Evidence Based Medicine on FHIR Implementation Guide
1.0.0-ballot2 - STU 1 ballot
Evidence Based Medicine on FHIR Implementation Guide
1.0.0-ballot2 - STU 1 ballot
Evidence Based Medicine on FHIR Implementation Guide, published by HL7 International / Clinical Decision Support. This guide is not an authorized publication; it is the continuous build for version 1.0.0-ballot2 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/ebm/ and changes regularly. See the Directory of published versions
| Page standards status: Informative |
@prefix fhir: <http://hl7.org/fhir/> . @prefix owl: <http://www.w3.org/2002/07/owl#> . @prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> . @prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> . @prefix xsd: <http://www.w3.org/2001/XMLSchema#> . # - resource ------------------------------------------------------------------- a fhir:Composition ; fhir:nodeRole fhir:treeRoot ; fhir:id [ fhir:v "397488"] ; # fhir:meta [ fhir:versionId [ fhir:v "9" ] ; fhir:lastUpdated [ fhir:v "2025-09-03T12:20:32.624Z"^^xsd:dateTime ] ; ( fhir:profile [ fhir:v "http://hl7.org/fhir/uv/ebm/StructureDefinition/summary-of-findings"^^xsd:anyURI ; fhir:link <http://hl7.org/fhir/uv/ebm/StructureDefinition/summary-of-findings> ] ) ] ; # fhir:text [ fhir:status [ fhir:v "additional" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><table><tbody><tr><th><div><p>Outcome</p></div></th><th><div><p>Sample Size</p></div></th><th><div><p>Result Without Treatment</p></div></th><th><div><p>Result With Treatment (Observed)</p></div></th><th><div><p>Result With Treatment (Calculated)</p></div></th><th><div><p>Effect Estimate</p></div></th><th><div><p>Certainty of Evidence</p></div></th><th><div><p>What this means</p></div></th></tr><tr><td><div><p>Systolic blood pressure at 12 weeks</p></div></td><td><div><p>62 participants, 60 analyzed, 53 without missing data</p></div></td><td><div><div style=\"color: #AAAAAA;\">[No summary statement.]</div></div></td><td><div><div style=\"color: #AAAAAA;\">[No summary statement.]</div></div></td><td><div><div style=\"color: #AAAAAA;\">[No summary statement.]</div></div></td><td><div><p>difference in means -4.5 mm Hg (95% confidence interval -10.82 mm Hg to 1.32 mm Hg)</p></div></td><td><div><div style=\"color: #AAAAAA;\">[No summary statement.]</div></div></td><td><div><div style=\"color: #AAAAAA;\">[No summary statement.]</div></div></td></tr><tr><td><div><p>Diastolic blood pressure at 12 weeks</p></div></td><td><div><p>62 participants, 60 analyzed, 53 without missing data</p></div></td><td><div><div style=\"color: #AAAAAA;\">[No summary statement.]</div></div></td><td><div><div style=\"color: #AAAAAA;\">[No summary statement.]</div></div></td><td><div><p>[Not a proportion.]</p></div></td><td><div><p>difference in means -4.92 mm Hg (95% confidence interval -8.58 mm Hg to 0.27 mm Hg)</p></div></td><td><div><div style=\"color: #AAAAAA;\">[No summary statement.]</div></div></td><td><div><div style=\"color: #AAAAAA;\">[No summary statement.]</div></div></td></tr><tr><td><div><p>Medication Adherence at 12 weeks</p></div></td><td><div><p>62 participants, 53 without missing data</p></div></td><td><div><p>70%</p></div></td><td><div><p>65.6%</p></div></td><td><div><p>46.33%</p></div></td><td><div><p>odds ratio 0.37 (95% confidence interval 0.19 to 2.08)</p></div></td><td><div><div style=\"color: #AAAAAA;\">[No summary statement.]</div></div></td><td><div><div style=\"color: #AAAAAA;\">[No summary statement.]</div></div></td></tr><tr><td><div><p>Hypertension Control at 12 weeks</p></div></td><td><div><p>62 participants, 60 analyzed, 53 without missing data</p></div></td><td><div><p>54.17%</p></div></td><td><div><p>65.52%</p></div></td><td><div><p>77.11%</p></div></td><td><div><p>odds ratio 2.85 (95% confidence interval 0.94 to 8.59)</p></div></td><td><div><div style=\"color: #AAAAAA;\">[No summary statement.]</div></div></td><td><div><div style=\"color: #AAAAAA;\">[No summary statement.]</div></div></td></tr><tr><td><div><p>Add-on Amlodipine at 6 weeks</p></div></td><td><div><p>62 participants, 60 analyzed, 62 without missing data, 22 events</p></div></td><td><div><p>53.33%</p></div></td><td><div><p>18.75%</p></div></td><td><div><p>51.25%</p></div></td><td><div><p>odds ratio 0.92 (95% confidence interval 0.02 to 0.41)</p></div></td><td><div><div style=\"color: #AAAAAA;\">[No summary statement.]</div></div></td><td><div><div style=\"color: #AAAAAA;\">[No summary statement.]</div></div></td></tr><tr><td><div><p>Adverse event free and hypertension control at 12 weeks</p></div></td><td><div><p>62 participants, 53 analyzed, 53 without missing data, 13 events</p></div></td><td><div><p>33.33%</p></div></td><td><div><p>17.24%</p></div></td><td><div><p>29.33%</p></div></td><td><div><p>odds ratio 0.83 (95% confidence interval 0.22 to 3.16)</p></div></td><td><div><div style=\"color: #AAAAAA;\">[No summary statement.]</div></div></td><td><div><div style=\"color: #AAAAAA;\">[No summary statement.]</div></div></td></tr></tbody></table></div>"^^rdf:XMLLiteral ] ; # fhir:url [ fhir:v "https://fevir.net/resources/Composition/397488"^^xsd:anyURI] ; # fhir:identifier ( [ fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/v2-0203"^^xsd:anyURI ] ; fhir:code [ fhir:v "ACSN" ] ; fhir:display [ fhir:v "Accession ID" ] ] ) ; fhir:text [ fhir:v "FEvIR Object Identifier" ] ] ; fhir:system [ fhir:v "https://fevir.net/FOI"^^xsd:anyURI ] ; fhir:value [ fhir:v "397488" ] ; fhir:assigner [ fhir:display [ fhir:v "Computable Publishing LLC" ] ] ] ) ; # fhir:status [ fhir:v "final"] ; # fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "SummaryOfFindings" ] ; fhir:display [ fhir:v "SummaryOfFindings" ] ] ) ; fhir:text [ fhir:v "Summary of Findings" ] ] ; # fhir:date [ fhir:v "2025-09-03T12:20:32.624Z"^^xsd:dateTime] ; # fhir:author ( [ fhir:display [ fhir:v "Brian S. Alper, MD, MSPH" ] ] ) ; # fhir:title [ fhir:v "Summary of Findings - QUARTET USA Trial"] ; # fhir:custodian [ fhir:reference [ fhir:v "Organization/118079" ] ; fhir:type [ fhir:v "Organization"^^xsd:anyURI ] ; fhir:display [ fhir:v "Computable Publishing LLC" ] ] ; # fhir:relatesTo ( [ fhir:type [ fhir:v "derived-from" ] ; fhir:target [ a fhir:Reference ; fhir:reference [ fhir:v "Composition/375280" ] ; fhir:type [ fhir:v "Composition"^^xsd:anyURI ] ; fhir:display [ fhir:v "Outcome Measure Report for QUARTET USA Trial" ] ] ] [ fhir:type [ fhir:v "cite-as" ] ; fhir:target [ a fhir:markdown ; fhir:v "Summary of Findings - QUARTET USA Trial [Database Entry: FHIR Composition Resource]. Contributors: Brian S. Alper, MD, MSPH [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 397488. Revised 2025-09-03. Available at: https://fevir.net/resources/Composition/397488. Computable resource at: https://fevir.net/resources/Composition/397488." ] ] ) ; # fhir:section ( [ fhir:title [ fhir:v "Column Headers" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "column-headers" ] ; fhir:display [ fhir:v "Column Headers" ] ] ) ] ; fhir:text [ fhir:status [ fhir:v "empty" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">No need for narrative text.</div>"^^rdf:XMLLiteral ] ; ( fhir:section [ fhir:title [ fhir:v "Outcome Measure" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "outcome-measure" ] ; fhir:display [ fhir:v "Outcome Measure" ] ] ) ] ; fhir:text [ fhir:status [ fhir:v "generated" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>Outcome</p></div>"^^rdf:XMLLiteral ] ] [ fhir:title [ fhir:v "Sample Size" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; 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fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "result-with-comparator-alone" ] ; fhir:display [ fhir:v "Result with comparator alone" ] ] ) ] ; fhir:text [ fhir:status [ fhir:v "empty" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>[Not a proportion.]</p></div>"^^rdf:XMLLiteral ] ; ( fhir:entry [ fhir:reference [ fhir:v "Evidence/375594" ] ; fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ; fhir:display [ fhir:v "Evidence for Results for Systolic blood pressure at 12 weeks in QUARTET USA Trial Control Group" ] ] ) ] [ fhir:title [ fhir:v "Result With Treatment--Observed" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "result-with-intervention-alone" ] ; fhir:display [ fhir:v "Result with intervention alone" ] ] ) ] ; fhir:text [ fhir:status [ fhir:v "empty" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>[Not a proportion.]</p></div>"^^rdf:XMLLiteral ] ; ( fhir:entry [ fhir:reference [ fhir:v "Evidence/375628" ] ; fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ; fhir:display [ fhir:v "Evidence for Results for Systolic blood pressure at 12 weeks in QUARTET USA Trial Quadpill group" ] ] ) ] [ fhir:title [ fhir:v "Result With Treatment--Derived" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "result-with-intervention-alone-calculated" ] ; fhir:display [ fhir:v "Result with intervention alone (calculated)" ] ] ) ; fhir:text [ fhir:v "result with intervention with calculated value derived from the control group and effect estimate" ] ] ; fhir:text [ fhir:status [ fhir:v "empty" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>[No data.]</p></div>"^^rdf:XMLLiteral ] ] [ fhir:title [ fhir:v "Effect Estimate" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "result-with-intervention-vs-comparator" ] ; fhir:display [ fhir:v "Result with intervention vs. comparator" ] ] ) ] ; fhir:text [ fhir:status [ fhir:v "generated" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>difference in means -4.5 mm Hg (95% confidence interval -10.82 mm Hg to 1.32 mm Hg)</p></div>"^^rdf:XMLLiteral ] ; ( fhir:entry [ fhir:reference [ fhir:v "Evidence/397483" ] ; fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ; fhir:display [ fhir:v "Evidence for Results for Systolic blood pressure at 12 weeks in GroupAssignment: Quadpill vs. Candesartan" ] ] ) ] [ fhir:title [ fhir:v "Certainty of Evidence" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "certainty-of-evidence" ] ; fhir:display [ fhir:v "Certainty of Evidence" ] ] ) ] ; fhir:text [ fhir:status [ fhir:v "empty" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>[No certainty rating found.]</p></div>"^^rdf:XMLLiteral ] ; ( fhir:entry [ fhir:reference [ fhir:v "Evidence/397483" ] ; fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ; fhir:display [ fhir:v "Evidence for Results for Systolic blood pressure at 12 weeks in GroupAssignment: Quadpill vs. Candesartan" ] ] ) ] [ fhir:title [ fhir:v "Assertion" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "assertion" ] ; fhir:display [ fhir:v "Assertion" ] ] ) ] ; fhir:text [ fhir:status [ fhir:v "empty" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>[No assertion provided.]</p></div>"^^rdf:XMLLiteral ] ; ( fhir:entry [ fhir:reference [ fhir:v "Evidence/397483" ] ; fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ; fhir:display [ fhir:v "Evidence for Results for Systolic blood pressure at 12 weeks in GroupAssignment: Quadpill vs. Candesartan" ] ] ) ] ) ] [ fhir:title [ fhir:v "Results for Diastolic blood pressure at 12 weeks" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; 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fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "sample-size" ] ; fhir:display [ fhir:v "Sample Size" ] ] ) ] ; fhir:text [ fhir:status [ fhir:v "generated" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>62 participants, 60 analyzed, 53 without missing data</p></div>"^^rdf:XMLLiteral ] ; ( fhir:entry [ fhir:reference [ fhir:v "Evidence/397482" ] ; fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ; fhir:display [ fhir:v "Evidence for Results for Diastolic blood pressure at 12 weeks in GroupAssignment: Quadpill vs. Candesartan" ] ] ) ] [ fhir:title [ fhir:v "Result Without Treatment" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "result-with-comparator-alone" ] ; fhir:display [ fhir:v "Result with comparator alone" ] ] ) ] ; fhir:text [ fhir:status [ fhir:v "empty" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>[Not a proportion.]</p></div>"^^rdf:XMLLiteral ] ; ( fhir:entry [ fhir:reference [ fhir:v "Evidence/375932" ] ; fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ; fhir:display [ fhir:v "Evidence for Results for Diastolic blood pressure at 12 weeks in QUARTET USA Trial Control Group" ] ] ) ] [ fhir:title [ fhir:v "Result With Treatment--Observed" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "result-with-intervention-alone" ] ; fhir:display [ fhir:v "Result with intervention alone" ] ] ) ] ; fhir:text [ fhir:status [ fhir:v "empty" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>[Not a proportion.]</p></div>"^^rdf:XMLLiteral ] ; ( fhir:entry [ fhir:reference [ fhir:v "Evidence/375629" ] ; fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ; fhir:display [ fhir:v "Evidence for Results for Diastolic blood pressure at 12 weeks in QUARTET USA Trial Quadpill group" ] ] ) ] [ fhir:title [ fhir:v "Result With Treatment--Derived" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "result-with-intervention-alone-calculated" ] ; fhir:display [ fhir:v "Result with intervention alone (calculated)" ] ] ) ; fhir:text [ fhir:v "result with intervention with calculated value derived from the control group and effect estimate" ] ] ; fhir:text [ fhir:status [ fhir:v "empty" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>[No data.]</p></div>"^^rdf:XMLLiteral ] ] [ fhir:title [ fhir:v "Effect Estimate" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "result-with-intervention-vs-comparator" ] ; fhir:display [ fhir:v "Result with intervention vs. comparator" ] ] ) ] ; fhir:text [ fhir:status [ fhir:v "generated" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>difference in means -4.92 mm Hg (95% confidence interval -8.58 mm Hg to 0.27 mm Hg)</p></div>"^^rdf:XMLLiteral ] ; ( fhir:entry [ fhir:reference [ fhir:v "Evidence/397482" ] ; fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ; fhir:display [ fhir:v "Evidence for Results for Diastolic blood pressure at 12 weeks in GroupAssignment: Quadpill vs. Candesartan" ] ] ) ] [ fhir:title [ fhir:v "Certainty of Evidence" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "certainty-of-evidence" ] ; fhir:display [ fhir:v "Certainty of Evidence" ] ] ) ] ; fhir:text [ fhir:status [ fhir:v "empty" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>[No certainty rating found.]</p></div>"^^rdf:XMLLiteral ] ; ( fhir:entry [ fhir:reference [ fhir:v "Evidence/397482" ] ; fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ; fhir:display [ fhir:v "Evidence for Results for Diastolic blood pressure at 12 weeks in GroupAssignment: Quadpill vs. Candesartan" ] ] ) ] [ fhir:title [ fhir:v "Assertion" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "assertion" ] ; fhir:display [ fhir:v "Assertion" ] ] ) ] ; fhir:text [ fhir:status [ fhir:v "empty" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>[No assertion provided.]</p></div>"^^rdf:XMLLiteral ] ; ( fhir:entry [ fhir:reference [ fhir:v "Evidence/397482" ] ; fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ; fhir:display [ fhir:v "Evidence for Results for Diastolic blood pressure at 12 weeks in GroupAssignment: Quadpill vs. Candesartan" ] ] ) ] ) ] [ fhir:title [ fhir:v "Results for Medication Adherence at 12 weeks" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "summary-of-findings-entry-for-a-single-outcome" ] ; fhir:display [ fhir:v "Summary of findings entry for a single outcome" ] ] ) ] ; fhir:focus [ fhir:reference [ fhir:v "EvidenceVariable/375201" ] ; fhir:type [ fhir:v "EvidenceVariable"^^xsd:anyURI ] ; fhir:display [ fhir:v "Medication Adherence at 12 weeks" ] ] ; fhir:text [ fhir:status [ fhir:v "empty" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>[No data.]</p></div>"^^rdf:XMLLiteral ] ; ( fhir:section [ fhir:title [ fhir:v "Outcome Measure" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "outcome-measure" ] ; fhir:display [ fhir:v "Outcome Measure" ] ] ) ] ; fhir:text [ fhir:status [ fhir:v "generated" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>Medication Adherence at 12 weeks</p></div>"^^rdf:XMLLiteral ] ; ( fhir:entry [ fhir:reference [ fhir:v "EvidenceVariable/375201" ] ; fhir:type [ fhir:v "EvidenceVariable"^^xsd:anyURI ] ; fhir:display [ fhir:v "Medication Adherence at 12 weeks" ] ] ) ] [ fhir:title [ fhir:v "Sample Size" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "sample-size" ] ; fhir:display [ fhir:v "Sample Size" ] ] ) ] ; fhir:text [ fhir:status [ fhir:v "generated" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>62 participants, 53 without missing data</p></div>"^^rdf:XMLLiteral ] ; ( fhir:entry [ fhir:reference [ fhir:v "Evidence/397481" ] ; fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ; fhir:display [ fhir:v "Evidence for Results for Medication Adherence at 12 weeks in GroupAssignment: Quadpill vs. Candesartan" ] ] ) ] [ fhir:title [ fhir:v "Result Without Treatment" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "result-with-comparator-alone" ] ; fhir:display [ fhir:v "Result with comparator alone" ] ] ) ] ; fhir:text [ fhir:status [ fhir:v "generated" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>70%</p></div>"^^rdf:XMLLiteral ] ; ( fhir:entry [ fhir:reference [ fhir:v "Evidence/379724" ] ; fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ; fhir:display [ fhir:v "Evidence for Results for Medication Adherence at 12 weeks in QUARTET USA Trial Control Group" ] ] ) ] [ fhir:title [ fhir:v "Result With Treatment--Observed" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "result-with-intervention-alone" ] ; fhir:display [ fhir:v "Result with intervention alone" ] ] ) ] ; fhir:text [ fhir:status [ fhir:v "generated" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>65.6%</p></div>"^^rdf:XMLLiteral ] ; ( fhir:entry [ fhir:reference [ fhir:v "Evidence/379723" ] ; fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ; fhir:display [ fhir:v "Evidence for Results for Medication Adherence at 12 weeks in QUARTET USA Trial Quadpill group" ] ] ) ] [ fhir:title [ fhir:v "Result With Treatment--Derived" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "result-with-intervention-alone-calculated" ] ; fhir:display [ fhir:v "Result with intervention alone (calculated)" ] ] ) ; fhir:text [ fhir:v "result with intervention with calculated value derived from the control group and effect estimate" ] ] ; fhir:text [ fhir:status [ fhir:v "empty" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>[No data.]</p></div>"^^rdf:XMLLiteral ] ] [ fhir:title [ fhir:v "Effect Estimate" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "result-with-intervention-vs-comparator" ] ; fhir:display [ fhir:v "Result with intervention vs. comparator" ] ] ) ] ; fhir:text [ fhir:status [ fhir:v "generated" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>odds ratio 0.37 (95% confidence interval 0.19 to 2.08)</p></div>"^^rdf:XMLLiteral ] ; ( fhir:entry [ fhir:reference [ fhir:v "Evidence/397481" ] ; fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ; fhir:display [ fhir:v "Evidence for Results for Medication Adherence at 12 weeks in GroupAssignment: Quadpill vs. Candesartan" ] ] ) ] [ fhir:title [ fhir:v "Certainty of Evidence" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "certainty-of-evidence" ] ; fhir:display [ fhir:v "Certainty of Evidence" ] ] ) ] ; fhir:text [ fhir:status [ fhir:v "empty" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>[No certainty rating found.]</p></div>"^^rdf:XMLLiteral ] ; ( fhir:entry [ fhir:reference [ fhir:v "Evidence/397481" ] ; fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ; fhir:display [ fhir:v "Evidence for Results for Medication Adherence at 12 weeks in GroupAssignment: Quadpill vs. Candesartan" ] ] ) ] [ fhir:title [ fhir:v "Assertion" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "assertion" ] ; fhir:display [ fhir:v "Assertion" ] ] ) ] ; fhir:text [ fhir:status [ fhir:v "empty" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>[No assertion provided.]</p></div>"^^rdf:XMLLiteral ] ; ( fhir:entry [ fhir:reference [ fhir:v "Evidence/397481" ] ; fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ; fhir:display [ fhir:v "Evidence for Results for Medication Adherence at 12 weeks in GroupAssignment: Quadpill vs. Candesartan" ] ] ) ] ) ] [ fhir:title [ fhir:v "Results for Hypertension Control at 12 weeks" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "summary-of-findings-entry-for-a-single-outcome" ] ; fhir:display [ fhir:v "Summary of findings entry for a single outcome" ] ] ) ] ; fhir:focus [ fhir:reference [ fhir:v "EvidenceVariable/375202" ] ; fhir:type [ fhir:v "EvidenceVariable"^^xsd:anyURI ] ; fhir:display [ fhir:v "Hypertension Control at 12 weeks" ] ] ; ( fhir:section [ fhir:title [ fhir:v "Outcome Measure" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "outcome-measure" ] ; fhir:display [ fhir:v "Outcome Measure" ] ] ) ] ; fhir:text [ fhir:status [ fhir:v "generated" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>Hypertension Control at 12 weeks</p></div>"^^rdf:XMLLiteral ] ; ( fhir:entry [ fhir:reference [ fhir:v "EvidenceVariable/375202" ] ; fhir:type [ fhir:v "EvidenceVariable"^^xsd:anyURI ] ; fhir:display [ fhir:v "Hypertension Control at 12 weeks" ] ] ) ] [ fhir:title [ fhir:v "Sample Size" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "sample-size" ] ; fhir:display [ fhir:v "Sample Size" ] ] ) ] ; fhir:text [ fhir:status [ fhir:v "generated" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>62 participants, 60 analyzed, 53 without missing data</p></div>"^^rdf:XMLLiteral ] ; ( fhir:entry [ fhir:reference [ fhir:v "Evidence/397480" ] ; fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ; fhir:display [ fhir:v "Evidence for Results for Hypertension Control at 12 weeks in GroupAssignment: Quadpill vs. Candesartan" ] ] ) ] [ fhir:title [ fhir:v "Result Without Treatment" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "result-with-comparator-alone" ] ; fhir:display [ fhir:v "Result with comparator alone" ] ] ) ] ; fhir:text [ fhir:status [ fhir:v "generated" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>54.17%</p></div>"^^rdf:XMLLiteral ] ; ( fhir:entry [ fhir:reference [ fhir:v "Evidence/379737" ] ; fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ; fhir:display [ fhir:v "Evidence for Results for Hypertension Control at 12 weeks in QUARTET USA Trial Control Group" ] ] ) ] [ fhir:title [ fhir:v "Result With Treatment--Observed" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "result-with-intervention-alone" ] ; fhir:display [ fhir:v "Result with intervention alone" ] ] ) ] ; fhir:text [ fhir:status [ fhir:v "generated" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>65.52%</p></div>"^^rdf:XMLLiteral ] ; ( fhir:entry [ fhir:reference [ fhir:v "Evidence/379736" ] ; fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ; fhir:display [ fhir:v "Evidence for Results for Hypertension Control at 12 weeks in QUARTET USA Trial Quadpill group" ] ] ) ] [ fhir:title [ fhir:v "Result With Treatment--Derived" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "result-with-intervention-alone-calculated" ] ; fhir:display [ fhir:v "Result with intervention alone (calculated)" ] ] ) ; fhir:text [ fhir:v "result with intervention with calculated value derived from the control group and effect estimate" ] ] ; fhir:text [ fhir:status [ fhir:v "empty" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>[No data.]</p></div>"^^rdf:XMLLiteral ] ] [ fhir:title [ fhir:v "Effect Estimate" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "result-with-intervention-vs-comparator" ] ; fhir:display [ fhir:v "Result with intervention vs. comparator" ] ] ) ] ; fhir:text [ fhir:status [ fhir:v "generated" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>odds ratio 2.85 (95% confidence interval 0.94 to 8.59)</p></div>"^^rdf:XMLLiteral ] ; ( fhir:entry [ fhir:reference [ fhir:v "Evidence/397480" ] ; fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ; fhir:display [ fhir:v "Evidence for Results for Hypertension Control at 12 weeks in GroupAssignment: Quadpill vs. Candesartan" ] ] ) ] [ fhir:title [ fhir:v "Certainty of Evidence" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "certainty-of-evidence" ] ; fhir:display [ fhir:v "Certainty of Evidence" ] ] ) ] ; fhir:text [ fhir:status [ fhir:v "empty" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>[No certainty rating found.]</p></div>"^^rdf:XMLLiteral ] ; ( fhir:entry [ fhir:reference [ fhir:v "Evidence/397480" ] ; fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ; fhir:display [ fhir:v "Evidence for Results for Hypertension Control at 12 weeks in GroupAssignment: Quadpill vs. Candesartan" ] ] ) ] [ fhir:title [ fhir:v "Assertion" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "assertion" ] ; fhir:display [ fhir:v "Assertion" ] ] ) ] ; fhir:text [ fhir:status [ fhir:v "empty" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>[No assertion provided.]</p></div>"^^rdf:XMLLiteral ] ; ( fhir:entry [ fhir:reference [ fhir:v "Evidence/397480" ] ; fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ; fhir:display [ fhir:v "Evidence for Results for Hypertension Control at 12 weeks in GroupAssignment: Quadpill vs. Candesartan" ] ] ) ] ) ] [ fhir:title [ fhir:v "Results for Add-on Amlodipine at 6 weeks" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "summary-of-findings-entry-for-a-single-outcome" ] ; fhir:display [ fhir:v "Summary of findings entry for a single outcome" ] ] ) ] ; fhir:focus [ fhir:reference [ fhir:v "EvidenceVariable/375203" ] ; fhir:type [ fhir:v "EvidenceVariable"^^xsd:anyURI ] ; fhir:display [ fhir:v "Add-on Amlodipine at 6 weeks" ] ] ; ( fhir:section [ fhir:title [ fhir:v "Outcome Measure" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "outcome-measure" ] ; fhir:display [ fhir:v "Outcome Measure" ] ] ) ] ; fhir:text [ fhir:status [ fhir:v "generated" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>Add-on Amlodipine at 6 weeks</p></div>"^^rdf:XMLLiteral ] ; ( fhir:entry [ fhir:reference [ fhir:v "EvidenceVariable/375203" ] ; fhir:type [ fhir:v "EvidenceVariable"^^xsd:anyURI ] ; fhir:display [ fhir:v "Add-on Amlodipine at 6 weeks" ] ] ) ] [ fhir:title [ fhir:v "Sample Size" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "sample-size" ] ; fhir:display [ fhir:v "Sample Size" ] ] ) ] ; fhir:text [ fhir:status [ fhir:v "generated" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>62 participants, 60 analyzed, 62 without missing data, 22 events</p></div>"^^rdf:XMLLiteral ] ; ( fhir:entry [ fhir:reference [ fhir:v "Evidence/397479" ] ; fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ; fhir:display [ fhir:v "Evidence for Results for Add-on Amlodipine at 6 weeks in GroupAssignment: Quadpill vs. Candesartan" ] ] ) ] [ fhir:title [ fhir:v "Result Without Treatment" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "result-with-comparator-alone" ] ; fhir:display [ fhir:v "Result with comparator alone" ] ] ) ] ; fhir:text [ fhir:status [ fhir:v "generated" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>53.33%</p></div>"^^rdf:XMLLiteral ] ; ( fhir:entry [ fhir:reference [ fhir:v "Evidence/379740" ] ; fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ; fhir:display [ fhir:v "Evidence for Results for Add-on Amlodipine at 6 weeks in QUARTET USA Trial Control Group" ] ] ) ] [ fhir:title [ fhir:v "Result With Treatment--Observed" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "result-with-intervention-alone" ] ; fhir:display [ fhir:v "Result with intervention alone" ] ] ) ] ; fhir:text [ fhir:status [ fhir:v "generated" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>18.75%</p></div>"^^rdf:XMLLiteral ] ; ( fhir:entry [ fhir:reference [ fhir:v "Evidence/379739" ] ; fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ; fhir:display [ fhir:v "Evidence for Results for Add-on Amlodipine at 6 weeks in QUARTET USA Trial Quadpill group" ] ] ) ] [ fhir:title [ fhir:v "Result With Treatment--Derived" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "result-with-intervention-alone-calculated" ] ; fhir:display [ fhir:v "Result with intervention alone (calculated)" ] ] ) ; fhir:text [ fhir:v "result with intervention with calculated value derived from the control group and effect estimate" ] ] ; fhir:text [ fhir:status [ fhir:v "empty" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>[No data.]</p></div>"^^rdf:XMLLiteral ] ] [ fhir:title [ fhir:v "Effect Estimate" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "result-with-intervention-vs-comparator" ] ; fhir:display [ fhir:v "Result with intervention vs. comparator" ] ] ) ] ; fhir:text [ fhir:status [ fhir:v "generated" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>odds ratio 0.92 (95% confidence interval 0.02 to 0.41)</p></div>"^^rdf:XMLLiteral ] ; ( fhir:entry [ fhir:reference [ fhir:v "Evidence/397479" ] ; fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ; fhir:display [ fhir:v "Evidence for Results for Add-on Amlodipine at 6 weeks in GroupAssignment: Quadpill vs. Candesartan" ] ] ) ] [ fhir:title [ fhir:v "Certainty of Evidence" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "certainty-of-evidence" ] ; fhir:display [ fhir:v "Certainty of Evidence" ] ] ) ] ; fhir:text [ fhir:status [ fhir:v "empty" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>[No certainty rating found.]</p></div>"^^rdf:XMLLiteral ] ; ( fhir:entry [ fhir:reference [ fhir:v "Evidence/397479" ] ; fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ; fhir:display [ fhir:v "Evidence for Results for Add-on Amlodipine at 6 weeks in GroupAssignment: Quadpill vs. Candesartan" ] ] ) ] [ fhir:title [ fhir:v "Assertion" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "assertion" ] ; fhir:display [ fhir:v "Assertion" ] ] ) ] ; fhir:text [ fhir:status [ fhir:v "empty" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>[No assertion provided.]</p></div>"^^rdf:XMLLiteral ] ; ( fhir:entry [ fhir:reference [ fhir:v "Evidence/397479" ] ; fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ; fhir:display [ fhir:v "Evidence for Results for Add-on Amlodipine at 6 weeks in GroupAssignment: Quadpill vs. Candesartan" ] ] ) ] ) ] [ fhir:title [ fhir:v "Results for Adverse event free and hypertension control at 12 weeks" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "summary-of-findings-entry-for-a-single-outcome" ] ; fhir:display [ fhir:v "Summary of findings entry for a single outcome" ] ] ) ] ; fhir:focus [ fhir:reference [ fhir:v "EvidenceVariable/375278" ] ; fhir:type [ fhir:v "EvidenceVariable"^^xsd:anyURI ] ; fhir:display [ fhir:v "Adverse event free and hypertension control at 12 weeks" ] ] ; ( fhir:section [ fhir:title [ fhir:v "Outcome Measure" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "outcome-measure" ] ; fhir:display [ fhir:v "Outcome Measure" ] ] ) ] ; fhir:text [ fhir:status [ fhir:v "generated" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>Adverse event free and hypertension control at 12 weeks</p></div>"^^rdf:XMLLiteral ] ; ( fhir:entry [ fhir:reference [ fhir:v "EvidenceVariable/375278" ] ; fhir:type [ fhir:v "EvidenceVariable"^^xsd:anyURI ] ; fhir:display [ fhir:v "Adverse event free and hypertension control at 12 weeks" ] ] ) ] [ fhir:title [ fhir:v "Sample Size" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "sample-size" ] ; fhir:display [ fhir:v "Sample Size" ] ] ) ] ; fhir:text [ fhir:status [ fhir:v "generated" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>62 participants, 53 analyzed, 53 without missing data, 13 events</p></div>"^^rdf:XMLLiteral ] ; ( fhir:entry [ fhir:reference [ fhir:v "Evidence/397478" ] ; fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ; fhir:display [ fhir:v "Evidence for Results for Adverse event free and hypertension control at 12 weeks in GroupAssignment: Quadpill vs. Candesartan" ] ] ) ] [ fhir:title [ fhir:v "Result Without Treatment" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "result-with-comparator-alone" ] ; fhir:display [ fhir:v "Result with comparator alone" ] ] ) ] ; fhir:text [ fhir:status [ fhir:v "generated" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>33.33%</p></div>"^^rdf:XMLLiteral ] ; ( fhir:entry [ fhir:reference [ fhir:v "Evidence/379743" ] ; fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ; fhir:display [ fhir:v "Evidence for Results for Adverse event free and hypertension control at 12 weeks in QUARTET USA Trial Control Group" ] ] ) ] [ fhir:title [ fhir:v "Result With Treatment--Observed" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "result-with-intervention-alone" ] ; fhir:display [ fhir:v "Result with intervention alone" ] ] ) ] ; fhir:text [ fhir:status [ fhir:v "generated" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>17.24%</p></div>"^^rdf:XMLLiteral ] ; ( fhir:entry [ fhir:reference [ fhir:v "Evidence/379742" ] ; fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ; fhir:display [ fhir:v "Evidence for Results for Adverse event free and hypertension control at 12 weeks in QUARTET USA Trial Quadpill group" ] ] ) ] [ fhir:title [ fhir:v "Result With Treatment--Derived" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "result-with-intervention-alone-calculated" ] ; fhir:display [ fhir:v "Result with intervention alone (calculated)" ] ] ) ; fhir:text [ fhir:v "result with intervention with calculated value derived from the control group and effect estimate" ] ] ; fhir:text [ fhir:status [ fhir:v "empty" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>[No data.]</p></div>"^^rdf:XMLLiteral ] ] [ fhir:title [ fhir:v "Effect Estimate" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "result-with-intervention-vs-comparator" ] ; fhir:display [ fhir:v "Result with intervention vs. comparator" ] ] ) ] ; fhir:text [ fhir:status [ fhir:v "generated" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>odds ratio 0.83 (95% confidence interval 0.22 to 3.16)</p></div>"^^rdf:XMLLiteral ] ; ( fhir:entry [ fhir:reference [ fhir:v "Evidence/397478" ] ; fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ; fhir:display [ fhir:v "Evidence for Results for Adverse event free and hypertension control at 12 weeks in GroupAssignment: Quadpill vs. Candesartan" ] ] ) ] [ fhir:title [ fhir:v "Certainty of Evidence" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "certainty-of-evidence" ] ; fhir:display [ fhir:v "Certainty of Evidence" ] ] ) ] ; fhir:text [ fhir:status [ fhir:v "empty" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>[No certainty rating found.]</p></div>"^^rdf:XMLLiteral ] ; ( fhir:entry [ fhir:reference [ fhir:v "Evidence/397478" ] ; fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ; fhir:display [ fhir:v "Evidence for Results for Adverse event free and hypertension control at 12 weeks in GroupAssignment: Quadpill vs. Candesartan" ] ] ) ] [ fhir:title [ fhir:v "Assertion" ] ; fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ; fhir:code [ fhir:v "assertion" ] ; fhir:display [ fhir:v "Assertion" ] ] ) ] ; fhir:text [ fhir:status [ fhir:v "empty" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>[No assertion provided.]</p></div>"^^rdf:XMLLiteral ] ; ( fhir:entry [ fhir:reference [ fhir:v "Evidence/397478" ] ; fhir:type [ fhir:v "Evidence"^^xsd:anyURI ] ; fhir:display [ fhir:v "Evidence for Results for Adverse event free and hypertension control at 12 weeks in GroupAssignment: Quadpill vs. Candesartan" ] ] ) ] ) ] ) ] ) . #
IG © 2024+ HL7 International / Clinical Decision Support. Package hl7.fhir.uv.ebm#1.0.0-ballot2 based on FHIR 6.0.0-ballot3. Generated 2025-09-13
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