treatment, bariatric surgery may slightly increase the incidence of depression.
Treatment with opioids
ComparativeEvidence: Bypass surgery effects on Treatment with opioids in JAMA 2018 Norwegian cohort study
151 out of 956 observed with percentage of: 15.8%
ComparatorOnlyEvidence: Treatment with opioids without bariatric surgery (Control Group) in JAMA 2018 Norwegian cohort study
181 out of 932 observed with percentage of: 19.4%
20.5%
Relative Risk 1.3 (95% CI 1.2 to 1.4)
Compared with specialized medical treatment, bariatric surgery may slightly increase the use of opioids.
OutcomeVariable: Additional GI surgical procedure
Additional GI surgical procedure
StudyOutcomeEvidence: Bypass surgery effects on Additional GI surgical procedure in JAMA 2018 Norwegian cohort study
148 out of 956 observed with percentage of: 15.5%
ComparatorOnlyEvidence: Additional GI surgical procedure without bariatric surgery (Control Group) in JAMA 2018 Norwegian cohort study
292 out of 932 observed with percentage of: 31.3%
31%
ComparativeEvidence: Bypass surgery effects on Additional GI surgical procedure in JAMA 2018 Norwegian cohort study
Relative Risk 2.0 (95% CI 1.7 to 2.4)
Compared with specialized medical treatment, bariatric surgery appears to increase the rate of additional gastrointestinal surgical procedures.