<?xml version="1.0" encoding="UTF-8"?>

<ClinicalUseDefinition xmlns="http://hl7.org/fhir">
  <id value="example-contraindication"/>
  <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-wg">
    <valueCode value="brr"/>
  </extension>
  <type value="contraindication"/>
  <subject>
    <reference>
      <reference value="MedicinalProductDefinition/example"/>
    </reference>
  </subject>
  <contraindication>
    <diseaseSymptomProcedure>
      <concept>
        <text value="Concomitant treatment with any other anticoagulant agent"/>
      </concept>
    </diseaseSymptomProcedure>
    <indication>
      <diseaseSymptomProcedure>
        <concept>
          <text value="Stroke"/>
        </concept>
      </diseaseSymptomProcedure>
      <diseaseStatus/>
    </indication>
    <otherTherapy>
      <relationshipType>
        <coding>
          <system value="http://ema.europa.eu/example/therapyrelationshiptype"/>
          <code value="Co-therapy(with)"/>
        </coding>
      </relationshipType>
      <treatment>
        <concept>
          <coding>
            <system value="http://ema.europa.eu/example/medication"/>
            <code value="Oralanticoagulants"/>
          </coding>
        </concept>
      </treatment>
    </otherTherapy>
    <!--  or  -->
    <otherTherapy>
      <relationshipType>
        <coding>
          <system value="http://ema.europa.eu/example/therapyrelationshiptype"/>
          <code value="Co-therapy(with)"/>
        </coding>
      </relationshipType>
      <treatment>
        <concept>
          <coding>
            <system value="http://ema.europa.eu/example/medication"/>
            <code value="Lowmolecularweightheparins"/>
          </coding>
        </concept>
      </treatment>
    </otherTherapy>
  </contraindication>
</ClinicalUseDefinition>