Evidence Based Medicine on FHIR Implementation Guide, published by HL7 International / Clinical Decision Support. This guide is not an authorized publication; it is the continuous build for version 2.0.0-ballot built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/ebm/ and changes regularly. See the Directory of published versions
: ConceptualCohortDefinition: Estimated glomerular filtration rate 45-59 - TTL Representation
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@prefix fhir: <http://hl7.org/fhir/> .
@prefix loinc: <https://loinc.org/rdf/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
# - resource -------------------------------------------------------------------
a fhir:Group ;
fhir:nodeRole fhir:treeRoot ;
fhir:id [ fhir:v "179897"] ; #
fhir:meta [
fhir:versionId [ fhir:v "7" ] ;
fhir:lastUpdated [ fhir:v "2024-11-16T19:29:59.618Z"^^xsd:dateTime ] ;
( fhir:profile [
fhir:v "http://hl7.org/fhir/uv/ebm/StructureDefinition/conceptual-cohort-definition"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/uv/ebm/StructureDefinition/conceptual-cohort-definition> ] [
fhir:v "http://hl7.org/fhir/uv/ebm/StructureDefinition/group-r6"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/uv/ebm/StructureDefinition/group-r6> ] )
] ; #
fhir:text [
fhir:status [ fhir:v "extensions" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: Group 179897</b></p><a name=\"179897\"> </a><a name=\"hc179897\"> </a><a name=\"179897-en-US\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">version: 7; Last updated: 2024-11-16 19:29:59+0000</p><p style=\"margin-bottom: 0px\">Profiles: <a href=\"StructureDefinition-conceptual-cohort-definition.html\">ConceptualCohortDefinition</a>, <a href=\"StructureDefinition-group-r6.html\">GroupR6</a></p></div><p><b>Artifact related artifact</b>: No display for RelatedArtifact (type: cite-as; citation: CohortDefinition: Estimated glomerular filtration rate 45-59 [Group]. Contributors: Brian S. Alper [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 179897. Revised 2023-12-03. Available at: https://fevir.net/resources/Group/179897. Computable resource at: https://fevir.net/resources/Group/179897.)</p><p><b>Artifact Author</b>: Brian S. Alper: </p><p><b>url</b>: <a href=\"https://fevir.net/resources/Group/179897\">https://fevir.net/resources/Group/179897</a></p><p><b>identifier</b>: FEvIR Object Identifier/https://fevir.net/FOI/179897</p><p><b>name</b>: EGFR_45_59</p><p><b>title</b>: ConceptualCohortDefinition: Estimated glomerular filtration rate 45-59</p><p><b>status</b>: Active</p><p><b>publisher</b>: Computable Publishing LLC</p><p><b>contact</b>: <a href=\"mailto:support@computablepublishing.com\">support@computablepublishing.com</a></p><p><b>description</b>: </p><div><p>A characteristic of estimated glomerular filtration rate (eGFR) of 45-59 mL/min/1.73m2 is shown here. LOINC Code guidance states 'If transitioning to the new 2021 calculations, note there are separate equations for male and female patients that need to be implemented. The same LOINC code is applied regardless of which sex-based equation is used to generate the result. Laboratories need to build each male and female equation within their LIS and validate per their accreditation requirements.' and 'While LOINC does not have a specific code for reporting the exact equation used to calculate eGFR, it may be appropriate for labs to transmit this information as part of the information contained in the result comment field. The individual laboratory should determine whether it is better to include the equation, or the author(s) of the equation, to identify the method used to perform the eGFR calculation.' This example uses Group.characteristic.determinedByExpression to show where the exact equation may be reported.</p>\n</div><p><b>copyright</b>: </p><div><p>https://creativecommons.org/licenses/by-nc-sa/4.0/</p>\n</div><p><b>membership</b>: Conceptual</p><h3>Characteristics</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td><td><b>Exclude</b></td><td><b>Description</b></td><td><b>DeterminedBy[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://loinc.org 98979-8}\">Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI 2021)</span></td><td>45-59</td><td>false</td><td><div><p>eGFR 45-59 mL/min/1.73m2 with CKD-EPI 2021 formula for a female</p>\n</div></td><td><a href=\"https://reference.medscape.com/calculator/251/egfr-using-ckd-epi-2021-update\"><code>GFR = 141 * min(Scr/κ,1)^α * max(Scr/κ, 1)^-1.209 * 0.993^Age * 1.018</code>("formula for female adults (in pseudo-code expression)")</a></td></tr></table></div>"
] ; #
fhir:extension ( [
fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/artifact-relatedArtifact"^^xsd:anyURI ] ;
fhir:value [
a fhir:RelatedArtifact ;
fhir:type [ fhir:v "cite-as" ] ;
fhir:citation [ fhir:v "CohortDefinition: Estimated glomerular filtration rate 45-59 [Group]. Contributors: Brian S. Alper [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 179897. Revised 2023-12-03. Available at: https://fevir.net/resources/Group/179897. Computable resource at: https://fevir.net/resources/Group/179897." ] ]
] [
fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/artifact-author"^^xsd:anyURI ] ;
fhir:value [
a fhir:ContactDetail ;
fhir:name [ fhir:v "Brian S. Alper" ] ]
] ) ; #
fhir:url [ fhir:v "https://fevir.net/resources/Group/179897"^^xsd:anyURI] ; #
fhir:identifier ( [
fhir:type [
( fhir:coding [
fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/v2-0203"^^xsd:anyURI ] ;
fhir:code [ fhir:v "ACSN" ] ;
fhir:display [ fhir:v "Accession ID" ] ] ) ;
fhir:text [ fhir:v "FEvIR Object Identifier" ] ] ;
fhir:system [ fhir:v "urn:ietf:rfc:3986"^^xsd:anyURI ] ;
fhir:value [ fhir:v "https://fevir.net/FOI/179897" ] ;
fhir:assigner [
fhir:display [ fhir:v "Computable Publishing LLC" ] ]
] ) ; #
fhir:name [ fhir:v "EGFR_45_59"] ; #
fhir:title [ fhir:v "ConceptualCohortDefinition: Estimated glomerular filtration rate 45-59"] ; #
fhir:status [ fhir:v "active"] ; #
fhir:publisher [ fhir:v "Computable Publishing LLC"] ; #
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fhir:value [ fhir:v "support@computablepublishing.com" ] ] )
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fhir:description [ fhir:v "A characteristic of estimated glomerular filtration rate (eGFR) of 45-59 mL/min/1.73m2 is shown here. LOINC Code guidance states 'If transitioning to the new 2021 calculations, note there are separate equations for male and female patients that need to be implemented. The same LOINC code is applied regardless of which sex-based equation is used to generate the result. Laboratories need to build each male and female equation within their LIS and validate per their accreditation requirements.' and 'While LOINC does not have a specific code for reporting the exact equation used to calculate eGFR, it may be appropriate for labs to transmit this information as part of the information contained in the result comment field. The individual laboratory should determine whether it is better to include the equation, or the author(s) of the equation, to identify the method used to perform the eGFR calculation.' This example uses Group.characteristic.determinedByExpression to show where the exact equation may be reported."] ; #
fhir:copyright [ fhir:v "https://creativecommons.org/licenses/by-nc-sa/4.0/"] ; #
fhir:membership [ fhir:v "conceptual"] ; #
fhir:characteristic ( [
fhir:code [
( fhir:coding [
a loinc:98979-8 ;
fhir:system [ fhir:v "http://loinc.org"^^xsd:anyURI ] ;
fhir:code [ fhir:v "98979-8" ] ;
fhir:display [ fhir:v "Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI 2021)" ] ] ) ] ;
fhir:value [
a fhir:Range ;
fhir:low [
fhir:value [ fhir:v "45"^^xsd:decimal ] ] ;
fhir:high [
fhir:value [ fhir:v "59"^^xsd:decimal ] ;
fhir:unit [ fhir:v "milliliter per minute per 1.73 square meter" ] ;
fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
fhir:code [ fhir:v "mL/min/1.73.m2" ] ] ] ;
fhir:exclude [ fhir:v "false"^^xsd:boolean ] ;
fhir:description [ fhir:v "eGFR 45-59 mL/min/1.73m2 with CKD-EPI 2021 formula for a female" ] ;
fhir:determinedBy [
a fhir:Expression ;
fhir:description [ fhir:v "formula for female adults (in pseudo-code expression)" ] ;
fhir:expression [ fhir:v "GFR = 141 * min(Scr/κ,1)^α * max(Scr/κ, 1)^-1.209 * 0.993^Age * 1.018" ] ;
fhir:reference [ fhir:v "https://reference.medscape.com/calculator/251/egfr-using-ckd-epi-2021-update"^^xsd:anyURI ] ]
] ) . #
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