Evidence Based Medicine on FHIR Implementation Guide
1.0.0-ballot2 - STU 1 ballot International flag

Evidence Based Medicine on FHIR Implementation Guide, published by HL7 International / Clinical Decision Support. This guide is not an authorized publication; it is the continuous build for version 1.0.0-ballot2 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/ebm/ and changes regularly. See the Directory of published versions

Example EvidenceVariable: Health-related Quality of Life (NCT03640312)

version: 25; Last updated: 2025-08-15 10:32:26+0000

Profile: VariableDefinition

EvidenceVariableHandlingDetail: Evidence variable handling not specified

url: https://fevir.net/resources/EvidenceVariable/367890

identifier: FEvIR Object Identifier/367890, FEvIR Linking Identifier/NCT03640312-secondaryOutcome-7

name: Health_related_Quality_of_Life_NCT03640312

title: Health-related Quality of Life (NCT03640312)

citeAs:

Health-related Quality of Life (NCT03640312) [Database Entry: FHIR EvidenceVariable Resource]. Contributors: Computable Publishing®: ClinicalTrials.gov-to-FEvIR Converter [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 367890. Revised 2025-08-15. Available at: https://fevir.net/resources/EvidenceVariable/367890. Computable resource at: https://fevir.net/resources/EvidenceVariable/367890#json.

status: Active

author: Computable Publishing®: ClinicalTrials.gov-to-FEvIR Converter:

publisher: Computable Publishing LLC

contact: support@computablepublishing.com

description:

Mean change (from baseline) in health-related quality of life using Patient-Reported Outcomes Measurement Information System (PROMIS) Global Health instrument. PROMIS Global Health is a gauge of general health-care related quality of life. Possible PROMIS Global Physical Health and Global Mental Health scores range from 0-20, with 20 indicating best possible state of health. Raw scores are converted to T-scores to compare to a standardized population. A PROMIS T-score of 50 represents the mean of the population (SD = 10). Higher values here also indicate better health. A positive change in T score, as reported in this outcome measure, would represent an improvement in Global Physical Health or Global Mental Health at 12 weeks compared to baseline.

copyright:

https://creativecommons.org/licenses/by-nc-sa/4.0/

Definitions

-Reference
*Group: membership = conceptual

handling: extension

Generated Narrative: Group #variable-definition

membership: Conceptual

characteristic

code: defined by CodeableConcept

value: Health-related Quality of Life

exclude: false

Timings

-Text
*12 weeks