{"caseSensitive":true,"concept":[{"code":"promoter","definition":"A DNA sequence that initiates and regulates transcription of a gene.","display":"Promoter"},{"code":"enhancer","definition":"A DNA sequence that increases the rate of transcription.","display":"Enhancer"},{"code":"silencer","definition":"A DNA sequence that reduces or prevents transcription.","display":"Silencer"},{"code":"terminator","definition":"A DNA sequence that signals the end of transcription.","display":"Terminator"},{"code":"repressor","definition":"A DNA sequence to which a repressor protein binds to inhibit transcription.","display":"Repressor binding site"},{"code":"coding-sequence","definition":"The portion of a gene that encodes a protein.","display":"Coding sequence (CDS)"},{"code":"intron","definition":"A non-coding sequence within a gene that is spliced out during mRNA processing.","display":"Intron"},{"code":"ribozyme","definition":"A catalytic RNA element.","display":"Ribozyme"}],"contact":[{"telecom":[{"system":"url","value":"http://hl7.org/fhir"},{"system":"email","value":"fhir@lists.hl7.org"}]}],"content":"complete","date":"2026-06-23","description":"The functional role of a DNA element within a gene therapy construct.","experimental":true,"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"brr"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"informative"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":1}],"id":"gene-element-type","jurisdiction":[{"coding":[{"code":"001","display":"World","system":"http://unstats.un.org/unsd/methods/m49/m49.htm"}]}],"meta":{"lastUpdated":"2026-06-23T16:20:19.822+00:00"},"name":"GeneElementTypeExample","publisher":"HL7 (FHIR Project)","resourceType":"CodeSystem","status":"active","text":{"div":"<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: CodeSystem gene-element-type</b></p><a name=\"gene-element-type\"> </a><a name=\"hcgene-element-type\"> </a><p>This case-sensitive code system <code>http://hl7.org/fhir/gene-element-type</code> defines the following codes:</p><table class=\"codes\"><tr><td style=\"white-space:nowrap\"><b>Code</b></td><td><b>Display</b></td><td><b>Definition</b></td></tr><tr><td style=\"white-space:nowrap\">promoter<a name=\"gene-element-type-promoter\"> </a></td><td>Promoter</td><td>A DNA sequence that initiates and regulates transcription of a gene.</td></tr><tr><td style=\"white-space:nowrap\">enhancer<a name=\"gene-element-type-enhancer\"> </a></td><td>Enhancer</td><td>A DNA sequence that increases the rate of transcription.</td></tr><tr><td style=\"white-space:nowrap\">silencer<a name=\"gene-element-type-silencer\"> </a></td><td>Silencer</td><td>A DNA sequence that reduces or prevents transcription.</td></tr><tr><td style=\"white-space:nowrap\">terminator<a name=\"gene-element-type-terminator\"> </a></td><td>Terminator</td><td>A DNA sequence that signals the end of transcription.</td></tr><tr><td style=\"white-space:nowrap\">repressor<a name=\"gene-element-type-repressor\"> </a></td><td>Repressor binding site</td><td>A DNA sequence to which a repressor protein binds to inhibit transcription.</td></tr><tr><td style=\"white-space:nowrap\">coding-sequence<a name=\"gene-element-type-coding-sequence\"> </a></td><td>Coding sequence (CDS)</td><td>The portion of a gene that encodes a protein.</td></tr><tr><td style=\"white-space:nowrap\">intron<a name=\"gene-element-type-intron\"> </a></td><td>Intron</td><td>A non-coding sequence within a gene that is spliced out during mRNA processing.</td></tr><tr><td style=\"white-space:nowrap\">ribozyme<a name=\"gene-element-type-ribozyme\"> </a></td><td>Ribozyme</td><td>A catalytic RNA element.</td></tr></table></div>","status":"generated"},"title":"Gene Element Type","url":"http://hl7.org/fhir/gene-element-type","valueSet":"http://hl7.org/fhir/ValueSet/gene-element-type","version":"6.0.0-ballot4"}