A single issue - either an indication, contraindication, interaction or an undesirable effect for a medicinal product, medication, device or procedure. A single issue - either an indication, contraindication, interaction or an undesirable effect for a medicinal product, medication, device or procedure. If the element is present, it must have either a @value, an @id, or extensions Business identifier for this issue. indication | contraindication | interaction | undesirable-effect | warning. A categorisation of the issue, primarily for dividing warnings into subject heading areas such as "Pregnancy and Lactation", "Overdose", "Effects on Ability to Drive and Use Machines". The medication, product, substance, device, procedure etc. for which this is an indication, contraindication, interaction, undesirable effect, or warning. Whether this is a current issue or one that has been retired etc. Describe the possible undesirable effects (negative outcomes) from the use of the medicinal product as treatment. Specifics for when this is an indication. Specifics for when this is a contraindication. Specifics for when this is an interaction. The population group to which this applies. Logic used by the clinical use definition. A critical piece of information about environmental, health or physical risks or hazards that serve as caution to the user. For example 'Do not operate heavy machinery', 'May cause drowsiness', or 'Get medical advice/attention if you feel unwell'. A single issue - either an indication, contraindication, interaction or an undesirable effect for a medicinal product, medication, device or procedure. The situation in which the undesirable effect may manifest. High level classification of the effect. How often the effect is seen. Actions for managing the undesirable effect. A single issue - either an indication, contraindication, interaction or an undesirable effect for a medicinal product, medication, device or procedure. The situation that is being documented as an indication for this item. The status of the disease or symptom for the indication, for example "chronic" or "metastatic". A comorbidity (concurrent condition) or coinfection as part of the indication. Where this repeats it means that any one of these is relevant, rather than all of them needing to be present. The intended effect, aim or strategy to be achieved. Timing or duration information, that may be associated with use with the indicated condition e.g. Adult patients suffering from myocardial infarction (from a few days until less than 35 days), ischaemic stroke (from 7 days until less than 6 months). An unwanted side effect or negative outcome that may happen if you use the drug (or other subject of this resource) for this indication. An expression that returns true or false, indicating whether the indication is applicable or not, after having applied its other elements. Information about the use of the medicinal product in relation to other therapies described as part of the contraindication. A single issue - either an indication, contraindication, interaction or an undesirable effect for a medicinal product, medication, device or procedure. The type of relationship between the medicinal product indication or contraindication and another therapy. Reference to a specific medication (active substance, medicinal product or class of products, biological, food etc.) as part of an indication or contraindication. A single issue - either an indication, contraindication, interaction or an undesirable effect for a medicinal product, medication, device or procedure. The situation that is being documented as contraindicating against this item. The status of the disease or symptom for the contraindication, for example "chronic" or "metastatic". A comorbidity (concurrent condition) or coinfection. Where this repeats it means that any one of these is relevant, rather than all of them needing to be present. The indication which this is a contraindication for. An expression that returns true or false, indicating whether the indication is applicable or not, after having applied its other elements. Actions for managing the contraindication. Information about the use of the medicinal product in relation to other therapies described as part of the contraindication. A single issue - either an indication, contraindication, interaction or an undesirable effect for a medicinal product, medication, device or procedure. The specific medication, product, food, substance etc. or laboratory test that interacts. The type of the interaction e.g. drug-drug interaction, drug-food interaction, drug-lab test interaction. The effect of the interaction, for example "reduced gastric absorption of primary medication". The incidence of the interaction, e.g. theoretical, observed. Actions for managing the interaction. The severity of the interaction. A single issue - either an indication, contraindication, interaction or an undesirable effect for a medicinal product, medication, device or procedure. The specific medication, product, food, substance etc. or laboratory test that interacts. The route by which the item is administered to cause the interaction. A single issue - either an indication, contraindication, interaction or an undesirable effect for a medicinal product, medication, device or procedure. A textual definition of this warning, with formatting. A coded or unformatted textual definition of this warning. Indication Contraindication Interaction Undesirable Effect Warning If the element is present, it must have either a @value, an @id, or extensions