Evidence Based Medicine on FHIR Implementation Guide
2.0.0-ballot - ballot International flag

Evidence Based Medicine on FHIR Implementation Guide, published by HL7 International / Clinical Decision Support. This guide is not an authorized publication; it is the continuous build for version 2.0.0-ballot built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/ebm/ and changes regularly. See the Directory of published versions

Resource Profile: ParticipantFlowEvidence

Official URL: http://hl7.org/fhir/uv/ebm/StructureDefinition/participant-flow-evidence Version: 2.0.0-ballot
Standards status: Draft Maturity Level: 1 Computable Name: ParticipantFlowEvidence
Other Identifiers: OID:2.16.840.1.113883.4.642.40.44.42.73

Profile of Evidence for Evidence Based Medicine IG. The ParticipantFlowEvidence Profile is used for counts of completion and reasons for non-completion of participation in a research study.

Usage:

Formal Views of Profile Content

Description of Profiles, Differentials, Snapshots and how the different presentations work.

This structure is derived from NonComparativeEvidence

NameFlagsCard.TypeDescription & Constraintsdoco
.. Evidence NonComparativeEvidence
... variableDefinition 2..* BackboneElement Evidence variable such as population, exposure, or outcome
.... intended 0..0
.... directnessMatch 0..0
... Slices for variableDefinition Content/Rules for all slices
.... variableDefinition:population 1..* BackboneElement Evidence variable such as population, exposure, or outcome
..... intended 0..0
..... directnessMatch 0..0
.... variableDefinition:outcome 1..* BackboneElement Evidence variable such as population, exposure, or outcome
..... observed 0..1 Reference(ParticipantFlowEvidenceVariable) Definition of the actual variable related to the statistic(s)
..... intended 0..0
..... directnessMatch 0..0
... statistic
.... numberAffected 0..0
.... modelCharacteristic 0..0

doco Documentation for this format
NameFlagsCard.TypeDescription & Constraintsdoco
.. Evidence C 0..* NonComparativeEvidence Single evidence bit
cnl-0: Name should be usable as an identifier for the module by machine processing applications such as code generation
... implicitRules ?!Σ 0..1 uri A set of rules under which this content was created
... contained 0..* Resource Contained, inline Resources
... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored
... Slices for variableDefinition 2..* BackboneElement Evidence variable such as population, exposure, or outcome
Slice: Unordered, Open by value:variableRole
.... variableDefinition:All Slices Content/Rules for all slices
..... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
..... variableRole Σ 1..1 code population | exposure | outcome | covariate
Binding: EvidenceVariableRole (required): The role that the variable plays.

.... variableDefinition:population S 1..* BackboneElement Evidence variable such as population, exposure, or outcome
..... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
..... variableRole Σ 1..1 code population | exposure | outcome | covariate
Binding: EvidenceVariableRole (required): The role that the variable plays.


Required Pattern: population
.... variableDefinition:outcome S 1..* BackboneElement Evidence variable such as population, exposure, or outcome
..... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
..... variableRole Σ 1..1 code population | exposure | outcome | covariate
Binding: EvidenceVariableRole (required): The role that the variable plays.


Required Pattern: outcome
..... observed Σ 0..1 Reference(ParticipantFlowEvidenceVariable) Definition of the actual variable related to the statistic(s)

doco Documentation for this format

Terminology Bindings

PathConformanceValueSet / CodeURI
Evidence.statusrequiredPublicationStatus
http://hl7.org/fhir/ValueSet/publication-status|6.0.0-ballot2
from the FHIR Standard
Evidence.variableDefinition.variableRolerequiredEvidenceVariableRole
http://hl7.org/fhir/ValueSet/variable-role|6.0.0-ballot2
from the FHIR Standard
Evidence.variableDefinition:population.variableRolerequiredPattern: population
http://hl7.org/fhir/ValueSet/variable-role|6.0.0-ballot2
from the FHIR Standard
Evidence.variableDefinition:outcome.variableRolerequiredPattern: outcome
http://hl7.org/fhir/ValueSet/variable-role|6.0.0-ballot2
from the FHIR Standard

Constraints

IdGradePath(s)DetailsRequirements
cnl-0warningEvidenceName should be usable as an identifier for the module by machine processing applications such as code generation
: name.exists() implies name.matches('^[A-Z]([A-Za-z0-9_]){1,254}$')
ele-1error**ALL** elementsAll FHIR elements must have a @value or children
: hasValue() or (children().count() > id.count())
NameFlagsCard.TypeDescription & Constraintsdoco
.. Evidence C 0..* NonComparativeEvidence Single evidence bit
cnl-0: Name should be usable as an identifier for the module by machine processing applications such as code generation
... id Σ 0..1 id Logical id of this artifact
... meta Σ 0..1 Meta Metadata about the resource
... implicitRules ?!Σ 0..1 uri A set of rules under which this content was created
... language 0..1 code Language of the resource content
Binding: AllLanguages (required): IETF language tag for a human language

Additional BindingsPurpose
CommonLanguages Starter Set
... text 0..1 Narrative Text summary of the resource, for human interpretation
... contained 0..* Resource Contained, inline Resources
... extension 0..* Extension Additional content defined by implementations
... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored
... url ΣC 0..1 uri Canonical identifier for this evidence, represented as a globally unique URI
cnl-1: URL should not contain | or # - these characters make processing canonical references problematic
... identifier Σ 0..* Identifier Additional identifier for the summary
... version Σ 0..1 string Business version of this summary
... versionAlgorithm[x] Σ 0..1 How to compare versions
Binding: VersionAlgorithm (extensible)
.... versionAlgorithmString string
.... versionAlgorithmCoding Coding
... name C 0..1 string Name for this summary (machine friendly)
... title Σ 0..1 string Name for this summary (human friendly)
... citeAs[x] 0..1 Citation for this evidence
.... citeAsReference Reference(Citation)
.... citeAsMarkdown markdown
... status ?!Σ 1..1 code draft | active | retired | unknown
Binding: PublicationStatus (required): The lifecycle status of an artifact.

... experimental 0..1 boolean For testing purposes, not real usage
... date Σ 0..1 dateTime Date last changed
... approvalDate 0..1 date When the summary was approved by publisher
... lastReviewDate 0..1 date When the summary was last reviewed by the publisher
... publisher Σ 0..1 string Name of the publisher/steward (organization or individual)
... contact Σ 0..* ContactDetail Contact details for the publisher
... author Σ 0..* ContactDetail Who authored the content
... editor 0..* ContactDetail Who edited the content
... reviewer 0..* ContactDetail Who reviewed the content
... endorser Σ 0..* ContactDetail Who endorsed the content
... useContext Σ 0..* UsageContext The context that the content is intended to support
... purpose 0..1 markdown Why this Evidence is defined
... copyright 0..1 markdown Use and/or publishing restrictions
... copyrightLabel 0..1 string Copyright holder and year(s)
... relatedArtifact 0..* RelatedArtifact Link or citation to artifact associated with the summary
... description 0..1 markdown Description of the particular summary
... assertion 0..1 markdown Declarative description of the Evidence
... note 0..* Annotation Footnotes and/or explanatory notes
... Slices for variableDefinition 2..* BackboneElement Evidence variable such as population, exposure, or outcome
Slice: Unordered, Open by value:variableRole
.... variableDefinition:All Slices Content/Rules for all slices
..... id 0..1 string Unique id for inter-element referencing
..... extension 0..* Extension Additional content defined by implementations
..... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
..... description 0..1 markdown A text description or summary of the variable
..... note 0..* Annotation Footnotes and/or explanatory notes
..... variableRole Σ 1..1 code population | exposure | outcome | covariate
Binding: EvidenceVariableRole (required): The role that the variable plays.

..... roleSubtype Σ 0..1 CodeableConcept subgroup | variable-A | variable-B | variable-AB | confounder | collider | mediator | effect-modifier
Binding: EvidenceVariableRoleSubtype (extensible): The sub-role that the variable plays.

..... comparatorCategory 0..1 string The reference value used for comparison
..... observed Σ 0..1 Reference(Group | EvidenceVariable) Definition of the actual variable related to the statistic(s)
.... variableDefinition:population S 1..* BackboneElement Evidence variable such as population, exposure, or outcome
..... id 0..1 string Unique id for inter-element referencing
..... extension 0..* Extension Additional content defined by implementations
..... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
..... description 0..1 markdown A text description or summary of the variable
..... note 0..* Annotation Footnotes and/or explanatory notes
..... variableRole Σ 1..1 code population | exposure | outcome | covariate
Binding: EvidenceVariableRole (required): The role that the variable plays.


Required Pattern: population
..... roleSubtype Σ 0..1 CodeableConcept subgroup | variable-A | variable-B | variable-AB | confounder | collider | mediator | effect-modifier
Binding: EvidenceVariableRoleSubtype (extensible): The sub-role that the variable plays.

..... comparatorCategory 0..1 string The reference value used for comparison
..... observed Σ 0..1 Reference(StudyGroup | ExposureGroup | ComparatorGroup | MetaanalysisStudyGroup) Definition of the actual variable related to the statistic(s)
.... variableDefinition:outcome S 1..* BackboneElement Evidence variable such as population, exposure, or outcome
..... id 0..1 string Unique id for inter-element referencing
..... extension 0..* Extension Additional content defined by implementations
..... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
..... description 0..1 markdown A text description or summary of the variable
..... note 0..* Annotation Footnotes and/or explanatory notes
..... variableRole Σ 1..1 code population | exposure | outcome | covariate
Binding: EvidenceVariableRole (required): The role that the variable plays.


Required Pattern: outcome
..... roleSubtype Σ 0..1 CodeableConcept subgroup | variable-A | variable-B | variable-AB | confounder | collider | mediator | effect-modifier
Binding: EvidenceVariableRoleSubtype (extensible): The sub-role that the variable plays.

..... comparatorCategory 0..1 string The reference value used for comparison
..... observed Σ 0..1 Reference(ParticipantFlowEvidenceVariable) Definition of the actual variable related to the statistic(s)
... synthesisType 0..1 CodeableConcept The method to combine studies
Binding: StatisticSynthesisType (extensible): Types of combining results from a body of evidence (e.g. summary data meta-analysis).

... studyDesign 0..* CodeableConcept The design of the study that produced this evidence
Binding: StudyDesign (extensible): This is a set of terms for study design characteristics.


... statistic 0..* BackboneElement Values and parameters for a single statistic
.... id 0..1 string Unique id for inter-element referencing
.... extension 0..* Extension Additional content defined by implementations
.... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
.... description 0..1 markdown Description of content
.... note 0..* Annotation Footnotes and/or explanatory notes
.... statisticType 0..1 CodeableConcept Type of statistic, e.g., relative risk
Binding: StatisticType (extensible)
.... category 0..1 CodeableConcept Associated category for categorical variable
.... quantity 0..1 Quantity Statistic value
.... numberOfEvents 0..1 unsignedInt The number of events associated with the statistic
.... sampleSize 0..1 BackboneElement Number of samples in the statistic
..... id 0..1 string Unique id for inter-element referencing
..... extension 0..* Extension Additional content defined by implementations
..... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
..... description 0..1 markdown Textual description of sample size for statistic
..... note 0..* Annotation Footnote or explanatory note about the sample size
..... numberOfStudies 0..1 unsignedInt Number of contributing studies
..... numberOfParticipants 0..1 unsignedInt Cumulative number of participants
..... knownDataCount 0..1 unsignedInt Number of participants with known results for measured variables
.... attributeEstimate 0..* BackboneElement An attribute of the Statistic
..... id 0..1 string Unique id for inter-element referencing
..... extension 0..* Extension Additional content defined by implementations
..... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
..... description 0..1 markdown Textual description of the attribute estimate
..... note 0..* Annotation Footnote or explanatory note about the estimate
..... type 0..1 CodeableConcept The type of attribute estimate, e.g., confidence interval or p value
Binding: AttributeEstimateType (extensible)
..... quantity 0..1 Quantity The singular quantity of the attribute estimate, for attribute estimates represented as single values; also used to report unit of measure
..... level 0..1 decimal Level of confidence interval, e.g., 0.95 for 95% confidence interval
..... range 0..1 Range Lower and upper bound values of the attribute estimate
..... attributeEstimate 0..* See attributeEstimate (Evidence) A nested attribute estimate; which is the attribute estimate of an attribute estimate
... certainty 0..* BackboneElement Certainty or quality of the evidence
.... id 0..1 string Unique id for inter-element referencing
.... extension 0..* Extension Additional content defined by implementations
.... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
.... description 0..1 markdown Textual description of certainty
.... note 0..* Annotation Footnotes and/or explanatory notes
.... type 0..1 CodeableConcept Aspect of certainty being rated
Binding: EvidenceCertaintyType (extensible): The aspect of quality, confidence, or certainty.

.... rating 0..1 CodeableConcept Assessment or judgement of the aspect
Binding: EvidenceCertaintyRating (extensible): The assessment of quality, confidence, or certainty.

.... rater 0..1 string Individual or group who did the rating
.... subcomponent 0..* See certainty (Evidence) A domain or subdomain of certainty

doco Documentation for this format

Terminology Bindings

PathConformanceValueSet / CodeURI
Evidence.languagerequiredAllLanguages
http://hl7.org/fhir/ValueSet/all-languages|6.0.0-ballot2
from the FHIR Standard
Evidence.versionAlgorithm[x]extensibleVersionAlgorithm
http://hl7.org/fhir/ValueSet/version-algorithm
from the FHIR Standard
Evidence.statusrequiredPublicationStatus
http://hl7.org/fhir/ValueSet/publication-status|6.0.0-ballot2
from the FHIR Standard
Evidence.variableDefinition.variableRolerequiredEvidenceVariableRole
http://hl7.org/fhir/ValueSet/variable-role|6.0.0-ballot2
from the FHIR Standard
Evidence.variableDefinition.roleSubtypeextensibleEvidenceVariableRoleSubtype
http://hl7.org/fhir/ValueSet/variable-role-subtype
from the FHIR Standard
Evidence.variableDefinition:population.variableRolerequiredPattern: population
http://hl7.org/fhir/ValueSet/variable-role|6.0.0-ballot2
from the FHIR Standard
Evidence.variableDefinition:population.roleSubtypeextensibleEvidenceVariableRoleSubtype
http://hl7.org/fhir/ValueSet/variable-role-subtype
from the FHIR Standard
Evidence.variableDefinition:outcome.variableRolerequiredPattern: outcome
http://hl7.org/fhir/ValueSet/variable-role|6.0.0-ballot2
from the FHIR Standard
Evidence.variableDefinition:outcome.roleSubtypeextensibleEvidenceVariableRoleSubtype
http://hl7.org/fhir/ValueSet/variable-role-subtype
from the FHIR Standard
Evidence.synthesisTypeextensibleStatisticSynthesisType
http://terminology.hl7.org/ValueSet/synthesis-type
Evidence.studyDesignextensibleStudyDesign
http://hl7.org/fhir/ValueSet/study-design
from the FHIR Standard
Evidence.statistic.statisticTypeextensibleStatisticType
http://hl7.org/fhir/ValueSet/statistic-type
from the FHIR Standard
Evidence.statistic.attributeEstimate.typeextensibleAttributeEstimateType
http://hl7.org/fhir/ValueSet/attribute-estimate-type
from the FHIR Standard
Evidence.statistic.modelCharacteristic.codeextensibleStatisticModelCode
http://hl7.org/fhir/ValueSet/statistic-model-code
from the FHIR Standard
Evidence.statistic.modelCharacteristic.variable.handlingrequiredEvidenceVariableHandling
http://hl7.org/fhir/ValueSet/variable-handling|6.0.0-ballot2
from the FHIR Standard
Evidence.certainty.typeextensibleEvidenceCertaintyType
http://hl7.org/fhir/ValueSet/certainty-type
from the FHIR Standard
Evidence.certainty.ratingextensibleEvidenceCertaintyRating
http://hl7.org/fhir/ValueSet/certainty-rating
from the FHIR Standard

Constraints

IdGradePath(s)DetailsRequirements
cnl-0warningEvidenceName should be usable as an identifier for the module by machine processing applications such as code generation
: name.exists() implies name.matches('^[A-Z]([A-Za-z0-9_]){1,254}$')
cnl-1warningEvidence.urlURL should not contain | or # - these characters make processing canonical references problematic
: exists() implies matches('^[^|# ]+$')
ele-1error**ALL** elementsAll FHIR elements must have a @value or children
: hasValue() or (children().count() > id.count())

This structure is derived from NonComparativeEvidence

Summary

Prohibited: 8 elements

Structures

This structure refers to these other structures:

Maturity: 1

Differential View

This structure is derived from NonComparativeEvidence

NameFlagsCard.TypeDescription & Constraintsdoco
.. Evidence NonComparativeEvidence
... variableDefinition 2..* BackboneElement Evidence variable such as population, exposure, or outcome
.... intended 0..0
.... directnessMatch 0..0
... Slices for variableDefinition Content/Rules for all slices
.... variableDefinition:population 1..* BackboneElement Evidence variable such as population, exposure, or outcome
..... intended 0..0
..... directnessMatch 0..0
.... variableDefinition:outcome 1..* BackboneElement Evidence variable such as population, exposure, or outcome
..... observed 0..1 Reference(ParticipantFlowEvidenceVariable) Definition of the actual variable related to the statistic(s)
..... intended 0..0
..... directnessMatch 0..0
... statistic
.... numberAffected 0..0
.... modelCharacteristic 0..0

doco Documentation for this format

Key Elements View

NameFlagsCard.TypeDescription & Constraintsdoco
.. Evidence C 0..* NonComparativeEvidence Single evidence bit
cnl-0: Name should be usable as an identifier for the module by machine processing applications such as code generation
... implicitRules ?!Σ 0..1 uri A set of rules under which this content was created
... contained 0..* Resource Contained, inline Resources
... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored
... Slices for variableDefinition 2..* BackboneElement Evidence variable such as population, exposure, or outcome
Slice: Unordered, Open by value:variableRole
.... variableDefinition:All Slices Content/Rules for all slices
..... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
..... variableRole Σ 1..1 code population | exposure | outcome | covariate
Binding: EvidenceVariableRole (required): The role that the variable plays.

.... variableDefinition:population S 1..* BackboneElement Evidence variable such as population, exposure, or outcome
..... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
..... variableRole Σ 1..1 code population | exposure | outcome | covariate
Binding: EvidenceVariableRole (required): The role that the variable plays.


Required Pattern: population
.... variableDefinition:outcome S 1..* BackboneElement Evidence variable such as population, exposure, or outcome
..... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
..... variableRole Σ 1..1 code population | exposure | outcome | covariate
Binding: EvidenceVariableRole (required): The role that the variable plays.


Required Pattern: outcome
..... observed Σ 0..1 Reference(ParticipantFlowEvidenceVariable) Definition of the actual variable related to the statistic(s)

doco Documentation for this format

Terminology Bindings

PathConformanceValueSet / CodeURI
Evidence.statusrequiredPublicationStatus
http://hl7.org/fhir/ValueSet/publication-status|6.0.0-ballot2
from the FHIR Standard
Evidence.variableDefinition.variableRolerequiredEvidenceVariableRole
http://hl7.org/fhir/ValueSet/variable-role|6.0.0-ballot2
from the FHIR Standard
Evidence.variableDefinition:population.variableRolerequiredPattern: population
http://hl7.org/fhir/ValueSet/variable-role|6.0.0-ballot2
from the FHIR Standard
Evidence.variableDefinition:outcome.variableRolerequiredPattern: outcome
http://hl7.org/fhir/ValueSet/variable-role|6.0.0-ballot2
from the FHIR Standard

Constraints

IdGradePath(s)DetailsRequirements
cnl-0warningEvidenceName should be usable as an identifier for the module by machine processing applications such as code generation
: name.exists() implies name.matches('^[A-Z]([A-Za-z0-9_]){1,254}$')
ele-1error**ALL** elementsAll FHIR elements must have a @value or children
: hasValue() or (children().count() > id.count())

Snapshot View

NameFlagsCard.TypeDescription & Constraintsdoco
.. Evidence C 0..* NonComparativeEvidence Single evidence bit
cnl-0: Name should be usable as an identifier for the module by machine processing applications such as code generation
... id Σ 0..1 id Logical id of this artifact
... meta Σ 0..1 Meta Metadata about the resource
... implicitRules ?!Σ 0..1 uri A set of rules under which this content was created
... language 0..1 code Language of the resource content
Binding: AllLanguages (required): IETF language tag for a human language

Additional BindingsPurpose
CommonLanguages Starter Set
... text 0..1 Narrative Text summary of the resource, for human interpretation
... contained 0..* Resource Contained, inline Resources
... extension 0..* Extension Additional content defined by implementations
... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored
... url ΣC 0..1 uri Canonical identifier for this evidence, represented as a globally unique URI
cnl-1: URL should not contain | or # - these characters make processing canonical references problematic
... identifier Σ 0..* Identifier Additional identifier for the summary
... version Σ 0..1 string Business version of this summary
... versionAlgorithm[x] Σ 0..1 How to compare versions
Binding: VersionAlgorithm (extensible)
.... versionAlgorithmString string
.... versionAlgorithmCoding Coding
... name C 0..1 string Name for this summary (machine friendly)
... title Σ 0..1 string Name for this summary (human friendly)
... citeAs[x] 0..1 Citation for this evidence
.... citeAsReference Reference(Citation)
.... citeAsMarkdown markdown
... status ?!Σ 1..1 code draft | active | retired | unknown
Binding: PublicationStatus (required): The lifecycle status of an artifact.

... experimental 0..1 boolean For testing purposes, not real usage
... date Σ 0..1 dateTime Date last changed
... approvalDate 0..1 date When the summary was approved by publisher
... lastReviewDate 0..1 date When the summary was last reviewed by the publisher
... publisher Σ 0..1 string Name of the publisher/steward (organization or individual)
... contact Σ 0..* ContactDetail Contact details for the publisher
... author Σ 0..* ContactDetail Who authored the content
... editor 0..* ContactDetail Who edited the content
... reviewer 0..* ContactDetail Who reviewed the content
... endorser Σ 0..* ContactDetail Who endorsed the content
... useContext Σ 0..* UsageContext The context that the content is intended to support
... purpose 0..1 markdown Why this Evidence is defined
... copyright 0..1 markdown Use and/or publishing restrictions
... copyrightLabel 0..1 string Copyright holder and year(s)
... relatedArtifact 0..* RelatedArtifact Link or citation to artifact associated with the summary
... description 0..1 markdown Description of the particular summary
... assertion 0..1 markdown Declarative description of the Evidence
... note 0..* Annotation Footnotes and/or explanatory notes
... Slices for variableDefinition 2..* BackboneElement Evidence variable such as population, exposure, or outcome
Slice: Unordered, Open by value:variableRole
.... variableDefinition:All Slices Content/Rules for all slices
..... id 0..1 string Unique id for inter-element referencing
..... extension 0..* Extension Additional content defined by implementations
..... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
..... description 0..1 markdown A text description or summary of the variable
..... note 0..* Annotation Footnotes and/or explanatory notes
..... variableRole Σ 1..1 code population | exposure | outcome | covariate
Binding: EvidenceVariableRole (required): The role that the variable plays.

..... roleSubtype Σ 0..1 CodeableConcept subgroup | variable-A | variable-B | variable-AB | confounder | collider | mediator | effect-modifier
Binding: EvidenceVariableRoleSubtype (extensible): The sub-role that the variable plays.

..... comparatorCategory 0..1 string The reference value used for comparison
..... observed Σ 0..1 Reference(Group | EvidenceVariable) Definition of the actual variable related to the statistic(s)
.... variableDefinition:population S 1..* BackboneElement Evidence variable such as population, exposure, or outcome
..... id 0..1 string Unique id for inter-element referencing
..... extension 0..* Extension Additional content defined by implementations
..... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
..... description 0..1 markdown A text description or summary of the variable
..... note 0..* Annotation Footnotes and/or explanatory notes
..... variableRole Σ 1..1 code population | exposure | outcome | covariate
Binding: EvidenceVariableRole (required): The role that the variable plays.


Required Pattern: population
..... roleSubtype Σ 0..1 CodeableConcept subgroup | variable-A | variable-B | variable-AB | confounder | collider | mediator | effect-modifier
Binding: EvidenceVariableRoleSubtype (extensible): The sub-role that the variable plays.

..... comparatorCategory 0..1 string The reference value used for comparison
..... observed Σ 0..1 Reference(StudyGroup | ExposureGroup | ComparatorGroup | MetaanalysisStudyGroup) Definition of the actual variable related to the statistic(s)
.... variableDefinition:outcome S 1..* BackboneElement Evidence variable such as population, exposure, or outcome
..... id 0..1 string Unique id for inter-element referencing
..... extension 0..* Extension Additional content defined by implementations
..... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
..... description 0..1 markdown A text description or summary of the variable
..... note 0..* Annotation Footnotes and/or explanatory notes
..... variableRole Σ 1..1 code population | exposure | outcome | covariate
Binding: EvidenceVariableRole (required): The role that the variable plays.


Required Pattern: outcome
..... roleSubtype Σ 0..1 CodeableConcept subgroup | variable-A | variable-B | variable-AB | confounder | collider | mediator | effect-modifier
Binding: EvidenceVariableRoleSubtype (extensible): The sub-role that the variable plays.

..... comparatorCategory 0..1 string The reference value used for comparison
..... observed Σ 0..1 Reference(ParticipantFlowEvidenceVariable) Definition of the actual variable related to the statistic(s)
... synthesisType 0..1 CodeableConcept The method to combine studies
Binding: StatisticSynthesisType (extensible): Types of combining results from a body of evidence (e.g. summary data meta-analysis).

... studyDesign 0..* CodeableConcept The design of the study that produced this evidence
Binding: StudyDesign (extensible): This is a set of terms for study design characteristics.


... statistic 0..* BackboneElement Values and parameters for a single statistic
.... id 0..1 string Unique id for inter-element referencing
.... extension 0..* Extension Additional content defined by implementations
.... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
.... description 0..1 markdown Description of content
.... note 0..* Annotation Footnotes and/or explanatory notes
.... statisticType 0..1 CodeableConcept Type of statistic, e.g., relative risk
Binding: StatisticType (extensible)
.... category 0..1 CodeableConcept Associated category for categorical variable
.... quantity 0..1 Quantity Statistic value
.... numberOfEvents 0..1 unsignedInt The number of events associated with the statistic
.... sampleSize 0..1 BackboneElement Number of samples in the statistic
..... id 0..1 string Unique id for inter-element referencing
..... extension 0..* Extension Additional content defined by implementations
..... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
..... description 0..1 markdown Textual description of sample size for statistic
..... note 0..* Annotation Footnote or explanatory note about the sample size
..... numberOfStudies 0..1 unsignedInt Number of contributing studies
..... numberOfParticipants 0..1 unsignedInt Cumulative number of participants
..... knownDataCount 0..1 unsignedInt Number of participants with known results for measured variables
.... attributeEstimate 0..* BackboneElement An attribute of the Statistic
..... id 0..1 string Unique id for inter-element referencing
..... extension 0..* Extension Additional content defined by implementations
..... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
..... description 0..1 markdown Textual description of the attribute estimate
..... note 0..* Annotation Footnote or explanatory note about the estimate
..... type 0..1 CodeableConcept The type of attribute estimate, e.g., confidence interval or p value
Binding: AttributeEstimateType (extensible)
..... quantity 0..1 Quantity The singular quantity of the attribute estimate, for attribute estimates represented as single values; also used to report unit of measure
..... level 0..1 decimal Level of confidence interval, e.g., 0.95 for 95% confidence interval
..... range 0..1 Range Lower and upper bound values of the attribute estimate
..... attributeEstimate 0..* See attributeEstimate (Evidence) A nested attribute estimate; which is the attribute estimate of an attribute estimate
... certainty 0..* BackboneElement Certainty or quality of the evidence
.... id 0..1 string Unique id for inter-element referencing
.... extension 0..* Extension Additional content defined by implementations
.... modifierExtension ?!Σ 0..* Extension Extensions that cannot be ignored even if unrecognized
.... description 0..1 markdown Textual description of certainty
.... note 0..* Annotation Footnotes and/or explanatory notes
.... type 0..1 CodeableConcept Aspect of certainty being rated
Binding: EvidenceCertaintyType (extensible): The aspect of quality, confidence, or certainty.

.... rating 0..1 CodeableConcept Assessment or judgement of the aspect
Binding: EvidenceCertaintyRating (extensible): The assessment of quality, confidence, or certainty.

.... rater 0..1 string Individual or group who did the rating
.... subcomponent 0..* See certainty (Evidence) A domain or subdomain of certainty

doco Documentation for this format

Terminology Bindings

PathConformanceValueSet / CodeURI
Evidence.languagerequiredAllLanguages
http://hl7.org/fhir/ValueSet/all-languages|6.0.0-ballot2
from the FHIR Standard
Evidence.versionAlgorithm[x]extensibleVersionAlgorithm
http://hl7.org/fhir/ValueSet/version-algorithm
from the FHIR Standard
Evidence.statusrequiredPublicationStatus
http://hl7.org/fhir/ValueSet/publication-status|6.0.0-ballot2
from the FHIR Standard
Evidence.variableDefinition.variableRolerequiredEvidenceVariableRole
http://hl7.org/fhir/ValueSet/variable-role|6.0.0-ballot2
from the FHIR Standard
Evidence.variableDefinition.roleSubtypeextensibleEvidenceVariableRoleSubtype
http://hl7.org/fhir/ValueSet/variable-role-subtype
from the FHIR Standard
Evidence.variableDefinition:population.variableRolerequiredPattern: population
http://hl7.org/fhir/ValueSet/variable-role|6.0.0-ballot2
from the FHIR Standard
Evidence.variableDefinition:population.roleSubtypeextensibleEvidenceVariableRoleSubtype
http://hl7.org/fhir/ValueSet/variable-role-subtype
from the FHIR Standard
Evidence.variableDefinition:outcome.variableRolerequiredPattern: outcome
http://hl7.org/fhir/ValueSet/variable-role|6.0.0-ballot2
from the FHIR Standard
Evidence.variableDefinition:outcome.roleSubtypeextensibleEvidenceVariableRoleSubtype
http://hl7.org/fhir/ValueSet/variable-role-subtype
from the FHIR Standard
Evidence.synthesisTypeextensibleStatisticSynthesisType
http://terminology.hl7.org/ValueSet/synthesis-type
Evidence.studyDesignextensibleStudyDesign
http://hl7.org/fhir/ValueSet/study-design
from the FHIR Standard
Evidence.statistic.statisticTypeextensibleStatisticType
http://hl7.org/fhir/ValueSet/statistic-type
from the FHIR Standard
Evidence.statistic.attributeEstimate.typeextensibleAttributeEstimateType
http://hl7.org/fhir/ValueSet/attribute-estimate-type
from the FHIR Standard
Evidence.statistic.modelCharacteristic.codeextensibleStatisticModelCode
http://hl7.org/fhir/ValueSet/statistic-model-code
from the FHIR Standard
Evidence.statistic.modelCharacteristic.variable.handlingrequiredEvidenceVariableHandling
http://hl7.org/fhir/ValueSet/variable-handling|6.0.0-ballot2
from the FHIR Standard
Evidence.certainty.typeextensibleEvidenceCertaintyType
http://hl7.org/fhir/ValueSet/certainty-type
from the FHIR Standard
Evidence.certainty.ratingextensibleEvidenceCertaintyRating
http://hl7.org/fhir/ValueSet/certainty-rating
from the FHIR Standard

Constraints

IdGradePath(s)DetailsRequirements
cnl-0warningEvidenceName should be usable as an identifier for the module by machine processing applications such as code generation
: name.exists() implies name.matches('^[A-Z]([A-Za-z0-9_]){1,254}$')
cnl-1warningEvidence.urlURL should not contain | or # - these characters make processing canonical references problematic
: exists() implies matches('^[^|# ]+$')
ele-1error**ALL** elementsAll FHIR elements must have a @value or children
: hasValue() or (children().count() > id.count())

This structure is derived from NonComparativeEvidence

Summary

Prohibited: 8 elements

Structures

This structure refers to these other structures:

Maturity: 1

 

Other representations of profile: CSV, Excel, Schematron