<?xml version="1.0" encoding="UTF-8"?>
<difference>
   <type name="Evidence" status="changed">
      <element path="Evidence.versionAlgorithm[x]" status="new"/>
      <element path="Evidence.name" status="new"/>
      <element old-name="citeAs[x]" path="Evidence.citeAs">
         <removed-type name="Reference(Citation)"/>
      </element>
      <element binding-status="changed"
               binding-valueset-changed="true"
               path="Evidence.status">
         <old-binding reference="http://hl7.org/fhir/ValueSet/publication-status|4.3.0"
                      strength="required"/>
         <new-binding reference="http://hl7.org/fhir/ValueSet/publication-status|6.0.0-ballot4"
                      strength="required"/>
      </element>
      <element path="Evidence.experimental" status="new"/>
      <element path="Evidence.recorder" status="new"/>
      <element path="Evidence.purpose" status="new"/>
      <element path="Evidence.copyright" status="new"/>
      <element path="Evidence.copyrightLabel" status="new"/>
      <element path="Evidence.relatesTo" status="new"/>
      <element path="Evidence.relatesTo.type" status="new"/>
      <element path="Evidence.relatesTo.target[x]" status="new"/>
      <element new-min="0" old-min="1" path="Evidence.variableDefinition"/>
      <element binding-status="changed"
               binding-strength-changed="true"
               binding-valueset-changed="true"
               path="Evidence.variableDefinition.variableRole">
         <removed-type name="CodeableConcept"/>
         <added-type name="code"/>
         <old-binding reference="http://hl7.org/fhir/ValueSet/variable-role"
                      strength="extensible"/>
         <new-binding reference="http://hl7.org/fhir/ValueSet/variable-role|6.0.0-ballot4"
                      strength="required"/>
      </element>
      <element path="Evidence.variableDefinition.roleSubtype" status="new"/>
      <element path="Evidence.variableDefinition.comparatorCategory" status="new"/>
      <element binding-status="removed"
               path="Evidence.variableDefinition.directnessMatch">
         <old-binding reference="http://hl7.org/fhir/ValueSet/directness"
                      strength="extensible"/>
      </element>
      <element binding-status="removed"
               new-max="*"
               old-max="1"
               path="Evidence.synthesisType">
         <old-binding reference="http://hl7.org/fhir/ValueSet/synthesis-type"
                      strength="extensible"/>
      </element>
      <element path="Evidence.studyDesign" status="new"/>
      <element path="Evidence.statistic.description">
         <removed-type name="string"/>
         <added-type name="markdown"/>
      </element>
      <element binding-status="removed" path="Evidence.statistic.statisticType">
         <old-binding reference="http://hl7.org/fhir/ValueSet/statistic-type"
                      strength="extensible"/>
      </element>
      <element path="Evidence.statistic.sampleSize.description">
         <removed-type name="string"/>
         <added-type name="markdown"/>
      </element>
      <element path="Evidence.statistic.sampleSize.numberAnalyzed" status="new"/>
      <element path="Evidence.statistic.attributeEstimate.description">
         <removed-type name="string"/>
         <added-type name="markdown"/>
      </element>
      <element binding-status="removed"
               path="Evidence.statistic.attributeEstimate.type">
         <old-binding reference="http://hl7.org/fhir/ValueSet/attribute-estimate-type"
                      strength="extensible"/>
      </element>
      <element binding-status="removed"
               path="Evidence.statistic.modelCharacteristic.code">
         <old-binding reference="http://hl7.org/fhir/ValueSet/statistic-model-code"
                      strength="extensible"/>
      </element>
      <element old-name="value" path="Evidence.statistic.modelCharacteristic.value[x]">
         <added-type name="Range"/>
         <added-type name="CodeableConcept"/>
      </element>
      <element path="Evidence.statistic.modelCharacteristic.intended" status="new"/>
      <element path="Evidence.statistic.modelCharacteristic.applied" status="new"/>
      <element binding-status="removed"
               path="Evidence.statistic.modelCharacteristic.variable.handling">
         <removed-type name="code"/>
         <added-type name="CodeableConcept"/>
         <old-binding reference="http://hl7.org/fhir/ValueSet/variable-handling|4.3.0"
                      strength="required"/>
      </element>
      <element path="Evidence.statistic.modelCharacteristic.attribute" status="new"/>
      <element path="Evidence.certainty.description">
         <removed-type name="string"/>
         <added-type name="markdown"/>
      </element>
      <element binding-status="removed" path="Evidence.certainty.type">
         <old-binding reference="http://hl7.org/fhir/ValueSet/certainty-type"
                      strength="extensible"/>
      </element>
      <element binding-status="removed" path="Evidence.certainty.rating">
         <old-binding reference="http://hl7.org/fhir/ValueSet/certainty-rating"
                      strength="extensible"/>
      </element>
      <element new-max="*" old-max="1" path="Evidence.certainty.rater"/>
      <element path="Evidence.relatedArtifact" status="deleted"/>
      <element path="Evidence.studyType" status="deleted"/>
      <element path="Evidence.statistic.modelCharacteristic.attributeEstimate"
               status="deleted"/>
   </type>
</difference>
