Evidence Based Medicine on FHIR Implementation Guide
2.0.0-ballot - ballot
Evidence Based Medicine on FHIR Implementation Guide
2.0.0-ballot - ballot
Evidence Based Medicine on FHIR Implementation Guide, published by HL7 International / Clinical Decision Support. This guide is not an authorized publication; it is the continuous build for version 2.0.0-ballot built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/ebm/ and changes regularly. See the Directory of published versions
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<display value="OutcomeDefinition: All-cause mortality"/>
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<div xmlns="http://www.w3.org/1999/xhtml">2 studies, 1282 participants</div>
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<reference value="Evidence/236955"/>
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<display
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<display
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<title value="Effect Estimate"/>
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<reference value="Evidence/236954"/>
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<display
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<div xmlns="http://www.w3.org/1999/xhtml">Moderate certainty</div>
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<div xmlns="http://www.w3.org/1999/xhtml">SGLT2 inhibitors probably reduce the risk of all cause mortality compared with GLP-1 receptor agonists.</div>
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<div xmlns="http://www.w3.org/1999/xhtml"><p>[No data.]</p></div>
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<div xmlns="http://www.w3.org/1999/xhtml">Cardiovascular mortality</div>
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<display value="OutcomeDefinition: Cardiovascular mortality"/>
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<div xmlns="http://www.w3.org/1999/xhtml">1 studies, 463 participants</div>
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<entry>🔗
<reference value="Evidence/236957"/>
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<display
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<title value="Result Without Treatment"/>
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<div xmlns="http://www.w3.org/1999/xhtml">15.7%</div>
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<entry>🔗
<reference value="Evidence/236958"/>
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<text value="FEvIR Linking Identifier"/>
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<display
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<title value="Result With Treatment--Observed"/>
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<div xmlns ="http://www.w3.org/1999/xhtml">[No data]</div>
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<div xmlns="http://www.w3.org/1999/xhtml">15.2%</div>
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<entry>🔗
<reference value="Evidence/236958"/>
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<text value="FEvIR Linking Identifier"/>
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<display
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<entry>🔗
<reference value="Evidence/236957"/>
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<display
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<section>
<title value="Effect Estimate"/>
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<text>
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<div xmlns="http://www.w3.org/1999/xhtml">Risk Difference -0.5% ( -2.2% to 1.2%); Odds Ratio 0.96 ( 0.84 to 1.09)</div>
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<entry>🔗
<reference value="Evidence/236957"/>
<type value="Evidence"/>
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<type>
<text value="FEvIR Linking Identifier"/>
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<display
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<title value="Certainty of Evidence"/>
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<text>
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<div xmlns="http://www.w3.org/1999/xhtml">Moderate certainty</div>
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<entry>🔗
<reference value="Evidence/236957"/>
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<div xmlns="http://www.w3.org/1999/xhtml">There probably be no important difference between SGLT2 inhibitors and GLP-1 receptor agonists.</div>
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<entry>🔗
<reference value="Evidence/236957"/>
<type value="Evidence"/>
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<type>
<text value="FEvIR Linking Identifier"/>
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<display
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<section>
<title value="Nonfatal myocardial infarction"/>
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<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="summary-of-findings-entry-for-a-single-outcome"/>
<display value="Summary of findings entry for a single outcome"/>
</coding>
</code>
<focus>🔗
<reference value="EvidenceVariable/236959"/>
<type value="EvidenceVariable"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value value="MAGIC-5288-j1Wqrn-313958"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display value="OutcomeDefinition: Nonfatal myocardial infarction"/>
</focus>
<text>
<status value="empty"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p>[No data.]</p></div>
</text>
<section>
<title value="Outcome"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="outcome-measure"/>
<display value="Outcome Measure"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">Nonfatal myocardial infarction</div>
</text>
<entry>🔗
<reference value="EvidenceVariable/236959"/>
<type value="EvidenceVariable"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value value="MAGIC-5288-j1Wqrn-313958"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display value="OutcomeDefinition: Nonfatal myocardial infarction"/>
</entry>
</section>
<section>
<title value="Sample Size"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="sample-size"/>
<display value="Sample Size"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">1 studies, 463 participants</div>
</text>
<entry>🔗
<reference value="Evidence/236960"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313958-comparative-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Nonfatal myocardial infarction with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes"/>
</entry>
</section>
<section>
<title value="Result Without Treatment"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-comparator-alone"/>
<display value="Result with comparator alone"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">17.7%</div>
</text>
<entry>🔗
<reference value="Evidence/236961"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313958-comparator-only-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Nonfatal myocardial infarction Comparator Evidence"/>
</entry>
</section>
<section>
<title value="Result With Treatment--Observed"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-intervention-alone"/>
<display value="Result with intervention alone"/>
</coding>
</code>
<text>
<status value="empty"/>
<div xmlns ="http://www.w3.org/1999/xhtml">[No data]</div>
</text>
</section>
<section>
<title value="Result With Treatment--Derived"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-intervention-alone-calculated"/>
<display value="Result with intervention alone (calculated)"/>
</coding>
<text
value="result with intervention with calculated value derived from the control group and effect estimate"/>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">17%</div>
</text>
<entry>🔗
<reference value="Evidence/236961"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313958-comparator-only-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Nonfatal myocardial infarction Comparator Evidence"/>
</entry>
<entry>🔗
<reference value="Evidence/236960"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313958-comparative-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Nonfatal myocardial infarction with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes"/>
</entry>
</section>
<section>
<title value="Effect Estimate"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-intervention-vs-comparator"/>
<display value="Result with intervention vs. comparator"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">Risk Difference -0.7% ( -2.4% to 1.1%); Odds Ratio 0.95 ( 0.84 to 1.08)</div>
</text>
<entry>🔗
<reference value="Evidence/236960"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313958-comparative-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Nonfatal myocardial infarction with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes"/>
</entry>
</section>
<section>
<title value="Certainty of Evidence"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="certainty-of-evidence"/>
<display value="Certainty of Evidence"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">Moderate certainty</div>
</text>
<entry>🔗
<reference value="Evidence/236960"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313958-comparative-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Nonfatal myocardial infarction with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes"/>
</entry>
</section>
<section>
<title value="Assertion"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="assertion"/>
<display value="Assertion"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">There is no important difference between SGLT2 inhibitors and GLP-1 receptor agonists on the risk of nonfatal myocardial infarction.</div>
</text>
<entry>🔗
<reference value="Evidence/236960"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313958-comparative-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Nonfatal myocardial infarction with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes"/>
</entry>
</section>
</section>
<section>
<title value="Nonfatal stroke"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="summary-of-findings-entry-for-a-single-outcome"/>
<display value="Summary of findings entry for a single outcome"/>
</coding>
</code>
<focus>🔗
<reference value="EvidenceVariable/236962"/>
<type value="EvidenceVariable"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value value="MAGIC-5288-j1Wqrn-313959"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display value="OutcomeDefinition: Nonfatal stroke"/>
</focus>
<text>
<status value="empty"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p>[No data.]</p></div>
</text>
<section>
<title value="Outcome"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="outcome-measure"/>
<display value="Outcome Measure"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">Nonfatal stroke</div>
</text>
<entry>🔗
<reference value="EvidenceVariable/236962"/>
<type value="EvidenceVariable"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value value="MAGIC-5288-j1Wqrn-313959"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display value="OutcomeDefinition: Nonfatal stroke"/>
</entry>
</section>
<section>
<title value="Sample Size"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="sample-size"/>
<display value="Sample Size"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">2 studies, 1282 participants</div>
</text>
<entry>🔗
<reference value="Evidence/236963"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313959-comparative-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Nonfatal stroke with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes"/>
</entry>
</section>
<section>
<title value="Result Without Treatment"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-comparator-alone"/>
<display value="Result with comparator alone"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">16.5%</div>
</text>
<entry>🔗
<reference value="Evidence/236964"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313959-comparator-only-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Nonfatal stroke Comparator Evidence"/>
</entry>
</section>
<section>
<title value="Result With Treatment--Observed"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-intervention-alone"/>
<display value="Result with intervention alone"/>
</coding>
</code>
<text>
<status value="empty"/>
<div xmlns ="http://www.w3.org/1999/xhtml">[No data]</div>
</text>
</section>
<section>
<title value="Result With Treatment--Derived"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-intervention-alone-calculated"/>
<display value="Result with intervention alone (calculated)"/>
</coding>
<text
value="result with intervention with calculated value derived from the control group and effect estimate"/>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">19.2%</div>
</text>
<entry>🔗
<reference value="Evidence/236964"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313959-comparator-only-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Nonfatal stroke Comparator Evidence"/>
</entry>
<entry>🔗
<reference value="Evidence/236963"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313959-comparative-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Nonfatal stroke with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes"/>
</entry>
</section>
<section>
<title value="Effect Estimate"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-intervention-vs-comparator"/>
<display value="Result with intervention vs. comparator"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">Risk Difference 2.7% ( 0.4% to 5.3%); Odds Ratio 1.2 ( 1.03 to 1.41)</div>
</text>
<entry>🔗
<reference value="Evidence/236963"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313959-comparative-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Nonfatal stroke with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes"/>
</entry>
</section>
<section>
<title value="Certainty of Evidence"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="certainty-of-evidence"/>
<display value="Certainty of Evidence"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">Moderate certainty</div>
</text>
<entry>🔗
<reference value="Evidence/236963"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313959-comparative-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Nonfatal stroke with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes"/>
</entry>
</section>
<section>
<title value="Assertion"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="assertion"/>
<display value="Assertion"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"> SGLT2 inhibitors probably increase the risk of nonfatal stroke compared with GLP-1 receptor agonists.</div>
</text>
<entry>🔗
<reference value="Evidence/236963"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313959-comparative-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Nonfatal stroke with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes"/>
</entry>
</section>
</section>
<section>
<title value="End-stage kidney disease"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="summary-of-findings-entry-for-a-single-outcome"/>
<display value="Summary of findings entry for a single outcome"/>
</coding>
</code>
<focus>🔗
<reference value="EvidenceVariable/236965"/>
<type value="EvidenceVariable"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value value="MAGIC-5288-j1Wqrn-313960"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display value="OutcomeDefinition: End-stage kidney disease"/>
</focus>
<text>
<status value="empty"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p>[No data.]</p></div>
</text>
<section>
<title value="Outcome"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="outcome-measure"/>
<display value="Outcome Measure"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">End-stage kidney disease</div>
</text>
<entry>🔗
<reference value="EvidenceVariable/236965"/>
<type value="EvidenceVariable"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value value="MAGIC-5288-j1Wqrn-313960"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display value="OutcomeDefinition: End-stage kidney disease"/>
</entry>
</section>
<section>
<title value="Sample Size"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="sample-size"/>
<display value="Sample Size"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">1 studies, 463 participants</div>
</text>
<entry>🔗
<reference value="Evidence/236966"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313960-comparative-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: End-stage kidney disease with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes"/>
</entry>
</section>
<section>
<title value="Result Without Treatment"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-comparator-alone"/>
<display value="Result with comparator alone"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">11.9%</div>
</text>
<entry>🔗
<reference value="Evidence/236967"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313960-comparator-only-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: End-stage kidney disease Comparator Evidence"/>
</entry>
</section>
<section>
<title value="Result With Treatment--Observed"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-intervention-alone"/>
<display value="Result with intervention alone"/>
</coding>
</code>
<text>
<status value="empty"/>
<div xmlns ="http://www.w3.org/1999/xhtml">[No data]</div>
</text>
</section>
<section>
<title value="Result With Treatment--Derived"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-intervention-alone-calculated"/>
<display value="Result with intervention alone (calculated)"/>
</coding>
<text
value="result with intervention with calculated value derived from the control group and effect estimate"/>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">10.9%</div>
</text>
<entry>🔗
<reference value="Evidence/236967"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313960-comparator-only-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: End-stage kidney disease Comparator Evidence"/>
</entry>
<entry>🔗
<reference value="Evidence/236966"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313960-comparative-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: End-stage kidney disease with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes"/>
</entry>
</section>
<section>
<title value="Effect Estimate"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-intervention-vs-comparator"/>
<display value="Result with intervention vs. comparator"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">Risk Difference -1% ( -3.4% to 2%); Odds Ratio 0.91 ( 0.69 to 1.2)</div>
</text>
<entry>🔗
<reference value="Evidence/236966"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313960-comparative-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: End-stage kidney disease with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes"/>
</entry>
</section>
<section>
<title value="Certainty of Evidence"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="certainty-of-evidence"/>
<display value="Certainty of Evidence"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">Moderate certainty</div>
</text>
<entry>🔗
<reference value="Evidence/236966"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313960-comparative-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: End-stage kidney disease with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes"/>
</entry>
</section>
<section>
<title value="Assertion"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="assertion"/>
<display value="Assertion"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">There probably be no important difference between SGLT2 inhibitors and GLP-1 receptor agonists.</div>
</text>
<entry>🔗
<reference value="Evidence/236966"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313960-comparative-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: End-stage kidney disease with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes"/>
</entry>
</section>
</section>
<section>
<title value="Heart failure"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="summary-of-findings-entry-for-a-single-outcome"/>
<display value="Summary of findings entry for a single outcome"/>
</coding>
</code>
<focus>🔗
<reference value="EvidenceVariable/236968"/>
<type value="EvidenceVariable"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value value="MAGIC-5288-j1Wqrn-313961"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display value="OutcomeDefinition: Heart failure"/>
</focus>
<text>
<status value="empty"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p>[No data.]</p></div>
</text>
<section>
<title value="Outcome"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="outcome-measure"/>
<display value="Outcome Measure"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">Heart failure</div>
</text>
<entry>🔗
<reference value="EvidenceVariable/236968"/>
<type value="EvidenceVariable"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value value="MAGIC-5288-j1Wqrn-313961"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display value="OutcomeDefinition: Heart failure"/>
</entry>
</section>
<section>
<title value="Sample Size"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="sample-size"/>
<display value="Sample Size"/>
</coding>
</code>
<text>
<status value="empty"/>
<div xmlns="http://www.w3.org/1999/xhtml">[No sample size data found.]</div>
</text>
<entry>🔗
<reference value="Evidence/236969"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313961-comparative-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Heart failure with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes"/>
</entry>
</section>
<section>
<title value="Result Without Treatment"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-comparator-alone"/>
<display value="Result with comparator alone"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">22.4%</div>
</text>
<entry>🔗
<reference value="Evidence/236970"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313961-comparator-only-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Heart failure Comparator Evidence"/>
</entry>
</section>
<section>
<title value="Result With Treatment--Observed"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-intervention-alone"/>
<display value="Result with intervention alone"/>
</coding>
</code>
<text>
<status value="empty"/>
<div xmlns ="http://www.w3.org/1999/xhtml">[No data]</div>
</text>
</section>
<section>
<title value="Result With Treatment--Derived"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-intervention-alone-calculated"/>
<display value="Result with intervention alone (calculated)"/>
</coding>
<text
value="result with intervention with calculated value derived from the control group and effect estimate"/>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">17.6%</div>
</text>
<entry>🔗
<reference value="Evidence/236970"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313961-comparator-only-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Heart failure Comparator Evidence"/>
</entry>
<entry>🔗
<reference value="Evidence/236969"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313961-comparative-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Heart failure with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes"/>
</entry>
</section>
<section>
<title value="Effect Estimate"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-intervention-vs-comparator"/>
<display value="Result with intervention vs. comparator"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">Risk Difference -4.8% ( -6.6% to -2.7%); Odds Ratio 0.74 ( 0.65 to 0.85)</div>
</text>
<entry>🔗
<reference value="Evidence/236969"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313961-comparative-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Heart failure with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes"/>
</entry>
</section>
<section>
<title value="Certainty of Evidence"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="certainty-of-evidence"/>
<display value="Certainty of Evidence"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">High certainty</div>
</text>
<entry>🔗
<reference value="Evidence/236969"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313961-comparative-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Heart failure with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes"/>
</entry>
</section>
<section>
<title value="Assertion"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="assertion"/>
<display value="Assertion"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">SGLT2 inhibitors reduce the risk of heart failure compared with GLP-1 receptor agonists.</div>
</text>
<entry>🔗
<reference value="Evidence/236969"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313961-comparative-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Heart failure with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes"/>
</entry>
</section>
</section>
<section>
<title value="Diabetic ketoacidosis"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="summary-of-findings-entry-for-a-single-outcome"/>
<display value="Summary of findings entry for a single outcome"/>
</coding>
</code>
<focus>🔗
<reference value="EvidenceVariable/236971"/>
<type value="EvidenceVariable"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value value="MAGIC-5288-j1Wqrn-313962"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display value="OutcomeDefinition: Diabetic ketoacidosis"/>
</focus>
<text>
<status value="empty"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p>[No data.]</p></div>
</text>
<section>
<title value="Outcome"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="outcome-measure"/>
<display value="Outcome Measure"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">Diabetic ketoacidosis</div>
</text>
<entry>🔗
<reference value="EvidenceVariable/236971"/>
<type value="EvidenceVariable"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value value="MAGIC-5288-j1Wqrn-313962"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display value="OutcomeDefinition: Diabetic ketoacidosis"/>
</entry>
</section>
<section>
<title value="Sample Size"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="sample-size"/>
<display value="Sample Size"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">1 studies, 463 participants</div>
</text>
<entry>🔗
<reference value="Evidence/236972"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313962-comparative-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Diabetic ketoacidosis with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes"/>
</entry>
</section>
<section>
<title value="Result Without Treatment"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-comparator-alone"/>
<display value="Result with comparator alone"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">0.1%</div>
</text>
<entry>🔗
<reference value="Evidence/236973"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313962-comparator-only-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Diabetic ketoacidosis Comparator Evidence"/>
</entry>
</section>
<section>
<title value="Result With Treatment--Observed"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-intervention-alone"/>
<display value="Result with intervention alone"/>
</coding>
</code>
<text>
<status value="empty"/>
<div xmlns ="http://www.w3.org/1999/xhtml">[No data]</div>
</text>
</section>
<section>
<title value="Result With Treatment--Derived"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-intervention-alone-calculated"/>
<display value="Result with intervention alone (calculated)"/>
</coding>
<text
value="result with intervention with calculated value derived from the control group and effect estimate"/>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">0.2%</div>
</text>
<entry>🔗
<reference value="Evidence/236973"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313962-comparator-only-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Diabetic ketoacidosis Comparator Evidence"/>
</entry>
<entry>🔗
<reference value="Evidence/236972"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313962-comparative-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Diabetic ketoacidosis with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes"/>
</entry>
</section>
<section>
<title value="Effect Estimate"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-intervention-vs-comparator"/>
<display value="Result with intervention vs. comparator"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">Risk Difference 0.1% ( 0% to 0.3%); Odds Ratio 1.71 ( 0.79 to 3.69)</div>
</text>
<entry>🔗
<reference value="Evidence/236972"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313962-comparative-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Diabetic ketoacidosis with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes"/>
</entry>
</section>
<section>
<title value="Certainty of Evidence"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="certainty-of-evidence"/>
<display value="Certainty of Evidence"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">High certainty</div>
</text>
<entry>🔗
<reference value="Evidence/236972"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313962-comparative-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Diabetic ketoacidosis with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes"/>
</entry>
</section>
<section>
<title value="Assertion"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="assertion"/>
<display value="Assertion"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">There is no important difference between SGLT2 inhibitors and GLP-1 receptor agonists on the risk of diabetic ketoacidosis.</div>
</text>
<entry>🔗
<reference value="Evidence/236972"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313962-comparative-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Diabetic ketoacidosis with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes"/>
</entry>
</section>
</section>
<section>
<title value="Serious hyperglycaemia"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="summary-of-findings-entry-for-a-single-outcome"/>
<display value="Summary of findings entry for a single outcome"/>
</coding>
</code>
<focus>🔗
<reference value="EvidenceVariable/236974"/>
<type value="EvidenceVariable"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value value="MAGIC-5288-j1Wqrn-313963"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display value="OutcomeDefinition: Serious hyperglycaemia"/>
</focus>
<text>
<status value="empty"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p>[No data.]</p></div>
</text>
<section>
<title value="Outcome"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="outcome-measure"/>
<display value="Outcome Measure"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">Serious hyperglycaemia</div>
</text>
<entry>🔗
<reference value="EvidenceVariable/236974"/>
<type value="EvidenceVariable"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value value="MAGIC-5288-j1Wqrn-313963"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display value="OutcomeDefinition: Serious hyperglycaemia"/>
</entry>
</section>
<section>
<title value="Sample Size"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="sample-size"/>
<display value="Sample Size"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">1 studies, 463 participants</div>
</text>
<entry>🔗
<reference value="Evidence/236975"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313963-comparative-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Serious hyperglycaemia with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes"/>
</entry>
</section>
<section>
<title value="Result Without Treatment"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-comparator-alone"/>
<display value="Result with comparator alone"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">1%</div>
</text>
<entry>🔗
<reference value="Evidence/236976"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313963-comparator-only-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Serious hyperglycaemia Comparator Evidence"/>
</entry>
</section>
<section>
<title value="Result With Treatment--Observed"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-intervention-alone"/>
<display value="Result with intervention alone"/>
</coding>
</code>
<text>
<status value="empty"/>
<div xmlns ="http://www.w3.org/1999/xhtml">[No data]</div>
</text>
</section>
<section>
<title value="Result With Treatment--Derived"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-intervention-alone-calculated"/>
<display value="Result with intervention alone (calculated)"/>
</coding>
<text
value="result with intervention with calculated value derived from the control group and effect estimate"/>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">1.5%</div>
</text>
<entry>🔗
<reference value="Evidence/236976"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313963-comparator-only-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Serious hyperglycaemia Comparator Evidence"/>
</entry>
<entry>🔗
<reference value="Evidence/236975"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313963-comparative-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Serious hyperglycaemia with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes"/>
</entry>
</section>
<section>
<title value="Effect Estimate"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-intervention-vs-comparator"/>
<display value="Result with intervention vs. comparator"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">Risk Difference 0.5% ( -0.2% to 1.9%); Odds Ratio 1.48 ( 0.75 to 2.93)</div>
</text>
<entry>🔗
<reference value="Evidence/236975"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313963-comparative-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Serious hyperglycaemia with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes"/>
</entry>
</section>
<section>
<title value="Certainty of Evidence"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="certainty-of-evidence"/>
<display value="Certainty of Evidence"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">High certainty</div>
</text>
<entry>🔗
<reference value="Evidence/236975"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313963-comparative-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Serious hyperglycaemia with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes"/>
</entry>
</section>
<section>
<title value="Assertion"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="assertion"/>
<display value="Assertion"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">There is no important difference between SGLT2 inhibitors and GLP-1 receptor agonists on the risk of serious hyperglycaemia.</div>
</text>
<entry>🔗
<reference value="Evidence/236975"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313963-comparative-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Serious hyperglycaemia with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes"/>
</entry>
</section>
</section>
<section>
<title value="Genital infection"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="summary-of-findings-entry-for-a-single-outcome"/>
<display value="Summary of findings entry for a single outcome"/>
</coding>
</code>
<focus>🔗
<reference value="EvidenceVariable/236977"/>
<type value="EvidenceVariable"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value value="MAGIC-5288-j1Wqrn-313964"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display value="OutcomeDefinition: Genital infection"/>
</focus>
<text>
<status value="empty"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p>[No data.]</p></div>
</text>
<section>
<title value="Outcome"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="outcome-measure"/>
<display value="Outcome Measure"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">Genital infection</div>
</text>
<entry>🔗
<reference value="EvidenceVariable/236977"/>
<type value="EvidenceVariable"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value value="MAGIC-5288-j1Wqrn-313964"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display value="OutcomeDefinition: Genital infection"/>
</entry>
</section>
<section>
<title value="Sample Size"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="sample-size"/>
<display value="Sample Size"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">2 studies, 1282 participants</div>
</text>
<entry>🔗
<reference value="Evidence/236978"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313964-comparative-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Genital infection with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes"/>
</entry>
</section>
<section>
<title value="Result Without Treatment"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-comparator-alone"/>
<display value="Result with comparator alone"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">5%</div>
</text>
<entry>🔗
<reference value="Evidence/236979"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313964-comparator-only-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Genital infection Comparator Evidence"/>
</entry>
</section>
<section>
<title value="Result With Treatment--Observed"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-intervention-alone"/>
<display value="Result with intervention alone"/>
</coding>
</code>
<text>
<status value="empty"/>
<div xmlns ="http://www.w3.org/1999/xhtml">[No data]</div>
</text>
</section>
<section>
<title value="Result With Treatment--Derived"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-intervention-alone-calculated"/>
<display value="Result with intervention alone (calculated)"/>
</coding>
<text
value="result with intervention with calculated value derived from the control group and effect estimate"/>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">20.8%</div>
</text>
<entry>🔗
<reference value="Evidence/236979"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313964-comparator-only-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Genital infection Comparator Evidence"/>
</entry>
<entry>🔗
<reference value="Evidence/236978"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313964-comparative-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Genital infection with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes"/>
</entry>
</section>
<section>
<title value="Effect Estimate"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-intervention-vs-comparator"/>
<display value="Result with intervention vs. comparator"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">Risk Difference 15.8% ( 6.4% to 29.9%); Odds Ratio 5 ( 2.45 to 10.2)</div>
</text>
<entry>🔗
<reference value="Evidence/236978"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313964-comparative-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Genital infection with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes"/>
</entry>
</section>
<section>
<title value="Certainty of Evidence"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="certainty-of-evidence"/>
<display value="Certainty of Evidence"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">High certainty</div>
</text>
<entry>🔗
<reference value="Evidence/236978"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313964-comparative-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Genital infection with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes"/>
</entry>
</section>
<section>
<title value="Assertion"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="assertion"/>
<display value="Assertion"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">SGLT2 inhibitors increase the risk of genital infection compared with GLP-1 receptor agonists.</div>
</text>
<entry>🔗
<reference value="Evidence/236978"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313964-comparative-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Genital infection with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes"/>
</entry>
</section>
</section>
<section>
<title value="Severe gastrointestinal events"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="summary-of-findings-entry-for-a-single-outcome"/>
<display value="Summary of findings entry for a single outcome"/>
</coding>
</code>
<focus>🔗
<reference value="EvidenceVariable/236980"/>
<type value="EvidenceVariable"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value value="MAGIC-5288-j1Wqrn-313965"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display value="OutcomeDefinition: Severe gastrointestinal events"/>
</focus>
<text>
<status value="empty"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p>[No data.]</p></div>
</text>
<section>
<title value="Outcome"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="outcome-measure"/>
<display value="Outcome Measure"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">Severe gastrointestinal events</div>
</text>
<entry>🔗
<reference value="EvidenceVariable/236980"/>
<type value="EvidenceVariable"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value value="MAGIC-5288-j1Wqrn-313965"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display value="OutcomeDefinition: Severe gastrointestinal events"/>
</entry>
</section>
<section>
<title value="Sample Size"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="sample-size"/>
<display value="Sample Size"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">7 studies, 24638 participants</div>
</text>
<entry>🔗
<reference value="Evidence/236981"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313965-comparative-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Severe gastrointestinal events with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes"/>
</entry>
</section>
<section>
<title value="Result Without Treatment"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-comparator-alone"/>
<display value="Result with comparator alone"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">4.4%</div>
</text>
<entry>🔗
<reference value="Evidence/236982"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313965-comparator-only-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Severe gastrointestinal events Comparator Evidence"/>
</entry>
</section>
<section>
<title value="Result With Treatment--Observed"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-intervention-alone"/>
<display value="Result with intervention alone"/>
</coding>
</code>
<text>
<status value="empty"/>
<div xmlns ="http://www.w3.org/1999/xhtml">[No data]</div>
</text>
</section>
<section>
<title value="Result With Treatment--Derived"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-intervention-alone-calculated"/>
<display value="Result with intervention alone (calculated)"/>
</coding>
<text
value="result with intervention with calculated value derived from the control group and effect estimate"/>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">10.2%</div>
</text>
<entry>🔗
<reference value="Evidence/236982"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313965-comparator-only-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Severe gastrointestinal events Comparator Evidence"/>
</entry>
<entry>🔗
<reference value="Evidence/236981"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313965-comparative-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Severe gastrointestinal events with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes"/>
</entry>
</section>
<section>
<title value="Effect Estimate"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-intervention-vs-comparator"/>
<display value="Result with intervention vs. comparator"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">Risk Difference 5.8% ( 0.9% to 14.2%); Odds Ratio 2.46 ( 1.22 to 4.97)</div>
</text>
<entry>🔗
<reference value="Evidence/236981"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313965-comparative-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Severe gastrointestinal events with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes"/>
</entry>
</section>
<section>
<title value="Certainty of Evidence"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="certainty-of-evidence"/>
<display value="Certainty of Evidence"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">Very low certainty</div>
</text>
<entry>🔗
<reference value="Evidence/236981"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313965-comparative-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Severe gastrointestinal events with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes"/>
</entry>
</section>
<section>
<title value="Assertion"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="assertion"/>
<display value="Assertion"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">GLP-1 receptor agonists may increase the risk of severe gastrointestinal events compared with SGLT2 inhibitors.</div>
</text>
<entry>🔗
<reference value="Evidence/236981"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-dichotomous-outcome-313965-comparative-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Severe gastrointestinal events with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes"/>
</entry>
</section>
</section>
<section>
<title value="Health-related quality of life"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="summary-of-findings-entry-for-a-single-outcome"/>
<display value="Summary of findings entry for a single outcome"/>
</coding>
</code>
<focus>🔗
<reference value="EvidenceVariable/236983"/>
<type value="EvidenceVariable"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value value="MAGIC-5288-j1Wqrn-109587"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display value="OutcomeDefinition: Health-related quality of life"/>
</focus>
<text>
<status value="empty"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p>[No data.]</p></div>
</text>
<section>
<title value="Outcome"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="outcome-measure"/>
<display value="Outcome Measure"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">Health-related quality of life</div>
</text>
<entry>🔗
<reference value="EvidenceVariable/236983"/>
<type value="EvidenceVariable"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value value="MAGIC-5288-j1Wqrn-109587"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display value="OutcomeDefinition: Health-related quality of life"/>
</entry>
</section>
<section>
<title value="Sample Size"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="sample-size"/>
<display value="Sample Size"/>
</coding>
</code>
<text>
<status value="empty"/>
<div xmlns="http://www.w3.org/1999/xhtml">[No sample size data found.]</div>
</text>
<entry>🔗
<reference value="Evidence/236984"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-continuous-outcome-109587-comparative-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Health-related quality of life with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes"/>
</entry>
</section>
<section>
<title value="Result Without Treatment"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-comparator-alone"/>
<display value="Result with comparator alone"/>
</coding>
</code>
<text>
<status value="empty"/>
<div xmlns="http://www.w3.org/1999/xhtml">[Not a proportion.]
</text>
<entry>🔗
<reference value="Evidence/236985"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-continuous-outcome-109587-comparator-only-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Health-related quality of life Comparator Evidence"/>
</entry>
</section>
<section>
<title value="Result With Treatment--Observed"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-intervention-alone"/>
<display value="Result with intervention alone"/>
</coding>
</code>
<text>
<status value="empty"/>
<div xmlns ="http://www.w3.org/1999/xhtml">[No data]</div>
</text>
</section>
<section>
<title value="Result With Treatment--Derived"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-intervention-alone-calculated"/>
<display value="Result with intervention alone (calculated)"/>
</coding>
<text
value="result with intervention with calculated value derived from the control group and effect estimate"/>
</code>
<text>
<status value="generated"/>
<div xmlns ="http://www.w3.org/1999/xhtml">[Not a proportion.]</div></div>
</text>
<entry>🔗
<reference value="Evidence/236985"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-continuous-outcome-109587-comparator-only-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Health-related quality of life Comparator Evidence"/>
</entry>
<entry>🔗
<reference value="Evidence/236984"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-continuous-outcome-109587-comparative-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Health-related quality of life with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes"/>
</entry>
</section>
<section>
<title value="Effect Estimate"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-intervention-vs-comparator"/>
<display value="Result with intervention vs. comparator"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">Standardized Mean Difference 0.01 ( -0.19 to 0.2)</div>
</text>
<entry>🔗
<reference value="Evidence/236984"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-continuous-outcome-109587-comparative-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Health-related quality of life with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes"/>
</entry>
</section>
<section>
<title value="Certainty of Evidence"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="certainty-of-evidence"/>
<display value="Certainty of Evidence"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">Low certainty</div>
</text>
<entry>🔗
<reference value="Evidence/236984"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-continuous-outcome-109587-comparative-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Health-related quality of life with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes"/>
</entry>
</section>
<section>
<title value="Assertion"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="assertion"/>
<display value="Assertion"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">There may be no important difference between SGLT2 inhibitors and GLP-1 receptor agonists on health-related quality of life.</div>
</text>
<entry>🔗
<reference value="Evidence/236984"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-continuous-outcome-109587-comparative-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Health-related quality of life with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes"/>
</entry>
</section>
</section>
<section>
<title value="Body weight"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="summary-of-findings-entry-for-a-single-outcome"/>
<display value="Summary of findings entry for a single outcome"/>
</coding>
</code>
<focus>🔗
<reference value="EvidenceVariable/236986"/>
<type value="EvidenceVariable"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value value="MAGIC-5288-j1Wqrn-109588"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display value="OutcomeDefinition: Body weight"/>
</focus>
<text>
<status value="empty"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p>[No data.]</p></div>
</text>
<section>
<title value="Outcome"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="outcome-measure"/>
<display value="Outcome Measure"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">Body weight</div>
</text>
<entry>🔗
<reference value="EvidenceVariable/236986"/>
<type value="EvidenceVariable"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value value="MAGIC-5288-j1Wqrn-109588"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display value="OutcomeDefinition: Body weight"/>
</entry>
</section>
<section>
<title value="Sample Size"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="sample-size"/>
<display value="Sample Size"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">2 studies, 1139 participants</div>
</text>
<entry>🔗
<reference value="Evidence/236987"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-continuous-outcome-109588-comparative-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Body weight with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes"/>
</entry>
</section>
<section>
<title value="Result Without Treatment"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-comparator-alone"/>
<display value="Result with comparator alone"/>
</coding>
</code>
<text>
<status value="empty"/>
<div xmlns="http://www.w3.org/1999/xhtml">[Not a proportion.]
</text>
<entry>🔗
<reference value="Evidence/236988"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-continuous-outcome-109588-comparator-only-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Body weight Comparator Evidence"/>
</entry>
</section>
<section>
<title value="Result With Treatment--Observed"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-intervention-alone"/>
<display value="Result with intervention alone"/>
</coding>
</code>
<text>
<status value="empty"/>
<div xmlns ="http://www.w3.org/1999/xhtml">[No data]</div>
</text>
</section>
<section>
<title value="Result With Treatment--Derived"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-intervention-alone-calculated"/>
<display value="Result with intervention alone (calculated)"/>
</coding>
<text
value="result with intervention with calculated value derived from the control group and effect estimate"/>
</code>
<text>
<status value="generated"/>
<div xmlns ="http://www.w3.org/1999/xhtml">[Not a proportion.]</div></div>
</text>
<entry>🔗
<reference value="Evidence/236988"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-continuous-outcome-109588-comparator-only-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Body weight Comparator Evidence"/>
</entry>
<entry>🔗
<reference value="Evidence/236987"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-continuous-outcome-109588-comparative-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Body weight with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes"/>
</entry>
</section>
<section>
<title value="Effect Estimate"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-intervention-vs-comparator"/>
<display value="Result with intervention vs. comparator"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">Mean Difference -0.47 Kg ( -0.09 Kg to -0.85 Kg)</div>
</text>
<entry>🔗
<reference value="Evidence/236987"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-continuous-outcome-109588-comparative-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Body weight with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes"/>
</entry>
</section>
<section>
<title value="Certainty of Evidence"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="certainty-of-evidence"/>
<display value="Certainty of Evidence"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">Moderate certainty</div>
</text>
<entry>🔗
<reference value="Evidence/236987"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-continuous-outcome-109588-comparative-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Body weight with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes"/>
</entry>
</section>
<section>
<title value="Assertion"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="assertion"/>
<display value="Assertion"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">SGLT2 inhibitors probably reduce body weight compared with GLP-1 receptor agonists.</div>
</text>
<entry>🔗
<reference value="Evidence/236987"/>
<type value="Evidence"/>
<identifier>
<type>
<text value="FEvIR Linking Identifier"/>
</type>
<system value="https://fevir.net/FLI"/>
<value
value="MAGIC-5288-j1Wqrn-continuous-outcome-109588-comparative-evidence"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<display
value="MAGIC-derived Evidence: Body weight with SGLT2 inhibitors vs. GLP-1 RA in Adults with type 2 diabetes"/>
</entry>
</section>
</section>
</section>
</Composition>
IG © 2024+ HL7 International / Clinical Decision Support. Package hl7.fhir.uv.ebm#2.0.0-ballot based on FHIR 6.0.0-ballot2. Generated 2024-11-21
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