<?xml version="1.0" encoding="UTF-8"?>

<CodeSystem xmlns="http://hl7.org/fhir">
  <id value="substance-interaction-type"/>
  <meta>
    <lastUpdated value="2026-06-23T16:20:19.822+00:00"/>
  </meta>
  <text>
    <status value="generated"/>
    <div xmlns="http://www.w3.org/1999/xhtml">
      <p class="res-header-id">
        <b>Generated Narrative: CodeSystem substance-interaction-type</b>
      </p>
      <a name="substance-interaction-type"> </a>
      <a name="hcsubstance-interaction-type"> </a>
      <p>This case-sensitive code system 
        <code>http://hl7.org/fhir/substance-interaction-type</code> defines the following codes:
      </p>
      <table class="codes">
        <tr>
          <td style="white-space:nowrap">
            <b>Code</b>
          </td>
          <td>
            <b>Display</b>
          </td>
          <td>
            <b>Definition</b>
          </td>
        </tr>
        <tr>
          <td style="white-space:nowrap">binding
            <a name="substance-interaction-type-binding"> </a>
          </td>
          <td>Binding</td>
          <td>The substance binds to its target.</td>
        </tr>
        <tr>
          <td style="white-space:nowrap">inhibition
            <a name="substance-interaction-type-inhibition"> </a>
          </td>
          <td>Inhibition</td>
          <td>The substance inhibits the activity of its target.</td>
        </tr>
        <tr>
          <td style="white-space:nowrap">activation
            <a name="substance-interaction-type-activation"> </a>
          </td>
          <td>Activation</td>
          <td>The substance activates its target.</td>
        </tr>
        <tr>
          <td style="white-space:nowrap">agonist
            <a name="substance-interaction-type-agonist"> </a>
          </td>
          <td>Agonist</td>
          <td>The substance acts as an agonist of its target.</td>
        </tr>
        <tr>
          <td style="white-space:nowrap">antagonist
            <a name="substance-interaction-type-antagonist"> </a>
          </td>
          <td>Antagonist</td>
          <td>The substance acts as an antagonist of its target.</td>
        </tr>
        <tr>
          <td style="white-space:nowrap">substrate
            <a name="substance-interaction-type-substrate"> </a>
          </td>
          <td>Substrate</td>
          <td>The substance is a substrate of its target.</td>
        </tr>
        <tr>
          <td style="white-space:nowrap">allosteric-modulator
            <a name="substance-interaction-type-allosteric-modulator"> </a>
          </td>
          <td>Allosteric modulator</td>
          <td>The substance acts as an allosteric modulator of its target.</td>
        </tr>
      </table>
    </div>
  </text>
  <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-wg">
    <valueCode value="brr"/>
  </extension>
  <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status">
    <valueCode value="informative"/>
  </extension>
  <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm">
    <valueInteger value="1"/>
  </extension>
  <url value="http://hl7.org/fhir/substance-interaction-type"/>
  <version value="6.0.0-ballot4"/>
  <name value="SubstanceInteractionTypeExample"/>
  <title value="Substance Interaction Type"/>
  <status value="active"/>
  <experimental value="true"/>
  <date value="2026-06-23"/>
  <publisher value="HL7 (FHIR Project)"/>
  <contact>
    <telecom>
      <system value="url"/>
      <value value="http://hl7.org/fhir"/>
    </telecom>
    <telecom>
      <system value="email"/>
      <value value="fhir@lists.hl7.org"/>
    </telecom>
  </contact>
  <description value="The kind of interaction between a substance and its target, e.g. binding, inhibition, agonism."/>
  <jurisdiction>
    <coding>
      <system value="http://unstats.un.org/unsd/methods/m49/m49.htm"/>
      <code value="001"/>
      <display value="World"/>
    </coding>
  </jurisdiction>
  <caseSensitive value="true"/>
  <valueSet value="http://hl7.org/fhir/ValueSet/substance-interaction-type"/>
  <content value="complete"/>
  <concept>
    <code value="binding"/>
    <display value="Binding"/>
    <definition value="The substance binds to its target."/>
  </concept>
  <concept>
    <code value="inhibition"/>
    <display value="Inhibition"/>
    <definition value="The substance inhibits the activity of its target."/>
  </concept>
  <concept>
    <code value="activation"/>
    <display value="Activation"/>
    <definition value="The substance activates its target."/>
  </concept>
  <concept>
    <code value="agonist"/>
    <display value="Agonist"/>
    <definition value="The substance acts as an agonist of its target."/>
  </concept>
  <concept>
    <code value="antagonist"/>
    <display value="Antagonist"/>
    <definition value="The substance acts as an antagonist of its target."/>
  </concept>
  <concept>
    <code value="substrate"/>
    <display value="Substrate"/>
    <definition value="The substance is a substrate of its target."/>
  </concept>
  <concept>
    <code value="allosteric-modulator"/>
    <display value="Allosteric modulator"/>
    <definition value="The substance acts as an allosteric modulator of its target."/>
  </concept>
</CodeSystem>