Evidence Based Medicine on FHIR Implementation Guide
1.0.0-ballot2 - STU 1 ballot
Evidence Based Medicine on FHIR Implementation Guide
1.0.0-ballot2 - STU 1 ballot
Evidence Based Medicine on FHIR Implementation Guide, published by HL7 International / Clinical Decision Support. This guide is not an authorized publication; it is the continuous build for version 1.0.0-ballot2 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/ebm/ and changes regularly. See the Directory of published versions
Generated Narrative: Evidence 236549
version: 65; Last updated: 2025-03-20 18:40:09+0000
Profile: ComparativeEvidence
RelatesTo
- type: part-of
- targetReference: MAGICapp Conversion Report: SGLT2 inhibitors and GLP-1 RA for type 2 diabetes (Identifier: FEvIR Linking Identifier/MAGIC-5288-j1Wqrn-conversion-report)
url: https://fevir.net/resources/Evidence/236549
identifier: FEvIR Object Identifier/https://fevir.net/FOI/236549, outcomeId/313879, picoId/85789, sectionId/73212
name: Nonfatal_stroke_from_MAGICapp_313879
title: MAGIC-derived Evidence: Nonfatal stroke with GLP-1 RA vs. Standard care in Adults with type 2 diabetes with moderate CV risk
status: Active
publisher: Computable Publishing LLC
contact: support@computablepublishing.com
author: Computable Publishing®: MAGIC-to-FEvIR Converter:
| Code | Value[x] |
| Evidence Based Medicine on FHIR Implementation Guide Code System evidence-communication: Evidence Communication | ComparativeEvidence |
copyright:
https://creativecommons.org/licenses/by-nc-sa/4.0/
description:
This Evidence Resource is referenced in an example for the EBMonFHIR Implementation Guide.
assertion:
GLP-1 receptor agonists probably reduce the risk of nonfatal stroke compared with standard care.
variableDefinition
description:
Adults with type 2 diabetes with moderate CV risk
variableRole: Population
observed: Adults with type 2 diabetes and established CVD (but no CKD)
variableDefinition
description:
GroupAssignment: GLP-1 RA vs. Standard care
variableRole: Exposure
comparatorCategory: Standard care
variableDefinition
description:
Nonfatal stroke
variableRole: Outcome
observed: Nonfatal stroke
synthesisType: SYSTEMATIC_REVIEW
studyDesign: randomized assignment
statistic
description:
Risk Difference -1.6% (CI95 -2.4% to -0.7%)
statisticType: Risk Difference
quantity: -0.016
SampleSizes
NumberOfStudies NumberOfParticipants 29 66900 AttributeEstimates
Type Range CI95 -0.024--0.007
statistic
description:
OR 0.84 (CI95 0.76 to 0.93)
statisticType: Odds Ratio
quantity: 0.84
SampleSizes
NumberOfStudies NumberOfParticipants 29 66900 AttributeEstimates
Type Range CI95 0.76-0.93
certainty
description:
Due to serious imprecision
type: Overall certainty
rating: Moderate certainty
Subcomponents
Type Rating Risk of Bias NOTSET Inconsistency NOTSET Indirectness NOTSET Imprecision NOTSET Publication Bias NOTSET
IG © 2024+ HL7 International / Clinical Decision Support. Package hl7.fhir.uv.ebm#1.0.0-ballot2 based on FHIR 6.0.0-ballot2. Generated 2025-03-27
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