http://hl7.org/fhir/uv/ebm/Composition/236537
type: Composition
node role: treeRoot
id:
  v: 236537
meta:
  version id:
    v: 78
  last updated:
    v: 2025-10-21T14:50:13.423Z
  profile:
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    l: summary-of-findings
language:
  v: en
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Composition 236537 version: 78; Last updated: 2025-10-21 14:50:13+0000; Language: en Profile: SummaryOfFindings url: https://fevir.net/resources/Composition/236537 identifier: FEvIR Object Identifier/236537, FEvIR Linking Identifier/MAGIC-5288-j1Wqrn-summary-of-findings-85390-85789 status: Final type: Summary of Findings date: 2025-10-21 14:50:13+0000 author: Qiukui Hao title: SummaryOfFindings: GLP-1 RA vs. Standard care in Adults with type 2 diabetes with moderate CV risk custodian: Computable Publishing LLC relatesTo type: Part Of target: MAGICapp Conversion Report: SGLT2 inhibitors and GLP-1 RA for type 2 diabetes (Identifier: FEvIR Linking Identifier/MAGIC-5288-j1Wqrn-conversion-report) relatesTo type: Part Of target: ComparativeEvidenceSynthesisReport: GLP-1 RA vs. Standard care in Adults with type 2 diabetes with moderate CV risk relatesTo type: Cite As target: SummaryOfFindings: GLP-1 RA vs. Standard care in Adults with type 2 diabetes with moderate CV risk [Database Entry: FHIR Composition Resource]. Contributors: Qiukui Hao [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 236537. Revised 2025-10-21. Available at: https://fevir.net/resources/Composition/236537. Computable resource at: https://fevir.net/resources/Composition/236537#json.
url:
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identifier:
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        l: v2-0203
      code:
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      display:
        v: Accession ID
    text:
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  system:
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    l: FOI
  value:
    v: 236537
  assigner:
    display:
      v: Computable Publishing LLC
identifier:
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    text:
      v: FEvIR Linking Identifier
  system:
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    l: FLI
  value:
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  assigner:
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status:
  v: final
type:
  coding:
    system:
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      l: https://fevir.net/resources/CodeSystem/179423
    code:
      v: SummaryOfFindings
    display:
      v: SummaryOfFindings
  text:
    v: Summary of Findings
date:
  v: 2025-10-21T14:50:13.423Z
author:
  display:
    v: Qiukui Hao
title:
  v: SummaryOfFindings: GLP-1 RA vs. Standard care in Adults with type 2 diabetes with moderate CV risk
custodian:
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  reference:
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  type:
    v: Organization
    l: Organization
  display:
    v: Computable Publishing LLC
relates to:
  type:
    v: part-of
  target: Reference
    type:
      v: Composition
      l: Composition
    identifier:
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        l: FLI
      value:
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    display:
      v: MAGICapp Conversion Report: SGLT2 inhibitors and GLP-1 RA for type 2 diabetes
relates to:
  type:
    v: part-of
  target: Reference
    l: http://hl7.org/fhir/uv/ebm/Composition/236538
    reference:
      v: Composition/236538
    type:
      v: Composition
      l: Composition
    identifier:
      system:
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        l: FLI
      value:
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    display:
      v: ComparativeEvidenceSynthesisReport: GLP-1 RA vs. Standard care in Adults with type 2 diabetes with moderate CV risk
relates to:
  type:
    v: cite-as
  target: Markdown
    v: SummaryOfFindings: GLP-1 RA vs. Standard care in Adults with type 2 diabetes with moderate CV risk [Database Entry: FHIR Composition Resource]. Contributors: Qiukui Hao [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 236537. Revised 2025-10-21. Available at: https://fevir.net/resources/Composition/236537. Computable resource at: https://fevir.net/resources/Composition/236537#json.
section:
  title:
    v: Column Headers
  code:
    coding:
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        l: https://fevir.net/resources/CodeSystem/179423
      code:
        v: column-headers
      display:
        v: Column Headers
  text:
    status:
      v: empty
    div:
      v: [No narrative text.]
  section:
    title:
      v: Outcome Measure
    text:
      status:
        v: generated
      div:
        v: Outcome
  section:
    title:
      v: Sample Size
    text:
      status:
        v: generated
      div:
        v: Sample Size
  section:
    title:
      v: Result Without Treatment
    text:
      status:
        v: generated
      div:
        v: Result Without Treatment
  section:
    title:
      v: Result With Treatment--Observed
    text:
      status:
        v: generated
      div:
        v: Result With Treatment (Observed)
  section:
    title:
      v: Result With Treatment--Derived
    code:
      text:
        v: result with intervention with calculated value derived from the control group and effect estimate
    text:
      status:
        v: generated
      div:
        v: Result With Treatment (Calculated)
  section:
    title:
      v: Effect Estimate
    text:
      status:
        v: generated
      div:
        v: Effect Estimate
  section:
    title:
      v: Certainty of Evidence
    text:
      status:
        v: generated
      div:
        v: Certainty of Evidence
  section:
    title:
      v: Assertion
    text:
      status:
        v: generated

v: FEvIR Linking Identifier

v: Computable Publishing LLC

v: FEvIR Linking Identifier

v: Computable Publishing LLC

v: outcome-measure

v: Outcome Measure

v: sample-size

v: Sample Size

v: result-with-comparator-alone

v: Result with comparator alone

v: result-with-intervention-alone

v: Result with intervention alone

v: result-with-intervention-alone-calculated

v: Result with intervention alone (calculated)

v: result-with-intervention-vs-comparator

v: Result with intervention vs. comparator

v: certainty-of-evidence

v: Certainty of Evidence

v: assertion

v: Assertion

v: What this means

title:
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code:
  coding:
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text:
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section:
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  code:
    coding:
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        l: https://fevir.net/resources/CodeSystem/179423
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    display:
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  section:
    title:
      v: Outcome
    text:
      status:
        v: generated
      div:
        v: OutcomeDefinition: All-cause mortality
    entry:
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      reference:
        v: EvidenceVariable/236539
      type:
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        l: EvidenceVariable
      display:
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  section:
    title:
      v: Sample Size
    text:
      status:
        v: generated
      div:
        v: 34 studies, 69035 participants
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      reference:
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      type:
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        l: Evidence
      display:
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  section:
    title:
      v: Result Without Treatment
    text:
      status:
        v: generated
      div:
        v: 12%
    entry:
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      reference:
        v: Evidence/236541
      type:
        v: Evidence
        l: Evidence
      display:
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  section:
    title:
      v: Result With Treatment--Observed
    text:
      status:
        v: generated
      div:
        v: 10.7%
    entry:
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      reference:
        v: Evidence/293872
      type:
        v: Evidence
        l: Evidence
      display:
        v: MAGIC-derived InterventionOnlyEvidence: All-cause mortality in GLP-1 RA Group in Adults with type 2 diabetes with moderate CV risk
  section:
    title:
      v: Result With Treatment--Derived
    code:
      text:
        v: result with intervention with calculated value derived from the control group and effect estimate
    text:
      status:
        v: generated
      div:
        v: 10.71%
    entry:
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      reference:
        v: Evidence/236541
      type:
        v: Evidence
        l: Evidence
      display:
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      reference:
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      type:
        v: Evidence
        l: Evidence
      display:
        v: MAGIC-derived Evidence: All-cause mortality with GLP-1 RA vs. Standard care in Adults with type 2 diabetes with moderate CV risk
  section:
    title:
      v: Effect Estimate
    text:
      status:
        v: generated
      div:
        v: -1.29% (-1.83% to -0.64%)
    entry:
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      reference:
        v: Evidence/236540
      type:
        v: Evidence
        l: Evidence
      display:
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  section:
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    text:
      status:
        v: generated
      div:
        v: Moderate certainty -- Due to serious imprecision
    entry:
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      reference:
        v: Evidence/236540
      type:
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      display:
        v: MAGIC-derived Evidence: All-cause mortality with GLP-1 RA vs. Standard care in Adults with type 2 diabetes with moderate CV risk
  section:
    title:
      v: Assertion
    text:
      status:
        v: generated
      div:
        v: GLP-1 receptor agonists probably reduce the risk of death compared with standard care.
    entry:
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      reference:
        v: Evidence/236540
      type:
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      display:
        v: MAGIC-derived Evidence: All-cause mortality with GLP-1 RA vs. Standard care in Adults with type 2 diabetes with moderate CV risk
section:
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text:
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display:
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v: sample-size

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text:
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display:
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v: result-with-comparator-alone

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text:
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display:
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v: result-with-intervention-alone

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text:
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display:
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v: result-with-intervention-alone-calculated

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display:
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text:
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display:
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v: result-with-intervention-vs-comparator

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text:
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v: MAGIC-5288-j1Wqrn-dichotomous-outcome-313876-comparative-evidence

display:
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v: certainty-of-evidence

v: Certainty of Evidence

text:
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v: MAGIC-5288-j1Wqrn-dichotomous-outcome-313876-comparative-evidence

display:
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v: assertion

v: Assertion

text:
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display:
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reference:
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display:
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title:
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code:
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    code:
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    display:
      v: Outcome Measure
text:
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entry:
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  reference:
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    value:
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    assigner:
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  display:
    v: OutcomeDefinition: Cardiovascular mortality

title:
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code:
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    code:
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    display:
      v: Sample Size
text:
  status:
    v: generated
  div:
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entry:
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  reference:
    v: Evidence/236543
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    value:
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    assigner:
      display:
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  display:
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title:
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code:
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    code:
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    display:
      v: Result with comparator alone
text:
  status:
    v: generated
  div:
    v: 7.9%
entry:
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    v: Evidence/236544
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    value:
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    assigner:
      display:
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  display:
    v: MAGIC-derived ComparatorOnlyEvidence: Cardiovascular mortality in Standard care Group in Adults with type 2 diabetes with moderate CV risk

title:
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code:
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    display:
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text:
  status:
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entry:
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    assigner:
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  display:
    v: MAGIC-derived InterventionOnlyEvidence: Cardiovascular mortality in GLP-1 RA Group in Adults with type 2 diabetes with moderate CV risk

title:
  v: Result With Treatment--Derived
code:
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    display:
      v: Result with intervention alone (calculated)
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text:
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    v: 7.02%
entry:
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    system:
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    value:
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    assigner:
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        v: Computable Publishing LLC
  display:
    v: MAGIC-derived ComparatorOnlyEvidence: Cardiovascular mortality in Standard care Group in Adults with type 2 diabetes with moderate CV risk
entry:
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  reference:
    v: Evidence/236543
  type:
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    type:
      text:
        v: FEvIR Linking Identifier
    system:
      v: https://fevir.net/FLI
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    value:
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    assigner:
      display:
        v: Computable Publishing LLC
  display:
    v: MAGIC-derived Evidence: Cardiovascular mortality with GLP-1 RA vs. Standard care in Adults with type 2 diabetes with moderate CV risk

title:
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code:
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      l: https://fevir.net/resources/CodeSystem/179423
    code:
      v: result-with-intervention-vs-comparator
    display:
      v: Result with intervention vs. comparator
text:
  status:
    v: generated
  div:
    v: -0.88% (-1.48% to -0.29%)
entry:
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  reference:
    v: Evidence/236543
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    v: Evidence
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    type:
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        v: FEvIR Linking Identifier
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    assigner:
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  display:
    v: MAGIC-derived Evidence: Cardiovascular mortality with GLP-1 RA vs. Standard care in Adults with type 2 diabetes with moderate CV risk

title:
  v: Certainty of Evidence
code:
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    display:
      v: Certainty of Evidence
text:
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    v: Moderate certainty -- Due to serious imprecision
entry:
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title:
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code:
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    code:
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text:
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    v: generated
  div:
    v: GLP-1 receptor agonists probably reduce the risk of cardiovascular death compared with standard care.
entry:
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    v: Evidence/236543
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    v: Evidence
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    value:
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        v: Computable Publishing LLC
  display:
    v: MAGIC-derived Evidence: Cardiovascular mortality with GLP-1 RA vs. Standard care in Adults with type 2 diabetes with moderate CV risk

title:
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code:
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    code:
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      v: Summary of findings entry for a single outcome
focus:
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  identifier:
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title:
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      v: Evidence/293875
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v: FEvIR Linking Identifier

v: Computable Publishing LLC

v: FEvIR Linking Identifier

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v: FEvIR Linking Identifier

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title:
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display:
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title:
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title:
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title:
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      l: Evidence
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        v: Result with intervention alone (calculated)
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        v: https://fevir.net/FLI
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v: FEvIR Linking Identifier

v: Computable Publishing LLC

v: FEvIR Linking Identifier

v: Computable Publishing LLC

v: FEvIR Linking Identifier

v: Computable Publishing LLC

v: FEvIR Linking Identifier

v: Computable Publishing LLC

v: FEvIR Linking Identifier

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display:
  v: Computable Publishing LLC

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title:
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title:
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title:
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    type:
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section:
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    display:
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section:
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  text:
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      v: Evidence/236559
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      l: Evidence
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section:
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      v: Evidence/293878
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      v: Evidence
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      code:
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        v: Result with intervention alone (calculated)
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  text:
    status:
      v: generated
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      v: Evidence/236559
    type:
      v: Evidence
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    display:
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      v: Evidence/236558
    type:
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        v: https://fevir.net/FLI
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v: FEvIR Linking Identifier

v: Computable Publishing LLC

v: FEvIR Linking Identifier

v: Computable Publishing LLC

v: FEvIR Linking Identifier

v: Computable Publishing LLC

v: FEvIR Linking Identifier

v: Computable Publishing LLC

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v: FEvIR Linking Identifier

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display:
  v: Computable Publishing LLC

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title:
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title:
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title:
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  display:
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title:
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    assigner:
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        v: Sample Size
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      system:
        v: https://fevir.net/FLI
        l: FLI
      value:
        v: MAGIC-5288-j1Wqrn-dichotomous-outcome-313883-comparative-evidence
    display:
      v: MAGIC-derived Evidence: Severe gastrointestinal events with GLP-1 RA vs. Standard care in Adults with type 2 diabetes with moderate CV risk
section:
  title:
    v: Result Without Treatment
  code:
    coding:
      system:
        v: https://fevir.net/resources/CodeSystem/179423
        l: https://fevir.net/resources/CodeSystem/179423
      code:
        v: result-with-comparator-alone
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        v: Result with comparator alone
  text:
    status:
      v: generated
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      v: 4.4%
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      v: Evidence/236562
    type:
      v: Evidence
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    identifier:
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section:
  title:
    v: Result With Treatment--Observed
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    coding:
      system:
        v: https://fevir.net/resources/CodeSystem/179423
        l: https://fevir.net/resources/CodeSystem/179423
      code:
        v: result-with-intervention-alone
      display:
        v: Result with intervention alone
  text:
    status:
      v: generated
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      v: 10.2%
  entry:
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      v: Evidence/293879
    type:
      v: Evidence
      l: Evidence
    identifier:
      system:
        v: https://fevir.net/FLI
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      value:
        v: MAGIC-5288-j1Wqrn-dichotomous-outcome-313883-intervention-only-evidence
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      v: MAGIC-derived InterventionOnlyEvidence: Severe gastrointestinal events in GLP-1 RA Group in Adults with type 2 diabetes with moderate CV risk
section:
  title:
    v: Result With Treatment--Derived
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    coding:
      system:
        v: https://fevir.net/resources/CodeSystem/179423
        l: https://fevir.net/resources/CodeSystem/179423
      code:
        v: result-with-intervention-alone-calculated
      display:
        v: Result with intervention alone (calculated)
    text:
      v: result with intervention with calculated value derived from the control group and effect estimate
  text:
    status:
      v: generated
    div:
      v: 10.17%
  entry:
    l: http://hl7.org/fhir/uv/ebm/Evidence/236562
    reference:
      v: Evidence/236562
    type:
      v: Evidence
      l: Evidence
    identifier:
      system:
        v: https://fevir.net/FLI
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      value:
        v: MAGIC-5288-j1Wqrn-dichotomous-outcome-313883-comparator-only-evidence
    display:
      v: MAGIC-derived ComparatorOnlyEvidence: Severe gastrointestinal events in Standard care Group in Adults with type 2 diabetes with moderate CV risk
  entry:
    l: http://hl7.org/fhir/uv/ebm/Evidence/236561
    reference:
      v: Evidence/236561
    type:
      v: Evidence
      l: Evidence
    identifier:
      system:
        v: https://fevir.net/FLI
        l: FLI

v: FEvIR Linking Identifier

v: Computable Publishing LLC

v: FEvIR Linking Identifier

v: Computable Publishing LLC

v: FEvIR Linking Identifier

v: Computable Publishing LLC

v: FEvIR Linking Identifier

v: Computable Publishing LLC

v: FEvIR Linking Identifier

v: Computable Publishing LLC

v: FEvIR Linking Identifier

v: MAGIC-5288-j1Wqrn-dichotomous-outcome-313883-comparative-evidence

display:
  v: Computable Publishing LLC

v: MAGIC-derived Evidence: Severe gastrointestinal events with GLP-1 RA vs. Standard care in Adults with type 2 diabetes with moderate CV risk

title:
  v: Effect Estimate
code:
  coding:
    system:
      v: https://fevir.net/resources/CodeSystem/179423
      l: https://fevir.net/resources/CodeSystem/179423
    code:
      v: result-with-intervention-vs-comparator
    display:
      v: Result with intervention vs. comparator
text:
  status:
    v: generated
  div:
    v: 5.77% (0.92% to 14.22%)
entry:
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  reference:
    v: Evidence/236561
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    v: Evidence
    l: Evidence
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    type:
      text:
        v: FEvIR Linking Identifier
    system:
      v: https://fevir.net/FLI
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    value:
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    assigner:
      display:
        v: Computable Publishing LLC
  display:
    v: MAGIC-derived Evidence: Severe gastrointestinal events with GLP-1 RA vs. Standard care in Adults with type 2 diabetes with moderate CV risk

title:
  v: Certainty of Evidence
code:
  coding:
    system:
      v: https://fevir.net/resources/CodeSystem/179423
      l: https://fevir.net/resources/CodeSystem/179423
    code:
      v: certainty-of-evidence
    display:
      v: Certainty of Evidence
text:
  status:
    v: generated
  div:
    v: Low certainty -- Due to inconsistency and serious imprecision.
entry:
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    v: Evidence/236561
  type:
    v: Evidence
    l: Evidence
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    type:
      text:
        v: FEvIR Linking Identifier
    system:
      v: https://fevir.net/FLI
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    value:
      v: MAGIC-5288-j1Wqrn-dichotomous-outcome-313883-comparative-evidence
    assigner:
      display:
        v: Computable Publishing LLC
  display:
    v: MAGIC-derived Evidence: Severe gastrointestinal events with GLP-1 RA vs. Standard care in Adults with type 2 diabetes with moderate CV risk

title:
  v: Assertion
code:
  coding:
    system:
      v: https://fevir.net/resources/CodeSystem/179423
      l: https://fevir.net/resources/CodeSystem/179423
    code:
      v: assertion
    display:
      v: Assertion
text:
  status:
    v: generated
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    v: GLP-1 receptor agonists may increase the risk of severe gastrointestinal events compared with standard care.
entry:
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  reference:
    v: Evidence/236561
  type:
    v: Evidence
    l: Evidence
  identifier:
    type:
      text:
        v: FEvIR Linking Identifier
    system:
      v: https://fevir.net/FLI
      l: FLI
    value:
      v: MAGIC-5288-j1Wqrn-dichotomous-outcome-313883-comparative-evidence
    assigner:
      display:
        v: Computable Publishing LLC
  display:
    v: MAGIC-derived Evidence: Severe gastrointestinal events with GLP-1 RA vs. Standard care in Adults with type 2 diabetes with moderate CV risk

title:
  v: Health-related quality of life
code:
  coding:
    system:
      v: https://fevir.net/resources/CodeSystem/179423
      l: https://fevir.net/resources/CodeSystem/179423
    code:
      v: summary-of-findings-entry-for-a-single-outcome
    display:
      v: Summary of findings entry for a single outcome
focus:
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    v: EvidenceVariable
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  identifier:
    type:
      text:
        v: FEvIR Linking Identifier
    system:
      v: https://fevir.net/FLI
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    value:
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    assigner:
      display:
        v: Computable Publishing LLC
  display:
    v: OutcomeDefinition: Health-related quality of life
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    v: Outcome
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    coding:
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      code:
        v: outcome-measure
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        v: Outcome Measure
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    status:
      v: generated
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      v: OutcomeDefinition: Health-related quality of life
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      v: EvidenceVariable/236563
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      v: EvidenceVariable
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    identifier:
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        v: https://fevir.net/FLI
        l: FLI
      value:
        v: MAGIC-5288-j1Wqrn-109569
    display:
      v: OutcomeDefinition: Health-related quality of life
section:
  title:
    v: Sample Size
  code:
    coding:
      system:
        v: https://fevir.net/resources/CodeSystem/179423
        l: https://fevir.net/resources/CodeSystem/179423
      code:
        v: sample-size
      display:
        v: Sample Size
  text:
    status:
      v: generated
    div:
      v: [No sample size data.]
  entry:
    l: http://hl7.org/fhir/uv/ebm/Evidence/236564
    reference:
      v: Evidence/236564
    type:
      v: Evidence
      l: Evidence
    identifier:
      system:
        v: https://fevir.net/FLI
        l: FLI
      value:
        v: MAGIC-5288-j1Wqrn-continuous-outcome-109569-comparative-evidence
    display:
      v: MAGIC-derived Evidence: Health-related quality of life with GLP-1 RA vs. Standard care in Adults with type 2 diabetes with moderate CV risk
section:
  title:
    v: Result Without Treatment
  code:
    coding:
      system:
        v: https://fevir.net/resources/CodeSystem/179423
        l: https://fevir.net/resources/CodeSystem/179423
      code:
        v: result-with-comparator-alone
      display:
        v: Result with comparator alone
  text:
    status:
      v: generated
    div:
      v: [Not a proportion.]
  entry:
    l: http://hl7.org/fhir/uv/ebm/Evidence/236565
    reference:
      v: Evidence/236565
    type:
      v: Evidence
      l: Evidence
    identifier:
      system:
        v: https://fevir.net/FLI
        l: FLI
      value:
        v: MAGIC-5288-j1Wqrn-continuous-outcome-109569-comparator-only-evidence
    display:
      v: MAGIC-derived ComparatorOnlyEvidence: Health-related quality of life in Standard care Group in Adults with type 2 diabetes with moderate CV risk
section:
  title:
    v: Result With Treatment--Observed
  code:
    coding:
      system:
        v: https://fevir.net/resources/CodeSystem/179423
        l: https://fevir.net/resources/CodeSystem/179423
      code:
        v: result-with-intervention-alone
      display:
        v: Result with intervention alone
  text:
    status:
      v: generated
    div:
      v: [Not a proportion.]
  entry:
    l: http://hl7.org/fhir/uv/ebm/Evidence/293880
    reference:
      v: Evidence/293880
    type:
      v: Evidence
      l: Evidence
    identifier:
      system:
        v: https://fevir.net/FLI
        l: FLI
      value:
        v: MAGIC-5288-j1Wqrn-continuous-outcome-109569-intervention-only-evidence
    display:
      v: MAGIC-derived InterventionOnlyEvidence: Health-related quality of life in GLP-1 RA Group in Adults with type 2 diabetes with moderate CV risk
section:
  title:
    v: Result With Treatment--Derived
  code:
    coding:
      system:
        v: https://fevir.net/resources/CodeSystem/179423
        l: https://fevir.net/resources/CodeSystem/179423
      code:
        v: result-with-intervention-alone-calculated
      display:
        v: Result with intervention alone (calculated)
    text:
      v: result with intervention with calculated value derived from the control group and effect estimate
  text:
    status:
      v: generated
    div:
      v: [Not a proportion.]
  entry:
    l: http://hl7.org/fhir/uv/ebm/Evidence/236565
    reference:
      v: Evidence/236565
    type:
      v: Evidence
      l: Evidence
    identifier:
      system:
        v: https://fevir.net/FLI
        l: FLI
      value:
        v: MAGIC-5288-j1Wqrn-continuous-outcome-109569-comparator-only-evidence
    display:
      v: MAGIC-derived ComparatorOnlyEvidence: Health-related quality of life in Standard care Group in Adults with type 2 diabetes with moderate CV risk
  entry:
    l: http://hl7.org/fhir/uv/ebm/Evidence/236564
    reference:
      v: Evidence/236564
    type:
      v: Evidence
      l: Evidence
    identifier:
      system:
        v: https://fevir.net/FLI
        l: FLI

v: FEvIR Linking Identifier

v: Computable Publishing LLC

v: FEvIR Linking Identifier

v: Computable Publishing LLC

v: FEvIR Linking Identifier

v: Computable Publishing LLC

v: FEvIR Linking Identifier

v: Computable Publishing LLC

v: FEvIR Linking Identifier

v: Computable Publishing LLC

v: FEvIR Linking Identifier

v: MAGIC-5288-j1Wqrn-continuous-outcome-109569-comparative-evidence

display:
  v: Computable Publishing LLC

v: MAGIC-derived Evidence: Health-related quality of life with GLP-1 RA vs. Standard care in Adults with type 2 diabetes with moderate CV risk

title:
  v: Effect Estimate
code:
  coding:
    system:
      v: https://fevir.net/resources/CodeSystem/179423
      l: https://fevir.net/resources/CodeSystem/179423
    code:
      v: result-with-intervention-vs-comparator
    display:
      v: Result with intervention vs. comparator
text:
  status:
    v: generated
  div:
    v: [Not a difference in proportions.]
entry:
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  reference:
    v: Evidence/236564
  type:
    v: Evidence
    l: Evidence
  identifier:
    type:
      text:
        v: FEvIR Linking Identifier
    system:
      v: https://fevir.net/FLI
      l: FLI
    value:
      v: MAGIC-5288-j1Wqrn-continuous-outcome-109569-comparative-evidence
    assigner:
      display:
        v: Computable Publishing LLC
  display:
    v: MAGIC-derived Evidence: Health-related quality of life with GLP-1 RA vs. Standard care in Adults with type 2 diabetes with moderate CV risk

title:
  v: Certainty of Evidence
code:
  coding:
    system:
      v: https://fevir.net/resources/CodeSystem/179423
      l: https://fevir.net/resources/CodeSystem/179423
    code:
      v: certainty-of-evidence
    display:
      v: Certainty of Evidence
text:
  status:
    v: generated
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    v: Low certainty -- Due to very serious imprecision
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  reference:
    v: Evidence/236564
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    v: Evidence
    l: Evidence
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    type:
      text:
        v: FEvIR Linking Identifier
    system:
      v: https://fevir.net/FLI
      l: FLI
    value:
      v: MAGIC-5288-j1Wqrn-continuous-outcome-109569-comparative-evidence
    assigner:
      display:
        v: Computable Publishing LLC
  display:
    v: MAGIC-derived Evidence: Health-related quality of life with GLP-1 RA vs. Standard care in Adults with type 2 diabetes with moderate CV risk

title:
  v: Assertion
code:
  coding:
    system:
      v: https://fevir.net/resources/CodeSystem/179423
      l: https://fevir.net/resources/CodeSystem/179423
    code:
      v: assertion
    display:
      v: Assertion
text:
  status:
    v: generated
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    v: GLP-1 receptor agonists may have little or no impact on health-related quality of life.
entry:
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  reference:
    v: Evidence/236564
  type:
    v: Evidence
    l: Evidence
  identifier:
    type:
      text:
        v: FEvIR Linking Identifier
    system:
      v: https://fevir.net/FLI
      l: FLI
    value:
      v: MAGIC-5288-j1Wqrn-continuous-outcome-109569-comparative-evidence
    assigner:
      display:
        v: Computable Publishing LLC
  display:
    v: MAGIC-derived Evidence: Health-related quality of life with GLP-1 RA vs. Standard care in Adults with type 2 diabetes with moderate CV risk

title:
  v: Body weight
code:
  coding:
    system:
      v: https://fevir.net/resources/CodeSystem/179423
      l: https://fevir.net/resources/CodeSystem/179423
    code:
      v: summary-of-findings-entry-for-a-single-outcome
    display:
      v: Summary of findings entry for a single outcome
focus:
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    v: EvidenceVariable/236566
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    v: EvidenceVariable
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  identifier:
    type:
      text:
        v: FEvIR Linking Identifier
    system:
      v: https://fevir.net/FLI
      l: FLI
    value:
      v: MAGIC-5288-j1Wqrn-109570
    assigner:
      display:
        v: Computable Publishing LLC
  display:
    v: OutcomeDefinition: Body weight
section:
  title:
    v: Outcome
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    coding:
      system:
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        l: https://fevir.net/resources/CodeSystem/179423
      code:
        v: outcome-measure
      display:
        v: Outcome Measure
  text:
    status:
      v: generated
    div:
      v: OutcomeDefinition: Body weight
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    reference:
      v: EvidenceVariable/236566
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      v: EvidenceVariable
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      system:
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        l: FLI
      value:
        v: MAGIC-5288-j1Wqrn-109570
    display:
      v: OutcomeDefinition: Body weight
section:
  title:
    v: Sample Size
  code:
    coding:
      system:
        v: https://fevir.net/resources/CodeSystem/179423
        l: https://fevir.net/resources/CodeSystem/179423
      code:
        v: sample-size
      display:
        v: Sample Size
  text:
    status:
      v: generated
    div:
      v: 60 studies, 44432 participants
  entry:
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    reference:
      v: Evidence/236567
    type:
      v: Evidence
      l: Evidence
    identifier:
      system:
        v: https://fevir.net/FLI
        l: FLI
      value:
        v: MAGIC-5288-j1Wqrn-continuous-outcome-109570-comparative-evidence
    display:
      v: MAGIC-derived Evidence: Body weight with GLP-1 RA vs. Standard care in Adults with type 2 diabetes with moderate CV risk
section:
  title:
    v: Result Without Treatment
  code:
    coding:
      system:
        v: https://fevir.net/resources/CodeSystem/179423
        l: https://fevir.net/resources/CodeSystem/179423
      code:
        v: result-with-comparator-alone
      display:
        v: Result with comparator alone
  text:
    status:
      v: generated
    div:
      v: [Not a proportion.]
  entry:
    l: http://hl7.org/fhir/uv/ebm/Evidence/236568
    reference:
      v: Evidence/236568
    type:
      v: Evidence
      l: Evidence
    identifier:
      system:
        v: https://fevir.net/FLI
        l: FLI
      value:
        v: MAGIC-5288-j1Wqrn-continuous-outcome-109570-comparator-only-evidence
    display:
      v: MAGIC-derived ComparatorOnlyEvidence: Body weight in Standard care Group in Adults with type 2 diabetes with moderate CV risk
section:
  title:
    v: Result With Treatment--Observed
  code:
    coding:
      system:
        v: https://fevir.net/resources/CodeSystem/179423
        l: https://fevir.net/resources/CodeSystem/179423
      code:
        v: result-with-intervention-alone
      display:
        v: Result with intervention alone
  text:
    status:
      v: generated
    div:
      v: [Not a proportion.]
  entry:
    l: http://hl7.org/fhir/uv/ebm/Evidence/293881
    reference:
      v: Evidence/293881
    type:
      v: Evidence
      l: Evidence
    identifier:
      system:
        v: https://fevir.net/FLI
        l: FLI
      value:
        v: MAGIC-5288-j1Wqrn-continuous-outcome-109570-intervention-only-evidence
    display:
      v: MAGIC-derived InterventionOnlyEvidence: Body weight in GLP-1 RA Group in Adults with type 2 diabetes with moderate CV risk
section:
  title:
    v: Result With Treatment--Derived
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    coding:
      system:
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        l: https://fevir.net/resources/CodeSystem/179423
      code:
        v: result-with-intervention-alone-calculated
      display:
        v: Result with intervention alone (calculated)
    text:
      v: result with intervention with calculated value derived from the control group and effect estimate
  text:
    status:
      v: generated
    div:
      v: [Not a proportion.]
  entry:
    l: http://hl7.org/fhir/uv/ebm/Evidence/236568
    reference:
      v: Evidence/236568
    type:
      v: Evidence
      l: Evidence
    identifier:
      system:
        v: https://fevir.net/FLI
        l: FLI
      value:
        v: MAGIC-5288-j1Wqrn-continuous-outcome-109570-comparator-only-evidence
    display:
      v: MAGIC-derived ComparatorOnlyEvidence: Body weight in Standard care Group in Adults with type 2 diabetes with moderate CV risk
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    reference:
      v: Evidence/236567
    type:
      v: Evidence
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    identifier:
      system:
        v: https://fevir.net/FLI
        l: FLI

v: FEvIR Linking Identifier

v: Computable Publishing LLC

v: FEvIR Linking Identifier

v: Computable Publishing LLC

v: FEvIR Linking Identifier

v: Computable Publishing LLC

v: FEvIR Linking Identifier

v: Computable Publishing LLC

v: FEvIR Linking Identifier

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v: FEvIR Linking Identifier

v: MAGIC-5288-j1Wqrn-continuous-outcome-109570-comparative-evidence

display:
  v: Computable Publishing LLC

v: MAGIC-derived Evidence: Body weight with GLP-1 RA vs. Standard care in Adults with type 2 diabetes with moderate CV risk

title:
  v: Effect Estimate
code:
  coding:
    system:
      v: https://fevir.net/resources/CodeSystem/179423
      l: https://fevir.net/resources/CodeSystem/179423
    code:
      v: result-with-intervention-vs-comparator
    display:
      v: Result with intervention vs. comparator
text:
  status:
    v: generated
  div:
    v: [Not a difference in proportions.]
entry:
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  reference:
    v: Evidence/236567
  type:
    v: Evidence
    l: Evidence
  identifier:
    type:
      text:
        v: FEvIR Linking Identifier
    system:
      v: https://fevir.net/FLI
      l: FLI
    value:
      v: MAGIC-5288-j1Wqrn-continuous-outcome-109570-comparative-evidence
    assigner:
      display:
        v: Computable Publishing LLC
  display:
    v: MAGIC-derived Evidence: Body weight with GLP-1 RA vs. Standard care in Adults with type 2 diabetes with moderate CV risk

title:
  v: Certainty of Evidence
code:
  coding:
    system:
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      l: https://fevir.net/resources/CodeSystem/179423
    code:
      v: certainty-of-evidence
    display:
      v: Certainty of Evidence
text:
  status:
    v: generated
  div:
    v: Low certainty -- Due to very serious inconsistency
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  reference:
    v: Evidence/236567
  type:
    v: Evidence
    l: Evidence
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    type:
      text:
        v: FEvIR Linking Identifier
    system:
      v: https://fevir.net/FLI
      l: FLI
    value:
      v: MAGIC-5288-j1Wqrn-continuous-outcome-109570-comparative-evidence
    assigner:
      display:
        v: Computable Publishing LLC
  display:
    v: MAGIC-derived Evidence: Body weight with GLP-1 RA vs. Standard care in Adults with type 2 diabetes with moderate CV risk

title:
  v: Assertion
code:
  coding:
    system:
      v: https://fevir.net/resources/CodeSystem/179423
      l: https://fevir.net/resources/CodeSystem/179423
    code:
      v: assertion
    display:
      v: Assertion
text:
  status:
    v: generated
  div:
    v: GLP-1 receptor agonists may reduce body weight compared with standard care.
entry:
  l: http://hl7.org/fhir/uv/ebm/Evidence/236567
  reference:
    v: Evidence/236567
  type:
    v: Evidence
    l: Evidence
  identifier:
    type:
      text:
        v: FEvIR Linking Identifier
    system:
      v: https://fevir.net/FLI
      l: FLI
    value:
      v: MAGIC-5288-j1Wqrn-continuous-outcome-109570-comparative-evidence
    assigner:
      display:
        v: Computable Publishing LLC
  display:
    v: MAGIC-derived Evidence: Body weight with GLP-1 RA vs. Standard care in Adults with type 2 diabetes with moderate CV risk