Evidence Based Medicine on FHIR Implementation Guide
2.0.0-ballot - ballot
Evidence Based Medicine on FHIR Implementation Guide
2.0.0-ballot - ballot
Evidence Based Medicine on FHIR Implementation Guide, published by HL7 International / Clinical Decision Support. This guide is not an authorized publication; it is the continuous build for version 2.0.0-ballot built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/ebm/ and changes regularly. See the Directory of published versions
| Active as of 2024-11-21 |
@prefix fhir: <http://hl7.org/fhir/> . @prefix owl: <http://www.w3.org/2002/07/owl#> . @prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> . @prefix xsd: <http://www.w3.org/2001/XMLSchema#> . # - resource ------------------------------------------------------------------- a fhir:Citation ; fhir:nodeRole fhir:treeRoot ; fhir:id [ fhir:v "267246"] ; # fhir:meta [ fhir:versionId [ fhir:v "1" ] ; fhir:lastUpdated [ fhir:v "2024-08-01T12:35:46.147Z"^^xsd:dateTime ] ; ( fhir:profile [ fhir:v "http://hl7.org/fhir/uv/ebm/StructureDefinition/journal-article-citation"^^xsd:anyURI ; fhir:link <http://hl7.org/fhir/uv/ebm/StructureDefinition/journal-article-citation> ] ) ] ; # fhir:text [ fhir:status [ fhir:v "generated" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: Citation 267246</b></p><a name=\"267246\"> </a><a name=\"hc267246\"> </a><a name=\"267246-en-US\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">version: 1; Last updated: 2024-08-01 12:35:46+0000</p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-journal-article-citation.html\">JournalArticleCitation</a></p></div><p><b>url</b>: <a href=\"Citation-267246.html\">Citation 11232013 Rosiglitazone monotherapy is effective in patients with type 2 diabetes.</a></p><p><b>identifier</b>: FEvIR Object Identifier/267246, <code>https://pubmed.ncbi.nlm.nih.gov</code>/11232013, <a href=\"http://terminology.hl7.org/6.1.0/NamingSystem-uri.html\" title=\"As defined by RFC 3986 (http://www.ietf.org/rfc/rfc3986.txt)(with many schemes defined in many RFCs). For OIDs and UUIDs, use the URN form (urn:oid:(note: lowercase) and urn:uuid:). See http://www.ietf.org/rfc/rfc3001.txt and http://www.ietf.org/rfc/rfc4122.txt \r\n\r\nThis oid is used as an identifier II.root to indicate the the extension is an absolute URI (technically, an IRI). Typically, this is used for OIDs and GUIDs. Note that when this OID is used with OIDs and GUIDs, the II.extension should start with urn:oid or urn:uuid: \r\n\r\nNote that this OID is created to aid with interconversion between CDA and FHIR - FHIR uses urn:ietf:rfc:3986 as equivalent to this OID. URIs as identifiers appear more commonly in FHIR.\r\n\r\nThis OID may also be used in CD.codeSystem.\">Uniform Resource Identifier (URI)</a>/urn:oid:2.16.840.1.113883.4.642.40.44.15.44</p><p><b>version</b>: 2.0.0-ballot</p><p><b>title</b>: 11232013 Rosiglitazone monotherapy is effective in patients with type 2 diabetes.</p><p><b>status</b>: Active</p><p><b>date</b>: 2024-11-21 14:09:14+0000</p><p><b>publisher</b>: HL7 International / Clinical Decision Support</p><p><b>contact</b>: HL7 International / Clinical Decision Support: <a href=\"http://www.hl7.org/Special/committees/dss\">http://www.hl7.org/Special/committees/dss</a></p><p><b>description</b>: </p><div><p>This Citation Resource is referenced in an example for the EBMonFHIR Implementation Guide.</p>\n</div><h3>UseContexts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"http://hl7.org/fhir/R5/codesystem-citation-classification-type.html#citation-classification-type-fevir-platform-use\">Citation Classification Type fevir-platform-use</a>: FEvIR Platform Use</td><td><span title=\"Codes:{http://hl7.org/fhir/citation-artifact-classifier medline-base}\">Medline Base</span></td></tr></table><p><b>jurisdiction</b>: <span title=\"Codes:{http://unstats.un.org/unsd/methods/m49/m49.htm 001}\">World</span></p><p><b>copyright</b>: </p><div><p>https://creativecommons.org/licenses/by-nc-sa/4.0/</p>\n</div><p><b>approvalDate</b>: 2001-04-12</p><p><b>lastReviewDate</b>: 2018-11-30</p><p><b>author</b>: Computable Publishing®: MEDLINE-to-FEvIR Converter: </p><blockquote><p><b>classification</b></p><p><b>type</b>: <span title=\"Codes:{http://hl7.org/fhir/citation-classification-type citation-source}\">Citation Source</span></p><p><b>classifier</b>: <span title=\"Codes:\">MEDLINE</span></p></blockquote><blockquote><p><b>classification</b></p><p><b>type</b>: <span title=\"Codes:{http://hl7.org/fhir/citation-classification-type medline-owner}\">MEDLINE Citation Owner</span></p><p><b>classifier</b>: <span title=\"Codes:{https://www.nlm.nih.gov/bsd/licensee/elements_descriptions.html#owner_value NLM}\">National Library of Medicine, Index Section</span></p></blockquote><p><b>currentState</b>: <span title=\"Codes:{http://hl7.org/fhir/citation-status-type medline-medline}\">Medline Citation Status of Medline</span>, <span title=\"Codes:{http://hl7.org/fhir/citation-status-type pubmed-publication-status-ppublish}\">PubMed PublicationStatus of ppublish</span></p><blockquote><p><b>statusDate</b></p><p><b>activity</b>: <span title=\"Codes:{http://hl7.org/fhir/citation-status-type pubmed-pubstatus-pubmed}\">PubMed Pubstatus of Pubmed</span></p><p><b>period</b>: ?? --> 2001-03-07 10:00:00+0000</p></blockquote><blockquote><p><b>statusDate</b></p><p><b>activity</b>: <span title=\"Codes:{http://hl7.org/fhir/citation-status-type pubmed-pubstatus-medline}\">PubMed Pubstatus of Medline</span></p><p><b>period</b>: ?? --> 2001-04-17 10:01:00+0000</p></blockquote><blockquote><p><b>statusDate</b></p><p><b>activity</b>: <span title=\"Codes:{http://hl7.org/fhir/citation-status-type pubmed-pubstatus-entrez}\">PubMed Pubstatus of Entrez</span></p><p><b>period</b>: ?? --> 2001-03-07 10:00:00+0000</p></blockquote><blockquote><p><b>citedArtifact</b></p><p><b>identifier</b>: <code>https://pubmed.ncbi.nlm.nih.gov</code>/11232013, <code>https://doi.org</code>/10.1210/jcem.86.1.7157</p><h3>Titles</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Language</b></td><td><b>Text</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://hl7.org/fhir/title-type primary}\">Primary title</span></td><td><span title=\"Codes:{urn:ietf:bcp:47 en}\">English</span></td><td><div><p>Rosiglitazone monotherapy is effective in patients with type 2 diabetes.</p>\n</div></td></tr></table><h3>Abstracts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Text</b></td></tr><tr><td style=\"display: none\">*</td><td><div><p>This study evaluated the efficacy and safety of rosiglitazone monotherapy in patients with type 2 diabetes. After a 4-week placebo run-in period, 493 patients with type 2 diabetes were randomized to receive rosiglitazone [2 or 4 mg twice daily (bd)] or placebo for 26 weeks. The primary end point was change in hemoglobin A(1c); other variables assessed included fasting plasma glucose, fructosamine, endogenous insulin secretion, urinary albumin excretion, serum lipids, and adverse events. Rosiglitazone (2 and 4 mg bd) decreased mean hemoglobin A(1c) relative to placebo by 1.2 and 1.5 percentage points, respectively, and reduced fasting plasma glucose concentrations relative to placebo by 3.22 and 4.22 mmol/L, respectively. Fasting plasma insulin and insulin precursor molecules decreased significantly. Homeostasis model assessment estimates indicate that rosiglitazone (2 and 4 mg bd) reduced insulin resistance by 16.0% and 24.6%, respectively, and improved ss-cell function over baseline by 49.5% and 60.0%, respectively. Urinary albumin excretion decreased significantly in the rosiglitazone (4 mg bd) group. There was no increase in adverse events with rosiglitazone. In the short-term, rosiglitazone is an insulin sensitizer that is effective and safe as monotherapy in patients with type 2 diabetes who are inadequately controlled by lifestyle interventions.</p>\n</div></td></tr></table><blockquote><p><b>relatesTo</b></p><p><b>type</b>: correction-in</p><p><b>classifier</b>: <span title=\"Codes:{https://meshb.nlm.nih.gov/ D016425}\">Published Erratum</span></p><p><b>citation</b>: </p><div><p>J Clin Endocrinol Metab 2001 Apr;86(4):1659</p>\n</div></blockquote><blockquote><p><b>relatesTo</b></p><p><b>type</b>: correction-in</p><p><b>classifier</b>: <span title=\"Codes:{https://meshb.nlm.nih.gov/ D016425}\">Published Erratum</span></p><p><b>citation</b>: </p><div><p>J Clin Endocrinol Metab. 2002 Feb;2(1):iv.</p>\n</div></blockquote><blockquote><p><b>publicationForm</b></p><blockquote><p><b>publishedIn</b></p><p><b>type</b>: <span title=\"Codes:{http://hl7.org/fhir/published-in-type D020492}\">Periodical</span></p><p><b>identifier</b>: Print ISSN Type/0021-972X, ISOAbbreviation/J Clin Endocrinol Metab, ISSN Linking/0021-972X, Medline Title Abbreviation/J Clin Endocrinol Metab, NLM Unique ID/0375362</p><p><b>title</b>: The Journal of clinical endocrinology and metabolism</p><p><b>publisherLocation</b>: United States</p></blockquote><p><b>citedMedium</b>: <span title=\"Codes:{http://hl7.org/fhir/cited-medium print}\">Print</span></p><p><b>volume</b>: 86</p><p><b>issue</b>: 1</p><p><b>articleDate</b>: 2001-01</p><p><b>publicationDateText</b>: 2001-Jan</p><p><b>language</b>: <span title=\"Codes:{urn:ietf:bcp:47 en}\">English</span></p><p><b>pageString</b>: 280-8</p></blockquote><h3>WebLocations</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Classifier</b></td><td><b>Url</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://hl7.org/fhir/artifact-url-classifier abstract}\">Abstract</span></td><td><a href=\"https://pubmed.ncbi.nlm.nih.gov/11232013/\">https://pubmed.ncbi.nlm.nih.gov/11232013/</a></td></tr></table><blockquote><p><b>classification</b></p><p><b>type</b>: <span title=\"Codes:{http://hl7.org/fhir/cited-artifact-classification-type publishing-model}\">Publishing Model</span></p><p><b>classifier</b>: <span title=\"Codes:{http://hl7.org/fhir/citation-artifact-classifier Print}\">Print</span></p></blockquote><blockquote><p><b>classification</b></p><p><b>type</b>: <span title=\"Codes:{http://hl7.org/fhir/cited-artifact-classification-type chemical}\">Chemical</span></p><p><b>classifier</b>: <span title=\"Codes:{https://meshb.nlm.nih.gov/ D001786}\">Blood Glucose</span>, <span title=\"Codes:{https://meshb.nlm.nih.gov/ D007004}\">Hypoglycemic Agents</span>, <span title=\"Codes:{https://meshb.nlm.nih.gov/ D013844}\">Thiazoles</span>, <span title=\"Codes:{https://meshb.nlm.nih.gov/ D045162}\">Thiazolidinediones</span>, <span title=\"Codes:{https://www.cas.org/support/documentation/chemical-substances 05V02F2KDG}, {https://meshb.nlm.nih.gov/ D000077154}\">Rosiglitazone</span></p></blockquote><blockquote><p><b>classification</b></p><p><b>type</b>: <span title=\"Codes:{http://hl7.org/fhir/cited-artifact-classification-type mesh-heading}\">MeSH heading</span></p><p><b>artifactAssessment</b>: <a href=\"#hc267246/meshHeading0\">ArtifactAssessment: artifact[x] = this resource</a></p></blockquote><blockquote><p><b>classification</b></p><p><b>type</b>: <span title=\"Codes:{http://hl7.org/fhir/cited-artifact-classification-type publication-type}\">Publication type</span></p><p><b>classifier</b>: <span title=\"Codes:{https://meshb.nlm.nih.gov/ D016430}\">Clinical Trial</span>, <span title=\"Codes:{https://meshb.nlm.nih.gov/ D016428}\">Journal Article</span>, <span title=\"Codes:{https://meshb.nlm.nih.gov/ D016448}\">Multicenter Study</span>, <span title=\"Codes:{https://meshb.nlm.nih.gov/ D016449}\">Randomized Controlled Trial</span></p></blockquote><blockquote><p><b>classification</b></p><p><b>type</b>: <span title=\"Codes:{http://hl7.org/fhir/cited-artifact-classification-type knowledge-artifact-type}\">Knowledge Artifact Type</span></p><p><b>classifier</b>: <span title=\"Codes:{http://hl7.org/fhir/citation-artifact-classifier D016428}\">Journal Article</span></p><p><b>artifactAssessment</b>: Classifier added by Computable Publishing LLC</p></blockquote><blockquote><p><b>classification</b></p><p><b>type</b>: <span title=\"Codes:{http://hl7.org/fhir/cited-artifact-classification-type citation-subset}\">Citation subset</span></p><p><b>classifier</b>: <span title=\"Codes:{https://www.nlm.nih.gov/bsd/licensee/elements_descriptions.html#citationsubset IM}\">IM</span></p></blockquote><blockquote><p><b>contributorship</b></p><p><b>complete</b>: true</p><blockquote><p><b>entry</b></p><p><b>contributor</b>: <a href=\"#hc267246/contributor0\">Lebovitz HE</a></p><p><b>forenameInitials</b>: HE</p><p><b>affiliation</b>: Department of Medicine, State University of New York, Brooklyn, New York 11203, USA. hlebovitz@attglobal.net</p></blockquote><blockquote><p><b>entry</b></p><p><b>contributor</b>: <a href=\"#hc267246/contributor1\">Dole JF</a></p><p><b>forenameInitials</b>: JF</p></blockquote><blockquote><p><b>entry</b></p><p><b>contributor</b>: <a href=\"#hc267246/contributor2\">Patwardhan R</a></p><p><b>forenameInitials</b>: R</p></blockquote><blockquote><p><b>entry</b></p><p><b>contributor</b>: <a href=\"#hc267246/contributor3\">Rappaport EB</a></p><p><b>forenameInitials</b>: EB</p></blockquote><blockquote><p><b>entry</b></p><p><b>contributor</b>: <a href=\"#hc267246/contributor4\">Freed MI</a></p><p><b>forenameInitials</b>: MI</p></blockquote><blockquote><p><b>entry</b></p><p><b>contributor</b>: <a href=\"#hc267246/contributor5\">Rosiglitazone Clinical Trials Study Group</a></p></blockquote></blockquote></blockquote><hr/><blockquote><p class=\"res-header-id\"><b>Generated Narrative: Practitioner #contributor0</b></p><a name=\"267246/contributor0\"> </a><a name=\"hc267246/contributor0\"> </a><a name=\"267246/contributor0-en-US\"> </a><p><b>name</b>: H E Lebovitz </p></blockquote><hr/><blockquote><p class=\"res-header-id\"><b>Generated Narrative: Practitioner #contributor1</b></p><a name=\"267246/contributor1\"> </a><a name=\"hc267246/contributor1\"> </a><a name=\"267246/contributor1-en-US\"> </a><p><b>name</b>: J F Dole </p></blockquote><hr/><blockquote><p class=\"res-header-id\"><b>Generated Narrative: Practitioner #contributor2</b></p><a name=\"267246/contributor2\"> </a><a name=\"hc267246/contributor2\"> </a><a name=\"267246/contributor2-en-US\"> </a><p><b>name</b>: R Patwardhan </p></blockquote><hr/><blockquote><p class=\"res-header-id\"><b>Generated Narrative: Practitioner #contributor3</b></p><a name=\"267246/contributor3\"> </a><a name=\"hc267246/contributor3\"> </a><a name=\"267246/contributor3-en-US\"> </a><p><b>name</b>: E B Rappaport </p></blockquote><hr/><blockquote><p class=\"res-header-id\"><b>Generated Narrative: Practitioner #contributor4</b></p><a name=\"267246/contributor4\"> </a><a name=\"hc267246/contributor4\"> </a><a name=\"267246/contributor4-en-US\"> </a><p><b>name</b>: M I Freed </p></blockquote><hr/><blockquote><p class=\"res-header-id\"><b>Generated Narrative: Organization #contributor5</b></p><a name=\"267246/contributor5\"> </a><a name=\"hc267246/contributor5\"> </a><a name=\"267246/contributor5-en-US\"> </a><p><b>name</b>: Rosiglitazone Clinical Trials Study Group</p></blockquote><hr/><blockquote><p class=\"res-header-id\"><b>Generated Narrative: ArtifactAssessment #meshHeading0</b></p><a name=\"267246/meshHeading0\"> </a><a name=\"hc267246/meshHeading0\"> </a><a name=\"267246/meshHeading0-en-US\"> </a><p><b>artifact</b>: <a href=\"#hc267246\">Citation 11232013 Rosiglitazone monotherapy is effective in patients with type 2 diabetes.</a></p><blockquote><p><b>content</b></p><p><b>informationType</b>: Classifier</p><p><b>type</b>: <span title=\"Codes:{http://hl7.org/fhir/cited-artifact-classification-type mesh-heading}\">components (if present) include qualifier codings</span></p><p><b>classifier</b>: <span title=\"Codes:{https://meshb.nlm.nih.gov/ D000368}\">Aged</span></p><p><b>freeToShare</b>: true</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:\">qualifier</span></td><td><span title=\"Codes:\">is not a major topic</span></td></tr></table></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: Classifier</p><p><b>type</b>: <span title=\"Codes:{http://hl7.org/fhir/cited-artifact-classification-type mesh-heading}\">components (if present) include qualifier codings</span></p><p><b>classifier</b>: <span title=\"Codes:{https://meshb.nlm.nih.gov/ D000369}\">Aged, 80 and over</span></p><p><b>freeToShare</b>: true</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:\">qualifier</span></td><td><span title=\"Codes:\">is not a major topic</span></td></tr></table></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: Classifier</p><p><b>type</b>: <span title=\"Codes:{http://hl7.org/fhir/cited-artifact-classification-type mesh-heading}\">components (if present) include qualifier codings</span></p><p><b>classifier</b>: <span title=\"Codes:{https://meshb.nlm.nih.gov/ D001786}\">Blood Glucose</span></p><p><b>freeToShare</b>: true</p><blockquote><p><b>component</b></p><p><b>type</b>: <span title=\"Codes:\">qualifier</span></p><p><b>classifier</b>: <span title=\"Codes:\">is not a major topic</span></p></blockquote><blockquote><p><b>component</b></p><p><b>type</b>: <span title=\"Codes:\">qualifier</span></p><p><b>classifier</b>: <span title=\"Codes:{https://meshb.nlm.nih.gov/ Q000032}\">analysis</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:\">is Major topic</span></td><td><span title=\"Codes:{https://ncithesaurus.nci.nih.gov/ncitbrowser C49487}\">No</span></td></tr></table></blockquote></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: Classifier</p><p><b>type</b>: <span title=\"Codes:{http://hl7.org/fhir/cited-artifact-classification-type mesh-heading}\">components (if present) include qualifier codings</span></p><p><b>classifier</b>: <span title=\"Codes:{https://meshb.nlm.nih.gov/ D003924}\">Diabetes Mellitus, Type 2</span></p><p><b>freeToShare</b>: true</p><blockquote><p><b>component</b></p><p><b>type</b>: <span title=\"Codes:\">qualifier</span></p><p><b>classifier</b>: <span title=\"Codes:\">is not a major topic</span></p></blockquote><blockquote><p><b>component</b></p><p><b>type</b>: <span title=\"Codes:\">qualifier</span></p><p><b>classifier</b>: <span title=\"Codes:{https://meshb.nlm.nih.gov/ Q000097}\">blood</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:\">is Major topic</span></td><td><span title=\"Codes:{https://ncithesaurus.nci.nih.gov/ncitbrowser C49487}\">No</span></td></tr></table></blockquote><blockquote><p><b>component</b></p><p><b>type</b>: <span title=\"Codes:\">qualifier</span></p><p><b>classifier</b>: <span title=\"Codes:{https://meshb.nlm.nih.gov/ Q000188}\">drug therapy</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:\">is Major topic</span></td><td><span title=\"Codes:{https://ncithesaurus.nci.nih.gov/ncitbrowser C49488}\">Yes</span></td></tr></table></blockquote><blockquote><p><b>component</b></p><p><b>type</b>: <span title=\"Codes:\">qualifier</span></p><p><b>classifier</b>: <span title=\"Codes:{https://meshb.nlm.nih.gov/ Q000503}\">physiopathology</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:\">is Major topic</span></td><td><span title=\"Codes:{https://ncithesaurus.nci.nih.gov/ncitbrowser C49487}\">No</span></td></tr></table></blockquote></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: Classifier</p><p><b>type</b>: <span title=\"Codes:{http://hl7.org/fhir/cited-artifact-classification-type mesh-heading}\">components (if present) include qualifier codings</span></p><p><b>classifier</b>: <span title=\"Codes:{https://meshb.nlm.nih.gov/ D004311}\">Double-Blind Method</span></p><p><b>freeToShare</b>: true</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:\">qualifier</span></td><td><span title=\"Codes:\">is not a major topic</span></td></tr></table></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: Classifier</p><p><b>type</b>: <span title=\"Codes:{http://hl7.org/fhir/cited-artifact-classification-type mesh-heading}\">components (if present) include qualifier codings</span></p><p><b>classifier</b>: <span title=\"Codes:{https://meshb.nlm.nih.gov/ D005260}\">Female</span></p><p><b>freeToShare</b>: true</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:\">qualifier</span></td><td><span title=\"Codes:\">is not a major topic</span></td></tr></table></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: Classifier</p><p><b>type</b>: <span title=\"Codes:{http://hl7.org/fhir/cited-artifact-classification-type mesh-heading}\">components (if present) include qualifier codings</span></p><p><b>classifier</b>: <span title=\"Codes:{https://meshb.nlm.nih.gov/ D006801}\">Humans</span></p><p><b>freeToShare</b>: true</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:\">qualifier</span></td><td><span title=\"Codes:\">is not a major topic</span></td></tr></table></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: Classifier</p><p><b>type</b>: <span title=\"Codes:{http://hl7.org/fhir/cited-artifact-classification-type mesh-heading}\">components (if present) include qualifier codings</span></p><p><b>classifier</b>: <span title=\"Codes:{https://meshb.nlm.nih.gov/ D007004}\">Hypoglycemic Agents</span></p><p><b>freeToShare</b>: true</p><blockquote><p><b>component</b></p><p><b>type</b>: <span title=\"Codes:\">qualifier</span></p><p><b>classifier</b>: <span title=\"Codes:\">is not a major topic</span></p></blockquote><blockquote><p><b>component</b></p><p><b>type</b>: <span title=\"Codes:\">qualifier</span></p><p><b>classifier</b>: <span title=\"Codes:{https://meshb.nlm.nih.gov/ Q000009}\">adverse effects</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:\">is Major topic</span></td><td><span title=\"Codes:{https://ncithesaurus.nci.nih.gov/ncitbrowser C49487}\">No</span></td></tr></table></blockquote><blockquote><p><b>component</b></p><p><b>type</b>: <span title=\"Codes:\">qualifier</span></p><p><b>classifier</b>: <span title=\"Codes:{https://meshb.nlm.nih.gov/ Q000627}\">therapeutic use</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:\">is Major topic</span></td><td><span title=\"Codes:{https://ncithesaurus.nci.nih.gov/ncitbrowser C49488}\">Yes</span></td></tr></table></blockquote></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: Classifier</p><p><b>type</b>: <span title=\"Codes:{http://hl7.org/fhir/cited-artifact-classification-type mesh-heading}\">components (if present) include qualifier codings</span></p><p><b>classifier</b>: <span title=\"Codes:{https://meshb.nlm.nih.gov/ D007515}\">Islets of Langerhans</span></p><p><b>freeToShare</b>: true</p><blockquote><p><b>component</b></p><p><b>type</b>: <span title=\"Codes:\">qualifier</span></p><p><b>classifier</b>: <span title=\"Codes:\">is not a major topic</span></p></blockquote><blockquote><p><b>component</b></p><p><b>type</b>: <span title=\"Codes:\">qualifier</span></p><p><b>classifier</b>: <span title=\"Codes:{https://meshb.nlm.nih.gov/ Q000187}\">drug effects</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:\">is Major topic</span></td><td><span title=\"Codes:{https://ncithesaurus.nci.nih.gov/ncitbrowser C49487}\">No</span></td></tr></table></blockquote><blockquote><p><b>component</b></p><p><b>type</b>: <span title=\"Codes:\">qualifier</span></p><p><b>classifier</b>: <span title=\"Codes:{https://meshb.nlm.nih.gov/ Q000503}\">physiopathology</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:\">is Major topic</span></td><td><span title=\"Codes:{https://ncithesaurus.nci.nih.gov/ncitbrowser C49487}\">No</span></td></tr></table></blockquote></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: Classifier</p><p><b>type</b>: <span title=\"Codes:{http://hl7.org/fhir/cited-artifact-classification-type mesh-heading}\">components (if present) include qualifier codings</span></p><p><b>classifier</b>: <span title=\"Codes:{https://meshb.nlm.nih.gov/ D008297}\">Male</span></p><p><b>freeToShare</b>: true</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:\">qualifier</span></td><td><span title=\"Codes:\">is not a major topic</span></td></tr></table></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: Classifier</p><p><b>type</b>: <span title=\"Codes:{http://hl7.org/fhir/cited-artifact-classification-type mesh-heading}\">components (if present) include qualifier codings</span></p><p><b>classifier</b>: <span title=\"Codes:{https://meshb.nlm.nih.gov/ D008875}\">Middle Aged</span></p><p><b>freeToShare</b>: true</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:\">qualifier</span></td><td><span title=\"Codes:\">is not a major topic</span></td></tr></table></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: Classifier</p><p><b>type</b>: <span title=\"Codes:{http://hl7.org/fhir/cited-artifact-classification-type mesh-heading}\">components (if present) include qualifier codings</span></p><p><b>classifier</b>: <span title=\"Codes:{https://meshb.nlm.nih.gov/ D000077154}\">Rosiglitazone</span></p><p><b>freeToShare</b>: true</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:\">qualifier</span></td><td><span title=\"Codes:\">is not a major topic</span></td></tr></table></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: Classifier</p><p><b>type</b>: <span title=\"Codes:{http://hl7.org/fhir/cited-artifact-classification-type mesh-heading}\">components (if present) include qualifier codings</span></p><p><b>classifier</b>: <span title=\"Codes:{https://meshb.nlm.nih.gov/ D016037}\">Single-Blind Method</span></p><p><b>freeToShare</b>: true</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:\">qualifier</span></td><td><span title=\"Codes:\">is not a major topic</span></td></tr></table></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: Classifier</p><p><b>type</b>: <span title=\"Codes:{http://hl7.org/fhir/cited-artifact-classification-type mesh-heading}\">components (if present) include qualifier codings</span></p><p><b>classifier</b>: <span title=\"Codes:{https://meshb.nlm.nih.gov/ D013844}\">Thiazoles</span></p><p><b>freeToShare</b>: true</p><blockquote><p><b>component</b></p><p><b>type</b>: <span title=\"Codes:\">qualifier</span></p><p><b>classifier</b>: <span title=\"Codes:\">is not a major topic</span></p></blockquote><blockquote><p><b>component</b></p><p><b>type</b>: <span title=\"Codes:\">qualifier</span></p><p><b>classifier</b>: <span title=\"Codes:{https://meshb.nlm.nih.gov/ Q000009}\">adverse effects</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:\">is Major topic</span></td><td><span title=\"Codes:{https://ncithesaurus.nci.nih.gov/ncitbrowser C49487}\">No</span></td></tr></table></blockquote><blockquote><p><b>component</b></p><p><b>type</b>: <span title=\"Codes:\">qualifier</span></p><p><b>classifier</b>: <span title=\"Codes:{https://meshb.nlm.nih.gov/ Q000627}\">therapeutic use</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:\">is Major topic</span></td><td><span title=\"Codes:{https://ncithesaurus.nci.nih.gov/ncitbrowser C49488}\">Yes</span></td></tr></table></blockquote></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: Classifier</p><p><b>type</b>: <span title=\"Codes:{http://hl7.org/fhir/cited-artifact-classification-type mesh-heading}\">components (if present) include qualifier codings</span></p><p><b>classifier</b>: <span title=\"Codes:{https://meshb.nlm.nih.gov/ D045162}\">Thiazolidinediones</span></p><p><b>freeToShare</b>: true</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:\">qualifier</span></td><td><span title=\"Codes:\">is Major topic</span></td></tr></table></blockquote></blockquote></div>" ] ; # fhir:contained ( [ a fhir:Practitioner ; fhir:id [ fhir:v "contributor0" ] ; ( fhir:name [ fhir:family [ fhir:v "Lebovitz" ] ; ( fhir:given [ fhir:v "H E" ] ) ] ) ] [ a fhir:Practitioner ; fhir:id [ fhir:v "contributor1" ] ; ( fhir:name [ fhir:family [ fhir:v "Dole" ] ; ( fhir:given [ fhir:v "J F" ] ) ] ) ] [ a fhir:Practitioner ; fhir:id [ fhir:v "contributor2" ] ; ( fhir:name [ fhir:family [ fhir:v "Patwardhan" ] ; ( fhir:given [ fhir:v "R" ] ) ] ) ] [ a fhir:Practitioner ; fhir:id [ fhir:v "contributor3" ] ; ( fhir:name [ fhir:family [ fhir:v "Rappaport" ] ; ( fhir:given [ fhir:v "E B" ] ) ] ) ] [ a fhir:Practitioner ; fhir:id [ fhir:v "contributor4" ] ; ( fhir:name [ fhir:family [ fhir:v "Freed" ] ; ( fhir:given [ fhir:v "M I" ] ) ] ) ] [ a fhir:Organization ; fhir:id [ fhir:v "contributor5" ] ; fhir:name [ fhir:v "Rosiglitazone Clinical Trials Study Group" ] ] [ a fhir:ArtifactAssessment ; fhir:id [ fhir:v "meshHeading0" ] ; fhir:artifact [ a fhir:Reference ; fhir:reference [ fhir:v "#" ] ; fhir:type [ fhir:v "Citation"^^xsd:anyURI ] ] ; ( fhir:content [ fhir:informationType [ fhir:v "classifier" ] ; fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/cited-artifact-classification-type"^^xsd:anyURI ] ; fhir:code [ fhir:v "mesh-heading" ] ; fhir:display [ fhir:v "MeSH heading" ] ] ) ; fhir:text [ fhir:v "components (if present) include qualifier codings" ] ] ; ( fhir:classifier [ ( fhir:coding [ fhir:system [ fhir:v "https://meshb.nlm.nih.gov/"^^xsd:anyURI ] ; fhir:code [ fhir:v "D000368" ] ; fhir:display [ fhir:v "Aged" ] ; fhir:userSelected [ fhir:v "false"^^xsd:boolean ] ] ) ] ) ; fhir:freeToShare [ fhir:v "true"^^xsd:boolean ] ; ( fhir:component [ fhir:type [ fhir:text [ fhir:v "qualifier" ] ] ; ( fhir:classifier [ fhir:text [ fhir:v "is not a major topic" ] ] ) ] ) ] [ fhir:informationType [ fhir:v "classifier" ] ; fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/cited-artifact-classification-type"^^xsd:anyURI ] ; fhir:code [ fhir:v "mesh-heading" ] ; fhir:display [ fhir:v "MeSH heading" ] ] ) ; fhir:text [ fhir:v "components (if present) include qualifier codings" ] ] ; ( fhir:classifier [ ( fhir:coding [ fhir:system [ fhir:v "https://meshb.nlm.nih.gov/"^^xsd:anyURI ] ; fhir:code [ fhir:v "D000369" ] ; fhir:display [ fhir:v "Aged, 80 and over" ] ; fhir:userSelected [ fhir:v "false"^^xsd:boolean ] ] ) ] ) ; fhir:freeToShare [ fhir:v "true"^^xsd:boolean ] ; ( fhir:component [ fhir:type [ fhir:text [ fhir:v "qualifier" ] ] ; ( fhir:classifier [ fhir:text [ fhir:v "is not a major topic" ] ] ) ] ) ] [ fhir:informationType [ fhir:v "classifier" ] ; fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/cited-artifact-classification-type"^^xsd:anyURI ] ; fhir:code [ fhir:v "mesh-heading" ] ; fhir:display [ fhir:v "MeSH heading" ] ] ) ; fhir:text [ fhir:v "components (if present) include qualifier codings" ] ] ; ( fhir:classifier [ ( fhir:coding [ fhir:system [ fhir:v "https://meshb.nlm.nih.gov/"^^xsd:anyURI ] ; fhir:code [ fhir:v "D001786" ] ; fhir:display [ fhir:v "Blood Glucose" ] ; fhir:userSelected [ fhir:v "false"^^xsd:boolean ] ] ) ] ) ; fhir:freeToShare [ fhir:v "true"^^xsd:boolean ] ; ( fhir:component [ fhir:type [ fhir:text [ fhir:v "qualifier" ] ] ; ( fhir:classifier [ fhir:text [ fhir:v "is not a major topic" ] ] ) ] [ fhir:type [ fhir:text [ fhir:v "qualifier" ] ] ; ( fhir:classifier [ ( fhir:coding [ fhir:system [ fhir:v "https://meshb.nlm.nih.gov/"^^xsd:anyURI ] ; fhir:code [ fhir:v "Q000032" ] ; fhir:display [ fhir:v "analysis" ] ] ) ] ) ; ( fhir:component [ fhir:type [ fhir:text [ fhir:v "is Major topic" ] ] ; ( fhir:classifier [ ( fhir:coding [ fhir:system [ fhir:v "https://ncithesaurus.nci.nih.gov/ncitbrowser"^^xsd:anyURI ] ; fhir:code [ fhir:v "C49487" ] ; fhir:display [ fhir:v "No" ] ] ) ] ) ] ) ] ) ] [ fhir:informationType [ fhir:v "classifier" ] ; fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/cited-artifact-classification-type"^^xsd:anyURI ] ; fhir:code [ fhir:v "mesh-heading" ] ; fhir:display [ fhir:v "MeSH heading" ] ] ) ; fhir:text [ fhir:v "components (if present) include qualifier codings" ] ] ; ( fhir:classifier [ ( fhir:coding [ fhir:system [ fhir:v "https://meshb.nlm.nih.gov/"^^xsd:anyURI ] ; fhir:code [ fhir:v "D003924" ] ; fhir:display [ fhir:v "Diabetes Mellitus, Type 2" ] ; fhir:userSelected [ fhir:v "false"^^xsd:boolean ] ] ) ] ) ; fhir:freeToShare [ fhir:v "true"^^xsd:boolean ] ; ( fhir:component [ fhir:type [ fhir:text [ fhir:v "qualifier" ] ] ; ( fhir:classifier [ fhir:text [ fhir:v "is not a major topic" ] ] ) ] [ fhir:type [ fhir:text [ fhir:v "qualifier" ] ] ; ( fhir:classifier [ ( fhir:coding [ fhir:system [ fhir:v "https://meshb.nlm.nih.gov/"^^xsd:anyURI ] ; fhir:code [ fhir:v "Q000097" ] ; fhir:display [ fhir:v "blood" ] ] ) ] ) ; ( fhir:component [ fhir:type [ fhir:text [ fhir:v "is Major topic" ] ] ; ( fhir:classifier [ ( fhir:coding [ fhir:system [ fhir:v "https://ncithesaurus.nci.nih.gov/ncitbrowser"^^xsd:anyURI ] ; fhir:code [ fhir:v "C49487" ] ; fhir:display [ fhir:v "No" ] ] ) ] ) ] ) ] [ fhir:type [ fhir:text [ fhir:v "qualifier" ] ] ; ( fhir:classifier [ ( fhir:coding [ fhir:system [ fhir:v "https://meshb.nlm.nih.gov/"^^xsd:anyURI ] ; fhir:code [ fhir:v "Q000188" ] ; fhir:display [ fhir:v "drug therapy" ] ] ) ] ) ; ( fhir:component [ fhir:type [ fhir:text [ fhir:v "is Major topic" ] ] ; ( fhir:classifier [ ( fhir:coding [ fhir:system [ fhir:v "https://ncithesaurus.nci.nih.gov/ncitbrowser"^^xsd:anyURI ] ; fhir:code [ fhir:v "C49488" ] ; fhir:display [ fhir:v "Yes" ] ] ) ] ) ] ) ] [ fhir:type [ fhir:text [ fhir:v "qualifier" ] ] ; ( fhir:classifier [ ( fhir:coding [ fhir:system [ fhir:v "https://meshb.nlm.nih.gov/"^^xsd:anyURI ] ; fhir:code [ fhir:v "Q000503" ] ; fhir:display [ fhir:v "physiopathology" ] ] ) ] ) ; ( fhir:component [ fhir:type [ fhir:text [ fhir:v "is Major topic" ] ] ; ( fhir:classifier [ ( fhir:coding [ fhir:system [ fhir:v "https://ncithesaurus.nci.nih.gov/ncitbrowser"^^xsd:anyURI ] ; fhir:code [ fhir:v "C49487" ] ; fhir:display [ fhir:v "No" ] ] ) ] ) ] ) ] ) ] [ fhir:informationType [ fhir:v "classifier" ] ; fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/cited-artifact-classification-type"^^xsd:anyURI ] ; fhir:code [ fhir:v "mesh-heading" ] ; fhir:display [ fhir:v "MeSH heading" ] ] ) ; fhir:text [ fhir:v "components (if present) include qualifier codings" ] ] ; ( fhir:classifier [ ( fhir:coding [ fhir:system [ fhir:v "https://meshb.nlm.nih.gov/"^^xsd:anyURI ] ; fhir:code [ fhir:v "D004311" ] ; fhir:display [ fhir:v "Double-Blind Method" ] ; fhir:userSelected [ fhir:v "false"^^xsd:boolean ] ] ) ] ) ; fhir:freeToShare [ fhir:v "true"^^xsd:boolean ] ; ( fhir:component [ fhir:type [ fhir:text [ fhir:v "qualifier" ] ] ; ( fhir:classifier [ fhir:text [ fhir:v "is not a major topic" ] ] ) ] ) ] [ fhir:informationType [ fhir:v "classifier" ] ; fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/cited-artifact-classification-type"^^xsd:anyURI ] ; fhir:code [ fhir:v "mesh-heading" ] ; fhir:display [ fhir:v "MeSH heading" ] ] ) ; fhir:text [ fhir:v "components (if present) include qualifier codings" ] ] ; ( fhir:classifier [ ( fhir:coding [ fhir:system [ fhir:v "https://meshb.nlm.nih.gov/"^^xsd:anyURI ] ; fhir:code [ fhir:v "D005260" ] ; fhir:display [ fhir:v "Female" ] ; fhir:userSelected [ fhir:v "false"^^xsd:boolean ] ] ) ] ) ; fhir:freeToShare [ fhir:v "true"^^xsd:boolean ] ; ( fhir:component [ fhir:type [ fhir:text [ fhir:v "qualifier" ] ] ; ( fhir:classifier [ fhir:text [ fhir:v "is not a major topic" ] ] ) ] ) ] [ fhir:informationType [ fhir:v "classifier" ] ; fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/cited-artifact-classification-type"^^xsd:anyURI ] ; fhir:code [ fhir:v "mesh-heading" ] ; fhir:display [ fhir:v "MeSH heading" ] ] ) ; fhir:text [ fhir:v "components (if present) include qualifier codings" ] ] ; ( fhir:classifier [ ( fhir:coding [ fhir:system [ fhir:v "https://meshb.nlm.nih.gov/"^^xsd:anyURI ] ; fhir:code [ fhir:v "D006801" ] ; fhir:display [ fhir:v "Humans" ] ; fhir:userSelected [ fhir:v "false"^^xsd:boolean ] ] ) ] ) ; fhir:freeToShare [ fhir:v "true"^^xsd:boolean ] ; ( fhir:component [ fhir:type [ fhir:text [ fhir:v "qualifier" ] ] ; ( fhir:classifier [ fhir:text [ fhir:v "is not a major topic" ] ] ) ] ) ] [ fhir:informationType [ fhir:v "classifier" ] ; fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/cited-artifact-classification-type"^^xsd:anyURI ] ; fhir:code [ fhir:v "mesh-heading" ] ; fhir:display [ fhir:v "MeSH heading" ] ] ) ; fhir:text [ fhir:v "components (if present) include qualifier codings" ] ] ; ( fhir:classifier [ ( fhir:coding [ fhir:system [ fhir:v "https://meshb.nlm.nih.gov/"^^xsd:anyURI ] ; fhir:code [ fhir:v "D007004" ] ; fhir:display [ fhir:v "Hypoglycemic Agents" ] ; fhir:userSelected [ fhir:v "false"^^xsd:boolean ] ] ) ] ) ; fhir:freeToShare [ fhir:v "true"^^xsd:boolean ] ; ( fhir:component [ fhir:type [ fhir:text [ fhir:v "qualifier" ] ] ; ( fhir:classifier [ fhir:text [ fhir:v "is not a major topic" ] ] ) ] [ fhir:type [ fhir:text [ fhir:v "qualifier" ] ] ; ( fhir:classifier [ ( fhir:coding [ fhir:system [ fhir:v "https://meshb.nlm.nih.gov/"^^xsd:anyURI ] ; fhir:code [ fhir:v "Q000009" ] ; fhir:display [ fhir:v "adverse effects" ] ] ) ] ) ; ( fhir:component [ fhir:type [ fhir:text [ fhir:v "is Major topic" ] ] ; ( fhir:classifier [ ( fhir:coding [ fhir:system [ fhir:v "https://ncithesaurus.nci.nih.gov/ncitbrowser"^^xsd:anyURI ] ; fhir:code [ fhir:v "C49487" ] ; fhir:display [ fhir:v "No" ] ] ) ] ) ] ) ] [ fhir:type [ fhir:text [ fhir:v "qualifier" ] ] ; ( fhir:classifier [ ( fhir:coding [ fhir:system [ fhir:v "https://meshb.nlm.nih.gov/"^^xsd:anyURI ] ; fhir:code [ fhir:v "Q000627" ] ; fhir:display [ fhir:v "therapeutic use" ] ] ) ] ) ; ( fhir:component [ fhir:type [ fhir:text [ fhir:v "is Major topic" ] ] ; ( fhir:classifier [ ( fhir:coding [ fhir:system [ fhir:v "https://ncithesaurus.nci.nih.gov/ncitbrowser"^^xsd:anyURI ] ; fhir:code [ fhir:v "C49488" ] ; fhir:display [ fhir:v "Yes" ] ] ) ] ) ] ) ] ) ] [ fhir:informationType [ fhir:v "classifier" ] ; fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/cited-artifact-classification-type"^^xsd:anyURI ] ; fhir:code [ fhir:v "mesh-heading" ] ; fhir:display [ fhir:v "MeSH heading" ] ] ) ; fhir:text [ fhir:v "components (if present) include qualifier codings" ] ] ; ( fhir:classifier [ ( fhir:coding [ fhir:system [ fhir:v "https://meshb.nlm.nih.gov/"^^xsd:anyURI ] ; fhir:code [ fhir:v "D007515" ] ; fhir:display [ fhir:v "Islets of Langerhans" ] ; fhir:userSelected [ fhir:v "false"^^xsd:boolean ] ] ) ] ) ; fhir:freeToShare [ fhir:v "true"^^xsd:boolean ] ; ( fhir:component [ fhir:type [ fhir:text [ fhir:v "qualifier" ] ] ; ( fhir:classifier [ fhir:text [ fhir:v "is not a major topic" ] ] ) ] [ fhir:type [ fhir:text [ fhir:v "qualifier" ] ] ; ( fhir:classifier [ ( fhir:coding [ fhir:system [ fhir:v "https://meshb.nlm.nih.gov/"^^xsd:anyURI ] ; fhir:code [ fhir:v "Q000187" ] ; fhir:display [ fhir:v "drug effects" ] ] ) ] ) ; ( fhir:component [ fhir:type [ fhir:text [ fhir:v "is Major topic" ] ] ; ( fhir:classifier [ ( fhir:coding [ fhir:system [ fhir:v "https://ncithesaurus.nci.nih.gov/ncitbrowser"^^xsd:anyURI ] ; fhir:code [ fhir:v "C49487" ] ; fhir:display [ fhir:v "No" ] ] ) ] ) ] ) ] [ fhir:type [ fhir:text [ fhir:v "qualifier" ] ] ; ( fhir:classifier [ ( fhir:coding [ fhir:system [ fhir:v "https://meshb.nlm.nih.gov/"^^xsd:anyURI ] ; fhir:code [ fhir:v "Q000503" ] ; fhir:display [ fhir:v "physiopathology" ] ] ) ] ) ; ( fhir:component [ fhir:type [ fhir:text [ fhir:v "is Major topic" ] ] ; ( fhir:classifier [ ( fhir:coding [ fhir:system [ fhir:v "https://ncithesaurus.nci.nih.gov/ncitbrowser"^^xsd:anyURI ] ; fhir:code [ fhir:v "C49487" ] ; fhir:display [ fhir:v "No" ] ] ) ] ) ] ) ] ) ] [ fhir:informationType [ fhir:v "classifier" ] ; fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/cited-artifact-classification-type"^^xsd:anyURI ] ; fhir:code [ fhir:v "mesh-heading" ] ; fhir:display [ fhir:v "MeSH heading" ] ] ) ; fhir:text [ fhir:v "components (if present) include qualifier codings" ] ] ; ( fhir:classifier [ ( fhir:coding [ fhir:system [ fhir:v "https://meshb.nlm.nih.gov/"^^xsd:anyURI ] ; fhir:code [ fhir:v "D008297" ] ; fhir:display [ fhir:v "Male" ] ; fhir:userSelected [ fhir:v "false"^^xsd:boolean ] ] ) ] ) ; fhir:freeToShare [ fhir:v "true"^^xsd:boolean ] ; ( fhir:component [ fhir:type [ fhir:text [ fhir:v "qualifier" ] ] ; ( fhir:classifier [ fhir:text [ fhir:v "is not a major topic" ] ] ) ] ) ] [ fhir:informationType [ fhir:v "classifier" ] ; fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/cited-artifact-classification-type"^^xsd:anyURI ] ; fhir:code [ fhir:v "mesh-heading" ] ; fhir:display [ fhir:v "MeSH heading" ] ] ) ; fhir:text [ fhir:v "components (if present) include qualifier codings" ] ] ; ( fhir:classifier [ ( fhir:coding [ fhir:system [ fhir:v "https://meshb.nlm.nih.gov/"^^xsd:anyURI ] ; fhir:code [ fhir:v "D008875" ] ; fhir:display [ fhir:v "Middle Aged" ] ; fhir:userSelected [ fhir:v "false"^^xsd:boolean ] ] ) ] ) ; fhir:freeToShare [ fhir:v "true"^^xsd:boolean ] ; ( fhir:component [ fhir:type [ fhir:text [ fhir:v "qualifier" ] ] ; ( fhir:classifier [ fhir:text [ fhir:v "is not a major topic" ] ] ) ] ) ] [ fhir:informationType [ fhir:v "classifier" ] ; fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/cited-artifact-classification-type"^^xsd:anyURI ] ; fhir:code [ fhir:v "mesh-heading" ] ; fhir:display [ fhir:v "MeSH heading" ] ] ) ; fhir:text [ fhir:v "components (if present) include qualifier codings" ] ] ; ( fhir:classifier [ ( fhir:coding [ fhir:system [ fhir:v "https://meshb.nlm.nih.gov/"^^xsd:anyURI ] ; fhir:code [ fhir:v "D000077154" ] ; fhir:display [ fhir:v "Rosiglitazone" ] ; fhir:userSelected [ fhir:v "false"^^xsd:boolean ] ] ) ] ) ; fhir:freeToShare [ fhir:v "true"^^xsd:boolean ] ; ( fhir:component [ fhir:type [ fhir:text [ fhir:v "qualifier" ] ] ; ( fhir:classifier [ fhir:text [ fhir:v "is not a major topic" ] ] ) ] ) ] [ fhir:informationType [ fhir:v "classifier" ] ; fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/cited-artifact-classification-type"^^xsd:anyURI ] ; fhir:code [ fhir:v "mesh-heading" ] ; fhir:display [ fhir:v "MeSH heading" ] ] ) ; fhir:text [ fhir:v "components (if present) include qualifier codings" ] ] ; ( fhir:classifier [ ( fhir:coding [ fhir:system [ fhir:v "https://meshb.nlm.nih.gov/"^^xsd:anyURI ] ; fhir:code [ fhir:v "D016037" ] ; fhir:display [ fhir:v "Single-Blind Method" ] ; fhir:userSelected [ fhir:v "false"^^xsd:boolean ] ] ) ] ) ; fhir:freeToShare [ fhir:v "true"^^xsd:boolean ] ; ( fhir:component [ fhir:type [ fhir:text [ fhir:v "qualifier" ] ] ; ( fhir:classifier [ fhir:text [ fhir:v "is not a major topic" ] ] ) ] ) ] [ fhir:informationType [ fhir:v "classifier" ] ; fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/cited-artifact-classification-type"^^xsd:anyURI ] ; fhir:code [ fhir:v "mesh-heading" ] ; fhir:display [ fhir:v "MeSH heading" ] ] ) ; fhir:text [ fhir:v "components (if present) include qualifier codings" ] ] ; ( fhir:classifier [ ( fhir:coding [ fhir:system [ fhir:v "https://meshb.nlm.nih.gov/"^^xsd:anyURI ] ; fhir:code [ fhir:v "D013844" ] ; fhir:display [ fhir:v "Thiazoles" ] ; fhir:userSelected [ fhir:v "false"^^xsd:boolean ] ] ) ] ) ; fhir:freeToShare [ fhir:v "true"^^xsd:boolean ] ; ( fhir:component [ fhir:type [ fhir:text [ fhir:v "qualifier" ] ] ; ( fhir:classifier [ fhir:text [ fhir:v "is not a major topic" ] ] ) ] [ fhir:type [ fhir:text [ fhir:v "qualifier" ] ] ; ( fhir:classifier [ ( fhir:coding [ fhir:system [ fhir:v "https://meshb.nlm.nih.gov/"^^xsd:anyURI ] ; fhir:code [ fhir:v "Q000009" ] ; fhir:display [ fhir:v "adverse effects" ] ] ) ] ) ; ( fhir:component [ fhir:type [ fhir:text [ fhir:v "is Major topic" ] ] ; ( fhir:classifier [ ( fhir:coding [ fhir:system [ fhir:v "https://ncithesaurus.nci.nih.gov/ncitbrowser"^^xsd:anyURI ] ; fhir:code [ fhir:v "C49487" ] ; fhir:display [ fhir:v "No" ] ] ) ] ) ] ) ] [ fhir:type [ fhir:text [ fhir:v "qualifier" ] ] ; ( fhir:classifier [ ( fhir:coding [ fhir:system [ fhir:v "https://meshb.nlm.nih.gov/"^^xsd:anyURI ] ; fhir:code [ fhir:v "Q000627" ] ; fhir:display [ fhir:v "therapeutic use" ] ] ) ] ) ; ( fhir:component [ fhir:type [ fhir:text [ fhir:v "is Major topic" ] ] ; ( fhir:classifier [ ( fhir:coding [ fhir:system [ fhir:v "https://ncithesaurus.nci.nih.gov/ncitbrowser"^^xsd:anyURI ] ; fhir:code [ fhir:v "C49488" ] ; fhir:display [ fhir:v "Yes" ] ] ) ] ) ] ) ] ) ] [ fhir:informationType [ fhir:v "classifier" ] ; fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/cited-artifact-classification-type"^^xsd:anyURI ] ; fhir:code [ fhir:v "mesh-heading" ] ; fhir:display [ fhir:v "MeSH heading" ] ] ) ; fhir:text [ fhir:v "components (if present) include qualifier codings" ] ] ; ( fhir:classifier [ ( fhir:coding [ fhir:system [ fhir:v "https://meshb.nlm.nih.gov/"^^xsd:anyURI ] ; fhir:code [ fhir:v "D045162" ] ; fhir:display [ fhir:v "Thiazolidinediones" ] ; fhir:userSelected [ fhir:v "false"^^xsd:boolean ] ] ) ] ) ; fhir:freeToShare [ fhir:v "true"^^xsd:boolean ] ; ( fhir:component [ fhir:type [ fhir:text [ fhir:v "qualifier" ] ] ; ( fhir:classifier [ fhir:text [ fhir:v "is Major topic" ] ] ) ] ) ] ) ] ) ; # fhir:url [ fhir:v "https://fevir.net/resources/Citation/267246"^^xsd:anyURI] ; # fhir:identifier ( [ fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/v2-0203"^^xsd:anyURI ] ; fhir:code [ fhir:v "ACSN" ] ; fhir:display [ fhir:v "Accession ID" ] ] ) ; fhir:text [ fhir:v "FEvIR Object Identifier" ] ] ; fhir:system [ fhir:v "https://fevir.net"^^xsd:anyURI ] ; fhir:value [ fhir:v "267246" ] ; fhir:assigner [ fhir:display [ fhir:v "Computable Publishing LLC" ] ] ] [ fhir:system [ fhir:v "https://pubmed.ncbi.nlm.nih.gov"^^xsd:anyURI ] ; fhir:value [ fhir:v "11232013" ] ] [ fhir:system [ fhir:v "urn:ietf:rfc:3986"^^xsd:anyURI ] ; fhir:value [ fhir:v "urn:oid:2.16.840.1.113883.4.642.40.44.15.44" ] ] ) ; # fhir:version [ fhir:v "2.0.0-ballot"] ; # fhir:title [ fhir:v "11232013 Rosiglitazone monotherapy is effective in patients with type 2 diabetes."] ; # fhir:status [ fhir:v "active"] ; # fhir:date [ fhir:v "2024-11-21T14:09:14+00:00"^^xsd:dateTime] ; # fhir:publisher [ fhir:v "HL7 International / Clinical Decision Support"] ; # fhir:contact ( [ fhir:name [ fhir:v "HL7 International / Clinical Decision Support" ] ; ( fhir:telecom [ fhir:system [ fhir:v "url" ] ; fhir:value [ fhir:v "http://www.hl7.org/Special/committees/dss" ] ] ) ] ) ; # fhir:description [ fhir:v "This Citation Resource is referenced in an example for the EBMonFHIR Implementation Guide."] ; # fhir:useContext ( [ fhir:code [ fhir:system [ fhir:v "http://hl7.org/fhir/citation-classification-type"^^xsd:anyURI ] ; fhir:code [ fhir:v "fevir-platform-use" ] ; fhir:display [ fhir:v "FEvIR Platform Use" ] ] ; fhir:value [ a fhir:CodeableConcept ; ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/citation-artifact-classifier"^^xsd:anyURI ] ; fhir:code [ fhir:v "medline-base" ] ; fhir:display [ fhir:v "Medline Base" ] ; fhir:userSelected [ fhir:v "false"^^xsd:boolean ] ] ) ] ] ) ; # fhir:jurisdiction ( [ ( fhir:coding [ fhir:system [ fhir:v "http://unstats.un.org/unsd/methods/m49/m49.htm"^^xsd:anyURI ] ; fhir:code [ fhir:v "001" ] ; fhir:display [ fhir:v "World" ] ] ) ] ) ; # fhir:copyright [ fhir:v "https://creativecommons.org/licenses/by-nc-sa/4.0/"] ; # fhir:approvalDate [ fhir:v "2001-04-12"^^xsd:date] ; # fhir:lastReviewDate [ fhir:v "2018-11-30"^^xsd:date] ; # fhir:author ( [ fhir:name [ fhir:v "Computable Publishing®: MEDLINE-to-FEvIR Converter" ] ] ) ; # fhir:classification ( [ fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/citation-classification-type"^^xsd:anyURI ] ; fhir:code [ fhir:v "citation-source" ] ; fhir:display [ fhir:v "Citation Source" ] ] ) ] ; ( fhir:classifier [ fhir:text [ fhir:v "MEDLINE" ] ] ) ] [ fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/citation-classification-type"^^xsd:anyURI ] ; fhir:code [ fhir:v "medline-owner" ] ; fhir:display [ fhir:v "MEDLINE Citation Owner" ] ] ) ] ; ( fhir:classifier [ ( fhir:coding [ fhir:system [ fhir:v "https://www.nlm.nih.gov/bsd/licensee/elements_descriptions.html#owner_value"^^xsd:anyURI ] ; fhir:code [ fhir:v "NLM" ] ; fhir:display [ fhir:v "National Library of Medicine, Index Section" ] ; fhir:userSelected [ fhir:v "false"^^xsd:boolean ] ] ) ] ) ] ) ; # fhir:currentState ( [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/citation-status-type"^^xsd:anyURI ] ; fhir:code [ fhir:v "medline-medline" ] ; fhir:display [ fhir:v "Medline Citation Status of Medline" ] ] ) ] [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/citation-status-type"^^xsd:anyURI ] ; fhir:code [ fhir:v "pubmed-publication-status-ppublish" ] ; fhir:display [ fhir:v "PubMed PublicationStatus of ppublish" ] ] ) ] ) ; # fhir:statusDate ( [ fhir:activity [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/citation-status-type"^^xsd:anyURI ] ; fhir:code [ fhir:v "pubmed-pubstatus-pubmed" ] ; fhir:display [ fhir:v "PubMed Pubstatus of Pubmed" ] ] ) ] ; fhir:period [ fhir:end [ fhir:v "2001-03-07T10:00:00.000Z"^^xsd:dateTime ] ] ] [ fhir:activity [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/citation-status-type"^^xsd:anyURI ] ; fhir:code [ fhir:v "pubmed-pubstatus-medline" ] ; fhir:display [ fhir:v "PubMed Pubstatus of Medline" ] ] ) ] ; fhir:period [ fhir:end [ fhir:v "2001-04-17T10:01:00.000Z"^^xsd:dateTime ] ] ] [ fhir:activity [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/citation-status-type"^^xsd:anyURI ] ; fhir:code [ fhir:v "pubmed-pubstatus-entrez" ] ; fhir:display [ fhir:v "PubMed Pubstatus of Entrez" ] ] ) ] ; fhir:period [ fhir:end [ fhir:v "2001-03-07T10:00:00.000Z"^^xsd:dateTime ] ] ] ) ; # fhir:citedArtifact [ ( fhir:identifier [ fhir:system [ fhir:v "https://pubmed.ncbi.nlm.nih.gov"^^xsd:anyURI ] ; fhir:value [ fhir:v "11232013" ] ] [ fhir:system [ fhir:v "https://doi.org"^^xsd:anyURI ] ; fhir:value [ fhir:v "10.1210/jcem.86.1.7157" ] ] ) ; ( fhir:title [ ( fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/title-type"^^xsd:anyURI ] ; fhir:code [ fhir:v "primary" ] ; fhir:display [ fhir:v "Primary title" ] ] ) ] ) ; fhir:language [ ( fhir:coding [ fhir:system [ fhir:v "urn:ietf:bcp:47"^^xsd:anyURI ] ; fhir:code [ fhir:v "en" ] ; fhir:display [ fhir:v "English" ] ] ) ] ; fhir:text [ fhir:v "Rosiglitazone monotherapy is effective in patients with type 2 diabetes." ] ] ) ; ( fhir:abstract [ fhir:text [ fhir:v "This study evaluated the efficacy and safety of rosiglitazone monotherapy in patients with type 2 diabetes. After a 4-week placebo run-in period, 493 patients with type 2 diabetes were randomized to receive rosiglitazone [2 or 4 mg twice daily (bd)] or placebo for 26 weeks. The primary end point was change in hemoglobin A(1c); other variables assessed included fasting plasma glucose, fructosamine, endogenous insulin secretion, urinary albumin excretion, serum lipids, and adverse events. Rosiglitazone (2 and 4 mg bd) decreased mean hemoglobin A(1c) relative to placebo by 1.2 and 1.5 percentage points, respectively, and reduced fasting plasma glucose concentrations relative to placebo by 3.22 and 4.22 mmol/L, respectively. Fasting plasma insulin and insulin precursor molecules decreased significantly. Homeostasis model assessment estimates indicate that rosiglitazone (2 and 4 mg bd) reduced insulin resistance by 16.0% and 24.6%, respectively, and improved ss-cell function over baseline by 49.5% and 60.0%, respectively. Urinary albumin excretion decreased significantly in the rosiglitazone (4 mg bd) group. There was no increase in adverse events with rosiglitazone. In the short-term, rosiglitazone is an insulin sensitizer that is effective and safe as monotherapy in patients with type 2 diabetes who are inadequately controlled by lifestyle interventions." ] ] ) ; ( fhir:relatesTo [ fhir:type [ fhir:v "correction-in" ] ; ( fhir:classifier [ ( fhir:coding [ fhir:system [ fhir:v "https://meshb.nlm.nih.gov/"^^xsd:anyURI ] ; fhir:code [ fhir:v "D016425" ] ; fhir:display [ fhir:v "Published Erratum" ] ; fhir:userSelected [ fhir:v "false"^^xsd:boolean ] ] ) ] ) ; fhir:citation [ fhir:v "J Clin Endocrinol Metab 2001 Apr;86(4):1659" ] ] [ fhir:type [ fhir:v "correction-in" ] ; ( fhir:classifier [ ( fhir:coding [ fhir:system [ fhir:v "https://meshb.nlm.nih.gov/"^^xsd:anyURI ] ; fhir:code [ fhir:v "D016425" ] ; fhir:display [ fhir:v "Published Erratum" ] ; fhir:userSelected [ fhir:v "false"^^xsd:boolean ] ] ) ] ) ; fhir:citation [ fhir:v "J Clin Endocrinol Metab. 2002 Feb;2(1):iv." ] ] ) ; ( fhir:publicationForm [ fhir:publishedIn [ fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/published-in-type"^^xsd:anyURI ] ; fhir:code [ fhir:v "D020492" ] ; fhir:display [ fhir:v "Periodical" ] ] ) ] ; ( fhir:identifier [ fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "https://www.nlm.nih.gov/bsd/licensee/elements_descriptions.html#issn"^^xsd:anyURI ] ; fhir:code [ fhir:v "Print" ] ; fhir:display [ fhir:v "Print" ] ] ) ; fhir:text [ fhir:v "Print ISSN Type" ] ] ; fhir:system [ fhir:v "https://portal.issn.org"^^xsd:anyURI ] ; fhir:value [ fhir:v "0021-972X" ] ] [ fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/v2-0203"^^xsd:anyURI ] ; fhir:code [ fhir:v "XX" ] ; fhir:display [ fhir:v "Organization identifier" ] ] ) ; fhir:text [ fhir:v "ISOAbbreviation" ] ] ; fhir:system [ fhir:v "https://www.issn.org/services/online-services/access-to-the-ltwa/"^^xsd:anyURI ] ; fhir:value [ fhir:v "J Clin Endocrinol Metab" ] ] [ fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/v2-0203"^^xsd:anyURI ] ; fhir:code [ fhir:v "XX" ] ; fhir:display [ fhir:v "Organization identifier" ] ] ) ; fhir:text [ fhir:v "ISSN Linking" ] ] ; fhir:system [ fhir:v "https://www.issn.org/understanding-the-issn/assignment-rules/the-issn-l-for-publications-on-multiple-media/"^^xsd:anyURI ] ; fhir:value [ fhir:v "0021-972X" ] ] [ fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/v2-0203"^^xsd:anyURI ] ; fhir:code [ fhir:v "XX" ] ; fhir:display [ fhir:v "Organization identifier" ] ] ) ; fhir:text [ fhir:v "Medline Title Abbreviation" ] ] ; fhir:system [ fhir:v "https://www.nlm.nih.gov/tsd/cataloging/contructitleabbre.html"^^xsd:anyURI ] ; fhir:value [ fhir:v "J Clin Endocrinol Metab" ] ] [ fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/v2-0203"^^xsd:anyURI ] ; fhir:code [ fhir:v "XX" ] ; fhir:display [ fhir:v "Organization identifier" ] ] ) ; fhir:text [ fhir:v "NLM Unique ID" ] ] ; fhir:system [ fhir:v "https://locatorplus.gov/cgi-bin/Pwebrecon.cgi?DB=local"^^xsd:anyURI ] ; fhir:value [ fhir:v "0375362" ] ] ) ; fhir:title [ fhir:v "The Journal of clinical endocrinology and metabolism" ] ; fhir:publisherLocation [ fhir:v "United States" ] ] ; fhir:citedMedium [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/cited-medium"^^xsd:anyURI ] ; fhir:code [ fhir:v "print" ] ; fhir:display [ fhir:v "Print" ] ] ) ] ; fhir:volume [ fhir:v "86" ] ; fhir:issue [ fhir:v "1" ] ; fhir:articleDate [ fhir:v "2001-01"^^xsd:gYearMonth ] ; fhir:publicationDateText [ fhir:v "2001-Jan" ] ; ( fhir:language [ ( fhir:coding [ fhir:system [ fhir:v "urn:ietf:bcp:47"^^xsd:anyURI ] ; fhir:code [ fhir:v "en" ] ; fhir:display [ fhir:v "English" ] ] ) ] ) ; fhir:pageString [ fhir:v "280-8" ] ] ) ; ( fhir:webLocation [ ( fhir:classifier [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/artifact-url-classifier"^^xsd:anyURI ] ; fhir:code [ fhir:v "abstract" ] ; fhir:display [ fhir:v "Abstract" ] ] ) ] ) ; fhir:url [ fhir:v "https://pubmed.ncbi.nlm.nih.gov/11232013/"^^xsd:anyURI ] ] ) ; ( fhir:classification [ fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/cited-artifact-classification-type"^^xsd:anyURI ] ; fhir:code [ fhir:v "publishing-model" ] ; fhir:display [ fhir:v "Publishing Model" ] ; fhir:userSelected [ fhir:v "false"^^xsd:boolean ] ] ) ] ; ( fhir:classifier [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/citation-artifact-classifier"^^xsd:anyURI ] ; fhir:code [ fhir:v "Print" ] ; fhir:display [ fhir:v "Print" ] ; fhir:userSelected [ fhir:v "false"^^xsd:boolean ] ] ) ] ) ] [ fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/cited-artifact-classification-type"^^xsd:anyURI ] ; fhir:code [ fhir:v "chemical" ] ; fhir:display [ fhir:v "Chemical" ] ; fhir:userSelected [ fhir:v "false"^^xsd:boolean ] ] ) ] ; ( fhir:classifier [ ( fhir:coding [ fhir:system [ fhir:v "https://meshb.nlm.nih.gov/"^^xsd:anyURI ] ; fhir:code [ fhir:v "D001786" ] ; fhir:display [ fhir:v "Blood Glucose" ] ; fhir:userSelected [ fhir:v "false"^^xsd:boolean ] ] ) ] [ ( fhir:coding [ fhir:system [ fhir:v "https://meshb.nlm.nih.gov/"^^xsd:anyURI ] ; fhir:code [ fhir:v "D007004" ] ; fhir:display [ fhir:v "Hypoglycemic Agents" ] ; fhir:userSelected [ fhir:v "false"^^xsd:boolean ] ] ) ] [ ( fhir:coding [ fhir:system [ fhir:v "https://meshb.nlm.nih.gov/"^^xsd:anyURI ] ; fhir:code [ fhir:v "D013844" ] ; fhir:display [ fhir:v "Thiazoles" ] ; fhir:userSelected [ fhir:v "false"^^xsd:boolean ] ] ) ] [ ( fhir:coding [ fhir:system [ fhir:v "https://meshb.nlm.nih.gov/"^^xsd:anyURI ] ; fhir:code [ fhir:v "D045162" ] ; fhir:display [ fhir:v "Thiazolidinediones" ] ; fhir:userSelected [ fhir:v "false"^^xsd:boolean ] ] ) ] [ ( fhir:coding [ fhir:system [ fhir:v "https://www.cas.org/support/documentation/chemical-substances"^^xsd:anyURI ] ; fhir:code [ fhir:v "05V02F2KDG" ] ; fhir:userSelected [ fhir:v "false"^^xsd:boolean ] ] [ fhir:system [ fhir:v "https://meshb.nlm.nih.gov/"^^xsd:anyURI ] ; fhir:code [ fhir:v "D000077154" ] ; fhir:display [ fhir:v "Rosiglitazone" ] ; fhir:userSelected [ fhir:v "false"^^xsd:boolean ] ] ) ] ) ] [ fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/cited-artifact-classification-type"^^xsd:anyURI ] ; fhir:code [ fhir:v "mesh-heading" ] ; fhir:display [ fhir:v "MeSH heading" ] ] ) ] ; ( fhir:artifactAssessment [ fhir:reference [ fhir:v "#meshHeading0" ] ; fhir:type [ fhir:v "ArtifactAssessment"^^xsd:anyURI ] ] ) ] [ fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/cited-artifact-classification-type"^^xsd:anyURI ] ; fhir:code [ fhir:v "publication-type" ] ; fhir:display [ fhir:v "Publication type" ] ] ) ] ; ( fhir:classifier [ ( fhir:coding [ fhir:system [ fhir:v "https://meshb.nlm.nih.gov/"^^xsd:anyURI ] ; fhir:code [ fhir:v "D016430" ] ; fhir:display [ fhir:v "Clinical Trial" ] ; fhir:userSelected [ fhir:v "false"^^xsd:boolean ] ] ) ] [ ( fhir:coding [ fhir:system [ fhir:v "https://meshb.nlm.nih.gov/"^^xsd:anyURI ] ; fhir:code [ fhir:v "D016428" ] ; fhir:display [ fhir:v "Journal Article" ] ; fhir:userSelected [ fhir:v "false"^^xsd:boolean ] ] ) ] [ ( fhir:coding [ fhir:system [ fhir:v "https://meshb.nlm.nih.gov/"^^xsd:anyURI ] ; fhir:code [ fhir:v "D016448" ] ; fhir:display [ fhir:v "Multicenter Study" ] ; fhir:userSelected [ fhir:v "false"^^xsd:boolean ] ] ) ] [ ( fhir:coding [ fhir:system [ fhir:v "https://meshb.nlm.nih.gov/"^^xsd:anyURI ] ; fhir:code [ fhir:v "D016449" ] ; fhir:display [ fhir:v "Randomized Controlled Trial" ] ; fhir:userSelected [ fhir:v "false"^^xsd:boolean ] ] ) ] ) ] [ fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/cited-artifact-classification-type"^^xsd:anyURI ] ; fhir:code [ fhir:v "knowledge-artifact-type" ] ; fhir:display [ fhir:v "Knowledge Artifact Type" ] ; fhir:userSelected [ fhir:v "false"^^xsd:boolean ] ] ) ] ; ( fhir:classifier [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/citation-artifact-classifier"^^xsd:anyURI ] ; fhir:code [ fhir:v "D016428" ] ; fhir:display [ fhir:v "Journal Article" ] ; fhir:userSelected [ fhir:v "false"^^xsd:boolean ] ] ) ] ) ; ( fhir:artifactAssessment [ fhir:display [ fhir:v "Classifier added by Computable Publishing LLC" ] ] ) ] [ fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/cited-artifact-classification-type"^^xsd:anyURI ] ; fhir:code [ fhir:v "citation-subset" ] ; fhir:display [ fhir:v "Citation subset" ] ; fhir:userSelected [ fhir:v "false"^^xsd:boolean ] ] ) ] ; ( fhir:classifier [ ( fhir:coding [ fhir:system [ fhir:v "https://www.nlm.nih.gov/bsd/licensee/elements_descriptions.html#citationsubset"^^xsd:anyURI ] ; fhir:code [ fhir:v "IM" ] ; fhir:display [ fhir:v "IM" ] ; fhir:userSelected [ fhir:v "false"^^xsd:boolean ] ] ) ] ) ] ) ; fhir:contributorship [ fhir:complete [ fhir:v "true"^^xsd:boolean ] ; ( fhir:entry [ fhir:contributor [ fhir:reference [ fhir:v "#contributor0" ] ; fhir:type [ fhir:v "Practitioner"^^xsd:anyURI ] ; fhir:display [ fhir:v "Lebovitz HE" ] ] ; fhir:forenameInitials [ fhir:v "HE" ] ; ( fhir:affiliation [ fhir:display [ fhir:v "Department of Medicine, State University of New York, Brooklyn, New York 11203, USA. hlebovitz@attglobal.net" ] ] ) ] [ fhir:contributor [ fhir:reference [ fhir:v "#contributor1" ] ; fhir:type [ fhir:v "Practitioner"^^xsd:anyURI ] ; fhir:display [ fhir:v "Dole JF" ] ] ; fhir:forenameInitials [ fhir:v "JF" ] ] [ fhir:contributor [ fhir:reference [ fhir:v "#contributor2" ] ; fhir:type [ fhir:v "Practitioner"^^xsd:anyURI ] ; fhir:display [ fhir:v "Patwardhan R" ] ] ; fhir:forenameInitials [ fhir:v "R" ] ] [ fhir:contributor [ fhir:reference [ fhir:v "#contributor3" ] ; fhir:type [ fhir:v "Practitioner"^^xsd:anyURI ] ; fhir:display [ fhir:v "Rappaport EB" ] ] ; fhir:forenameInitials [ fhir:v "EB" ] ] [ fhir:contributor [ fhir:reference [ fhir:v "#contributor4" ] ; fhir:type [ fhir:v "Practitioner"^^xsd:anyURI ] ; fhir:display [ fhir:v "Freed MI" ] ] ; fhir:forenameInitials [ fhir:v "MI" ] ] [ fhir:contributor [ fhir:reference [ fhir:v "#contributor5" ] ; fhir:type [ fhir:v "Organization"^^xsd:anyURI ] ; fhir:display [ fhir:v "Rosiglitazone Clinical Trials Study Group" ] ] ] ) ] ] . #
IG © 2024+ HL7 International / Clinical Decision Support. Package hl7.fhir.uv.ebm#2.0.0-ballot based on FHIR 6.0.0-ballot2. Generated 2024-11-21
Links: Table of Contents |
QA Report
| Version History |
|
Propose a change