Evidence Based Medicine on FHIR Implementation Guide
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Evidence Based Medicine on FHIR Implementation Guide, published by HL7 International / Clinical Decision Support. This guide is not an authorized publication; it is the continuous build for version 1.0.0-ballot2 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/ebm/ and changes regularly. See the Directory of published versions

: Evidence for Results for Add-on Amlodipine at 6 weeks in GroupAssignment: Quadpill vs. Candesartan - TTL Representation

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@prefix fhir: <http://hl7.org/fhir/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

# - resource -------------------------------------------------------------------

 a fhir:Evidence ;
  fhir:nodeRole fhir:treeRoot ;
  fhir:id [ fhir:v "379741"] ; # 
  fhir:meta [
fhir:versionId [ fhir:v "3" ] ;
fhir:lastUpdated [ fhir:v "2025-07-01T16:47:40.277Z"^^xsd:dateTime ]
  ] ; # 
  fhir:text [
fhir:status [ fhir:v "extensions" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: Evidence 379741</b></p><a name=\"379741\"> </a><a name=\"hc379741\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">version: 3; Last updated: 2025-07-01 16:47:40+0000</p></div><p><b>ArtifactPublicationStatus</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/cited-artifact-status-type active}\">Active</span></p><p><b>url</b>: <a href=\"https://fevir.net/resources/Evidence/379741\">https://fevir.net/resources/Evidence/379741</a></p><p><b>identifier</b>: FEvIR Object Identifier/379741</p><p><b>name</b>: Evidence_for_Results_for_Add_on_Amlodipine_at_6_weeks_in_GroupAssignment_Quadpill_vs_Candesartan</p><p><b>title</b>: Evidence for Results for Add-on Amlodipine at 6 weeks in GroupAssignment: Quadpill vs. Candesartan</p><p><b>citeAs</b>: </p><div><p>Evidence for Results for Add-on Amlodipine at 6 weeks in GroupAssignment: Quadpill vs. Candesartan [Database Entry: FHIR Evidence Resource]. Contributors: Joanne Dehnbostel [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 379741. Revised 2025-07-01. Available at: https://fevir.net/resources/Evidence/379741. Computable resource at: https://fevir.net/resources/Evidence/379741#json.</p>\n</div><p><b>status</b>: Active</p><p><b>author</b>: Joanne Dehnbostel: </p><p><b>publisher</b>: Computable Publishing LLC</p><p><b>contact</b>: <a href=\"mailto:support@computablepublishing.com\">support@computablepublishing.com</a></p><p><b>copyright</b>: </p><div><p>https://creativecommons.org/licenses/by-nc-sa/4.0/</p>\n</div><h3>RelatesTos</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Target[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Part Of</td><td><a href=\"Composition-375280.html\">Outcome Measure Report for QUARTET USA Trial</a></td></tr></table><p><b>description</b>: </p><div><p>This Evidence Resource is referenced in an example for the EBMonFHIR Implementation Guide.</p>\n</div><blockquote><p><b>variableDefinition</b></p><p><b>variableRole</b>: Population</p><p><b>observed</b>: <a href=\"EvidenceVariable-375183.html\">GroupAssignment: Quadpill vs. Candesartan</a></p></blockquote><blockquote><p><b>variableDefinition</b></p><p><b>variableRole</b>: Outcome</p><p><b>observed</b>: <a href=\"EvidenceVariable-375203.html\">Add-on Amlodipine at 6 weeks</a></p></blockquote><blockquote><p><b>statistic</b></p><p><b>statisticType</b>: <span title=\"Codes:{https://fevir.net/sevco STATO:0000182}\">odds ratio</span></p><p><b>quantity</b>: 0.08</p><p><b>numberAffected</b>: 22</p><h3>SampleSizes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td><td><b>NumberOfParticipants</b></td><td><b>KnownDataCount</b></td></tr><tr><td style=\"display: none\">*</td><td/><td>62</td><td>60</td></tr></table><blockquote><p><b>attributeEstimate</b></p><p><b>type</b>: <span title=\"Codes:{https://fevir.net/sevco STATO:0000196}\">confidence interval</span></p><p><b>level</b>: 0.95</p><p><b>range</b>: 0.02-0.41</p></blockquote><blockquote><p><b>attributeEstimate</b></p><p><b>type</b>: <span title=\"Codes:{https://fevir.net/sevco STATO:0000700}\">p-value</span></p><p><b>quantity</b>: 0.003</p></blockquote></blockquote></div>"^^rdf:XMLLiteral
  ] ; # 
  fhir:extension ( [
fhir:url [ fhir:v "http://hl7.org/fhir/uv/ebm/StructureDefinition/artifact-publication-status"^^xsd:anyURI ] ;
fhir:value [
a fhir:CodeableConcept ;
      ( fhir:coding [
fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/cited-artifact-status-type"^^xsd:anyURI ] ;
fhir:code [ fhir:v "active" ] ;
fhir:display [ fhir:v "Active" ]       ] )     ]
  ] ) ; # 
  fhir:url [ fhir:v "https://fevir.net/resources/Evidence/379741"^^xsd:anyURI] ; # 
  fhir:identifier ( [
fhir:type [
      ( fhir:coding [
fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/v2-0203"^^xsd:anyURI ] ;
fhir:code [ fhir:v "ACSN" ] ;
fhir:display [ fhir:v "Accession ID" ]       ] ) ;
fhir:text [ fhir:v "FEvIR Object Identifier" ]     ] ;
fhir:system [ fhir:v "https://fevir.net/FOI"^^xsd:anyURI ] ;
fhir:value [ fhir:v "379741" ] ;
fhir:assigner [
fhir:display [ fhir:v "Computable Publishing LLC" ]     ]
  ] ) ; # 
  fhir:name [ fhir:v "Evidence_for_Results_for_Add_on_Amlodipine_at_6_weeks_in_GroupAssignment_Quadpill_vs_Candesartan"] ; # 
  fhir:title [ fhir:v "Evidence for Results for Add-on Amlodipine at 6 weeks in GroupAssignment: Quadpill vs. Candesartan"] ; # 
  fhir:citeAs [ fhir:v "Evidence for Results for Add-on Amlodipine at 6 weeks in GroupAssignment: Quadpill vs. Candesartan [Database Entry: FHIR Evidence Resource]. Contributors: Joanne Dehnbostel [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 379741. Revised 2025-07-01. Available at: https://fevir.net/resources/Evidence/379741. Computable resource at: https://fevir.net/resources/Evidence/379741#json."] ; # 
  fhir:status [ fhir:v "active"] ; # 
  fhir:author ( [
fhir:name [ fhir:v "Joanne Dehnbostel" ]
  ] ) ; # 
  fhir:publisher [ fhir:v "Computable Publishing LLC"] ; # 
  fhir:contact ( [
    ( fhir:telecom [
fhir:system [ fhir:v "email" ] ;
fhir:value [ fhir:v "support@computablepublishing.com" ]     ] )
  ] ) ; # 
  fhir:copyright [ fhir:v "https://creativecommons.org/licenses/by-nc-sa/4.0/"] ; # 
  fhir:relatesTo ( [
fhir:type [ fhir:v "part-of" ] ;
fhir:target [
a fhir:Reference ;
fhir:reference [ fhir:v "Composition/375280" ] ;
fhir:type [ fhir:v "Composition"^^xsd:anyURI ] ;
fhir:display [ fhir:v "Outcome Measure Report for QUARTET USA Trial" ]     ]
  ] ) ; # 
  fhir:description [ fhir:v "This Evidence Resource is referenced in an example for the EBMonFHIR Implementation Guide."] ; # 
  fhir:variableDefinition ( [
fhir:variableRole [ fhir:v "population" ] ;
fhir:observed [
fhir:reference [ fhir:v "EvidenceVariable/375183" ] ;
fhir:type [ fhir:v "EvidenceVariable"^^xsd:anyURI ] ;
fhir:display [ fhir:v "GroupAssignment: Quadpill vs. Candesartan" ]     ]
  ] [
fhir:variableRole [ fhir:v "outcome" ] ;
fhir:observed [
fhir:reference [ fhir:v "EvidenceVariable/375203" ] ;
fhir:type [ fhir:v "EvidenceVariable"^^xsd:anyURI ] ;
fhir:display [ fhir:v "Add-on Amlodipine at 6 weeks" ]     ]
  ] ) ; # 
  fhir:statistic ( [
fhir:statisticType [
      ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/sevco"^^xsd:anyURI ] ;
fhir:code [ fhir:v "STATO:0000182" ] ;
fhir:display [ fhir:v "odds ratio" ]       ] )     ] ;
fhir:quantity [
fhir:value [ fhir:v 0.08 ]     ] ;
fhir:numberAffected [ fhir:v "22"^^xsd:nonNegativeInteger ] ;
fhir:sampleSize [
      ( fhir:extension [
fhir:url [ fhir:v "http://hl7.org/fhir/uv/ebm/StructureDefinition/number-analyzed"^^xsd:anyURI ] ;
fhir:value [
a fhir:unsignedInt ;
fhir:v "60"^^xsd:nonNegativeInteger         ]       ] ) ;
fhir:numberOfParticipants [ fhir:v "62"^^xsd:nonNegativeInteger ] ;
fhir:knownDataCount [ fhir:v "60"^^xsd:nonNegativeInteger ]     ] ;
    ( fhir:attributeEstimate [
fhir:type [
        ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/sevco"^^xsd:anyURI ] ;
fhir:code [ fhir:v "STATO:0000196" ] ;
fhir:display [ fhir:v "confidence interval" ]         ] )       ] ;
fhir:level [ fhir:v 0.95 ] ;
fhir:range [
fhir:low [
fhir:value [ fhir:v 0.02 ]         ] ;
fhir:high [
fhir:value [ fhir:v 0.41 ]         ]       ]     ] [
fhir:type [
        ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/sevco"^^xsd:anyURI ] ;
fhir:code [ fhir:v "STATO:0000700" ] ;
fhir:display [ fhir:v "p-value" ]         ] )       ] ;
fhir:quantity [
fhir:value [ fhir:v 0.003 ]       ]     ] )
  ] ) . #