API for the Exchange of Medicinal Product Information (APIX)
0.1.0 - ci-build

API for the Exchange of Medicinal Product Information (APIX), published by Gravitate Health Project. This guide is not an authorized publication; it is the continuous build for version 0.1.0 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/APIX---API-Exchange-for-Medicinal-Products/ and changes regularly. See the Directory of published versions

: APIX CTD/eCTD Section Code System - JSON Representation

Active as of 2025-11-24

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{
  "resourceType" : "CodeSystem",
  "id" : "ctd-section",
  "text" : {
    "status" : "generated",
    "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: CodeSystem ctd-section</b></p><a name=\"ctd-section\"> </a><a name=\"hcctd-section\"> </a><p>This case-sensitive code system <code>http://hl7.org/fhir/uv/apix/CodeSystem/ctd-section</code> defines the following codes:</p><table class=\"codes\"><tr><td style=\"white-space:nowrap\"><b>Code</b></td><td><b>Display</b></td></tr><tr><td style=\"white-space:nowrap\">1.0<a name=\"ctd-section-1.460\"> </a></td><td>Cover Letter</td></tr><tr><td style=\"white-space:nowrap\">1.2<a name=\"ctd-section-1.462\"> </a></td><td>Administrative Information</td></tr><tr><td style=\"white-space:nowrap\">1.3.1<a name=\"ctd-section-1.463.461\"> </a></td><td>SPC, Labelling and Package Leaflet</td></tr><tr><td style=\"white-space:nowrap\">1.3.2<a name=\"ctd-section-1.463.462\"> </a></td><td>Mock-ups</td></tr><tr><td style=\"white-space:nowrap\">1.3.3<a name=\"ctd-section-1.463.463\"> </a></td><td>Specimens</td></tr><tr><td style=\"white-space:nowrap\">1.4<a name=\"ctd-section-1.464\"> </a></td><td>Information about the Experts</td></tr><tr><td style=\"white-space:nowrap\">1.8.1<a name=\"ctd-section-1.468.461\"> </a></td><td>Risk Management Plan</td></tr><tr><td style=\"white-space:nowrap\">1.9<a name=\"ctd-section-1.469\"> </a></td><td>Pharmacovigilance System</td></tr><tr><td style=\"white-space:nowrap\">2.2<a name=\"ctd-section-2.462\"> </a></td><td>Introduction</td></tr><tr><td style=\"white-space:nowrap\">2.3<a name=\"ctd-section-2.463\"> </a></td><td>Quality Overall Summary</td></tr><tr><td style=\"white-space:nowrap\">2.4<a name=\"ctd-section-2.464\"> </a></td><td>Nonclinical Overview</td></tr><tr><td style=\"white-space:nowrap\">2.5<a name=\"ctd-section-2.465\"> </a></td><td>Clinical Overview</td></tr><tr><td style=\"white-space:nowrap\">2.6<a name=\"ctd-section-2.466\"> </a></td><td>Nonclinical Summary</td></tr><tr><td style=\"white-space:nowrap\">2.7<a name=\"ctd-section-2.467\"> </a></td><td>Clinical Summary</td></tr><tr><td style=\"white-space:nowrap\">3.2.S.1<a name=\"ctd-section-3.462.46S.461\"> </a></td><td>General Information (Drug Substance)</td></tr><tr><td style=\"white-space:nowrap\">3.2.S.1.1<a name=\"ctd-section-3.462.46S.461.461\"> </a></td><td>Nomenclature</td></tr><tr><td style=\"white-space:nowrap\">3.2.S.1.2<a name=\"ctd-section-3.462.46S.461.462\"> </a></td><td>Structure</td></tr><tr><td style=\"white-space:nowrap\">3.2.S.1.3<a name=\"ctd-section-3.462.46S.461.463\"> </a></td><td>General Properties</td></tr><tr><td style=\"white-space:nowrap\">3.2.S.2<a name=\"ctd-section-3.462.46S.462\"> </a></td><td>Manufacture (Drug Substance)</td></tr><tr><td style=\"white-space:nowrap\">3.2.S.3<a name=\"ctd-section-3.462.46S.463\"> </a></td><td>Characterisation (Drug Substance)</td></tr><tr><td style=\"white-space:nowrap\">3.2.S.4<a name=\"ctd-section-3.462.46S.464\"> </a></td><td>Control of Drug Substance</td></tr><tr><td style=\"white-space:nowrap\">3.2.S.5<a name=\"ctd-section-3.462.46S.465\"> </a></td><td>Reference Standards or Materials</td></tr><tr><td style=\"white-space:nowrap\">3.2.S.6<a name=\"ctd-section-3.462.46S.466\"> </a></td><td>Container Closure System</td></tr><tr><td style=\"white-space:nowrap\">3.2.S.7<a name=\"ctd-section-3.462.46S.467\"> </a></td><td>Stability (Drug Substance)</td></tr><tr><td style=\"white-space:nowrap\">3.2.P.1<a name=\"ctd-section-3.462.46P.461\"> </a></td><td>Description and Composition of the Drug Product</td></tr><tr><td style=\"white-space:nowrap\">3.2.P.2<a name=\"ctd-section-3.462.46P.462\"> </a></td><td>Pharmaceutical Development</td></tr><tr><td style=\"white-space:nowrap\">3.2.P.3<a name=\"ctd-section-3.462.46P.463\"> </a></td><td>Manufacture (Drug Product)</td></tr><tr><td style=\"white-space:nowrap\">3.2.P.4<a name=\"ctd-section-3.462.46P.464\"> </a></td><td>Control of Excipients</td></tr><tr><td style=\"white-space:nowrap\">3.2.P.5<a name=\"ctd-section-3.462.46P.465\"> </a></td><td>Control of Drug Product</td></tr><tr><td style=\"white-space:nowrap\">3.2.P.5.1<a name=\"ctd-section-3.462.46P.465.461\"> </a></td><td>Specification(s)</td></tr><tr><td style=\"white-space:nowrap\">3.2.P.5.6<a name=\"ctd-section-3.462.46P.465.466\"> </a></td><td>Justification of Specification(s)</td></tr><tr><td style=\"white-space:nowrap\">3.2.P.8<a name=\"ctd-section-3.462.46P.468\"> </a></td><td>Stability (Drug Product)</td></tr><tr><td style=\"white-space:nowrap\">3.2.P.8.1<a name=\"ctd-section-3.462.46P.468.461\"> </a></td><td>Stability Summary and Conclusion</td></tr><tr><td style=\"white-space:nowrap\">3.2.P.8.2<a name=\"ctd-section-3.462.46P.468.462\"> </a></td><td>Post-approval Stability Protocol and Commitment</td></tr><tr><td style=\"white-space:nowrap\">3.2.P.8.3<a name=\"ctd-section-3.462.46P.468.463\"> </a></td><td>Stability Data</td></tr><tr><td style=\"white-space:nowrap\">3.2.A.1<a name=\"ctd-section-3.462.46A.461\"> </a></td><td>Facilities and Equipment</td></tr><tr><td style=\"white-space:nowrap\">3.2.A.2<a name=\"ctd-section-3.462.46A.462\"> </a></td><td>Adventitious Agents Safety Evaluation</td></tr><tr><td style=\"white-space:nowrap\">3.2.A.3<a name=\"ctd-section-3.462.46A.463\"> </a></td><td>Excipients</td></tr><tr><td style=\"white-space:nowrap\">3.2.R<a name=\"ctd-section-3.462.46R\"> </a></td><td>Regional Information</td></tr><tr><td style=\"white-space:nowrap\">4.1<a name=\"ctd-section-4.461\"> </a></td><td>Table of Contents (Nonclinical)</td></tr><tr><td style=\"white-space:nowrap\">4.2<a name=\"ctd-section-4.462\"> </a></td><td>Study Reports (Nonclinical)</td></tr><tr><td style=\"white-space:nowrap\">5.1<a name=\"ctd-section-5.461\"> </a></td><td>Table of Contents (Clinical)</td></tr><tr><td style=\"white-space:nowrap\">5.2<a name=\"ctd-section-5.462\"> </a></td><td>Tabular Listing of All Clinical Studies</td></tr><tr><td style=\"white-space:nowrap\">5.3<a name=\"ctd-section-5.463\"> </a></td><td>Clinical Study Reports</td></tr><tr><td style=\"white-space:nowrap\">5.3.5<a name=\"ctd-section-5.463.465\"> </a></td><td>Reports of Efficacy and Safety Studies</td></tr><tr><td style=\"white-space:nowrap\">5.3.5.1<a name=\"ctd-section-5.463.465.461\"> </a></td><td>Study Reports of Controlled Clinical Studies</td></tr><tr><td style=\"white-space:nowrap\">5.3.5.3<a name=\"ctd-section-5.463.465.463\"> </a></td><td>Reports of Analysis of Data from More than One Study</td></tr></table></div>"
  },
  "url" : "http://hl7.org/fhir/uv/apix/CodeSystem/ctd-section",
  "version" : "0.1.0",
  "name" : "APIX_CTD_Section",
  "title" : "APIX CTD/eCTD Section Code System",
  "status" : "active",
  "experimental" : false,
  "date" : "2025-11-24",
  "publisher" : "Gravitate Health Project",
  "contact" : [
    {
      "name" : "Gravitate Health Project",
      "telecom" : [
        {
          "system" : "url",
          "value" : "https://www.gravitatehealth.eu/"
        }
      ]
    }
  ],
  "description" : "Code system defining all relevant CTD/eCTD section codes used in APIX regulatory submissions to EMA, FDA, PMDA and other agencies. Based on ICH M4 guidelines.",
  "caseSensitive" : true,
  "content" : "complete",
  "concept" : [
    {
      "code" : "1.0",
      "display" : "Cover Letter"
    },
    {
      "code" : "1.2",
      "display" : "Administrative Information"
    },
    {
      "code" : "1.3.1",
      "display" : "SPC, Labelling and Package Leaflet"
    },
    {
      "code" : "1.3.2",
      "display" : "Mock-ups"
    },
    {
      "code" : "1.3.3",
      "display" : "Specimens"
    },
    {
      "code" : "1.4",
      "display" : "Information about the Experts"
    },
    {
      "code" : "1.8.1",
      "display" : "Risk Management Plan"
    },
    {
      "code" : "1.9",
      "display" : "Pharmacovigilance System"
    },
    {
      "code" : "2.2",
      "display" : "Introduction"
    },
    {
      "code" : "2.3",
      "display" : "Quality Overall Summary"
    },
    {
      "code" : "2.4",
      "display" : "Nonclinical Overview"
    },
    {
      "code" : "2.5",
      "display" : "Clinical Overview"
    },
    {
      "code" : "2.6",
      "display" : "Nonclinical Summary"
    },
    {
      "code" : "2.7",
      "display" : "Clinical Summary"
    },
    {
      "code" : "3.2.S.1",
      "display" : "General Information (Drug Substance)"
    },
    {
      "code" : "3.2.S.1.1",
      "display" : "Nomenclature"
    },
    {
      "code" : "3.2.S.1.2",
      "display" : "Structure"
    },
    {
      "code" : "3.2.S.1.3",
      "display" : "General Properties"
    },
    {
      "code" : "3.2.S.2",
      "display" : "Manufacture (Drug Substance)"
    },
    {
      "code" : "3.2.S.3",
      "display" : "Characterisation (Drug Substance)"
    },
    {
      "code" : "3.2.S.4",
      "display" : "Control of Drug Substance"
    },
    {
      "code" : "3.2.S.5",
      "display" : "Reference Standards or Materials"
    },
    {
      "code" : "3.2.S.6",
      "display" : "Container Closure System"
    },
    {
      "code" : "3.2.S.7",
      "display" : "Stability (Drug Substance)"
    },
    {
      "code" : "3.2.P.1",
      "display" : "Description and Composition of the Drug Product"
    },
    {
      "code" : "3.2.P.2",
      "display" : "Pharmaceutical Development"
    },
    {
      "code" : "3.2.P.3",
      "display" : "Manufacture (Drug Product)"
    },
    {
      "code" : "3.2.P.4",
      "display" : "Control of Excipients"
    },
    {
      "code" : "3.2.P.5",
      "display" : "Control of Drug Product"
    },
    {
      "code" : "3.2.P.5.1",
      "display" : "Specification(s)"
    },
    {
      "code" : "3.2.P.5.6",
      "display" : "Justification of Specification(s)"
    },
    {
      "code" : "3.2.P.8",
      "display" : "Stability (Drug Product)"
    },
    {
      "code" : "3.2.P.8.1",
      "display" : "Stability Summary and Conclusion"
    },
    {
      "code" : "3.2.P.8.2",
      "display" : "Post-approval Stability Protocol and Commitment"
    },
    {
      "code" : "3.2.P.8.3",
      "display" : "Stability Data"
    },
    {
      "code" : "3.2.A.1",
      "display" : "Facilities and Equipment"
    },
    {
      "code" : "3.2.A.2",
      "display" : "Adventitious Agents Safety Evaluation"
    },
    {
      "code" : "3.2.A.3",
      "display" : "Excipients"
    },
    {
      "code" : "3.2.R",
      "display" : "Regional Information"
    },
    {
      "code" : "4.1",
      "display" : "Table of Contents (Nonclinical)"
    },
    {
      "code" : "4.2",
      "display" : "Study Reports (Nonclinical)"
    },
    {
      "code" : "5.1",
      "display" : "Table of Contents (Clinical)"
    },
    {
      "code" : "5.2",
      "display" : "Tabular Listing of All Clinical Studies"
    },
    {
      "code" : "5.3",
      "display" : "Clinical Study Reports"
    },
    {
      "code" : "5.3.5",
      "display" : "Reports of Efficacy and Safety Studies"
    },
    {
      "code" : "5.3.5.1",
      "display" : "Study Reports of Controlled Clinical Studies"
    },
    {
      "code" : "5.3.5.3",
      "display" : "Reports of Analysis of Data from More than One Study"
    }
  ]
}