Evidence Based Medicine on FHIR Implementation Guide, published by HL7 International / Clinical Decision Support. This guide is not an authorized publication; it is the continuous build for version 1.0.0-ballot3 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/ebm/ and changes regularly. See the Directory of published versions
{
"resourceType" : "Citation",
"id" : "58",
"meta" : {
"versionId" : "32",
"lastUpdated" : "2025-10-13T16:59:33.089Z"
},
"language" : "en",
"text" : {
"status" : "extensions",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\" xml:lang=\"en\" lang=\"en\"><p class=\"res-header-id\"><b>Generated Narrative: Citation 58</b></p><a name=\"58\"> </a><a name=\"hc58\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">version: 32; Last updated: 2025-10-13 16:59:33+0000; Language: en</p></div><p><b>ArtifactPublicationStatus</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/cited-artifact-status-type active}\">Active</span></p><p><b>url</b>: <a href=\"https://fevir.net/resources/Citation/58\">https://fevir.net/resources/Citation/58</a></p><p><b>identifier</b>: FEvIR Object Identifier/58</p><p><b>title</b>: Citation for FEvIR Evidence 55: 14-day mortality remdesivir vs placebo meta-analysis (ACTT-1, Wang et al, WHO SOLIDARITY)</p><p><b>status</b>: Active</p><p><b>date</b>: 2022-01-10 13:29:15+0000</p><p><b>author</b>: Brian S. Alper: </p><p><b>publisher</b>: Computable Publishing LLC</p><p><b>contact</b>: <a href=\"mailto:support@computablepublishing.com\">support@computablepublishing.com</a></p><p><b>description</b>: </p><div><p>This Citation Resource is referenced in an example for the EBMonFHIR Implementation Guide.</p>\n</div><h3>UseContexts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"http://terminology.hl7.org/7.1.0/CodeSystem-citation-classification-type.html#citation-classification-type-fevir-platform-use\">Citation Classification Type: fevir-platform-use</a> (FEvIR Platform Use)</td><td><span title=\"Codes:{http://terminology.hl7.org/CodeSystem/citation-artifact-classifier fhir-resource}\">FHIR Resource</span></td></tr></table><p><b>copyright</b>: </p><div><p>https://creativecommons.org/licenses/by-nc-sa/4.0/</p>\n</div><h3>Summaries</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Style</b></td><td><b>Text</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://terminology.hl7.org/CodeSystem/citation-summary-style comppub}\">Computable Publishing</span></td><td><div><p>14-day mortality remdesivir vs placebo meta-analysis (ACTT-1, Wang et al, WHO SOLIDARITY) [FHIR Resource], version 4. Contributors: Brian S. Alper, Joanne Dehnbostel, Khalid Shahin [Authors]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 55. Created December 17, 2020. Revised December 21, 2020. Accessed March 13, 2021. Available at: https://fevir.net/resources/Evidence/55. Computable resource at: https://fevir.net/resources/Evidence/55.</p>\n</div></td></tr></table><h3>RelatesTos</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Target[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Derived From</td><td><a href=\"Evidence-55.html\">14-day mortality remdesivir vs placebo meta-analysis (ACTT-1, Wang et al, WHO SOLIDARITY)</a></td></tr></table><blockquote><p><b>citedArtifact</b></p><p><b>identifier</b>: FEvIR Object Identifier/55</p><p><b>dateAccessed</b>: 2021-03-13</p><h3>StatusDates</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Activity</b></td><td><b>Actual</b></td><td><b>Period</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://terminology.hl7.org/CodeSystem/cited-artifact-status-type created}\">Created</span></td><td>true</td><td>?? --> 2020-12-17</td></tr></table><h3>Titles</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Text</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://terminology.hl7.org/CodeSystem/title-type primary}\">Primary title</span></td><td><div><p>14-day mortality remdesivir vs placebo meta-analysis (ACTT-1, Wang et al, WHO SOLIDARITY).</p>\n</div></td></tr></table><h3>Abstracts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Text</b></td><td><b>Copyright</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://terminology.hl7.org/CodeSystem/cited-artifact-abstract-type primary-human-use}\">Primary human use</span></td><td><div><p>COVID-19 pneumonia remdesivir vs. placebo 14-day mortality (779 events among 6,744 participants, 3 randomized trials)\\nRisk ratio 0.85 (95% CI 0.74 to 0.96) in fixed-effect analysis\\nRisk ratio 0.81 (95% CI 0.60 to 1.08) in random-effects analysis</p>\n</div></td><td><div><p>https://creativecommons.org/licenses/by-nc-sa/4.0/</p>\n</div></td></tr></table><blockquote><p><b>publicationForm</b></p><h3>PublishedIns</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Title</b></td><td><b>Publisher</b></td><td><b>PublisherLocation</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://terminology.hl7.org/CodeSystem/published-in-type D019991}\">Database</span></td><td>Fast Evidence Interoperability Resources (FEvIR) Platform</td><td>Computable Publishing LLC</td><td>Ipswich, MA, USA</td></tr></table><p><b>lastRevisionDate</b>: 2020-12-21</p><p><b>copyright</b>: </p><div><p>https://creativecommons.org/licenses/by-nc-sa/4.0/</p>\n</div></blockquote><blockquote><p><b>webLocation</b></p><p><b>classifier</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/artifact-url-classifier json}\">JSON</span>, <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/artifact-url-classifier computable-resource}\">Computable resource</span></p><p><b>url</b>: <a href=\"https://fevir.net/resources/Evidence/55\">https://fevir.net/resources/Evidence/55</a></p></blockquote><blockquote><p><b>classification</b></p><p><b>type</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/cited-artifact-classification-type knowledge-artifact-type}\">Knowledge Artifact Type</span></p><p><b>classifier</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/citation-artifact-classifier fhir-resource}\">FHIR Resource</span></p></blockquote><blockquote><p><b>classification</b></p><p><b>type</b>: <span title=\"Codes:\">fhir-resource</span></p><p><b>classifier</b>: <span title=\"Codes:{http://hl7.org/fhir/fhir-types Evidence}\">Evidence</span></p></blockquote><blockquote><p><b>classification</b></p><p><b>type</b>: <span title=\"Codes:\">defined-in-text</span></p><p><b>classifier</b>: <span title=\"Codes:{https://fevir.net/resources/CodeSystem/179423 defined-in-text}\">remdesivir</span>, <span title=\"Codes:{https://fevir.net/resources/CodeSystem/179423 defined-in-text}\">COVID-19</span>, <span title=\"Codes:{https://fevir.net/resources/CodeSystem/179423 defined-in-text}\">pharmaceutical treatment</span></p></blockquote><blockquote><p><b>contributorship</b></p><p><b>complete</b>: true</p><blockquote><p><b>entry</b></p><p><b>contributor</b>: <a href=\"#hc58/contributor0\">Practitioner Brian S. Alper </a></p><p><b>forenameInitials</b>: BS</p><p><b>affiliation</b>: Computable Publishing LLC</p><p><b>contributionType</b>: <span title=\"Codes:{http://hl7.org/fhir/artifact-contribution-type conceptualization}\">Conceptualization</span>, <span title=\"Codes:{http://hl7.org/fhir/artifact-contribution-type data-curation}\">Data curation</span>, <span title=\"Codes:{http://hl7.org/fhir/artifact-contribution-type supervision}\">Supervision</span></p><p><b>role</b>: <span title=\"Codes:{http://hl7.org/fhir/contributor-role author}\">Author/Creator</span></p><p><b>correspondingContact</b>: true</p></blockquote><blockquote><p><b>entry</b></p><p><b>contributor</b>: <a href=\"#hc58/contributor1\">Practitioner Joanne Dehnbostel </a></p><p><b>forenameInitials</b>: J</p><p><b>affiliation</b>: Computable Publishing LLC</p><p><b>contributionType</b>: <span title=\"Codes:{http://hl7.org/fhir/artifact-contribution-type formal-analysis}\">Formal analysis</span>, <span title=\"Codes:{http://hl7.org/fhir/artifact-contribution-type data-curation}\">Data curation</span></p><p><b>role</b>: <span title=\"Codes:{http://hl7.org/fhir/contributor-role author}\">Author/Creator</span></p><p><b>correspondingContact</b>: false</p></blockquote><blockquote><p><b>entry</b></p><p><b>contributor</b>: <a href=\"#hc58/contributor2\">Practitioner Khalid Shahin </a></p><p><b>forenameInitials</b>: K</p><p><b>affiliation</b>: Computable Publishing LLC</p><p><b>contributionType</b>: <span title=\"Codes:{http://hl7.org/fhir/artifact-contribution-type software}\">Software</span></p><p><b>role</b>: <span title=\"Codes:{http://hl7.org/fhir/contributor-role author}\">Author/Creator</span></p><p><b>correspondingContact</b>: false</p></blockquote></blockquote></blockquote><hr/><blockquote><p class=\"res-header-id\"><b>Generated Narrative: Practitioner #contributor0</b></p><a name=\"58/contributor0\"> </a><a name=\"hc58/contributor0\"> </a><p><b>identifier</b>: <code>https://orcid.org/</code>/0000-0003-4300-4928</p><p><b>name</b>: Brian S. Alper </p><p><b>telecom</b>: <a href=\"mailto:balper@computablepublishing.com\">balper@computablepublishing.com</a></p></blockquote><hr/><blockquote><p class=\"res-header-id\"><b>Generated Narrative: Practitioner #contributor1</b></p><a name=\"58/contributor1\"> </a><a name=\"hc58/contributor1\"> </a><p><b>name</b>: Joanne Dehnbostel </p><p><b>telecom</b>: <a href=\"mailto:jdehnbostel@computablepublishing.com\">jdehnbostel@computablepublishing.com</a></p></blockquote><hr/><blockquote><p class=\"res-header-id\"><b>Generated Narrative: Practitioner #contributor2</b></p><a name=\"58/contributor2\"> </a><a name=\"hc58/contributor2\"> </a><p><b>name</b>: Khalid Shahin </p><p><b>telecom</b>: <a href=\"mailto:kshahin@computablepublishing.com\">kshahin@computablepublishing.com</a></p></blockquote></div>"
},
"contained" : [
{
"resourceType" : "Practitioner",
"id" : "contributor0",
"identifier" : [
{
"system" : "https://orcid.org/",
"value" : "0000-0003-4300-4928",
"assigner" : {
"display" : "ORCID"
}
}
],
"name" : [
{
"family" : "Alper",
"given" : [
"Brian S."
]
}
],
"telecom" : [
{
"system" : "email",
"value" : "balper@computablepublishing.com"
}
]
},
{
"resourceType" : "Practitioner",
"id" : "contributor1",
"name" : [
{
"family" : "Dehnbostel",
"given" : [
"Joanne"
]
}
],
"telecom" : [
{
"system" : "email",
"value" : "jdehnbostel@computablepublishing.com"
}
]
},
{
"resourceType" : "Practitioner",
"id" : "contributor2",
"name" : [
{
"family" : "Shahin",
"given" : [
"Khalid"
]
}
],
"telecom" : [
{
"system" : "email",
"value" : "kshahin@computablepublishing.com"
}
]
}
],
"extension" : [
{
"url" : "http://hl7.org/fhir/uv/ebm/StructureDefinition/artifact-publication-status",
"valueCodeableConcept" : {
"coding" : [
{
"system" : "http://terminology.hl7.org/CodeSystem/cited-artifact-status-type",
"code" : "active",
"display" : "Active"
}
]
}
}
],
"url" : "https://fevir.net/resources/Citation/58",
"identifier" : [
{
"type" : {
"coding" : [
{
"system" : "http://terminology.hl7.org/CodeSystem/v2-0203",
"code" : "ACSN",
"display" : "Accession ID"
}
],
"text" : "FEvIR Object Identifier"
},
"system" : "https://fevir.net/FOI",
"value" : "58",
"assigner" : {
"display" : "Computable Publishing LLC"
}
}
],
"title" : "Citation for FEvIR Evidence 55: 14-day mortality remdesivir vs placebo meta-analysis (ACTT-1, Wang et al, WHO SOLIDARITY)",
"status" : "active",
"date" : "2022-01-10T13:29:15.764Z",
"author" : [
{
"name" : "Brian S. Alper"
}
],
"publisher" : "Computable Publishing LLC",
"contact" : [
{
"telecom" : [
{
"system" : "email",
"value" : "support@computablepublishing.com"
}
]
}
],
"description" : "This Citation Resource is referenced in an example for the EBMonFHIR Implementation Guide.",
"useContext" : [
{
"code" : {
"system" : "http://terminology.hl7.org/CodeSystem/citation-classification-type",
"code" : "fevir-platform-use",
"display" : "FEvIR Platform Use"
},
"valueCodeableConcept" : {
"coding" : [
{
"system" : "http://terminology.hl7.org/CodeSystem/citation-artifact-classifier",
"code" : "fhir-resource",
"display" : "FHIR Resource"
}
]
}
}
],
"copyright" : "https://creativecommons.org/licenses/by-nc-sa/4.0/",
"summary" : [
{
"style" : {
"coding" : [
{
"system" : "http://terminology.hl7.org/CodeSystem/citation-summary-style",
"code" : "comppub",
"display" : "Computable Publishing"
}
]
},
"text" : "14-day mortality remdesivir vs placebo meta-analysis (ACTT-1, Wang et al, WHO SOLIDARITY) [FHIR Resource], version 4. Contributors: Brian S. Alper, Joanne Dehnbostel, Khalid Shahin [Authors]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 55. Created December 17, 2020. Revised December 21, 2020. Accessed March 13, 2021. Available at: https://fevir.net/resources/Evidence/55. Computable resource at: https://fevir.net/resources/Evidence/55."
}
],
"relatesTo" : [
{
"type" : "derived-from",
"targetReference" : {
🔗 "reference" : "Evidence/55",
"type" : "Evidence",
"display" : "14-day mortality remdesivir vs placebo meta-analysis (ACTT-1, Wang et al, WHO SOLIDARITY)"
}
}
],
"citedArtifact" : {
"identifier" : [
{
"type" : {
"coding" : [
{
"system" : "http://terminology.hl7.org/CodeSystem/v2-0203",
"code" : "ACSN",
"display" : "Accession ID"
}
],
"text" : "FEvIR Object Identifier"
},
"system" : "https://fevir.net",
"value" : "55",
"assigner" : {
"display" : "Computable Publishing LLC"
}
}
],
"dateAccessed" : "2021-03-13",
"statusDate" : [
{
"activity" : {
"coding" : [
{
"system" : "http://terminology.hl7.org/CodeSystem/cited-artifact-status-type",
"code" : "created",
"display" : "Created"
}
]
},
"actual" : true,
"period" : {
"end" : "2020-12-17"
}
}
],
"title" : [
{
"type" : [
{
"coding" : [
{
"system" : "http://terminology.hl7.org/CodeSystem/title-type",
"code" : "primary",
"display" : "Primary title"
}
]
}
],
"text" : "14-day mortality remdesivir vs placebo meta-analysis (ACTT-1, Wang et al, WHO SOLIDARITY)."
}
],
"abstract" : [
{
"type" : [
{
"coding" : [
{
"system" : "http://terminology.hl7.org/CodeSystem/cited-artifact-abstract-type",
"code" : "primary-human-use",
"display" : "Primary human use"
}
]
}
],
"text" : "COVID-19 pneumonia remdesivir vs. placebo 14-day mortality (779 events among 6,744 participants, 3 randomized trials)\\nRisk ratio 0.85 (95% CI 0.74 to 0.96) in fixed-effect analysis\\nRisk ratio 0.81 (95% CI 0.60 to 1.08) in random-effects analysis",
"copyright" : "https://creativecommons.org/licenses/by-nc-sa/4.0/"
}
],
"publicationForm" : [
{
"publishedIn" : {
"type" : {
"coding" : [
{
"system" : "http://terminology.hl7.org/CodeSystem/published-in-type",
"code" : "D019991",
"display" : "Database"
}
]
},
"title" : "Fast Evidence Interoperability Resources (FEvIR) Platform",
"publisher" : {
"type" : "Organization",
"display" : "Computable Publishing LLC"
},
"publisherLocation" : "Ipswich, MA, USA"
},
"lastRevisionDate" : "2020-12-21",
"copyright" : "https://creativecommons.org/licenses/by-nc-sa/4.0/"
}
],
"webLocation" : [
{
"classifier" : [
{
"coding" : [
{
"system" : "http://terminology.hl7.org/CodeSystem/artifact-url-classifier",
"code" : "json",
"display" : "JSON"
}
]
},
{
"coding" : [
{
"system" : "http://terminology.hl7.org/CodeSystem/artifact-url-classifier",
"code" : "computable-resource",
"display" : "Computable resource"
}
]
}
],
"url" : "https://fevir.net/resources/Evidence/55"
}
],
"classification" : [
{
"type" : {
"coding" : [
{
"system" : "http://terminology.hl7.org/CodeSystem/cited-artifact-classification-type",
"code" : "knowledge-artifact-type",
"display" : "Knowledge Artifact Type"
}
]
},
"classifier" : [
{
"coding" : [
{
"system" : "http://terminology.hl7.org/CodeSystem/citation-artifact-classifier",
"code" : "fhir-resource",
"display" : "FHIR Resource"
}
]
}
]
},
{
"type" : {
"text" : "fhir-resource"
},
"classifier" : [
{
"coding" : [
{
"system" : "http://hl7.org/fhir/fhir-types",
"code" : "Evidence",
"display" : "Evidence"
}
]
}
]
},
{
"type" : {
"text" : "defined-in-text"
},
"classifier" : [
{
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "defined-in-text",
"display" : "Defined in text"
}
],
"text" : "remdesivir"
},
{
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "defined-in-text",
"display" : "Defined in text"
}
],
"text" : "COVID-19"
},
{
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "defined-in-text",
"display" : "Defined in text"
}
],
"text" : "pharmaceutical treatment"
}
]
}
],
"contributorship" : {
"complete" : true,
"entry" : [
{
"contributor" : {
"reference" : "#contributor0",
"type" : "Practitioner"
},
"forenameInitials" : "BS",
"affiliation" : [
{
"display" : "Computable Publishing LLC"
}
],
"contributionType" : [
{
"coding" : [
{
"system" : "http://hl7.org/fhir/artifact-contribution-type",
"code" : "conceptualization",
"display" : "Conceptualization"
}
]
},
{
"coding" : [
{
"system" : "http://hl7.org/fhir/artifact-contribution-type",
"code" : "data-curation",
"display" : "Data curation"
}
]
},
{
"coding" : [
{
"system" : "http://hl7.org/fhir/artifact-contribution-type",
"code" : "supervision",
"display" : "Supervision"
}
]
}
],
"role" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/contributor-role",
"code" : "author",
"display" : "Author/Creator"
}
]
},
"correspondingContact" : true
},
{
"contributor" : {
"reference" : "#contributor1",
"type" : "Practitioner"
},
"forenameInitials" : "J",
"affiliation" : [
{
"display" : "Computable Publishing LLC"
}
],
"contributionType" : [
{
"coding" : [
{
"system" : "http://hl7.org/fhir/artifact-contribution-type",
"code" : "formal-analysis",
"display" : "Formal analysis"
}
]
},
{
"coding" : [
{
"system" : "http://hl7.org/fhir/artifact-contribution-type",
"code" : "data-curation",
"display" : "Data curation"
}
]
}
],
"role" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/contributor-role",
"code" : "author",
"display" : "Author/Creator"
}
]
},
"correspondingContact" : false
},
{
"contributor" : {
"reference" : "#contributor2",
"type" : "Practitioner"
},
"forenameInitials" : "K",
"affiliation" : [
{
"display" : "Computable Publishing LLC"
}
],
"contributionType" : [
{
"coding" : [
{
"system" : "http://hl7.org/fhir/artifact-contribution-type",
"code" : "software",
"display" : "Software"
}
]
}
],
"role" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/contributor-role",
"code" : "author",
"display" : "Author/Creator"
}
]
},
"correspondingContact" : false
}
]
}
}
}