{
  "resourceType": "CodeSystem",
  "id": "substance-interaction-type",
  "meta": {
    "lastUpdated": "2026-07-03T14:29:03.795+00:00"
  },
  "text": {
    "status": "generated",
    "div": "\u003cdiv xmlns\u003d\"http://www.w3.org/1999/xhtml\"\u003e\u003cp class\u003d\"res-header-id\"\u003e\u003cb\u003eGenerated Narrative: CodeSystem substance-interaction-type\u003c/b\u003e\u003c/p\u003e\u003ca name\u003d\"substance-interaction-type\"\u003e \u003c/a\u003e\u003ca name\u003d\"hcsubstance-interaction-type\"\u003e \u003c/a\u003e\u003cp\u003eThis case-sensitive code system \u003ccode\u003ehttp://hl7.org/fhir/substance-interaction-type\u003c/code\u003e defines the following codes:\u003c/p\u003e\u003ctable class\u003d\"codes\"\u003e\u003ctr\u003e\u003ctd style\u003d\"white-space:nowrap\"\u003e\u003cb\u003eCode\u003c/b\u003e\u003c/td\u003e\u003ctd\u003e\u003cb\u003eDisplay\u003c/b\u003e\u003c/td\u003e\u003ctd\u003e\u003cb\u003eDefinition\u003c/b\u003e\u003c/td\u003e\u003c/tr\u003e\u003ctr\u003e\u003ctd style\u003d\"white-space:nowrap\"\u003ebinding\u003ca name\u003d\"substance-interaction-type-binding\"\u003e \u003c/a\u003e\u003c/td\u003e\u003ctd\u003eBinding\u003c/td\u003e\u003ctd\u003eThe substance binds to its target.\u003c/td\u003e\u003c/tr\u003e\u003ctr\u003e\u003ctd style\u003d\"white-space:nowrap\"\u003einhibition\u003ca name\u003d\"substance-interaction-type-inhibition\"\u003e \u003c/a\u003e\u003c/td\u003e\u003ctd\u003eInhibition\u003c/td\u003e\u003ctd\u003eThe substance inhibits the activity of its target.\u003c/td\u003e\u003c/tr\u003e\u003ctr\u003e\u003ctd style\u003d\"white-space:nowrap\"\u003eactivation\u003ca name\u003d\"substance-interaction-type-activation\"\u003e \u003c/a\u003e\u003c/td\u003e\u003ctd\u003eActivation\u003c/td\u003e\u003ctd\u003eThe substance activates its target.\u003c/td\u003e\u003c/tr\u003e\u003ctr\u003e\u003ctd style\u003d\"white-space:nowrap\"\u003eagonist\u003ca name\u003d\"substance-interaction-type-agonist\"\u003e \u003c/a\u003e\u003c/td\u003e\u003ctd\u003eAgonist\u003c/td\u003e\u003ctd\u003eThe substance acts as an agonist of its target.\u003c/td\u003e\u003c/tr\u003e\u003ctr\u003e\u003ctd style\u003d\"white-space:nowrap\"\u003eantagonist\u003ca name\u003d\"substance-interaction-type-antagonist\"\u003e \u003c/a\u003e\u003c/td\u003e\u003ctd\u003eAntagonist\u003c/td\u003e\u003ctd\u003eThe substance acts as an antagonist of its target.\u003c/td\u003e\u003c/tr\u003e\u003ctr\u003e\u003ctd style\u003d\"white-space:nowrap\"\u003esubstrate\u003ca name\u003d\"substance-interaction-type-substrate\"\u003e \u003c/a\u003e\u003c/td\u003e\u003ctd\u003eSubstrate\u003c/td\u003e\u003ctd\u003eThe substance is a substrate of its target.\u003c/td\u003e\u003c/tr\u003e\u003ctr\u003e\u003ctd style\u003d\"white-space:nowrap\"\u003eallosteric-modulator\u003ca name\u003d\"substance-interaction-type-allosteric-modulator\"\u003e \u003c/a\u003e\u003c/td\u003e\u003ctd\u003eAllosteric modulator\u003c/td\u003e\u003ctd\u003eThe substance acts as an allosteric modulator of its target.\u003c/td\u003e\u003c/tr\u003e\u003c/table\u003e\u003c/div\u003e"
  },
  "extension": [
    {
      "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-wg",
      "valueCode": "brr"
    },
    {
      "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
      "valueCode": "informative"
    },
    {
      "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm",
      "valueInteger": 1
    }
  ],
  "url": "http://hl7.org/fhir/substance-interaction-type",
  "version": "6.0.0-ballot4",
  "name": "SubstanceInteractionTypeExample",
  "title": "Substance Interaction Type",
  "status": "active",
  "experimental": true,
  "date": "2026-06-23",
  "publisher": "HL7 (FHIR Project)",
  "contact": [
    {
      "telecom": [
        {
          "system": "url",
          "value": "http://hl7.org/fhir"
        },
        {
          "system": "email",
          "value": "fhir@lists.hl7.org"
        }
      ]
    }
  ],
  "description": "The kind of interaction between a substance and its target, e.g. binding, inhibition, agonism.",
  "jurisdiction": [
    {
      "coding": [
        {
          "system": "http://unstats.un.org/unsd/methods/m49/m49.htm",
          "code": "001",
          "display": "World"
        }
      ]
    }
  ],
  "caseSensitive": true,
  "valueSet": "http://hl7.org/fhir/ValueSet/substance-interaction-type",
  "content": "complete",
  "concept": [
    {
      "code": "binding",
      "display": "Binding",
      "definition": "The substance binds to its target."
    },
    {
      "code": "inhibition",
      "display": "Inhibition",
      "definition": "The substance inhibits the activity of its target."
    },
    {
      "code": "activation",
      "display": "Activation",
      "definition": "The substance activates its target."
    },
    {
      "code": "agonist",
      "display": "Agonist",
      "definition": "The substance acts as an agonist of its target."
    },
    {
      "code": "antagonist",
      "display": "Antagonist",
      "definition": "The substance acts as an antagonist of its target."
    },
    {
      "code": "substrate",
      "display": "Substrate",
      "definition": "The substance is a substrate of its target."
    },
    {
      "code": "allosteric-modulator",
      "display": "Allosteric modulator",
      "definition": "The substance acts as an allosteric modulator of its target."
    }
  ]
}