@prefix fhir: <http://hl7.org/fhir/> .
@prefix loinc: <https://loinc.org/rdf/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix sct: <http://snomed.info/id/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

# - resource -------------------------------------------------------------------

<http://hl7.org/fhir/uv/ebm/Group/279347> a fhir:Group ;
  fhir:nodeRole fhir:treeRoot ;
  fhir:id [ fhir:v "279347"] ; # 
  fhir:meta [
     fhir:versionId [ fhir:v "15" ] ;
     fhir:lastUpdated [ fhir:v "2025-03-15T21:00:37.685Z"^^xsd:dateTime ] ;
     fhir:profile ( [
       fhir:v "http://hl7.org/fhir/uv/ebm/StructureDefinition/conceptual-cohort-definition"^^xsd:anyURI ;
       fhir:l <http://hl7.org/fhir/uv/ebm/StructureDefinition/conceptual-cohort-definition>
     ] )
  ] ; # 
  fhir:language [ fhir:v "en"] ; # 
  fhir:text [
     fhir:status [ fhir:v "empty" ] ;
     fhir:div [ fhir:v "<div xml:lang=\"en\" xmlns=\"http://www.w3.org/1999/xhtml\" lang=\"en\">[No data.]</div>"^^rdf:XMLLiteral ]
  ] ; # 
  fhir:extension ( [
     fhir:url [
       fhir:v "http://hl7.org/fhir/StructureDefinition/artifact-author"^^xsd:anyURI ;
       fhir:l <http://hl7.org/fhir/StructureDefinition/artifact-author>
     ] ;
     fhir:value [
       a fhir:ContactDetail ;
       fhir:name [ fhir:v "Brian S. Alper" ]
     ]
  ] [
     fhir:url [
       fhir:v "http://hl7.org/fhir/uv/ebm/StructureDefinition/cite-as"^^xsd:anyURI ;
       fhir:l <http://hl7.org/fhir/uv/ebm/StructureDefinition/cite-as>
     ] ;
     fhir:value [
       a fhir:Markdown ;
       fhir:v "ConceptualCohortDefinition: T1DM-specific criteria [Database Entry: FHIR Group Resource]. Contributors: Brian S. Alper [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 279347. Revised 2024-11-16. Available at: https://fevir.net/resources/Group/279347. Computable resource at: https://fevir.net/resources/Group/279347#json."
     ]
  ] [
     fhir:url [
       fhir:v "http://hl7.org/fhir/uv/ebm/StructureDefinition/artifact-publication-status"^^xsd:anyURI ;
       fhir:l <http://hl7.org/fhir/uv/ebm/StructureDefinition/artifact-publication-status>
     ] ;
     fhir:value [
       a fhir:CodeableConcept ;
       fhir:coding ( [
         fhir:system [
           fhir:v "http://terminology.hl7.org/CodeSystem/cited-artifact-status-type"^^xsd:anyURI ;
           fhir:l <http://terminology.hl7.org/CodeSystem/cited-artifact-status-type>
         ] ;
         fhir:code [ fhir:v "active" ] ;
         fhir:display [ fhir:v "Active" ]
       ] )
     ]
  ] ) ; # 
  fhir:url [
     fhir:v "https://fevir.net/resources/Group/279347"^^xsd:anyURI ;
     fhir:l <https://fevir.net/resources/Group/279347>
  ] ; # 
  fhir:identifier ( [
     fhir:type [
       fhir:coding ( [
         fhir:system [
           fhir:v "http://terminology.hl7.org/CodeSystem/v2-0203"^^xsd:anyURI ;
           fhir:l <http://terminology.hl7.org/CodeSystem/v2-0203>
         ] ;
         fhir:code [ fhir:v "ACSN" ] ;
         fhir:display [ fhir:v "Accession ID" ]
       ] ) ;
       fhir:text [ fhir:v "FEvIR Object Identifier" ]
     ] ;
     fhir:system [
       fhir:v "https://fevir.net/FOI"^^xsd:anyURI ;
       fhir:l <https://fevir.net/FOI>
     ] ;
     fhir:value [ fhir:v "279347" ] ;
     fhir:assigner [
       fhir:display [ fhir:v "Computable Publishing LLC" ]
     ]
  ] ) ; # 
  fhir:title [ fhir:v "ConceptualCohortDefinition: T1DM-specific criteria"] ; # 
  fhir:status [ fhir:v "active"] ; # 
  fhir:publisher [ fhir:v "Computable Publishing LLC"] ; # 
  fhir:contact ( [
     fhir:telecom ( [
       fhir:system [ fhir:v "email" ] ;
       fhir:value [ fhir:v "support@computablepublishing.com" ]
     ] )
  ] ) ; # 
  fhir:description [ fhir:v "i. Diagnosis of T1DM based on the World Health Organization (WHO) diagnostic criteria\nii. have been on the following daily insulin therapy for at least 1 year\n..1) multiple daily injection of long-acting insulin analog (either insulin glargine [U-100 or U-300] or insulin degludec [U-100]) and rapid-acting insulin analog (insulin lispro, insulin aspart, or insulin glulisine), or...2) continuous subcutaneous insulin infusion (CSII)\niii. are between 18 and 64 years old at the time of informed consent\niv. have a body mass index of 18.5 to 30.0 kg/m2 at the time of screening"] ; # 
  fhir:copyright [ fhir:v "https://creativecommons.org/licenses/by-nc-sa/4.0/"] ; # 
  fhir:membership [ fhir:v "conceptual"] ; # 
  fhir:combinationMethod [ fhir:v "all-of"] ; # 
  fhir:characteristic ( [
     fhir:code [
       fhir:coding ( [
         a sct:64572001 ;
         fhir:system [
           fhir:v "http://snomed.info/sct"^^xsd:anyURI ;
           fhir:l <http://snomed.info/sct>
         ] ;
         fhir:code [ fhir:v "64572001" ] ;
         fhir:display [ fhir:v "Disease (disorder)" ]
       ] )
     ] ;
     fhir:value [
       a fhir:CodeableConcept ;
       fhir:coding ( [
         a sct:46635009 ;
         fhir:system [
           fhir:v "http://snomed.info/sct"^^xsd:anyURI ;
           fhir:l <http://snomed.info/sct>
         ] ;
         fhir:code [ fhir:v "46635009" ] ;
         fhir:display [ fhir:v "Diabetes mellitus type 1 (disorder)" ]
       ] )
     ] ;
     fhir:exclude [ fhir:v false ] ;
     fhir:description [ fhir:v "Diagnosis of T1DM based on the World Health Organization (WHO) diagnostic criteria" ] ;
     fhir:method ( [
       fhir:text [ fhir:v "based on the World Health Organization (WHO) diagnostic criteria" ]
     ] )
  ] [
     fhir:code [
       fhir:text [ fhir:v "Medication exposure" ]
     ] ;
     fhir:value [
       a fhir:CodeableConcept ;
       fhir:text [ fhir:v "Insulin therapy with multiple daily injection of long-acting insulin analog (either insulin glargine [U-100 or U-300] or insulin degludec [U-100]) and rapid-acting insulin analog (insulin lispro, insulin aspart, or insulin glulisine), or continuous subcutaneous insulin infusion (CSII)" ]
     ] ;
     fhir:exclude [ fhir:v false ] ;
     fhir:description [ fhir:v "Have been on the following daily insulin therapy for at least 1 year\n..1) multiple daily injection of long-acting insulin analog (either insulin glargine [U-100 or U-300] or insulin degludec [U-100]) and rapid-acting insulin analog (insulin lispro, insulin aspart, or insulin glulisine), or...2) continuous subcutaneous insulin infusion (CSII)" ] ;
     fhir:duration [
       a fhir:Duration ;
       fhir:value [ fhir:v "1"^^xsd:decimal ] ;
       fhir:comparator [ fhir:v ">=" ] ;
       fhir:unit [ fhir:v "years" ] ;
       fhir:system [
         fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ;
         fhir:l <http://unitsofmeasure.org>
       ] ;
       fhir:code [ fhir:v "a" ]
     ]
  ] [
     fhir:code [
       fhir:coding ( [
         a sct:397669002 ;
         fhir:system [
           fhir:v "http://snomed.info/sct"^^xsd:anyURI ;
           fhir:l <http://snomed.info/sct>
         ] ;
         fhir:code [ fhir:v "397669002" ] ;
         fhir:display [ fhir:v "Age" ]
       ] )
     ] ;
     fhir:value [
       a fhir:Range ;
       fhir:low [
         fhir:value [ fhir:v "18"^^xsd:decimal ] ;
         fhir:unit [ fhir:v "years" ] ;
         fhir:system [
           fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ;
           fhir:l <http://unitsofmeasure.org>
         ] ;
         fhir:code [ fhir:v "a" ]
       ] ;
       fhir:high [
         fhir:value [ fhir:v "64"^^xsd:decimal ] ;
         fhir:unit [ fhir:v "years" ] ;
         fhir:system [
           fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ;
           fhir:l <http://unitsofmeasure.org>
         ] ;
         fhir:code [ fhir:v "a" ]
       ]
     ] ;
     fhir:exclude [ fhir:v false ] ;
     fhir:description [ fhir:v "Are between 18 and 64 years old at the time of informed consent" ] ;
     fhir:timing ( [
       fhir:contextCode [
         fhir:coding ( [
           a sct:182771004 ;
           fhir:system [
             fhir:v "http://snomed.info/sct"^^xsd:anyURI ;
             fhir:l <http://snomed.info/sct>
           ] ;
           fhir:code [ fhir:v "182771004" ] ;
           fhir:display [ fhir:v "Informed consent for procedure" ]
         ] )
       ] ;
       fhir:offset [
         a fhir:Duration ;
         fhir:value [ fhir:v "0"^^xsd:decimal ]
       ]
     ] )
  ] [
     fhir:code [
       fhir:coding ( [
         a loinc:39156-5 ;
         fhir:system [
           fhir:v "http://loinc.org"^^xsd:anyURI ;
           fhir:l <http://loinc.org>
         ] ;
         fhir:code [ fhir:v "39156-5" ] ;
         fhir:display [ fhir:v "Body mass index (BMI) [Ratio]" ]
       ] )
     ] ;
     fhir:value [
       a fhir:Range ;
       fhir:low [
         fhir:value [ fhir:v 18.5 ] ;
         fhir:unit [ fhir:v "kilogram per square meter (kg/m2)" ] ;
         fhir:system [
           fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ;
           fhir:l <http://unitsofmeasure.org>
         ] ;
         fhir:code [ fhir:v "kg/m2" ]
       ] ;
       fhir:high [
         fhir:value [ fhir:v "30"^^xsd:decimal ] ;
         fhir:unit [ fhir:v "kilogram per square meter (kg/m2)" ] ;
         fhir:system [
           fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ;
           fhir:l <http://unitsofmeasure.org>
         ] ;
         fhir:code [ fhir:v "kg/m2" ]
       ]
     ] ;
     fhir:exclude [ fhir:v false ] ;
     fhir:description [ fhir:v "Have a body mass index of 18.5 to 30.0 kg/m2 at the time of screening" ] ;
     fhir:timing ( [
       fhir:contextCode [
         fhir:text [ fhir:v "screening" ]
       ] ;
       fhir:offset [
         a fhir:Duration ;
         fhir:value [ fhir:v "0"^^xsd:decimal ]
       ]
     ] )
  ] ) . # 

# -------------------------------------------------------------------------------------

