@prefix fhir: <http://hl7.org/fhir/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

# - resource -------------------------------------------------------------------

<http://hl7.org/fhir/CodeSystem/oligo-nucleotide-type> a fhir:CodeSystem ;
  fhir:nodeRole fhir:treeRoot ;
  fhir:id [ fhir:v "oligo-nucleotide-type"] ; # 
  fhir:meta [
     fhir:lastUpdated [ fhir:v "2026-06-23T16:20:19.822+00:00"^^xsd:dateTime ]
  ] ; # 
  fhir:text [
     fhir:status [ fhir:v "generated" ] ;
     fhir:div [ fhir:v "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: CodeSystem oligo-nucleotide-type</b></p><a name=\"oligo-nucleotide-type\"> </a><a name=\"hcoligo-nucleotide-type\"> </a><p>This case-sensitive code system <code>http://hl7.org/fhir/oligo-nucleotide-type</code> defines the following codes:</p><table class=\"codes\"><tr><td style=\"white-space:nowrap\"><b>Code</b></td><td><b>Display</b></td><td><b>Definition</b></td></tr><tr><td style=\"white-space:nowrap\">antisense<a name=\"oligo-nucleotide-type-antisense\"> </a></td><td>Antisense oligonucleotide</td><td>An antisense oligonucleotide (ASO) that binds to a complementary mRNA sequence to inhibit gene expression.</td></tr><tr><td style=\"white-space:nowrap\">sirna<a name=\"oligo-nucleotide-type-sirna\"> </a></td><td>Small interfering RNA (siRNA)</td><td>A short double-stranded RNA that triggers degradation of a target mRNA through the RNA interference pathway.</td></tr><tr><td style=\"white-space:nowrap\">mirna<a name=\"oligo-nucleotide-type-mirna\"> </a></td><td>MicroRNA (miRNA)</td><td>A short non-coding RNA that regulates gene expression by base-pairing with target mRNAs.</td></tr><tr><td style=\"white-space:nowrap\">aptamer<a name=\"oligo-nucleotide-type-aptamer\"> </a></td><td>Aptamer</td><td>A short single-stranded oligonucleotide that binds a specific target through its three-dimensional structure.</td></tr><tr><td style=\"white-space:nowrap\">decoy<a name=\"oligo-nucleotide-type-decoy\"> </a></td><td>Decoy oligonucleotide</td><td>An oligonucleotide that mimics a regulatory binding site to sequester a transcription factor or other binding protein.</td></tr><tr><td style=\"white-space:nowrap\">ribozyme<a name=\"oligo-nucleotide-type-ribozyme\"> </a></td><td>Ribozyme / DNAzyme</td><td>A catalytic oligonucleotide capable of cleaving a target nucleic acid.</td></tr><tr><td style=\"white-space:nowrap\">gene-fragment<a name=\"oligo-nucleotide-type-gene-fragment\"> </a></td><td>Gene fragment</td><td>A fragment of a gene such as a promoter, enhancer, coding region or silencer.</td></tr></table></div>"^^rdf:XMLLiteral ]
  ] ; # 
  fhir:extension ( [
     fhir:url [
       fhir:v "http://hl7.org/fhir/StructureDefinition/structuredefinition-wg"^^xsd:anyURI ;
       fhir:l <http://hl7.org/fhir/StructureDefinition/structuredefinition-wg>
     ] ;
     fhir:value [
       a fhir:Code ;
       fhir:v "brr"
     ]
  ] [
     fhir:url [
       fhir:v "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"^^xsd:anyURI ;
       fhir:l <http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status>
     ] ;
     fhir:value [
       a fhir:Code ;
       fhir:v "informative"
     ]
  ] [
     fhir:url [
       fhir:v "http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm"^^xsd:anyURI ;
       fhir:l <http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm>
     ] ;
     fhir:value [
       a fhir:Integer ;
       fhir:v 1
     ]
  ] ) ; # 
  fhir:url [
     fhir:v "http://hl7.org/fhir/oligo-nucleotide-type"^^xsd:anyURI ;
     fhir:l <http://hl7.org/fhir/oligo-nucleotide-type>
  ] ; # 
  fhir:version [ fhir:v "6.0.0-ballot4"] ; # 
  fhir:name [ fhir:v "OligoNucleotideTypeExample"] ; # 
  fhir:title [ fhir:v "Oligonucleotide Type"] ; # 
  fhir:status [ fhir:v "active"] ; # 
  fhir:experimental [ fhir:v true] ; # 
  fhir:date [ fhir:v "2026-06-21"^^xsd:date] ; # 
  fhir:publisher [ fhir:v "HL7 (FHIR Project)"] ; # 
  fhir:contact ( [
     fhir:telecom ( [
       fhir:system [ fhir:v "url" ] ;
       fhir:value [ fhir:v "http://hl7.org/fhir" ]
     ] [
       fhir:system [ fhir:v "email" ] ;
       fhir:value [ fhir:v "fhir@lists.hl7.org" ]
     ] )
  ] ) ; # 
  fhir:description [ fhir:v "The class of oligonucleotide, where relevant (e.g. antisense, siRNA, aptamer)."] ; # 
  fhir:jurisdiction ( [
     fhir:coding ( [
       fhir:system [
         fhir:v "http://unstats.un.org/unsd/methods/m49/m49.htm"^^xsd:anyURI ;
         fhir:l <http://unstats.un.org/unsd/methods/m49/m49.htm>
       ] ;
       fhir:code [ fhir:v "001" ] ;
       fhir:display [ fhir:v "World" ]
     ] )
  ] ) ; # 
  fhir:caseSensitive [ fhir:v true] ; # 
  fhir:valueSet [
     fhir:v "http://hl7.org/fhir/ValueSet/oligo-nucleotide-type"^^xsd:anyURI ;
     fhir:l <http://hl7.org/fhir/ValueSet/oligo-nucleotide-type>
  ] ; # 
  fhir:hierarchyMeaning [] ; # 
  fhir:content [ fhir:v "complete"] ; # 
  fhir:concept ( [
     fhir:code [ fhir:v "antisense" ] ;
     fhir:display [ fhir:v "Antisense oligonucleotide" ] ;
     fhir:definition [ fhir:v "An antisense oligonucleotide (ASO) that binds to a complementary mRNA sequence to inhibit gene expression." ]
  ] [
     fhir:code [ fhir:v "sirna" ] ;
     fhir:display [ fhir:v "Small interfering RNA (siRNA)" ] ;
     fhir:definition [ fhir:v "A short double-stranded RNA that triggers degradation of a target mRNA through the RNA interference pathway." ]
  ] [
     fhir:code [ fhir:v "mirna" ] ;
     fhir:display [ fhir:v "MicroRNA (miRNA)" ] ;
     fhir:definition [ fhir:v "A short non-coding RNA that regulates gene expression by base-pairing with target mRNAs." ]
  ] [
     fhir:code [ fhir:v "aptamer" ] ;
     fhir:display [ fhir:v "Aptamer" ] ;
     fhir:definition [ fhir:v "A short single-stranded oligonucleotide that binds a specific target through its three-dimensional structure." ]
  ] [
     fhir:code [ fhir:v "decoy" ] ;
     fhir:display [ fhir:v "Decoy oligonucleotide" ] ;
     fhir:definition [ fhir:v "An oligonucleotide that mimics a regulatory binding site to sequester a transcription factor or other binding protein." ]
  ] [
     fhir:code [ fhir:v "ribozyme" ] ;
     fhir:display [ fhir:v "Ribozyme / DNAzyme" ] ;
     fhir:definition [ fhir:v "A catalytic oligonucleotide capable of cleaving a target nucleic acid." ]
  ] [
     fhir:code [ fhir:v "gene-fragment" ] ;
     fhir:display [ fhir:v "Gene fragment" ] ;
     fhir:definition [ fhir:v "A fragment of a gene such as a promoter, enhancer, coding region or silencer." ]
  ] ) . # 

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