Levothroxine-Monitoring-Titration-Activities
type: PlanDefinition
node role: treeRoot
id:
  v: Levothroxine-Monitoring-Titration-Activities
meta:
  version id:
    v: 0
  last updated:
    v: 2026-03-11T16:01:52Z
language:
  v: en
text:
  status:
    v: extensions
  div:
    v: Id: Levothroxine-Monitoring-Titration-Activities Url: Levothroxine-Monitoring-Titration-Activities Version: 2.0.0-ballot c4ef9bcf-718f-421a-984e-45dae567935e urn:oid:2.16.840.1.113883.4.642.40.64.34.9 Title: Levothroxine-Monitoring-Titration-Activities Type: code: clinical-protocol Date: 2026-03-24 21:36:22+0000 Publisher: HL7 International / Biomedical Research and Regulation Description: Levothroxine-Monitoring Jurisdiction: 001 Actions: AS: Activity Start Then: : Blood Sample: Blood Sample Then: : TSH Measurement: TSH Measurement Then: : Clinical Review: Clinical Review Then: : If: Start: ({’TSH’: 0.4 ‘mU/L’, operation = ‘<‘}) : If: Start: ({’TSH’: 0.4 ‘mU/L’, operation = ‘>=’} | {’TSH’: 4.6 ‘mU/L, operation = ‘<=’}) : If: Start: ({’TSH’: 4.6 ‘mU/L’, operation = ‘>’}) MedicationRequest: MedicationRequest Then: : AF: Activity Finish Then: Definition: http://example.org/ActivityDefinition/ActivityFinish Increase Dose: Increase Dose Then: : No Dose Change: No Dose Change Then: : Decrease Dose: Decrease Dose Then: :
url:
  v: http://hl7.org/fhir/uv/vulcan-schedule/PlanDefinition/Levothroxine-Monitoring-Titration-Activities
  l: Levothroxine-Monitoring-Titration-Activities
identifier:
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    l: plandefinition
identifier:
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    v: urn:ietf:rfc:3986
    l: 3986
  value:
    v: urn:oid:2.16.840.1.113883.4.642.40.64.34.9
version:
  v: 2.0.0-ballot
name:
  v: Levothroxine-Monitoring-Titration-Activities
title:
  v: Levothroxine-Monitoring-Titration-Activities
type:
  coding:
    code:
      v: clinical-protocol
status:
  v: active
date:
  v: 2026-03-24T21:36:22+00:00
publisher:
  v: HL7 International / Biomedical Research and Regulation
contact:
  name:
    v: HL7 International / Biomedical Research and Regulation
  telecom:
    system:
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    value:
      v: http://www.hl7.org/Special/committees/rcrim
  telecom:
    system:
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description:
  v: Levothroxine-Monitoring
jurisdiction:
  coding:
    system:
      v: http://unstats.un.org/unsd/methods/m49/m49.htm
      l: m49.htm
    code:
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    display:
      v: World
action:
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        v: AS
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        v: AS
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      l: soaTimepoint
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  description:
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  grouping behavior:
    v: visual-group
  selection behavior:
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  definition: Canonical
    v: http://example.org/ActivityDefinition/start
    l: start
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      extension:
        value: String
      extension:
        value: Duration
      extension:
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      extension:
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        v: AS
    url:
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  title:
    v: Blood Sample
  description:
    v: Blood Sample
  grouping behavior:
    v: visual-group
  selection behavior:
    v: exactly-one
  definition: Canonical

v: 0

v: s

v: 30

v: min

value:
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system:
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code:
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value:
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code:
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v: soaTargetId
l: soaTargetId

v: soaTransitionType
l: soaTransitionType

String
v: FS

v: soaTransitionDelay
l: soaTransitionDelay

Duration
value:
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system:
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code:
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v: soaTransitionRange
l: soaTransitionRange

Range
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v: soaTargetName
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String
v: Blood Sample

v: 0

v: s

v: 30

v: min

value:
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code:
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value:
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code:
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extension:
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    value: String
      v: FS
  extension:
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    value: Duration
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      system:
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      v: TSH Measurement
  url:
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    l: soaTransition

v: 0

v: s

v: 0

v: s

extension:
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    value: Quantity
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        l: unitsofmeasure.org
      code:
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      v: soaReferenceTimePoint
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    value: String
      v: AS
  extension:
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      v: false
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      l: soaPlannedDuration
    value: Duration
      value:
        v: 30
      system:
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        l: unitsofmeasure.org
      code:
        v: min
  extension:
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      v: Activity
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      v: A
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      v: AS
  url:
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    l: soaTimepoint
title:
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description:
  v: TSH Measurement
grouping behavior:
  v: visual-group
selection behavior:
  v: exactly-one
definition: Canonical
  v: http://example.org/ActivityDefinition/TSHMeasurement
  l: TSHMeasurement
action:
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    extension:
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      value: Range
    extension:
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        v: soaTargetName
        l: soaTargetName
      value: String
        v: Clinical Review
    url:
      v: http://hl7.org/fhir/uv/vulcan-schedule/StructureDefinition/soaTransition
      l: soaTransition

v: 0

v: s

v: 0

v: s

v: 0

v: s

value:
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system:
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  l: unitsofmeasure.org
code:
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value:
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system:
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  l: unitsofmeasure.org
code:
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extension:
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      l: soaPlannedTimePoint
    value: Quantity
      value:
        v: 0
      system:
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        l: unitsofmeasure.org
      code:
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  extension:
    url:
      v: soaReferenceTimePoint
      l: soaReferenceTimePoint
    value: String
      v: AS
  extension:
    url:
      v: soaRepeatAllowed
      l: soaRepeatAllowed
    value: Boolean
      v: false
  extension:
    url:
      v: soaPlannedDuration
      l: soaPlannedDuration
    value: Duration
      value:
        v: 30
      system:
        v: http://unitsofmeasure.org
        l: unitsofmeasure.org
      code:
        v: min
  extension:
    url:
      v: soaTimePointType
      l: soaTimePointType
    value: String
      v: Activity
  extension:
    url:
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      l: soaTimePointSubType
    value: String
      v: A
  extension:
    url:
      v: soaPlannedRange
      l: soaPlannedRange
    value: Range
  extension:
    url:
      v: soaRangeFromTimePoint
      l: soaRangeFromTimePoint
    value: String
      v: AS
  url:
    v: http://hl7.org/fhir/uv/vulcan-schedule/StructureDefinition/soaTimepoint
    l: soaTimepoint
title:
  v: Clinical Review
description:
  v: Clinical Review
grouping behavior:
  v: visual-group
selection behavior:
  v: exactly-one
definition: Canonical
  v: http://example.org/ActivityDefinition/ClinicalReview
  l: ClinicalReview
action:
  extension:
    extension:
      url:
        v: soaTargetId
        l: soaTargetId
      value: String
    extension:
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      value: String
        v: FS
    extension:
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      value: Duration
    extension:
      url:
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        l: soaTransitionRange
      value: Range
    extension:
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        v: soaTargetName
        l: soaTargetName
      value: String
        v: Increase Dose
    url:
      v: http://hl7.org/fhir/uv/vulcan-schedule/StructureDefinition/soaTransition
      l: soaTransition
  condition:
    kind:
      v: start
    expression:
      language:
        v: text/x-soa-expressionplain
      expression:
        v: {’TSH’: 0.4 ‘mU/L’, operation = ‘<‘}
action:
  extension:
    extension:
      url:
        v: soaTargetId
        l: soaTargetId
      value: String
    extension:
      url:
        v: soaTransitionType
        l: soaTransitionType
      value: String
        v: FS
    extension:
      url:
        v: soaTransitionDelay
        l: soaTransitionDelay
      value: Duration
    extension:
      url:
        v: soaTransitionRange
        l: soaTransitionRange
      value: Range
    extension:
      url:
        v: soaTargetName
        l: soaTargetName
      value: String
        v: No Dose Change
    url:
      v: http://hl7.org/fhir/uv/vulcan-schedule/StructureDefinition/soaTransition
      l: soaTransition
  condition:
    kind:
      v: start
    expression:
      language:
        v: text/x-soa-expressionplain
      expression:
        v: {’TSH’: 0.4 ‘mU/L’, operation = ‘>=’} | {’TSH’: 4.6 ‘mU/L, operation = ‘<=’}
action:
  extension:
    extension:
      url:
        v: soaTargetId
        l: soaTargetId
      value: String
    extension:
      url:
        v: soaTransitionType
        l: soaTransitionType
      value: String
        v: FS
    extension:
      url:
        v: soaTransitionDelay
        l: soaTransitionDelay
      value: Duration
    extension:
      url:
        v: soaTransitionRange
        l: soaTransitionRange
      value: Range
    extension:
      url:
        v: soaTargetName
        l: soaTargetName
      value: String
        v: Decrease Dose
    url:
      v: http://hl7.org/fhir/uv/vulcan-schedule/StructureDefinition/soaTransition
      l: soaTransition
  condition:
    kind:
      v: start
    expression:
      language:
        v: text/x-soa-expressionplain
      expression:
        v: {’TSH’: 4.6 ‘mU/L’, operation = ‘>’}

v: 0

v: s

v: 0

v: s

v: 0

v: s

value:
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system:
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  l: unitsofmeasure.org
code:
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value:
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system:
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code:
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v: 0

v: s

value:
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value:
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code:
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v: 0

v: s

value:
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system:
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code:
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value:
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system:
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  l: unitsofmeasure.org
code:
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extension:
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    value: Quantity
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        l: unitsofmeasure.org
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  extension:
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      l: soaReferenceTimePoint
    value: String
      v: AS
  extension:
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      l: soaRepeatAllowed
    value: Boolean
      v: false
  extension:
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    value: Duration
      value:
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      system:
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        l: unitsofmeasure.org
      code:
        v: min
  extension:
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      v: Activity
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      v: A
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    value: Range
  extension:
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    value: String
      v: AS
  url:
    v: http://hl7.org/fhir/uv/vulcan-schedule/StructureDefinition/soaTimepoint
    l: soaTimepoint
title:
  v: MedicationRequest
description:
  v: MedicationRequest
grouping behavior:
  v: visual-group
selection behavior:
  v: exactly-one
definition: Canonical
  v: http://example.org/ActivityDefinition/MedicationRequest
  l: MedicationRequest
action:
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      url:
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        l: soaTargetId
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    extension:
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        v: FS
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        l: soaTransitionDelay
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    extension:
      url:
        v: soaTransitionRange
        l: soaTransitionRange
      value: Range
    extension:
      url:
        v: soaTargetName
        l: soaTargetName
      value: String
        v: AF
    url:
      v: http://hl7.org/fhir/uv/vulcan-schedule/StructureDefinition/soaTransition
      l: soaTransition

v: 0

v: s

v: 0

v: s

v: 0

v: s

value:
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system:
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  l: unitsofmeasure.org
code:
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value:
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system:
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  l: unitsofmeasure.org
code:
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extension:
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    value: Quantity
      value:
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        l: unitsofmeasure.org
      code:
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      l: soaReferenceTimePoint
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      v: AS
  extension:
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      v: false
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      system:
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        l: unitsofmeasure.org
      code:
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  extension:
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      v: Activity
  extension:
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    value: String
      v: AF
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    value: Range
  extension:
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    value: String
      v: AS
  url:
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    l: soaTimepoint
title:
  v: AF
description:
  v: Activity Finish
definition: Canonical
  v: http://example.org/ActivityDefinition/ActivityFinish
  l: ActivityFinish

v: 0

v: s

v: 0

v: s

extension:
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    url:
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      l: soaPlannedTimePoint
    value: Quantity
      value:
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      system:
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        l: unitsofmeasure.org
      code:
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    value: String
      v: AS
  extension:
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      l: soaRepeatAllowed
    value: Boolean
      v: false
  extension:
    url:
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      l: soaPlannedDuration
    value: Duration
      value:
        v: 24
      system:
        v: http://unitsofmeasure.org
        l: unitsofmeasure.org
      code:
        v: h
  extension:
    url:
      v: soaTimePointType
      l: soaTimePointType
    value: String
      v: Activity
  extension:
    url:
      v: soaTimePointSubType
      l: soaTimePointSubType
    value: String
      v: A
  extension:
    url:
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      l: soaPlannedRange
    value: Range
  extension:
    url:
      v: soaRangeFromTimePoint
      l: soaRangeFromTimePoint
    value: String
      v: AS
  url:
    v: http://hl7.org/fhir/uv/vulcan-schedule/StructureDefinition/soaTimepoint
    l: soaTimepoint
title:
  v: Increase Dose
description:
  v: Increase Dose
grouping behavior:
  v: visual-group
selection behavior:
  v: exactly-one
definition: Canonical
  v: http://example.org/ActivityDefinition/IncreaseDose
  l: IncreaseDose
action:
  extension:
    extension:
      url:
        v: soaTargetId
        l: soaTargetId
      value: String
    extension:
      url:
        v: soaTransitionType
        l: soaTransitionType
      value: String
        v: FS
    extension:
      url:
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        l: soaTransitionDelay
      value: Duration
    extension:
      url:
        v: soaTransitionRange
        l: soaTransitionRange
      value: Range
    extension:
      url:
        v: soaTargetName
        l: soaTargetName
      value: String
        v: MedicationRequest
    url:
      v: http://hl7.org/fhir/uv/vulcan-schedule/StructureDefinition/soaTransition
      l: soaTransition

v: 24

v: h

v: 24

v: h

v: 0

v: s

value:
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system:
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  l: unitsofmeasure.org
code:
  v: s

value:
  v: 0
system:
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  l: unitsofmeasure.org
code:
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extension:
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      l: soaPlannedTimePoint
    value: Quantity
      value:
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      system:
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        l: unitsofmeasure.org
      code:
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  extension:
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      l: soaReferenceTimePoint
    value: String
      v: AS
  extension:
    url:
      v: soaRepeatAllowed
      l: soaRepeatAllowed
    value: Boolean
      v: false
  extension:
    url:
      v: soaPlannedDuration
      l: soaPlannedDuration
    value: Duration
      value:
        v: 24
      system:
        v: http://unitsofmeasure.org
        l: unitsofmeasure.org
      code:
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  extension:
    url:
      v: soaTimePointType
      l: soaTimePointType
    value: String
      v: Activity
  extension:
    url:
      v: soaTimePointSubType
      l: soaTimePointSubType
    value: String
      v: A
  extension:
    url:
      v: soaPlannedRange
      l: soaPlannedRange
    value: Range
  extension:
    url:
      v: soaRangeFromTimePoint
      l: soaRangeFromTimePoint
    value: String
      v: AS
  url:
    v: http://hl7.org/fhir/uv/vulcan-schedule/StructureDefinition/soaTimepoint
    l: soaTimepoint
title:
  v: No Dose Change
description:
  v: No Dose Change
grouping behavior:
  v: visual-group
selection behavior:
  v: exactly-one
definition: Canonical
  v: http://example.org/ActivityDefinition/NoDoseChange
  l: NoDoseChange
action:
  extension:
    extension:
      url:
        v: soaTargetId
        l: soaTargetId
      value: String
    extension:
      url:
        v: soaTransitionType
        l: soaTransitionType
      value: String
        v: FS
    extension:
      url:
        v: soaTransitionDelay
        l: soaTransitionDelay
      value: Duration
    extension:
      url:
        v: soaTransitionRange
        l: soaTransitionRange
      value: Range
    extension:
      url:
        v: soaTargetName
        l: soaTargetName
      value: String
        v: MedicationRequest
    url:
      v: http://hl7.org/fhir/uv/vulcan-schedule/StructureDefinition/soaTransition
      l: soaTransition

v: 24

v: h

v: 24

v: h

v: 0

v: s

value:
  v: 0
system:
  v: http://unitsofmeasure.org
  l: unitsofmeasure.org
code:
  v: s

value:
  v: 0
system:
  v: http://unitsofmeasure.org
  l: unitsofmeasure.org
code:
  v: s

extension:
  extension:
    url:
      v: soaPlannedTimePoint
      l: soaPlannedTimePoint
    value: Quantity
      value:
        v: 0
      system:
        v: http://unitsofmeasure.org
        l: unitsofmeasure.org
      code:
        v: s
  extension:
    url:
      v: soaReferenceTimePoint
      l: soaReferenceTimePoint
    value: String
      v: AS
  extension:
    url:
      v: soaRepeatAllowed
      l: soaRepeatAllowed
    value: Boolean
      v: false
  extension:
    url:
      v: soaPlannedDuration
      l: soaPlannedDuration
    value: Duration
      value:
        v: 24
      system:
        v: http://unitsofmeasure.org
        l: unitsofmeasure.org
      code:
        v: h
  extension:
    url:
      v: soaTimePointType
      l: soaTimePointType
    value: String
      v: Activity
  extension:
    url:
      v: soaTimePointSubType
      l: soaTimePointSubType
    value: String
      v: A
  extension:
    url:
      v: soaPlannedRange
      l: soaPlannedRange
    value: Range
  extension:
    url:
      v: soaRangeFromTimePoint
      l: soaRangeFromTimePoint
    value: String
      v: AS
  url:
    v: http://hl7.org/fhir/uv/vulcan-schedule/StructureDefinition/soaTimepoint
    l: soaTimepoint
title:
  v: Decrease Dose
description:
  v: Decrease Dose
grouping behavior:
  v: visual-group
selection behavior:
  v: exactly-one
definition: Canonical
  v: http://example.org/ActivityDefinition/DecreaseDose
  l: DecreaseDose
action:
  extension:
    extension:
      url:
        v: soaTargetId
        l: soaTargetId
      value: String
    extension:
      url:
        v: soaTransitionType
        l: soaTransitionType
      value: String
        v: FS
    extension:
      url:
        v: soaTransitionDelay
        l: soaTransitionDelay
      value: Duration
    extension:
      url:
        v: soaTransitionRange
        l: soaTransitionRange
      value: Range
    extension:
      url:
        v: soaTargetName
        l: soaTargetName
      value: String
        v: MedicationRequest
    url:
      v: http://hl7.org/fhir/uv/vulcan-schedule/StructureDefinition/soaTransition
      l: soaTransition

v: 24

v: h

v: 24

v: h

v: 0

v: s

value:
  v: 0
system:
  v: http://unitsofmeasure.org
  l: unitsofmeasure.org
code:
  v: s

value:
  v: 0
system:
  v: http://unitsofmeasure.org
  l: unitsofmeasure.org
code:
  v: s