Evidence Based Medicine on FHIR Implementation Guide
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Evidence Based Medicine on FHIR Implementation Guide, published by HL7 International / Clinical Decision Support. This guide is not an authorized publication; it is the continuous build for version 1.0.0-ballot3 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/ebm/ and changes regularly. See the Directory of published versions

: NetEffectContribution for ComparativeEvidence: Bypass surgery effects on Myocardial infarction or stroke in Swedish Obese Subjects (SOS) study

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@prefix fhir: <http://hl7.org/fhir/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

# - resource -------------------------------------------------------------------

<http://hl7.org/fhir/Evidence/179587> a fhir:Evidence ;
  fhir:nodeRole fhir:treeRoot ;
  fhir:id [ fhir:v "179587"] ; # 
  fhir:meta [
     fhir:versionId [ fhir:v "13" ] ;
     fhir:lastUpdated [ fhir:v "2026-01-07T11:26:17.820Z"^^xsd:dateTime ] ;
     fhir:profile ( [
       fhir:v "http://hl7.org/fhir/uv/ebm/StructureDefinition/net-effect-contribution"^^xsd:anyURI ;
       fhir:l <http://hl7.org/fhir/uv/ebm/StructureDefinition/net-effect-contribution>
     ] )
  ] ; # 
  fhir:language [ fhir:v "en"] ; # 
  fhir:text [
     fhir:status [ fhir:v "extensions" ] ;
     fhir:div [ fhir:v "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: Evidence 179587</b></p><a name=\"179587\"> </a><a name=\"hc179587\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">version: 13; Last updated: 2026-01-07 11:26:17+0000</p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-net-effect-contribution.html\">NetEffectContribution</a></p></div><p><b>url</b>: <a href=\"https://fevir.net/resources/Evidence/179587\">https://fevir.net/resources/Evidence/179587</a></p><p><b>identifier</b>: FEvIR Object Identifier/179587</p><p><b>name</b>: NetEffectContribution_for_ComparativeEvidence_Bypass_surgery_effects_on_Myocardial_infarction_or_stroke_in_Swedish_Obese_Subjects_SOS_study</p><p><b>title</b>: NetEffectContribution for ComparativeEvidence: Bypass surgery effects on Myocardial infarction or stroke in Swedish Obese Subjects (SOS) study</p><p><b>citeAs</b>: </p><div><p>NetEffectContribution for ComparativeEvidence: Bypass surgery effects on Myocardial infarction or stroke in Swedish Obese Subjects (SOS) study [Database Entry: FHIR Evidence Resource]. Contributors: Computable Publishing: Net Effect Generator, Brian S. Alper, MD, MSPH [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 179587. Revised 2026-01-07. Available at: https://fevir.net/resources/Evidence/179587. Computable resource at: https://fevir.net/resources/Evidence/179587#json.</p>\n</div><p><b>status</b>: Active</p><p><b>author</b>: Computable Publishing: Net Effect Generator: , Brian S. Alper, MD, MSPH: </p><p><b>publisher</b>: Computable Publishing LLC</p><p><b>contact</b>: <a href=\"mailto:support@computablepublishing.com\">support@computablepublishing.com</a></p><p><b>copyright</b>: </p><div><p>https://creativecommons.org/licenses/by-nc-sa/4.0/</p>\n</div><p><b>description</b>: </p><div><p>This Evidence Resource is referenced in an example for the EBMonFHIR Implementation Guide.</p>\n</div><blockquote><p><b>variableDefinition</b></p><p><b>description</b>: </p><div><p>Inclusion criteria were age 37 to 60 years and a body mass index of at least 34 in men and at least 38 in women.  All in Sweden.</p>\n</div><p><b>variableRole</b>: Population</p></blockquote><blockquote><p><b>variableDefinition</b></p><p><b>description</b>: </p><div><p>bariatric surgery vs. usual care without bariatric surgery</p>\n</div><p><b>variableRole</b>: Exposure</p><p><b>comparatorCategory</b>: no bariatric surgery</p><p><b>intended</b>: <a href=\"EvidenceVariable-172427.html\">GroupAssignment: Bariatric Surgery vs. no bariatric surgery</a></p></blockquote><blockquote><p><b>variableDefinition</b></p><p><b>description</b>: </p><div><p>nonfatal myocardial infarction or stroke</p>\n</div><p><b>variableRole</b>: Outcome</p><p><b>observed</b>: <a href=\"EvidenceVariable-104097.html\">OutcomeVariable: Nonfatal myocardial infarction or stroke</a></p></blockquote><blockquote><p><b>variableDefinition</b></p><p><b>RelativeOutcomeImportance</b>: <a href=\"ArtifactAssessment-423310.html\">Outcome Importance Rating of DichotomousIntendedOutcome: Nonfatal myocardial infarction or stroke  for StudyEligibilityCriteria: Eligibility Criteria for Bariatric Surgery Randomized Trial (Diabetes Surgery Study)</a></p><p><b>variableRole</b>: Covariate</p><p><b>roleSubtype</b>: <span title=\"Codes:\">Relative Value Multiplier</span></p><p><b>observed</b>: Relative Importance Multiplier</p></blockquote><blockquote><p><b>statistic</b></p><p><b>statisticType</b>: <span title=\"Codes:{https://fevir.net/sevco STATO:0000424}\">risk difference</span></p><p><b>quantity</b>: 151.8</p><h3>AttributeEstimates</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Level</b></td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{https://fevir.net/sevco STATO:0000196}\">confidence interval</span></td><td>0.95</td><td>78.2-211.6</td></tr></table><h3>ModelCharacteristics</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:\">Net effect contribution analysis</span></td></tr></table></blockquote></div>"^^rdf:XMLLiteral ]
  ] ; # 
  fhir:url [
     fhir:v "https://fevir.net/resources/Evidence/179587"^^xsd:anyURI ;
     fhir:l <https://fevir.net/resources/Evidence/179587>
  ] ; # 
  fhir:identifier ( [
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       fhir:coding ( [
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         ] ;
         fhir:code [ fhir:v "ACSN" ] ;
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       ] ) ;
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     ] ;
     fhir:value [ fhir:v "179587" ] ;
     fhir:assigner [
       fhir:display [ fhir:v "Computable Publishing LLC" ]
     ]
  ] ) ; # 
  fhir:name [ fhir:v "NetEffectContribution_for_ComparativeEvidence_Bypass_surgery_effects_on_Myocardial_infarction_or_stroke_in_Swedish_Obese_Subjects_SOS_study"] ; # 
  fhir:title [ fhir:v "NetEffectContribution for ComparativeEvidence: Bypass surgery effects on Myocardial infarction or stroke in Swedish Obese Subjects (SOS) study"] ; # 
  fhir:citeAs [ fhir:v "NetEffectContribution for ComparativeEvidence: Bypass surgery effects on Myocardial infarction or stroke in Swedish Obese Subjects (SOS) study [Database Entry: FHIR Evidence Resource]. Contributors: Computable Publishing: Net Effect Generator, Brian S. Alper, MD, MSPH [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 179587. Revised 2026-01-07. Available at: https://fevir.net/resources/Evidence/179587. Computable resource at: https://fevir.net/resources/Evidence/179587#json."] ; # 
  fhir:status [ fhir:v "active"] ; # 
  fhir:author ( [
     fhir:name [ fhir:v "Computable Publishing: Net Effect Generator" ]
  ] [
     fhir:name [ fhir:v "Brian S. Alper, MD, MSPH" ]
  ] ) ; # 
  fhir:publisher [ fhir:v "Computable Publishing LLC"] ; # 
  fhir:contact ( [
     fhir:telecom ( [
       fhir:system [ fhir:v "email" ] ;
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  ] ) ; # 
  fhir:copyright [ fhir:v "https://creativecommons.org/licenses/by-nc-sa/4.0/"] ; # 
  fhir:description [ fhir:v "This Evidence Resource is referenced in an example for the EBMonFHIR Implementation Guide."] ; # 
  fhir:variableDefinition ( [
     fhir:description [ fhir:v "Inclusion criteria were age 37 to 60 years and a body mass index of at least 34 in men and at least 38 in women.  All in Sweden." ] ;
     fhir:variableRole [ fhir:v "population" ]
  ] [
     fhir:description [ fhir:v "bariatric surgery vs. usual care without bariatric surgery" ] ;
     fhir:variableRole [ fhir:v "exposure" ] ;
     fhir:comparatorCategory [ fhir:v "no bariatric surgery" ] ;
     fhir:intended [
       fhir:l <http://hl7.org/fhir/EvidenceVariable/172427> ;
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       fhir:display [ fhir:v "GroupAssignment: Bariatric Surgery vs. no bariatric surgery" ]
     ]
  ] [
     fhir:description [ fhir:v "nonfatal myocardial infarction or stroke" ] ;
     fhir:variableRole [ fhir:v "outcome" ] ;
     fhir:observed [
       fhir:l <http://hl7.org/fhir/EvidenceVariable/104097> ;
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       fhir:type [
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         fhir:l fhir:EvidenceVariable
       ] ;
       fhir:display [ fhir:v "OutcomeVariable: Nonfatal myocardial infarction or stroke" ]
     ]
  ] [
     fhir:extension ( [
       fhir:url [
         fhir:v "http://hl7.org/fhir/uv/ebm/StructureDefinition/relative-outcome-importance"^^xsd:anyURI ;
         fhir:l <http://hl7.org/fhir/uv/ebm/StructureDefinition/relative-outcome-importance>
       ] ;
       fhir:value [
         a fhir:Reference ;
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         fhir:type [
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           fhir:l fhir:ArtifactAssessment
         ] ;
         fhir:display [ fhir:v "Outcome Importance Rating of DichotomousIntendedOutcome: Nonfatal myocardial infarction or stroke  for StudyEligibilityCriteria: Eligibility Criteria for Bariatric Surgery Randomized Trial (Diabetes Surgery Study)" ]
       ]
     ] ) ;
     fhir:variableRole [ fhir:v "covariate" ] ;
     fhir:roleSubtype [
       fhir:text [ fhir:v "Relative Value Multiplier" ]
     ] ;
     fhir:observed [
       fhir:display [ fhir:v "Relative Importance Multiplier" ]
     ]
  ] ) ; # 
  fhir:statistic ( [
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         fhir:code [ fhir:v "STATO:0000424" ] ;
         fhir:display [ fhir:v "risk difference" ]
       ] )
     ] ;
     fhir:quantity [
       fhir:value [ fhir:v 151.8 ]
     ] ;
     fhir:attributeEstimate ( [
       fhir:type [
         fhir:coding ( [
           fhir:system [
             fhir:v "https://fevir.net/sevco"^^xsd:anyURI ;
             fhir:l <https://fevir.net/sevco>
           ] ;
           fhir:code [ fhir:v "STATO:0000196" ] ;
           fhir:display [ fhir:v "confidence interval" ]
         ] )
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       fhir:level [ fhir:v 0.95 ] ;
       fhir:range [
         fhir:low [
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         fhir:high [
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       ]
     ] ) ;
     fhir:modelCharacteristic ( [
       fhir:code [
         fhir:text [ fhir:v "Net effect contribution analysis" ]
       ]
     ] )
  ] ) . # 

<http://hl7.org/fhir/EvidenceVariable/172427> a fhir:EvidenceVariable .

<http://hl7.org/fhir/EvidenceVariable/104097> a fhir:EvidenceVariable .

<http://hl7.org/fhir/ArtifactAssessment/423310> a fhir:ArtifactAssessment .