Evidence Based Medicine on FHIR Implementation Guide
1.0.0-ballot2 - STU 1 ballot International flag

Evidence Based Medicine on FHIR Implementation Guide, published by HL7 International / Clinical Decision Support. This guide is not an authorized publication; it is the continuous build for version 1.0.0-ballot2 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/ebm/ and changes regularly. See the Directory of published versions

Example Evidence: MAGIC-derived Evidence: Health-related quality of life with GLP-1 RA vs. Standard care in Adults with type 2 diabetes with moderate CV risk

Generated Narrative: Evidence 236564

version: 65; Last updated: 2025-03-20 18:40:09+0000

Profile: ComparativeEvidence

RelatesTo

  • type: part-of
  • targetReference: MAGICapp Conversion Report: SGLT2 inhibitors and GLP-1 RA for type 2 diabetes (Identifier: FEvIR Linking Identifier/MAGIC-5288-j1Wqrn-conversion-report)

url: https://fevir.net/resources/Evidence/236564

identifier: FEvIR Object Identifier/https://fevir.net/FOI/236564, outcomeId/109569, picoId/85789, sectionId/73212

name: Health_related_quality_of_life_from_MAGICapp_109569

title: MAGIC-derived Evidence: Health-related quality of life with GLP-1 RA vs. Standard care in Adults with type 2 diabetes with moderate CV risk

status: Active

publisher: Computable Publishing LLC

contact: support@computablepublishing.com

author: Computable Publishing®: MAGIC-to-FEvIR Converter:

UseContexts

-CodeValue[x]
*Evidence Based Medicine on FHIR Implementation Guide Code System evidence-communication: Evidence CommunicationComparativeEvidence

copyright:

https://creativecommons.org/licenses/by-nc-sa/4.0/

description:

This Evidence Resource is referenced in an example for the EBMonFHIR Implementation Guide.

assertion:

GLP-1 receptor agonists may have little or no impact on health-related quality of life.

variableDefinition

description:

Adults with type 2 diabetes with moderate CV risk

variableRole: Population

observed: Adults with type 2 diabetes and established CVD (but no CKD)

variableDefinition

description:

GroupAssignment: GLP-1 RA vs. Standard care

variableRole: Exposure

comparatorCategory: Standard care

observed: GroupAssignment: GLP-1 RA vs. Standard care

variableDefinition

description:

Health-related quality of life

variableRole: Outcome

observed: Health-related quality of life

synthesisType: SYSTEMATIC_REVIEW

studyDesign: NOTSET

statistic

description:

SMD 0.13 (CI95 0.03 to 0.23 )

statisticType: Standardized Mean Difference

quantity: 0.13

AttributeEstimates

-TypeRange
*CI950.03-0.23

certainty

description:

Due to very serious imprecision

type: Overall certainty

rating: Low certainty

Subcomponents

-TypeRating
*Risk of BiasNOTSET
*InconsistencyNOTSET
*IndirectnessNOTSET
*ImprecisionVERY_SERIOUS
*Publication BiasNOTSET